formaldehyde has been researched along with Lung Neoplasms in 202 studies
paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A possible relationship between exposure to formaldehyde and leukemia-particularly myeloid leukemia-as well as of lymphoid neoplasms has been debated and is still controversial." | 3.80 | Mortality from lymphohematopoietic neoplasms and other causes in a cohort of laminated plastic workers exposed to formaldehyde. ( La Vecchia, C; Pira, E; Romano, C; Verga, F, 2014) |
| "Family-based analyses showed that a quercetin-rich diet differentiated miR expression profiles of the tumor suppressor let-7 family among adenocarcinomas (P(FCS) < 0." | 3.78 | Influence of quercetin-rich food intake on microRNA expression in lung cancer tissues. ( Bertazzi, PA; Caporaso, NE; Lam, TK; Landi, MT; Marincola, F; Pesatori, A; Shao, S; Wang, E; Zhao, Y, 2012) |
| "A number of bladder cancer case-control studies have noted an association with work as a machinist." | 2.40 | Oils and cancer. ( Tolbert, PE, 1997) |
| "Sulfuric acid appears to cause laryngeal cancer." | 2.40 | Reactive chemicals and cancer. ( Blair, A; Kazerouni, N, 1997) |
| "Pioglitazone treatment significantly reduced squamous lesions and the presence of airway basal cells, along with increasing normal epithelial cells in the airways of NTCU-exposed mice." | 1.72 | PPARgamma agonism inhibits progression of premalignant lesions in a murine lung squamous cell carcinoma model. ( Alavi, K; Dwyer-Nield, LD; Ghosh, M; Hudish, LI; Hudish, TM; Keith, RL; McArthur, DG; Merrick, DT; Mirita, C; Smith, AJ; Sompel, K; Tennis, MA, 2022) |
| "Despite progress in treatment of small cell lung cancer (SCLC), its multidrug chemoresistance and poor prognosis still remain." | 1.48 | Long non-coding RNA HOTTIP promotes BCL-2 expression and induces chemoresistance in small cell lung cancer by sponging miR-216a. ( Guo, L; Guo, Y; Hu, B; Qiu, Q; Sun, Y; Wang, Q; Ye, M; Zeng, F; Zhang, X; Zhou, Y, 2018) |
| "Lung cancer is a prototypic example and one of the leading causes of cancer-related deaths worldwide." | 1.46 | Optimized expression-based microdissection of formalin-fixed lung cancer tissue. ( Beck, J; Bohnenberger, H; Büttner, R; Danner, BC; Emmert, A; Grafen, M; Hofmann, TR; Küffer, S; Ostendorf, A; Scheel, AH; Schütz, E; Ströbel, P, 2017) |
| "Case 2: A 64-year-old man with stage IV colon cancer (multiple para-aortic lymph node metastases and direct abdominal wall invasion) underwent non-curative surgery in May 2006." | 1.46 | Long-lasting complete response status of advanced stage IV gall bladder cancer and colon cancer after combined treatment including autologous formalin-fixed tumor vaccine: two case reports. ( Imaoka, Y; Kuranishi, F; Miyazaki, T; Ohno, T; Yasuda, H, 2017) |
| "Lung cancer is the most common cause of cancer-related deaths worldwide, and metastatic spread of the cancer rather than the primary tumor is the main cause of death." | 1.39 | Identification of accurate reference genes for RT-qPCR analysis of formalin-fixed paraffin-embedded tissue from primary non-small cell lung cancers and brain and lymph node metastases. ( Alsner, J; Hager, H; Hansen, LL; Kristensen, LS; Overgaard, J; Søes, S; Sørensen, BS, 2013) |
| "In the first study on breast cancer samples, we assessed whether a human epidermal growth factor receptor (HER) 2 score based on immunohistochemistry (IHC) could be reproduced with RPPA." | 1.39 | Multiple protein analysis of formalin-fixed and paraffin-embedded tissue samples with reverse phase protein arrays. ( Arbogast, S; Assadi, M; Breitinger, E; Essioux, L; Farfsing, A; Gierke, B; Jarutat, T; Lamerz, J; Langen, H; Paul, H; Pawlak, M; Schindler, T; Templin, MF; Venturi, M, 2013) |
| "Carcinoid tumors are a heterogeneous group of neoplasms arising from the diffuse neuroendocrine system." | 1.32 | Analysis of chromosome-11 aberrations in pulmonary and gastrointestinal carcinoids: an array comparative genomic hybridization-based study. ( Halbwedl, I; Petzmann, S; Popper, HH; Ullmann, R, 2004) |
| "The time-dependent dose-response relationships for the induction of DNA double-strand breaks (DSB) assessed by pulsed-field gel electrophoresis (PFGE) and for viability (evaluated by the MTT cytotoxicity test) were investigated in order to discriminate between genotoxic and cytotoxic mechanisms of DNA fragmentation." | 1.30 | Discrimination between genotoxicity and cytotoxicity for the induction of DNA double-strand breaks in cells treated with aldehydes and diepoxides. ( Ilinskaya, O; Lutz, WK; Vamvakas, S; Vock, EH, 1999) |
| "Only one case of nasopharyngeal cancer had any appreciable exposure to formaldehyde." | 1.29 | Mortality among chemical workers in a factory where formaldehyde was used. ( Esmen, NA; Henderson, VL; Lee, KY; Marsh, GM; Stone, RA, 1996) |
| "There was no excess of deaths for cancers of all sites but slight increases in deaths from cancer of the lung (SMR = 131, CI 95% = 88-182), bladder (SMR = 150, CI 95% = 48-349), kidney (SMR = 323, CI 95% = 86-827), pancreas (SMR = 146, CI 95% = 39-373), and leukaemias (SMR = 164, CI 95% = 53-382) occurred." | 1.28 | Cancer mortality among workers in the Tuscan tanning industry. ( Buiatti, E; Costantini, AS; Lenzi, S; Martelli, C; Miligi, L; Paci, E, 1989) |
| "No deaths from nasal cancer were reported (1." | 1.27 | Formaldehyde in the British chemical industry. An occupational cohort study. ( Acheson, ED; Barnes, HR; Gardner, MJ; Osmond, C; Pannett, B; Taylor, CP, 1984) |
| "Cold acetone was found to be superior to formalin for the preservation of CEA and keratin antigenic activities in a variety of benign and malignant tissues." | 1.27 | Comparison of formalin- and acetone-fixation for immunohistochemical detection of carcinoembryonic antigen (CEA) and keratin. ( Bailey, DJ; Ekem, JK; Farber, E; Kaku, T; Lindayen, C; Van Nostrand, AW, 1983) |
| "Recent animal studies found nasal cancer among rats exposed to formaldehyde, but no excess of this tumor occurred in this study." | 1.27 | Mortality among industrial workers exposed to formaldehyde. ( Bales, R; Blair, A; Cubit, D; Gaffey, W; Kaplan, S; O'Berg, M; Stewart, P; Walrath, J; Ward, J, 1986) |
| "Mortality from digestive cancer (14 deaths observed) and hematologic neoplasms (5 deaths observed) was not substantially higher than expected." | 1.27 | Exposure to formaldehyde and cancer mortality in a cohort of workers producing resins. ( Bertazzi, PA; Pesatori, AC; Radice, L; Vai, T; Zocchetti, C, 1986) |
| "No deaths from nasal cancer have been reported in epidemiologic studies of cohorts exposed to formaldehyde, but three case-control studies suggest the possibility of increased risk." | 1.27 | Contribution of formaldehyde to respiratory cancer. ( Albert, RE; Blair, AE; Griesemer, RA; Landrigan, PJ; Levine, RJ; Nelson, N; Stayner, LT; Swenberg, JA, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (15.35) | 18.7374 |
| 1990's | 39 (19.31) | 18.2507 |
| 2000's | 18 (8.91) | 29.6817 |
| 2010's | 79 (39.11) | 24.3611 |
| 2020's | 35 (17.33) | 2.80 |
| Authors | Studies |
|---|---|
| Burns, JA | 1 |
| Li, Y | 7 |
| Cheney, CA | 1 |
| Ou, Y | 1 |
| Franlin-Pfeifer, LL | 1 |
| Kuklin, N | 1 |
| Zhang, ZQ | 1 |
| Martínez, A | 1 |
| Miller, MJ | 1 |
| Quinn, K | 1 |
| Unsworth, EJ | 1 |
| Ebina, M | 1 |
| Cuttitta, F | 1 |
| Chen, YL | 1 |
| Chen, WL | 1 |
| Cheng, YC | 1 |
| Lin, MC | 1 |
| Yang, SC | 1 |
| Tsai, HW | 1 |
| Lin, CC | 1 |
| Su, WC | 1 |
| Chow, NH | 1 |
| Ho, CL | 1 |
| Cazzato, G | 1 |
| Caporusso, C | 1 |
| Arezzo, F | 1 |
| Cimmino, A | 1 |
| Colagrande, A | 1 |
| Loizzi, V | 1 |
| Cormio, G | 1 |
| Lettini, T | 1 |
| Maiorano, E | 1 |
| Scarcella, VS | 1 |
| Tarantino, P | 1 |
| Marrone, M | 1 |
