formaldehyde has been researched along with Nociceptive Pain in 59 studies
paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy
Nociceptive Pain: Dull or sharp aching pain caused by stimulated NOCICEPTORS due to tissue injury, inflammation or diseases. It can be divided into somatic or tissue pain and VISCERAL PAIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Luteolin is a naturally occurring flavonoid with diverse pharmacological properties such as anti-inflammatory, antioxidant and anticancer." | 5.46 | Effects of luteolin and luteolin-morphine co-administration on acute and chronic pain and sciatic nerve ligated-induced neuropathy in mice. ( Abdollahzadeh, M; Golmakani, E; Hashemzaei, M; Iranshahi, M; Rezaee, R; Tabrizian, K, 2017) |
| "The purposes of this study were to evaluate the anti-nociceptive effect of oral and topical administration of (-)-α-bisabolol (BISA) in rodent models of formalin- or cinnamaldehyde-induced orofacial pain and to explore the inhibitory mechanisms involved." | 3.85 | (-)-α-Bisabolol reduces orofacial nociceptive behavior in rodents. ( Campos, AR; da Costa, FN; de Vasconcellos Abdon, AP; Duailibe, MA; Melo, LT; Pessoa, LM; Vieira-Neto, AE, 2017) |
| " Xylene-induced ear edema, carrageenan-induced paw edema and acetic acid-induced vascular permeability test were used to investigate the anti-inflammatory activities of GL in mice." | 3.81 | Observing Anti-inflammatory and Anti-nociceptive Activities of Glycyrrhizin Through Regulating COX-2 and Pro-inflammatory Cytokines Expressions in Mice. ( Li, YX; Ma, L; Niu, Y; Niu, YT; Shi, GJ; Sun, T; Wang, HL; Wu, J; Yu, JQ; Zheng, J, 2015) |
| "Ipsilateral, but not contralateral, pre-treatment (in μg/paw) with sumatriptan (10-300), methysergide (1-30) or dihydroergotamine (1-30) significantly prevented flinching behavior (at 1h) as well as secondary allodynia and hyperalgesia (at day 6) induced by formalin." | 3.79 | Role of 5-HT₁B/₁D receptors in the reduction of formalin-induced nociception and secondary allodynia/hyperalgesia produced by antimigraine drugs in rats. ( Argüelles, CF; Godínez-Chaparro, B; Granados-Soto, V; López-Santillán, FJ; Villalón, CM, 2013) |
| "Betaine, is a methyl glycine derivative and a commonly used nutrient supplement." | 1.56 | Anti-nociceptive and antioxidant activity of betaine on formalin- and writhing tests induced pain in mice. ( Hassanpour, S; Razavi, SM; Rezaei, H, 2020) |
| "Most drugs used to treat pain and inflammation have potential side effects, which makes it necessary to search for new sources of bioactive molecules." | 1.48 | LASSBio-1586, an N-acylhydrazone derivative, attenuates nociceptive behavior and the inflammatory response in mice. ( Alencar Filho, EB; Almeida, JRGDS; Barreiro, EJL; Diniz, TC; Lavor, ÉM; Lima, LM; Lima-Saraiva, SRG; Mendes, RL; Oliveira Júnior, RG; Silva, JC; Silva, MGE; Soares, JMD, 2018) |
