Page last updated: 2024-10-18

formaldehyde and Hypesthesia

formaldehyde has been researched along with Hypesthesia in 7 studies

paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy

Hypesthesia: Absent or reduced sensitivity to cutaneous stimulation.

Research Excerpts

ExcerptRelevanceReference
"Although the magnitude of the hyperalgesia is dependent on the intensity of the conditioning stimulus, we find that the direction of effect is dependent on the effective test stimulus intensity, with lower-intensity stimuli leading to hyperalgesia and higher-intensity stimuli leading to hypoalgesia."1.51Conditioned pain modulation in rodents can feature hyperalgesia or hypoalgesia depending on test stimulus intensity. ( Austin, JS; Coderre, TJ; Diamond, L; George, N; Macintyre, LC; Martin, LJ; Meluban, L; Mogil, JS; Sotocinal, SG; Tansley, SN, 2019)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's1 (14.29)18.2507
2000's3 (42.86)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yatsuhashi, T1
Nakagawa, K1
Matsumoto, M1
Kasahara, M1
Igarashi, T1
Ichinohe, T1
Kaneko, Y1
Tansley, SN1
Macintyre, LC1
Diamond, L1
Sotocinal, SG1
George, N1
Meluban, L1
Austin, JS1
Coderre, TJ1
Martin, LJ1
Mogil, JS1
Brkić, A1
Gürkan-Köseoğlu, B1
Olgac, V1
Köseoğlu, BG1
Tanrikulu, S1
Sübay, RK1
Sencer, S1
Erişen, R1
Yücel, T1
Küçükay, S1
Kleier, DJ1
Averbach, RE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Multicenter Study Comparing Healing After Treatment With the Sonendo GentleWave™ System as Compared to a Traditional Root Canal Therapy Literature Control[NCT02285595]69 participants (Actual)Interventional2014-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With a PAI Score of < 3, = 3, or = 4 or 5

"The periapical index: A scoring system for radiographic assessment of apical periodontitis. Score of 1: Normal. Score of 2: Small changes in bone structure. Score of 3: Changes in bone structure with some mineral loss (bone loss). Score of 4: Periodontitis with well-defined radiolucent area (apical periodontitis). Score of 5: Severe Periodontitis with exacerbating features (apical periodontitis).~Healed is defined by absence of a radiographic indication of apical periodontitis (PAI <3) and absence of clinical signs and symptoms other than tenderness to percussion.~Healing is defined by a reduction of radiolucency (if radiolucency is present at Baseline) combined with the absence of clinical signs and symptoms other than tenderness to percussion." (NCT02285595)
Timeframe: 12 months

InterventionParticipants (Count of Participants)
PAI Score < 3PAI Score = 3PAI Score 4 or 5
GentleWave™ Treatment Group5130

Other Studies

7 other studies available for formaldehyde and Hypesthesia

ArticleYear
Inferior alveolar nerve paresthesia relieved by microscopic endodontic treatment.
    The Bulletin of Tokyo Dental College, 2003, Volume: 44, Issue:4

    Topics: Adult; Calcium Hydroxide; Cranial Nerve Injuries; Extravasation of Diagnostic and Therapeutic Materi

2003
Conditioned pain modulation in rodents can feature hyperalgesia or hypoalgesia depending on test stimulus intensity.
    Pain, 2019, Volume: 160, Issue:4

    Topics: Acetic Acid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Facial Pain; Formald

2019
Surgical approach to iatrogenic complications of endodontic therapy: a report of 2 cases.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2009, Volume: 107, Issue:5

    Topics: Adult; Blindness; Dexamethasone; Drug Combinations; Extravasation of Diagnostic and Therapeutic Mate

2009
Anesthesia following overfilling of a root canal sealer into the mandibular canal: a case report.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2006, Volume: 101, Issue:6

    Topics: Adult; Decompression, Surgical; Dexamethasone; Drug Combinations; Extravasation of Diagnostic and Th

2006
Patient in Sargenti case gets new trial.
    Journal of the American Dental Association (1939), 1992, Volume: 123, Issue:4

    Topics: Alabama; Drug Combinations; Eugenol; Extravasation of Diagnostic and Therapeutic Materials; Facial P

1992
Endomethasone root canal filling material in the mandibular canal. A case report.
    Oral surgery, oral medicine, and oral pathology, 1989, Volume: 68, Issue:3

    Topics: Administration, Topical; Adolescent; Anti-Inflammatory Agents; Dental Pulp; Dexamethasone; Drug Comb

1989
Painful dysesthesia of the inferior alveolar nerve following use of a paraformaldehyde-containing root canal sealer.
    Endodontics & dental traumatology, 1988, Volume: 4, Issue:1

    Topics: Drug Combinations; Eugenol; Female; Formaldehyde; Humans; Hypesthesia; Mandibular Nerve; Middle Aged

1988