formaldehyde has been researched along with Leukemia in 67 studies
paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors conducted meta-analyses of the epidemiological literature on formaldehyde exposure and risk of leukemia and risk of nasopharyngeal cancer." | 8.86 | Epidemiological studies of formaldehyde exposure and risk of leukemia and nasopharyngeal cancer: a meta-analysis. ( Bachand, AM; Montgomery, RR; Mundt, DJ; Mundt, KA, 2010) |
| "Formaldehyde exposures are common, and data linking these exposures to leukemia have been mixed and controversial." | 8.86 | Formaldehyde and leukemia: an updated meta-analysis and evaluation of bias. ( Schwilk, E; Smith, AH; Smith, MT; Steinmaus, C; Zhang, L, 2010) |
| "A recently published human study suggested that exposure to formaldehyde (FA) at the workplace might induce leukemia-specific aneuploidies (monosomy 7 and trisomy 8) in cultured myeloid progenitor cells." | 7.78 | Analysis of leukemia-specific aneuploidies in cultured myeloid progenitor cells in the absence and presence of formaldehyde exposure. ( Kuehner, S; Schlaier, M; Schwarz, K; Speit, G, 2012) |
| "Recent scientific debate has focused on the potential for inhaled formaldehyde to cause lymphohematopoietic cancers, particularly leukemias, in humans." | 7.77 | Is exposure to formaldehyde in air causally associated with leukemia?--A hypothesis-based weight-of-evidence analysis. ( Bailey, LA; Goodman, JE; Hamade, AK; Mayfield, D; Rhomberg, LR, 2011) |
| " Apart from some isolated exceptions, relative risks were close to the null, and there was little evidence for dose-response relations for any of the LHM." | 6.48 | Critical review and synthesis of the epidemiologic evidence on formaldehyde exposure and risk of leukemia and other lymphohematopoietic malignancies. ( Boffetta, P; Checkoway, H; Mundt, DJ; Mundt, KA, 2012) |
| "Formaldehyde is a naturally occurring biological compound that is present in tissues, cells, and bodily fluids." | 6.42 | The implausibility of leukemia induction by formaldehyde: a critical review of the biological evidence on distant-site toxicity. ( Casanova, M; Heck, Hd, 2004) |
| " Among exposed workers, peripheral blood cell counts were significantly lowered in a manner consistent with toxic effects on the bone marrow and leukemia-specific chromosome changes were significantly elevated in myeloid blood progenitor cells." | 5.36 | Occupational exposure to formaldehyde, hematotoxicity, and leukemia-specific chromosome changes in cultured myeloid progenitor cells. ( Alter, BP; Azuma, M; Blair, A; Fraumeni, JF; Freeman, LB; Galvan, N; Ge, Y; Guo, W; Hauptmann, M; Hayes, RB; Hua, M; Huang, H; Hubbard, AE; Ji, Z; Kim, S; Lan, Q; Li, L; Li, S; Liu, S; Moore, LE; Qiu, C; Rappaport, SM; Reiss, B; Rothman, N; Ruan, X; Shen, M; Smith, MT; Stewart, P; Tang, X; Vermeulen, R; Xie, Y; Xin, KX; Xiong, J; Zhang, L, 2010) |
| "The authors conducted meta-analyses of the epidemiological literature on formaldehyde exposure and risk of leukemia and risk of nasopharyngeal cancer." | 4.86 | Epidemiological studies of formaldehyde exposure and risk of leukemia and nasopharyngeal cancer: a meta-analysis. ( Bachand, AM; Montgomery, RR; Mundt, DJ; Mundt, KA, 2010) |
| "Formaldehyde exposures are common, and data linking these exposures to leukemia have been mixed and controversial." | 4.86 | Formaldehyde and leukemia: an updated meta-analysis and evaluation of bias. ( Schwilk, E; Smith, AH; Smith, MT; Steinmaus, C; Zhang, L, 2010) |
| "The United States Environmental Protection Agency (EPA) recently proposed a hypothetical mode of action (MOA) to explain how inhaled formaldehyde (FA) might induce leukemia, lymphoma and a variety of other lymphohematopoietic (LHP) malignancies in occupationally exposed workers." | 4.84 | Is inhalation exposure to formaldehyde a biologically plausible cause of lymphohematopoietic malignancies? ( Golden, R; Natelson, E; Pyatt, D, 2008) |