| "For the neuropathic pain that was induced by a chronic constriction injury of the sciatic nerve, Phα1β and its Recombinant reduced the allodynia that was induced by the CCI procedure in the rats and the hypersensitivity lasted for 4 h." | 1.46 | The spider toxin Phα1β recombinant possesses strong analgesic activity. ( Borges, MH; Cordeiro, MN; de Castro Junior, CJ; de Oliveira Adamante, G; De Prá, SD; de Souza, AH; Ferreira, J; Gomez, MV; Milioli, AM; Rigo, FK; Santa Cecilia, FV; Silva, JF; Trevisan, G, 2017) |
| "Luteolin is a naturally occurring flavonoid with diverse pharmacological properties such as anti-inflammatory, antioxidant and anticancer." | 1.46 | Effects of luteolin and luteolin-morphine co-administration on acute and chronic pain and sciatic nerve ligated-induced neuropathy in mice. ( Abdollahzadeh, M; Golmakani, E; Hashemzaei, M; Iranshahi, M; Rezaee, R; Tabrizian, K, 2017) |
| " Concerning the emotional pain responses revealed with USVs, we assumed that the antinociceptive effects were almost completely derived from duloxetine, since celecoxib was ineffective when administered alone or reduced the dosage of duloxetine when given in combination." | 1.39 | Synergistic analgesia of duloxetine and celecoxib in the mouse formalin test: a combination analysis. ( Dong, YL; Gu, ZX; Lu, GJ; Sun, YH; Wang, W; Wang, YT; Wu, SX; Yang, J; Zhao, GL, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 50 (84.75) | 24.3611 |
| 2020's | 9 (15.25) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Z | 1 |
| Peng, YB | 2 |
| Neves, ML | 1 |
| Karvat, J | 1 |
| Simões, RR | 1 |
| Speretta, GFF | 1 |
| Lataro, RM | 1 |
| da Silva, MD | 1 |
| Santos, ARS | 1 |
| Wang, D | 1 |
| Yang, H | 1 |
| Liang, Y | 1 |
| Wang, X | 1 |
| Du, X | 1 |
| Li, R | 1 |
| Jiang, Y | 1 |
| Ye, J | 1 |
| Gaspar, JC | 1 |
| Okine, BN | 2 |
| Llorente-Berzal, A | 1 |
| Roche, M | 2 |
| Finn, DP | 2 |
| Hassanpour, S | 1 |
| Rezaei, H | 1 |
| Razavi, SM | 1 |
| Ulker, E | 1 |
| Caillaud, M | 1 |
| Patel, T | 1 |
| White, A | 1 |
| Rashid, D | 1 |
| Alqasem, M | 1 |
| Lichtman, AH | 1 |
| Bryant, CD | 1 |
| Damaj, MI | 1 |
| Xing, Y | 1 |
| Liu, Y | 1 |
| Deng, M | 1 |
| Wang, HP | 1 |
| Abdul, M | 1 |
| Zhang, FF | 1 |
| Zhang, Z | 1 |
| Cao, JL | 1 |
| Ryu, SW | 1 |
| Kim, YO | 2 |
| Kim, HB | 1 |
| Oh, SB | 1 |
| Choi, JI | 1 |
| Yoon, MH | 1 |
| Yao, L | 2 |
| Zhang, TY | 1 |
| Diao, XT | 1 |
| Ma, JJ | 1 |
| Bai, HH | 1 |
| Suo, ZW | 1 |
| Liu, YN | 1 |
| Yang, X | 2 |
| Hu, XD | 1 |
| García, G | 1 |
| Martínez-Rojas, VA | 1 |
| Murbartián, J | 1 |
| Boakye-Gyasi, E | 1 |
| Henneh, IT | 1 |
| Abotsi, WKM | 1 |
| Ameyaw, EO | 1 |
| Woode, E | 1 |
| Rigo, FK | 1 |
