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formaldehyde and Respiratory Syncytial Virus Infections

formaldehyde has been researched along with Respiratory Syncytial Virus Infections in 34 studies

paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy

Respiratory Syncytial Virus Infections: Pneumovirus infections caused by the RESPIRATORY SYNCYTIAL VIRUSES. Humans and cattle are most affected but infections in goats and sheep have been reported.

Research Excerpts

ExcerptRelevanceReference
" We evaluated the impact of TLR and Notch signaling on ERD in a murine model by administering CpG, an agonist of TLR9, in combination with L685,458, an inhibitor of Notch signaling during FI-RSV immunization."1.46CpG in Combination with an Inhibitor of Notch Signaling Suppresses Formalin-Inactivated Respiratory Syncytial Virus-Enhanced Airway Hyperresponsiveness and Inflammation by Inhibiting Th17 Memory Responses and Promoting Tissue-Resident Memory Cells in Lung ( Deng, Y; Du, X; Hai, Y; Li, H; Li, N; Li, W; Wei, L; Yin, W; Zeng, R; Zhang, L; Zhang, Z; Zheng, B, 2017)
" A dose-response relationship to vaccine dose was observed for ELISA, neutralizing and antifusion antibodies."1.29Enhanced pulmonary pathology associated with the use of formalin-inactivated respiratory syncytial virus vaccine in cotton rats is not a unique viral phenomenon. ( Ambrose, MW; Castleman, WL; Hildreth, SW; Jewell, AM; Piedra, PA; Speelman, DJ; Wyde, PR, 1993)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (20.59)18.2507
2000's14 (41.18)29.6817
2010's11 (32.35)24.3611
2020's2 (5.88)2.80

Authors

AuthorsStudies
Lin, M2
Zhang, W2
Yin, YF1
Si, JY2
Zhang, LJ2
Chen, L2
Lin, X2
Wang, YB2
Zhang, J1
Zheng, ZZ2
Xia, NS2
Chen, F1
Park, HR1
Ji, HJ1
Kwon, Y1
Kim, MK1
Song, JY1
Ahn, KB1
Seo, HS1
Yin, W2
Li, HY1
Zheng, BY1
Deng, YQ1
Li, WJ1
Liu, Y1
Zeng, RH1
Zhan, LT1
Zhao, M1
Wu, GH1
Sun, YP1
Yu, C1
Fang, MJ1
Derscheid, RJ1
Gallup, JM1
Knudson, CJ1
Varga, SM2
Grosz, DD1
van Geelen, A1
Hostetter, SJ1
Ackermann, MR1
Rey, GU1
Miao, C1
Caidi, H1
Trivedi, SU1
Harcourt, JL1
Tripp, RA2
Anderson, LJ3
Haynes, LM1
Srinivasa, BT1
Fixman, ED1
Ward, BJ1
Lee, JS2
Cho, MK1
Hwang, HS3
Ko, EJ2
Lee, YN3
Kwon, YM2
Kim, MC3
Kim, KH2
Lee, YT3
Jung, YJ2
Kang, SM3
Moore, ML1
Lee, Y1
Sawada, A1
Nakayama, T1
Muralidharan, A1
Li, C1
Wang, L1
Li, X1
Zhang, L1
Li, H1
Hai, Y1
Li, W1
Zheng, B1
Du, X1
Li, N1
Zhang, Z1
Deng, Y1
Zeng, R1
Wei, L1
De Swart, RL1
Kuiken, T1
Timmerman, HH1
van Amerongen, G1
Van Den Hoogen, BG1
Vos, HW1
Neijens, HJ1
Andeweg, AC1
Osterhaus, AD1
Johnson, TR2
Parker, RA1
Johnson, JE1
Graham, BS3
Plotnicky, H1
Siegrist, CA1
Aubry, JP1
Bonnefoy, JY1
Corvaïa, N1
Nguyen, TN1
Power, UF1
Braciale, TJ1
Delgado, MF1
Polack, FP1
Oumouna, M2
Mapletoft, JW2
Karvonen, BC1
Babiuk, LA2
van Drunen Littel-van den Hurk, S2
Kalina, WV1
Woolums, AR2
Gershwin, LJ2
Townsend, HG1
Gomis, S1
Moghaddam, A1
Olszewska, W1
Wang, B1
Tregoning, JS1
Helson, R1
Sattentau, QJ1
Openshaw, PJ1
Piedra, PA1
Wyde, PR1
Castleman, WL1
Ambrose, MW1
Jewell, AM1
Speelman, DJ1
Hildreth, SW1
Connors, M1
Giese, NA1
Kulkarni, AB1
Firestone, CY1
Morse, HC1
Murphy, BR1
Waris, ME1
Tsou, C1
Erdman, DD1
Zaki, SR1
Wright, C1
Oliver, KC1
Fenwick, FI1
Smith, NM1
Toms, GL1
West, K1
Petrie, L1
Haines, DM1
Konoby, C1
Clark, EG1
Martin, K1
Ellis, JA1
Singer, RS1
Boyle, GA1
Peebles, RS1
Sheller, JR1
Collins, RD1
Jarzecka, K1
Mitchell, DB1
Boelen, A1
Andeweg, A1
Kwakkel, J1
Lokhorst, W1
Bestebroer, T1
Dormans, J1
Kimman, T1
Prince, GA2
Denamur, F1
Deschamps, M1
Garçon, N1
Prieels, JP1
Slaoui, M1
Thiriart, C1
Porter, DD2
Ponnuraj, EM1
Hayward, AR1
Raj, A1
Wilson, H1
Simoes, EAF1
Curtis, SJ1
Yim, KC1