| Stellacci, A | 1 |
| Parente, P | 1 |
| Romita, P | 1 |
| De Marco, A | 1 |
| Venerito, V | 1 |
| Foti, C | 1 |
| Ingravallo, G | 1 |
| Rossi, R | 1 |
| Resta, L | 1 |
| Peñaloza Coronas, C | 1 |
| Montilla Fonseca, SM | 1 |
| Sánchez, ML | 1 |
| Yao, ZG | 1 |
| Wei, ZG | 1 |
| Cheng, XK | 1 |
| Huang, GH | 1 |
| Zong, YY | 1 |
| Meng, M | 1 |
| Li, JM | 1 |
| Han, XY | 1 |
| Xu, JW | 1 |
| Wang, J | 1 |
| Jing, HY | 1 |
| Li, WH | 1 |
| Cao, ZX | 1 |
| Ni, Y | 1 |
| Sun, XC | 1 |
| Yang, X | 1 |
| Ye, X | 1 |
| Hwang, CC | 1 |
| Hsieh, TY | 1 |
| Yeh, KY | 1 |
| Chen, TP | 1 |
| Hua, CC | 1 |
| Chang, LC | 1 |
| Chen, JR | 1 |
| Werner, TV | 1 |
| Kock, S | 1 |
| Weber, I | 1 |
| Kayser, G | 1 |
| Werner, M | 1 |
| Lassmann, S | 1 |
| Dwyer-Nield, LD | 1 |
| McArthur, DG | 1 |
| Hudish, TM | 1 |
| Hudish, LI | 1 |
| Mirita, C | 1 |
| Sompel, K | 1 |
| Smith, AJ | 1 |
| Alavi, K | 1 |
| Ghosh, M | 1 |
| Merrick, DT | 1 |
| Tennis, MA | 1 |
| Keith, RL | 1 |
| Penault-Llorca, F | 1 |
| Kerr, KM | 1 |
| Garrido, P | 1 |
| Thunnissen, E | 1 |
| Dequeker, E | 1 |
| Normanno, N | 1 |
| Patton, SJ | 1 |
| Fairley, J | 1 |
| Kapp, J | 1 |
| de Ridder, D | 1 |
| Ryška, A | 1 |
| Moch, H | 2 |
| Atari, M | 1 |
| Imai, K | 1 |
| Nanjo, H | 1 |
| Wakamatsu, Y | 1 |
| Takashima, S | 1 |
| Kurihara, N | 1 |
| Kuriyama, S | 1 |
| Suzuki, H | 1 |
| Demura, R | 1 |
| Harata, Y | 1 |
| Hiroshima, Y | 1 |
| Sato, Y | 1 |
| Nomura, K | 1 |
| Minamiya, Y | 1 |
| Amemiya, K | 1 |
| Hirotsu, Y | 1 |
| Mochizuki, H | 1 |
| Higuchi, R | 1 |
| Nakagomi, T | 1 |
| Goto, T | 1 |
| Oyama, T | 1 |
| Kondo, T | 1 |
| Omata, M | 1 |
| Kim, S | 1 |
| Koh, J | 1 |
| Song, SG | 1 |
| Yim, J | 1 |
| Kim, M | 1 |
| Keam, B | 1 |
| Kim, YT | 1 |
| Kim, J | 1 |
| Chung, DH | 2 |
| Jeon, YK | 1 |
| Jiang, J | 4 |
| Tang, C | 3 |
| Lin, Z | 3 |
| Li, Z | 3 |
| Zhou, C | 3 |
| Gu, Y | 4 |
| He, P | 3 |
| Tang, Q | 3 |
| Zhang, Y | 3 |
| Deng, Q | 3 |
| Ge, Y | 3 |
| Liang, W | 3 |
| He, J | 3 |
| Ozyoruk, KB | 1 |
| Can, S | 1 |
| Darbaz, B | 1 |
| Başak, K | 1 |
| Demir, D | 1 |
| Gokceler, GI | 1 |
| Serin, G | 1 |
| Hacisalihoglu, UP | 1 |
| Kurtuluş, E | 1 |
| Lu, MY | 1 |
| Chen, TY | 1 |
| Williamson, DFK | 1 |
| Yılmaz, F | 1 |
| Mahmood, F | 1 |
| Turan, M | 1 |
| Wang, N | 1 |
| Zhang, L | 2 |
| Ying, Q | 1 |
| Song, Z | 1 |
| Lu, A | 1 |
| Treumann, A | 1 |
| Liu, Z | 1 |
| Sun, T | 1 |
| Ding, Z | 1 |
| Guo, Y | 2 |
| Hou, Y | 1 |
| Lv, C | 1 |
| Ma, X | 1 |
| Yang, M | 1 |
| Jin, Y | 1 |
| Li, B | 1 |
| Liu, W | 1 |
| Ackermann, BL | 1 |
| Morrison, RD | 1 |
| Hill, S | 1 |
| Westfall, MD | 1 |
| Butts, BD | 1 |
| Soper, MD | 1 |
| Fill, JA | 1 |
| Schade, AE | 1 |
| Liebler, DC | 1 |
| Gruver, AM | 1 |
| Ismail, MS | 1 |
| Kassem, L | 1 |
| Ali, AA | 1 |
| Ahmed, FE | 1 |
| Shalaby, M | 1 |
| Magdy, S | 1 |
| Ju, S | 1 |
| Cui, Z | 1 |
| Hong, Y | 1 |
| Wang, X | 2 |
| Mu, W | 1 |
| Xie, Z | 1 |
| Zeng, X | 1 |
| Su, L | 1 |
| Lin, X | 1 |
| Zhang, Z | 2 |
| Zhang, Q | 2 |
| Song, X | 1 |
| You, S | 1 |
| Chen, R | 1 |
| Chen, W | 1 |
| Xu, C | 1 |
| Zhao, J | 1 |
| Wang, LC | 1 |
| Hsieh, YH | 1 |
| Hung, YL | 1 |
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| Lin, YC | 1 |
| Chang, MD | 1 |
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| Citak, S | 1 |
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| Bayram, S | 1 |
| Vayvada, M | 1 |
| Metin, SK | 1 |
| Baysungur, V | 1 |
| Buonocore, DJ | 1 |
| Konno, F | 1 |
| Jungbluth, AA | 2 |
| Frosina, D | 1 |
| Fayad, M | 1 |
| Edelweiss, M | 1 |
| Lin, O | 1 |
| Rekhtman, N | 1 |
| Evrard, SM | 1 |
| Taranchon-Clermont, E | 1 |
| Rouquette, I | 1 |
| Murray, S | 1 |
| Dintner, S | 1 |
| Nam-Apostolopoulos, YC | 1 |
| Bellosillo, B | 1 |
| Varela-Rodriguez, M | 1 |
| Nadal, E | 2 |
| Wiedorn, KH | 1 |
| Melchior, L | 1 |
| Andrew, E | 1 |
| Jones, M | 1 |
| Ridgway, J | 1 |
| Frykman, C | 1 |
| Lind, L | 1 |
| Rot, M | 1 |
| Kern, I | 1 |
| Speel, EJM | 1 |
| Roemen, GMJM | 1 |
| Trincheri, N | 1 |
| Freiberger, SN | 1 |
| Rechsteiner, M | 1 |
| Heeke, S | 1 |
| Hofman, P | 1 |
| Southwood, M | 1 |
| Krenz, T | 1 |
| Cant, N | 1 |
| Maurya, M | 1 |
| Gazdova, J | 1 |
| Maxwell, P | 1 |
| McGready, C | 1 |
| Moseley, E | 1 |
| Hughes, S | 1 |
| Stewart, P | 2 |
| Salto-Tellez, M | 1 |
| Groelz, D | 1 |
| Rassl, D | 1 |
| Rashid, R | 1 |
| Gaglia, G | 1 |
| Chen, YA | 1 |
| Lin, JR | 1 |
| Du, Z | 1 |
| Maliga, Z | 1 |
| Schapiro, D | 1 |
| Yapp, C | 1 |
| Muhlich, J | 1 |
| Sokolov, A | 1 |
| Sorger, P | 1 |
| Santagata, S | 1 |
| Kwak, K | 1 |
| Paek, D | 1 |
| Park, JT | 1 |
| Delgado-García, M | 1 |
| Weynand, B | 1 |
| Gómez-Izquierdo, L | 1 |
| Hernández, MJ | 1 |
| Blanco, ÁM | 1 |
| Varela, M | 1 |
| Matias-Guiu, X | 1 |
| Márquez-Lobo, B | 1 |
| Alarcão, A | 1 |
| de Álava, E | 1 |
| Biscuola, M | 1 |
| Zhang, S | 1 |
| Li, X | 2 |
| Zhao, Z | 1 |
| Chen, C | 1 |
| Zhang, J | 1 |
| Li, M | 1 |
| Wei, Z | 1 |
| Jiang, W | 1 |
| Pan, B | 1 |
| Liu, Y | 1 |
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| de Schaetzen van Brienen, L | 1 |
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| Ost, P | 1 |
| Marchal, K | 1 |
| Koomen, BM | 1 |
| van der Starre-Gaal, J | 1 |
| Vonk, JM | 1 |
| von der Thüsen, JH | 1 |
| van der Meij, JJC | 1 |
| Monkhorst, K | 1 |
| Willems, SM | 1 |
| Timens, W | 1 |
| 't Hart, NA | 1 |
| Javey, M | 1 |
| Reinsch, C | 1 |
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| Hinzmann, B | 1 |
| Heilek, G | 1 |
| Palma, JF | 1 |
| Cabán-Rivera, J | 1 |
| Chardón-Colón, C | 1 |
| Pedraza-Torres, A | 1 |
| Rodríguez, YE | 1 |
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| Santiago-Cardona, PG | 2 |
| Yan, YH | 1 |
| Chen, SX | 1 |
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| Zhang, DY | 1 |
| Carvalho, TM | 1 |
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| Barros Duarte, CA | 1 |
| Ioshii, SO | 1 |
| Riediger, IN | 1 |
| Tuon, FF | 1 |
| Winter Boldt, AB | 1 |
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| Prinsen, CF | 1 |
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| Pham, DAT | 1 |
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| Ahmad Zaid, FA | 1 |
| Cheah, YK | 1 |
| Becker, K | 1 |
| Vollbrecht, C | 2 |
| Koitzsch, U | 1 |
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| Fassunke, J | 1 |
| Huss, S | 2 |
| Nuernberg, P | 1 |
| Heukamp, LC | 2 |
| Buettner, R | 2 |
| Odenthal, M | 1 |
| Altmueller, J | 1 |
| Merkelbach-Bruse, S | 2 |
| Søes, S | 1 |
| Sørensen, BS | 1 |
| Alsner, J | 1 |
| Overgaard, J | 1 |
| Hager, H | 4 |
| Hansen, LL | 4 |
| Kristensen, LS | 2 |
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| Wong, SQ | 1 |
| Li, J | 2 |
| Dobrovic, A | 1 |
| Assadi, M | 1 |
| Lamerz, J | 1 |
| Jarutat, T | 2 |
| Farfsing, A | 1 |
| Paul, H | 1 |
| Gierke, B | 1 |
| Breitinger, E | 1 |
| Templin, MF | 1 |
| Essioux, L | 1 |
| Arbogast, S | 2 |
| Venturi, M | 1 |
| Pawlak, M | 1 |
| Langen, H | 1 |
| Schindler, T | 1 |
| Mäki-Nevala, S | 2 |
| Kaur Sarhadi, V | 1 |
| Tuononen, K | 2 |
| Lagström, S | 2 |
| Ellonen, P | 2 |
| Rönty, M | 2 |
| Wirtanen, A | 2 |
| Knuuttila, A | 2 |
| Knuutila, S | 2 |
| Walter, RF | 1 |
| Mairinger, FD | 1 |
| Wohlschlaeger, J | 1 |
| Worm, K | 1 |
| Ting, S | 1 |
| Schmid, KW | 1 |
| Hager, T | 1 |
| Donnarumma, F | 1 |
| Végvári, Á | 1 |
| Rezeli, M | 1 |
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| Haupt, K | 1 |
| Babitzki, G | 1 |
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| David, K | 1 |
| Juhl, H | 1 |
| Speit, G | 1 |
| Linsenmeyer, R | 1 |
| Duong, G | 1 |
| Bausinger, J | 1 |
| Warford, A | 1 |
| Akbar, H | 1 |