| Trevisan, G | 1 |
| De Prá, SD | 1 |
| Cordeiro, MN | 1 |
| Borges, MH | 1 |
| Silva, JF | 1 |
| Santa Cecilia, FV | 1 |
| de Souza, AH | 1 |
| de Oliveira Adamante, G | 1 |
| Milioli, AM | 1 |
| de Castro Junior, CJ | 1 |
| Ferreira, J | 1 |
| Gomez, MV | 1 |
| Hong, B | 1 |
| Ni, L | 1 |
| Wang, L | 1 |
| Hu, X | 1 |
| Sałat, K | 1 |
| Kołaczkowski, M | 1 |
| Furgała, A | 1 |
| Rojek, A | 1 |
| Śniecikowska, J | 1 |
| Varney, MA | 1 |
| Newman-Tancredi, A | 1 |
| Shoaib, M | 1 |
| Shah, SWA | 1 |
| Ali, N | 1 |
| Shah, I | 1 |
| Shafiullah, - | 1 |
| Ayaz, M | 1 |
| Tahir, MN | 1 |
| Akhtar, S | 1 |
| Ayub, MT | 1 |
| Zanfirescu, A | 1 |
| Cristea, AN | 1 |
| Nitulescu, GM | 1 |
| Velescu, BS | 1 |
| Gradinaru, D | 1 |
| Choi, HS | 1 |
| Lee, MJ | 2 |
| Choi, SR | 1 |
| Smeester, BA | 1 |
| Beitz, AJ | 1 |
| Lee, JH | 1 |
| Pourreza, P | 1 |
| Babapour, V | 1 |
| Haghparast, A | 1 |
| Hishe, HZ | 1 |
| Ambech, TA | 1 |
| Hiben, MG | 1 |
| Fanta, BS | 1 |
| Silva, JC | 1 |
| Oliveira Júnior, RG | 1 |
| Silva, MGE | 1 |
| Lavor, ÉM | 1 |
| Soares, JMD | 1 |
| Lima-Saraiva, SRG | 1 |
| Diniz, TC | 1 |
| Mendes, RL | 1 |
| Alencar Filho, EB | 1 |
| Barreiro, EJL | 1 |
| Lima, LM | 1 |
| Almeida, JRGDS | 1 |
| Alotaibi, G | 1 |
| Rahman, S | 1 |
| Zhang, MM | 1 |
| Ji, W | 1 |
| Pei, LY | 1 |
| Wang, W | 3 |
| Chen, T | 1 |
| Li, H | 1 |
| Zhang, T | 1 |
| Wu, SX | 2 |
| Li, YQ | 1 |
| Rios, ER | 1 |
| Rocha, NF | 1 |
| Carvalho, AM | 1 |
| Vasconcelos, LF | 1 |
| Dias, ML | 1 |
| de Sousa, DP | 2 |
| de Sousa, FC | 1 |
| Fonteles, MM | 1 |
| Godínez-Chaparro, B | 1 |
| López-Santillán, FJ | 1 |
| Argüelles, CF | 1 |
| Villalón, CM | 1 |
| Granados-Soto, V | 3 |
| García-Hernández, L | 1 |
| Navarrete-Vázquez, G | 1 |
| González-Trujano, ME | 1 |
| López-Muñoz, FJ | 1 |
| Déciga-Campos, M | 1 |
| Ren, W | 1 |
| Yuan, L | 1 |
| Li, J | 1 |
| Huang, XJ | 1 |
| Chen, S | 1 |
| Zou, DJ | 1 |
| Liu, X | 2 |
| Yang, XZ | 1 |
| Shen, F | 1 |
| Tsuruda, PR | 1 |
| Smith, JA | 1 |
| Obedencio, GP | 1 |
| Martin, WJ | 1 |
| Sun, YH | 1 |
| Dong, YL | 1 |
| Wang, YT | 1 |
| Zhao, GL | 1 |
| Lu, GJ | 1 |
| Yang, J | 1 |
| Gu, ZX | 1 |
| Desroches, J | 1 |
| Bouchard, JF | 1 |
| Gendron, L | 1 |
| Beaulieu, P | 1 |
| Lan, Y | 1 |
| Chen, Y | 1 |
| Xu, X | 1 |
| Qiu, Y | 1 |
| Liu, S | 1 |
| Liu, BF | 1 |
| Zhang, G | 1 |
| Nakama-Kitamura, M | 2 |
| Jafari, MR | 1 |
| Onsori, S | 1 |
| Fekrmandi, F | 1 |
| Tabrizian, P | 1 |
| Alipour, M | 1 |
| Zarrindast, MR | 1 |
| Barragán-Iglesias, P | 1 |
| Mendoza-Garcés, L | 1 |
| Pineda-Farias, JB | 1 |
| Solano-Olivares, V | 1 |
| Rodríguez-Silverio, J | 1 |
| Flores-Murrieta, FJ | 1 |
| Rocha-González, HI | 1 |
| Wolkers, CP | 1 |
| Barbosa Junior, A | 1 |
| Menescal-de-Oliveira, L | 1 |
| Hoffmann, A | 1 |