Reviews

2 reviews available for formaldehyde and Respiratory Syncytial Virus Infections

ArticleYear
Immunopathogenesis associated with formaldehyde-inactivated RSV vaccine in preclinical and clinical studies.
    Expert review of vaccines, 2017, Volume: 16, Issue:4

    Topics: Animals; Disease Models, Animal; Formaldehyde; Humans; Respiratory Syncytial Virus Infections; Respi

2017
Involvement of antibody, complement and cellular immunity in the pathogenesis of enhanced respiratory syncytial virus disease.
    Expert review of vaccines, 2004, Volume: 3, Issue:6

    Topics: Animals; Antibody Formation; Bronchopneumonia; Complement Activation; Disease Models, Animal; Formal

2004

Trials

1 trial available for formaldehyde and Respiratory Syncytial Virus Infections

ArticleYear
The effect of formalin-inactivated vaccine on respiratory disease associated with bovine respiratory syncytial virus infection in calves.
    Vaccine, 1999, Feb-26, Volume: 17, Issue:7-8

    Topics: Animals; Antibodies, Viral; Cattle; Cattle Diseases; Cytotoxicity, Immunologic; Female; Formaldehyde

1999

Other Studies

31 other studies available for formaldehyde and Respiratory Syncytial Virus Infections

ArticleYear
An Optimized FI-RSV Vaccine Effectively Protects Cotton Rats and BALB/c Mice without Causing Enhanced Respiratory Disease.
    Viruses, 2022, 09-20, Volume: 14, Issue:10

    Topics: Adjuvants, Immunologic; Animals; Antibodies, Neutralizing; Antibodies, Viral; Formaldehyde; Lung; Mi

2022
Gamma Irradiation-Inactivated Respiratory Syncytial Virus Vaccine Provides Protection but Exacerbates Pulmonary Inflammation by Switching from Prefusion to Postfusion F Protein.
    Microbiology spectrum, 2023, 08-17, Volume: 11, Issue:4

    Topics: Animals; Antibodies, Viral; Formaldehyde; Lung; Mice; Pneumonia; Reactive Oxygen Species; Respirator

2023
Lipopolysaccharide Inhibits FI-RSV Vaccine-enhanced Inflammation Through Regulating Th Responses.
    Current medical science, 2019, Volume: 39, Issue:3

    Topics: Adjuvants, Immunologic; Animals; Antibodies, Viral; Female; Formaldehyde; Interleukin-17; Interleuki

2019
The Optimal Concentration of Formaldehyde is Key to Stabilizing the Pre-Fusion Conformation of Respiratory Syncytial Virus Fusion Protein.
    Viruses, 2019, 07-08, Volume: 11, Issue:7

    Topics: Animals; Antibodies, Neutralizing; Antibodies, Viral; Cell Line; Disease Models, Animal; Epitopes; F

2019
Effects of formalin-inactivated respiratory syncytial virus (FI-RSV) in the perinatal lamb model of RSV.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Animals; Animals, Newborn; Antigens, Viral; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Fo

2013
Decrease in formalin-inactivated respiratory syncytial virus (FI-RSV) enhanced disease with RSV G glycoprotein peptide immunization in BALB/c mice.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Amino Acid Sequence; Animals; Antibodies, Viral; Formaldehyde; Immunization; Lung; Mice; Mice, Inbre

2013
Inhibition of STAT6 during vaccination with formalin-inactivated RSV prevents induction of Th2-cell-biased airway disease.
    European journal of immunology, 2014, Volume: 44, Issue:8

    Topics: Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Line; Cytokines; Eosinophils;

