Page last updated: 2024-10-18

formaldehyde and Pain, Chronic

formaldehyde has been researched along with Pain, Chronic in 26 studies

paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy

Research Excerpts

ExcerptRelevanceReference
"Luteolin is a naturally occurring flavonoid with diverse pharmacological properties such as anti-inflammatory, antioxidant and anticancer."5.46Effects of luteolin and luteolin-morphine co-administration on acute and chronic pain and sciatic nerve ligated-induced neuropathy in mice. ( Abdollahzadeh, M; Golmakani, E; Hashemzaei, M; Iranshahi, M; Rezaee, R; Tabrizian, K, 2017)
"Acute pain was determined using the hot plate test (thermal nociception) and the formalin test (inflammatory pain)."5.40The oral administration of trans-caryophyllene attenuates acute and chronic pain in mice. ( Andersen, ML; Carlini, EL; Gama, VS; Molska, GR; Paula-Freire, LI, 2014)
"Ipsilateral, but not contralateral, pre-treatment (in μg/paw) with sumatriptan (10-300), methysergide (1-30) or dihydroergotamine (1-30) significantly prevented flinching behavior (at 1h) as well as secondary allodynia and hyperalgesia (at day 6) induced by formalin."3.79Role of 5-HT₁B/₁D receptors in the reduction of formalin-induced nociception and secondary allodynia/hyperalgesia produced by antimigraine drugs in rats. ( Argüelles, CF; Godínez-Chaparro, B; Granados-Soto, V; López-Santillán, FJ; Villalón, CM, 2013)
"Chronic pain is a common disease that severely disrupts the quality of life."1.91Caspase-11 contributes to pain hypersensitivity in the later phase of CFA-induced pain of mice. ( Cao, W; Cheng, Y; Liu, M; Qin, X; Tong, J; Wu, X, 2023)
"Heat and mechanical hyperalgesia were evaluated by radiant heat and von Frey filament tests, respectively."1.91Mechanisms involved in the antinociceptive and anti-inflammatory effects of xanthotoxin. ( Guo, J; Song, Y; Tang, J; Tang, Z; Yang, Y; Yu, G; Zhu, C, 2023)
"Chronic pain is recognized as an important problem in communities."1.62Formalin-induced inflammatory pain increases excitability in locus coeruleus neurons. ( Azizi, H; Farahani, F; Janahmadi, M; Semnanian, S; Seutin, V, 2021)
"The poncirin (30 mg/kg) treatment considerably inhibited the mechanical hyperalgesia and allodynia as well as thermal hyperalgesia and cold allodynia."1.51Anti-hyperalgesic properties of a flavanone derivative Poncirin in acute and chronic inflammatory pain models in mice. ( Afridi, R; Khalid, S; Khan, AU; Khan, S; Kim, YS; Rasheed, H; Shal, B; Shehzad, O; Ullah, MZ, 2019)
"Furthermore, long-lasting bilateral hyperalgesia could be reversed by pharmacological inhibition of over-expressed spinal PKCγ; however, pretreating with intrathecal KIG31-1 showed no antinociceptive effects on short-term spontaneous pain behaviors."1.48Contribution of Spinal PKCγ Expression to Short- and Long-lasting Pain Behaviors in Formalin-induced Inflamed Mice. ( Chen, DS; Chen, GZ; Ding, T; Guo, XJ; Liang, JC; Tang, K; Wang, Y; Wu, HH; Yin, JB; Zhao, YQ, 2018)
"Luteolin is a naturally occurring flavonoid with diverse pharmacological properties such as anti-inflammatory, antioxidant and anticancer."1.46Effects of luteolin and luteolin-morphine co-administration on acute and chronic pain and sciatic nerve ligated-induced neuropathy in mice. ( Abdollahzadeh, M; Golmakani, E; Hashemzaei, M; Iranshahi, M; Rezaee, R; Tabrizian, K, 2017)
"Insufficient sleep and chronic pain are public health epidemics."1.43Sleep Deprivation and Recovery Sleep Prior to a Noxious Inflammatory Insult Influence Characteristics and Duration of Pain. ( Vanini, G, 2016)
"In vivo, IT LPS evoked tactile allodynia to a greater degree in male than female mice."1.43Systemic TAK-242 prevents intrathecal LPS evoked hyperalgesia in male, but not female mice and prevents delayed allodynia following intraplantar formalin in both male and female mice: The role of TLR4 in the evolution of a persistent pain state. ( Beaton, G; Chigbrow, M; Corr, M; Eddinger, KA; Isseroff, RR; Ravula, SB; Soulika, AM; Tucci, FC; Woller, SA; Yaksh, TL, 2016)
"Acute pain was determined using the hot plate test (thermal nociception) and the formalin test (inflammatory pain)."1.40The oral administration of trans-caryophyllene attenuates acute and chronic pain in mice. ( Andersen, ML; Carlini, EL; Gama, VS; Molska, GR; Paula-Freire, LI, 2014)
"Finally, despite chronic pain perception in control and unstable male subjects was larger than females; the decrease of chronic pain perception in male stressed animals (poverty and inequality experienced subjects) was much more than stressed females."1.38The effect of social stress on chronic pain perception in female and male mice. ( Aghajani, M; Ghazanfari, T; Khalili Najafabadi, M; Vaez Mahdavi, MR, 2012)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's19 (73.08)24.3611
2020's7 (26.92)2.80

