Page last updated: 2024-10-18

formaldehyde and Multiple Myeloma

formaldehyde has been researched along with Multiple Myeloma in 7 studies

paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy

Multiple Myeloma: A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.

Research Excerpts

ExcerptRelevanceReference
"52 specimens from 34 patients with multiple myeloma and 3 cases with reactive plasmacytosis were stained by the 2-step labelled or 3-step unlabelled immunoperoxidase (IP) technique for demonstration of intracellular immunoglobulin in order to test the utility of these methods as staining methods in routine diagnostic work."1.26Immunohistochemical demonstration of intracellular immunoglobulin in formalin fixed, paraffin embedded sections, as staining method in diagnostic work. ( Clausen, PP; Jacobsen, M; Johansen, P; Thommesen, N, 1979)
"Study of material from 500 cases of Hodgkin's disease, non-Hodgkin lymphomas, and myeloma has revealed that many of these conditions may find a common origin in the lymphocyte, and that some malignant cells, previously identified as malignant histiocytes or reticulum cells are rather related to or derived from the transformed lymphocyte or immunoblast."1.26Immunocytochemical methods in the study of lymphoma and related conditions. ( Taylor, CR, 1978)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gebauer, N1
Bernard, V1
Röhner, C1
Krokowski, M1
Merz, H1
Feller, AC1
Thorns, C1
Neat, MJ1
Moonim, MT1
Dunn, RG1
Geoghegan, H1
Foot, NJ1
Shinagawa, A1
Kojima, H1
Berndt, MC1
Kaneko, S1
Suzukawa, K1
Hasegawa, Y1
Shigeta, O1
Nagasawa, T1
Lehmann, U1
Bock, O1
Länger, F1
Kreipe, H1
Clausen, PP1
Jacobsen, M1
Johansen, P1
Thommesen, N1
Taylor, CR2

Other Studies

7 other studies available for formaldehyde and Multiple Myeloma

ArticleYear
Pyrosequencing as a fast and reliable method in detecting the MYD88 p.L265P mutation in decalcified formalin-fixed and paraffin-embedded tissues.
    Annals of laboratory medicine, 2014, Volume: 34, Issue:2

    Topics: Adult; Aged; Base Sequence; Bone Marrow; Female; Formaldehyde; Gene Frequency; Humans; Male; Middle

2014
Fluorescence in situ hybridisation analysis of bone marrow trephine biopsy specimens; an additional tool in the diagnostic armoury.
    Journal of clinical pathology, 2013, Volume: 66, Issue:1

    Topics: Acute Disease; Aged; Biopsy; Bone Marrow; Bone Marrow Diseases; Bone Marrow Examination; Chromosome

2013
Characterization of a myeloma patient with a life-threatening hemorrhagic diathesis: presence of a lambda dimer protein inhibiting shear-induced platelet aggregation by binding to the A1 domain of von Willebrand factor.
    Thrombosis and haemostasis, 2005, Volume: 93, Issue:5

    Topics: Adenosine Diphosphate; Adrenergic Agonists; Antibodies, Monoclonal; Anticoagulants; Blood Coagulatio

2005
Demonstration of light chain restricted clonal B-lymphoid infiltrates in archival bone marrow trephines by quantitative real-time polymerase chain reaction.
    The American journal of pathology, 2001, Volume: 159, Issue:6

    Topics: B-Lymphocytes; Biopsy; Bone Marrow; Clone Cells; DNA, Complementary; Fixatives; Formaldehyde; HL-60

2001
Immunohistochemical demonstration of intracellular immunoglobulin in formalin fixed, paraffin embedded sections, as staining method in diagnostic work.
    Acta pathologica et microbiologica Scandinavica. Section C, Immunology, 1979, Volume: 87C, Issue:4

    Topics: Bone Neoplasms; Formaldehyde; Histological Techniques; Humans; Immune Sera; Immunoenzyme Techniques;

1979
Immunocytochemical methods in the study of lymphoma and related conditions.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1978, Volume: 26, Issue:7

    Topics: Formaldehyde; Hodgkin Disease; Humans; Immunoenzyme Techniques; Immunoglobulin A; Immunoglobulin G;

1978
The nature of Reed-Sternberg cells and other malignant "reticulum" cells.
    Lancet (London, England), 1974, Oct-05, Volume: 2, Issue:7884

    Topics: Animals; Formaldehyde; Histiocytes; Hodgkin Disease; Humans; Immune Sera; Immunoglobulins; Immunolog

1974