formaldehyde has been researched along with Neuralgia in 80 studies
paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy
Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tolerance to morphine analgesia following repeated administration disturbs the continuation of opioid therapy for severe pain." | 7.78 | Inhibition of morphine tolerance is mediated by painful stimuli via central mechanisms. ( Fukazawa, Y; Iwai, S; Kiguchi, N; Kishioka, S; Kobayashi, Y; Saika, F; Ueno, K; Yamamoto, C, 2012) |
| "Drug effects on formalin-induced mechanical allodynia were evaluated for comparison." | 5.43 | Pharmacological modulation of neuropathic pain-related depression of behavior: effects of morphine, ketoprofen, bupropion and [INCREMENT]9-tetrahydrocannabinol on formalin-induced depression of intracranial self-stimulation in rats. ( Leitl, MD; Negus, SS, 2016) |
| " Nociceptive response induced by formaldehyde and mechanical allodynia induced by chronic constriction injury (CCI) of the sciatic nerve or intraplantar (ipl) injection of complete Freund's adjuvant (CFA) were used as experimental models of pain." | 3.91 | The phthalimide analogues N-3-hydroxypropylphthalimide and N-carboxymethyl-3-nitrophthalimide exhibit activity in experimental models of inflammatory and neuropathic pain. ( Alves, RJ; Araújo, DP; Batista, CRA; Brito, AMS; Canhestro, WG; Coelho, MM; Coura, GME; de Fátima, Â; Dutra, MMGB; Godin, AM; Machado, RR; Matsui, TC; Melo, ISF, 2019) |
| "Curcumin, the active ingredient of turmeric (Curcuma longa), has a wide range of beneficial effects including anti-inflammation and analgesia." | 3.79 | Antinociceptive curcuminoid, KMS4034, effects on inflammatory and neuropathic pain likely via modulating TRPV1 in mice. ( Choi, JM; Chung, HJ; Han, H; Jung, SJ; Kim, HJ; Lee, JY; Lee, YS; Oh, Y; Seo, KS; Shin, KJ; Shin, TJ; Yoon, TG, 2013) |
| "Tolerance to morphine analgesia following repeated administration disturbs the continuation of opioid therapy for severe pain." | 3.78 | Inhibition of morphine tolerance is mediated by painful stimuli via central mechanisms. ( Fukazawa, Y; Iwai, S; Kiguchi, N; Kishioka, S; Kobayashi, Y; Saika, F; Ueno, K; Yamamoto, C, 2012) |
| " In an inflammatory pain model, Compound 5 suppressed the capsaicin-induced flinching behavior in a dose-dependent manner." | 3.77 | Suppressive effects of glycyrrhetinic acid derivatives on tachykinin receptor activation and hyperalgesia. ( Akasaka, Y; Hatta, A; Inoue, H; Sakai, A; Suzuki, H; Takasu, K; Tsukahara, M, 2011) |
| " In this study, we investigated the effects of M58373 on substance P release from sensory neurons in vitro and pain behaviors/responses in rats, compared with mexiletine." | 3.73 | Potent analgesic effects of a putative sodium channel blocker M58373 on formalin-induced and neuropathic pain in rats. ( Akada, Y; Amano, K; Fukudome, Y; Itoh, M; Ogawa, S; Yamamoto, I; Yamasaki, F, 2006) |
| "Ifenprodil was administered in PDN rats while saline was administered intrathecally in the control group." | 1.62 | Ifenprodil Reduced Expression of Activated Microglia, BDNF and DREAM Proteins in the Spinal Cord Following Formalin Injection During the Early Stage of Painful Diabetic Neuropathy in Rats. ( Ab Aziz, CB; Ismail, CAN; Long, I; Suppian, R, 2021) |
| "The complications of diabetic polyneuropathy (DN) determines its level of severity." | 1.56 | Expressions of spinal microglia activation, BDNF, and DREAM proteins correlated with formalin-induced nociceptive responses in painful and painless diabetic neuropathy rats. ( Ab Aziz, CB; Ismail, CAN; Long, I; Suppian, R, 2020) |
| "For the neuropathic pain that was induced by a chronic constriction injury of the sciatic nerve, Phα1β and its Recombinant reduced the allodynia that was induced by the CCI procedure in the rats and the hypersensitivity lasted for 4 h." | 1.46 | The spider toxin Phα1β recombinant possesses strong analgesic activity. ( Borges, MH; Cordeiro, MN; de Castro Junior, CJ; de Oliveira Adamante, G; De Prá, SD; de Souza, AH; Ferreira, J; Gomez, MV; Milioli, AM; Rigo, FK; Santa Cecilia, FV; Silva, JF; Trevisan, G, 2017) |
