formaldehyde has been researched along with Squamous Cell Carcinoma of Head and Neck in 12 studies
paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy
Squamous Cell Carcinoma of Head and Neck: The most common type of head and neck carcinoma that originates from cells on the surface of the NASAL CAVITY; MOUTH; PARANASAL SINUSES, SALIVARY GLANDS, and LARYNX. Mutations in TNFRSF10B, PTEN, and ING1 genes are associated with this cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In formalin-fixed paraffin-embedded HNSCCs, NRF2 signaling intensity positively correlated with NRF2-activating mutations and with SOX2 protein expression." | 1.91 | Targeted Proteomic Quantitation of NRF2 Signaling and Predictive Biomarkers in HNSCC. ( Gerndt, SP; Gilmore, PE; Goldfarb, D; Guan, L; Holmes, BJ; Jackson, RS; LaPak, KM; Le, QT; Major, MB; Paniello, RC; Pipkorn, P; Puram, SV; Rich, JT; Schrank, TP; Sprung, RW; Townsend, RR; Wamsley, NT; Wilkerson, EM; Zevallos, JP; Zolkind, P, 2023) |
| "To determine genomic alterations in head and neck squamous cell carcinoma (HNSCC) using formalin-fixed, paraffin-embedded (FFPE) tumors obtained through routine clinical practice, selected cancer-related genes were evaluated and compared with alterations seen in frozen tumors obtained through research studies." | 1.42 | Genomic alterations in head and neck squamous cell carcinoma determined by cancer gene-targeted sequencing. ( Agrawal, N; Ali, SM; Bishop, JA; Chalmers, ZR; Chung, CH; Fakhry, C; Frampton, GM; Guthrie, VB; Kang, H; Karchin, R; Masica, DL; Miller, VA; Quon, H; Richmon, J; Seiwert, T; Stephens, PJ; Subramaniam, RM; Tokheim, C; Yelensky, R; Zuo, Z, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (50.00) | 24.3611 |
| 2020's | 6 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kamat, MS | 1 |
| Puranik, RS | 1 |
| Das Rai, AB | 1 |
| Patil, BR | 1 |
| Patil, S | 1 |
| Dressler, FF | 1 |
| Dabadghao, DS | 1 |
| Klapper, L | 1 |
| Perner, S | 1 |
| Idel, C | 1 |
| Ribbat-Idel, J | 1 |
| Wamsley, NT | 1 |
| Wilkerson, EM | 1 |
| Guan, L | 1 |
| LaPak, KM | 1 |
| Schrank, TP | 1 |
| Holmes, BJ | 1 |
| Sprung, RW | 1 |
| Gilmore, PE | 1 |
| Gerndt, SP | 1 |
| Jackson, RS | 1 |
| Paniello, RC | 1 |
| Pipkorn, P | 1 |
| Puram, SV | 1 |
| Rich, JT | 1 |
| Townsend, RR | 1 |
| Zevallos, JP | 1 |
| Zolkind, P | 1 |
| Le, QT | 1 |
| Goldfarb, D | 1 |
| Major, MB | 1 |
| Kapoor, S | 1 |
| Lu, G | 1 |
| van den Berg, NS | 1 |
| Krishnan, G | 1 |
| Pei, J | 1 |
| Zhou, Q | 1 |
| Martin, BA | 1 |
| Baik, FM | 1 |
| Rosenthal, EL | 1 |
| Nishio, N | 1 |
| Zhou, W | 1 |
| Rowe, L | 1 |
| Witt, B | 1 |
| Deftereos, G | 1 |
| Stepp, WH | 1 |
| Huho, AN | 1 |
| Yadak, N | 1 |
| Bocklage, TJ | 1 |
| Yang, S | 1 |
| Guo, M | 1 |
| Khanna, A | 1 |
| Wang, J | 1 |
| Williams, MD | 1 |
| Kalhor, N | 1 |
| Gong, Y | 1 |
| Xu, L | 1 |
| Sturgis, EM | 1 |
| Staerkel, G | 1 |
| Mori, T | 1 |
| Kobayashi, K | 1 |
| Yoshimoto, S | 1 |
| Chung, CH | 1 |
| Guthrie, VB | 1 |
| Masica, DL | 1 |
| Tokheim, C | 1 |
| Kang, H | 1 |
| Richmon, J | 1 |
| Agrawal, N | 1 |
| Fakhry, C | 1 |
| Quon, H | 1 |
| Subramaniam, RM | 1 |
| Zuo, Z | 1 |
| Seiwert, T | 1 |
| Chalmers, ZR | 1 |
| Frampton, GM | 1 |
| Ali, SM | 1 |
| Yelensky, R | 1 |
| Stephens, PJ | 1 |
| Miller, VA | 1 |
| Karchin, R | 1 |
| Bishop, JA | 1 |
| Rebelatto, MC | 1 |
| Midha, A | 1 |
| Mistry, A | 1 |
| Sabalos, C | 1 |
| Schechter, N | 1 |
| Li, X | 1 |
| Jin, X | 1 |
| Steele, KE | 1 |
| Robbins, PB | 1 |
| Blake-Haskins, JA | 1 |
| Walker, J | 1 |
| Mendez-Pena, JE | 1 |
| Sadow, PM | 1 |
| Nose, V | 1 |
| Hoang, MP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase I, Open-label Study Evaluating the Safety and Pharmacokinetics of Escalating Doses of Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Head and Neck Cancer During Surgical Procedures[NCT02415881] | Phase 1 | 64 participants (Actual) | Interventional | 2016-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for formaldehyde and Squamous Cell Carcinoma of Head and Neck
| Article | Year |
|---|---|
Development of a programmed cell death ligand-1 immunohistochemical assay validated for analysis of non-small cell lung cancer and head and neck squamous cell carcinoma.