Authors

AuthorsStudies
Liu, M3
Cao, W3
Qin, X3
Tong, J3
Wu, X3
Cheng, Y3
Pepino, L1
Malapert, P1
Saurin, AJ1
Moqrich, A1
Reynders, A1
Zhu, C1
Yang, Y1
Song, Y1
Guo, J1
Yu, G1
Tang, J1
Tang, Z1
Afridi, R1
Khan, AU1
Khalid, S1
Shal, B1
Rasheed, H1
Ullah, MZ1
Shehzad, O1
Kim, YS1
Khan, S1
Lee, JY1
Lee, GJ1
Lee, PR1
Won, CH1
Kim, D1
Kang, Y1
Oh, SB1
Jiang, ZJ1
Li, QY1
Zhang, YY1
Zeng, MX1
Hu, H1
Zhang, FM1
Bi, LB1
Gu, JH1
Liu, XJ1
Nakamura, Y1
Okano, Y1
Sato, M1
Kobayashi, M1
Yamaguchi, T1
Sumi, T1
Koyama, Y1
Kondo, M1
Usui, N1
Shimada, S1
Farahani, F1
Azizi, H1
Janahmadi, M1
Seutin, V1
Semnanian, S1
Takahara-Yamauchi, R1
Ikemoto, H1
Okumo, T1
Sakhri, FZ1
Horikawa, H1
Nakamura, A1
Sakaue, S1
Kato, M1
Adachi, N1
Sunagawa, M1
Sikandar, S1
Minett, MS1
Millet, Q1
Santana-Varela, S1
Lau, J1
Wood, JN1
Zhao, J1
Zhao, YQ1
Yin, JB1
Wu, HH1
Ding, T1
Wang, Y1
Liang, JC1
Guo, XJ1
Tang, K1
Chen, DS1
Chen, GZ1
Kataoka, K1
Hara, K1
Haranishi, Y1
Terada, T1
Sata, T1
Godínez-Chaparro, B1
López-Santillán, FJ1
Argüelles, CF1
Villalón, CM1
Granados-Soto, V1
Paula-Freire, LI1
Andersen, ML1
Gama, VS1
Molska, GR1
Carlini, EL1
Demeule, M1
Beaudet, N2
Régina, A1
Besserer-Offroy, É1
Murza, A1
Tétreault, P2
Belleville, K2
Ché, C1
Larocque, A1
Thiot, C1
Béliveau, R1
Longpré, JM2
Marsault, É1
Leduc, R1
Lachowicz, JE1
Gonias, SL1
Castaigne, JP1
Sarret, P2
Nishijima, CM1
Ganev, EG1
Mazzardo-Martins, L2
Martins, DF2
Rocha, LR1
Santos, AR2
Hiruma-Lima, CA1
Obniska, J1
Sałat, K1
Librowski, T1
Kamiński, K1
Lipkowska, A1
Wiklik, B1
Rybka, S1
Rapacz, A1
Vanini, G1
Parent, AJ1
Roux, M1
Goffaux, P1
Silva, M1
Martins, D1
Charrua, A1
Piscitelli, F1
Tavares, I1
Morgado, C1
Di Marzo, V1
Woller, SA1
Ravula, SB1
Tucci, FC1
Beaton, G1
Corr, M1
Isseroff, RR1
Soulika, AM1
Chigbrow, M1
Eddinger, KA1
Yaksh, TL1
Kang, DW1
Moon, JY1
Choi, JG1
Kang, SY1
Ryu, Y1
Park, JB1
Lee, JH1
Kim, HW1
Hashemzaei, M1
Abdollahzadeh, M1
Iranshahi, M1
Golmakani, E1
Rezaee, R1
Tabrizian, K1
Huh, Y1
Bhatt, R1
Jung, D1
Shin, HS1
Cho, J1
Nucci, C1
Stramosk, J1
Brethanha, LC1
Pizzolatti, MG1
Aghajani, M1
Vaez Mahdavi, MR1
Khalili Najafabadi, M1
Ghazanfari, T1