| Yoon, SY | 1 |
| Woo, J | 1 |
| Park, JO | 1 |
| Choi, EJ | 1 |
| Shin, HS | 1 |
| Roh, DH | 1 |
| Kim, KS | 1 |
| Jennings, EM | 1 |
| Olango, WM | 1 |
| López-Canul, M | 1 |
| Comai, S | 1 |
| Domínguez-López, S | 1 |
| Gobbi, G | 1 |
| Wang, HL | 1 |
| Li, YX | 1 |
| Niu, YT | 1 |
| Zheng, J | 2 |
| Wu, J | 1 |
| Shi, GJ | 1 |
| Ma, L | 1 |
| Niu, Y | 1 |
| Sun, T | 1 |
| Yu, JQ | 1 |
| Bohár, Z | 1 |
| Nagy-Grócz, G | 1 |
| Fejes-Szabó, A | 1 |
| Tar, L | 1 |
| László, AM | 1 |
| Büki, A | 1 |
| Szabadi, N | 1 |
| Vraukó, V | 1 |
| Vécsei, L | 1 |
| Párdutz, Á | 1 |
| Orrù, A | 1 |
| Casu, MA | 1 |
| Tambaro, S | 1 |
| Marchese, G | 1 |
| Casu, G | 1 |
| Ruiu, S | 1 |
| Jang, M | 1 |
| Choi, JH | 1 |
| Kim, EJ | 1 |
| Nah, SY | 1 |
| Kim, HJ | 1 |
| Lee, S | 1 |
| Lee, SW | 1 |
| Cho, IH | 1 |
| Parent, AJ | 1 |
| Tétreault, P | 1 |
| Roux, M | 1 |
| Belleville, K | 1 |
| Longpré, JM | 1 |
| Beaudet, N | 1 |
| Goffaux, P | 1 |
| Sarret, P | 1 |
| Mifflin, KA | 1 |
| Benson, C | 1 |
| Thorburn, KC | 1 |
| Baker, GB | 1 |
| Kerr, BJ | 1 |
| Macedo, CG | 1 |
| Fanton, LE | 1 |
| Fischer, L | 1 |
| Tambeli, CH | 1 |
| Silva, M | 1 |
| Martins, D | 1 |
| Charrua, A | 1 |
| Piscitelli, F | 1 |
| Tavares, I | 1 |
| Morgado, C | 1 |
| Di Marzo, V | 1 |
| Lu, B | 1 |
| Jiang, J | 1 |
| Sun, J | 1 |
| Xiao, C | 1 |
| Meng, B | 1 |
| Li, X | 1 |
| Wang, R | 1 |
| Wu, G | 1 |
| Chen, J | 1 |
| Barreto, RSS | 1 |
| Quintans, JSS | 1 |
| Amarante, RKL | 1 |
| Nascimento, TS | 1 |
| Amarante, RS | 1 |
| Barreto, AS | 1 |
| Pereira, EWM | 1 |
| Duarte, MC | 1 |
| Coutinho, HDM | 1 |
| Menezes, IRA | 1 |
| Zengin, G | 1 |
| Aktumsek, A | 1 |
| Quintans-Júnior, LJ | 1 |
| da Silva Brum, E | 1 |
| da Rosa Moreira, L | 1 |
| da Silva, ARH | 1 |
| Boligon, AA | 1 |
| Carvalho, FB | 1 |
| Athayde, ML | 1 |
| Brandão, R | 1 |
| Oliveira, SM | 1 |
| Li, AL | 1 |
| Chiao, JC | 1 |
| Souto-Maior, FN | 1 |
| Fonsêca, DV | 1 |
| Salgado, PR | 1 |
| Monte, LO | 1 |
| de Almeida, RN | 1 |
| Melo, LT | 1 |
| Duailibe, MA | 1 |
| Pessoa, LM | 1 |
| da Costa, FN | 1 |
| Vieira-Neto, AE | 1 |
| de Vasconcellos Abdon, AP | 1 |
| Campos, AR | 1 |
| Hashemzaei, M | 1 |
| Abdollahzadeh, M | 1 |
| Iranshahi, M | 1 |
| Golmakani, E | 1 |
| Rezaee, R | 1 |
| Tabrizian, K | 1 |
| Kitamura, Y | 1 |
| Naono-Nakayama, R | 1 |
| Sunakawa, N | 1 |
| Ikeda, T | 1 |
| Matsushima, O | 1 |
| Nishimori, T | 1 |
| Miranda, HF | 1 |
| Noriega, V | 1 |
| Zepeda, RJ | 1 |
| Sierralta, F | 1 |
| Prieto, JC | 1 |
| Ohsawa, M | 1 |
| Mutoh, J | 1 |
| Asato, M | 1 |
| Yamamoto, S | 1 |
| Ono, H | 1 |
| Hisa, H | 1 |
| Kamei, J | 1 |
| Montrucchio, DP | 1 |
| Miguel, OG | 1 |
| Zanin, SM | 1 |
| da Silva, GA | 1 |
| Cardozo, AM | 1 |
| Santos, AR | 1 |
| Kers, I | 1 |
| Csjernyik, G | 1 |
| Macsari, I | 1 |