| "Shortly after the International Agency for Research on Cancer (IARC) determined that formaldehyde causes leukemia, the United States Environmental Protection Agency (EPA) released its Draft IRIS Toxicological Review of Formaldehyde ("Draft IRIS Assessment"), also concluding that formaldehyde causes leukemia." | 3.88 | Six years after the NRC review of EPA's Draft IRIS Toxicological Review of Formaldehyde: Regulatory implications of new science in evaluating formaldehyde leukemogenicity. ( Boffetta, P; Dell, LD; Gentry, PR; Mundt, KA; Rodricks, JV, 2018) |
| "A possible relationship between exposure to formaldehyde and leukemia-particularly myeloid leukemia-as well as of lymphoid neoplasms has been debated and is still controversial." | 3.80 | Mortality from lymphohematopoietic neoplasms and other causes in a cohort of laminated plastic workers exposed to formaldehyde. ( La Vecchia, C; Pira, E; Romano, C; Verga, F, 2014) |
| "To further evaluate the association between formaldehyde and leukemia, we extended follow-up through 2008 for a cohort mortality study of 11,043 US formaldehyde-exposed garment workers." | 3.79 | Cohort mortality study of garment industry workers exposed to formaldehyde: update and internal comparisons. ( Hein, MJ; Meyers, AR; Pinkerton, LE, 2013) |
| "A recently published human study suggested that exposure to formaldehyde (FA) at the workplace might induce leukemia-specific aneuploidies (monosomy 7 and trisomy 8) in cultured myeloid progenitor cells." | 3.78 | Analysis of leukemia-specific aneuploidies in cultured myeloid progenitor cells in the absence and presence of formaldehyde exposure. ( Kuehner, S; Schlaier, M; Schwarz, K; Speit, G, 2012) |
| "Recent scientific debate has focused on the potential for inhaled formaldehyde to cause lymphohematopoietic cancers, particularly leukemias, in humans." | 3.77 | Is exposure to formaldehyde in air causally associated with leukemia?--A hypothesis-based weight-of-evidence analysis. ( Bailey, LA; Goodman, JE; Hamade, AK; Mayfield, D; Rhomberg, LR, 2011) |
| "Carcinogenesis is a complex process initiated by a mutation in DNA that may be caused by chemical carcinogens present in polluted environments and human diet." | 3.01 | Electrochemical and Optical Sensors for the Detection of Chemical Carcinogens Causing Leukemia. ( Kowalczyk, A; Lejman, M; Zarychta, J; Zawitkowska, J, 2023) |
| "We review approaches for characterizing "peak" exposures in epidemiologic studies and methods for incorporating peak exposure metrics in dose-response assessments that contribute to risk assessment." | 2.61 | Peak Exposures in Epidemiologic Studies and Cancer Risks: Considerations for Regulatory Risk Assessment. ( Checkoway, H; Dell, LD; Gentry, PR; Lees, PSJ; Mundt, KA, 2019) |
| " Apart from some isolated exceptions, relative risks were close to the null, and there was little evidence for dose-response relations for any of the LHM." | 2.48 | Critical review and synthesis of the epidemiologic evidence on formaldehyde exposure and risk of leukemia and other lymphohematopoietic malignancies. ( Boffetta, P; Checkoway, H; Mundt, DJ; Mundt, KA, 2012) |
| "Three types of cancer were assessed: nasopharyngeal cancer, leukemia and sinonasal cancer." | 2.44 | [Assessment of carcinogenicity of formaldehyde based on the newest literature data]. ( Kupczewska-Dobecka, M, 2007) |
| "Chemically induced leukemia is a well-studied phenomenon with benzene and a number of cancer chemotherapeutic drugs recognized as capable of causing this effect." | 2.43 | Formaldehyde as a potential human leukemogen: an assessment of biological plausibility. ( Golden, R; Pyatt, D; Shields, PG, 2006) |