| "Sinomenine, which is a main bioactive ingredient in Sinomenium acutum, has been reported to have an analgesic effect in diverse pain animal models." | 1.46 | Sinomenine produces peripheral analgesic effects via inhibition of voltage-gated sodium currents. ( Kang, Y; Kim, HB; Lee, JY; Oh, SB; Won, J; Yoon, SY, 2017) |
| "Drug effects on formalin-induced mechanical allodynia were evaluated for comparison." | 1.43 | Pharmacological modulation of neuropathic pain-related depression of behavior: effects of morphine, ketoprofen, bupropion and [INCREMENT]9-tetrahydrocannabinol on formalin-induced depression of intracranial self-stimulation in rats. ( Leitl, MD; Negus, SS, 2016) |
| "In paclitaxel-treated mice, they did not attenuate heat hyperalgesia but N-(3-aminopropyl)-2-{[(3-methylphenyl)methyl]oxy}-N-(2-thienylmethyl) benzamide hydrochloride salt (AMTB), a TRPM8 antagonist, reduced cold hyperalgesia and tactile allodynia by 31% (P<0." | 1.42 | Antinociceptive activity of transient receptor potential channel TRPV1, TRPA1, and TRPM8 antagonists in neurogenic and neuropathic pain models in mice. ( Filipek, B; Sałat, K, 2015) |
| "NRG-1 inhibits neuropathic pain after SNI in a dose-dependent manner, while NRG-1 aggravates formalin-induced neuropathic pain." | 1.40 | Distinct roles of neuregulin in different models of neuropathic pain. ( Chen, X; Dai, DW; Deng, ZF; Lu, YM; Xu, Z; Yuan, L; Zhang, AJ; Zhang, PQ, 2014) |
| "However, orofacial heat and cold hyperalgesia, induced by carrageenan injected into the upper lip (50 µg/50 μl), was abolished by previous intraganglionar RTX treatment." | 1.40 | Intraganglionar resiniferatoxin prevents orofacial inflammatory and neuropathic hyperalgesia. ( Chichorro, JG; Cruz, LS; Kopruszinski, CM, 2014) |
| "OVX rats developed thermal hyperalgesia in proximal and distal tail that was established 2 weeks after OVX and lasted the 7 weeks of the experiment." | 1.40 | Ovariectomy results in variable changes in nociception, mood and depression in adult female rats. ( Li, LH; Wang, ZC; Yu, J; Zhang, YQ, 2014) |
| "Peripheral nerve injury can result in neuropathic pain, a chronic condition of unclear cause often poorly responsive to current treatments." | 1.40 | Upregulation of neuregulin-1 reverses signs of neuropathic pain in rats. ( Chen, X; Dai, D; Lu, Y; Wang, G; Yuan, L; Zhang, A; Zhang, P, 2014) |
| "When morphine was co-administered with formalin, it exhibited similar peripheral antinociception at both lateral and medial sites, and following sham or SNI surgery." | 1.37 | Reduction of formalin-evoked responses and maintenance of peripheral antinociception by morphine against formalin in the spared nerve injury model. ( Reid, AR; Sawynok, J, 2011) |
| "1) In vivo bioavailability study: TC-2559 (3 mg/kg) had high absorption rate in rats with maximal total brain concentration reached over 4." | 1.37 | Enhanced inhibitory synaptic transmission in the spinal dorsal horn mediates antinociceptive effects of TC-2559. ( Cheng, LZ; Fan, J; Han, L; Huang, LT; Peng, LC; Wang, Y, 2011) |
| "Moreover, in two neuropathic pain models induced by chronic constriction and spared nerve injury, KST5468 significantly increased the mechanical pain threshold." | 1.36 | KST5468, a new T-type calcium channel antagonist, has an antinociceptive effect on inflammatory and neuropathic pain models. ( Choo, H; Chung, HJ; Kim, HJ; Koh, HY; Lee, JE; Lee, MJ; Lee, SC; Pae, AN; Shin, TJ, 2010) |
| "The status of neuropathic pain alters the responsiveness to formalin injection in rats." | 1.34 | Altered response to formalin by L5 spinal nerve ligation in rats: a behavioral and molecular study. ( Itano, Y; Kaku, R; Kobayashi, H; Matsuoka, Y; Mizobuchi, S; Morita, K; Sato, T; Yokoyama, M, 2007) |
| "Neuropathic pain was induced by either ligation of left L5/L6 spinal nerves or administration of streptozotocin (50 mg/kg, i." | 1.33 | Benfotiamine relieves inflammatory and neuropathic pain in rats. ( Caram-Salas, NL; Granados-Soto, V; Medina-Santillán, R; Reyes-García, G; Rocha-González, HI; Sánchez-Ramírez, GM; Vidal-Cantú, GC, 2006) |
| "However, they attenuated hyperalgesia in several nociceptive models associated with spinal sensitization including direct spinal activation (intrathecal substance P) and peripheral tissue inflammation (intraplantar formalin or carrageenan)." | 1.32 | Activation of p38 mitogen-activated protein kinase in spinal microglia is a critical link in inflammation-induced spinal pain processing. ( Calcutt, NA; Campana, WM; Catalano, R; Feng, Y; Freshwater, JD; Marsala, M; Protter, AA; Scott, B; Svensson, CI; Westerlund, A; Yaksh, TL, 2003) |
