Page last updated: 2024-10-18

formaldehyde and Hematologic Malignancies

formaldehyde has been researched along with Hematologic Malignancies in 15 studies

paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy

Research Excerpts

ExcerptRelevanceReference
"Recent scientific debate has focused on the potential for inhaled formaldehyde to cause lymphohematopoietic cancers, particularly leukemias, in humans."7.77Is exposure to formaldehyde in air causally associated with leukemia?--A hypothesis-based weight-of-evidence analysis. ( Bailey, LA; Goodman, JE; Hamade, AK; Mayfield, D; Rhomberg, LR, 2011)
" Apart from some isolated exceptions, relative risks were close to the null, and there was little evidence for dose-response relations for any of the LHM."6.48Critical review and synthesis of the epidemiologic evidence on formaldehyde exposure and risk of leukemia and other lymphohematopoietic malignancies. ( Boffetta, P; Checkoway, H; Mundt, DJ; Mundt, KA, 2012)
"Recent scientific debate has focused on the potential for inhaled formaldehyde to cause lymphohematopoietic cancers, particularly leukemias, in humans."3.77Is exposure to formaldehyde in air causally associated with leukemia?--A hypothesis-based weight-of-evidence analysis. ( Bailey, LA; Goodman, JE; Hamade, AK; Mayfield, D; Rhomberg, LR, 2011)
" Apart from some isolated exceptions, relative risks were close to the null, and there was little evidence for dose-response relations for any of the LHM."2.48Critical review and synthesis of the epidemiologic evidence on formaldehyde exposure and risk of leukemia and other lymphohematopoietic malignancies. ( Boffetta, P; Checkoway, H; Mundt, DJ; Mundt, KA, 2012)
"For brain cancer and lymphohematopoietic neoplasms there were modestly elevated risks in professionals, but not industry workers."2.44Formaldehyde and cancer risk: a quantitative review of cohort studies through 2006. ( Bosetti, C; La Vecchia, C; McLaughlin, JK; Pira, E; Tarone, RE, 2008)
"Acute myeloid leukemia was unrelated to cumulative exposure."1.42Formaldehyde Exposure and Mortality Risks From Acute Myeloid Leukemia and Other Lymphohematopoietic Malignancies in the US National Cancer Institute Cohort Study of Workers in Formaldehyde Industries. ( Boffetta, P; Checkoway, H; Crawford, L; Dell, LD; Gallagher, AE; Lees, PS; Mundt, KA, 2015)
"Excess mortality from lymphohematopoietic malignancies, in particular myeloid leukemia, and brain cancer has been found in surveys of anatomists, pathologists, and funeral industry workers, all of whom may have worked with formaldehyde."1.35Mortality from lymphohematopoietic malignancies and brain cancer among embalmers exposed to formaldehyde. ( Beane Freeman, LE; Blair, A; Fraumeni, JF; Hauptmann, M; Hayes, RB; Herrick, RF; Hoover, RN; Hornung, RW; Lubin, JH; Stewart, PA, 2009)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (46.67)29.6817
2010's8 (53.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Allegra, A1
Spatari, G1
Mattioli, S1
Curti, S1
Innao, V1
Ettari, R1
Allegra, AG1
Giorgianni, C1
Gangemi, S1
Musolino, C1
Checkoway, H2
Dell, LD1
Boffetta, P2
Gallagher, AE1
Crawford, L1
Lees, PS1
Mundt, KA2
Soffritti, M1
Tibaldi, E1
Padovani, M1
Hoel, DG1
Giuliani, L1
Bua, L1
Lauriola, M1
Falcioni, L1
Manservigi, M1
Manservisi, F1
Belpoggi, F1
Beane Freeman, LE2
Blair, A3
Lubin, JH3
Stewart, PA3
Hayes, RB3
Hoover, RN2
Hauptmann, M3
Hornung, RW1
Herrick, RF1
Fraumeni, JF1
Cole, P3
Adami, HO2
Trichopoulos, D2
Mandel, J1
Mandel, JS1
Hammer, N1
Löffler, S1
Feja, C1
Bechmann, I1
Steinke, H1
Rhomberg, LR1
Bailey, LA1
Goodman, JE1
Hamade, AK1
Mayfield, D1
Mundt, DJ1
Casanova, M1
Collins, JJ1
Conolly, R1
Delzell, E1
Heck Hd, Hd1
Leonard, R1
Lewis, R1
Marsh, GM1
Ott, MG1
Sorahan, T1
Axten, CW1
Korac, P1
Jones, M1
Dominis, M1
Kusec, R1
Mason, DY1
Banham, AH1
Ventura, RA1
Kunder, S1
Calzada-Wack, J1
Hölzlwimmer, G1
Müller, J1
Kloss, C1
Howat, W1
Schmidt, J1
Höfler, H1
Warren, M1
Quintanilla-Martinez, L1
Bosetti, C1
McLaughlin, JK1
Tarone, RE1
Pira, E1
La Vecchia, C1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Cross-Sectional Study of Hematotoxicity in Workers Exposed to Formaldehyde[NCT01547858]708 participants (Actual)Observational2012-02-09Completed
Studies of Myeloid Progenitor Cells in Workers Exposed to Formaldehyde, a Putative Leukemogen[NCT01338285]94 participants (Actual)Observational2006-06-10Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for formaldehyde and Hematologic Malignancies

