Page last updated: 2024-08-21

formestane and Breast Cancer

formestane has been researched along with Breast Cancer in 149 studies

Research

Studies (149)

Timeframe	Studies, this research(%)	All Research%
pre-1990	25 (16.78)	18.7374
1990's	88 (59.06)	18.2507
2000's	26 (17.45)	29.6817
2010's	9 (6.04)	24.3611
2020's	1 (0.67)	2.80

Authors

Authors	Studies
Colombo, G; Dinis, TC; Neves, MA; Sá e Melo, ML	1
Marti, A; Martin, GD; Narvaez, J	1
Ćelić, AS; Djurendić, EA; Jakimov, DS; Klisurić, OR; Nikolić, AR; Penov Gaši, KM; Petri, ET; Sakač, MN	1
Barmade, MA; Murumkar, PR; Tamboli, RS; Yadav, MR	1
Ajduković, JJ; Aleksić, LD; Bogdanović, GM; Djurendić, EA; Jakimov, DS; Jovanović-Šanta, SS; Kojić, VV; Penov Gaši, KM; Sakač, MN	1
Alcaro, S; Amaral, C; Carvalho, RA; Correia-da-Silva, G; Costa, G; Costa, SC; Roleira, FM; Tavares-da-Silva, EJ; Teixeira, NA; Varela, CL	1
Chen, JZ; Khan, MZI; Nazli, A; Uzair, M	1
Abderrahman, B; Jordan, VC	1
Bao, Z; Deng, H; Gao, L; Li, J; Li, X; Liu, L; Nie, D; Rong, Z; Teichmann, AT; Wang, G; Wieland, FH; Yang, Y	1
Abrams, DN; Joshua, AV; McEwan, AJ; Sharma, SK; Zheng, W	1
Cavaliere, C; Corvigno, S; Galgani, M; Limite, G; Nardone, A; Veneziani, BM	1
Cheng, FX; Fu, J; Li, WH; Liu, GX; Shen, ZH; Tang, Y	1
Jiang, Z; Liu, X; Song, S; Wang, T; Wu, S; Yu, J	1
Briand, P; Jensen, J; Kitlen, JW; Labrie, F; Lykkesfeldt, AE	1
Burton, G; Kleeberg, U; Mauriac, L; Osborne, CK; Robertson, JF; Vergote, I	1
Carlini, P; Cognetti, F; Colella, E; Di Cosimo, S; Fabi, A; Ferretti, G; Frassoldati, A; Papaldo, P; Romiti, A; Ruggeri, EM; Tomao, S; Tonachella, R	1
Bajetta, E; Bichisao, E; Bidoli, P; Bombardieri, E; La Torre, I; Longarini, R; Martinetti, A; Portale, T; Seregni, E; Zilembo, N	1
Delozier, T; Khayat, D; Spano, JP	1
Bria, E; Carlini, P; Cognetti, F; Di Cosimo, S; Fabi, A; Felici, A; Ferretti, G; Giannarelli, D; Milella, M; Mottolese, M; Nisticò, C; Papaldo, P; Ruggeri, EM; Terzoli, E	1
Andrews, S; Braun, DP; Crist, KA; Parker, J; Shaheen, F; Staren, ED	1
Ioannidis, JP; Mauri, D; Pavlidis, N; Polyzos, NP	1
Prosperi, JR; Robertson, FM	1
Freudenstein, J; Nisslein, T	1
Dutta, U; Pant, K	1
Cavaliere, C; Ciardiello, F; Corvigno, S; Criniti, V; De Placido, S; Limite, G; Nardone, A; Picarelli, S; Tortora, G; Veneziani, BM	1
Brodie, A; Coombes, RC; Dowsett, M; Gazet, JC; Goss, P	1
Abul-Hajj, YJ	2
Feil, PD; Santen, RJ; Santner, SJ; Tilson-Mallett, N	1
Brodie, AM	3
Covey, DF; Hood, WF	1
Covey, DF; Etre, LA; MacIndoe, JH; Woods, GR	1
Covey, DF; Davis, SP; Killinger, DW; Perel, E	1
Murray, R; Pitt, P	2
McTavish, D; Wiseman, LR	1
Dowsett, M; Jacobs, S; Lonning, PE; MacNeill, FA; Powles, TJ	1
Bajetta, E; Biasi, G; Bichisao, E; Bono, A; Buzzoni, R; Dolci, S; Laffranchi, A; Noberasco, C; Vicario, G; Zilembo, N	1
Attili, A; Bajetta, E; Bartoli, C; Buzzoni, R; Ferrari, L; Lepera, P; Martinetti, A; Noberasco, C; Sacchini, V; Zilembo, N	1
Alberola Candel, V; Calabresi, F; Delozier, T; Feuilhade, F; Freue, M; Goss, P; Mauriac, L; Michel, RT; Pérez Carrión, R; Santos, R	1
Dowsett, M	4
Höffken, K; Jonat, W; Possinger, K	1
Miller, WR; Parker, MG; Sourdaine, P; Telford, J	1
Bajetta, E; Buzzoni, R; Celio, L; Dolci, S; Ferrari, L; Laffranchi, A; Noberasco, C; Vicario, G; Zilembo, N	1
Brodie, AM; Santen, RJ	2
Reed, MJ	1
Coombes, RC; Dowsett, M	1
Bajetta, E; Buzzoni, R; Celio, L; Cerrotta, AM; Ferrari, L; Galante, E; Martinetti, A; Noberasco, C; Orefice, S; Zilembo, N	1
Bajetta, E; Bartoli, C; Buzzoni, R; Celio, L; Di Leo, A; Merson, M; Moglia, D; Noberasco, C; Sacchini, V; Zilembo, N	1
Adlercreutz, H; Fotsis, T; Johannessen, DC; Lønning, PE	1
Dowsett, M; Jacobs, S; Lønning, PE; MacNeill, FA; Powles, TJ	1
Kanno, H; Kim, T; Kitawaki, J; Noguchi, T; Okada, H; Yamamoto, T	1
Brodie, A; Yue, W	1
Bajetta, E; Bichisao, E; Buzzoni, R; Celio, L; Noberasco, C; Zilembo, N	1
Höffken, K	1
Ekse, D; Lønning, PE	1
Detre, S; Dowsett, M; Grimshaw, R; Lee, K; Macaulay, VM; Rowlands, M	1
Coombes, RC; Corbishley, C; Ford, HT; Gazet, JC; Griffin, M; Lowndes, S; Makinde, V; Quilliam, J; Sutcliffe, R	1
Goa, KL; Wiseman, LR	1
Detre, S; Dowsett, M; Grimshaw, R; Rowlands, M	1
Frost, VJ; Helle, SI; Holly, JM; Lønning, PE; van der Stappen, JW	1
Anker, G; Geisler, J; Johannessen, DC; Lønning, PE	1
Brankin, E; Gallagher, A; Soukop, M	1
Rose, C	1
Bajetta, E; Bombardieri, E; Ferrari, L; Martinetti, A; Massaron, S; Noberasco, C; Rimassa, L; Seregni, E; Zilembo, N	1
Amichetti, M; Attili, A; Bajetta, E; Barni, S; Bichisao, E; Bolelli, GF; Bombardieri, E; Buzzoni, R; Comella, G; D'Aprile, M; Ferrari, L; Jirillo, A; Martinetti, A; Noberasco, C; Schieppati, G; Zilembo, N	1