Other Studies

26 other studies available for formaldehyde and Pain, Chronic

ArticleYear
Caspase-11 contributes to pain hypersensitivity in the later phase of CFA-induced pain of mice.
    Brain research, 2023, 02-15, Volume: 1801

    Topics: Animals; Chronic Pain; Formaldehyde; Freund's Adjuvant; Hyperalgesia; Hypersensitivity; Inflammation

2023
Caspase-11 contributes to pain hypersensitivity in the later phase of CFA-induced pain of mice.
    Brain research, 2023, 02-15, Volume: 1801

    Topics: Animals; Chronic Pain; Formaldehyde; Freund's Adjuvant; Hyperalgesia; Hypersensitivity; Inflammation

2023
Caspase-11 contributes to pain hypersensitivity in the later phase of CFA-induced pain of mice.
    Brain research, 2023, 02-15, Volume: 1801

    Topics: Animals; Chronic Pain; Formaldehyde; Freund's Adjuvant; Hyperalgesia; Hypersensitivity; Inflammation

2023
Caspase-11 contributes to pain hypersensitivity in the later phase of CFA-induced pain of mice.
    Brain research, 2023, 02-15, Volume: 1801

    Topics: Animals; Chronic Pain; Formaldehyde; Freund's Adjuvant; Hyperalgesia; Hypersensitivity; Inflammation

2023
Caspase-11 contributes to pain hypersensitivity in the later phase of CFA-induced pain of mice.
    Brain research, 2023, 02-15, Volume: 1801

    Topics: Animals; Chronic Pain; Formaldehyde; Freund's Adjuvant; Hyperalgesia; Hypersensitivity; Inflammation

2023
Caspase-11 contributes to pain hypersensitivity in the later phase of CFA-induced pain of mice.
    Brain research, 2023, 02-15, Volume: 1801

    Topics: Animals; Chronic Pain; Formaldehyde; Freund's Adjuvant; Hyperalgesia; Hypersensitivity; Inflammation

2023
Caspase-11 contributes to pain hypersensitivity in the later phase of CFA-induced pain of mice.
    Brain research, 2023, 02-15, Volume: 1801

    Topics: Animals; Chronic Pain; Formaldehyde; Freund's Adjuvant; Hyperalgesia; Hypersensitivity; Inflammation

2023
Caspase-11 contributes to pain hypersensitivity in the later phase of CFA-induced pain of mice.
    Brain research, 2023, 02-15, Volume: 1801

    Topics: Animals; Chronic Pain; Formaldehyde; Freund's Adjuvant; Hyperalgesia; Hypersensitivity; Inflammation

2023
Caspase-11 contributes to pain hypersensitivity in the later phase of CFA-induced pain of mice.
    Brain research, 2023, 02-15, Volume: 1801

    Topics: Animals; Chronic Pain; Formaldehyde; Freund's Adjuvant; Hyperalgesia; Hypersensitivity; Inflammation