| Nylöf, M | 1 |
| Sandberg, L | 1 |
| Skogholm, K | 1 |
| Bueters, T | 1 |
| Eriksson, AB | 1 |
| Oerther, S | 1 |
| Lund, PE | 1 |
| Venyike, E | 1 |
| Nyström, JE | 1 |
| Besidski, Y | 1 |
| Sartori, G | 1 |
| Neto, JS | 1 |
| Pesarico, AP | 1 |
| Back, DF | 1 |
| Nogueira, CW | 1 |
| Zeni, G | 1 |
59 other studies available for formaldehyde and Nociceptive Pain
| Article | Year |
|---|---|
Multi-region local field potential signatures in response to the formalin-induced inflammatory stimulus in male rats.
Topics: Amygdala; Animals; Brain Waves; Disease Models, Animal; Disinfectants; Electrophysiological Phenomen | 2022 |
The antinociceptive effect of manual acupuncture in the auricular branch of the vagus nerve in visceral and somatic acute pain models and its laterality dependence.
Topics: Acupuncture Therapy; Acute Pain; Analgesics; Animals; Cholinergic Agents; Cholinergic Antagonists; F | 2022 |
Antinociceptive Effect of Spirocyclopiperazinium Salt Compound DXL-A-24 and the Underlying Mechanism.
Topics: Acetic Acid; Analgesics; Animals; Calcitonin Gene-Related Peptide; Calcium-Calmodulin-Dependent Prot | 2019 |
Pharmacological Blockade of PPAR Isoforms Increases Conditioned Fear Responding in the Presence of Nociceptive Tone.
Topics: Analgesia; Anilides; Animals; Conditioning, Psychological; Extinction, Psychological; Fear; Formalde | 2020 |
Anti-nociceptive and antioxidant activity of betaine on formalin- and writhing tests induced pain in mice.
Topics: Analgesics; Animals; Antioxidants; Behavior, Animal; Betaine; Formaldehyde; Male; Mice; Nociceptive | 2020 |
C57BL/6 substrain differences in formalin-induced pain-like behavioral responses.
Topics: Animals; Behavior, Animal; Disinfectants; Female; Formaldehyde; Hyperalgesia; Inflammation; Male; Mi | 2020 |
The synergistic effects of opioid and neuropeptide B/W in rat acute inflammatory and neuropathic pain models.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Disease Models, Animal; Drug Synergism; Drug Therapy, | 2021 |
Antinociceptive effect of intrathecal P7C3 via GABA in a rat model of inflammatory pain.
Topics: Analgesics; Animals; Calcium Signaling; Carbazoles; Disease Models, Animal; Formaldehyde; gamma-Amin | 2021 |
Functional expression of glycine receptors in DRG neurons of mice.
Topics: Analgesics; Animals; Behavior, Animal; Disease Models, Animal; Formaldehyde; Ganglia, Spinal; Glycin | 2021 |
TREK-1 potassium channels participate in acute and long-lasting nociceptive hypersensitivity induced by formalin in rats.
Topics: Animals; Disease Models, Animal; Disinfectants; Female; Formaldehyde; Ganglia, Spinal; Hyperalgesia; | 2021 |
Hydro-ethanolic leaf extract of Ziziphus abyssinica Hochst Ex A. Rich (Rhamnaceae) exhibits anti-nociceptive effects in murine models.