ArticleYear
Formaldehyde Exposure and Acute Myeloid Leukemia: A Review of the Literature.
    Medicina (Kaunas, Lithuania), 2019, Sep-25, Volume: 55, Issue:10

    Topics: Formaldehyde; Hematologic Neoplasms; Humans; Leukemia, Myeloid, Acute; Occupational Diseases; Occupa

2019
Critical review and synthesis of the epidemiologic evidence on formaldehyde exposure and risk of leukemia and other lymphohematopoietic malignancies.
    Cancer causes & control : CCC, 2012, Volume: 23, Issue:11

    Topics: Case-Control Studies; Cohort Studies; Formaldehyde; Hematologic Neoplasms; Humans; Leukemia; Occupat

2012
Formaldehyde and cancer risk: a quantitative review of cohort studies through 2006.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19, Issue:1

    Topics: Air Pollutants, Occupational; Animals; Brain Neoplasms; Carcinogens, Environmental; Cohort Studies;

2008

Other Studies

12 other studies available for formaldehyde and Hematologic Malignancies

ArticleYear
Formaldehyde Exposure and Mortality Risks From Acute Myeloid Leukemia and Other Lymphohematopoietic Malignancies in the US National Cancer Institute Cohort Study of Workers in Formaldehyde Industries.
    Journal of occupational and environmental medicine, 2015, Volume: 57, Issue:7

    Topics: Adult; Cohort Studies; Female; Formaldehyde; Hematologic Neoplasms; Humans; Leukemia, Myeloid, Acute

2015
Synergism between sinusoidal-50 Hz magnetic field and formaldehyde in triggering carcinogenic effects in male Sprague-Dawley rats.
    American journal of industrial medicine, 2016, Volume: 59, Issue:7

    Topics: Animals; Carcinogens; Cocarcinogenesis; Female; Formaldehyde; Hematologic Neoplasms; Kaplan-Meier Es

2016
Mortality from lymphohematopoietic malignancies among workers in formaldehyde industries: the National Cancer Institute Cohort.
    Journal of the National Cancer Institute, 2009, May-20, Volume: 101, Issue:10

    Topics: Adult; Aged; Cohort Studies; Female; Follow-Up Studies; Formaldehyde; Hematologic Neoplasms; Humans;

2009
Mortality from lymphohematopoietic malignancies and brain cancer among embalmers exposed to formaldehyde.
    Journal of the National Cancer Institute, 2009, Dec-16, Volume: 101, Issue:24

    Topics: Aged; Aged, 80 and over; Brain Neoplasms; Female; Fixatives; Formaldehyde; Funeral Rites; Hematologi

2009
Formaldehyde and lymphohematopoietic cancers: a review of two recent studies.
    Regulatory toxicology and pharmacology : RTP, 2010, Volume: 58, Issue:2

    Topics: Disinfectants; Embalming; Epidemiologic Methods; Fixatives; Formaldehyde; Hematologic Neoplasms; Hum

2010
Re: Mortality from lymphohematopoietic malignancies and brain cancer among embalmers exposed to formaldehyde.
    Journal of the National Cancer Institute, 2010, Oct-06, Volume: 102, Issue:19

    Topics: Adult; Aged; Brain Neoplasms; Case-Control Studies; Fixatives; Formaldehyde; Hematologic Neoplasms;

2010
Substitution of formaldehyde in cross anatomy is possible.
    Journal of the National Cancer Institute, 2011, Apr-06, Volume: 103, Issue:7

    Topics: Anatomy; Cadaver; Carcinogens; Ethanol; Fixatives; Formaldehyde; Glycerol; Hematologic Neoplasms; Hu

2011
Is exposure to formaldehyde in air causally associated with leukemia?--A hypothesis-based weight-of-evidence analysis.
    Critical reviews in toxicology, 2011, Volume: 41, Issue:7

    Topics: Air Pollutants; Animals; Carcinogens, Environmental; Causality; Confounding Factors, Epidemiologic;

2011
Mortality from lymphohematopoietic malignancies among workers in formaldehyde industries.
    Journal of the National Cancer Institute, 2003, Nov-05, Volume: 95, Issue:21

    Topics: Adult; Aged; Carcinogens; Chemical Industry; Cohort Studies; Disinfectants; Fixatives; Formaldehyde;

2003
Re: Mortality from lymphohematopoietic malignancies among workers in formaldehyde industries.
    Journal of the National Cancer Institute, 2004, Jun-16, Volume: 96, Issue:12

    Topics: Carcinogens; Chemical Industry; Disinfectants; Fixatives; Formaldehyde; Hematologic Neoplasms; Human

2004
Application of the FICTION technique for the simultaneous detection of immunophenotype and chromosomal abnormalities in routinely fixed, paraffin wax embedded bone marrow trephines.
    Journal of clinical pathology, 2005, Volume: 58, Issue:12

    Topics: Antigens, CD20; Antigens, Neoplasm; Biopsy; Bone Marrow Examination; Chromosome Aberrations; Edetic

2005
A comprehensive antibody panel for immunohistochemical analysis of formalin-fixed, paraffin-embedded hematopoietic neoplasms of mice: analysis of mouse specific and human antibodies cross-reactive with murine tissue.
    Toxicologic pathology, 2007, Volume: 35, Issue:3

    Topics: Aging; Animals; Antibodies; Cross Reactions; Female; Fixatives; Formaldehyde; Hematologic Neoplasms;

2007