Buzdar, AU; Roseman, BJ; Singletary, SE	1
Bonnefoi, H; Castiglione, M; Cavalli, F; Fey, MF; Goldhirsch, A; Hsu-Schmitz, SF; Löhnert, T; Morant, R; Thürlimann, B	1
Rubens, RD	1
Anderson, ED; Anderson, TJ; Cameron, DA; Chetty, U; Forrest, AP; Hawkins, RA; Leonard, RC; Levack, P	1
Aparicio, LA; Carrion, RP; Dodwell, DJ; Dowsett, M; Kleeberg, UR; Robertson, JF; Vorobiof, DA	1
Dickson, RB; El-Ashry, D; Hannum, RS; Kern, FG; Kharbanda, S; Lopez, CA; Lorant, LA; McLeskey, SW; Tobias, CA; Trock, BJ; Zhang, L	1
Lønning, PE	1
Alonso, MC; Español, I; Muñíz-Díaz, E; Pujol-Moix, N	1
Brodie, AM; Grigoryev, DN; Long, BJ; Thiantanawat, A; Tilghman, SL; Yue, W	1
Coombes, RC	2
Anker, GB; Johannessen, DC; Lien, EA; Lonning, PE; Refsum, H; Ueland, PM	1
Andrés, E; Dufour, P; Goichot, B; Imler, M; Kurtz, JE; Schlienger, JL	1
Brodie, AM; Dehal, SS; Kupfer, D	1
Blijham, GH; de Jong, PC	1
Coombes, RC; Harper-Wynne, C	1
Coombes, RC; Doody, D; Dowsett, M; English, J; Howes, A; Miall, S	1
Bernhard, J; Bonnefoi, H; Castiglione-Gertsch, M; Cavalli, F; Fey, MF; Goldhirsch, A; Hürny, C; Morant, R; Schmitz, SF; Thürlimann, B	2
Bonneterre, J; Feutrie, ML	1
Calvo, L; Clack, G; Dodwell, DJ; Dowsett, M; Kleeberg, UR; Perez-Carrion, R; Robertson, JF; Vorobiof, DA	1
Brodie, AM; Njar, VC	1
Coombes, RC; Dowsett, M; Harper-Wynne, C	1
Harvey, HA; Santen, RJ	1
Bajetta, E; Bichisao, E; Pozzi, P; Toffolatti, L; Zilembo, N	1
Joseph, JK; Lim, AK	1
Audisio, RA; Castiglione, F; Comandini, D; Granetto, C; Repetto, L; Ross, R; Venturino, A	1
Bajetta, E; Bombardieri, E; Celio, L; Di Bartolomeo, M; Ferrari, L; Mariani, L; Martinetti, A; Miceli, R; Pozzi, P; Seregni, E; Toffolatti, L; Zilembo, N	1
Klinga, K; Mayer, D; Morfin, R; Schmitt, M; Schnarr, B	1
Kerbrat, P; Lefeuvre, C	1
Blum, W; Faigle, JW; Galli, B; Geisler, J; Gschwind, HP; Johannessen, DC; Kriemler, HP; Lønning, PE; Miller, WR; Schneider, W; Waldmeier, F; Winkler, T	1
Coombes, RC; Ford, HT; Gazet, JC; Gray, R; Lowndes, S; Makinde, V; McConkey, C; Quilliam, J; Sutcliffe, R	1
Buzdar, A; Howell, A	1
Carlini, P; Casali, A; Cognetti, F; De Marco, S; Fabi, A; Frassoldati, A; Nardi, M; Paoloni, F; Papaldo, P; Ruggeri, EM	1
Lombardi, P	1
Christodoulides, A; Ghilchik, MW; Koistinen, R; Reed, MJ; Seppälä, M; Teale, JD	1
Borja, J; Pérez, N	1
Coombes, RC; Dowsett, M; Stein, RC	1
Dowsett, M; Jacobs, S; Jones, AL; Lonning, PE; MacNeill, F; Powles, TJ	1
Coombes, RC; Dowsett, M; Hughes, SW	1
Dowsett, M; Ekse, D; Jacobs, S; Johannessen, DC; Jones, A; Lønning, PE; McNeil, F; Powles, TJ	1
James, VH; Purohit, A; Reed, MJ	1
Coombes, RC; Dowsett, M; King, N; Mehta, A; Powles, TJ; Smith, IE; Stein, RC	1
Coombes, RC; Ford, HT; Gazet, JC	1
Anderson, ED; Anderson, TJ; Chetty, U; Forrest, AP; Hawkins, RA; Leonard, RC	1
Dowsett, M; Firth, J; Jarman, M; Poon, GK; Rowlands, MG	1
Aherne, GW; Chakraborty, J; Ghilchik, MW; Patel, S; Reed, MJ	1
Brodie, A	1
Dowsett, M; Lønning, PE; Powles, TJ	1
Coldham, NG; Ghilchik, MW; James, VH; Lai, LC; Reed, MJ; Shaikh, NA	1
Coombes, RC; Dowsett, M; Ford, HT; Gazet, JC; Hedley, A; Stein, RC	1
Distler, W; von Matthiessen, H	1
Eidtmann, H; Jonat, W; Kügler, G; Kunz, T; Maass, H	1
Santen, RJ	1
Becher, R; Callies, R; Friederich, P; Höffken, K; Jonat, W; Kölbel, M; Kunz, T; Possinger, K; Wagner, H; Willmanns, W	1
Banks, PK; Brodie, AM; Coombes, RC; Dowsett, M; Inkster, SE	1
Banks, PK; Brodie, AM; Inkster, SE; Koos, RD; Son, C	1
Coldham, NG; Ghilchik, MW; James, VH; Lai, LC; Owen, AM; Purohit, A; Reed, MJ; Shaikh, NA; Singh, A	1
Coombes, RC; Davenport, J; Dowsett, M; Ford, HT; Gazet, JC; Hedley, A; Stein, RC	1
Murray, P; Perry, L; Pickles, T; Plowman, P	1
Henderson, D	1
Anderson, ED; Chetty, U; Forrest, AP; Hawkins, RA; Levack, PA	1
Miller, WR	1
Coldham, NG; Ghilchik, MW; James, VH; Lai, LC; Owen, AM; Reed, MJ; Shaikh, NA	1
Manni, A; Santen, RJ	1
Coombes, RC; Cunningham, DC; Dehennin, L; Dowsett, M; Evans, S; Hedley, A; Stein, RC	1
Brodie, AM; Coombes, RC; Dowsett, M; Gazet, JC; Goss, PE; Hutchison, G; Powles, TJ	1
Brandt, ME; Covey, DF; Fendl, K; Garola, R; Puett, D; Zimniski, SJ	1
Brodie, AM; Coombes, RC; Dowsett, M	1
Miller, WR; O'Neill, J	1
Feil, PD; Leszczynski, D; Manni, A; Santen, RJ; Santner, SJ; Tilson-Mallet, N; Wright, C	1
Brodie, AM; Coombes, RC; Cunningham, D; Dowsett, M; Ford, HT; Gazet, JC; Hutchison, G; Powles, TJ	1
Brodie, AM; Coombes, RC; Dowsett, M; Goss, P; Wing, LY	2
Coombes, RC; Easton, D; Goss, PE; Singh, D; Wilkinson, JR; Williams, JC	1

