formaldehyde has been researched along with Invasiveness, Neoplasm in 25 studies
paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy
| Excerpt | Relevance | Reference |
|---|---|---|
| "Restrained expression of miR-106a in gastric cancer cells significantly reduces their capacity of proliferation, migration and invasion." | 1.40 | MicroRNA-106a targets TIMP2 to regulate invasion and metastasis of gastric cancer. ( He, S; Lu, G; Lui, Y; Zhang, N; Zhao, L; Zhu, M, 2014) |
| "The level of brachyury expression in breast cancer cells was positively associated with their ability to invade the extracellular matrix, efficiently form mammospheres in vitro, and resist the cytotoxic effect of docetaxel." | 1.40 | Overexpression of the EMT driver brachyury in breast carcinomas: association with poor prognosis. ( Cavaliere, F; Cheng, Q; Costarelli, L; Fernando, RI; Ferroni, P; Guadagni, F; Hamilton, DH; Huang, B; Jochems, C; Litzinger, MT; Lyerly, HK; Palena, C; Roselli, M; Schlom, J; Spila, A; Tsang, KY, 2014) |
| "The heterogeneity among multiple ductal carcinoma in situ (DCIS) lesions within the same patient also diagnosed with invasive ductal carcinoma (IDC) has not been well evaluated, leaving research implications of intra-individual DCIS heterogeneity yet to be explored." | 1.40 | Identifying a highly-aggressive DCIS subgroup by studying intra-individual DCIS heterogeneity among invasive breast cancer patients. ( Cai, KQ; Chen, X; Daly, MB; Devarajan, K; Jiang, Z; Pape-Zambito, D; Patchefsky, A; Slater, CM; Wu, H, 2014) |
| "MiR-221 is over-expressed in human hepatocellular carcinoma (HCC), but its clinical significance and function in HCC remains uncertain." | 1.39 | Increased miR-221 expression in hepatocellular carcinoma tissues and its role in enhancing cell growth and inhibiting apoptosis in vitro. ( Chen, G; Dang, Y; Rong, M, 2013) |
| "However, breast cancer is a diverse disease and little is known about the relationships between miRNA expression, clinical outcome and tumour subtype." | 1.38 | Biological and prognostic associations of miR-205 and let-7b in breast cancer revealed by in situ hybridization analysis of micro-RNA expression in arrays of archival tumour tissue. ( Ali, HR; Bardwell, H; Blows, F; Caldas, C; Dawson, SJ; Jones, J; Pharoah, P; Quesne, JL; Warren, J, 2012) |
| "Ten palpable invasive breast carcinomas were resected and underwent immediate gross evaluation." | 1.38 | Delay to formalin fixation alters morphology and immunohistochemistry for breast carcinoma. ( Khoury, T, 2012) |
| "In patients with esophageal squamous cell carcinoma, there appears to be an inverse relationship between nm23-H1 gene product expression and lymphatic vessel invasion." | 1.31 | Expression of nm23-H1 gene product in esophageal squamous cell carcinoma and its association with vessel invasion and survival. ( Ayabe, T; Edagawa, M; Hara, M; Maeda, M; Matsuzaki, Y; Onitsuka, T; Shimizu, T; Tomita, M, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (16.00) | 18.2507 |
| 2000's | 3 (12.00) | 29.6817 |
| 2010's | 17 (68.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kalloger, SE | 1 |
| Karasinska, JM | 1 |
