formaldehyde has been researched along with Parkinson Disease in 13 studies
paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We show that fixed tissue from Parkinson's disease (PD) and incidental Lewy body disease (ILBD) seeds the aggregation of monomeric αSyn into fibrillar assemblies." | 1.62 | Seeding Propensity and Characteristics of Pathogenic αSyn Assemblies in Formalin-Fixed Human Tissue from the Enteric Nervous System, Olfactory Bulb, and Brainstem in Cases Staged for Parkinson's Disease. ( Bousset, L; Braak, H; Del Tredici, K; Duyckaerts, C; Fenyi, A; Melki, R, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 3 (23.08) | 2.80 |
| Authors | Studies |
|---|---|
| Shin, C | 1 |
| Han, JY | 1 |
| Kim, SI | 1 |
| Park, SH | 1 |
| Yang, HK | 1 |
| Lee, HJ | 1 |
| Kong, SH | 1 |
| Suh, YS | 1 |
| Kim, HJ | 1 |
| Choi, YP | 1 |
| Jeon, B | 1 |
| Quan, W | 1 |
| Zhang, G | 1 |
| Li, Y | 1 |
| Song, W | 1 |
| Zhan, J | 1 |
| Lin, W | 1 |
| Ruesink, H | 1 |
| Reimer, L | 1 |
| Gregersen, E | 1 |
| Moeller, A | 1 |
| Betzer, C | 1 |
| Jensen, PH | 1 |
| Maegawa, H | 2 |
| Adachi, N | 1 |
| Hanamoto, H | 2 |
| Kudo, C | 2 |
| Niwa, H | 2 |
| Fenyi, A | 1 |
| Duyckaerts, C | 1 |
| Bousset, L | 1 |
| Braak, H | 1 |
| Del Tredici, K | 1 |
| Melki, R | 1 |
| Morimoto, Y | 1 |
| Boku, A | 1 |
| Sugimura, M | 1 |
| Kato, T | 1 |
| Yoshida, A | 1 |
| Hopp, K | 1 |
| Popescu, BF | 1 |
| McCrea, RP | 1 |
| Harder, SL | 1 |
| Robinson, CA | 1 |
| Haacke, ME | 1 |
| Rajput, AH | 1 |
| Rajput, A | 1 |
| Nichol, H | 1 |
| Liu, CQ | 1 |
| Shan, L | 1 |
| Balesar, R | 1 |
| Luchetti, S | 1 |
| Van Heerikhuize, JJ | 1 |
| Luo, JH | 1 |
| Swaab, DF | 1 |
| Bao, AM | 1 |
| Gellein, K | 1 |
| Garruto, RM | 1 |
| Syversen, T | 1 |
| Sjøbakk, TE | 1 |
| Flaten, TP | 1 |
| Stauber, J | 1 |
| Lemaire, R | 1 |
| Franck, J | 1 |
| Bonnel, D | 1 |
| Croix, D | 1 |
| Day, R | 1 |
| Wisztorski, M | 1 |
| Fournier, I | 1 |
| Salzet, M | 1 |
| Bellows, JG | 1 |
| Rahamim, E | 1 |
| Kahane, A | 1 |
| Sharon, R | 1 |
| Roy, S | 1 |
| Wolman, L | 1 |
13 other studies available for formaldehyde and Parkinson Disease
| Article | Year |
|---|---|
In vivo and autopsy validation of alpha-synuclein seeding activity using RT-QuIC assay in the gastrointestinal tract of patients with Parkinson's disease.
Topics: alpha-Synuclein; Autopsy; Biomarkers; Case-Control Studies; Formaldehyde; Gastrointestinal Tract; Hu | 2022 |
Upregulation of Formaldehyde in Parkinson's Disease Found by a Near-Infrared Lysosome-Targeted Fluorescent Probe.
Topics: Animals; Fluorescent Dyes; Formaldehyde; HeLa Cells; Humans; Lysosomes; Mice; Parkinson Disease; Up- | 2023 |
Stabilization of α-synuclein oligomers using formaldehyde.
Topics: alpha-Synuclein; Amyloid; Formaldehyde; Humans; Lewy Body Disease; Multiple System Atrophy; Parkinso | 2019 |
Bilateral Parkinson's disease model rats exhibit hyperalgesia to subcutaneous formalin administration into the vibrissa pad.
Topics: Animals; Corpus Striatum; Disease Models, Animal; Formaldehyde; Hyperalgesia; Immunohistochemistry; | 2019 |
Seeding Propensity and Characteristics of Pathogenic αSyn Assemblies in Formalin-Fixed Human Tissue from the Enteric Nervous System, Olfactory Bulb, and Brainstem in Cases Staged for Parkinson's Disease.
Topics: Adult; Aged; Aged, 80 and over; alpha-Synuclein; Brain Stem; Enteric Nervous System; Female; Formald | 2021 |
Neural mechanism underlying hyperalgesic response to orofacial pain in Parkinson's disease model rats.
Topics: Animals; Corpus Striatum; Disease Models, Animal; Facial Pain; Formaldehyde; Hyperalgesia; Male; Oxi | 2015 |
Brain iron detected by SWI high pass filtered phase calibrated with synchrotron X-ray fluorescence.
Topics: Alzheimer Disease; Brain; Brain Injuries; Brain Mapping; Cadaver; Calibration; Formaldehyde; Humans; | 2010 |
A quantitative in situ hybridization protocol for formalin-fixed paraffin-embedded archival post-mortem human brain tissue.
Topics: Aged; Aged, 80 and over; Autopsy; Autoradiography; Brain Chemistry; Corticotropin-Releasing Hormone; | 2010 |
Concentrations of Cd, Co, Cu, Fe, Mn, Rb, V, and Zn in formalin-fixed brain tissue in amyotrophic lateral sclerosis and Parkinsonism-dementia complex of Guam determined by High-resolution ICP-MS.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Animals; Brain Chemistry; Cattle; Dementia; Female; Form | 2003 |
MALDI imaging of formalin-fixed paraffin-embedded tissues: application to model animals of Parkinson disease for biomarker hunting.
Topics: Animals; Biomarkers; Chromatography, Liquid; Disease Models, Animal; Formaldehyde; Male; Paraffin Em | 2008 |
Introduction to cryosurgery.
Topics: Carbon Dioxide; Cataract Extraction; Cryosurgery; Epistaxis; Female; Formaldehyde; Humans; Hydrocarb | 1967 |
Electron microscopy of red blood cells altered by auto-immunity-inducing drugs.
Topics: Anemia, Hemolytic, Autoimmune; Autoimmunity; Enzyme-Linked Immunosorbent Assay; Erythrocytes; Formal | 1990 |
Ultrastructure and significance of microorganisms found in the formalin-fixed brain from a case of Parkinsonism.
Topics: Aged; Autopsy; Cell Wall; Cerebral Hemorrhage; Clostridium; Cytoplasmic Granules; Formaldehyde; Hist | 1970 |