Reviews

48 review(s) available for formestane and Breast Cancer

Article	Year
Developing steroidal aromatase inhibitors-an effective armament to win the battle against breast cancer. European journal of medicinal chemistry, 2015, Nov-13, Volume: 105 Topics: Aromatase; Aromatase Inhibitors; Breast Neoplasms; Drug Design; Female; Humans; Models, Molecular; Molecular Structure	2015
An overview on Estrogen receptors signaling and its ligands in breast cancer. European journal of medicinal chemistry, 2022, Nov-05, Volume: 241 Topics: Breast Neoplasms; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Humans; Ligands; Male; Receptors, Estrogen	2022
[Progress in study of the structure, catalytic mechanism and inhibitors of aromatase]. Yao xue xue bao = Acta pharmaceutica Sinica, 2012, Volume: 47, Issue:1 Topics: Androstenedione; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Catalysis; Coumarins; Estrogens; Flavonoids; Humans; Inhibitory Concentration 50; Letrozole; Nitriles; Sesquiterpenes; Structure-Activity Relationship; Triazoles; Xanthones	2012
[Aromatase inhibitors in adjuvant setting in breast cancer]. Bulletin du cancer, 2004, Dec-01, Volume: 91 Suppl 4 Topics: Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Letrozole; Menopause; Nitriles; Triazoles	2004
New aromatase inhibitors as second-line endocrine therapy in postmenopausal patients with metastatic breast carcinoma: a pooled analysis of the randomized trials. Cancer, 2005, Oct-01, Volume: 104, Issue:7 Topics: Aged; Anastrozole; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Carcinoma; Clinical Trials, Phase III as Topic; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Fadrozole; Female; Humans; Letrozole; Middle Aged; Neoplasm Staging; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Probability; Prognosis; Remission Induction; Risk Assessment; Survival Analysis; Triazoles	2005
Survival with aromatase inhibitors and inactivators versus standard hormonal therapy in advanced breast cancer: meta-analysis. Journal of the National Cancer Institute, 2006, Sep-20, Volume: 98, Issue:18 Topics: Adult; Aged; Aminoglutethimide; Anastrozole; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Female; Humans; Letrozole; Middle Aged; Neoplasm Staging; Neoplasms, Hormone-Dependent; Nitriles; Odds Ratio; Randomized Controlled Trials as Topic; Survival Analysis; Triazoles	2006
Aromatase inhibitors: past, present and future in breast cancer therapy. Medical oncology (Northwood, London, England), 2008, Volume: 25, Issue:2 Topics: Aminoglutethimide; Androstadienes; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Fadrozole; Female; Humans; Letrozole; Nitriles; Triazoles	2008
Formestane. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the management of breast cancer and prostatic cancer. Drugs, 1993, Volume: 45, Issue:1 Topics: Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; In Vitro Techniques; Male; Prostatic Neoplasms	1993
Aromatase and its inhibitors in breast cancer treatment--overview and perspective. Breast cancer research and treatment, 1994, Volume: 30, Issue:1 Topics: Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Steroids	1994
The role of aromatase in breast tumors. Breast cancer research and treatment, 1994, Volume: 30, Issue:1 Topics: Androstenedione; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; DNA Polymerase II; Estrogens; Estrone; Female; Humans; Prognosis; Receptors, Progesterone; Tumor Cells, Cultured	1994
Second generation aromatase inhibitor--4-hydroxyandrostenedione. Breast cancer research and treatment, 1994, Volume: 30, Issue:1 Topics: Administration, Oral; Adult; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Female; Humans; Injections, Intramuscular; Male	1994
Aromatase, its inhibitors and their use in breast cancer treatment. Pharmacology & therapeutics, 1993, Volume: 60, Issue:3 Topics: Aminoglutethimide; Androstenedione; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Half-Life; Humans; Neoplasms, Hormone-Dependent; Pargyline	1993
Formestane for advanced breast cancer in postmenopausal women. Drug and therapeutics bulletin, 1993, Oct-25, Volume: 31, Issue:22 Topics: Androstenedione; Antineoplastic Agents; Breast Neoplasms; Costs and Cost Analysis; Female; Humans; Injections, Intramuscular; Postmenopause	1993
Experience with aromatase inhibitors in the treatment of advanced breast cancer. Cancer treatment reviews, 1993, Volume: 19 Suppl B Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Female; Forecasting; Humans	1993
The control and biological importance of intratumoural aromatase in breast cancer. The Journal of steroid biochemistry and molecular biology, 1996, Volume: 56, Issue:1-6 Spec N Topics: Adenocarcinoma; Androgens; Androstenedione; Animals; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Carcinoma; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Estrogens; Female; Humans; Letrozole; Male; Mice; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Nitriles; Triazoles; Tumor Cells, Cultured	1996
Formestane. A review of its pharmacological properties and clinical efficacy in the treatment of postmenopausal breast cancer. Drugs & aging, 1996, Volume: 9, Issue:4 Topics: Androstenedione; Animals; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Postmenopause; Rats	1996
Proper sequence of endocrine therapies in advanced breast cancer. Acta oncologica (Stockholm, Sweden), 1996, Volume: 35 Suppl 5 Topics: Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Postmenopause; Premenopause	1996
Use of aromatase inhibitors in postmenopausal women with advanced breast cancer. Journal of surgical oncology, 1997, Volume: 66, Issue:3 Topics: Aminoglutethimide; Anastrozole; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Estrogen Antagonists; Female; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Tamoxifen; Triazoles	1997
Pharmacological profiles of exemestane and formestane, steroidal aromatase inhibitors used for treatment of postmenopausal breast cancer. Breast cancer research and treatment, 1998, Volume: 49 Suppl 1 Topics: Androstadienes; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Neoplasms, Hormone-Dependent; Postmenopause	1998
Aromatase inhibitors and their use in the adjuvant setting. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1998, Volume: 152 Topics: Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Enzyme Inhibitors; Fadrozole; Female; Humans	1998
New aromatase inhibitors for the treatment of advanced breast cancer in postmenopausal women. The Netherlands journal of medicine, 1999, Volume: 55, Issue:2 Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Female; Humans; Letrozole; Megestrol Acetate; Nitriles; Postmenopause; Triazoles	1999
[Aromatase inhibitors]. Bulletin du cancer, 1999, Volume: 86, Issue:10 Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Estrogen Antagonists; Estrone; Female; Humans; Letrozole; Nitriles; Triazoles	1999
Aromatase inhibitors and their application in breast cancer treatment. Steroids, 2000, Volume: 65, Issue:4* Topics: Androstenedione; Animals; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estrogens; Female; Humans; Letrozole; Mice; Nitriles; Tamoxifen; Triazoles	2000
Drug and hormone interactions of aromatase inhibitors. Endocrine-related cancer, 1999, Volume: 6, Issue:2 Topics: Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Interactions; Enzyme Inhibitors; Estrogens; Fadrozole; Female; Humans; Letrozole; Male; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Premenopause; Sensitivity and Specificity; Tamoxifen; Triazoles	1999