| " Repeated intraperitoneal injections were, therefore, chosen as the dosing regimen." | 1.32 | Specific Inhibition of IkappaB kinase reduces hyperalgesia in inflammatory and neuropathic pain models in rats. ( Geisslinger, G; Gühring, H; Kunz, S; Michaelis, M; Niederberger, E; Ritzeler, O; Schmidt, R; Tegeder, I, 2004) |
| "There was no corresponding thermal hyperalgesia adjacent to the injured sciatic nerve." | 1.30 | Submodality-selective hyperalgesia adjacent to partially injured sciatic nerve in the rat is dependent on capsaicin-sensitive afferent fibers and independent of collateral sprouting or a dorsal root reflex. ( Mansikka, H; Pertovaara, A, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (2.50) | 18.7374 |
| 1990's | 2 (2.50) | 18.2507 |
| 2000's | 12 (15.00) | 29.6817 |
| 2010's | 49 (61.25) | 24.3611 |
| 2020's | 15 (18.75) | 2.80 |
| Authors | Studies |
|---|---|
| Xiong, J | 2 |
| Zhuang, T | 1 |
| Ma, Y | 1 |
| Xu, J | 1 |
| Ye, J | 2 |
| Ma, R | 1 |
| Zhang, S | 1 |
| Liu, X | 4 |
| Liu, BF | 3 |
| Hao, C | 2 |
| Zhang, G | 3 |
| Chen, Y | 3 |
| Gu, N | 1 |
| Yi, MH | 1 |
| Murugan, M | 1 |
| Xie, M | 2 |
| Parusel, S | 1 |
| Peng, J | 1 |
| Eyo, UB | 1 |
| Hunt, CL | 1 |
| Dong, H | 1 |
| Wu, LJ | 1 |
| Wang, W | 1 |
| Wang, Q | 1 |
| Huang, J | 1 |
| Li, H | 1 |
| Li, F | 1 |
| Li, X | 2 |
| Liu, R | 1 |
| Xu, M | 1 |
| Chen, J | 1 |
| Mao, Y | 1 |
| Ma, L | 1 |
| Jabbari, S | 1 |
| Abed, DZ | 1 |
| Zakaria, ZA | 1 |
| Mohammadi, S | 1 |
| García, G | 1 |
| Noriega-Navarro, R | 1 |
| Martínez-Rojas, VA | 1 |
| Gutiérrez-Lara, EJ | 1 |
| Oviedo, N | 1 |
| Murbartián, J | 1 |
| Batista, CRA | 1 |
| Godin, AM | 1 |
| Melo, ISF | 1 |
| Coura, GME | 1 |
| Matsui, TC | 1 |
| Dutra, MMGB | 1 |
| Brito, AMS | 1 |
| Canhestro, WG | 1 |
| Alves, RJ | 1 |
| Araújo, DP | 1 |
| de Fátima, Â | 1 |
| Machado, RR | 1 |
| Coelho, MM | 1 |
| Wang, D | 1 |
| Yang, H | 1 |
| Liang, Y | 1 |
| Wang, X | 1 |
| Du, X | 1 |
| Li, R | 1 |
| Jiang, Y | 1 |
| Wang, N | 1 |
| Wang, J | 2 |
| Luo, F | 1 |
| Rapacz, A | 1 |
| Rybka, S | 1 |
| Obniska, J | 1 |
| Jodłowska, A | 1 |
| Góra, M | 1 |
| Koczurkiewicz, P | 1 |
| Pękala, E | 1 |
| Siwek, A | 1 |
| Filipek, B | 2 |
| Ismail, CAN | 2 |
| Suppian, R | 2 |
| Ab Aziz, CB | 2 |
| Long, I | 2 |
| Selley, DE | 1 |
| Lazenka, MF | 1 |
| Sim-Selley, LJ | 1 |
| Secor McVoy, JR | 1 |
| Potter, DN | 1 |
| Chartoff, EH | 1 |
| Carlezon, WA | 1 |
| Negus, SS | 2 |
| Yin, X | 1 |
| Jing, Y | 1 |
| Chen, Q | 1 |
| Abbas, AB | 1 |
| Hu, J | 1 |
| Xu, H | 1 |
| Jin, J | 1 |
| Gao, L | 1 |
| Wang, ZY | 1 |
| Han, QQ | 1 |
| Deng, MY | 1 |
| Zhao, MJ | 1 |
| Apryani, E | 1 |
| Shoaib, RM | 1 |
| Wei, DQ | 1 |
| Wang, YX | 1 |
| Wang, Y | 6 |
| Li, CM | 1 |
| Han, R | 1 |
| Wang, ZZ | 1 |
| Gao, YL | 1 |
| Zhu, XY | 1 |
| Yu, X | 1 |
| Du, GY | 1 |
| Wang, HB | 1 |
| Tian, JW | 1 |
| Fu, FH | 1 |
| Tello-García, IA | 1 |
| Pérez-Ortega, J | 1 |
| Martínez-Lorenzana, G | 1 |
| González-Hernández, A | 1 |
| Condés-Lara, M | 1 |
| Cortés-Montero, E | 1 |
| Rodríguez-Muñoz, M | 1 |
| Ruiz-Cantero, MDC | 1 |
| Cobos, EJ | 1 |
| Sánchez-Blázquez, P | 1 |
| Garzón-Niño, J | 1 |
| Niu, HL | 1 |
| Liu, YN | 1 |
| Xue, DQ | 1 |
| Dong, LY | 1 |
| Liu, HJ | 1 |
| Zheng, YL | 1 |
| Zou, AR | 1 |
| Shao, LM | 1 |
| Wang, K | 1 |
| Rigo, FK | 1 |
| Trevisan, G | 1 |
| De Prá, SD | 1 |
| Cordeiro, MN | 1 |
| Borges, MH | 1 |
| Silva, JF | 1 |
| Santa Cecilia, FV | 1 |
| de Souza, AH | 1 |
| de Oliveira Adamante, G | 1 |
| Milioli, AM | 1 |
| de Castro Junior, CJ | 1 |
| Ferreira, J | 1 |
| Gomez, MV | 1 |
| Lee, JY | 2 |
| Yoon, SY | 1 |
| Won, J | 1 |
| Kim, HB | 1 |
| Kang, Y | 1 |
| Oh, SB | 1 |
| Sałat, K | 2 |
| Kołaczkowski, M | 1 |
| Furgała, A | 1 |
| Rojek, A | 1 |
| Śniecikowska, J | 1 |
| Varney, MA | 1 |
| Newman-Tancredi, A | 1 |
| Dos Santos, NM | 1 |
| Pereira, NC | 1 |
| de Albuquerque, APS | 1 |
| Dias Viegas, FP | 1 |
| Veloso, C | 1 |
| Vilela, FC | 1 |
| Giusti-Paiva, A | 1 |
| da Silva, ML | 1 |
| da Silva, JRT | 1 |
| Viegas, C | 1 |
| Wang, H | 1 |
| Charpin-El Hamri, G | 1 |
| Ye, H | 1 |