| "Formaldehyde is a naturally occurring biological compound that is present in tissues, cells, and bodily fluids." | 2.42 | The implausibility of leukemia induction by formaldehyde: a critical review of the biological evidence on distant-site toxicity. ( Casanova, M; Heck, Hd, 2004) |
| "Sulfuric acid appears to cause laryngeal cancer." | 2.40 | Reactive chemicals and cancer. ( Blair, A; Kazerouni, N, 1997) |
| " Finally, we compare a new bottom-up slope estimate of the risk of rat nasal cancer with conventional top-down estimates obtained with empirical dose-response modeling of rat nasal cancer bioassay data." | 1.43 | The bottom-up approach to bounding potential low-dose cancer risks from formaldehyde: An update. ( Starr, TB; Swenberg, JA, 2016) |
| "Benzene is an established myeloid leukemogen and probable lymphomagen." | 1.43 | Comparison of hematological alterations and markers of B-cell activation in workers exposed to benzene, formaldehyde and trichloroethylene. ( Bassig, BA; Blair, A; Freeman, LE; Ge, Y; Guo, W; Hayes, RB; Hosgood, HD; Hu, W; Huang, H; Ji, Z; Lan, Q; Li, G; Li, L; Purdue, MP; Qiu, C; Rappaport, SM; Reiss, B; Rothman, N; Shen, M; Smith, MT; Tang, X; Vermeulen, R; Wu, B; Xie, Y; Yin, S; Yue, F; Zhang, L, 2016) |
| ", 2009) and documentation provided in the draft IRIS profile, we attempted to duplicate the reported inhalation unit risk values and address the NAS Committee's questions regarding application of the appropriate dose-response model." | 1.43 | The need for transparency and reproducibility in documenting values for regulatory decision making and evaluating causality: The example of formaldehyde. ( Allen, BC; Gentry, PR; Mundt, KA; Van Landingham, C, 2016) |
| "Formaldehyde is a well-studied chemical and effects from inhalation exposures have been extensively characterized in numerous controlled studies with human volunteers, including asthmatics and other sensitive individuals, which provide a rich database on exposure concentrations that can reliably produce the symptoms of sensory irritation." | 1.37 | Identifying an indoor air exposure limit for formaldehyde considering both irritation and cancer hazards. ( Golden, R, 2011) |
| " Among exposed workers, peripheral blood cell counts were significantly lowered in a manner consistent with toxic effects on the bone marrow and leukemia-specific chromosome changes were significantly elevated in myeloid blood progenitor cells." | 1.36 | Occupational exposure to formaldehyde, hematotoxicity, and leukemia-specific chromosome changes in cultured myeloid progenitor cells. ( Alter, BP; Azuma, M; Blair, A; Fraumeni, JF; Freeman, LB; Galvan, N; Ge, Y; Guo, W; Hauptmann, M; Hayes, RB; Hua, M; Huang, H; Hubbard, AE; Ji, Z; Kim, S; Lan, Q; Li, L; Li, S; Liu, S; Moore, LE; Qiu, C; Rappaport, SM; Reiss, B; Rothman, N; Ruan, X; Shen, M; Smith, MT; Stewart, P; Tang, X; Vermeulen, R; Xie, Y; Xin, KX; Xiong, J; Zhang, L, 2010) |
| "As to its efficacy of infection prevention, LAF decreased infection during remission induction from 113/100 to 28/100." | 1.27 | Infection prevention for patients with acute leukemia using laminar air flow rooms. ( Masaoka, T, 1986) |
| "Recent animal studies found nasal cancer among rats exposed to formaldehyde, but no excess of this tumor occurred in this study." | 1.27 | Mortality among industrial workers exposed to formaldehyde. ( Bales, R; Blair, A; Cubit, D; Gaffey, W; Kaplan, S; O'Berg, M; Stewart, P; Walrath, J; Ward, J, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (25.37) | 18.7374 |
| 1990's | 6 (8.96) | 18.2507 |
| 2000's | 9 (13.43) | 29.6817 |
| 2010's | 30 (44.78) | 24.3611 |
| 2020's | 5 (7.46) | 2.80 |