Aromatase inhibitors and their use in the sequential setting. Endocrine-related cancer, 1999, Volume: 6, Issue:2 Topics: Androstenedione; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Triazoles	1999
Use of aromatase inhibitors in breast carcinoma. Endocrine-related cancer, 1999, Volume: 6, Issue:1 Topics: Adult; Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Drug Design; Drug Interactions; Drug Resistance, Neoplasm; Enzyme Inhibitors; Estrogens; Female; Humans; Letrozole; Middle Aged; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Premenopause; Tamoxifen; Triazoles	1999
Steroidal aromatase inhibitors in elderly patients. Critical reviews in oncology/hematology, 2000, Volume: 33, Issue:2 Topics: Aged; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Triazoles	2000
[Aromatase inhibitors: a review of clinical trials]. Bulletin du cancer, 2000, Volume: 87 Spec No Topics: Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Randomized Controlled Trials as Topic; Triazoles	2000
Advances in aromatase inhibition: clinical efficacy and tolerability in the treatment of breast cancer. Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:9 Topics: Anastrozole; Androstadienes; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Fadrozole; Female; Headache; Humans; Letrozole; Nausea; Nitriles; Treatment Outcome; Triazoles; Vomiting	2001
Exemestane, a new steroidal aromatase inhibitor of clinical relevance. Biochimica et biophysica acta, 2002, Jul-18, Volume: 1587, Issue:2-3 Topics: Androstadienes; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estrogen Receptor Modulators; Estrogens; Female; Humans; Neoplasms, Hormone-Dependent	2002
Aromatase inhibitors: clinical pharmacology and therapeutic implications in breast cancer. The Journal of international medical research, 1992, Volume: 20, Issue:4 Topics: Aminoglutethimide; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Female; Humans; Imidazoles; Letrozole; Nitriles; Triazoles	1992
Aromatization inhibition alone or in combination with GnRH agonists for the treatment of premenopausal breast cancer patients. The Journal of steroid biochemistry and molecular biology, 1992, Volume: 43, Issue:1-3 Topics: Androstenedione; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Buserelin; Estrogens; Female; Goserelin; Humans; Menopause	1992
Inhibition of oestrogen synthesis in postmenopausal women with breast cancer. The Journal of steroid biochemistry and molecular biology, 1992, Volume: 43, Issue:1-3 Topics: Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Arylsulfatases; Breast Neoplasms; Danazol; Estrogens; Female; Humans; Kinetics; Menopause; Steryl-Sulfatase	1992
Aromatase and its inhibitors--an overview. The Journal of steroid biochemistry and molecular biology, 1991, Volume: 40, Issue:1-3 Topics: Androstenedione; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Humans	1991
Postmenopausal estrogen synthesis and metabolism: alterations caused by aromatase inhibitors used for the treatment of breast cancer. Journal of steroid biochemistry, 1990, Volume: 35, Issue:3-4 Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Fadrozole; Female; Humans; Imidazoles; Menopause; Nitriles	1990
New trends in the endocrine treatment of breast cancer. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1990, Volume: 118 Topics: Androstenedione; Breast Neoplasms; Buserelin; Female; Goserelin; Humans; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen	1990
Recent progress in development of aromatase inhibitors. The Journal of steroid biochemistry and molecular biology, 1990, Dec-20, Volume: 37, Issue:6 Topics: Aminoglutethimide; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Fadrozole; Humans; Imidazoles; Nitriles	1990
Clinical development of aromatase inhibitors for the treatment of breast and prostate cancer. The Journal of steroid biochemistry and molecular biology, 1990, Dec-20, Volume: 37, Issue:6 Topics: Aminoglutethimide; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Design; Estrogen Antagonists; Fadrozole; Humans; Imidazoles; Nitriles	1990
Aromatase inhibitors and hormone-dependent cancers. The Journal of steroid biochemistry and molecular biology, 1990, Nov-20, Volume: 37, Issue:3 Topics: Androstenedione; Animals; Aromatase Inhibitors; Breast Neoplasms; Humans; Neoplasms, Hormone-Dependent	1990
Aromatase and other inhibitors in breast and prostatic cancer. The Journal of steroid biochemistry and molecular biology, 1990, Dec-20, Volume: 37, Issue:6 Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Estrogen Antagonists; Humans; Male; Prostatic Neoplasms	1990
Aromatase inhibitors: their biochemistry and clinical potential. Journal of steroid biochemistry, 1987, Volume: 27, Issue:4-6 Topics: 17-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androstenedione; Animals; Aromatase Inhibitors; Breast Neoplasms; Chemical Phenomena; Chemistry; Estrogens; Female; Humans; Male; Oxidoreductases; Prostatic Hyperplasia	1987
Aromatase inhibitors in the treatment of advanced breast cancer. Cancer treatment reviews, 1989, Volume: 16, Issue:2 Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Female; Humans; Imidazoles; Neoplasms, Hormone-Dependent; Nitriles	1989
Clinical use of aromatase inhibitors in the treatment of breast cancer. Cancer treatment and research, 1988, Volume: 39 Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Estrogen Antagonists; Estrogens; Female; Humans	1988
Aromatase in breast cancer and the role of aminoglutethimide and other aromatase inhibitors. Critical reviews in oncology/hematology, 1986, Volume: 5, Issue:4 Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Aged; Aminoglutethimide; Androgens; Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Estrogens; Female; Humans; Mammary Neoplasms, Experimental; Metabolic Clearance Rate; Middle Aged; Rats; Tamoxifen	1986
Aromatase and aromatase inhibitors: from enzymology to selective chemotherapy. Progress in clinical and biological research, 1988, Volume: 262 Topics: Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Neoplasms, Hormone-Dependent; Pargyline; Rats	1988
Aromatase inhibitors: basic and clinical studies. Journal of steroid biochemistry, 1987, Volume: 27, Issue:4-6 Topics: Androstenedione; Animals; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Female; Humans; In Vitro Techniques; Mammary Neoplasms, Experimental; Ovary	1987
Enzymatic control of estrogen production in human breast cancer: relative significance of aromatase versus sulfatase pathways. Annals of the New York Academy of Sciences, 1986, Volume: 464 Topics: 17-Hydroxysteroid Dehydrogenases; Adrenalectomy; Aminoglutethimide; Androstenedione; Animals; Aromatase; Breast Neoplasms; Estradiol; Estrogens; Estrone; Female; Humans; Hydrocortisone; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Sulfatases; Testolactone	1986
Aromatase inhibition and its pharmacologic implications. Biochemical pharmacology, 1985, Sep-15, Volume: 34, Issue:18 Topics: Androstatrienes; Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Female; Humans; Kinetics; Macaca mulatta; Male; Mammary Neoplasms, Experimental; Menopause; Oligospermia; Oxidoreductases; Rats; Uterine Neoplasms	1985

