Page last updated: 2024-08-21

formestane and Pregnancy

formestane has been researched along with Pregnancy in 34 studies

*Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. [MeSH]

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199018 (52.94)18.7374
1990's11 (32.35)18.2507
2000's3 (8.82)29.6817
2010's2 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benslimane, O; Gourvest, JF; Hartmann, C; Lesuisse, D; Philibert, D; Tric, B; Vevert, JP1
Bednarski, PJ; Nelson, SD1
Counsell, RE; Darby, MV; Lovett, JA1
Colombo, G; Dinis, TC; Neves, MA; Sá e Melo, ML1
Alcaro, S; Amaral, C; Baptista, T; Carvalho, RA; Correia da Silva, G; Costa, G; Roleira, FM; Tavares da Silva, EJ; Teixeira, NA; Varela, C1
An, J; Davies, HM; Egbuta, C; Ghosh, D; Griswold, J; Hubbell, S; Jiang, W; Lo, J; Morton, D; Valette, D; Xi, J1
Alfaidy, N; Challis, JR; Gibb, W; Gupta, S; Holloway, AC; Lye, SJ; Whittle, WL1
Choi, L; Haning, RV; Kiggens, AJ; Kuzma, DL; Summerville, JW2
Wu, JT1
Abul-Hajj, YJ2
Brodie, AM1
Covey, DF; Hood, WF2
Brodie, AM; Garrett, WM; Hendrickson, JR; Marcotte, PA; Robinson, CH; Tsai-Morris, CH1
Akira, S; Friedman, CI; Hayes, RA; Kim, MH; Lin, YC; Miller, K1
Aguado, LI; Carrizo, DG; Deis, RP; Rastrilla, AM; Stati, AO; Stocco, CO; Tellería, CM1
Enari, H; Ikeda, Y; Kashima, A; Kato, A; Konno, M; Niimura, K; Nitta, T; Sugita, N1
Gaillard, JL; Moslemi, S; Silberzahn, P1
Kobayashi, F; Smalley, KN; Zimniski, SJ1
Giussani, DA; Guller, S; Jenkins, SL; Nathanielsz, PW; Tame, JD; Winter, JA1
Goh, VH; Tong, TY1
Brodie, AM; Brodie, HJ; Schwarzel, WC; Shaikh, AA1
Geisert, RD; Morgan, GL; O'Neill, LA; Wettemann, RP; Zavy, MT1
Braun, DG; Bullion, KA; Osawa, Y1
Chen, SA; Pompon, D; Zhou, DJ1
Briatico, G; D'Alessio, R; Di Salle, E; Giudici, D; Lombardi, P; Ornati, G; Villa, V1
Akiyama, I; Sakuma, Y; Takahashi, Y; Yamanaka, H1
Oakey, RE; Purohit, A1
Albrecht, ED; Anderson, LD; Pepe, GJ; Wunsch, DM1
Croxatto, HB; Forcelledo, ML1
France, JT; Magness, RR; Mason, JI; Murry, BA; Rosenfeld, CR1
Brodie, AM; Garrett, WM; Wing, LY1

Other Studies

34 other study(ies) available for formestane and Pregnancy

ArticleYear
Synthesis and evaluation of a new series of mechanism-based aromatase inhibitors.
    Journal of medicinal chemistry, 1992, May-01, Volume: 35, Issue:9

    Topics: Androstenedione; Animals; Aromatase Inhibitors; Female; Humans; Microsomes; Placenta; Pregnancy; Rats; Rats, Inbred Strains

1992
Interactions of thiol-containing androgens with human placental aromatase.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:1

    Topics: Androstenedione; Aromatase Inhibitors; Chemical Phenomena; Chemistry; Drug Interactions; Female; Humans; In Vitro Techniques; Microsomes; Paraoxon; Placenta; Pregnancy; Structure-Activity Relationship; Sulfhydryl Compounds; Testosterone Congeners

1989
Synthesis and evaluation of 19-aza- and 19-aminoandrostenedione analogues as potential aromatase inhibitors.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:6

    Topics: Androstenedione; Aromatase Inhibitors; Estrenes; Female; Humans; Kinetics; Microsomes; Oxidoreductases; Placenta; Pregnancy

1984
An efficient steroid pharmacophore-based strategy to identify new aromatase inhibitors.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:10

    Topics: Androstenedione; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Drug Design; Female; Humans; Models, Molecular; Placenta; Pregnancy; Structure-Activity Relationship

2009
New structure-activity relationships of A- and D-ring modified steroidal aromatase inhibitors: design, synthesis, and biochemical evaluation.
    Journal of medicinal chemistry, 2012, Apr-26, Volume: 55, Issue:8

