Page last updated: 2024-10-18

formaldehyde and Xeroderma Pigmentosum

formaldehyde has been researched along with Xeroderma Pigmentosum in 4 studies

paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy

Xeroderma Pigmentosum: A rare, pigmentary, and atrophic autosomal recessive disease. It is manifested as an extreme photosensitivity to ULTRAVIOLET RAYS as the result of a deficiency in the enzyme that permits excisional repair of ultraviolet-damaged DNA.

Research Excerpts

ExcerptRelevanceReference
"The survival of excision-deficient and of excision-proficient (variant) skin fibroblasts from xeroderma pigmentosum (XP) donors was about 5 times and twice, respectively, more sensitive to formaldehyde (FA) treatment than that of skin fibroblasts from healthy and XP heterozygote donors."7.66Survival and herpes virus production of normal and xeroderma pigmentosum fibroblasts after treatment with formaldehyde. ( Coppey, J; Nocentini, S, 1979)
"The alkaline elution technique was used to study repair of DNA damage caused by formaldehyde (HCHO) in human bronchial epithelial cells and fibroblasts, skin fibroblasts, and DNA excision repair-deficient skin fibroblasts from donors with xeroderma pigmentosum."3.67Repair of DNA damage caused by formaldehyde in human cells. ( Fornace, A; Grafstrom, RC; Harris, CC, 1984)
"The survival of excision-deficient and of excision-proficient (variant) skin fibroblasts from xeroderma pigmentosum (XP) donors was about 5 times and twice, respectively, more sensitive to formaldehyde (FA) treatment than that of skin fibroblasts from healthy and XP heterozygote donors."3.66Survival and herpes virus production of normal and xeroderma pigmentosum fibroblasts after treatment with formaldehyde. ( Coppey, J; Nocentini, S, 1979)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Grafstrom, RC1
Fornace, A1
Harris, CC1
Speit, G1
Schütz, P1
Merk, O1
Quievryn, G1
Zhitkovich, A1
Coppey, J1
Nocentini, S1

Other Studies

4 other studies available for formaldehyde and Xeroderma Pigmentosum

ArticleYear
Repair of DNA damage caused by formaldehyde in human cells.
    Cancer research, 1984, Volume: 44, Issue:10

    Topics: Animals; Bronchi; Cell Line; DNA Repair; Epithelium; Fibroblasts; Formaldehyde; Humans; Kinetics; Le

1984
Induction and repair of formaldehyde-induced DNA-protein crosslinks in repair-deficient human cell lines.
    Mutagenesis, 2000, Volume: 15, Issue:1

    Topics: Cell Line; Cross-Linking Reagents; DNA; DNA Repair; Fanconi Anemia; Formaldehyde; Humans; Micronucle

2000
Loss of DNA-protein crosslinks from formaldehyde-exposed cells occurs through spontaneous hydrolysis and an active repair process linked to proteosome function.
    Carcinogenesis, 2000, Volume: 21, Issue:8

    Topics: Acetylcysteine; Animals; Cattle; Cell Line; Cysteine Proteinase Inhibitors; DNA; DNA Adducts; DNA Da

2000
Survival and herpes virus production of normal and xeroderma pigmentosum fibroblasts after treatment with formaldehyde.
    Mutation research, 1979, Volume: 62, Issue:2

    Topics: Cell Line; Cells, Cultured; DNA Repair; Formaldehyde; Humans; Phenotype; Simplexvirus; Skin; Virus R

1979