Trials

34 trial(s) available for formestane and Breast Cancer

Article	Year
[Clinical trial of lentaron for postmenopausal patients with advanced breast cancer]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 2002, Volume: 24, Issue:5 Topics: Androstenedione; Antineoplastic Agents; Breast Neoplasms; Disease Progression; Female; Humans; Neoplasm Metastasis; Neoplasm Staging; Postmenopause; Treatment Outcome	2002
Postmenopausal women who progress on fulvestrant ('Faslodex') remain sensitive to further endocrine therapy. Breast cancer research and treatment, 2003, Volume: 79, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Disease Progression; Double-Blind Method; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Inhibitors; Estradiol; Estrogen Receptor Modulators; Female; Follow-Up Studies; Fulvestrant; Humans; Letrozole; Megestrol Acetate; Middle Aged; Nitriles; Postmenopause; Retrospective Studies; Salvage Therapy; Treatment Outcome; Triazoles	2003
Is there a benefit by the sequence anastrozole-formestane for postmenopausal metastatic breast cancer women? The Journal of steroid biochemistry and molecular biology, 2003, Volume: 86, Issue:1 Topics: Adult; Aged; Anastrozole; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Drug Administration Schedule; Enzyme Inhibitors; Female; Humans; Middle Aged; Neoplasm Metastasis; Nitriles; Postmenopause; Receptors, Estrogen; Tamoxifen; Triazoles	2003
The estrogen suppression after sequential treatment with formestane in advanced breast cancer patients. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2004, Volume: 58, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Estrogen Antagonists; Female; Humans; Injections, Intramuscular; Middle Aged; Postmenopause; Receptors, Estradiol	2004
Aromatase inhibition with 4-OHAndrostenedione after prior aromatase inhibition with aminoglutethimide in women with advanced breast cancer. Breast cancer research and treatment, 1995, Volume: 35, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Aminoglutethimide; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; Female; Humans; Middle Aged; Neoplasm Staging; Ovariectomy; Postmenopause	1995
The effects of oral 4-hydroxyandrostenedione on peripheral aromatisation in post-menopausal breast cancer patients. Cancer chemotherapy and pharmacology, 1995, Volume: 36, Issue:3 Topics: Administration, Oral; Aged; Aged, 80 and over; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Dose-Response Relationship, Drug; Estradiol; Female; Humans; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Postmenopause	1995
Formestane: effective therapy in postmenopausal women with advanced breast cancer. Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5 Suppl 7 Topics: 17-Hydroxycorticosteroids; Aged; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; Estradiol; Female; Humans; Middle Aged; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Postmenopause; Receptors, Estrogen	1994
Comparison of the selective aromatase inhibitor formestane with tamoxifen as first-line hormonal therapy in postmenopausal women with advanced breast cancer. Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5 Suppl 7 Topics: Adult; Aged; Aged, 80 and over; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Middle Aged; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Postmenopause; Receptors, Estrogen; Survival Analysis; Tamoxifen	1994
Formestane in the treatment of advanced postmenopausal breast cancer. Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5 Suppl 7 Topics: Adult; Aged; Aged, 80 and over; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Female; Humans; Injections, Intramuscular; Middle Aged; Neoplasm Metastasis; Postmenopause; Remission Induction	1994
Formestane as treatment of advanced breast cancer in elderly women. Tumori, 1994, Dec-31, Volume: 80, Issue:6 Topics: Aged; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Prognosis; Risk Factors; Treatment Outcome	1994
Effect of two-4-hydroxyandrostenedione doses on serum insulin-like growth factor I levels in advanced breast cancer. Breast cancer research and treatment, 1994, Volume: 30, Issue:2 Topics: Aged; Androstenedione; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Insulin-Like Growth Factor I; Middle Aged; Neoplasm Metastasis; Postmenopause; Time Factors	1994
Endocrinological and clinical evaluation of two doses of formestane in advanced breast cancer. British journal of cancer, 1994, Volume: 70, Issue:1 Topics: 17-Hydroxycorticosteroids; Aged; Analysis of Variance; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chi-Square Distribution; Estradiol; Female; Humans; Hydrocortisone; Middle Aged; Receptors, Estrogen; Remission Induction; Treatment Outcome	1994
Treatment with formestane alone and in combination with aminoglutethimide in heavily pretreated breast cancer patients: clinical and endocrine effects. European journal of cancer (Oxford, England : 1990), 1996, Volume: 32A, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Aminoglutethimide; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Female; Humans; Middle Aged	1996
A multicentre, randomized, pharmacokinetic, endocrine and clinical study to evaluate formestane in breast cancer patients at first relapse: endocrine and clinical results. The Italian Trials in Medical Oncology (I.T.M.O.) group. Annals of oncology : official journal of the European Society for Medical Oncology, 1997, Volume: 8, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Estrone; Female; Humans; Injections, Intramuscular; Middle Aged; Postmenopause; Survival Analysis; Treatment Outcome	1997
Formestane versus megestrol acetate in postmenopausal breast cancer patients after failure of tamoxifen: a phase III prospective randomised cross over trial of second-line hormonal treatment (SAKK 20/90). Swiss Group for Clinical Cancer Research (SAKK) European journal of cancer (Oxford, England : 1990), 1997, Volume: 33, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Androstenedione; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cross-Over Studies; Female; Humans; Megestrol Acetate; Middle Aged; Neoplasm Metastasis; Postmenopause; Prospective Studies; Receptors, Estrogen; Regression Analysis; Remission Induction; Tamoxifen; Time Factors; Treatment Failure	1997
Primary systemic therapy for operable breast cancer--10-year survival data after chemotherapy and hormone therapy. British journal of cancer, 1997, Volume: 76, Issue:8 Topics: Adult; Aged; Aminoglutethimide; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Follow-Up Studies; Goserelin; Humans; Hydrocortisone; Lymphatic Metastasis; Middle Aged; Neoplasms, Hormone-Dependent; Ovariectomy; Prednisone; Preoperative Care; Tamoxifen; Treatment Outcome; Vincristine	1997
A randomised comparison of oestrogen suppression with anastrozole and formestane in postmenopausal patients with advanced breast cancer. Oncology, 1997, Volume: 54 Suppl 2 Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estradiol; Female; Humans; Middle Aged; Nitriles; Postmenopause; Treatment Outcome; Triazoles	1997
Anastrozole shows evidence of activity in postmenopausal patients who have responded or stabilised on formestane therapy. European journal of cancer (Oxford, England : 1990), 1999, Volume: 35, Issue:5 Topics: Anastrozole; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Disease Progression; Female; Humans; Nitriles; Postmenopause; Prospective Studies; Receptors, Estrogen; Treatment Outcome; Triazoles	1999
Vorozole results in greater oestrogen suppression than formestane in postmenopausal women and when added to goserelin in premenopausal women with advanced breast cancer. Breast cancer research and treatment, 1999, Volume: 56, Issue:1 Topics: Adult; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Estradiol; Female; Goserelin; Humans; Middle Aged; Ovary; Postmenopause; Premenopause; Triazoles	1999
Quality of life in postmenopausal patients with breast cancer after failure of tamoxifen: formestane versus megestrol acetate as second-line hormonal treatment. Swiss Group for Clinical Cancer Research (SAKK). European journal of cancer (Oxford, England : 1990), 1999, Volume: 35, Issue:6 Topics: Adaptation, Psychological; Adult; Aged; Aged, 80 and over; Androstenedione; Antineoplastic Agents; Breast Neoplasms; Female; Humans; Megestrol Acetate; Middle Aged; Quality of Life; Tamoxifen; Treatment Failure	1999
Defining clinical benefit in postmenopausal patients with breast cancer under second-line endocrine treatment: does quality of life matter? Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Androstenedione; Antineoplastic Agents; Breast Neoplasms; Disease-Free Survival; Female; Health Status; Humans; Megestrol Acetate; Middle Aged; Postmenopause; Quality of Life; Statistics as Topic; Treatment Outcome	1999
A randomized, open, parallel-group trial to compare the endocrine effects of oral anastrozole (Arimidex) with intramuscular formestane in postmenopausal women with advanced breast cancer. Annals of oncology : official journal of the European Society for Medical Oncology, 1999, Volume: 10, Issue:10 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anastrozole; Androstenedione; Antineoplastic Agents; Breast Neoplasms; Estrogens; Female; Humans; Injections, Intramuscular; Middle Aged; Nitriles; Triazoles	1999
The luteinising hormone-releasing hormone analogue triptorelin with or without the aromatase inhibitor formestane in premenopausal breast cancer: effects on bone metabolism markers. The Journal of steroid biochemistry and molecular biology, 2000, Dec-01, Volume: 75, Issue:1 Topics: Adult; Androstenedione; Aromatase Inhibitors; Biomarkers; Bone and Bones; Breast Neoplasms; Estradiol; Female; Gonadotropin-Releasing Hormone; Growth Substances; Humans; Interleukin-6; Middle Aged; Premenopause; Statistics, Nonparametric; Triptorelin Pamoate	2000
Estrogen-receptor-directed neoadjuvant therapy for breast cancer: results of a randomised trial using formestane and methotrexate, mitozantrone and mitomycin C (MMM) chemotherapy. Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:5 Topics: Adult; Aged; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Goserelin; Humans; Methotrexate; Middle Aged; Mitomycin; Mitoxantrone; Neoadjuvant Therapy; Neoplasm Metastasis; Postmenopause; Premenopause; Prognosis; Receptors, Estrogen; Survival Analysis	2001
4-hydroxyandrostenedione: a new treatment for postmenopausal patients with breast cancer. European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A, Issue:12 Topics: Adult; Aged; Aged, 80 and over; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Drug Evaluation; Estradiol; Female; Humans; Injections, Intramuscular; Menopause; Middle Aged; Time Factors	1992
Influence of aminoglutethimide on plasma oestrogen levels in breast cancer patients on 4-hydroxyandrostenedione treatment. Breast cancer research and treatment, 1992, Volume: 23, Issue:1-2 Topics: Adult; Aged; Aged, 80 and over; Aminoglutethimide; Androstenedione; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Female; Humans; Middle Aged; Pilot Projects	1992
An endocrine and pharmacokinetic study of four oral doses of formestane in postmenopausal breast cancer patients. European journal of cancer (Oxford, England : 1990), 1992, Volume: 28, Issue:2-3 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Androstenedione; Antineoplastic Agents; Breast Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Estradiol; Female; Humans; Menopause; Middle Aged	1992
Randomised trial of chemotherapy versus endocrine therapy in patients presenting with locally advanced breast cancer (a pilot study). British journal of cancer, 1991, Volume: 63, Issue:2 Topics: Adult; Aged; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Buserelin; Female; Goserelin; Humans; Immunohistochemistry; Middle Aged; Neoplasm Staging; Pilot Projects; Receptors, Estrogen	1991
Primary systemic therapy for operable breast cancer. British journal of cancer, 1991, Volume: 63, Issue:4 Topics: Adult; Aged; Aminoglutethimide; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Buserelin; Combined Modality Therapy; Female; Goserelin; Humans; Lymphatic Metastasis; Middle Aged; Ovariectomy; Tamoxifen	1991
The clinical and endocrine effects of 4-hydroxyandrostenedione alone and in combination with goserelin in premenopausal women with advanced breast cancer. British journal of cancer, 1990, Volume: 62, Issue:4 Topics: Adult; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Buserelin; Female; Goserelin; Humans; Menopause; Middle Aged; Ovariectomy	1990
New trends in the endocrine treatment of breast cancer. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1990, Volume: 118 Topics: Androstenedione; Breast Neoplasms; Buserelin; Female; Goserelin; Humans; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen	1990
Aromatase inhibition with 4-hydroxyandrostenedione in the treatment of postmenopausal patients with advanced breast cancer: a phase II study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1990, Volume: 8, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Evaluation; Estradiol; Female; Germany, West; Humans; Life Tables; Menopause; Middle Aged; Multicenter Studies as Topic; Receptors, Estrogen; Remission Induction; Tamoxifen	1990
Dose-related endocrine effects and pharmacokinetics of oral and intramuscular 4-hydroxyandrostenedione in postmenopausal breast cancer patients. Cancer research, 1989, Mar-01, Volume: 49, Issue:5 Topics: Administration, Oral; Androstenedione; Breast Neoplasms; Dose-Response Relationship, Drug; Estradiol; Estrone; Female; Half-Life; Humans; Injections, Intramuscular; Menopause; Sex Hormone-Binding Globulin	1989
Aromatase in breast cancer and the role of aminoglutethimide and other aromatase inhibitors. Critical reviews in oncology/hematology, 1986, Volume: 5, Issue:4 Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Aged; Aminoglutethimide; Androgens; Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Estrogens; Female; Humans; Mammary Neoplasms, Experimental; Metabolic Clearance Rate; Middle Aged; Rats; Tamoxifen	1986