| Keung, MS | 1 |
| Thompson, DL | 1 |
| Ho, J | 1 |
| Chow, C | 1 |
| Gao, D | 1 |
| Topham, JT | 1 |
| Warren, C | 1 |
| Wong, HL | 1 |
| Lee, MK | 1 |
| Renouf, DJ | 1 |
| Schaeffer, DF | 1 |
| Soon, PS | 1 |
| Provan, PJ | 1 |
| Kim, E | 1 |
| Pathmanathan, N | 1 |
| Graham, D | 1 |
| Clarke, CL | 1 |
| Balleine, RL | 1 |
| Chin, SF | 1 |
| Santonja, A | 1 |
| Grzelak, M | 1 |
| Ahn, S | 1 |
| Sammut, SJ | 1 |
| Clifford, H | 1 |
| Rueda, OM | 1 |
| Pugh, M | 1 |
| Goldgraben, MA | 1 |
| Bardwell, HA | 1 |
| Cho, EY | 1 |
| Provenzano, E | 1 |
| Rojo, F | 1 |
| Alba, E | 1 |
| Caldas, C | 2 |
| Tabyaoui, I | 1 |
| Tahiri-Jouti, N | 1 |
| Serhier, Z | 1 |
| Bennani-Othmani, M | 1 |
| Sibai, H | 1 |
| Itri, M | 1 |
| Benchekroun, S | 1 |
| Zamiati, S | 1 |
| Zhu, M | 1 |
| Zhang, N | 1 |
| He, S | 1 |
| Lui, Y | 1 |
| Lu, G | 1 |
| Zhao, L | 1 |
| Zuo, P | 1 |
| Ma, Y | 1 |
| Huang, Y | 1 |
| Ye, F | 1 |
| Wang, P | 1 |
| Wang, X | 1 |
| Zhou, C | 1 |
| Lu, W | 1 |
| Kong, B | 1 |
| Xie, X | 1 |
| Palena, C | 1 |
| Roselli, M | 1 |
| Litzinger, MT | 1 |
| Ferroni, P | 1 |
| Costarelli, L | 1 |
| Spila, A | 1 |
| Cavaliere, F | 1 |
| Huang, B | 1 |
| Fernando, RI | 1 |
| Hamilton, DH | 1 |
| Jochems, C | 1 |
| Tsang, KY | 1 |
| Cheng, Q | 1 |
| Lyerly, HK | 1 |
| Schlom, J | 1 |
| Guadagni, F | 1 |
| Pape-Zambito, D | 1 |
| Jiang, Z | 1 |
| Wu, H | 1 |
| Devarajan, K | 1 |
| Slater, CM | 1 |
| Cai, KQ | 1 |
| Patchefsky, A | 1 |
| Daly, MB | 1 |
| Chen, X | 2 |
| Hagen, RM | 1 |
| Adamo, P | 1 |
| Karamat, S | 1 |
| Oxley, J | 1 |
| Aning, JJ | 1 |
| Gillatt, D | 1 |
| Persad, R | 1 |
| Ladomery, MR | 1 |
| Rhodes, A | 1 |
| Yan, SY | 1 |
| Hu, Y | 1 |
| Fan, JG | 1 |
| Tao, GQ | 1 |
| Lu, YM | 1 |
| Cai, X | 1 |
| Yu, BH | 1 |
| Du, YQ | 1 |
| Deftereos, G | 1 |
| Corrie, SR | 1 |
| Feng, Q | 1 |
| Morihara, J | 1 |
| Stern, J | 1 |
| Hawes, SE | 1 |
| Kiviat, NB | 1 |
| Quesne, JL | 1 |
| Jones, J | 1 |
| Warren, J | 1 |
| Dawson, SJ | 1 |
| Ali, HR | 1 |
| Bardwell, H | 1 |
| Blows, F | 1 |
| Pharoah, P | 1 |
| Yamamoto, S | 1 |
| Ibusuki, M | 1 |
| Yamamoto, Y | 1 |
| Fu, P | 1 |
| Fujiwara, S | 1 |
| Murakami, K | 1 |
| Iwase, H | 1 |
| Khoury, T | 1 |
| Gorman, BK | 1 |
| Kosarac, O | 1 |
| Chakraborty, S | 1 |
| Schwartz, MR | 1 |
| Mody, DR | 1 |
| He, C | 1 |
| Jiang, H | 1 |
| Geng, S | 1 |
| Sheng, H | 1 |
| Shen, X | 1 |
| Zhang, X | 1 |
| Zhu, S | 1 |
| Yang, C | 1 |
| Gao, H | 1 |
| Beltran, H | 1 |
| Yelensky, R | 1 |
| Frampton, GM | 1 |
| Park, K | 1 |
| Downing, SR | 1 |
| MacDonald, TY | 1 |
| Jarosz, M | 1 |
| Lipson, D | 1 |
| Tagawa, ST | 1 |
| Nanus, DM | 1 |
| Stephens, PJ | 1 |
| Mosquera, JM | 1 |
| Cronin, MT | 1 |
| Rubin, MA | 1 |
| Rong, M | 1 |
| Chen, G | 1 |
| Dang, Y | 1 |
| Selvarajan, S | 1 |
| Bay, BH | 1 |
| Choo, A | 1 |
| Chuah, KL | 1 |
| Sivaswaren, CR | 1 |
| Tien, SL | 1 |
| Wong, CY | 1 |
| Tan, PH | 1 |
| Roomi, MW | 1 |
| Roomi, N | 1 |
| Ivanov, V | 1 |
| Kalinovsky, T | 1 |
| Niedzwiecki, A | 1 |
| Rath, M | 1 |
| Piffkó, J | 1 |
| Bánkfalvi, A | 1 |
| Ofner, D | 1 |
| Berens, A | 1 |
| Tkotz, T | 1 |
| Joos, U | 1 |
| Böcker, W | 1 |
| Schmid, KW | 1 |
| Saenz-Santamaría, MC | 1 |