Topics: Acetic Acid; Africa; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Carrageenan; D | 2017 |
The spider toxin Phα1β recombinant possesses strong analgesic activity.
Topics: Analgesics, Non-Narcotic; Animals; Calcium Channel Blockers; Capsaicin; Formaldehyde; Male; Melanoma | 2017 |
Antinociceptive effect of botulinum toxin A involves alterations in AMPA receptor expression and glutamate release in spinal dorsal horn neurons.
Topics: Analgesics, Non-Narcotic; Animals; Axonal Transport; Botulinum Toxins, Type A; Cell Membrane; Cells, | 2017 |
Antinociceptive, antiallodynic and antihyperalgesic effects of the 5-HT
Topics: Analgesics; Animals; Antineoplastic Agents; Cyclohexanes; Diabetic Neuropathies; Disease Models, Ani | 2017 |
Synthesis, antinociceptive activity and structure activity relationship of flavone derivatives.
Topics: Acetic Acid; Analgesics; Animals; Behavior, Animal; Disease Models, Animal; Flavones; Formaldehyde; | 2017 |
Chronic Monosodium Glutamate Administration Induced Hyperalgesia in Mice.
Topics: Animals; Behavior, Animal; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Adm | 2017 |
Spinal Sigma-1 Receptor-mediated Dephosphorylation of Astrocytic Aromatase Plays a Key Role in Formalin-induced Inflammatory Nociception.
Topics: Animals; Aromatase; Aromatase Inhibitors; Astrocytes; Calcineurin; Formaldehyde; Glial Fibrillary Ac | 2018 |
Role of dorsal hippocampal orexin-1 receptors in modulation of antinociception induced by chemical stimulation of the lateral hypothalamus.
Topics: Analgesics; Animals; Benzoxazoles; CA1 Region, Hippocampal; Carbachol; Catheters, Indwelling; Cholin | 2018 |
Anti-nociceptive effect of methanol extract of leaves of Senna singueana in mice.
Topics: Acetic Acid; Analgesics; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationsh | 2018 |
LASSBio-1586, an N-acylhydrazone derivative, attenuates nociceptive behavior and the inflammatory response in mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Carrage | 2018 |
Effects of glial glutamate transporter activator in formalin-induced pain behaviour in mice.
Topics: Animals; Astrocytes; Behavior, Animal; Excitatory Amino Acid Transporter 2; Extracellular Signal-Reg | 2019 |
Acute colitis induces neurokinin 1 receptor internalization in the rat lumbosacral spinal cord.
Topics: Acute Disease; Animals; Colitis; Colon; Formaldehyde; Gene Expression; Lumbosacral Region; Male; Neu | 2013 |
TRP and ASIC channels mediate the antinociceptive effect of citronellyl acetate.
Topics: Acetic Acid; Acid Sensing Ion Channels; Acute Pain; Administration, Oral; Analgesics; Animals; Disea | 2013 |
Role of 5-HT₁B/₁D receptors in the reduction of formalin-induced nociception and secondary allodynia/hyperalgesia produced by antimigraine drugs in rats.
Topics: Acute Pain; Animals; Biphenyl Compounds; Chronic Pain; Dihydroergotamine; Disease Models, Animal; Dr | 2013 |
Antihyperalgesic activity of a novel synthesized analogue of lidocaine in diabetic rats.
Topics: Amines; Analgesics; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Diabetes Complications; | 2013 |
Ethanolic extract of Aconiti Brachypodi Radix attenuates nociceptive pain probably via inhibition of voltage-dependent Na⁺ channel.
Topics: Acetic Acid; Aconitum; Analgesics; Animals; Dinoprostone; Disease Models, Animal; Dose-Response Rela | 2012 |
Relative contributions of norepinephrine and serotonin transporters to antinociceptive synergy between monoamine reuptake inhibitors and morphine in the rat formalin model.
Topics: Analgesia; Animals; Atomoxetine Hydrochloride; Biogenic Monoamines; Chromatography, Liquid; Drug Syn | 2013 |
Synergistic analgesia of duloxetine and celecoxib in the mouse formalin test: a combination analysis.
