Page last updated: 2024-10-16

formic acid and Amyloid Deposits

formic acid has been researched along with Amyloid Deposits in 4 studies

formic acid: RN given refers to parent cpd
formic acid : The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects.

Research Excerpts

ExcerptRelevanceReference
"Formic acid (FA) pre-treatment, which is generally used to enable efficient detection of Aβ with IHC, induces structural modifications within the Aβ, as well as in AAF."1.39Immunohistochemical characterization of novel monoclonal antibodies against the N-terminus of amyloid β-peptide. ( Blankenstein, MA; Hoozemans, JJ; Korth, C; Prikulis, I; Rozemuller, AJ; Scheltens, P; Schenk, D; Twaalfhoven, HA; van Haastert, ES; van Royen, MR; Veerhuis, R; Verwey, NA; Wouters, D, 2013)
"However, disease-associated gliosis and deposition of misfolded prion protein PrP(Sc) were identical in infected Tg2576-mice and non-transgenic littermate controls."1.35Prion infection of mice transgenic for human APPSwe: increased accumulation of cortical formic acid extractable Abeta(1-42) and rapid scrapie disease development. ( Apelt, J; Baier, M; Bamme, T; Burwinkel, M; Gültner, S; Riemer, C; Schliebs, R; Schwarz, A, 2008)
"From 12 to 23 months, diffuse plaques, neuritic plaques with amyloid cores, and biochemically extracted Abeta42 and Abeta40 increase to levels like those observed in AD brains."1.31Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease. ( Ashe, KH; Kawarabayashi, T; Saido, TC; Shoji, M; Younkin, LH; Younkin, SG, 2001)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Verwey, NA1
Hoozemans, JJ1
Korth, C1
van Royen, MR1
Prikulis, I1
Wouters, D1
Twaalfhoven, HA1
van Haastert, ES1
Schenk, D1
Scheltens, P1
Rozemuller, AJ1
Blankenstein, MA1
Veerhuis, R1
Baier, M1
Apelt, J1
Riemer, C1
Gültner, S1
Schwarz, A1
Bamme, T1
Burwinkel, M1
Schliebs, R1
D'Andrea, MR1
Reiser, PA1
Polkovitch, DA1
Gumula, NA1
Branchide, B1
Hertzog, BM1
Schmidheiser, D1
Belkowski, S1
Gastard, MC1
Andrade-Gordon, P1
Kawarabayashi, T1
Younkin, LH1
Saido, TC1
Shoji, M1
Ashe, KH1
Younkin, SG1

Other Studies

4 other studies available for formic acid and Amyloid Deposits

ArticleYear
Immunohistochemical characterization of novel monoclonal antibodies against the N-terminus of amyloid β-peptide.
    Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, 2013, Volume: 20, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antibodies, Monoclonal; Capillaries; Cerebral Amy

2013
Prion infection of mice transgenic for human APPSwe: increased accumulation of cortical formic acid extractable Abeta(1-42) and rapid scrapie disease development.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2008, Volume: 26, Issue:7

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cerebral Cortex;

2008
The use of formic acid to embellish amyloid plaque detection in Alzheimer's disease tissues misguides key observations.
    Neuroscience letters, 2003, May-15, Volume: 342, Issue:1-2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Autopsy; Case-Control Studies; Fo

2003
Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Jan-15, Volume: 21, Issue:2

    Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Biomarkers

2001