2014
Ginseng diminishes lung disease in mice immunized with formalin-inactivated respiratory syncytial virus after challenge by modulating host immune responses.
    Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 2014, Volume: 34, Issue:11

    Topics: Animals; Female; Formaldehyde; Hep G2 Cells; Humans; Immunization; Immunoglobulin G; Immunomodulatio

2014
Recombinant influenza virus expressing a fusion protein neutralizing epitope of respiratory syncytial virus (RSV) confers protection without vaccine-enhanced RSV disease.
    Antiviral research, 2015, Volume: 115

    Topics: Administration, Intranasal; Animals; Antibodies, Neutralizing; Antibodies, Viral; Epitopes; Formalde

2015
Innate and adaptive cellular phenotypes contributing to pulmonary disease in mice after respiratory syncytial virus immunization and infection.
    Virology, 2015, Volume: 485

    Topics: Adaptive Immunity; Animals; CD4-Positive T-Lymphocytes; Clodronic Acid; Dendritic Cells; Eosinophils

2015
Experimental animal model for analyzing immunobiological responses following vaccination with formalin-inactivated respiratory syncytial virus.
    Microbiology and immunology, 2016, Volume: 60, Issue:4

    Topics: Animals; Antibodies, Viral; Cytokines; Formaldehyde; Lung; Measles virus; Models, Animal; Palivizuma

2016
CpG in Combination with an Inhibitor of Notch Signaling Suppresses Formalin-Inactivated Respiratory Syncytial Virus-Enhanced Airway Hyperresponsiveness and Inflammation by Inhibiting Th17 Memory Responses and Promoting Tissue-Resident Memory Cells in Lung
    Journal of virology, 2017, 05-15, Volume: 91, Issue:10

    Topics: Adjuvants, Immunologic; Animals; Bronchial Hyperreactivity; Carbamates; CD8-Positive T-Lymphocytes;

2017
Immunization of macaques with formalin-inactivated respiratory syncytial virus (RSV) induces interleukin-13-associated hypersensitivity to subsequent RSV infection.
    Journal of virology, 2002, Volume: 76, Issue:22

    Topics: Animals; Animals, Newborn; Asthma; Bronchial Hyperreactivity; Formaldehyde; Humans; Immunization; In

2002
IL-13 is sufficient for respiratory syncytial virus G glycoprotein-induced eosinophilia after respiratory syncytial virus challenge.
    Journal of immunology (Baltimore, Md. : 1950), 2003, Feb-15, Volume: 170, Issue:4

    Topics: Animals; Antibodies, Viral; Antibody Specificity; Cell Line; Cytokines; Formaldehyde; HN Protein; Hu

2003
Enhanced pulmonary immunopathology following neonatal priming with formalin-inactivated respiratory syncytial virus but not with the BBG2NA vaccine candidate.
    Vaccine, 2003, Jun-02, Volume: 21, Issue:19-20

    Topics: Animals; Animals, Newborn; Antibodies, Viral; CD4-Positive T-Lymphocytes; Enzyme-Linked Immunosorben

2003
Vbeta14(+) T cells mediate the vaccine-enhanced disease induced by immunization with respiratory syncytial virus (RSV) G glycoprotein but not with formalin-inactivated RSV.
    Journal of virology, 2004, Volume: 78, Issue:16

    Topics: Animals; Formaldehyde; Immunization; Mice; Mice, Inbred BALB C; Pulmonary Eosinophilia; Receptors, A

2004
Formulation with CpG oligodeoxynucleotides prevents induction of pulmonary immunopathology following priming with formalin-inactivated or commercial killed bovine respiratory syncytial virus vaccine.
    Journal of virology, 2005, Volume: 79, Issue:4

    Topics: Adjuvants, Immunologic; Animals; Cell Line; Chemistry, Pharmaceutical; Formaldehyde; Immunization; I

2005
Formalin-inactivated bovine RSV vaccine influences antibody levels in bronchoalveolar lavage fluid and disease outcome in experimentally infected calves.
    Vaccine, 2005, Aug-31, Volume: 23, Issue:37

    Topics: Animals; Antibodies, Viral; Antibody Formation; Bronchoalveolar Lavage; Cattle; Cattle Diseases; For

2005
Formulation with CpG oligodeoxynucleotides increases cellular immunity and protection induced by vaccination of calves with formalin-inactivated bovine respiratory syncytial virus.
    Virology, 2006, Sep-30, Volume: 353, Issue:2

    Topics: Adjuvants, Immunologic; Animals; Animals, Suckling; Antibodies, Viral; Cattle; Chemistry, Pharmaceut