| Riberio, D | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| DETECT: Defining the Target Volume for Endoluminal Radiation Boosting in Patients With Rectal Cancer[NCT04927897] | 50 participants (Anticipated) | Observational | 2022-08-16 | Recruiting | |||
| Phase II Trial of Pemetrexed and Bevacizumab for Recurrent Ovarian and Primary Peritoneal Carcinoma[NCT00868192] | Phase 2 | 38 participants (Actual) | Interventional | 2008-05-31 | Completed | ||
| Environmental and Genetic Determinants of NPC[NCT01257100] | 3,500 participants (Actual) | Observational | 2010-12-08 | Terminated (stopped due to Determined not to be Human Subject Research) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Overall response rate = complete response + partial response~Complete response = disappearance of all target and non-target lesions and no evidence of new lesions documented by two disease assessments at least 4 weeks apart.~Partial response = at least a 30% decrease in the sum of the longest dimensions (LD) of all target measurable lesions taking as reference the baseline sum of LD. There can be non unequivocal progression of non-target lesions and no new lesions." (NCT00868192)
Timeframe: 6 months
| Intervention | percentage of participants (Number) |
|---|---|
| Pemetrexed and Bevacizumab | 41 |
OS = observed length of time from entry into the study to death or date of last contact (NCT00868192)
Timeframe: 12 months
| Intervention | percentage of participants (Number) |
|---|---|
| Pemetrexed and Bevacizumab | 79 |
OS = observed length of time from entry into the study to death or date of last contact (NCT00868192)
Timeframe: Median follow-up was 25.7 months (range 3.0-47.2 months)
| Intervention | months (Median) |
|---|---|
| Pemetrexed and Bevacizumab | 25.7 |
PFS = Period from study entry until disease progression, death, or date of last contact (NCT00868192)
Timeframe: 6 months
| Intervention | percentage of participants (Number) |
|---|---|
| Pemetrexed and Bevacizumab | 56 |
PFS = Period from study entry until disease progression, death, or date of last contact (NCT00868192)
Timeframe: Median follow-up was 25.7 months (range 3.0-47.2 months)
| Intervention | months (Median) |
|---|---|
| Pemetrexed and Bevacizumab | 7.9 |
A CA-125 response was defined as at least a 50% reduction in CA-125 levels from a pretreatment sample following guidelines described by the Gynecological Cancer Intergroup. (NCT00868192)
Timeframe: 6 months
| Intervention | participants (Number) | ||
|---|---|---|---|
| 50% CA-125 response | 75% CA-125 response | No CA-125 response | |
| Pemetrexed and Bevacizumab | 17 | 8 | 2 |
OS = observed length of time from entry into the study to death or date of last contact (NCT00868192)
Timeframe: Median follow-up was 25.7 months (range 3.0-47.2 months)
| Intervention | months (Median) | ||
|---|---|---|---|
| Platinum-free interval of <6 months | Platinum-free interval of 6-12 months | Platinum-free interval of >12 months | |
| Pemetrexed and Bevacizumab | 16.7 | 24.9 | 28.0 |
PFS = Period from study entry until disease progression, death, or date of last contact (NCT00868192)
Timeframe: Median follow-up was 25.7 months (range 3.0-47.2 months)
| Intervention | months (Median) | ||
|---|---|---|---|
| Platinum-free interval of <6 months | Platinum-free interval of 6-12 months | Platinum-free interval of >12 months | |
| Pemetrexed and Bevacizumab | 6.7 | 4.7 | 16.8 |
As measured by RECIST criteria (NCT00868192)
Timeframe: 6 months
| Intervention | participants (Number) | |||
|---|---|---|---|---|
| Complete response | Partial response | Stable disease | Progressive disease | |
| Pemetrexed and Bevacizumab | 0 | 14 | 18 | 2 |
Detailed serious adverse events and other adverse events are shown in the adverse event module of the results. (NCT00868192)
Timeframe: 6 months
| Intervention | percentage of participants (Number) | ||||
|---|---|---|---|---|---|
| Grade 3/4 hematologic toxicity | Most common non-hematologic toxicity - fatigue | Grade 3 renal toxicity | Gastrointestinal toxicity | Subsequently developed hematologic malignancies | |
| Pemetrexed and Bevacizumab | 53 | 94 | 6 | 91 | 6 |
12 reviews available for formaldehyde and Lung Neoplasms
| Article | Year |
|---|---|
Formalin-Fixed and Paraffin-Embedded Samples for Next Generation Sequencing: Problems and Solutions.
Topics: DNA, Neoplasm; ErbB Receptors; Formaldehyde; High-Throughput Nucleotide Sequencing; Humans; Lung Neo | 2021 |
Expert opinion on NSCLC small specimen biomarker testing - Part 1: Tissue collection and management.
Topics: Biomarkers; Carcinoma, Non-Small-Cell Lung; Expert Testimony; Fixatives; Formaldehyde; Humans; Lung | 2022 |
Occupational exposure to formaldehyde and risk of lung cancer: A systematic review and meta-analysis.
Topics: Adult; Female; Formaldehyde; Humans; Lung Neoplasms; Male; Occupational Diseases; Occupational Expos | 2020 |
Clinical value of miR-145-5p in NSCLC and potential molecular mechanism exploration: A retrospective study based on GEO, qRT-PCR, and TCGA data.
Topics: Carcinoma, Non-Small-Cell Lung; Computational Biology; Databases, Genetic; Formaldehyde; Humans; Lun | 2017 |
Antigen retrieval, blocking, detection and visualisation systems in immunohistochemistry: a review and practical evaluation of tyramide and rolling circle amplification systems.
Topics: Animals; Antibodies; Antigens; Antigens, CD20; Breast Neoplasms; Colonic Neoplasms; Female; Formalde | 2014 |
Nasal responses to air pollutants.
Topics: Air Pollutants; Air Pollutants, Occupational; Airway Resistance; Chromates; Cilia; Formaldehyde; Hum | 1984 |
Formation and occurrence of bis(chloromethyl)ether and its prevention in the chemical industry.
Topics: Air Pollutants, Occupational; Animals; Bis(Chloromethyl) Ether; Carcinogens; Chemical Industry; Chem | 1982 |
Formaldehyde exposure and respiratory cancer--a meta-analysis of the epidemiologic evidence.
Topics: Epidemiologic Methods; Formaldehyde; Humans; Lung Neoplasms; Occupational Diseases; Occupational Exp | 1993 |
Oils and cancer.
Topics: 2-Naphthylamine; Benzo(a)pyrene; Carcinogens; Chlorine Compounds; Esophageal Neoplasms; Ethanolamine | 1997 |
Reactive chemicals and cancer.
Topics: Acrylonitrile; Air Pollutants; Animals; Bis(Chloromethyl) Ether; Butadienes; Carcinogens; Cohort Stu | 1997 |
Indoor air pollutants. A literature review.
Topics: Air Pollution, Indoor; Asbestos; Asphyxia; Carbon Monoxide; Cardiovascular Diseases; Formaldehyde; H | 1991 |
Epidemiologic evidence on the relationship between formaldehyde exposure and cancer.
Topics: Brain Neoplasms; Colorectal Neoplasms; Environmental Exposure; Formaldehyde; Humans; Leukemia; Lung | 1990 |
3 trials available for formaldehyde and Lung Neoplasms
| Article | Year |
|---|---|
N1 lymph node detection in lymph node harvesting in non-small cell lung cancer: Formaldehyde exposure is a drawback?
Topics: Carcinoma, Non-Small-Cell Lung; Formaldehyde; Humans; Lung Neoplasms; Lymph Node Excision; Lymph Nod | 2023 |
Comparison of two methods to extract DNA from formalin-fixed, paraffin-embedded tissues and their impact on EGFR mutation detection in non-small cell lung carcinoma.
Topics: Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; DNA; ErbB Receptors; Forma | 2014 |
Development of a programmed cell death ligand-1 immunohistochemical assay validated for analysis of non-small cell lung cancer and head and neck squamous cell carcinoma.
Topics: Algorithms; Antibodies, Monoclonal; Antineoplastic Agents; Area Under Curve; B7-H1 Antigen; Biomarke | 2016 |
187 other studies available for formaldehyde and Lung Neoplasms
| Article | Year |
|---|---|
Choice of fixative is crucial to successful immunohistochemical detection of phosphoproteins in paraffin-embedded tumor tissues.