| Authors | Studies |
|---|---|
| DIAZ-RUBIO, M | 1 |
| RIOS MOZO, M | 1 |
| DIAZ-RUBIO GARCIA, M | 1 |
| Kowalczyk, A | 1 |
| Zarychta, J | 1 |
| Lejman, M | 1 |
| Zawitkowska, J | 1 |
| Zhao, Y | 1 |
| Magaña, LC | 1 |
| Cui, H | 1 |
| Huang, J | 1 |
| McHale, CM | 1 |
| Yang, X | 1 |
| Looney, MR | 1 |
| Li, R | 1 |
| Zhang, L | 7 |
| Dingler, FA | 1 |
| Wang, M | 1 |
| Mu, A | 1 |
| Millington, CL | 1 |
| Oberbeck, N | 1 |
| Watcham, S | 1 |
| Pontel, LB | 1 |
| Kamimae-Lanning, AN | 1 |
| Langevin, F | 1 |
| Nadler, C | 1 |
| Cordell, RL | 1 |
| Monks, PS | 1 |
| Yu, R | 1 |
| Wilson, NK | 1 |
| Hira, A | 1 |
| Yoshida, K | 1 |
| Mori, M | 1 |
| Okamoto, Y | 1 |
| Okuno, Y | 1 |
| Muramatsu, H | 1 |
| Shiraishi, Y | 1 |
| Kobayashi, M | 2 |
| Moriguchi, T | 1 |
| Osumi, T | 1 |
| Kato, M | 1 |
| Miyano, S | 1 |
| Ito, E | 1 |
| Kojima, S | 1 |
| Yabe, H | 1 |
| Yabe, M | 1 |
| Matsuo, K | 1 |
| Ogawa, S | 1 |
| Göttgens, B | 1 |
| Hodskinson, MRG | 1 |
| Takata, M | 1 |
| Patel, KJ | 1 |
| Gentry, R | 1 |
| Thompson, CM | 2 |
| Franzen, A | 1 |
| Salley, J | 1 |
| Albertini, R | 1 |
| Lu, K | 2 |
| Greene, T | 1 |
| Haley, L | 1 |
| Parimi, V | 1 |
| Jiang, L | 1 |
| Pallavajjala, A | 1 |
| Hardy, M | 1 |
| Yonescu, R | 1 |
| Morsberger, L | 1 |
| Stinnett, V | 1 |
| Long, P | 1 |
| Zou, YS | 1 |
| Gocke, CD | 1 |
| Mundt, KA | 8 |
| Gallagher, AE | 3 |
| Dell, LD | 5 |
| Natelson, EA | 2 |
| Boffetta, P | 6 |
| Gentry, PR | 6 |
| Rothman, N | 4 |
| Lan, Q | 4 |
| Smith, MT | 6 |
| Vermeulen, R | 4 |
| Pira, E | 2 |
| Romano, C | 2 |
| Vecchia, C | 1 |
| Rodricks, JV | 1 |
| Natelson, E | 2 |
| Goldstein, BD | 1 |
| Williams, RA | 1 |
| Checkoway, H | 2 |
| Lees, PSJ | 1 |
| Meyers, AR | 1 |
| Pinkerton, LE | 1 |
| Hein, MJ | 1 |
| Verga, F | 1 |
| La Vecchia, C | 1 |
| Bartels, S | 1 |
| Schipper, E | 1 |
| Kreipe, HH | 1 |
| Lehmann, U | 1 |
| Starr, TB | 1 |
| Swenberg, JA | 2 |
| Bassig, BA | 1 |
| Tang, X | 2 |
| Li, G | 1 |
| Hu, W | 1 |
| Guo, W | 2 |
| Purdue, MP | 1 |
| Yin, S | 1 |
| Rappaport, SM | 2 |
| Shen, M | 2 |
| Ji, Z | 2 |
| Qiu, C | 2 |
| Ge, Y | 2 |
| Hosgood, HD | 1 |
| Reiss, B | 2 |
| Wu, B | 1 |
| Xie, Y | 2 |
| Li, L | 2 |
| Yue, F | 1 |
| Freeman, LE | 2 |
| Blair, A | 5 |
| Hayes, RB | 3 |
| Huang, H | 2 |
| Soffritti, M | 1 |
| Tibaldi, E | 1 |
| Padovani, M | 1 |
| Hoel, DG | 1 |
| Giuliani, L | 1 |
| Bua, L | 1 |
| Lauriola, M | 1 |
| Falcioni, L | 1 |
| Manservigi, M | 1 |
| Manservisi, F | 1 |
| Belpoggi, F | 1 |
| Van Landingham, C | 1 |
| Allen, BC | 1 |
| Nakamura, J | 1 |
| Hecht, SS | 1 |
| Vandenberg, JJ | 1 |
| Sonawane, BR | 1 |
| Liu, S | 1 |
| Freeman, LB | 1 |
| Hubbard, AE | 1 |
| Hua, M | 1 |
| Galvan, N | 1 |
| Ruan, X | 1 |
| Alter, BP | 1 |
| Xin, KX | 1 |
| Li, S | 1 |
| Moore, LE | 1 |
| Kim, S | 1 |
| Azuma, M | 1 |
| Hauptmann, M | 1 |
| Xiong, J | 1 |
| Stewart, P | 2 |
| Fraumeni, JF | 1 |
| Bachand, AM | 1 |
| Mundt, DJ | 2 |
| Montgomery, RR | 1 |
| Collins, LB | 1 |
| Ru, H | 1 |
| Bermudez, E | 1 |
| Speit, G | 2 |
| Gelbke, HP | 1 |
| Pallapies, D | 1 |
| Morfeld, P | 1 |
| Schwilk, E | 1 |
| Smith, AH | 1 |
| Steinmaus, C | 1 |
| Borze, I | 1 |
| Guled, M | 1 |
| Musse, S | 1 |
| Raunio, A | 1 |
| Elonen, E | 1 |
| Saarinen-Pihkala, U | 1 |
| Karjalainen-Lindsberg, ML | 1 |
| Lahti, L | 1 |
| Knuutila, S | 1 |
| Grafström, RC | 1 |
| Rhomberg, LR | 1 |
| Bailey, LA | 1 |
| Goodman, JE | 1 |
| Hamade, AK | 1 |
| Mayfield, D | 1 |
| Golden, R | 3 |
| Kuehner, S | 1 |
| Schlaier, M | 1 |
| Schwarz, K | 1 |
| BERGOL'TS, VM | 1 |
| FINK, MA | 1 |
| RAUSCHER, FJ | 1 |
| KAPLAN, MA | 1 |
| BRADNER, WT | 1 |
| BUCKWALTER, FH | 1 |
| PINDELL, MH | 1 |
| Nelson, K | 1 |
| Collins, JJ | 2 |
| Lineker, GA | 1 |
| Heck, Hd | 1 |
| Casanova, M | 1 |