    Topics: Androstenedione; Aromatase; Aromatase Inhibitors; Binding Sites; Epoxy Compounds; Female; Humans; Inhibitory Concentration 50; Kinetics; Microsomes; Models, Molecular; Placenta; Pregnancy; Structure-Activity Relationship

2012
Novel aromatase inhibitors by structure-guided design.
    Journal of medicinal chemistry, 2012, Oct-11, Volume: 55, Issue:19

    Topics: Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Cell Line, Tumor; Crystallography, X-Ray; Drug Design; Drug Screening Assays, Antitumor; Female; Humans; Molecular Docking Simulation; Molecular Structure; Placenta; Pregnancy; Protein Binding; Stereoisomerism; Structure-Activity Relationship

2012
Effects of cortisol and oestradiol on hepatic 11beta-hydroxysteroid dehydrogenase type 1 and glucocorticoid receptor proteins in late-gestation sheep fetus.
    The Journal of endocrinology, 2003, Volume: 176, Issue:2

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Analysis of Variance; Androstenedione; Animals; Aromatase Inhibitors; Blotting, Western; Enzyme Inhibitors; Estradiol; Female; Gestational Age; Hydrocortisone; Hydroxysteroid Dehydrogenases; Immunohistochemistry; Liver; Microsomes, Liver; Pregnancy; Receptors, Glucocorticoid; Sheep; Stimulation, Chemical

2003
Effects of dibutyryl cAMP, LHRH, and aromatase inhibitor on simultaneous outputs of prostaglandin F2 alpha, and 13,14-dihydro-15-keto-prostaglandin F2 alpha by term placental explants.
    Prostaglandins, 1982, Volume: 23, Issue:1

    Topics: Androstenedione; Aromatase Inhibitors; Bucladesine; Chorionic Gonadotropin; Culture Techniques; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dinoprost; Female; Gonadotropin-Releasing Hormone; Humans; Kinetics; Lipoproteins, LDL; Placenta; Pregnancy; Prostaglandins F

1982
Effects of dibutyryl adenosine 3',5'-monophosphate, luteinizing hormone-releasing hormone, and aromatase inhibitor on simultaneous outputs of progesterone, 17 beta-estradiol, and human chorionic gonadotropin by term placental explants.
    The Journal of clinical endocrinology and metabolism, 1982, Volume: 55, Issue:2

    Topics: Androstenedione; Bucladesine; Cholesterol; Cholesterol, LDL; Chorionic Gonadotropin; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Drug Synergism; Estradiol; Female; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Humans; Lipoproteins, LDL; Placenta; Pregnancy; Progesterone

1982
Induction of implantation by aromatase inhibitors in ovariectomized mice.
    Journal of reproduction and fertility, 1984, Volume: 72, Issue:2

    Topics: Androstatrienes; Androstenedione; Animals; Aromatase Inhibitors; Castration; Embryo Implantation; Female; Mice; Mice, Inbred Strains; Oxidoreductases; Pregnancy; Progesterone; Testosterone

1984
Studies on the mechanism of action of the aromatase inhibitor, 4-hydroxyandrostenedione.
    Steroids, 1983, Volume: 41, Issue:6

    Topics: Androstenedione; Aromatase Inhibitors; Female; Humans; Microsomes; Oxidoreductases; Placenta; Pregnancy

1983
Overview of recent development of aromatase inhibitors.
    Cancer research, 1982, Volume: 42, Issue:8 Suppl

    Topics: Aminoglutethimide; Androstatrienes; Androstenedione; Animals; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; In Vitro Techniques; Macaca mulatta; Male; Oxidoreductases; Pregnancy; Rats

1982
A new hypothesis based on suicide substrate inhibitor studies for the mechanism of action of aromatase.
    Cancer research, 1982, Volume: 42, Issue:8 Suppl

    Topics: Androstadienes; Androstatrienes; Androstenedione; Androstenes; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Female; Humans; Kinetics; Microsomes; Oxidoreductases; Placenta; Pregnancy; Structure-Activity Relationship; Testolactone

1982
Aromatase enzyme catalysis is involved in the potent inhibition of estrogen biosynthesis caused by 4-acetoxy- and 4-hydroxy-4-androstene-3, 17-dione.
    Molecular pharmacology, 1982, Volume: 21, Issue:1

    Topics: Androstenedione; Aromatase Inhibitors; Catalysis; Estrogens; Female; Humans; In Vitro Techniques; Kinetics; Microsomes; Oxidoreductases; Placenta; Pregnancy; Time Factors