Topics: Animals; Biomarkers, Tumor; Breast Neoplasms; Colonic Neoplasms; Data Interpretation, Statistical; F | 2009 |
Non-radioactive localization of nucleic acids by direct in situ PCR and in situ RT-PCR in paraffin-embedded sections.
Topics: Base Sequence; Cell Line; Deoxyribonucleases; DNA; Endopeptidase K; Formaldehyde; Genes, p53; Humans | 1995 |
Development of a novel ALK rearrangement screening test for non-small cell lung cancers.
Topics: Adult; Aged; Aged, 80 and over; Anaplastic Lymphoma Kinase; Base Sequence; Carcinoma, Non-Small-Cell | 2021 |
Response to clinical evaluation of the effectiveness of fusion-induced asymmetric transcription assay-based reverse transcription droplet digital PCR for ALK detection in formalin-fixed paraffin-embedded samples from lung cancer.
Topics: Formaldehyde; Humans; Lung Neoplasms; Paraffin Embedding; Polymerase Chain Reaction; Receptor Protei | 2022 |
Comparison of Multi-Gene Testing Data Between Fresh and Formalin-Fixed Specimens From Core Needle Biopsy in Patients With NSCLC.
Topics: Adult; Aged; Aged, 80 and over; Biopsy, Large-Core Needle; Carcinoma, Non-Small-Cell Lung; DNA Mutat | 2021 |
A rare epidermal growth factor receptor (EGFR) gene mutation in small cell lung carcinoma patients.
Topics: Carcinoma, Non-Small-Cell Lung; DNA Mutational Analysis; ErbB Receptors; Female; Formaldehyde; Human | 2022 |
Validation of a DNA-Based Next-Generation Sequencing Test for Molecular Diagnostic Variant and Fusion Detection in Formalin-Fixed, Paraffin-Embedded Tissue Specimens and Liquid Biopsy Plasma/Cell-Free DNA Samples.
Topics: Cell-Free Nucleic Acids; DNA; Female; Formaldehyde; High-Throughput Nucleotide Sequencing; Humans; L | 2022 |
PPARgamma agonism inhibits progression of premalignant lesions in a murine lung squamous cell carcinoma model.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Desmoglein 3; Epithelial-Mesenchy | 2022 |
Rapid intraoperative Ki-67 immunohistochemistry for lung cancer using non-contact alternating current electric field mixing.
Topics: Carcinoma, Non-Small-Cell Lung; Formaldehyde; Humans; Immunohistochemistry; Ki-67 Antigen; Lung Neop | 2022 |
Deep targeted sequencing of cytological tumor cells using whole genome amplification.
Topics: DNA; DNA Copy Number Variations; Formaldehyde; Genomics; High-Throughput Nucleotide Sequencing; Huma | 2023 |
High tumor hexokinase-2 expression promotes a pro-tumorigenic immune microenvironment by modulating CD8+/regulatory T-cell infiltration.
Topics: Adenocarcinoma of Lung; B7-H1 Antigen; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Carcinoma, Sq | 2022 |
Cell pellet from fixative medium of transbronchial lung biopsy sample improves lung cancer ancillary test.
Topics: Biopsy; Carcinoma, Non-Small-Cell Lung; Fixatives; Formaldehyde; Humans; Lung; Lung Neoplasms; Mutat | 2023 |
Cell pellet from fixative medium of transbronchial lung biopsy sample improves lung cancer ancillary test.
Topics: Biopsy; Carcinoma, Non-Small-Cell Lung; Fixatives; Formaldehyde; Humans; Lung; Lung Neoplasms; Mutat | 2023 |
Cell pellet from fixative medium of transbronchial lung biopsy sample improves lung cancer ancillary test.
Topics: Biopsy; Carcinoma, Non-Small-Cell Lung; Fixatives; Formaldehyde; Humans; Lung; Lung Neoplasms; Mutat | 2023 |
Cell pellet from fixative medium of transbronchial lung biopsy sample improves lung cancer ancillary test.
Topics: Biopsy; Carcinoma, Non-Small-Cell Lung; Fixatives; Formaldehyde; Humans; Lung; Lung Neoplasms; Mutat | 2023 |
Cell pellet from fixative medium of transbronchial lung biopsy sample improves lung cancer ancillary test.
Topics: Biopsy; Carcinoma, Non-Small-Cell Lung; Fixatives; Formaldehyde; Humans; Lung; Lung Neoplasms; Mutat | 2023 |
Cell pellet from fixative medium of transbronchial lung biopsy sample improves lung cancer ancillary test.
Topics: Biopsy; Carcinoma, Non-Small-Cell Lung; Fixatives; Formaldehyde; Humans; Lung; Lung Neoplasms; Mutat | 2023 |
Cell pellet from fixative medium of transbronchial lung biopsy sample improves lung cancer ancillary test.
Topics: Biopsy; Carcinoma, Non-Small-Cell Lung; Fixatives; Formaldehyde; Humans; Lung; Lung Neoplasms; Mutat | 2023 |
Cell pellet from fixative medium of transbronchial lung biopsy sample improves lung cancer ancillary test.
Topics: Biopsy; Carcinoma, Non-Small-Cell Lung; Fixatives; Formaldehyde; Humans; Lung; Lung Neoplasms; Mutat | 2023 |
Cell pellet from fixative medium of transbronchial lung biopsy sample improves lung cancer ancillary test.
Topics: Biopsy; Carcinoma, Non-Small-Cell Lung; Fixatives; Formaldehyde; Humans; Lung; Lung Neoplasms; Mutat | 2023 |
A deep-learning model for transforming the style of tissue images from cryosectioned to formalin-fixed and paraffin-embedded.
Topics: Carcinoma, Non-Small-Cell Lung; Deep Learning; Formaldehyde; Humans; Lung Neoplasms; Paraffin Embedd | 2022 |
A reverse phase protein array based phospho-antibody characterization approach and its applicability for clinical derived tissue specimens.
Topics: Antibodies; Formaldehyde; Humans; Lung Neoplasms; Paraffin Embedding; Protein Array Analysis; Reprod | 2022 |
Tetrakis(4-pyridylphenyl)ethylene-based Zinc Metal-Organic Framework with Aggregation-Induced Chemiluminescence Emission on a Paper Platform for Formaldehyde Detection in Breath.
Topics: Ethylenes; Formaldehyde; Humans; Hydrogen Peroxide; Luminescence; Lung Neoplasms; Metal-Organic Fram | 2023 |
Targeted Quantitative Mass Spectrometry Analysis of Protein Biomarkers From Previously Stained Single Formalin-Fixed Paraffin-Embedded Tissue Sections.
Topics: B7-H1 Antigen; Biomarkers; Carcinoma, Non-Small-Cell Lung; Eosine Yellowish-(YS); Formaldehyde; Hema | 2023 |
Molecular patterns of egyptian patients with non-squamous non-small-cell lung cancers: a clinicopathological study.
Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Circulating Tumor DNA; Egypt; ErbB Receptors; Female; F | 2023 |
Detection of multiple types of cancer driver mutations using targeted RNA sequencing in non-small cell lung cancer.
Topics: Carcinoma, Non-Small-Cell Lung; Formaldehyde; High-Throughput Nucleotide Sequencing; Humans; Lung Ne | 2023 |
Panoramic Tissue Examination That Integrates 3-Dimensional Pathology Imaging and Gene Mutation: Potential Utility in Non-Small Cell Lung Cancer.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; DNA; Formaldehyde; Humans; Lung Neoplasms; Mutation; Paraff | 2023 |
CytoLyt fixation significantly inhibits MIB1 immunoreactivity whereas alternative Ki-67 clone 30-9 is not susceptible to the inhibition: Critical diagnostic implications.
Topics: Antibodies, Antinuclear; Antibodies, Monoclonal; Diagnosis, Differential; Formaldehyde; Humans; Immu | 2019 |
Multicenter Evaluation of the Fully Automated PCR-Based Idylla EGFR Mutation Assay on Formalin-Fixed, Paraffin-Embedded Tissue of Human Lung Cancer.
Topics: Automation, Laboratory; Carcinoma, Non-Small-Cell Lung; DNA Mutational Analysis; ErbB Receptors; For | 2019 |
EGFR Mutation Analysis in Non-small Cell Lung Carcinoma from Tissue Samples Using the Fully Automated Idylla™ qPCR System.
Topics: Bronchoalveolar Lavage Fluid; Carcinoma, Non-Small-Cell Lung; DNA Mutational Analysis; ErbB Receptor | 2019 |
Systematic evaluation of PAXgene® tissue fixation for the histopathological and molecular study of lung cancer.
Topics: Biomarkers, Tumor; Fixatives; Formaldehyde; High-Throughput Nucleotide Sequencing; Humans; Immunohis | 2020 |
Highly multiplexed immunofluorescence images and single-cell data of immune markers in tonsil and lung cancer.
Topics: Algorithms; Biomarkers, Tumor; Fluorescent Antibody Technique; Formaldehyde; Humans; Lung Neoplasms; | 2019 |
Clinical performance evaluation of the Idylla™ EGFR Mutation Test on formalin-fixed paraffin-embedded tissue of non-small cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Biopsy; Carcinoma, Non-Small-Cell Lung; DNA Mutational Analysis; Erb | 2020 |
Reference genome and annotation updates lead to contradictory prognostic predictions in gene expression signatures: a case study of resected stage I lung adenocarcinoma.
Topics: Adenocarcinoma; Formaldehyde; Gene Expression Profiling; Humans; Kaplan-Meier Estimate; Lung Neoplas | 2021 |
[Effect of storage time for non-small cell lung cancer FFPE samples on DNA detection using capture-based next-generation sequencing].
Topics: Carcinoma, Non-Small-Cell Lung; DNA; Formaldehyde; High-Throughput Nucleotide Sequencing; Humans; Lu | 2020 |
Comparative analysis of somatic variant calling on matched FF and FFPE WGS samples.
Topics: Biomarkers, Tumor; DNA, Neoplasm; Feasibility Studies; Formaldehyde; Gene Expression Profiling; Gene | 2020 |
Formalin fixation for optimal concordance of programmed death-ligand 1 immunostaining between cytologic and histologic specimens from patients with non-small cell lung cancer.
