formic acid has been researched along with Acute Confusional Senile Dementia in 22 studies
formic acid: RN given refers to parent cpd
formic acid : The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A rapid and sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for determination of Meserine ((-)-meptazinol phenylcarbamate), a novel potent inhibitor of acetylcholinesterase (AChE), was developed, validated, and applied to a pharmacokinetic study in mice brain." | 1.40 | Determination of Meserine, a new candidate for Alzheimer's disease in mice brain by liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic and tissue distribution study. ( Chen, H; Lv, H; Qiu, Z; Tang, Y; Wang, H; Xie, Q; Xu, J; Zhao, H; Zheng, Z, 2014) |
| "Formic acid (FA) pre-treatment, which is generally used to enable efficient detection of Aβ with IHC, induces structural modifications within the Aβ, as well as in AAF." | 1.39 | Immunohistochemical characterization of novel monoclonal antibodies against the N-terminus of amyloid β-peptide. ( Blankenstein, MA; Hoozemans, JJ; Korth, C; Prikulis, I; Rozemuller, AJ; Scheltens, P; Schenk, D; Twaalfhoven, HA; van Haastert, ES; van Royen, MR; Veerhuis, R; Verwey, NA; Wouters, D, 2013) |
| "However, disease-associated gliosis and deposition of misfolded prion protein PrP(Sc) were identical in infected Tg2576-mice and non-transgenic littermate controls." | 1.35 | Prion infection of mice transgenic for human APPSwe: increased accumulation of cortical formic acid extractable Abeta(1-42) and rapid scrapie disease development. ( Apelt, J; Baier, M; Bamme, T; Burwinkel, M; Gültner, S; Riemer, C; Schliebs, R; Schwarz, A, 2008) |
| "From 12 to 23 months, diffuse plaques, neuritic plaques with amyloid cores, and biochemically extracted Abeta42 and Abeta40 increase to levels like those observed in AD brains." | 1.31 | Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease. ( Ashe, KH; Kawarabayashi, T; Saido, TC; Shoji, M; Younkin, LH; Younkin, SG, 2001) |
| "In cases of progressive supranuclear palsy (PSP) and Alzheimer's disease (AD) the treatment of tissue sections with formic acid (FA) disclosed a neurofilament epitope in subcortical straight (SF) and paired helical (PHF) filaments." | 1.28 | Formic acid treatment exposes hidden neurofilament and tau epitopes in abnormal cytoskeletal filaments from patients with progressive supranuclear palsy and Alzheimer's disease. ( Cammarata, S; Mancardi, G; Tabaton, M, 1990) |
| "This formic acid pretreatment enhanced immunoreactivity of the amyloid deposits which reacted positively with specific antiserum." | 1.27 | Formic acid pretreatment enhances immunostaining of cerebral and systemic amyloids. ( Kitamoto, T; Ogomori, K; Prusiner, SB; Tateishi, J, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.09) | 18.7374 |
| 1990's | 6 (27.27) | 18.2507 |
| 2000's | 9 (40.91) | 29.6817 |
| 2010's | 3 (13.64) | 24.3611 |
| 2020's | 2 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Fernandes, AR | 1 |
| Dujardin, S | 1 |