Other Studies

69 other study(ies) available for formestane and Breast Cancer

Article	Year
An efficient steroid pharmacophore-based strategy to identify new aromatase inhibitors. European journal of medicinal chemistry, 2009, Volume: 44, Issue:10 Topics: Androstenedione; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Drug Design; Female; Humans; Models, Molecular; Placenta; Pregnancy; Structure-Activity Relationship	2009
Synthesis and bioconversions of formestane. Journal of natural products, 2013, Oct-25, Volume: 76, Issue:10 Topics: Androstenedione; Aromatase Inhibitors; Beauveria; Biotransformation; Breast Neoplasms; Female; Humans; Stereoisomerism; Testosterone	2013
Synthesis and anticancer cell potential of steroidal 16,17-seco-16,17a-dinitriles: identification of a selective inhibitor of hormone-independent breast cancer cells. Bioorganic & medicinal chemistry, 2015, Feb-15, Volume: 23, Issue:4 Topics: Antineoplastic Agents; Aromatase; Breast; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Estrogen Receptor alpha; Female; HeLa Cells; Humans; Male; Molecular Docking Simulation; Nitriles; Prostate; Prostatic Neoplasms; Steroids	2015
Androstane derivatives induce apoptotic death in MDA-MB-231 breast cancer cells. Bioorganic & medicinal chemistry, 2015, Nov-15, Volume: 23, Issue:22 Topics: Androstanes; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Caspase 3; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Female; HeLa Cells; HT29 Cells; Humans; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Structure-Activity Relationship	2015
Exploring new chemical functionalities to improve aromatase inhibition of steroids. Bioorganic & medicinal chemistry, 2016, 06-15, Volume: 24, Issue:12 Topics: Androstanes; Androstenedione; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Molecular Docking Simulation; Steroids; Structure-Activity Relationship	2016
Angela M. Hartley Brodie (1934-2017). Nature, 2017, 08-02, Volume: 548, Issue:7665 Topics: Androstadienes; Androstenedione; Aromatase Inhibitors; Benzimidazoles; Breast Neoplasms; Estrogens; Female; History, 20th Century; History, 21st Century; Humans; Male; Maryland; Prostatic Neoplasms	2017
The beneficial androgenic action of steroidal aromatase inactivators in estrogen-dependent breast cancer after failure of nonsteroidal drugs. Cell death & disease, 2019, 06-24, Volume: 10, Issue:7 Topics: Androgens; Androstenedione; Animals; Anthracenes; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Female; Humans; Male; Mammary Neoplasms, Animal; MCF-7 Cells; Piperidines; Prostate; Protein Binding; Rats; RNA, Small Interfering; Seminal Vesicles; Steroids	2019
Synthesis and evaluation of novel 4-amino-4,6-androstadiene-3,17-dione: an analog of formestane. Bioorganic & medicinal chemistry letters, 2008, Oct-15, Volume: 18, Issue:20 Topics: Androstadienes; Androstenedione; Antineoplastic Agents; Aromatase; Breast Neoplasms; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Design; Drug Screening Assays, Antitumor; Humans; Models, Chemical	2008
Combined inhibitory effect of formestane and herceptin on a subpopulation of CD44+/CD24low breast cancer cells. Cancer science, 2010, Volume: 101, Issue:7 Topics: Androstenedione; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase; Aromatase Inhibitors; Breast Neoplasms; CD24 Antigen; Cell Line, Tumor; DNA Primers; ErbB Receptors; Female; Humans; Hyaluronan Receptors; Receptor Cross-Talk; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Trastuzumab; Tumor Cells, Cultured	2010
Effect of antiestrogens and aromatase inhibitor on basal growth of the human breast cancer cell line MCF-7 in serum-free medium. The Journal of steroid biochemistry and molecular biology, 2003, Volume: 84, Issue:4 Topics: Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Blotting, Northern; Blotting, Western; Breast Neoplasms; Cell Division; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Modulators; Fulvestrant; Humans; Ligands; Membrane Proteins; Piperidines; Presenilin-2; Protein Binding; Receptors, Estrogen; RNA, Messenger; Tamoxifen; Time Factors; Tumor Cells, Cultured	2003
Aromatase inhibitors increase the sensitivity of human tumor cells to monocyte-mediated, antibody-dependent cellular cytotoxicity. American journal of surgery, 2005, Volume: 190, Issue:4 Topics: Androstenedione; Antibody-Dependent Cell Cytotoxicity; Aromatase Inhibitors; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Female; Humans; Monocytes; Mucin-1; Ovarian Neoplasms; Peptide Elongation Factor 1; Receptors, Estrogen	2005
Cyclooxygenase-2 directly regulates gene expression of P450 Cyp19 aromatase promoter regions pII, pI.3 and pI.7 and estradiol production in human breast tumor cells. Prostaglandins & other lipid mediators, 2006, Volume: 81, Issue:1-2 Topics: Androstenedione; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Celecoxib; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Estradiol; Female; Gene Expression Regulation, Enzymologic; Humans; Promoter Regions, Genetic; Pyrazoles; Sulfonamides	2006
Coadministration of the aromatase inhibitor formestane and an isopropanolic extract of black cohosh in a rat model of chemically induced mammary carcinoma. Planta medica, 2007, Volume: 73, Issue:4 Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstenedione; Animals; Antineoplastic Agents, Phytogenic; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Cimicifuga; Drug Therapy, Combination; Estradiol; Female; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley	2007
In vitro expansion of human breast cancer epithelial and mesenchymal stromal cells: optimization of a coculture model for personalized therapy approaches. Molecular cancer therapeutics, 2007, Volume: 6, Issue:12 Pt 1 Topics: Androstenedione; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aromatase; Aromatase Inhibitors; Base Sequence; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Coculture Techniques; Cryopreservation; DNA Primers; Epithelial Cells; Humans; Mesoderm; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stromal Cells; Trastuzumab	2007
4-Hydroxyandrostenedione in treatment of postmenopausal patients with advanced breast cancer. Lancet (London, England), 1984, Dec-01, Volume: 2, Issue:8414 Topics: Adult; Aged; Androstenedione; Animals; Bone Neoplasms; Breast Neoplasms; Castration; Estradiol; Female; Humans; Injections, Intramuscular; Menopause; Mice; Middle Aged	1984
Comparative studies of aromatase inhibitors in relation to the significance of estrogen synthesis in human mammary tumors. Cancer research, 1982, Volume: 42, Issue:8 Suppl Topics: Aminoglutethimide; Androgens; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Cyanoketone; Dehydroepiandrosterone; Estrogens; Female; Humans; Kinetics; Oxidoreductases; Receptors, Estrogen	1982
Biological significance of aromatase activity in human breast tumors. The Journal of clinical endocrinology and metabolism, 1983, Volume: 57, Issue:6 Topics: Aminoglutethimide; Androstenedione; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Estrone; Female; Humans; Oxidoreductases; Receptors, Estrogen; Receptors, Progesterone; Testolactone	1983
Overview of recent development of aromatase inhibitors. Cancer research, 1982, Volume: 42, Issue:8 Suppl Topics: Aminoglutethimide; Androstatrienes; Androstenedione; Animals; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; In Vitro Techniques; Macaca mulatta; Male; Oxidoreductases; Pregnancy; Rats	1982
A new hypothesis based on suicide substrate inhibitor studies for the mechanism of action of aromatase. Cancer research, 1982, Volume: 42, Issue:8 Suppl Topics: Androstadienes; Androstatrienes; Androstenedione; Androstenes; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Female; Humans; Kinetics; Microsomes; Oxidoreductases; Placenta; Pregnancy; Structure-Activity Relationship; Testolactone	1982
Comparative studies of aromatase inhibitors in cultured human breast cancer cells. Cancer research, 1982, Volume: 42, Issue:8 Suppl Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Cell Line; Dihydrotestosterone; Estradiol; Female; Humans; Oxidoreductases; Pargyline; Receptors, Estrogen; Receptors, Progesterone; Testolactone; Testosterone	1982
Effects of 4-hydroxy-4-androstene-3, 17-dione and 10-propargylestr-4-ene-3, 17-dione on the metabolism of androstenedione in human breast carcinoma and breast adipose tissues. Steroids, 1981, Volume: 38, Issue:4 Topics: Adipose Tissue; Androstenedione; Breast; Breast Neoplasms; Female; Humans; Kinetics; Pargyline	1981
Inhibition of androgen aromatization in human breast cancer. Journal of steroid biochemistry, 1980, Volume: 13, Issue:12 Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Carbon Radioisotopes; Estradiol; Estrone; Female; Humans; Kinetics; Microsomes; Oxidoreductases; Placenta; Pregnancy	1980