2006
A potential molecular mechanism for hypersensitivity caused by formalin-inactivated vaccines.
    Nature medicine, 2006, Volume: 12, Issue:8

    Topics: Animals; Antigens, Viral; Bronchoalveolar Lavage Fluid; Eosinophilia; Formaldehyde; Immunization; In

2006
Enhanced pulmonary pathology associated with the use of formalin-inactivated respiratory syncytial virus vaccine in cotton rats is not a unique viral phenomenon.
    Vaccine, 1993, Volume: 11, Issue:14

    Topics: Animals; Antibodies, Viral; Antibody Formation; Antigens, Viral; Chlorocebus aethiops; Epitopes; For

1993
Enhanced pulmonary histopathology induced by respiratory syncytial virus (RSV) challenge of formalin-inactivated RSV-immunized BALB/c mice is abrogated by depletion of interleukin-4 (IL-4) and IL-10.
    Journal of virology, 1994, Volume: 68, Issue:8

    Topics: Animals; Formaldehyde; Immunization; Interferon-gamma; Interleukin-10; Interleukin-2; Interleukin-4;

1994
Respiratory synctial virus infection in BALB/c mice previously immunized with formalin-inactivated virus induces enhanced pulmonary inflammatory response with a predominant Th2-like cytokine pattern.
    Journal of virology, 1996, Volume: 70, Issue:5

    Topics: Animals; Base Sequence; Bronchoalveolar Lavage Fluid; CD4 Lymphocyte Count; Cytokines; DNA Primers;

1996
A monoclonal antibody pool for routine immunohistochemical detection of human respiratory syncytial virus antigens in formalin-fixed, paraffin-embedded tissue.
    The Journal of pathology, 1997, Volume: 182, Issue:2

    Topics: Antibodies, Monoclonal; Antigens, Viral; Ascitic Fluid; Bronchiolitis, Viral; Formaldehyde; Humans;

1997
Cytotoxic T-lymphocyte precursor frequencies in BALB/c mice after acute respiratory syncytial virus (RSV) infection or immunization with a formalin-inactivated RSV vaccine.
    Journal of virology, 1998, Volume: 72, Issue:11

    Topics: Animals; Bronchoalveolar Lavage Fluid; Female; Formaldehyde; Histocompatibility Antigens Class I; Hi

1998
Interferon gamma production during bovine respiratory syncytial virus (BRSV) infection is diminished in calves vaccinated with formalin-inactivated BRSV.
    Vaccine, 1999, Mar-17, Volume: 17, Issue:11-12

    Topics: Animals; Cattle; Cattle Diseases; Enzyme-Linked Immunosorbent Assay; Formaldehyde; Interferon-gamma;

1999
Respiratory syncytial virus (RSV)-induced airway hyperresponsiveness in allergically sensitized mice is inhibited by live RSV and exacerbated by formalin-inactivated RSV.
    The Journal of infectious diseases, 2000, Volume: 182, Issue:3

    Topics: Administration, Intranasal; Animals; Disease Models, Animal; Female; Formaldehyde; Methacholine Chlo

2000
Both immunisation with a formalin-inactivated respiratory syncytial virus (RSV) vaccine and a mock antigen vaccine induce severe lung pathology and a Th2 cytokine profile in RSV-challenged mice.
    Vaccine, 2000, Nov-22, Volume: 19, Issue:7-8

    Topics: Animals; Antibodies, Viral; Child, Preschool; Cytokines; Female; Formaldehyde; Humans; Immunization;

2000
Monophosphoryl lipid A adjuvant reverses a principal histologic parameter of formalin-inactivated respiratory syncytial virus vaccine-induced disease.
    Vaccine, 2001, Feb-28, Volume: 19, Issue:15-16

    Topics: Adjuvants, Immunologic; Animals; Child; Female; Formaldehyde; Humans; Lipid A; Male; Pulmonary Alveo

2001
Increased replication of respiratory syncytial virus (RSV) in pulmonary infiltrates is associated with enhanced histopathological disease in bonnet monkeys (Macaca radiata) pre-immunized with a formalin-inactivated RSV vaccine.
    The Journal of general virology, 2001, Volume: 82, Issue:Pt 11

    Topics: Animals; Disease Models, Animal; Formaldehyde; Humans; Inflammation; Lung; Macaca radiata; Respirato

2001
Vaccine-enhanced respiratory syncytial virus disease in cotton rats following immunization with Lot 100 or a newly prepared reference vaccine.
    The Journal of general virology, 2001, Volume: 82, Issue:Pt 12

    Topics: Animals; Autopsy; Bronchiolitis; Disease Models, Animal; Female; Formaldehyde; Humans; Lung; Male; P

2001