Topics: B7-H1 Antigen; Biopsy, Fine-Needle; Carcinoma, Non-Small-Cell Lung; Female; Formaldehyde; Humans; Im | 2021 |
Innovative Tumor Tissue Dissection Tool for Molecular Oncology Diagnostics.
Topics: Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Data Accuracy; Dissection; ErbB Receptors; Fix | 2021 |
Creation of Formalin-Fixed, Paraffin-Embedded 3D Lung Cancer Cellular Spheroids for the Optimization of Immunohistochemistry Staining Procedures.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Formaldehyde; Humans; Immunohistochemistry; Lung N | 2021 |
Confirming putative variants at ≤ 5% allele frequency using allele enrichment and Sanger sequencing.
Topics: Alleles; Carcinoma, Non-Small-Cell Lung; DNA, Neoplasm; Exome; Exome Sequencing; Fixatives; Formalde | 2021 |
Digital PCR detection of EGFR somatic mutations in non-small-cell lung cancer formalin fixed paraffin embedded samples.
Topics: Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Formaldehyde; Humans; Lung Neoplasms; Mutation; Para | 2021 |
Short report: Performance evaluation of the Idylla™ KRAS and EGFR mutation tests on paraffin-embedded cytological NSCLC samples.
Topics: Adenocarcinoma; Agar; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Fixatives; Formaldehyde; Ge | 2021 |
NGS Analysis of Liquid Biopsy (LB) and Formalin-Fixed Paraffin-Embedded (FFPE) Melanoma Samples Using Oncomine™ Pan-Cancer Cell-Free Assay.
Topics: Carcinoma, Non-Small-Cell Lung; Cell-Free Nucleic Acids; Female; Formaldehyde; High-Throughput Nucle | 2021 |
Diagnostic Utility of Gene Fusion Panel to Detect Gene Fusions in Fresh and Formalin-Fixed, Paraffin-Embedded Cancer Specimens.
Topics: Adenocarcinoma of Lung; Biomarkers, Tumor; Biopsy; Fixatives; Formaldehyde; Gene Fusion; High-Throug | 2021 |
Standardization of DNA amount for bisulfite conversion for analyzing the methylation status of LINE-1 in lung cancer.
Topics: Aged; Biomarkers, Tumor; Case-Control Studies; DNA Methylation; DNA, Neoplasm; Epigenesis, Genetic; | 2021 |
Effect of formalin fixation and tumour size in small-sized non-small-cell lung cancer: a prospective, single-centre study.
Topics: Adult; Aged; Aged, 80 and over; Artifacts; Carcinoma, Non-Small-Cell Lung; Cross-Sectional Studies; | 2017 |
Optimized expression-based microdissection of formalin-fixed lung cancer tissue.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; DNA; Formaldehyde; Humans; Immunohistochemistry; Lung; Lung | 2017 |
Long-lasting complete response status of advanced stage IV gall bladder cancer and colon cancer after combined treatment including autologous formalin-fixed tumor vaccine: two case reports.
Topics: Abdominal Wall; Cancer Vaccines; Colonic Neoplasms; Combined Modality Therapy; Female; Formaldehyde; | 2017 |
Differential N-glycan patterns identified in lung adenocarcinoma by N-glycan profiling of formalin-fixed paraffin-embedded (FFPE) tissue sections.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Biomarkers; Formaldehyde; Humans; Lung Neoplasms; Methods; P | 2018 |
Long non-coding RNA HOTTIP promotes BCL-2 expression and induces chemoresistance in small cell lung cancer by sponging miR-216a.
Topics: Animals; Apoptosis; Base Sequence; Carcinogenesis; Cell Line, Tumor; Drug Resistance, Neoplasm; Fema | 2018 |
Immunohistochemical Detection of Retinoblastoma Protein Phosphorylation in Human Tumor Samples.
Topics: Formaldehyde; Humans; Immunoenzyme Techniques; Lung Neoplasms; Paraffin Embedding; Phosphorylation; | 2018 |
Identification of novel mutations in FFPE lung adenocarcinomas using DEPArray sorting technology and next-generation sequencing.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; DNA Mutational Analysis; Fixatives; Flow Cytometry; Formalde | 2018 |
circRNA expression analysis in lung adenocarcinoma: comparison of paired fresh frozen and formalin-fixed paraffin-embedded specimens.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Aged; Cluster Analysis; Formaldehyde; Frozen Sections; Gene | 2018 |
Nonfouling, Encoded Hydrogel Microparticles for Multiplex MicroRNA Profiling Directly from Formalin-Fixed, Paraffin-Embedded Tissue.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Female; Formaldehyde; Humans; Hydrogels; | 2018 |
[Comparison of different massive parallel sequencing platforms for mutation profiling in formalin-fixed and paraffin-embedded samples].
Topics: Carcinoma, Non-Small-Cell Lung; China; Colorectal Neoplasms; Formaldehyde; High-Throughput Nucleotid | 2018 |
Reducing DNA damage by formaldehyde in liquid-based cytology preservation solutions to enable the molecular testing of lung cancer specimens.
Topics: A549 Cells; Adenocarcinoma; Cell Line, Tumor; Cytodiagnosis; DNA Damage; DNA Mutational Analysis; Er | 2018 |
Economic benefit-cost implications of the LNT model.
Topics: Carcinogens; Cost-Benefit Analysis; Environmental Restoration and Remediation; Formaldehyde; Governm | 2019 |
Performance of Oncomine Fusion Transcript kit for formalin-fixed, paraffin-embedded lung cancer specimens.
Topics: Anaplastic Lymphoma Kinase; Biomarkers, Tumor; Formaldehyde; Humans; In Situ Hybridization, Fluoresc | 2019 |
Detection of Epidermal Growth Factor Receptor (EGFR) Gene Mutation in Formalin Fixed Paraffin Embedded Tissue by Polymerase Chain Reaction-Single Strand Conformational Polymorphism (PCR-SSCP) in Non-Small Cell Lung Cancer in the Northeastern Region of Tha
Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Adult; Aged; Base Sequence; Biomarkers, Tumor; | 2019 |
Reliable Gene Expression Profiling from Small and Hematoxylin and Eosin-Stained Clinical Formalin-Fixed, Paraffin-Embedded Specimens Using the HTG EdgeSeq Platform.
Topics: Biomarkers, Tumor; Colorectal Neoplasms; Eosine Yellowish-(YS); Formaldehyde; Gene Expression Profil | 2019 |
A gene expression profile test to resolve head & neck squamous versus lung squamous cancers.
Topics: Adult; Aged; Algorithms; Area Under Curve; Bayes Theorem; Biomarkers, Tumor; Carcinoma, Squamous Cel | 2013 |
Detection of epidermal growth factor receptor mutations in formalin fixed paraffin embedded biopsies in Malaysian non-small cell lung cancer patients.
Topics: Biopsy; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Formaldehyde; Humans; Lung Neoplasms; Mutati | 2013 |
Deep ion sequencing of amplicon adapter ligated libraries: a novel tool in molecular diagnostics of formalin fixed and paraffin embedded tissues.
Topics: Alleles; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Formaldehyde; Humans; Lung; Lung Neoplasms; | 2013 |
Identification of accurate reference genes for RT-qPCR analysis of formalin-fixed paraffin-embedded tissue from primary non-small cell lung cancers and brain and lymph node metastases.
Topics: beta Karyopherins; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Formaldehyde; Gene Expression; G | 2013 |
Reducing sequence artifacts in amplicon-based massively parallel sequencing of formalin-fixed paraffin-embedded DNA by enzymatic depletion of uracil-containing templates.
Topics: Artifacts; Carcinoma, Squamous Cell; CpG Islands; DNA; Formaldehyde; High-Throughput Nucleotide Sequ | 2013 |
Multiple protein analysis of formalin-fixed and paraffin-embedded tissue samples with reverse phase protein arrays.
Topics: Blotting, Western; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Female; Formaldehyde; Humans; I | 2013 |
Mutated ephrin receptor genes in non-small cell lung carcinoma and their occurrence with driver mutations-targeted resequencing study on formalin-fixed, paraffin-embedded tumor material of 81 patients.
Topics: Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Codon, Nonsense; Fixatives; Formaldehyde; Humans; Lu | 2013 |
FFPE tissue as a feasible source for gene expression analysis--a comparison of three reference genes and one tumor marker.
Topics: Biomarkers, Tumor; Fixatives; Formaldehyde; Gene Expression; Gene Expression Profiling; Humans; Lung | 2013 |
Accessing microenvironment compartments in formalin-fixed paraffin-embedded tissues by protein expression analysis.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Biomarkers, Tumor; Cell Line, Tumor; Chromatography | 2013 |
Determination of phosphorylated proteins in tissue specimens requires high-quality samples collected under stringent conditions.
Topics: Biomarkers, Tumor; Biopsy; Blotting, Western; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Extr | 2014 |
Investigations on potential co-mutagenic effects of formaldehyde.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Alkylating Agents; Chromosome Aberrations; Comet | 2014 |
Identification of mRNAs and lincRNAs associated with lung cancer progression using next-generation RNA sequencing from laser micro-dissected archival FFPE tissue specimens.
Topics: Adenocarcinoma in Situ; Disease Progression; Formaldehyde; Gene Expression Profiling; Gene Ontology; | 2014 |
Mortality from lymphohematopoietic neoplasms and other causes in a cohort of laminated plastic workers exposed to formaldehyde.
Topics: Adult; Aged, 80 and over; Cohort Studies; Female; Formaldehyde; Head and Neck Neoplasms; Humans; Ita | 2014 |
Cytology specimens offer an effective alternative to formalin-fixed tissue as demonstrated by novel automated detection for ALK break-apart FISH testing and immunohistochemistry in lung adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Alcohols; Anaplastic Lymphoma Kinase; Cytodiagnosis; | 2014 |
Improved reproducibility in genome-wide DNA methylation analysis for PAXgene-fixed samples compared with restored formalin-fixed and paraffin-embedded DNA.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; CpG Islands; DNA; DNA Methylation; DNA, Neoplasm; Formaldehy | 2015 |
Clinical next-generation sequencing in patients with non-small cell lung cancer.
Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; DNA, Neoplasm; Feasibility Studies; Female; Fixatives; | 2015 |
Validation of a molecular and pathological model for five-year mortality risk in patients with early stage lung adenocarcinoma.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Aged; Female; Formaldehyde; Humans; Lung Neoplasms; Male; Ne | 2015 |
Application of tissue mesodissection to molecular cancer diagnostics.
Topics: Automation, Laboratory; Biopsy; Breast Neoplasms; DNA Mutational Analysis; Equipment Design; Female; | 2015 |
Flexible lab-tailored cut-offs for suitability of formalin-fixed tumor samples for diagnostic mutational analyses.
Topics: Colorectal Neoplasms; DNA Mutational Analysis; ErbB Receptors; Fixatives; Formaldehyde; Humans; Lung | 2015 |
Efficient Genotyping of KRAS Mutant Non-Small Cell Lung Cancer Using a Multiplexed Droplet Digital PCR Approach.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Clone Cells; DNA, Neoplasm; Formaldehyde; Gene Fre | 2015 |
PCR-sequencing is a complementary method to amplification refractory mutation system for EGFR gene mutation analysis in FFPE samples.
Topics: Carcinoma, Non-Small-Cell Lung; DNA Mutational Analysis; Formaldehyde; Genes, erbB-1; Humans; Lung N | 2015 |
The influence of DNA degradation in formalin-fixed, paraffin-embedded (FFPE) tissue on locus-specific methylation assessment by MS-HRM.
Topics: Carcinoma, Non-Small-Cell Lung; DNA Methylation; DNA, Neoplasm; Formaldehyde; Genetic Techniques; Hu | 2015 |
Multiplex Diagnosis of Oncogenic Fusion and MET Exon Skipping by Molecular Counting Using Formalin-Fixed Paraffin Embedded Lung Adenocarcinoma Tissues.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Exons; Formaldehyde; Gene Fusion; Humans; Lung Neoplasms; Pa | 2016 |
Allele-specific PCR method for identification of EGFR mutations in non-small cell lung cancer: formalin-fixed paraffin-embedded tissue versus fresh tissue.
Topics: Alleles; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Exons; Female; Formaldehyde; Humans; Lung N | 2016 |
MassARRAY, pyrosequencing, and PNA clamping for EGFR mutation detection in lung cancer tissue and cytological samples: a multicenter study.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; DNA Mutational Analysis; ErbB Receptors; Female; Formaldehyd | 2016 |
Performance comparison of two commercial human whole-exome capture systems on formalin-fixed paraffin-embedded lung adenocarcinoma samples.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; DNA, Neoplasm; Exome; Formaldehyde; Gene Expression Profilin | 2016 |
Cytology smears as excellent starting material for next-generation sequencing-based molecular testing of patients with adenocarcinoma of the lung.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Cytodiagnosis; Female; Formaldehyde; High-Throughput Nucleot | 2017 |
Unbiased Detection of Somatic Copy Number Aberrations in cfDNA of Lung Cancer Cases and High-Risk Controls with Low Coverage Whole Genome Sequencing.
Topics: DNA Copy Number Variations; DNA, Neoplasm; Formaldehyde; Genome, Human; High-Throughput Nucleotide S | 2016 |
A new classification method for MALDI imaging mass spectrometry data acquired on formalin-fixed paraffin-embedded tissue samples.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Biomarkers, Tumor; Carcinoma, Squamous Cell; Formaldehyde; H | 2017 |
High-throughput proteomic analysis of formalin-fixed paraffin-embedded tissue microarrays using MALDI imaging mass spectrometry.
Topics: Amino Acid Sequence; Fixatives; Formaldehyde; Humans; Lung Neoplasms; Molecular Sequence Data; Neopl | 2008 |
Proteomics--tissue and protein microarrays and antibody array: what information is provided?
Topics: Formaldehyde; Humans; Immunoassay; Lung Neoplasms; Neoplasm Proteins; Paraffin Embedding; Protein Ar | 2008 |
Reliability of chromogenic in situ hybridization for epidermal growth factor receptor gene copy number detection in non-small-cell lung carcinomas: a comparison with fluorescence in situ hybridization study.
Topics: Aged; Carcinoma, Non-Small-Cell Lung; Chromogenic Compounds; ErbB Receptors; Female; Formaldehyde; G | 2010 |
Identification of methods for use of formalin-fixed, paraffin-embedded tissue samples in RNA expression profiling.
Topics: Colonic Neoplasms; Formaldehyde; Freezing; Gene Expression Profiling; Humans; Lung Neoplasms; Oligon | 2009 |
Proteomics out of the archive: Two-dimensional electrophoresis and mass spectrometry using HOPE-fixed, paraffin-embedded tissues.
Topics: Adenocarcinoma; Biomarkers, Tumor; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squ | 2010 |
Quality assessment of DNA derived from up to 30 years old formalin fixed paraffin embedded (FFPE) tissue for PCR-based methylation analysis using SMART-MSP and MS-HRM.
Topics: Carcinoma, Non-Small-Cell Lung; DNA; DNA Methylation; Formaldehyde; Humans; Immunohistochemistry; Lu | 2009 |
Application of RT-PCR in formalin-fixed and paraffin-embedded lung cancer tissues.
Topics: Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Formaldehyde; Gene Express | 2010 |
Mutation detection of epidermal growth factor receptor and KRAS genes using the smart amplification process version 2 from formalin-fixed, paraffin-embedded lung cancer tissue.
Topics: Antineoplastic Agents; ErbB Receptors; Fixatives; Formaldehyde; Gefitinib; Humans; Lung Neoplasms; M | 2010 |
Simple quantitative analysis of asbestos body using the sediment of formalin injected into surgically resected lung cancers.
Topics: Adult; Aged; Aged, 80 and over; Asbestos; Clinical Laboratory Techniques; Female; Formaldehyde; Huma | 2010 |
Lung cancer and occupational exposures other than cotton dust and endotoxin among women textile workers in Shanghai, China.
Topics: Aged; Aged, 80 and over; China; Cotton Fiber; Dust; Endotoxins; Environmental Monitoring; Epidemiolo | 2011 |
Proteomic analysis of formalin-fixed, paraffin-embedded lung neuroendocrine tumor samples from hospital archives.
Topics: Biomarkers, Tumor; Chromatography, Liquid; Formaldehyde; Gene Expression Regulation, Neoplastic; Hos | 2011 |
Detection of ASPL/TFE3 fusion transcripts and the TFE3 antigen in formalin-fixed, paraffin-embedded tissue in a series of 18 cases of alveolar soft part sarcoma: useful diagnostic tools in cases with unusual histological features.
Topics: Adolescent; Adult; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Brain Neoplasms; Chi | 2011 |
Gene expression analysis using long-term preserved formalin-fixed and paraffin-embedded tissue of non-small cell lung cancer.
Topics: Carcinoma, Non-Small-Cell Lung; Fixatives; Formaldehyde; Gene Expression Profiling; Humans; Lung Neo | 2011 |
Comparison of formalin-free tissue fixatives: a proteomic study testing their application for routine pathology and research.
Topics: Biomarkers, Tumor; Blotting, Western; ErbB Receptors; Fixatives; Formaldehyde; Frozen Sections; Huma | 2011 |
Robust gene expression signature from formalin-fixed paraffin-embedded samples predicts prognosis of non-small-cell lung cancer patients.
Topics: Carcinoma, Non-Small-Cell Lung; Female; Formaldehyde; Gene Expression Profiling; Humans; Lung Neopla | 2011 |
Association between six environmental chemicals and lung cancer incidence in the United States.
Topics: Analysis of Variance; Arsenic; Butadienes; Carcinogens, Environmental; Environmental Exposure; Femal | 2011 |
Lung-targeted delivery system of curcumin loaded gelatin microspheres.
Topics: Animal Structures; Animals; Biological Availability; Calorimetry, Differential Scanning; Curcumin; D | 2011 |
Rinse fluid and imprint smear cytology of bronchial biopsies in diagnosis of lung tumors.
Topics: Adult; Aged; Biopsy; Bronchi; Bronchoalveolar Lavage Fluid; Cytodiagnosis; Early Diagnosis; Female; | 2012 |
Formalin fixation.
Topics: Fixatives; Formaldehyde; Humans; Lung Neoplasms; Neoplasm Proteins; Tissue Fixation | 2012 |
Proteomics?
Topics: Fixatives; Formaldehyde; Humans; Lung Neoplasms; Neoplasm Proteins; Tissue Fixation | 2012 |
Definition of a fluorescence in-situ hybridization score identifies high- and low-level FGFR1 amplification types in squamous cell lung cancer.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Carcinoma, Squamous Cell; Fixatives; Formaldehyde; Gene Ampl | 2012 |
Rapid detection of high-level oncogene amplifications in ultrasonic surgical aspirations of brain tumors.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Biopsy, Needle; Brain Neoplasms; Centrifugation; | 2012 |
Gene expression analysis in biomarker research and early drug development using function tested reverse transcription quantitative real-time PCR assays.
Topics: Animals; Biomarkers, Pharmacological; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Cell Line, | 2013 |
Influence of quercetin-rich food intake on microRNA expression in lung cancer tissues.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Aged; Carcinoma, Squamous Cell; Case-Control Studies; Diet; | 2012 |
Automation of genomic DNA isolation from formalin-fixed, paraffin-embedded tissues.
Topics: Automation; DNA; DNA Mutational Analysis; Formaldehyde; Genome; Genome, Human; Glyceraldehyde-3-Phos | 2012 |
Application of 2D-DIGE to formalin-fixed diseased tissue samples from hospital repositories: results from four case studies.