Progress in the treatment and palliation of advanced breast cancer. Symposium proceedings. Jerusalem, 1993. Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5 Suppl 7 Topics: Androstenedione; Animals; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Diphosphonates; Female; Humans; Palliative Care; Pamidronate	1994
Formestane: an effective first-line endocrine treatment for advanced breast cancer. Journal of cancer research and clinical oncology, 1995, Volume: 121, Issue:6 Topics: 17-Hydroxycorticosteroids; Aged; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Administration Schedule; Estradiol; Female; Humans; Injections, Intramuscular; Middle Aged; Postmenopause; Prognosis; Risk Factors; Survival Analysis; Treatment Outcome	1995
Treatment of advanced breast cancer with formestane. Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5 Suppl 7 Topics: Adult; Aged; Aged, 80 and over; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Middle Aged; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Receptors, Estrogen; Remission Induction; Survival Analysis	1994
Aromatase inhibition: basic concepts, and the pharmacodynamics of formestane. Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5 Suppl 7 Topics: Androstenedione; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Postmenopause	1994
Analysis of the aromatase cytochrome P450 gene in human breast cancers. Journal of molecular endocrinology, 1994, Volume: 13, Issue:3 Topics: Androstenedione; Aromatase; Aromatase Inhibitors; Base Sequence; Breast Neoplasms; Cloning, Molecular; DNA Mutational Analysis; DNA Probes; Estradiol; Exons; Female; Humans; In Vitro Techniques; Molecular Sequence Data; Placenta; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational	1994
Plasma and urinary oestrogens in breast cancer patients on treatment with 4-hydroxyandrostenedione. British journal of cancer, 1993, Volume: 68, Issue:2 Topics: Aged; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Female; Humans; Male; Menopause; Middle Aged	1993
Combined treatment with 4-hydroxyandrostenedione and aminoglutethimide: effects on aromatase inhibition and oestrogen suppression. British journal of cancer, 1994, Volume: 69, Issue:6 Topics: Adult; Aged; Aminoglutethimide; Androstenedione; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Carbon Radioisotopes; Estrogens; Female; Humans; Middle Aged; Postmenopause; Radioisotope Dilution Technique	1994
Growth suppression of MCF-7 human breast cancer cells by aromatase inhibitors: a new system for aromatase inhibitor screening. The Journal of steroid biochemistry and molecular biology, 1993, Volume: 44, Issue:4-6 Topics: Aminoglutethimide; Androstenedione; Androstenols; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Division; Dose-Response Relationship, Drug; Fadrozole; Female; Humans; Kinetics; Tumor Cells, Cultured	1993
MCF-7 human breast carcinomas in nude mice as a model for evaluating aromatase inhibitors. The Journal of steroid biochemistry and molecular biology, 1993, Volume: 44, Issue:4-6 Topics: Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Cell Division; Female; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Tamoxifen; Transplantation, Heterologous; Tumor Cells, Cultured	1993
Efficacy and tolerability of 4-hydroxyandrostenedione (4-OHA) as first-line treatment in postmenopausal patients with breast cancer after adjuvant therapy. Cancer treatment reviews, 1993, Volume: 19 Suppl B Topics: Aged; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Menopause; Methotrexate; Middle Aged; Remission Induction; Tamoxifen; Treatment Outcome	1993
A sensitive assay for measurement of plasma estrone sulphate in patients on treatment with aromatase inhibitors. The Journal of steroid biochemistry and molecular biology, 1995, Volume: 55, Issue:3-4 Topics: Aminoglutethimide; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estrone; Female; Humans; Hydrolysis; Menopause; Radioimmunoassay; Sensitivity and Specificity	1995
Assesssment of the effect of pretreatment with neoadjuvant therapy on primary breast cancer. British journal of cancer, 1996, Volume: 73, Issue:6 Topics: Adult; Aged; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Female; Goserelin; Humans; Immunohistochemistry; Methotrexate; Middle Aged; Mitomycin; Mitoxantrone; Neoplasms, Hormone-Dependent; Receptors, Estrogen	1996
Oestrogen formation in breast: clinical and biological importance. The Journal of endocrinology, 1996, Volume: 150 Suppl Topics: Androstenedione; Animals; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast; Breast Neoplasms; Estrogens; Female; Humans; Letrozole; Mice; Mice, Nude; Nitriles; Signal Transduction; Transfection; Triazoles; Tumor Cells, Cultured	1996
Effects of treatment with megestrol acetate, aminoglutethimide, or formestane on insulin-like growth factor (IGF) I and II, IGF-binding proteins (IGFBPs), and IGFBP-3 protease status in patients with advanced breast cancer. The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:6 Topics: Aged; Aged, 80 and over; Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Blotting, Western; Breast Neoplasms; Endopeptidases; Female; Humans; Insulin-Like Growth Factor Binding Proteins; Megestrol Acetate; Middle Aged; Radioimmunoassay; Somatomedins	1996
Hypoglycaemia associated with formestane treatment. BMJ (Clinical research ed.), 1997, Mar-22, Volume: 314, Issue:7084 Topics: Androstenedione; Antineoplastic Agents; Breast Neoplasms; Diabetes Complications; Female; Humans; Hypoglycemia; Middle Aged	1997
Serum markers of bone metastases in postmenopausal breast cancer patients treated with formestane. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 1997, Volume: 18, Issue:4 Topics: Alkaline Phosphatase; Androstenedione; Antineoplastic Agents; Biomarkers, Tumor; Bone Neoplasms; Breast Neoplasms; Calcium-Binding Proteins; Extracellular Matrix Proteins; Female; Humans; Matrix Gla Protein; Peptide Fragments; Postmenopause; Procollagen	1997
Aromatase inhibitors come of age. Annals of oncology : official journal of the European Society for Medical Oncology, 1997, Volume: 8, Issue:7 Topics: Aminoglutethimide; Anastrozole; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase III as Topic; Female; Humans; Letrozole; Nitriles; Triazoles	1997
Aromatase inhibitors for breast cancer--further progress. European journal of cancer (Oxford, England : 1990), 1997, Volume: 33, Issue:7 Topics: Aminoglutethimide; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Megestrol Acetate	1997
Tamoxifen-resistant fibroblast growth factor-transfected MCF-7 cells are cross-resistant in vivo to the antiestrogen ICI 182,780 and two aromatase inhibitors. Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:3 Topics: Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Cell Division; Cell Line; Chloramphenicol O-Acetyltransferase; Drug Resistance, Neoplasm; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Fibroblast Growth Factors; Fulvestrant; Humans; Letrozole; Luciferases; Mice; Mice, Nude; Nitriles; Ovariectomy; Polymerase Chain Reaction; Receptors, Progesterone; Recombinant Fusion Proteins; RNA, Messenger; Tamoxifen; Transcription, Genetic; Transfection; Transplantation, Heterologous; Triazoles; Tumor Cells, Cultured	1998
Severe immune thrombocytopenia during formestane treatment. Haematologica, 1998, Volume: 83, Issue:10 Topics: Androstenedione; Antineoplastic Agents; Breast Neoplasms; Female; Humans; Middle Aged; Neoplasm Metastasis; Postmenopause; Thrombocytopenia	1998
The steroidal antiestrogen ICI 182,780 is an inhibitor of cellular aromatase activity. The Journal of steroid biochemistry and molecular biology, 1998, Volume: 67, Issue:4 Topics: Anastrozole; Androstenedione; Aromatase; Aromatase Inhibitors; Base Sequence; Breast Neoplasms; Cell Division; Cells, Cultured; Choriocarcinoma; DNA Primers; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Fibroblasts; Fulvestrant; Humans; Letrozole; Microsomes; Nitriles; Placenta; RNA, Messenger; Triazoles; Tumor Cells, Cultured	1998
Influence of aromatase inhibitors on plasma total homocysteine in postmenopausal breast cancer patients. Clinical chemistry, 1999, Volume: 45, Issue:2 Topics: Aminoglutethimide; Androstadienes; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Creatinine; Enzyme Inhibitors; Estrogen Antagonists; Homocysteine; Humans; Postmenopause; Vitamins	1999
[Carcinomatous meningitis secondary to breast cancer. Spectacular response to hormone therapy]. Presse medicale (Paris, France : 1983), 1999, Jan-16, Volume: 28, Issue:2 Topics: Aged; Androstenedione; Antineoplastic Agents; Breast Neoplasms; Female; Humans; Mastectomy; Meningeal Neoplasms; Remission Induction; Tamoxifen; Treatment Outcome	1999
