Page last updated: 2024-10-18

formaldehyde and Metaplasia

formaldehyde has been researched along with Metaplasia in 13 studies

paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy

Metaplasia: A condition in which there is a change of one adult cell type to another similar adult cell type.

Research Excerpts

ExcerptRelevanceReference
" Inhaled formaldehyde gas induces squamous metaplasia posterior to the nasal vestibule and does not induce lesions in the nasal vestibule in rats and rhesus monkeys, indicating that squamous epithelium is resistant to irritant effects of formaldehyde and that squamous metaplasia may be an adaptive response."7.69Correlation of regional formaldehyde flux predictions with the distribution of formaldehyde-induced squamous metaplasia in F344 rat nasal passages. ( Conolly, RB; Gross, EA; Kimbell, JS; Morgan, KT; Richardson, RB, 1997)
"Chronic exposures to high concentrations (> or = 6 ppm) of formaldehyde (HCHO) induce cell proliferation, squamous metaplasia, and squamous cell carcinomas in F344 rats."3.69DNA-protein cross-links and cell replication at specific sites in the nose of F344 rats exposed subchronically to formaldehyde. ( Casanova, M; Gross, EA; Heck, HA; Morgan, KT; Moss, OR, 1994)
" Inhaled formaldehyde gas induces squamous metaplasia posterior to the nasal vestibule and does not induce lesions in the nasal vestibule in rats and rhesus monkeys, indicating that squamous epithelium is resistant to irritant effects of formaldehyde and that squamous metaplasia may be an adaptive response."3.69Correlation of regional formaldehyde flux predictions with the distribution of formaldehyde-induced squamous metaplasia in F344 rat nasal passages. ( Conolly, RB; Gross, EA; Kimbell, JS; Morgan, KT; Richardson, RB, 1997)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's3 (23.08)18.2507
2000's3 (23.08)29.6817
2010's0 (0.00)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Nishikawa, A1
Nagano, K1
Kojima, H1
Ogawa, K1
Jhala, NC1
Montemor, M1
Jhala, D1
Lu, L1
Talley, L1
Haber, MM1
Lechago, J1
Cassee, FR1
de Burbure, CY1
Rambali, B1
Vleeming, W1
van de Kuil, A1
van Steeg, H1
Fokkens, PH1
van Amsterdam, JG1
Dormans, JA1
Opperhuizen, A1
Andersen, ME1
Clewell, HJ1
Bermudez, E1
Willson, GA1
Thomas, RS1
Klein-Szanto, AJ1
Nettesheim, P1
Pine, A1
Martin, D1
Casanova, M1
Morgan, KT2
Gross, EA2
Moss, OR2
Heck, HA1
Ohtsuka, R1
Shuto, Y1
Fujie, H1
Takeda, M1
Harada, T1
Itagaki, S1
Kimbell, JS1
Richardson, RB1
Conolly, RB1
Watt, J1
Gregory, I1
Stell, PM1
Woutersen, RA1
van Garderen-Hoetmer, A1
Bruijntjes, JP1
Zwart, A1
Feron, VJ1
Berke, JH1
Edling, C1
Hellquist, H1
Odkvist, L1
Maronpot, RR1
Miller, RA1
Clarke, WJ1
Westerberg, RB1
Decker, JR1

Reviews

1 review available for formaldehyde and Metaplasia

ArticleYear
A comprehensive review of mechanistic insights into formaldehyde-induced nasal cavity carcinogenicity.
    Regulatory toxicology and pharmacology : RTP, 2021, Volume: 123

    Topics: Administration, Inhalation; Animals; Carcinogens; Cell Proliferation; Formaldehyde; Hyperplasia; Met

2021

Other Studies

12 other studies available for formaldehyde and Metaplasia

ArticleYear
Pancreatic acinar cell metaplasia in autoimmune gastritis.
    Archives of pathology & laboratory medicine, 2003, Volume: 127, Issue:7

    Topics: Autoimmune Diseases; Carrier Proteins; Formaldehyde; Gastrectomy; Gastric Mucosa; Gastrins; Gastriti

2003
Subchronic inhalation of mixtures of cigarette smoke constituents in Xpa-/-p53+/- knock-out mice: a comparison of intermittent with semi-continuous exposure to acetaldehyde, formaldehyde, and acrolein.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2008, Volume: 46, Issue:2

    Topics: Acetaldehyde; Acrolein; Administration, Inhalation; Animals; Atmosphere Exposure Chambers; Disinfect

2008
Genomic signatures and dose-dependent transitions in nasal epithelial responses to inhaled formaldehyde in the rat.
    Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 105, Issue:2

    Topics: Animals; Cell Membrane; Cell Proliferation; Cluster Analysis; Dose-Response Relationship, Drug; Extr

2008
Distribution and ultrastructural characteristics of dark cells in squamous metaplasias of the respiratory tract epithelium.
    The American journal of pathology, 1981, Volume: 103, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Epithelium; Female; Formaldehyde; Metaplasia; Pregnancy;

1981
DNA-protein cross-links and cell replication at specific sites in the nose of F344 rats exposed subchronically to formaldehyde.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1994, Volume: 23, Issue:4

    Topics: Administration, Inhalation; Animals; Cell Division; DNA; Formaldehyde; Male; Metaplasia; Nasal Mucos

1994
Response of respiratory epithelium of BN and F344 rats to formaldehyde inhalation.
    Experimental animals, 1997, Volume: 46, Issue:4

    Topics: Administration, Inhalation; Aerosols; Animals; Epithelial Cells; Formaldehyde; Lung; Male; Metaplasi

1997
Correlation of regional formaldehyde flux predictions with the distribution of formaldehyde-induced squamous metaplasia in F344 rat nasal passages.
    Mutation research, 1997, Oct-31, Volume: 380, Issue:1-2

    Topics: Administration, Inhalation; Animals; Computer Simulation; Disease Progression; Formaldehyde; Metapla

1997
Alcian blue method for the museum display of squamous metaplasia in the larynx.
    The Journal of pathology, 1975, Volume: 117, Issue:2

    Topics: Adult; Alcian Blue; Education, Medical; Epithelial Cells; Epithelium; Exhibitions as Topic; Formalde

1975
Nasal tumours in rats after severe injury to the nasal mucosa and prolonged exposure to 10 ppm formaldehyde.
    Journal of applied toxicology : JAT, 1989, Volume: 9, Issue:1

    Topics: Animals; Body Weight; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Electrocoagulation

1989
Cytologic examination of the nasal mucosa in formaldehyde-exposed workers.
    Journal of occupational medicine. : official publication of the Industrial Medical Association, 1987, Volume: 29, Issue:8

    Topics: Adult; Age Factors; Aged; Cross-Sectional Studies; Formaldehyde; Humans; Metaplasia; Middle Aged; Na

1987
Occupational formaldehyde exposure and the nasal mucosa.
    Rhinology, 1987, Volume: 25, Issue:3

    Topics: Adult; Aged; Formaldehyde; Humans; Metaplasia; Middle Aged; Nasal Mucosa; Nose Diseases; Nose Neopla

1987
Toxicity of formaldehyde vapor in B6C3F1 mice exposed for 13 weeks.
    Toxicology, 1986, Volume: 41, Issue:3

    Topics: Animals; Body Weight; Female; Formaldehyde; Larynx; Male; Metaplasia; Mice; Mice, Inbred Strains; No

1986