| McNutt, NS | 1 |
| Bogdany, JK | 1 |
| Shea, CR | 1 |
| Allison, RT | 1 |
| Best, T | 1 |
| Tomita, M | 1 |
| Ayabe, T | 1 |
| Matsuzaki, Y | 1 |
| Edagawa, M | 1 |
| Maeda, M | 1 |
| Shimizu, T | 1 |
| Hara, M | 1 |
| Onitsuka, T | 1 |
| Gijbels, MJ | 1 |
| Visser, JW | 1 |
| Solleveld, HA | 1 |
| Broerse, JJ | 1 |
| Zurcher, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| "A Randomized Multicenter Phase II Trial to Evaluate the Effectiveness of Selective Neoadjuvant Treatment According to Immunohistochemical Subtype for HER2 Negative Breast Cancer Patients"[NCT00432172] | Phase 2 | 189 participants (Actual) | Interventional | 2007-04-24 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Clinical Response Rate was measured according to the Response Evaluation Criteria in Solid Tumors (RECIST) Criteria for target lesions before surgery: Complete Response (CR), Disappearance of all target lesions; Partial Response (PR), >=30% decrease in the sum of the longest diameter of target lesions; Overall Response (OR) = CR + PR. (NCT00432172)
Timeframe: Up to week 24
| Intervention | Participants (Count of Participants) |
|---|---|
| Group 1 (Luminal A) Standard Treatment | 31 |
| Group 1 (Luminal A) Selective Treatment | 23 |
| Group 2 (Basal) Standard Treatment | 32 |
| Group 2 (Basal) Selective Treatment | 36 |
25 other studies available for formaldehyde and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Stroma vs epithelium-enhanced prognostics through histologic stratification in pancreatic ductal adenocarcinoma.
Topics: Carcinoma, Pancreatic Ductal; Cluster Analysis; Cohort Studies; Epithelial Cells; Formaldehyde; Gene | 2021 |
Profiling differential microRNA expression between in situ, infiltrative and lympho-vascular space invasive breast cancer: a pilot study.
Topics: Adult; Aged; Axilla; Blood Vessels; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Intraduc | 2018 |
Shallow whole genome sequencing for robust copy number profiling of formalin-fixed paraffin-embedded breast cancers.
Topics: Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; DNA; DNA Copy Number Variations; Female; | 2018 |
Immunohistochemical expression of CD44s in human neuroblastic tumors: Moroccan experience and highlights on current data.
Topics: Adolescent; Biomarkers, Tumor; Cell Differentiation; Chi-Square Distribution; Child; Child, Preschoo | 2013 |
MicroRNA-106a targets TIMP2 to regulate invasion and metastasis of gastric cancer.
Topics: Base Sequence; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Formaldehyde; Gene Knock | 2014 |
High GMFG expression correlates with poor prognosis and promotes cell migration and invasion in epithelial ovarian cancer.
Topics: Actins; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Movement; Cytoskeleton; Disease-Free S | 2014 |
Overexpression of the EMT driver brachyury in breast carcinomas: association with poor prognosis.
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Cell Line, Tumor; Epithelial-Mesenchymal Transitio | 2014 |
Identifying a highly-aggressive DCIS subgroup by studying intra-individual DCIS heterogeneity among invasive breast cancer patients.