2023
Formalin-evoked pain triggers sex-specific behavior and spinal immune response.
    Scientific reports, 2023, 06-12, Volume: 13, Issue:1

    Topics: Animals; Chronic Pain; Female; Formaldehyde; Humans; Male; Mice; Oncogenes; Pain Perception; Spinal

2023
Mechanisms involved in the antinociceptive and anti-inflammatory effects of xanthotoxin.
    The European journal of neuroscience, 2023, Volume: 58, Issue:7

    Topics: Acute Pain; Analgesics; Animals; Anti-Inflammatory Agents; Capsaicin; Chronic Pain; Formaldehyde; Ga

2023
Anti-hyperalgesic properties of a flavanone derivative Poncirin in acute and chronic inflammatory pain models in mice.
    BMC pharmacology & toxicology, 2019, 09-11, Volume: 20, Issue:1

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Chronic Pain; Disease Mo

2019
The analgesic effect of refeeding on acute and chronic inflammatory pain.
    Scientific reports, 2019, 11-14, Volume: 9, Issue:1

    Topics: Acute Pain; Analgesics, Opioid; Animals; Chronic Pain; Disease Models, Animal; Eating; Food Deprivat

2019
Deletion of MyD88 adaptor in nociceptor alleviates low-dose formalin-induced acute pain and persistent pain in mice.
    Neuroreport, 2021, 03-24, Volume: 32, Issue:5

    Topics: Acute Pain; Animals; Chronic Pain; Formaldehyde; Mice; Mice, Knockout; Myeloid Differentiation Facto

2021
Pain-like behavior in mice can be induced by the environmental context in which the pain stimulus was previously given.
    Neuroreport, 2021, 03-24, Volume: 32, Issue:5

    Topics: Animals; Association Learning; Behavior, Animal; Chronic Pain; Conditioning, Classical; Disease Mode

2021
Formalin-induced inflammatory pain increases excitability in locus coeruleus neurons.
    Brain research bulletin, 2021, Volume: 172

    Topics: Action Potentials; Animals; Chronic Pain; Formaldehyde; Inflammation; Locus Coeruleus; Male; Neurons

2021
Analgesic effect of voluntary exercise in a rat model of persistent pain via suppression of microglial activation in the spinal cord.
    Biomedical research (Tokyo, Japan), 2021, Volume: 42, Issue:2

    Topics: Analgesics; Animals; Brain-Derived Neurotrophic Factor; Cell Proliferation; Chronic Pain; Disease Mo

2021
Brain-derived neurotrophic factor derived from sensory neurons plays a critical role in chronic pain.
    Brain : a journal of neurology, 2018, 04-01, Volume: 141, Issue:4

    Topics: Animals; Brain-Derived Neurotrophic Factor; Carrageenan; Chronic Pain; Disease Models, Animal; Femal

2018
Contribution of Spinal PKCγ Expression to Short- and Long-lasting Pain Behaviors in Formalin-induced Inflamed Mice.
    Pain physician, 2018, Volume: 21, Issue:5

    Topics: Animals; Behavior, Animal; China; Chronic Pain; Formaldehyde; Hyperalgesia; Male; Mice; Pain Measure

2018
The antinociceptive effect of SNAP5114, a gamma-aminobutyric acid transporter-3 inhibitor, in rat experimental pain models.
    Anesthesia and analgesia, 2013, Volume: 116, Issue:5

    Topics: Acute Pain; Analgesics; Animals; Anisoles; Behavior, Animal; Chronic Pain; Constriction, Pathologic;

2013
Role of 5-HT₁B/₁D receptors in the reduction of formalin-induced nociception and secondary allodynia/hyperalgesia produced by antimigraine drugs in rats.
    Life sciences, 2013, Jun-13, Volume: 92, Issue:22

    Topics: Acute Pain; Animals; Biphenyl Compounds; Chronic Pain; Dihydroergotamine; Disease Models, Animal; Dr

2013
The oral administration of trans-caryophyllene attenuates acute and chronic pain in mice.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2014, Feb-15, Volume: 21, Issue:3

    Topics: Acute Pain; Administration, Oral; Analgesics; Animals; Cannabis; Chronic Pain; Formaldehyde; Hot Tem