The aromatase inactivator 4-hydroxyandrostenedione (4-OH-A) inhibits tamoxifen metabolism by rat hepatic cytochrome P-450 3A: potential for drug-drug interaction of tamoxifen and 4-OH-A in combined anti-breast cancer therapy. Drug metabolism and disposition: the biological fate of chemicals, 1999, Volume: 27, Issue:3 Topics: Androstenedione; Animals; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase; Aromatase Inhibitors; Aryl Hydrocarbon Hydroxylases; Breast Neoplasms; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Activation; Liver; Male; Oxidoreductases, N-Demethylating; Rats; Rats, Sprague-Dawley; Tamoxifen	1999
Pilot study of formestane in postmenopausal women with breast cancer. The Medical journal of Malaysia, 1998, Volume: 53, Issue:1 Topics: Aged; Aged, 80 and over; Androstenedione; Antineoplastic Agents; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Middle Aged; Pilot Projects; Postmenopause	1998
Formestane is feasible and effective in elderly breast cancer patients with comorbidity and disability. Breast cancer research and treatment, 2000, Volume: 62, Issue:3 Topics: Activities of Daily Living; Aged; Aged, 80 and over; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Cardiovascular Diseases; Comorbidity; Enzyme Inhibitors; Female; Geriatric Assessment; Humans; Injections, Intramuscular; Treatment Outcome	2000
Dehydroepiandrosterone stimulates proliferation and gene expression in MCF-7 cells after conversion to estradiol. Molecular and cellular endocrinology, 2001, Feb-28, Volume: 173, Issue:1-2 Topics: Androstenedione; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Division; Chromatography, Thin Layer; Dehydroepiandrosterone; Dexamethasone; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Immunoassay; Mitogens; Tamoxifen; Transcriptional Activation; Transfection; Tumor Cells, Cultured	2001
Pharmacokinetics and metabolism of formestane in breast cancer patients. The Journal of steroid biochemistry and molecular biology, 2001, Volume: 77, Issue:1 Topics: Aged; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Biological Availability; Biotransformation; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Middle Aged	2001
Formestane, a steroidal aromatase inhibitor after failure of non-steroidal aromatase inhibitors (anastrozole and letrozole): is a clinical benefit still achievable? Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:11 Topics: Adult; Aged; Anastrozole; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Disease Progression; Enzyme Inhibitors; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Receptors, Estrogen; Retrospective Studies; Treatment Failure; Triazoles	2001
The effect of endocrine therapy with medroxyprogesterone acetate, 4-hydroxyandrostenedione or tamoxifen on plasma concentrations of insulin-like growth factor (IGF)-I, IGF-II and IGFBP-1 in women with advanced breast cancer. International journal of cancer, 1992, Sep-09, Volume: 52, Issue:2 Topics: Aged; Androstenedione; Breast Neoplasms; Carrier Proteins; Female; Humans; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Medroxyprogesterone; Medroxyprogesterone Acetate; Neoplasms, Hormone-Dependent; Tamoxifen	1992
The influence of intramuscular 4-hydroxyandrostenedione on peripheral aromatisation in breast cancer patients. European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A, Issue:10 Topics: Aged; Aged, 80 and over; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Dose-Response Relationship, Drug; Estradiol; Estriol; Estrone; Female; Humans; Injections, Intramuscular; Middle Aged	1992
4-Hydroxyandrostenedione treatment for postmenopausal patients with breast cancer. The Journal of steroid biochemistry and molecular biology, 1992, Volume: 43, Issue:1-3 Topics: Adult; Aged; Aged, 80 and over; Androstenedione; Antineoplastic Agents; Breast Neoplasms; Dose-Response Relationship, Drug; Estradiol; Female; Humans; Menopause; Middle Aged	1992
Determination of 4-hydroxyandrost-4-ene-3,17-dione metabolism in breast cancer patients using high-performance liquid chromatography-mass spectrometry. Journal of chromatography, 1991, Apr-19, Volume: 565, Issue:1-2 Topics: Administration, Oral; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Chromatography, High Pressure Liquid; Female; Humans; Mass Spectrometry	1991
Concentrations of oestrone and 4-hydroxyandrostenedione in malignant and normal breast tissues. International journal of cancer, 1991, Oct-21, Volume: 49, Issue:4 Topics: Aged; Androstenedione; Aromatase Inhibitors; Breast; Breast Neoplasms; DNA Polymerase II; Estrone; Female; Humans; Neoplasm Staging	1991
Analysis by DNA polymerase alpha activity of human breast tumour proliferation and the effect of endocrine therapy. British journal of cancer, 1990, Volume: 62, Issue:2 Topics: Androstenedione; Antineoplastic Agents; Biopsy; Breast Neoplasms; DNA Polymerase II; Estrogens; Female; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Neoplasms, Hormone-Dependent; Receptors, Estrogen	1990
Endocrine and clinical aspects of new compounds for treatment of hormone-related cancer in gynecology. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1990, Volume: 118 Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Buserelin; Female; Goserelin; Humans; Neoplasms, Hormone-Dependent; Tamoxifen	1990
Effect of treatment with 4-hydroxyandrostenedione on the peripheral conversion of androstenedione to estrone and in vitro tumor aromatase activity in postmenopausal women with breast cancer. Cancer research, 1990, Jan-01, Volume: 50, Issue:1 Topics: Aged; Androstenedione; Antineoplastic Agents; Aromatase; Breast Neoplasms; DNA Polymerase II; Estrone; Female; Humans; Kinetics; Metabolic Clearance Rate	1990
Treatment of advanced breast cancer in postmenopausal women with 4-hydroxyandrostenedione. Cancer chemotherapy and pharmacology, 1990, Volume: 26, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Androstenedione; Antineoplastic Agents; Breast Neoplasms; Drug Evaluation; Estradiol; Female; Humans; Menopause; Middle Aged	1990
4-hydroxyandrostenedione--further clinical and extended endocrine observations. British journal of cancer, 1990, Volume: 62, Issue:2 Topics: Aged; Aged, 80 and over; Androstenedione; Antineoplastic Agents; Breast Neoplasms; Endocrine Glands; Female; Humans; Menopause; Middle Aged	1990
Response to endocrine manipulation and oestrogen receptor concentration in large operable primary breast cancer. British journal of cancer, 1989, Volume: 60, Issue:2 Topics: Aminoglutethimide; Androstenedione; Breast Neoplasms; Buserelin; Female; Goserelin; Humans; Menopause; Receptors, Estrogen; Tamoxifen	1989
In situ oestrone synthesis in normal breast and breast tumour tissues: effect of treatment with 4-hydroxyandrostenedione. International journal of cancer, 1989, Aug-15, Volume: 44, Issue:2 Topics: Aged; Androstenedione; Aromatase; Breast; Breast Neoplasms; DNA Polymerase II; Estrone; Female; Humans; Middle Aged	1989
Treatment of advanced postmenopausal breast cancer with an aromatase inhibitor, 4-hydroxyandrostenedione: phase II report. Cancer research, 1986, Volume: 46, Issue:9 Topics: Adult; Aged; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Dehydroepiandrosterone; Drug Evaluation; Estradiol; Estrone; Female; Humans; Menopause; Middle Aged; Sex Hormone-Binding Globulin	1986
Mammary steroidogenesis: therapeutic implications. International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1987, Volume: 14, Issue:4 Topics: 17-Hydroxysteroid Dehydrogenases; Adipose Tissue; Aminoglutethimide; Androstenedione; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Female; Humans; In Vitro Techniques	1987
Oral 4-hydroxyandrostenedione, a new endocrine treatment for disseminated breast cancer. Cancer chemotherapy and pharmacology, 1987, Volume: 20, Issue:3 Topics: Administration, Oral; Adult; Aged; Androstenedione; Breast Neoplasms; Estradiol; Female; Humans; Menopause; Middle Aged; Neoplasm Metastasis; Ovariectomy	1987
Aromatase inhibitors and the treatment of breast cancer. Journal of steroid biochemistry, 1986, Volume: 24, Issue:1 Topics: Adult; Aged; Aminoglutethimide; Androstenedione; Animals; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Female; Humans; Kinetics; Luteinizing Hormone; Macaca mulatta; Mammary Neoplasms, Experimental; Menopause; Middle Aged; Neoplasms, Hormone-Dependent; Ovary; Rats; Tamoxifen	1986
Response of nitrosomethylurea-induced rat mammary tumor to endocrine therapy and comparison with clinical response. Cancer research, 1986, Volume: 46, Issue:9 Topics: Aminoglutethimide; Androstenedione; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Danazol; Dihydrotestosterone; Female; Humans; Mammary Neoplasms, Experimental; Menopause; Methylnitrosourea; Ovariectomy; Rats; Tamoxifen	1986
Aromatase inhibitors and their potential clinical significance. Journal of steroid biochemistry, 1986, Volume: 25, Issue:5B Topics: Androstenedione; Animals; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Female; Humans; Menopause; Ovary; Rats	1986