| Fussenegger, M | 1 |
| Shin, TJ | 2 |
| Choi, JM | 1 |
| Seo, KS | 1 |
| Kim, HJ | 2 |
| Yoon, TG | 1 |
| Lee, YS | 1 |
| Han, H | 1 |
| Chung, HJ | 2 |
| Oh, Y | 1 |
| Jung, SJ | 1 |
| Shin, KJ | 1 |
| Li, K | 1 |
| Tan, YH | 1 |
| Light, AR | 1 |
| Fu, KY | 1 |
| Dai, DW | 1 |
| Xu, Z | 1 |
| Chen, X | 2 |
| Yuan, L | 2 |
| Zhang, AJ | 1 |
| Zhang, PQ | 1 |
| Lu, YM | 1 |
| Deng, ZF | 1 |
| Liu, Y | 2 |
| Wu, Z | 1 |
| Tang, D | 2 |
| Xun, X | 2 |
| Liu, L | 1 |
| Nie, D | 1 |
| Xiang, Y | 1 |
| Yi, J | 3 |
| Kuki, F | 1 |
| Sugiyo, S | 1 |
| Abe, T | 1 |
| Niwa, H | 1 |
| Takemura, M | 1 |
| Demeule, M | 1 |
| Beaudet, N | 1 |
| Régina, A | 1 |
| Besserer-Offroy, É | 1 |
| Murza, A | 1 |
| Tétreault, P | 1 |
| Belleville, K | 1 |
| Ché, C | 1 |
| Larocque, A | 1 |
| Thiot, C | 1 |
| Béliveau, R | 1 |
| Longpré, JM | 1 |
| Marsault, É | 1 |
| Leduc, R | 1 |
| Lachowicz, JE | 1 |
| Gonias, SL | 1 |
| Castaigne, JP | 1 |
| Sarret, P | 1 |
| Berta, T | 1 |
| Park, CK | 1 |
| Xu, ZZ | 1 |
| Xie, RG | 1 |
| Liu, T | 1 |
| Lü, N | 1 |
| Liu, YC | 1 |
| Ji, RR | 1 |
| Cruz, LS | 1 |
| Kopruszinski, CM | 1 |
| Chichorro, JG | 1 |
| Li, LH | 1 |
| Wang, ZC | 1 |
| Yu, J | 1 |
| Zhang, YQ | 1 |
| Nishijima, CM | 1 |
| Ganev, EG | 1 |
| Mazzardo-Martins, L | 1 |
| Martins, DF | 1 |
| Rocha, LR | 1 |
| Santos, AR | 1 |
| Hiruma-Lima, CA | 1 |
| Tang, J | 1 |
| Zhang, Y | 2 |
| Peng, D | 1 |
| Liu, Z | 1 |
| Shi, X | 1 |
| Wang, G | 1 |
| Dai, D | 1 |
| Zhang, A | 1 |
| Lu, Y | 1 |
| Zhang, P | 1 |
| Park, KD | 1 |
| Yang, XF | 1 |
| Dustrude, ET | 1 |
| Ripsch, MS | 1 |
| White, FA | 1 |
| Khanna, R | 1 |
| Kohn, H | 2 |
| Bagdas, D | 1 |
| AlSharari, SD | 1 |
| Freitas, K | 1 |
| Tracy, M | 1 |
| Damaj, MI | 1 |
| Han, P | 1 |
| Liu, S | 1 |
| Zhang, M | 1 |
| Zhao, J | 1 |
| Wu, G | 1 |
| Mi, W | 1 |
| Curto-Reyes, V | 1 |
| Kirschmann, G | 1 |
| Pertin, M | 1 |
| Drexler, SK | 1 |
| Decosterd, I | 1 |
| Suter, MR | 1 |
| Syhr, KMJ | 1 |
| Boosen, M | 1 |
| Hohmann, SW | 1 |
| Longen, S | 1 |
| Köhler, Y | 1 |
| Pfeilschifter, J | 1 |
| Beck, KF | 1 |
| Geisslinger, G | 3 |
| Schmidtko, A | 1 |
| Kallenborn-Gerhardt, W | 1 |
| Zhou, XL | 1 |
| Zhang, CJ | 1 |
| Wang, M | 1 |
| Sun, LH | 1 |
| Yu, LN | 1 |
| Cao, JL | 1 |
| Yan, M | 1 |
| Leitl, MD | 1 |
| Cao, X | 1 |
| Lan, Y | 1 |
| Zhang, J | 1 |
| Xu, X | 1 |
| Qiu, Y | 1 |
| Zhao, S | 1 |
| Kang, DW | 1 |
| Moon, JY | 1 |
| Choi, JG | 1 |
| Kang, SY | 1 |
| Ryu, Y | 1 |
| Park, JB | 1 |
| Lee, JH | 1 |
| Kim, HW | 1 |
| Huang, YH | 1 |
| Hou, SY | 1 |
| Cheng, JK | 1 |
| Wu, CH | 1 |
| Lin, CR | 1 |
| Salinas-Abarca, AB | 1 |
| Avila-Rojas, SH | 1 |
| Barragán-Iglesias, P | 1 |
| Pineda-Farias, JB | 1 |
| Granados-Soto, V | 3 |
| Nikai, T | 1 |
| Basbaum, AI | 1 |
| Ahn, AH | 1 |
| Lee, MJ | 1 |
| Lee, JE | 1 |
| Choo, H | 1 |
| Koh, HY | 1 |
| Pae, AN | 1 |
| Lee, SC | 1 |
| Wijnvoord, N | 1 |
| Albuquerque, B | 1 |
| Häussler, A | 1 |
| Myrczek, T | 1 |
| Popp, L | 1 |
| Tegeder, I | 2 |
| Sawynok, J | 1 |
| Reid, AR | 1 |
| King, AM | 1 |
| Salomé, C | 1 |
| Dinsmore, J | 1 |
| Salomé-Grosjean, E | 1 |
| De Ryck, M | 1 |
| Kaminski, R | 1 |
| Valade, A | 1 |
| Cheng, LZ | 1 |
| Han, L | 1 |
| Fan, J | 1 |
| Huang, LT | 1 |
| Peng, LC | 1 |
| Holtman, JR | 1 |
| Dwoskin, LP | 1 |
| Dowell, C | 1 |
| Wala, EP | 1 |
| Zhang, Z | 1 |
| Crooks, PA | 1 |
| McIntosh, JM | 1 |
| Akasaka, Y | 1 |
| Sakai, A | 1 |
| Takasu, K | 1 |
| Tsukahara, M | 1 |
| Hatta, A | 1 |
| Suzuki, H | 1 |
| Inoue, H | 1 |
| Liu, M | 1 |
| Shen, J | 1 |
| Liu, H | 1 |
| Xu, Y | 1 |
| Su, YP | 1 |
| Yang, J | 1 |
| Yu, CX | 1 |
| Munro, G | 1 |
| Storm, A | 1 |
| Hansen, MK | 1 |
| Dyhr, H | 1 |
| Marcher, L | 1 |
| Erichsen, HK | 1 |
| Sheykhzade, M | 1 |
| Covaceuszach, S | 1 |
| Marinelli, S | 1 |
| Krastanova, I | 1 |
| Ugolini, G | 1 |
| Pavone, F | 1 |
| Lamba, D | 1 |
| Cattaneo, A | 1 |
| Romero, L | 1 |
| Zamanillo, D | 1 |
| Nadal, X | 1 |
| Sánchez-Arroyos, R | 1 |
| Rivera-Arconada, I | 1 |
| Dordal, A | 1 |
| Montero, A | 1 |
| Muro, A | 1 |
| Bura, A | 1 |
| Segalés, C | 1 |
| Laloya, M | 1 |
| Hernández, E | 1 |
| Portillo-Salido, E | 1 |
| Escriche, M | 1 |
| Codony, X | 1 |
| Encina, G | 1 |
| Burgueño, J | 1 |
| Merlos, M | 1 |
| Baeyens, JM | 1 |
| Giraldo, J | 1 |