2014
Conjugation of a brain-penetrant peptide with neurotensin provides antinociceptive properties.
    The Journal of clinical investigation, 2014, Volume: 124, Issue:3

    Topics: Analgesics; Animals; Blood-Brain Barrier; Bone Neoplasms; Capillary Permeability; Cell Line; Cell Li

2014
Citral: a monoterpene with prophylactic and therapeutic anti-nociceptive effects in experimental models of acute and chronic pain.
    European journal of pharmacology, 2014, Aug-05, Volume: 736

    Topics: Acute Pain; Acyclic Monoterpenes; Analgesics; Animals; Capsaicin; Chronic Pain; Excitatory Amino Aci

2014
Antinociceptive properties of N-Mannich bases derived from 3-substituted pyrrolidine-2,5-dione in the formalin model of persistent pain in mice.
    Pharmacological reports : PR, 2015, Volume: 67, Issue:1

    Topics: Analgesics; Animals; Behavior, Animal; Chronic Pain; Foot; Formaldehyde; Injections; Male; Mannich B

2015
Sleep Deprivation and Recovery Sleep Prior to a Noxious Inflammatory Insult Influence Characteristics and Duration of Pain.
    Sleep, 2016, Jan-01, Volume: 39, Issue:1

    Topics: Animals; Chronic Pain; Formaldehyde; Hyperalgesia; Inflammation; Male; Pain Measurement; Rats; Rats,

2016
Descending nociceptive inhibition is modulated in a time-dependent manner in a double-hit model of chronic/tonic pain.
    Neuroscience, 2016, Feb-19, Volume: 315

    Topics: Animals; Chromatography, Liquid; Chronic Pain; Disease Models, Animal; Formaldehyde; Hyperalgesia; M

2016
Endovanilloid control of pain modulation by the rostroventromedial medulla in an animal model of diabetic neuropathy.
    Neuropharmacology, 2016, Volume: 107

    Topics: Amides; Amidohydrolases; Analgesics, Non-Narcotic; Animals; Arachidonic Acids; Capsaicin; Chronic Pa

2016
Systemic TAK-242 prevents intrathecal LPS evoked hyperalgesia in male, but not female mice and prevents delayed allodynia following intraplantar formalin in both male and female mice: The role of TLR4 in the evolution of a persistent pain state.
    Brain, behavior, and immunity, 2016, Volume: 56

    Topics: Animals; Behavior, Animal; Chronic Pain; Disease Models, Animal; Disinfectants; Female; Formaldehyde

2016
Antinociceptive Profile of Levo-tetrahydropalmatine in Acute and Chronic Pain Mice Models: Role of spinal sigma-1 receptor.
    Scientific reports, 2016, 12-02, Volume: 6

    Topics: Analgesics; Animals; Berberine Alkaloids; Chronic Pain; Ethylenediamines; Formaldehyde; Gene Express

2016
Effects of luteolin and luteolin-morphine co-administration on acute and chronic pain and sciatic nerve ligated-induced neuropathy in mice.
    Journal of complementary & integrative medicine, 2017, Mar-01, Volume: 14, Issue:1

    Topics: Acute Disease; Analgesics; Animals; Chronic Pain; Disease Models, Animal; Drug Therapy, Combination;

2017
Interactive responses of a thalamic neuron to formalin induced lasting pain in behaving mice.
    PloS one, 2012, Volume: 7, Issue:1

    Topics: Animals; Behavior, Animal; Cell Communication; Chronic Pain; Electrophysiological Phenomena; Formald

2012
Oleaginous extract from the fruits Pterodon pubescens Benth induces antinociception in animal models of acute and chronic pain.
    Journal of ethnopharmacology, 2012, Aug-30, Volume: 143, Issue:1

    Topics: Acute Pain; Analgesics; Animals; Anti-Inflammatory Agents; Chronic Pain; Cold Temperature; Complex R

2012
The effect of social stress on chronic pain perception in female and male mice.
    PloS one, 2012, Volume: 7, Issue:10

    Topics: Animals; Body Weight; Chronic Pain; Cytokines; Female; Food Deprivation; Formaldehyde; Inflammation

2012