Page last updated: 2024-10-18

formaldehyde and Nasopharyngeal Carcinoma

formaldehyde has been researched along with Nasopharyngeal Carcinoma in 2 studies

paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy

Nasopharyngeal Carcinoma: A carcinoma that originates in the EPITHELIUM of the NASOPHARYNX and includes four subtypes: keratinizing squamous cell, non-keratinizing, basaloid squamous cell, and PAPILLARY ADENOCARCINOMA. It is most prevalent in Southeast Asian populations and is associated with EPSTEIN-BARR VIRUS INFECTIONS. Somatic mutations associated with this cancer have been identified in NPCR, BAP1, UBAP1, ERBB2, ERBB3, MLL2, PIK3CA, KRAS, NRAS, and ARID1A genes.

Research Excerpts

ExcerptRelevanceReference
" Finally, we compare a new bottom-up slope estimate of the risk of rat nasal cancer with conventional top-down estimates obtained with empirical dose-response modeling of rat nasal cancer bioassay data."1.43The bottom-up approach to bounding potential low-dose cancer risks from formaldehyde: An update. ( Starr, TB; Swenberg, JA, 2016)
"Formaldehyde is a well-studied chemical and effects from inhalation exposures have been extensively characterized in numerous controlled studies with human volunteers, including asthmatics and other sensitive individuals, which provide a rich database on exposure concentrations that can reliably produce the symptoms of sensory irritation."1.37Identifying an indoor air exposure limit for formaldehyde considering both irritation and cancer hazards. ( Golden, R, 2011)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Starr, TB1
Swenberg, JA1
Golden, R1

Other Studies

2 other studies available for formaldehyde and Nasopharyngeal Carcinoma

ArticleYear
The bottom-up approach to bounding potential low-dose cancer risks from formaldehyde: An update.
    Regulatory toxicology and pharmacology : RTP, 2016, Volume: 77

    Topics: Animals; Carcinogenicity Tests; Carcinoma; DNA Adducts; Dose-Response Relationship, Drug; Fixatives;

2016
Identifying an indoor air exposure limit for formaldehyde considering both irritation and cancer hazards.
    Critical reviews in toxicology, 2011, Volume: 41, Issue:8

    Topics: Air Pollution, Indoor; Carcinoma; Formaldehyde; Humans; Inhalation Exposure; Irritants; Leukemia; Na

2011