1982
Inactivation of aromatase in vitro by 4-hydroxy-4-androstene-3,17-dione and 4-acetoxy-4-androstene-3,17-dione and sustained effects in vivo.
    Steroids, 1981, Volume: 38, Issue:6

    Topics: Androstenedione; Animals; Aromatase Inhibitors; Cell-Free System; Female; Humans; Microsomes; Ovary; Oxidoreductases; Placenta; Pregnancy; Rats; Time Factors

1981
Inhibition of androgen aromatization in human breast cancer.
    Journal of steroid biochemistry, 1980, Volume: 13, Issue:12

    Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Carbon Radioisotopes; Estradiol; Estrone; Female; Humans; Kinetics; Microsomes; Oxidoreductases; Placenta; Pregnancy

1980
Pregnancy can be established in superovulated adult rats treated with progesterone and an aromatase inhibitor.
    Life sciences, 1993, Volume: 52, Issue:1

    Topics: Analysis of Variance; Androstenedione; Animals; Aromatase Inhibitors; Embryo Implantation; Estradiol; Female; Pregnancy; Pregnancy Maintenance; Pregnancy, Animal; Progesterone; Rats; Rats, Sprague-Dawley; Superovulation

1993
Dual regulation of luteal progesterone production by androstenedione during spontaneous and RU486-induced luteolysis in pregnant rats.
    The Journal of steroid biochemistry and molecular biology, 1995, Volume: 55, Issue:3-4

    Topics: 17-Hydroxysteroid Dehydrogenases; 20-alpha-Hydroxysteroid Dehydrogenase; 20-Hydroxysteroid Dehydrogenases; Adrenalectomy; Androstenedione; Animals; Aromatase Inhibitors; Cells, Cultured; Corpus Luteum; Dihydrotestosterone; Estradiol; Female; Hormone Antagonists; Luteolysis; Luteolytic Agents; Menstruation-Inducing Agents; Mifepristone; Organ Size; Polyunsaturated Alkamides; Pregnancy; Pregnancy, Animal; Progesterone; Rats; Rats, Wistar; Testosterone

1995
Aromatase inhibitors: synthesis, biological activity, and structure of 1,2-imidazolylmethylcyclopentanol derivatives.
    Chemical & pharmaceutical bulletin, 1995, Volume: 43, Issue:12

    Topics: Androstenedione; Aromatase Inhibitors; Crystallography, X-Ray; Cyclopentanes; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Microsomes; Placenta; Pregnancy

1995
The synthesis of 19-norandrostenedione from dehydroepiandrosterone in equine placenta is inhibited by aromatase inhibitors 4-hydroxyandrostenedione and fadrozole.
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 1995, Volume: 112, Issue:4

    Topics: Androstenedione; Animals; Aromatase Inhibitors; Dehydroepiandrosterone; Enzyme Inhibitors; Fadrozole; Female; Horses; Placenta; Pregnancy

1995
Characterization of oviductal aromatase in the northern leopard frog, Rana pipiens.
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 1996, Volume: 113, Issue:3

    Topics: Androstenedione; Animals; Aromatase; Enzyme Inhibitors; Female; Humans; Hydrogen-Ion Concentration; Kinetics; Microsomes; Oviducts; Placenta; Pregnancy; Rana pipiens; Thermodynamics

1996
Local paracrine effects of estradiol are central to parturition in the rhesus monkey.
    Nature medicine, 1998, Volume: 4, Issue:4

    Topics: Androstenedione; Animals; Aromatase Inhibitors; Electromyography; Enzyme Inhibitors; Estradiol; Female; Humans; Infusions, Intravenous; Labor, Obstetric; Macaca mulatta; Myometrium; Oxytocin; Pregnancy; Progesterone; Uterine Contraction

1998
Effects of 4-hydroxyandrostenedione and hyperstimulation with pregnant mare serum gonadotrophin on early embryonic development in rats.
    Canadian journal of physiology and pharmacology, 2001, Volume: 79, Issue:9

    Topics: Androstenedione; Animals; Aromatase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Estradiol; Female; Gonadotropins, Equine; Pregnancy; Rats; Rats, Wistar

2001
The effect of an aromatase inhibitor, 4-hydroxy-4-androstene-3,17-dione, on estrogen-dependent processes in reproduction and breast cancer.
    Endocrinology, 1977, Volume: 100, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstenedione; Animals; Aromatase Inhibitors; Body Weight; Embryo Implantation; Estrogens; Female; Humans; Male; Mammary Neoplasms, Experimental; Pregnancy; Proestrus; Rats

1977
Effect of estrogen inhibitors on conceptus estrogen synthesis and development in the gilt.
    Domestic animal endocrinology, 1991, Volume: 8, Issue:1