Topics: Animals; Biomarkers; Dogs; Formaldehyde; Humans; Lung Neoplasms; Paraffin Embedding; Proteins; Prote | 2013 |
Improved PCR amplification for molecular analysis using DNA from long-term preserved formalin-fixed, paraffin-embedded lung cancer tissue specimens.
Topics: DNA, Neoplasm; Formaldehyde; Humans; Lung Neoplasms; Paraffin Embedding; Polymerase Chain Reaction; | 2013 |
Assessment of the effect of occupational exposure to formaldehyde on the risk of lung cancer in two Canadian population-based case-control studies.
Topics: Aged; Canada; Case-Control Studies; Formaldehyde; Humans; Lung Neoplasms; Middle Aged; Occupational | 2013 |
Comparison of targeted next-generation sequencing (NGS) and real-time PCR in the detection of EGFR, KRAS, and BRAF mutations on formalin-fixed, paraffin-embedded tumor material of non-small cell lung carcinoma-superiority of NGS.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; DNA Mutational Analysis; ErbB Recept | 2013 |
Improvement in the quality of molecular analysis of EGFR in non-small-cell lung cancer detected by three rounds of external quality assessment.
Topics: Carcinoma, Non-Small-Cell Lung; Diagnostic Errors; DNA Mutational Analysis; ErbB Receptors; Fixative | 2013 |
Comparison of molecular testing methods for the detection of EGFR mutations in formalin-fixed paraffin-embedded tissue specimens of non-small cell lung cancer.
Topics: Carcinoma, Non-Small-Cell Lung; Formaldehyde; Genes, erbB-1; Genetic Techniques; Humans; Lung Neopla | 2013 |
The pattern of expression of Mn and Cu-Zn superoxide dismutase varies among squamous cell cancers of the lung, larynx, and oral cavity.
Topics: Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Case-Control Studies; Cytoplasm; Formaldehyde; Fr | 2002 |
Molecular biologic substaging of stage I NSCLC through immunohistochemistry performed on formalin-fixed, paraffin-embedded tissue.
Topics: Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Formaldehyde; Humans; Immunoenzyme Techniques; Lu | 2003 |
The urinary excretion of the formaldehydogenic steroids in patients with neoplasia of the respiratory or digestive system. 1. Bronchogenic carcinoma.
Topics: Carcinoma, Bronchogenic; Digestive System; Formaldehyde; Humans; Lung Neoplasms; Neoplasms; Steroids | 1959 |
Experimental carcinogenesis of the lung. Inhalation of gaseous formaldehyde or an aerosol of coal tar by C3H mice.
Topics: Aerosols; Animals; Carcinogenesis; Carcinogens; Carcinoma; Carcinoma, Squamous Cell; Coal Tar; Forma | 1963 |
Analysis of chromosome-11 aberrations in pulmonary and gastrointestinal carcinoids: an array comparative genomic hybridization-based study.
Topics: Adolescent; Adult; Aged; Carcinoid Tumor; Chromosome Aberrations; Chromosomes, Human, Pair 11; Femal | 2004 |
Re: Extended follow-up of a cohort of British chemical workers exposed to formaldehyde.
Topics: Carcinogens; Chemical Industry; Cohort Studies; Follow-Up Studies; Formaldehyde; Humans; Lung Neopla | 2004 |
Gene expression profiles in formalin-fixed, paraffin-embedded tissues obtained with a novel assay for microarray analysis.
Topics: Adenocarcinoma; Breast Neoplasms; Colonic Neoplasms; Female; Fixatives; Formaldehyde; Gene Expressio | 2004 |
Ultrasound-accelerated formalin fixation of tissue improves morphology, antigen and mRNA preservation.
Topics: Antigens; Blotting, Western; Cell Nucleus; Formaldehyde; Humans; Immunohistochemistry; In Situ Hybri | 2005 |
A rapid and sensitive enzymatic method for epidermal growth factor receptor mutation screening.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Chromatography, High Pressure Liquid; Deoxyribonuc | 2006 |
Antiprimer quenching-based real-time PCR and its application to the analysis of clinical cancer samples.
Topics: Apolipoproteins B; Breast Neoplasms; Colonic Neoplasms; DNA; DNA Primers; Female; Fixatives; Fluores | 2006 |
Large fragment Bst DNA polymerase for whole genome amplification of DNA from formalin-fixed paraffin-embedded tissues.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; DNA-Directed DNA Polymerase; DNA, Neoplasm; Formal | 2006 |
Effect of formalin fixation on tumor size determination in stage I non-small cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; Female; Formaldehyde; Humans; Lung N | 2007 |
Lung cancer risk from formaldehyde.
Topics: Animals; Formaldehyde; Humans; Lung Neoplasms; Male; Mice; Occupational Diseases; Physicians; Rats; | 1982 |
Formaldehyde in the British chemical industry. An occupational cohort study.
Topics: Chemical Industry; England; Environmental Exposure; Formaldehyde; Humans; Lung Neoplasms; Male; Nose | 1984 |
Formaldehyde process workers and lung cancer.
Topics: Formaldehyde; Humans; Lung Neoplasms; Male; Occupational Diseases; Probability | 1984 |
Cohort study of formaldehyde process workers.
Topics: Animals; Formaldehyde; Humans; Lung Neoplasms; Male; Nose Neoplasms; Occupational Diseases; Rats | 1984 |
Comparison of formalin- and acetone-fixation for immunohistochemical detection of carcinoembryonic antigen (CEA) and keratin.
Topics: Acetone; Adenocarcinoma; Carcinoembryonic Antigen; Formaldehyde; Histocytochemistry; Histological Te | 1983 |
The uncertain consequences of formaldehyde toxicity.
Topics: Aged; Animals; Carcinoma, Small Cell; Formaldehyde; Humans; Lung Neoplasms; Mice; Occupational Disea | 1981 |
[Exposure to formaldehyde and lung cancer in Danish physicians].
Topics: Aged; Denmark; Environmental Exposure; Female; Formaldehyde; Humans; Lung Neoplasms; Male; Middle Ag | 1982 |
Immune responses to naturally occurring rat sarcomas.
Topics: Animals; Antibodies, Neoplasm; Antibody Specificity; Cross Reactions; Formaldehyde; Immunization; Lu | 1981 |
ME1-antibody labelling of primary bronchogenic tumours and extrapulmonary malignancies.
Topics: Adenocarcinoma; Antibodies, Monoclonal; Antibody Specificity; Carcinoma, Bronchogenic; Formaldehyde; | 1994 |
Detection of DNA mutations in acid formalin-fixed paraffin-embedded archival tumor specimens by polymerase chain reaction-single strand conformation polymorphism analysis.
Topics: Base Sequence; Carcinoma, Non-Small-Cell Lung; DNA; Fixatives; Formaldehyde; Genes, p53; Humans; Lun | 1995 |
Comments on the Blair and Stewart comments on the Sterling and Weinkam analysis of data from the National Cancer Institute Formaldehyde Study.
Topics: Formaldehyde; Healthy Worker Effect; Humans; Lung Neoplasms; Occupational Diseases; Risk Factors | 1995 |
Mortality of iron foundry workers. III. Lung cancer case-control study.
Topics: Aged; Case-Control Studies; Cohort Studies; Formaldehyde; Humans; Logistic Models; Lung Neoplasms; M | 1994 |
Mortality from respiratory cancers (including lung cancer) among workers employed in formaldehyde industries.
Topics: Adult; Aged; Air Pollutants, Occupational; Cause of Death; Cohort Studies; Female; Formaldehyde; Hum | 1994 |
Improved method of preparation of inflated-fixed lung for radiologic-pathologic correlation.
Topics: Adult; Animals; Dogs; Formaldehyde; Humans; Immunohistochemistry; Infant; Lung; Lung Neoplasms; Poly | 1994 |
Epidermal growth factor receptor expression in squamous cell lung carcinomas: an immunohistochemical and gene analysis in formalin-fixed, paraffin-embedded material.
Topics: Base Sequence; Carcinoma, Squamous Cell; DNA, Neoplasm; ErbB Receptors; Formaldehyde; Gene Amplifica | 1993 |
A cohort study of workers exposed to formaldehyde in the British chemical industry: an update.
Topics: Chemical Industry; Cohort Studies; Follow-Up Studies; Formaldehyde; Humans; Lung Neoplasms; Male; Ne | 1993 |
Preimmunization of mice with formalinized extracellular antigens of melanoma in combination with IL-2 and surgical resection increased survival and tumor control in metastatic melanoma model.
Topics: Animals; Antigens, Neoplasm; Combined Modality Therapy; Extracellular Space; Female; Formaldehyde; I | 1993 |
K-ras genotypes and prognosis in non-small-cell lung cancer.
Topics: Aged; Alleles; Base Sequence; Carcinoma, Non-Small-Cell Lung; Female; Formaldehyde; Genes, ras; Geno | 1995 |
A universal method for the mutational analysis of K-ras and p53 gene in non-small-cell lung cancer using formalin-fixed paraffin-embedded tissue.
Topics: Base Sequence; Blotting, Southern; Carcinoma, Non-Small-Cell Lung; DNA Mutational Analysis; DNA Prim | 1995 |
The prognostic value of NCAM, p53 and cyclin D1 in resected non-small cell lung cancer.
Topics: Antibodies, Monoclonal; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Cyclin D1; Cyclins; Femal | 1996 |
Amplification of human beta-actin gene by the reverse transcriptase-polymerase chain reaction: implications for assessment of RNA from formalin-fixed, paraffin-embedded material.
Topics: Actins; Artifacts; Base Composition; Base Sequence; Biomarkers; Blotting, Southern; DNA Primers; DNA | 1996 |
Lung cancer mortality among workers in formaldehyde industries.
Topics: Female; Formaldehyde; Humans; Lung Neoplasms; Male; Occupational Diseases; Proportional Hazards Mode | 1996 |
Mortality among chemical workers in a factory where formaldehyde was used.
Topics: Chemical Industry; Cohort Studies; Connecticut; Formaldehyde; Humans; Lung Neoplasms; Male; Nasophar | 1996 |
Differential expression of N-cadherin in pleural mesotheliomas and E-cadherin in lung adenocarcinomas in formalin-fixed, paraffin-embedded tissues.