| López-García, JA | 1 |
| Maldonado, R | 1 |
| Plata-Salamán, CR | 1 |
| Vela, JM | 1 |
| Iwai, S | 1 |
| Kiguchi, N | 1 |
| Kobayashi, Y | 1 |
| Fukazawa, Y | 1 |
| Saika, F | 1 |
| Ueno, K | 1 |
| Yamamoto, C | 1 |
| Kishioka, S | 1 |
| Coste, O | 1 |
| Möser, CV | 1 |
| Sisignano, M | 1 |
| Kynast, KL | 1 |
| Minden, A | 1 |
| Niederberger, E | 2 |
| Yamada, T | 1 |
| Zuo, D | 1 |
| Yamamoto, T | 2 |
| Olszewski, RT | 1 |
| Bzdega, T | 2 |
| Moffett, JR | 1 |
| Neale, JH | 2 |
| Cibert-Goton, V | 1 |
| Yuan, G | 1 |
| Battaglia, A | 1 |
| Fredriksson, S | 1 |
| Henkemeyer, M | 1 |
| Sears, T | 1 |
| Gavazzi, I | 1 |
| Luongo, L | 1 |
| Guida, F | 1 |
| Boccella, S | 1 |
| Bellini, G | 1 |
| Gatta, L | 1 |
| Rossi, F | 1 |
| de Novellis, V | 1 |
| Maione, S | 1 |
| Svensson, CI | 1 |
| Marsala, M | 1 |
| Westerlund, A | 1 |
| Calcutt, NA | 1 |
| Campana, WM | 1 |
| Freshwater, JD | 1 |
| Catalano, R | 1 |
| Feng, Y | 1 |
| Protter, AA | 1 |
| Scott, B | 1 |
| Yaksh, TL | 1 |
| YVANOFF, J | 1 |
| YVANOFF, F | 1 |
| Schmidt, R | 1 |
| Kunz, S | 1 |
| Gühring, H | 1 |
| Ritzeler, O | 1 |
| Michaelis, M | 1 |
| Rácz, I | 1 |
| Schütz, B | 1 |
| Abo-Salem, OM | 1 |
| Zimmer, A | 1 |
| Sánchez-Ramírez, GM | 1 |
| Caram-Salas, NL | 1 |
| Rocha-González, HI | 1 |
| Vidal-Cantú, GC | 1 |
| Medina-Santillán, R | 1 |
| Reyes-García, G | 1 |
| Akada, Y | 1 |
| Ogawa, S | 1 |
| Amano, K | 1 |
| Fukudome, Y | 1 |
| Yamasaki, F | 1 |
| Itoh, M | 1 |
| Yamamoto, I | 1 |
| Daud, A | 1 |
| Habib, N | 1 |
| Riera, AS | 1 |
| Hösl, K | 1 |
| Reinold, H | 1 |
| Harvey, RJ | 1 |
| Müller, U | 1 |
| Narumiya, S | 1 |
| Zeilhofer, HU | 1 |
| Torres-López, JE | 1 |
| Juárez-Rojop, IE | 1 |
| Diaz-Zagoya, JC | 1 |
| Flores-Murrieta, FJ | 1 |
| Ortíz-López, JU | 1 |
| Cruz-Vera, J | 1 |
| Chen, HS | 1 |
| He, X | 1 |
| Wen, WW | 1 |
| You, HJ | 1 |
| Arendt-Nielsen, L | 1 |
| Saito, O | 1 |
| Aoe, T | 1 |
| Bartolozzi, A | 1 |
| Sarva, J | 1 |
| Zhou, J | 1 |
| Kozikowski, A | 1 |
| Wroblewska, B | 1 |
| Kaku, R | 1 |
| Yokoyama, M | 1 |
| Kobayashi, H | 1 |
| Matsuoka, Y | 1 |
| Sato, T | 1 |
| Mizobuchi, S | 1 |
| Itano, Y | 1 |
| Morita, K | 1 |
| Dallel, R | 1 |
| Raboisson, P | 1 |
| Clavelou, P | 1 |
| Saade, M | 1 |
| Woda, A | 1 |
| Mansikka, H | 1 |
| Pertovaara, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis[NCT05603702] | Phase 1 | 24 participants (Anticipated) | Interventional | 2023-03-17 | Recruiting | ||
| Effect of Palmitoylethanolamide on Reducing Opioid Consumption for Postoperative Pain and Inflammation Following Below Knee Fracture Fixation: A Pilot Study.[NCT05317676] | Phase 2 | 0 participants (Actual) | Interventional | 2023-05-31 | Withdrawn (stopped due to Sponsor suspending temporarily.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
80 other studies available for formaldehyde and Neuralgia
| Article | Year |
|---|---|
Optimization of bifunctional piperidinamide derivatives as σ
Topics: Acetic Acid; Amides; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Formaldehyde; Guin | 2021 |
Spinal microglia contribute to sustained inflammatory pain via amplifying neuronal activity.
Topics: Animals; Formaldehyde; Mice; Microglia; Neuralgia; Neurons; Purinergic P2Y Receptor Antagonists | 2022 |
Store-operated calcium entry mediates hyperalgesic responses during neuropathy.
Topics: Analgesics; Calcium; Calcium Channels; Cells, Cultured; Formaldehyde; Humans; Neuralgia; Neurotransm | 2023 |
Effects of Chaerophyllum macropodum Boiss. leaves essential oil in inflammatory and neuropathic pain: uncovering the possible mechanism of action.
Topics: Analgesics; Analgesics, Opioid; Formaldehyde; Humans; Hyperalgesia; Neuralgia; Oils, Volatile; Plant | 2023 |
Spinal TASK-1 and TASK-3 modulate inflammatory and neuropathic pain.
Topics: Animals; Disease Models, Animal; Down-Regulation; Female; Formaldehyde; Ganglia, Spinal; Humans; Hyp | 2019 |
The phthalimide analogues N-3-hydroxypropylphthalimide and N-carboxymethyl-3-nitrophthalimide exhibit activity in experimental models of inflammatory and neuropathic pain.
Topics: Analgesics; Animals; Disease Models, Animal; Formaldehyde; Freund's Adjuvant; Hyperalgesia; Inflamma | 2019 |
Antinociceptive Effect of Spirocyclopiperazinium Salt Compound DXL-A-24 and the Underlying Mechanism.