| Maté de Gérando, A | 1 |
| Hyman, BT | 2 |
| Frosch, MP | 2 |
| Patzer, KH | 2 |
| Corbett, GT | 1 |
| Roy, A | 1 |
| Pahan, K | 1 |
| Verwey, NA | 1 |
| Hoozemans, JJ | 1 |
| Korth, C | 1 |
| van Royen, MR | 1 |
| Prikulis, I | 1 |
| Wouters, D | 1 |
| Twaalfhoven, HA | 1 |
| van Haastert, ES | 1 |
| Schenk, D | 1 |
| Scheltens, P | 1 |
| Rozemuller, AJ | 1 |
| Blankenstein, MA | 1 |
| Veerhuis, R | 1 |
| Zheng, Z | 1 |
| Tang, Y | 1 |
| Lv, H | 1 |
| Xu, J | 1 |
| Zhao, H | 1 |
| Xie, Q | 1 |
| Qiu, Z | 1 |
| Chen, H | 1 |
| Wang, H | 1 |
| Baier, M | 1 |
| Apelt, J | 1 |
| Riemer, C | 1 |
| Gültner, S | 1 |
| Schwarz, A | 1 |
| Bamme, T | 1 |
| Burwinkel, M | 1 |
| Schliebs, R | 1 |
| Christensen, DZ | 1 |
| Bayer, TA | 1 |
| Wirths, O | 1 |
| Ke, YD | 1 |
| Delerue, F | 1 |
| Gladbach, A | 1 |
| Götz, J | 1 |
| Ittner, LM | 1 |
| D'Andrea, MR | 1 |
| Reiser, PA | 1 |
| Polkovitch, DA | 1 |
| Gumula, NA | 1 |
| Branchide, B | 1 |
| Hertzog, BM | 1 |
| Schmidheiser, D | 1 |
| Belkowski, S | 1 |
| Gastard, MC | 1 |
| Andrade-Gordon, P | 1 |
| Sergeant, N | 1 |
| Bombois, S | 1 |
| Ghestem, A | 1 |
| Drobecq, H | 1 |
| Kostanjevecki, V | 1 |
| Missiaen, C | 1 |
| Wattez, A | 1 |
| David, JP | 1 |
| Vanmechelen, E | 1 |
| Sergheraert, C | 1 |
| Delacourte, A | 1 |
| Matsui, T | 1 |
| Ramasamy, K | 1 |
| Ingelsson, M | 1 |
| Fukumoto, H | 1 |
| Conrad, C | 1 |
| Irizarry, MC | 1 |
| Yuan, J | 1 |
| Ohyagi, Y | 1 |
| Tsuruta, Y | 1 |
| Motomura, K | 1 |
| Miyoshi, K | 1 |
| Kikuchi, H | 1 |
| Iwaki, T | 1 |
| Taniwaki, T | 1 |
| Kira, J | 1 |
| Iwamoto, N | 1 |
| Nishiyama, E | 1 |
| Ohwada, J | 1 |
| Arai, H | 1 |
| Smith, MA | 1 |
| Siedlak, SL | 1 |
| Richey, PL | 1 |
| Nagaraj, RH | 1 |
| Elhammer, A | 1 |
| Perry, G | 1 |
| Yang, LS | 1 |
| Gordon-Krajcer, W | 2 |
| Ksiezak-Reding, H | 2 |
| Mizuno, T | 1 |
| Haass, C | 1 |
| Michikawa, M | 1 |
| Yanagisawa, K | 1 |
| Yang, L | 1 |
| Kawarabayashi, T | 1 |
| Younkin, LH | 1 |
| Saido, TC | 1 |
| Shoji, M | 2 |
| Ashe, KH | 1 |
| Younkin, SG | 1 |
| Cammarata, S | 1 |
| Mancardi, G | 1 |
| Tabaton, M | 1 |
| Klunk, WE | 1 |
| Pettegrew, JW | 1 |
| Kitamoto, T | 1 |
| Ogomori, K | 1 |
| Tateishi, J | 1 |
| Prusiner, SB | 1 |
| Yamaguchi, H | 1 |
| Hirai, S | 1 |
| Morimatsu, M | 1 |
| Nakazato, Y | 1 |
22 other studies available for formic acid and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Impact of Sterilization Methods on the Seeding Ability of Human Tau Proteopathic Seeds.
Topics: Alzheimer Disease; Animals; Brain; Chromatography, Gel; Formates; HEK293 Cells; Humans; Mice; Mice, | 2021 |
Topics: Alzheimer Disease; Formates; Humans | 2022 |
Topics: Alzheimer Disease; Formates; Humans | 2022 |
Topics: Alzheimer Disease; Formates; Humans | 2022 |
Topics: Alzheimer Disease; Formates; Humans | 2022 |
Sodium phenylbutyrate enhances astrocytic neurotrophin synthesis via protein kinase C (PKC)-mediated activation of cAMP-response element-binding protein (CREB): implications for Alzheimer disease therapy.