| Cogliano, VJ | 1 |
| Grosse, Y | 1 |
| Baan, RA | 1 |
| Straif, K | 1 |
| Secretan, MB | 1 |
| El Ghissassi, F | 1 |
| Pyatt, D | 2 |
| Shields, PG | 1 |
| Sul, D | 1 |
| Kupczewska-Dobecka, M | 1 |
| Nagao, T | 1 |
| Ozawa, A | 1 |
| Sasaki, S | 1 |
| Partanen, T | 1 |
| Kauppinen, T | 1 |
| Luukkonen, R | 1 |
| Hakulinen, T | 1 |
| Pukkala, E | 1 |
| Cruz, C | 1 |
| Suarez, L | 1 |
| Rivero, R | 1 |
| Kazerouni, N | 1 |
| Thorndike, J | 1 |
| Beck, WS | 1 |
| Hoover, EA | 1 |
| Mathes, LE | 1 |
| Rojko, JL | 1 |
| Schaller, JP | 1 |
| Olsen, RG | 1 |
| Marin, C | 1 |
| Lopez, NM | 1 |
| Szabuniewicz, M | 1 |
| Alvarez, L | 1 |
| España, W | 1 |
| Rodriguez, R | 1 |
| Lozano, O | 1 |
| Castanos, H | 1 |
| León, A | 1 |
| Horland, AA | 1 |
| Wolman, SR | 1 |
| Europa, DL | 1 |
| Wagner, L | 1 |
| Base, W | 1 |
| Wiesholzer, M | 1 |
| Sexl, V | 1 |
| Bognar, H | 1 |
| Worman, CP | 1 |
| Saracci, R | 1 |
| Stewart, PA | 1 |
| Shy, C | 1 |
| Pelstring, RJ | 1 |
| Hurtubise, PE | 1 |
| Swerdlow, SH | 1 |
| Stross, WP | 1 |
| Warnke, RA | 1 |
| Flavell, DJ | 1 |
| Flavell, SU | 1 |
| Simmons, D | 1 |
| Gatter, KC | 1 |
| Mason, DY | 1 |
| Masaoka, T | 1 |
| O'Berg, M | 1 |
| Gaffey, W | 1 |
| Walrath, J | 1 |
| Ward, J | 1 |
| Bales, R | 1 |
| Kaplan, S | 1 |
| Cubit, D | 1 |
| Levine, RJ | 1 |
| Májský, A | 1 |
| Davis, S | 1 |
| Boone, CW | 1 |
| Radin, R | 1 |
| Wade, MJ | 1 |
| Kleiner, G | 1 |
| Lüthgen, W | 1 |
| Friedel, H | 1 |
| Berger, J | 1 |
| Fischer, R | 1 |
| Hennekeuser, HH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Studies of Myeloid Progenitor Cells in Workers Exposed to Formaldehyde, a Putative Leukemogen[NCT01338285] | 94 participants (Actual) | Observational | 2006-06-10 | Completed | |||
| Environmental and Genetic Determinants of NPC[NCT01257100] | 3,500 participants (Actual) | Observational | 2010-12-08 | Terminated (stopped due to Determined not to be Human Subject Research) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
15 reviews available for formaldehyde and Leukemia
| Article | Year |
|---|---|
Electrochemical and Optical Sensors for the Detection of Chemical Carcinogens Causing Leukemia.
Topics: Carcinogenesis; Carcinogens; Formaldehyde; Humans; Leukemia; Neoplasms | 2023 |
Using mechanistic information to support evidence integration and synthesis: a case study with inhaled formaldehyde and leukemia.
Topics: Causality; Formaldehyde; Humans; Inhalation Exposure; Leukemia; Neoplasms; Respiratory Hypersensitiv | 2020 |
Does occupational exposure to formaldehyde cause hematotoxicity and leukemia-specific chromosome changes in cultured myeloid progenitor cells?
Topics: Adult; Aneuploidy; Chromosomes; Cross-Sectional Studies; Formaldehyde; Hazardous Substances; Humans; | 2017 |
Peak Exposures in Epidemiologic Studies and Cancer Risks: Considerations for Regulatory Risk Assessment.
Topics: Acrylonitrile; Air Pollutants; Benzene; Environmental Exposure; Epidemiologic Studies; Ethylene Oxid | 2019 |
Formaldehyde and leukemia: epidemiology, potential mechanisms, and implications for risk assessment.
Topics: DNA Adducts; Environmental Exposure; Environmental Pollutants; Formaldehyde; Humans; Leukemia; Mutag | 2010 |
Epidemiological studies of formaldehyde exposure and risk of leukemia and nasopharyngeal cancer: a meta-analysis.
Topics: Air Pollutants, Occupational; Epidemiologic Studies; Formaldehyde; Humans; Leukemia; Nasopharyngeal | 2010 |
Formaldehyde and leukemia: an updated meta-analysis and evaluation of bias.
Topics: Bias; Data Interpretation, Statistical; Formaldehyde; Humans; Leukemia; Occupational Exposure; Risk | 2010 |
Critical review and synthesis of the epidemiologic evidence on formaldehyde exposure and risk of leukemia and other lymphohematopoietic malignancies.