Topics: Analgesics; Analysis of Variance; Animals; Celecoxib; Cyclooxygenase 2 Inhibitors; Dose-Response Rel | 2013 |
Involvement of cannabinoid receptors in peripheral and spinal morphine analgesia.
Topics: Analgesics, Opioid; Animals; Edema; Formaldehyde; Hindlimb; Hot Temperature; Injections, Intradermal | 2014 |
Synthesis and biological evaluation of a novel sigma-1 receptor antagonist based on 3,4-dihydro-2(1H)-quinolinone scaffold as a potential analgesic.
Topics: Analgesics; Animals; Brain; Dose-Response Relationship, Drug; Formaldehyde; Guinea Pigs; Hydroquinon | 2014 |
The distinctive significance of analgesic drugs and olfactory stimulants on learned pain in mice.
Topics: Acetaminophen; Amines; Analgesics; Animals; Conditioning, Psychological; Cyclohexanecarboxylic Acids | 2014 |
Influence of muscarinic receptor modulators on interacerebroventricular injection of arachydonylcyclopropylamide induced antinociception in mice.
Topics: Analgesics, Non-Narcotic; Animals; Arachidonic Acids; Atropine; Cannabinoid Receptor Agonists; Cathe | 2015 |
Participation of peripheral P2Y1, P2Y6 and P2Y11 receptors in formalin-induced inflammatory pain in rats.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Female; Formaldehyde; Ganglia, Spinal; Infla | 2015 |
Acute administration of a cannabinoid CB1 receptor antagonist impairs stress-induced antinociception in fish.
Topics: Animal Fins; Animals; Cannabinoid Receptor Antagonists; Fish Proteins; Fishes; Formaldehyde; Motor A | 2015 |
Intrathecal RGS4 inhibitor, CCG50014, reduces nociceptive responses and enhances opioid-mediated analgesic effects in the mouse formalin test.
Topics: Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Rel | 2015 |
Repeated forced swim stress differentially affects formalin-evoked nociceptive behaviour and the endocannabinoid system in stress normo-responsive and stress hyper-responsive rat strains.
Topics: Amygdala; Animals; Disease Models, Animal; Endocannabinoids; Formaldehyde; Functional Laterality; Ge | 2016 |
Antinociceptive properties of selective MT(2) melatonin receptor partial agonists.
Topics: Acetamides; Acetaminophen; Analgesics; Aniline Compounds; Animals; Behavior, Animal; Brain; Disease | 2015 |
Observing Anti-inflammatory and Anti-nociceptive Activities of Glycyrrhizin Through Regulating COX-2 and Pro-inflammatory Cytokines Expressions in Mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Capillary Permeability; Carrageenan; Cyc | 2015 |
Diverse effects of Brilliant Blue G administration in models of trigeminal activation in the rat.
Topics: Analgesics, Non-Narcotic; Animals; Calcitonin Gene-Related Peptide; Disease Models, Animal; Drug Eva | 2015 |
Withania somnifera (L.) Dunal root extract alleviates formalin-induced nociception in mice: involvement of the opioidergic system.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; For | 2016 |
Ginsenoside Rb1 Attenuates Acute Inflammatory Nociception by Inhibition of Neuronal ERK Phosphorylation by Regulation of the Nrf2 and NF-κB Pathways.
Topics: Analgesics; Animals; Astrocytes; Disease Models, Animal; Dose-Response Relationship, Drug; Extracell | 2016 |
Descending nociceptive inhibition is modulated in a time-dependent manner in a double-hit model of chronic/tonic pain.
Topics: Animals; Chromatography, Liquid; Chronic Pain; Disease Models, Animal; Formaldehyde; Hyperalgesia; M | 2016 |
Manipulation of Neurotransmitter Levels Has Differential Effects on Formalin-Evoked Nociceptive Behavior in Male and Female Mice.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Biphenyl Compounds; Castration; Estrous Cycle; Fem | 2016 |
Coactivation of μ- and κ-Opioid Receptors May Mediate the Protective Effect of Testosterone on the Development of Temporomandibular Joint Nociception in Male Rats.