    Topics: Acid Phosphatase; Androstenedione; Animals; Aromatase Inhibitors; Blastocyst; Calcium; Clomiphene; Dose-Response Relationship, Drug; Electrophoresis, Gel, Two-Dimensional; Embryonic and Fetal Development; Estrogen Antagonists; Estrogens; Female; Least-Squares Analysis; Piperidines; Pregnancy; Pregnancy Proteins; Pregnancy, Animal; Pyrimidines; Raloxifene Hydrochloride; Swine

1991
Reversible inhibition of human placental microsomal aromatase by CGS 18320B and other non-steroidal compounds.
    Endocrine research, 1990, Volume: 16, Issue:2

    Topics: Androstenedione; Aromatase Inhibitors; Binding Sites; Binding, Competitive; Fadrozole; Female; Glutethimide; Humans; Imidazoles; Kinetics; Microsomes; Molecular Structure; Nitriles; Placenta; Pregnancy

1990
Stable expression of human aromatase complementary DNA in mammalian cells: a useful system for aromatase inhibitor screening.
    Cancer research, 1990, Nov-01, Volume: 50, Issue:21

    Topics: Aminoglutethimide; Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Base Sequence; Blotting, Southern; Cricetinae; Cricetulus; DNA; Female; Gene Expression; Humans; Kinetics; Molecular Sequence Data; Ovary; Placenta; Plasmids; Polymerase Chain Reaction; Pregnancy; Transfection; Tumor Cells, Cultured

1990
4-Aminoandrostenedione derivatives: a novel class of irreversible aromatase inhibitors. Comparison with FCE 24304 and 4-hydroxyandrostenedione.
    The Journal of steroid biochemistry and molecular biology, 1990, Nov-20, Volume: 37, Issue:3

    Topics: Androstadienes; Androstenedione; Animals; Aromatase Inhibitors; Female; Male; Pregnancy; Rats; Rats, Inbred Strains

1990
Brain aromatase activity and behavioral consequences in the male rat treated in utero with 4-hydroxy-androstenedione.
    Endocrinologia japonica, 1989, Volume: 36, Issue:1

    Topics: Androstenedione; Animals; Aromatase; Brain; Female; Genitalia, Male; Hypothalamus; Male; Maternal-Fetal Exchange; Pregnancy; Preoptic Area; Rats; Rats, Inbred Strains; Sex Differentiation; Sexual Behavior, Animal; Testosterone

1989
Evidence for separate sites for aromatisation of androstenedione and 16 alpha-hydroxyandrostenedione in human placental microsomes.
    Journal of steroid biochemistry, 1989, Volume: 33, Issue:3

    Topics: Androstenedione; Aromatase; Aromatase Inhibitors; Estradiol; Estriol; Estrone; Female; Humans; Hydroxyestrones; In Vitro Techniques; Kinetics; Microsomes; Placenta; Pregnancy; Radioimmunoassay

1989
Regulation of progesterone formation by human placental cells in culture.
    Endocrinology, 1986, Volume: 119, Issue:3

    Topics: Androstenedione; Cells, Cultured; Dehydroepiandrosterone; Dihydrotestosterone; DNA; Estradiol; Estrogen Antagonists; Ethamoxytriphetol; Female; Humans; Placenta; Pregnancy; Progesterone; Time Factors

1986
Effects of 4-hydroxyandrostenedione and exogenous testosterone on blood concentrations of oestradiol and oviducal embryo transport in the rat.
    The Journal of endocrinology, 1988, Volume: 118, Issue:1

    Topics: Androstenedione; Animals; Blastocyst; Estradiol; Female; Oviducts; Ovum Transport; Pregnancy; Rats; Rats, Inbred Strains; Testosterone

1988
Ovine placental aromatase: studies of activity levels, kinetic characteristics and effects of aromatase inhibitors.
    Journal of steroid biochemistry, 1987, Volume: 28, Issue:2

    Topics: Androstenedione; Animals; Antifungal Agents; Aromatase; Aromatase Inhibitors; Female; Humans; Imidazoles; Kinetics; Microsomes; Placenta; Pregnancy; Sheep; Subcellular Fractions

1987
Effects of aromatase inhibitors, aminoglutethimide, and 4-hydroxyandrostenedione on cyclic rats and rats with 7,12-dimethylbenz(a)anthracene-induced mammary tumors.
    Cancer research, 1985, Volume: 45, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoglutethimide; Androstenedione; Animals; Aromatase Inhibitors; Estradiol; Estrus; Female; Luteinizing Hormone; Mammary Neoplasms, Experimental; Oxidoreductases; Pregnancy; Rats; Rats, Inbred Strains

1985