Topics: Adenocarcinoma; Antibodies, Monoclonal; Biomarkers; Cadherins; Diagnosis, Differential; Formaldehyde | 1997 |
Modified formalin and methanol fixation methods for molecular biological and morphological analyses.
Topics: Breast; Breast Neoplasms; Colon; Colonic Neoplasms; DNA; Fixatives; Formaldehyde; Gastric Mucosa; Hu | 1997 |
Human neuroblastoma demonstrating clonal evolution in vivo.
Topics: Child, Preschool; Clone Cells; Formaldehyde; Humans; In Situ Hybridization, Fluorescence; Kidney Neo | 1998 |
Alterations of CDKN2 (MTS1/p16INK4A) gene in paraffin-embedded tumor tissues of human stomach, lung, cervix and liver cancers.
Topics: Adenocarcinoma; Carcinoma, Hepatocellular; Cyclin-Dependent Kinase Inhibitor p16; Female; Formaldehy | 1998 |
Discrimination between genotoxicity and cytotoxicity for the induction of DNA double-strand breaks in cells treated with aldehydes and diepoxides.
Topics: Aldehydes; Alkylating Agents; Carcinogenicity Tests; Carcinogens; Cell Line; Cell Survival; DNA Dama | 1999 |
Assessment of DNA content in formalin-fixed, paraffin-embedded tissue of lung cancer by laser scanning cytometer.
Topics: Aneuploidy; Diploidy; DNA, Neoplasm; Fixatives; Flow Cytometry; Formaldehyde; Freezing; Humans; Imag | 1999 |
Monoclonal antibody MA454 reveals a heterogeneous expression pattern of MAGE-1 antigen in formalin-fixed paraffin embedded lung tumours.
Topics: Antibodies, Monoclonal; Antigens, Neoplasm; Formaldehyde; Gene Expression; Humans; Immunohistochemis | 2000 |
[The estimation of the effectiveness of GRF glue in the respiratory].
Topics: Aged; Bronchi; Drug Combinations; Evaluation Studies as Topic; Female; Formaldehyde; Gelatin; Humans | 2001 |
Detection of the Mr 110,000 lung resistance-related protein LRP/MVP with monoclonal antibodies.
Topics: Animals; Antibodies, Monoclonal; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small | 2001 |
[Are we hunting the wrong villain in the cigarette?].
Topics: Acrolein; Bronchi; Bronchial Neoplasms; Carcinogens; Cyanides; Formaldehyde; Humans; Lung Neoplasms; | 1978 |
Studies on lung tumours. III. Oxidative metabolism of dimethylnitrosamine by rodent and human lung tissue.
Topics: Aged; Animals; Carbon Dioxide; Cricetinae; Dimethylnitrosamine; Female; Formaldehyde; Formates; Huma | 1975 |
Proliferating cell nuclear antigen (PCNA) expression in formalin-fixed tissue of non-small cell lung carcinoma.
Topics: Carcinoma, Non-Small-Cell Lung; Formaldehyde; Humans; Lung Neoplasms; Mitotic Index; Nuclear Protein | 1992 |
Lung cancer mortality among industrial workers exposed to formaldehyde: a Poisson regression analysis of the National Cancer Institute Study.
Topics: Adult; Air Pollutants, Occupational; Chemical Industry; Cohort Studies; Formaldehyde; Humans; Lung N | 1992 |
A reanalysis of the National Cancer Institute study on lung cancer mortality among industrial workers exposed to formaldehyde.
Topics: Adult; Cohort Studies; Environmental Exposure; Female; Formaldehyde; Humans; Lung Neoplasms; Male; M | 1992 |
Dichloromethane (methylene chloride): metabolism to formaldehyde and formation of DNA-protein cross-links in B6C3F1 mice and Syrian golden hamsters.
Topics: Animals; Carcinogens; Cricetinae; Cross-Linking Reagents; DNA; Formaldehyde; Glutathione Transferase | 1992 |
Complementary reactivities of anti-carcinoembryonic antigen and antitumor-associated glycoprotein 72 monoclonal antibodies in lung carcinomas.
Topics: Adenocarcinoma; Antibodies, Monoclonal; Antigens, Neoplasm; Carcinoembryonic Antigen; Carcinoma, Sma | 1990 |
Histochemical heterogeneity of human mast cells: disease-related differences in mast cell subsets recovered by bronchoalveolar lavage.
Topics: Acetates; Acetic Acid; Adult; Aged; Aged, 80 and over; Alveolitis, Extrinsic Allergic; Bronchoalveol | 1990 |
Comparison of epidermal growth factor receptor expression in lung cancer by immunohistochemical staining of both frozen and formalin fixed specimens.
Topics: Cytological Techniques; ErbB Receptors; Formaldehyde; Freezing; Humans; Lung Neoplasms; Nitrogen | 1991 |
Preservation of cluster 1 small cell lung cancer antigen in zinc-formalin fixative and its application to immunohistological diagnosis.
Topics: Antibodies, Monoclonal; Antigens, Neoplasm; Carcinoma, Small Cell; Fixatives; Formaldehyde; Humans; | 1990 |
Environmental contaminants and low-level cancer risks: perceptions and scientific strategies.
Topics: Asbestos; Environmental Exposure; Formaldehyde; Heating; Humans; Lung Neoplasms; Radon; Risk Factors | 1990 |
Formaldehyde exposure and respiratory cancer among woodworkers--an update.
Topics: Case-Control Studies; Female; Finland; Formaldehyde; Humans; Laryngeal Neoplasms; Lung Neoplasms; Ma | 1990 |
In vitro studies of aldehyde effects related to human respiratory carcinogenesis.
Topics: Acrolein; Aldehydes; Bronchi; Calcium; Cell Division; Cell Membrane; Cell Survival; Cells, Cultured; | 1990 |
Mortality from lung cancer among workers employed in formaldehyde industries.
Topics: Cohort Studies; Formaldehyde; Humans; Lung Neoplasms; Male; Occupational Diseases; Prevalence; Risk; | 1990 |
Effects of several commonly used fixatives on DNA and total nuclear protein analysis by flow cytometry.
Topics: Adenocarcinoma; Breast Neoplasms; Carcinoma, Squamous Cell; Colonic Neoplasms; DNA; Fixatives; Flow | 1989 |
Reanalysis of lung cancer mortality in a National Cancer Institute Study on "Mortality among industrial workers exposed to formaldehyde".
Topics: Adult; Aged; Aged, 80 and over; Formaldehyde; Humans; Lung Neoplasms; Middle Aged; Multivariate Anal | 1989 |
Comments on the reanalysis of the National Cancer Institute study of workers exposed to formaldehyde.
Topics: Adult; Cohort Studies; Environmental Exposure; Formaldehyde; Humans; Lung Neoplasms; Male; Middle Ag | 1989 |
Did formaldehyde cause lung cancer?
Topics: Environmental Exposure; Formaldehyde; Humans; Lung Neoplasms; Occupational Diseases | 1989 |
Cancer mortality among workers in the Tuscan tanning industry.
Topics: Adult; Benzidines; Chromates; Formaldehyde; Humans; Italy; Kidney Neoplasms; Lung Neoplasms; Male; M | 1989 |
Formaldehyde and lung cancer.
Topics: Formaldehyde; Humans; Lung Neoplasms; Male; Occupational Diseases; Respiratory Tract Diseases; Unite | 1985 |
Formaldehyde, lung cancer, and bronchitis.
Topics: Adult; Aged; Bronchitis; Carcinogens, Environmental; Formaldehyde; Humans; Lung Neoplasms; Male; Mid | 1986 |
Reanalysis of lung cancer mortality in a National Cancer Institute study on mortality among industrial workers exposed to formaldehyde.
Topics: Adult; Aged; Cohort Studies; Female; Formaldehyde; Humans; Lung Neoplasms; Male; Middle Aged; Nation | 1988 |
Mortality among industrial workers exposed to formaldehyde.
Topics: Adult; Environmental Exposure; Female; Formaldehyde; Hodgkin Disease; Humans; Industry; Leukemia; Lu | 1986 |
Exposure to formaldehyde and cancer mortality in a cohort of workers producing resins.
Topics: Adolescent; Adult; Aged; Chemical Industry; Follow-Up Studies; Formaldehyde; Humans; Lung Neoplasms; | 1986 |
Contribution of formaldehyde to respiratory cancer.
Topics: Air Pollutants; Air Pollutants, Occupational; Animals; Carcinogens; Formaldehyde; Humans; Lung Neopl | 1986 |
[The environment and cancer].
Topics: Animals; Asbestos; Carcinogens, Environmental; Carcinoma, Squamous Cell; Formaldehyde; Humans; Lung | 1985 |
Formaldehyde poses little risk, study says.
Topics: Environmental Exposure; Formaldehyde; Humans; Lung Neoplasms; National Institutes of Health (U.S.); | 1986 |
Antitumor effect of intralesional injection with formalin-fixed Toxoplasma gondii organisms on Lewis lung carcinoma in Toxoplasma-infected mice.
Topics: Animals; BCG Vaccine; Carcinoma; Dose-Response Relationship, Immunologic; Female; Formaldehyde; Hype | 1985 |
[Causes of death of pathologists--the possible effect of formaldehyde].
Topics: Aged; Cardiovascular Diseases; Environmental Exposure; Female; Formaldehyde; Germany, West; Humans; | 1985 |
Formaldehyde exposure and respiratory and related cancers. A case-referent study among Finnish woodworkers.
Topics: Adult; Aged; Finland; Formaldehyde; Humans; Lung Neoplasms; Male; Middle Aged; Occupational Diseases | 1985 |
Alpha-(N)-formylheteroaromatic thiosemicarbazones. Inhibition of tumor-derived ribonucleoside diphosphate reductase and correlation with in vivo antitumor activity.
Topics: Alcohol Oxidoreductases; Animals; Antineoplastic Agents; Carcinoma; Cell Line; Dose-Response Relatio | 1974 |