Topics: Animals; Brain Stem; Facial Pain; Formaldehyde; Male; Naloxone; Naltrexone; Narcotic Antagonists; No | 2016 |
Endovanilloid control of pain modulation by the rostroventromedial medulla in an animal model of diabetic neuropathy.
Topics: Amides; Amidohydrolases; Analgesics, Non-Narcotic; Animals; Arachidonic Acids; Capsaicin; Chronic Pa | 2016 |
Inhibition of mammalian target of rapamycin activation in the rostral anterior cingulate cortex attenuates pain-related aversion in rats.
Topics: Analgesics; Animals; Avoidance Learning; Emotions; Formaldehyde; Gyrus Cinguli; Inflammation; Male; | 2016 |
Evidence for the involvement of TNF-α and IL-1β in the antinociceptive and anti-inflammatory activity of Stachys lavandulifolia Vahl. (Lamiaceae) essential oil and (-)-α-bisabolol, its main compound, in mice.
Topics: Analgesics; Animals; Anti-Infective Agents; Capsaicin; Carrageenan; Disease Models, Animal; Dose-Res | 2016 |
Tabernaemontana catharinensis ethyl acetate fraction presents antinociceptive activity without causing toxicological effects in mice.
Topics: Acetates; Acetic Acid; Administration, Oral; Analgesics; Animals; Apocynaceae; Behavior, Animal; Cap | 2016 |
Reduced local field potential power in the medial prefrontal cortex by noxious stimuli.
Topics: Alpha Rhythm; Animals; Beta Rhythm; Cortical Synchronization; Formaldehyde; Hindlimb; Male; Microele | 2016 |
Antinociceptive and anticonvulsant effects of the monoterpene linalool oxide.
Topics: Acetic Acid; Acyclic Monoterpenes; Analgesics; Animals; Anticonvulsants; Behavior, Animal; Cyclohexa | 2017 |
(-)-α-Bisabolol reduces orofacial nociceptive behavior in rodents.
Topics: Acrolein; Administration, Oral; Administration, Topical; Analgesics; Animals; Behavior, Animal; Bind | 2017 |
Effects of luteolin and luteolin-morphine co-administration on acute and chronic pain and sciatic nerve ligated-induced neuropathy in mice.
Topics: Acute Disease; Analgesics; Animals; Chronic Pain; Disease Models, Animal; Drug Therapy, Combination; | 2017 |
A novel conditioned nociceptive response in mice.
Topics: Acoustic Stimulation; Adjuvants, Anesthesia; Analysis of Variance; Animals; Conditioning, Classical; | 2011 |
Pharmacological characteristics of endokinin C/D-derived peptides in nociceptive and inflammatory processing in rats.
Topics: Amino Acid Sequence; Amino Acids; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; C | 2011 |
Synergism between fentanyl and tramadol in tonic inflammatory pain: the orofacial formalin test.
Topics: Analgesics; Animals; Drug Synergism; Facial Pain; Fentanyl; Formaldehyde; Inflammation; Male; Mice; | 2012 |
Carnosine has antinociceptive properties in the inflammation-induced nociceptive response in mice.
Topics: Acetic Acid; Analgesics; Animals; Carnosine; Formaldehyde; Gene Expression Regulation; Inflammation; | 2012 |
Antinociceptive effects of a chloroform extract and the alkaloid dicentrine isolated from fruits of Ocotea puberula.
Topics: Acetic Acid; Alkaloids; Analgesics, Opioid; Animals; Aporphines; Chloroform; Dose-Response Relations | 2012 |
Structure and activity relationship in the (S)-N-chroman-3-ylcarboxamide series of voltage-gated sodium channel blockers.
Topics: Analgesics; Animals; Chromans; Formaldehyde; Humans; NAV1.7 Voltage-Gated Sodium Channel; Nociceptiv | 2012 |
Bis-vinyl selenides obtained via iron(III) catalyzed addition of PhSeSePh to alkynes: synthesis and antinociceptive activity.
Topics: Alkynes; Analgesics; Animals; Catalysis; Chlorides; Dose-Response Relationship, Drug; Edema; Ferric | 2013 |