Topics: Acetic Acid; Analgesics; Animals; Calcitonin Gene-Related Peptide; Calcium-Calmodulin-Dependent Prot | 2019 |
Formalin-induced and neuropathic pain altered time estimation in a temporal bisection task in rats.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Formaldehyde; Inflammation; Ligation; Male; Neura | 2019 |
Analgesic and antiallodynic activity of novel anticonvulsant agents derived from 3-benzhydryl-pyrrolidine-2,5-dione in mouse models of nociceptive and neuropathic pain.
Topics: Acute Pain; Analgesics; Animals; Anticonvulsants; Disease Models, Animal; Formaldehyde; Hep G2 Cells | 2020 |
Expressions of spinal microglia activation, BDNF, and DREAM proteins correlated with formalin-induced nociceptive responses in painful and painless diabetic neuropathy rats.
Topics: Animals; Brain-Derived Neurotrophic Factor; Diabetes Mellitus; Diabetic Neuropathies; Formaldehyde; | 2020 |
Attenuated dopamine receptor signaling in nucleus accumbens core in a rat model of chemically-induced neuropathy.
Topics: Animals; Conditioning, Operant; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dos | 2020 |
The intraperitoneal administration of MOTS-c produces antinociceptive and anti-inflammatory effects through the activation of AMPK pathway in the mouse formalin test.
Topics: AMP-Activated Protein Kinases; Analgesics; Animals; Anti-Inflammatory Agents; Cytokines; Enzyme Acti | 2020 |
Piperidine propionamide as a scaffold for potent sigma-1 receptor antagonists and mu opioid receptor agonists for treating neuropathic pain.
Topics: Amides; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Formaldehyde; Guinea Pigs | 2020 |
Lemairamin, isolated from the Zanthoxylum plants, alleviates pain hypersensitivity via spinal α7 nicotinic acetylcholine receptors.
Topics: Aconitine; Acrylamides; alpha7 Nicotinic Acetylcholine Receptor; Analgesics; Animals; beta-Endorphin | 2020 |
PCC0208009, an indirect IDO1 inhibitor, alleviates neuropathic pain and co-morbidities by regulating synaptic plasticity of ACC and amygdala.
Topics: Amygdala; Analgesics; Animals; Behavior, Animal; Comorbidity; Disease Models, Animal; Formaldehyde; | 2020 |
Oxytocin prevents neuronal network pain-related changes on spinal cord dorsal horn in vitro.
Topics: Animals; Animals, Newborn; Calcium; Female; Formaldehyde; Male; N-Methylaspartate; Nerve Net; Neural | 2020 |
Ifenprodil Reduced Expression of Activated Microglia, BDNF and DREAM Proteins in the Spinal Cord Following Formalin Injection During the Early Stage of Painful Diabetic Neuropathy in Rats.
Topics: Animals; Brain-Derived Neurotrophic Factor; Diabetic Neuropathies; Formaldehyde; Kv Channel-Interact | 2021 |
Calmodulin Supports TRPA1 Channel Association with Opioid Receptors and Glutamate NMDA Receptors in the Nervous Tissue.
Topics: Animals; Calmodulin; Constriction, Pathologic; Formaldehyde; Glutamic Acid; Inflammation; Male; Mice | 2020 |
Inhibition of Nav1.7 channel by a novel blocker QLS-81 for alleviation of neuropathic pain.
Topics: Action Potentials; Analgesics; Animals; Fluorobenzenes; Formaldehyde; Ganglia, Spinal; Guinea Pigs; | 2021 |
The spider toxin Phα1β recombinant possesses strong analgesic activity.
Topics: Analgesics, Non-Narcotic; Animals; Calcium Channel Blockers; Capsaicin; Formaldehyde; Male; Melanoma | 2017 |
Sinomenine produces peripheral analgesic effects via inhibition of voltage-gated sodium currents.
Topics: Animals; Antirheumatic Agents; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, | 2017 |
Antinociceptive, antiallodynic and antihyperalgesic effects of the 5-HT
Topics: Analgesics; Animals; Antineoplastic Agents; Cyclohexanes; Diabetic Neuropathies; Disease Models, Ani | 2017 |
3-Hydroxy-piperidinyl-N-benzyl-acyl-arylhydrazone derivatives reduce neuropathic pain and increase thermal threshold mediated by opioid system.
Topics: Analgesics, Opioid; Animals; Formaldehyde; Hydrazones; Male; Mice; Neuralgia; Pain Threshold; Rotaro | 2018 |
Treatment of chronic pain by designer cells controlled by spearmint aromatherapy.
Topics: Animals; Aromatherapy; Female; Formaldehyde; HEK293 Cells; Humans; Mentha spicata; Mice; Mice, Inbre | 2018 |
Antinociceptive curcuminoid, KMS4034, effects on inflammatory and neuropathic pain likely via modulating TRPV1 in mice.
Topics: Analgesics, Non-Narcotic; Animals; Calcitonin Gene-Related Peptide; Cells, Cultured; Curcumin; Drug | 2013 |
Different peripheral tissue injury induces differential phenotypic changes of spinal activated microglia.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Calcium-Binding Proteins; CD11b An | 2013 |
Distinct roles of neuregulin in different models of neuropathic pain.
Topics: Animals; Formaldehyde; Hyperalgesia; Male; Neuralgia; Neuregulin-1; Rats; Receptor, ErbB-2 | 2014 |
Analgesic effects of Huwentoxin-IV on animal models of inflammatory and neuropathic pain.
Topics: Acetic Acid; Analgesics; Animals; Behavior, Animal; Disease Models, Animal; Formaldehyde; Inflammati | 2014 |
Inferior alveolar nerve transection enhanced formalin-induced nocifensive responses in the upper lip: systemic buprenorphine had more antinociceptive efficacy over morphine.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Buprenorphine; Formaldehyde; Lip; Male; Mandibular Ne | 2014 |
Conjugation of a brain-penetrant peptide with neurotensin provides antinociceptive properties.
Topics: Analgesics; Animals; Blood-Brain Barrier; Bone Neoplasms; Capillary Permeability; Cell Line; Cell Li | 2014 |
Extracellular caspase-6 drives murine inflammatory pain via microglial TNF-α secretion.
Topics: Animals; Axons; Bradykinin; Caspase 6; Caspase Inhibitors; Cells, Cultured; Formaldehyde; Hyperalges | 2014 |
Intraganglionar resiniferatoxin prevents orofacial inflammatory and neuropathic hyperalgesia.