Topics: Case-Control Studies; Cohort Studies; Formaldehyde; Hematologic Neoplasms; Humans; Leukemia; Occupat | 2012 |
A review and meta-analysis of formaldehyde exposure and leukemia.
Topics: Data Interpretation, Statistical; Follow-Up Studies; Formaldehyde; Humans; Leukemia; Occupational Di | 2004 |
The implausibility of leukemia induction by formaldehyde: a critical review of the biological evidence on distant-site toxicity.
Topics: Administration, Inhalation; Animals; Bone Marrow; Carbon Radioisotopes; Cricetinae; Cross-Linking Re | 2004 |
Formaldehyde as a potential human leukemogen: an assessment of biological plausibility.
Topics: Animals; Carcinogens; Formaldehyde; Humans; Leukemia; Mutagens; Risk | 2006 |
[Assessment of carcinogenicity of formaldehyde based on the newest literature data].
Topics: Air Pollutants; Animals; Carcinogenicity Tests; Carcinogens; European Union; Formaldehyde; Humans; I | 2007 |
Is inhalation exposure to formaldehyde a biologically plausible cause of lymphohematopoietic malignancies?
Topics: Animals; Carcinogens, Environmental; Disease Models, Animal; Formaldehyde; Humans; Inhalation Exposu | 2008 |
Reactive chemicals and cancer.
Topics: Acrylonitrile; Air Pollutants; Animals; Bis(Chloromethyl) Ether; Butadienes; Carcinogens; Cohort Stu | 1997 |
Epidemiologic evidence on the relationship between formaldehyde exposure and cancer.
Topics: Brain Neoplasms; Colorectal Neoplasms; Environmental Exposure; Formaldehyde; Humans; Leukemia; Lung | 1990 |
52 other studies available for formaldehyde and Leukemia
| Article | Year |
|---|---|
[On the clinical aspects of "paraform" leukemias].
Topics: Formaldehyde; Humans; Leukemia; Polymers | 1961 |
Formaldehyde-induced hematopoietic stem and progenitor cell toxicity in mouse lung and nose.
Topics: Animals; Bone Marrow Cells; Carcinogens; Cells, Cultured; Formaldehyde; Hematopoietic Stem Cells; In | 2021 |
Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans.
Topics: Adolescent; Alcohol Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Aldehydes; Animals; Child; | 2020 |
Diagnostic Utility of Gene Fusion Panel to Detect Gene Fusions in Fresh and Formalin-Fixed, Paraffin-Embedded Cancer Specimens.
Topics: Adenocarcinoma of Lung; Biomarkers, Tumor; Biopsy; Fixatives; Formaldehyde; Gene Fusion; High-Throug | 2021 |
Response to letter to the editor of Carcinogenesis by Pira et al., 2017.
Topics: Biomarkers; Carcinogenesis; Formaldehyde; Humans; Leukemia; Respiratory Hypersensitivity | 2017 |
Hematologic and cytogenetic biomarkers of leukemia risk from formaldehyde exposure.
Topics: Biomarkers; Cytogenetic Analysis; Formaldehyde; Humans; Leukemia; Research Design; Respiratory Hyper | 2017 |
Six years after the NRC review of EPA's Draft IRIS Toxicological Review of Formaldehyde: Regulatory implications of new science in evaluating formaldehyde leukemogenicity.
Topics: Animals; Bone Marrow; Formaldehyde; Humans; Leukemia; Occupational Exposure; Risk Assessment; United | 2018 |
Formaldehyde, Hematotoxicity, and Chromosomal Changes-Letter.
Topics: Formaldehyde; Humans; Leukemia; Occupational Exposure | 2018 |
Formaldehyde, Hematotoxicity, and Chromosomal Changes-Response.
Topics: Formaldehyde; Humans; Leukemia; Occupational Exposure | 2018 |
Response to Dr. Bernard D. Goldstein's Letter to the Editor.
Topics: Chromosomes; Formaldehyde; Humans; Leukemia; Myeloid Progenitor Cells; Occupational Exposure | 2018 |
Mundt et al. paper: "Does occupational exposure to formaldehyde cause hematotoxicity and leukemia-specific chromosome changes in cultured myeloid progenitor cells?"
Topics: Chromosomes; Formaldehyde; Humans; Leukemia; Myeloid Progenitor Cells; Occupational Exposure | 2018 |
Economic benefit-cost implications of the LNT model.
Topics: Carcinogens; Cost-Benefit Analysis; Environmental Restoration and Remediation; Formaldehyde; Governm | 2019 |
Cohort mortality study of garment industry workers exposed to formaldehyde: update and internal comparisons.
Topics: Adult; Aged; Aged, 80 and over; Female; Follow-Up Studies; Formaldehyde; Georgia; Humans; Leukemia; | 2013 |
Mortality from lymphohematopoietic neoplasms and other causes in a cohort of laminated plastic workers exposed to formaldehyde.