Topics: Algorithms; Antibodies, Monoclonal; Antineoplastic Agents; Area Under Curve; B7-H1 Antigen; Biomarke | 2016 |
11 other studies available for formaldehyde and Squamous Cell Carcinoma of Head and Neck
| Article | Year |
|---|---|
Assessing immuno-expression of p53 protein and TP 53 gene amplification in histologically negative surgical margins of oral squamous cell carcinoma patients and normal oral mucosa.
Topics: Biomarkers, Tumor; Carcinoma, Squamous Cell; Formaldehyde; Gene Amplification; Head and Neck Neoplas | 2022 |
Deglycosylation of pathological specimens alters performance of diagnostic PDL1 antibodies.
Topics: Antibodies; B7-H1 Antigen; Formaldehyde; Head and Neck Neoplasms; Humans; Immune Checkpoint Inhibito | 2022 |
Targeted Proteomic Quantitation of NRF2 Signaling and Predictive Biomarkers in HNSCC.
Topics: Biomarkers, Tumor; Carcinoma, Squamous Cell; Cyclin-Dependent Kinase Inhibitor p16; Formaldehyde; He | 2023 |
Effect of Formalin Fixation for Near-Infrared Fluorescence Imaging with an Antibody-Dye Conjugate in Head and Neck Cancer Patients.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Immunological; Benzenesulfonates; ErbB Receptors; Fe | 2021 |
Application of the Roche Cobas® HPV 4800 in Formalin-Fixed, Paraffin-Embedded Samples for Head and Neck Squamous Cell Carcinomas.
Topics: Formaldehyde; Human Papillomavirus DNA Tests; Humans; Nucleic Acid Amplification Techniques; Papillo | 2021 |
High-Throughput NanoString Analysis of Oncogenic Human Papillomavirus and Tumor Microenvironment Transcription in Head and Neck Squamous Cell Carcinoma.
Topics: Fluorometry; Formaldehyde; Gene Expression Regulation, Viral; Head and Neck Neoplasms; High-Throughp | 2021 |
Evaluation of Diagnostic Utility of a High-Risk Human Papillomavirus PCR Test on Formalin-Fixed, Paraffin-Embedded Head and Neck Tumor Tissues.
Topics: Aged; Biomarkers, Tumor; Biopsy, Fine-Needle; Cyclin-Dependent Kinase Inhibitor p16; DNA, Viral; Fea | 2018 |
Incorporation of Cervista Human Papillomavirus 16/18 Assay Into Algorithms for Classifying Human Papillomavirus Status in Formalin-Fixed, Paraffin-Embedded Head and Neck Squamous Carcinoma Specimens.
Topics: Adult; Algorithms; Female; Formaldehyde; Human papillomavirus 16; Human papillomavirus 18; Humans; I | 2019 |
ASO Author Reflections: Precise p53 Analysis in Formalin-Fixed Paraffin-Embedded Specimens Can Predict Head and Neck Squamous Cell Carcinoma Outcomes.
Topics: Exons; Formaldehyde; Head and Neck Neoplasms; Humans; Paraffin Embedding; Phenotype; Squamous Cell C | 2019 |
Genomic alterations in head and neck squamous cell carcinoma determined by cancer gene-targeted sequencing.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cyclin-Dependent Kinase | 2015 |
RNA chromogenic in situ hybridization assay with clinical automated platform is a sensitive method in detecting high-risk human papillomavirus in squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Automation, Laboratory; Biomarkers, Tumor; Biopsy; Carcinoma, Squamo | 2017 |