Page last updated: 2024-10-18

formaldehyde and Lesion of Sciatic Nerve

formaldehyde has been researched along with Lesion of Sciatic Nerve in 9 studies

paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy

Research Excerpts

ExcerptRelevanceReference
"Luteolin is a naturally occurring flavonoid with diverse pharmacological properties such as anti-inflammatory, antioxidant and anticancer."5.46Effects of luteolin and luteolin-morphine co-administration on acute and chronic pain and sciatic nerve ligated-induced neuropathy in mice. ( Abdollahzadeh, M; Golmakani, E; Hashemzaei, M; Iranshahi, M; Rezaee, R; Tabrizian, K, 2017)
"Ambroxol's effects were compared with those of gabapentin."5.33Ambroxol, a Nav1.8-preferring Na(+) channel blocker, effectively suppresses pain symptoms in animal models of chronic, neuropathic and inflammatory pain. ( Arndt, K; Gaida, W; Klinder, K; Weiser, T, 2005)
"The degree of allodynia was most marked following 10 min of irradiation."5.32Gabapentin reverses mechanical allodynia induced by sciatic nerve ischemia and formalin-induced nociception in mice. ( Berge, OG; Brodin, E; Flood, K; Gustafsson, H; Olgart, L; Stiller, CO, 2003)
"Luteolin is a naturally occurring flavonoid with diverse pharmacological properties such as anti-inflammatory, antioxidant and anticancer."1.46Effects of luteolin and luteolin-morphine co-administration on acute and chronic pain and sciatic nerve ligated-induced neuropathy in mice. ( Abdollahzadeh, M; Golmakani, E; Hashemzaei, M; Iranshahi, M; Rezaee, R; Tabrizian, K, 2017)
"Ambroxol's effects were compared with those of gabapentin."1.33Ambroxol, a Nav1.8-preferring Na(+) channel blocker, effectively suppresses pain symptoms in animal models of chronic, neuropathic and inflammatory pain. ( Arndt, K; Gaida, W; Klinder, K; Weiser, T, 2005)
"The degree of allodynia was most marked following 10 min of irradiation."1.32Gabapentin reverses mechanical allodynia induced by sciatic nerve ischemia and formalin-induced nociception in mice. ( Berge, OG; Brodin, E; Flood, K; Gustafsson, H; Olgart, L; Stiller, CO, 2003)
" Thus, studies on the prevention and management of chronic pain should focus on preemptive or long-term administration of NMDA receptor antagonists."1.32Effects of low-affinity NMDA receptor channel blockers in two rat models of chronic pain. ( Aliev, K; Belozertseva, IV; Bespalov, AY; Danysz, W; Malyshkin, AA; Medvedev, IO; Parsons, CG; Sevostianova, NY; Sukhotina, IA; Zvartau, EE, 2004)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (88.89)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kasukurthi, R1
Brenner, MJ1
Moore, AM1
Moradzadeh, A1
Ray, WZ1
Santosa, KB1
Mackinnon, SE1
Hunter, DA1
Hashemzaei, M1
Abdollahzadeh, M1
Iranshahi, M1
Golmakani, E1
Rezaee, R1
Tabrizian, K1
Hayashi, T1
Miyata, M1
Nagata, T1
Izawa, Y1
Kawakami, Y1
Vissers, K1
Adriaensen, H1
De Coster, R1
De Deyne, C1
Meert, TF1
Gustafsson, H1
Flood, K1
Berge, OG1
Brodin, E1
Olgart, L1
Stiller, CO1
Medvedev, IO1
Malyshkin, AA1
Belozertseva, IV1
Sukhotina, IA1
Sevostianova, NY1
Aliev, K1
Zvartau, EE1
Parsons, CG1
Danysz, W1
Bespalov, AY1
Gaida, W1
Klinder, K1
Arndt, K1
Weiser, T1
Hizue, M1
Pang, CH1
Yokoyama, M1
Akada, Y1
Mori, R1
Kato, Y1
Yamasaki, F1
Mochizuki, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Ambroxol on the Inflammatory Markers and Clinical Outcome of Patients With Diabetic Peripheral Neuropathy[NCT05558878]80 participants (Anticipated)Interventional2022-10-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

9 other studies available for formaldehyde and Lesion of Sciatic Nerve

ArticleYear
Transcardial perfusion versus immersion fixation for assessment of peripheral nerve regeneration.
    Journal of neuroscience methods, 2009, Nov-15, Volume: 184, Issue:2

    Topics: Animals; Artifacts; Axons; Cardiac Surgical Procedures; Disease Models, Animal; Dissection; Fixative

2009
Effects of luteolin and luteolin-morphine co-administration on acute and chronic pain and sciatic nerve ligated-induced neuropathy in mice.
    Journal of complementary & integrative medicine, 2017, Mar-01, Volume: 14, Issue:1

    Topics: Acute Disease; Analgesics; Animals; Chronic Pain; Disease Models, Animal; Drug Therapy, Combination;

2017
Intracerebroventricular fluvoxamine administration inhibited pain behavior but increased Fos expression in affective pain pathways.
    Pharmacology, biochemistry, and behavior, 2009, Volume: 91, Issue:3

    Topics: Affect; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Fluvoxamine; Formaldehy

2009
A chronic-constriction injury of the sciatic nerve reduces bilaterally the responsiveness to formalin in rats: a behavioral and hormonal evaluation.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:2

    Topics: Adrenocorticotropic Hormone; Animals; Behavior, Animal; Cold Temperature; Corticosterone; Formaldehy

2003
Gabapentin reverses mechanical allodynia induced by sciatic nerve ischemia and formalin-induced nociception in mice.
    Experimental neurology, 2003, Volume: 182, Issue:2

    Topics: Acetates; Amines; Analgesics; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Disease Models

2003
Effects of low-affinity NMDA receptor channel blockers in two rat models of chronic pain.
    Neuropharmacology, 2004, Volume: 47, Issue:2

    Topics: Animals; Chronic Disease; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Antagonists;

2004
Ambroxol, a Nav1.8-preferring Na(+) channel blocker, effectively suppresses pain symptoms in animal models of chronic, neuropathic and inflammatory pain.
    Neuropharmacology, 2005, Volume: 49, Issue:8

    Topics: Ambroxol; Amines; Analgesics; Animals; Behavior, Animal; Constriction, Pathologic; Cyclohexanecarbox

2005
Involvement of N-methyl-D-aspartate-type glutamate receptor epsilon1 and epsilon4 subunits in tonic inflammatory pain and neuropathic pain.
    Neuroreport, 2005, Oct-17, Volume: 16, Issue:15

    Topics: Animals; Formaldehyde; Inflammation; Ligation; Mice; Mice, Inbred C57BL; Mice, Knockout; Pain; Pain

2005
Analgesic properties of the novel compound M43068 in rat models of acute and neuropathic pain.
    European journal of pharmacology, 2005, Oct-31, Volume: 523, Issue:1-3

    Topics: Adrenergic alpha-Antagonists; Analgesics; Animals; Baclofen; Behavior, Animal; Disease Models, Anima

2005