Topics: Adult; Aged, 80 and over; Cohort Studies; Female; Formaldehyde; Head and Neck Neoplasms; Humans; Ita | 2014 |
Comprehensive Molecular Profiling of Archival Bone Marrow Trephines Using a Commercially Available Leukemia Panel and Semiconductor-Based Targeted Resequencing.
Topics: Artifacts; Bone Marrow; DNA Glycosylases; Formaldehyde; Humans; Leukemia; Mutation; Sequence Analysi | 2015 |
The bottom-up approach to bounding potential low-dose cancer risks from formaldehyde: An update.
Topics: Animals; Carcinogenicity Tests; Carcinoma; DNA Adducts; Dose-Response Relationship, Drug; Fixatives; | 2016 |
Comparison of hematological alterations and markers of B-cell activation in workers exposed to benzene, formaldehyde and trichloroethylene.
Topics: Adult; B-Lymphocytes; Benzene; Biomarkers, Tumor; China; Female; Formaldehyde; Hemolytic Agents; Hum | 2016 |
Synergism between sinusoidal-50 Hz magnetic field and formaldehyde in triggering carcinogenic effects in male Sprague-Dawley rats.
Topics: Animals; Carcinogens; Cocarcinogenesis; Female; Formaldehyde; Hematologic Neoplasms; Kaplan-Meier Es | 2016 |
The need for transparency and reproducibility in documenting values for regulatory decision making and evaluating causality: The example of formaldehyde.
Topics: Administration, Inhalation; Dose-Response Relationship, Drug; Formaldehyde; Hodgkin Disease; Humans; | 2016 |
Occupational exposure to formaldehyde, hematotoxicity, and leukemia-specific chromosome changes in cultured myeloid progenitor cells.
Topics: Adult; Aneuploidy; Blood Cell Count; Carcinogens; Cells, Cultured; Chromosomes, Human, Pair 7; Chrom | 2010 |
Distribution of DNA adducts caused by inhaled formaldehyde is consistent with induction of nasal carcinoma but not leukemia.
Topics: Animals; Chromatography, High Pressure Liquid; DNA Adducts; Formaldehyde; Inhalation Exposure; Leuke | 2010 |
Occupational exposure to formaldehyde, hematotoxicity and leukemia-specific chromosome changes in cultured myeloid progenitor cells.
Topics: Adult; Aneuploidy; Blood Cell Count; Chromosomes, Human, Pair 7; Chromosomes, Human, Pair 8; Formald | 2010 |
MicroRNA microarrays on archive bone marrow core biopsies of leukemias--method validation.
Topics: Biopsy; Bone Marrow; Formaldehyde; Gene Expression Profiling; Humans; Leukemia; MicroRNAs; Oligonucl | 2011 |
Considerations for the implausibility of leukemia induction by formaldehyde.
Topics: Aldehyde Oxidoreductases; Animals; DNA Adducts; Formaldehyde; Humans; Leukemia; Substrate Specificit | 2011 |
Is exposure to formaldehyde in air causally associated with leukemia?--A hypothesis-based weight-of-evidence analysis.
Topics: Air Pollutants; Animals; Carcinogens, Environmental; Causality; Confounding Factors, Epidemiologic; | 2011 |
Identifying an indoor air exposure limit for formaldehyde considering both irritation and cancer hazards.
Topics: Air Pollution, Indoor; Carcinoma; Formaldehyde; Humans; Inhalation Exposure; Irritants; Leukemia; Na | 2011 |
Analysis of leukemia-specific aneuploidies in cultured myeloid progenitor cells in the absence and presence of formaldehyde exposure.
Topics: Aneuploidy; Cells, Cultured; Formaldehyde; Humans; In Situ Hybridization, Fluorescence; Leukemia; My | 2012 |
[Carcinogenic chemicals and risk of hematopoietic neoplasms].
Topics: Alkylating Agents; Animals; Benzene; Formaldehyde; Humans; Leukemia; Thorium Dioxide; Topoisomerase | 2012 |
[Experimental studies on the etiology of human leukemias. II. Effect of formaldehyde, glycerin, high temperatures and radiations on human leukemia factor].
Topics: Animals; Formaldehyde; Glycerol; Humans; Leukemia; Radiation; Temperature | 1959 |
IMMUNE REACTIONS TO A MURINE LEUKEMIA VIRUS. I. INDUCTION OF IMMUNITY TO INFECTION WITH VIRUS IN THE NATURAL HOST.
Topics: Animals; Formaldehyde; Freund's Adjuvant; Leukemia; Leukemia Virus, Murine; Leukemia, Experimental; | 1964 |
ANTITUMOUR ACTIVITY OF N-(BETA,BETA'-DICHLORODIETHYLAMINOMETHYL)-TETRACYCLINE, 'TETRACYCLINE-MUSTARD'.
Topics: Adenocarcinoma; Animals; Formaldehyde; Injections, Intraperitoneal; Leukemia; Leukemia, Experimental | 1965 |
Formaldehyde link to cancer.