Topics: Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Intraductal, Noninfiltrat | 2014 |
Quantitative analysis of ERG expression and its splice isoforms in formalin-fixed, paraffin-embedded prostate cancer samples: association with seminal vesicle invasion and biochemical recurrence.
Topics: Alternative Splicing; Exons; Formaldehyde; Gene Expression Regulation, Neoplastic; Humans; Immunohis | 2014 |
Clinicopathologic significance of HER-2/neu protein expression and gene amplification in gastric carcinoma.
Topics: Adenocarcinoma; Biomarkers, Tumor; China; Female; Fixatives; Formaldehyde; Gene Amplification; Gene | 2011 |
Expression of mir-21 and mir-143 in cervical specimens ranging from histologically normal through to invasive cervical cancer.
Topics: Cell Line, Tumor; Cervix Uteri; Female; Formaldehyde; Gene Expression Profiling; Gene Expression Reg | 2011 |
Biological and prognostic associations of miR-205 and let-7b in breast cancer revealed by in situ hybridization analysis of micro-RNA expression in arrays of archival tumour tissue.
Topics: Biomarkers, Tumor; Biopsy; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chi-Squa | 2012 |
Clinical relevance of Ki67 gene expression analysis using formalin-fixed paraffin-embedded breast cancer specimens.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Breast Neoplasms; Female; Formaldehyde; Gene Expr | 2013 |
Delay to formalin fixation alters morphology and immunohistochemistry for breast carcinoma.
Topics: Biomarkers; Breast Neoplasms; Female; Formaldehyde; Humans; Immunohistochemistry; Neoplasm Invasiven | 2012 |
Comparison of breast carcinoma prognostic/predictive biomarkers on cell blocks obtained by various methods: Cellient, formalin and thrombin.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Biopsy, Fine-Needle; Breast Neoplasms; Cytodiagno | 2012 |
Expression of c-Myc and Fas correlates with perineural invasion of pancreatic cancer.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Chi-Square Distribution; China; fas Receptor; Fem | 2012 |
Targeted next-generation sequencing of advanced prostate cancer identifies potential therapeutic targets and disease heterogeneity.
Topics: Androgen Antagonists; Antineoplastic Agents, Hormonal; Biopsy, Needle; Drug Resistance, Neoplasm; Ex | 2013 |
Increased miR-221 expression in hepatocellular carcinoma tissues and its role in enhancing cell growth and inhibiting apoptosis in vitro.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Apoptosis; Carcinoma, Hepatocellular; Caspase | 2013 |
Effect of fixation period on HER2/neu gene amplification detected by fluorescence in situ hybridization in invasive breast carcinoma.
Topics: Breast Neoplasms; Female; Fixatives; Formaldehyde; Gene Amplification; Genes, erbB-2; Humans; In Sit | 2002 |
Inhibitory effect of a mixture containing ascorbic acid, lysine, proline and green tea extract on critical parameters in angiogenesis.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Cell Line, Tumor; Cell Proli | 2005 |
Expression of p53 protein in oral squamous cell carcinomas and adjacent non-tumorous mucosa of the floor of the mouth: an archival immunohistochemical study using wet autoclave pretreatment for antigen retrieval.
Topics: Antibodies, Monoclonal; Antigens, Neoplasm; Carcinoma, Squamous Cell; Female; Fixatives; Follow-Up S | 1995 |
p53 expression is rare in cutaneous melanomas.
Topics: Aged; Antibodies, Monoclonal; Antigens, Neoplasm; Cell Division; Cell Nucleus; Fixatives; Formaldehy | 1995 |
p53, PCNA and Ki-67 expression in oral squamous cell carcinomas: the vagaries of fixation and microwave enhancement of immunocytochemistry.
Topics: Biomarkers, Tumor; Carcinoma, Squamous Cell; Cytoplasm; Disease Progression; Epithelial Cells; Ethan | 1998 |
Expression of nm23-H1 gene product in esophageal squamous cell carcinoma and its association with vessel invasion and survival.
Topics: Biomarkers, Tumor; Carcinoma, Squamous Cell; Esophageal Neoplasms; Female; Fixatives; Formaldehyde; | 2001 |
Flow cytometric DNA measurement and cytomorphometric analysis of formalin fixed rat mammary tumours.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinoma, Papillary; DNA, Neoplasm; Female; Flow Cytometry; Forma | 1991 |