Topics: Animals; Capsaicin; Carrageenan; Cold Temperature; Disease Models, Animal; Diterpenes; Facial Pain; | 2014 |
Ovariectomy results in variable changes in nociception, mood and depression in adult female rats.
Topics: Affect; Animals; Behavior, Animal; Depression; Fear; Female; Formaldehyde; Hyperalgesia; Maze Learni | 2014 |
Citral: a monoterpene with prophylactic and therapeutic anti-nociceptive effects in experimental models of acute and chronic pain.
Topics: Acute Pain; Acyclic Monoterpenes; Analgesics; Animals; Capsaicin; Chronic Pain; Excitatory Amino Aci | 2014 |
Synthesis and analgesic effects of μ-TRTX-Hhn1b on models of inflammatory and neuropathic pain.
Topics: Acetic Acid; Analgesics; Animals; Disease Models, Animal; Formaldehyde; HEK293 Cells; Humans; Inflam | 2014 |
Upregulation of neuregulin-1 reverses signs of neuropathic pain in rats.
Topics: Analgesics; Animals; Behavior, Animal; Disease Models, Animal; Formaldehyde; Freund's Adjuvant; Gang | 2014 |
Chimeric agents derived from the functionalized amino acid, lacosamide, and the α-aminoamide, safinamide: evaluation of their inhibitory actions on voltage-gated sodium channels, and antiseizure and antinociception activities and comparison with lacosamid
Topics: Acetamides; Alanine; Analgesics; Animals; Anticonvulsants; Benzylamines; Cells, Cultured; Cerebral C | 2015 |
Antinociceptive activity of transient receptor potential channel TRPV1, TRPA1, and TRPM8 antagonists in neurogenic and neuropathic pain models in mice.
Topics: Acetanilides; Analgesics; Animals; Benzamides; Capsaicin; Cold Temperature; Disease Models, Animal; | 2015 |
The role of alpha5 nicotinic acetylcholine receptors in mouse models of chronic inflammatory and neuropathic pain.
Topics: Animals; Carrageenan; Formaldehyde; Freund's Adjuvant; Inflammation; Male; Mice; Mice, Inbred C57BL; | 2015 |
Inhibition of Spinal Interlukin-33/ST2 Signaling and Downstream ERK and JNK Pathways in Electroacupuncture Analgesia in Formalin Mice.
Topics: Animals; Electroacupuncture; Extracellular Signal-Regulated MAP Kinases; Formaldehyde; Interleukin-1 | 2015 |
Neuropathic Pain Phenotype Does Not Involve the NLRP3 Inflammasome and Its End Product Interleukin-1β in the Mice Spared Nerve Injury Model.
Topics: Animals; Behavior, Animal; Carrier Proteins; Disease Models, Animal; Female; Formaldehyde; Inflammas | 2015 |
The H2S-producing enzyme CSE is dispensable for the processing of inflammatory and neuropathic pain.
Topics: Animals; Cystathionine gamma-Lyase; Disease Models, Animal; Formaldehyde; Ganglia, Spinal; Gene Expr | 2015 |
EphrinB-EphB signaling regulates spinal pain processing via PKCγ.
Topics: Analysis of Variance; Animals; Bone Neoplasms; Disease Models, Animal; Ephrin-B2; Formaldehyde; Hype | 2015 |
Pharmacological modulation of neuropathic pain-related depression of behavior: effects of morphine, ketoprofen, bupropion and [INCREMENT]9-tetrahydrocannabinol on formalin-induced depression of intracranial self-stimulation in rats.
Topics: Analgesics; Analgesics, Opioid; Animals; Bupropion; Depression; Disease Models, Animal; Dose-Respons | 2016 |
Synthesis and Biological Evaluation of Novel σ1 Receptor Ligands for Treating Neuropathic Pain: 6-Hydroxypyridazinones.
Topics: Analgesics, Non-Narcotic; Animals; Chemistry Techniques, Synthetic; Disease Models, Animal; Dose-Res | 2016 |
Antinociceptive Profile of Levo-tetrahydropalmatine in Acute and Chronic Pain Mice Models: Role of spinal sigma-1 receptor.
Topics: Analgesics; Animals; Berberine Alkaloids; Chronic Pain; Ethylenediamines; Formaldehyde; Gene Express | 2016 |
Pulsed radiofrequency attenuates diabetic neuropathic pain and suppresses formalin-evoked spinal glutamate release in rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Formaldehyde; Glutamic Acid; Male; | 2016 |
Formalin injection produces long-lasting hypersensitivity with characteristics of neuropathic pain.
Topics: Activating Transcription Factor 3; Amines; Animals; Cyclohexanecarboxylic Acids; Female; Formaldehyd | 2017 |
Profound reduction of somatic and visceral pain in mice by intrathecal administration of the anti-migraine drug, sumatriptan.
Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Blood-Brain Barrier; Carrageenan; Drug Evaluation, P | 2008 |
KST5468, a new T-type calcium channel antagonist, has an antinociceptive effect on inflammatory and neuropathic pain models.
Topics: Analgesics; Animals; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Calcium Channels, T- | 2010 |
Inter-strain differences of serotonergic inhibitory pain control in inbred mice.
Topics: Animals; Chronic Disease; Disease Models, Animal; Formaldehyde; Ganglia, Spinal; Hyperalgesia; Infla | 2010 |
Reduction of formalin-evoked responses and maintenance of peripheral antinociception by morphine against formalin in the spared nerve injury model.
Topics: Analgesics, Opioid; Animals; Axotomy; Formaldehyde; Hindlimb; Irritants; Male; Morphine; Neuralgia; | 2011 |
Primary amino acid derivatives: compounds with anticonvulsant and neuropathic pain protection activities.
Topics: Amino Acids; Analgesics; Animals; Anticonvulsants; Convulsants; Electroshock; Formaldehyde; Male; Mi | 2011 |
Enhanced inhibitory synaptic transmission in the spinal dorsal horn mediates antinociceptive effects of TC-2559.
Topics: Analgesics; Animals; Biological Availability; Brain; Constriction, Pathologic; Dose-Response Relatio | 2011 |
The novel small molecule α9α10 nicotinic acetylcholine receptor antagonist ZZ-204G is analgesic.