Topics: Air Pollutants; Formaldehyde; Humans; Industry; Leukemia; Occupational Diseases | 2003 |
Formaldehyde exposure and leukaemia.
Topics: Formaldehyde; Humans; Leukemia; Occupational Exposure | 2004 |
Meeting report: summary of IARC monographs on formaldehyde, 2-butoxyethanol, and 1-tert-butoxy-2-propanol.
Topics: Animals; Carcinogens, Environmental; Disinfectants; Ethylene Glycols; Fixatives; Formaldehyde; Human | 2005 |
Evaluation of toxicological monitoring markers using proteomic analysis.
Topics: Administration, Inhalation; Animals; Biomarkers; Blood Proteins; DNA Damage; Formaldehyde; Leukemia; | 2006 |
Maintenance of germ-free environment and its clinical utility.
Topics: Air Microbiology; Air Movements; Bacteria; Bacterial Infections; Decontamination; Dust; Environment, | 1983 |
Malignant lymphomas and leukemias, and exposures in the wood industry: an industry-based case-referent study.
Topics: Air Pollutants, Occupational; Dust; Formaldehyde; Humans; Leukemia; Logistic Models; Lymphoma; Male; | 1993 |
Improved detection of CD2 on formaldehyde-fixed non dehydrated cells.
Topics: CD2 Antigens; Fixatives; Formaldehyde; Humans; Immunophenotyping; Leukemia; Lymphoma | 1995 |
Production of formaldehyde from N5-methyltetrahydrofolate by normal and leukemic leukocytes.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alcohol Oxidoreductases; Chemical Phenome | 1977 |
Modifications of the immunofluorescence assay for feline leukemia virus group-specific antigens.
Topics: Animals; Antigens, Viral; Cat Diseases; Cats; Ethanol; Fluorescent Antibody Technique; Formaldehyde; | 1978 |
A new antiviral agent (P2) in the purpose of treatment of bovine leukemia.
Topics: Animals; Antiviral Agents; Ascorbic Acid; Cattle; Cattle Diseases; Female; Formaldehyde; Leukemia; L | 1978 |
Preparation and light-microscopic examination of fixed hematopoietic cells in soft agar.
Topics: Agar; Blood Cells; Bone Marrow Cells; Cells, Cultured; Culture Media; Formaldehyde; Histological Tec | 1978 |
Detection of BLT substrate-specific proteases in individual human peripheral blood leucocytes and bone marrow cells. Application of the method to the classification of leukaemia.
Topics: Antibodies, Monoclonal; Bone Marrow; Colonic Neoplasms; Diazonium Compounds; Formaldehyde; Granulocy | 1991 |
Flow-cytometric DNA analysis of hematopoietic and lymphoid proliferations: a comparison of fresh, formalin-fixed and B5-fixed tissues.
Topics: Cell Division; DNA; Fixatives; Flow Cytometry; Formaldehyde; Humans; Hyperplasia; Interphase; Leukem | 1990 |
Molecule detected in formalin fixed tissue by antibodies MT1, DF-T1, and L60 (Leu-22) corresponds to CD43 antigen.
Topics: Antibodies, Monoclonal; Antigens, CD; Antigens, Neoplasm; Blotting, Western; Fixatives; Flow Cytomet | 1989 |
Infection prevention for patients with acute leukemia using laminar air flow rooms.
Topics: Acute Disease; Bone Marrow Transplantation; Chlorhexidine; Cytomegalovirus Infections; Disinfection; | 1986 |
Mortality among industrial workers exposed to formaldehyde.
Topics: Adult; Environmental Exposure; Female; Formaldehyde; Hodgkin Disease; Humans; Industry; Leukemia; Lu | 1986 |
Formaldehyde, cancer, and social class.
Topics: Adult; Aged; Brain Neoplasms; Formaldehyde; Humans; Leukemia; Male; Middle Aged; Socioeconomic Facto | 1985 |
[Considerations on HL-A antigens and their isolation].
Topics: Anemia, Aplastic; Animals; Bromelains; Complement System Proteins; Cytotoxicity Tests, Immunologic; | 1974 |
Retention of significant antibody binding by surface antigens of feline leukemia cells (FLA) after fixation with formaldehyde and glutaraldehyde.
Topics: Aldehydes; Animals; Antibody Specificity; Antigen-Antibody Reactions; Binding Sites, Antibody; Cat D | 1974 |
[Simplification of the hematological diagnosis of bovine leukosis. I. Addition of formalin to saponin for erythrocytolysis].
Topics: Animals; Cattle; Cattle Diseases; Formaldehyde; Leukemia; Leukocyte Count; Saponins | 1971 |
[On the demonstration of thiaminpyrophosphatase ("Golgiphosphatase") in blood and bone marrow cells].
Topics: Blood Cells; Bone Marrow; Bone Marrow Cells; Calcium Chloride; Chlorides; Cytoplasmic Granules; Form | 1968 |