Topics: Administration, Oral; Alzheimer Disease; Animals; Astrocytes; Brain-Derived Neurotrophic Factor; Cel | 2013 |
Immunohistochemical characterization of novel monoclonal antibodies against the N-terminus of amyloid β-peptide.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antibodies, Monoclonal; Capillaries; Cerebral Amy | 2013 |
Determination of Meserine, a new candidate for Alzheimer's disease in mice brain by liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic and tissue distribution study.
Topics: Alzheimer Disease; Animals; Area Under Curve; Brain; Calibration; Chemistry, Pharmaceutical; Chromat | 2014 |
Prion infection of mice transgenic for human APPSwe: increased accumulation of cortical formic acid extractable Abeta(1-42) and rapid scrapie disease development.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cerebral Cortex; | 2008 |
Formic acid is essential for immunohistochemical detection of aggregated intraneuronal Abeta peptides in mouse models of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Anim | 2009 |
Experimental diabetes mellitus exacerbates tau pathology in a transgenic mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Blood Glucose; Comorbidity; Diabetes Mellitus, Experimental; Disease Mod | 2009 |
The use of formic acid to embellish amyloid plaque detection in Alzheimer's disease tissues misguides key observations.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Autopsy; Case-Control Studies; Fo | 2003 |
Truncated beta-amyloid peptide species in pre-clinical Alzheimer's disease as new targets for the vaccination approach.
Topics: Alzheimer Disease; Alzheimer Vaccines; Amyloid beta-Peptides; Blotting, Western; Brain Chemistry; Di | 2003 |
Coordinated expression of caspase 8, 3 and 7 mRNA in temporal cortex of Alzheimer disease: relationship to formic acid extractable abeta42 levels.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Case-Control Studies; Caspases; E | 2006 |
Intraneuronal amyloid beta42 enhanced by heating but counteracted by formic acid.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Epitopes; Female; Formates; Hot T | 2007 |
Demonstration of CRP immunoreactivity in brains of Alzheimer's disease: immunohistochemical study using formic acid pretreatment of tissue sections.
Topics: Aged; Alzheimer Disease; Antibodies, Monoclonal; C-Reactive Protein; Fluorescent Antibody Technique; | 1994 |
Quantitative solubilization and analysis of insoluble paired helical filaments from Alzheimer disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alkalies; Alzheimer Disease; Cell Fractionation; Cross-L | 1996 |
Tau released from paired helical filaments with formic acid or guanidine is susceptible to calpain-mediated proteolysis.
Topics: Aged; Alzheimer Disease; Brain; Calpain; Female; Fetus; Formates; Guanidine; Humans; Immunohistochem | 1997 |
Cholesterol-dependent generation of a unique amyloid beta-protein from apically missorted amyloid precursor protein in MDCK cells.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cell Compartmenta | 1998 |
Conformation of paired helical filaments blocks dephosphorylation of epitopes shared with fetal tau except Ser199/202 and Ser202/Thr205.
Topics: Aged; Aged, 80 and over; Alkaline Phosphatase; Alzheimer Disease; Amino Acid Sequence; Brain; Epitop | 2000 |
Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Biomarkers | 2001 |
Formic acid treatment exposes hidden neurofilament and tau epitopes in abnormal cytoskeletal filaments from patients with progressive supranuclear palsy and Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Brain; Epitopes; Formates; Humans; Immunohistochemistry; Intermediate Filam | 1990 |
Alzheimer's beta-amyloid protein is covalently modified when dissolved in formic acid.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid; Amyloid beta-Peptides; Drug Stability; Formates; Hu | 1990 |
Formic acid pretreatment enhances immunostaining of cerebral and systemic amyloids.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Amyloidosis; Animals; Creutzfeldt-Jakob Syndrome; | 1987 |
Diffuse type of senile plaques in the cerebellum of Alzheimer-type dementia demonstrated by beta protein immunostain.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Cerebellum; Formates; Gr | 1989 |