Topics: Alkynes; Analgesics; Animals; Behavior, Animal; Benzene; Constriction, Pathologic; Feasibility Studi | 2011 |
Suppressive effects of glycyrrhetinic acid derivatives on tachykinin receptor activation and hyperalgesia.
Topics: Analgesics; Animals; Calcium; Capsaicin; CHO Cells; Cricetinae; Disease Models, Animal; Formaldehyde | 2011 |
Gelsenicine from Gelsemium elegans attenuates neuropathic and inflammatory pain in mice.
Topics: Acetic Acid; Alkaloids; Analgesics; Animals; Behavior, Animal; Drugs, Chinese Herbal; Formaldehyde; | 2011 |
The combined predictive capacity of rat models of algogen-induced and neuropathic hypersensitivity to clinically used analgesics varies with nociceptive endpoint and consideration of locomotor function.
Topics: Amines; Analgesics; Animals; Capsaicin; Cyclohexanecarboxylic Acids; Disease Models, Animal; Duloxet | 2012 |
Single cycle structure-based humanization of an anti-nerve growth factor therapeutic antibody.
Topics: Amino Acid Sequence; Analgesics; Animals; Antibodies, Monoclonal, Humanized; Antibody Specificity; C | 2012 |
Pharmacological properties of S1RA, a new sigma-1 receptor antagonist that inhibits neuropathic pain and activity-induced spinal sensitization.
Topics: Analgesics; Animals; Behavior, Animal; Capsaicin; Electric Stimulation; Formaldehyde; Gene Expressio | 2012 |
Inhibition of morphine tolerance is mediated by painful stimuli via central mechanisms.
Topics: Analgesics, Opioid; Animals; Corticosterone; Disease Models, Animal; Dose-Response Relationship, Dru | 2012 |
The p21-activated kinase PAK 5 is involved in formalin-induced nociception through regulation of MAP-kinase signaling and formalin-specific receptors.
Topics: Animals; Formaldehyde; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitoge | 2012 |
NAAG peptidase inhibition in the periaqueductal gray and rostral ventromedial medulla reduces flinching in the formalin model of inflammation.
Topics: Analgesics; Animals; Formaldehyde; Glutamate Carboxypeptidase II; Inflammation; Male; Medulla Oblong | 2012 |
Involvement of EphB1 receptors signalling in models of inflammatory and neuropathic pain.
Topics: Animals; Carrageenan; Cell Count; Disease Models, Animal; Electrophysiological Phenomena; Female; Fo | 2013 |
Palmitoylethanolamide reduces formalin-induced neuropathic-like behaviour through spinal glial/microglial phenotypical changes in mice.
Topics: Action Potentials; Amides; Animals; Endocannabinoids; Ethanolamines; Formaldehyde; Male; Mice; Mice, | 2013 |
Activation of p38 mitogen-activated protein kinase in spinal microglia is a critical link in inflammation-induced spinal pain processing.
Topics: Animals; Cyclooxygenase 2; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Formaldehyd | 2003 |
[New treatment for neuralgias].
Topics: Formaldehyde; Glucose; Humans; Neuralgia | 1956 |
[Clinical use of formol, with special reference to arthritic rheumatism].
Topics: Arthritis; Arthritis, Rheumatoid; Formaldehyde; Neuralgia; Rheumatic Diseases | 1958 |
Specific Inhibition of IkappaB kinase reduces hyperalgesia in inflammatory and neuropathic pain models in rats.
Topics: Active Transport, Cell Nucleus; Analgesics; Animals; Anti-Inflammatory Agents; Cells, Cultured; Cycl | 2004 |
Visceral, inflammatory and neuropathic pain in glycine receptor alpha 3-deficient mice.
Topics: Acetic Acid; Animals; Formaldehyde; Inflammation; Irritants; Mice; Mice, Mutant Strains; Neuralgia; | 2005 |
Benfotiamine relieves inflammatory and neuropathic pain in rats.
Topics: Adjuvants, Immunologic; Administration, Oral; Animals; Diabetes Mellitus, Experimental; Dose-Respons | 2006 |
Potent analgesic effects of a putative sodium channel blocker M58373 on formalin-induced and neuropathic pain in rats.
Topics: Analgesics; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Formaldehyde; Ganglia, Spina | 2006 |
Anti-inflammatory, anti-nociceptive and antipyretic effects of extracts of Phrygilanthus acutifolius flowers.
Topics: Acetic Acid; Administration, Oral; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non- | 2006 |
Spinal prostaglandin E receptors of the EP2 subtype and the glycine receptor alpha3 subunit, which mediate central inflammatory hyperalgesia, do not contribute to pain after peripheral nerve injury or formalin injection.
Topics: Animals; Formaldehyde; Hyperalgesia; Inflammation; Injections; Mice; Mice, Knockout; Neuralgia; Pain | 2006 |
Peripheral participation of cholecystokinin in the morphine-induced peripheral antinociceptive effect in non-diabetic and diabetic rats.
Topics: Animals; Area Under Curve; Cholecystokinin; Diabetes Mellitus, Experimental; Dose-Response Relations | 2007 |
Roles of capsaicin-sensitive primary afferents in differential rat models of inflammatory pain: a systematic comparative study in conscious rats.
Topics: Analgesics, Non-Narcotic; Animals; Bee Venoms; Behavior, Animal; Capsaicin; Carrageenan; Edema; Form | 2007 |
Local administration of N-acetylaspartylglutamate (NAAG) peptidase inhibitors is analgesic in peripheral pain in rats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carrageenan; Cells, Cultured; Cerebellum; Cricetinae; Cricetul | 2007 |
Altered response to formalin by L5 spinal nerve ligation in rats: a behavioral and molecular study.
Topics: Acute Disease; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Calcitonin Gene-Related | 2007 |
Evidence for a peripheral origin of the tonic nociceptive response to subcutaneous formalin.
Topics: Afferent Pathways; Analysis of Variance; Animals; Formaldehyde; Injections, Subcutaneous; Lip; Male; | 1995 |
Submodality-selective hyperalgesia adjacent to partially injured sciatic nerve in the rat is dependent on capsaicin-sensitive afferent fibers and independent of collateral sprouting or a dorsal root reflex.
Topics: Animals; Capsaicin; Extravasation of Diagnostic and Therapeutic Materials; Formaldehyde; Ganglia, Sp | 1997 |