Page last updated: 2024-10-18

formaldehyde and Glioma

formaldehyde has been researched along with Glioma in 29 studies

paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"Using DAPI-DNA cytofluorometry, the author analyzed nuclear DNA content of formalin fixed, paraffin embedded, glioma material obtained from 14 glioma cases at surgery."7.68[DAPI-DNA cytofluorometric study of glioma cells--application of DAPI-DNA cytofluorometry to paraffin embedded archival glioma tissue for nuclear DNA content analysis]. ( Nagashima, R, 1990)
"Using DAPI-DNA cytofluorometry, the author analyzed nuclear DNA content of formalin fixed, paraffin embedded, glioma material obtained from 14 glioma cases at surgery."3.68[DAPI-DNA cytofluorometric study of glioma cells--application of DAPI-DNA cytofluorometry to paraffin embedded archival glioma tissue for nuclear DNA content analysis]. ( Nagashima, R, 1990)
"Oligodendroglioma is a glioma subtype characterized by 1p/19q co-deletion and IDH1/IDH2 mutations, which predict a good prognosis, responsiveness to therapy, and an improved overall survival compared to other adult gliomas."1.72Utility of targeted next-generation sequencing assay to detect 1p/19q co-deletion in formalin-fixed paraffin-embedded glioma specimens. ( Adams, E; Eshleman, JR; Gocke, CD; Haley, L; Hardy, M; Huang, J; Long, P; Morsberger, L; Pallavajjala, A; Pallavajjala, R; Rodriguez, FJ; Stinnett, V; Zou, YS, 2022)
"Gliomas were analyzed for MGMT methylation, glioma CpG island methylator phenotype and IDH1 R132H."1.43MethylMeter(®): bisulfite-free quantitative and sensitive DNA methylation profiling and mutation detection in FFPE samples. ( Diago, OR; Hanna, MM; Hogan, DJ; McCarthy, D; Ostertag, D; Pulverer, W; Weinhaeusel, A, 2016)
"Because diffuse malignant gliomas are often sampled by small biopsies, formalin-fixed paraffin-embedded (FFPE) blocks are often the only tissue available for genetic analysis; FFPE tissues are also needed to study the intratumoral heterogeneity that characterizes these neoplasms."1.37Genome-wide comparison of paired fresh frozen and formalin-fixed paraffin-embedded gliomas by custom BAC and oligonucleotide array comparative genomic hybridization: facilitating analysis of archival gliomas. ( Batchelor, TT; Bernay, DC; Betensky, RA; Engler, DA; Kim, JC; Louis, DN; Mohapatra, G; Rousseau, A; Scangas, GA; Starbuck, KD, 2011)
"They frequently are found in pilocytic astrocytomas, where genomic duplications involving BRAF and the poorly characterized gene KIAA1549 create fusion proteins with constitutive B-Raf kinase activity."1.37Detection of KIAA1549-BRAF fusion transcripts in formalin-fixed paraffin-embedded pediatric low-grade gliomas. ( Chan, JA; Craig, JM; Garraway, LA; Goldman, S; Kieran, MW; Ligon, AH; Ligon, KL; Lindeman, NI; Longtine, JA; Macconaill, LE; Mahmoud, M; Ozek, M; Rajaram, V; Rich, BE; Santagata, S; Sav, A; Stiles, CD; Taha, H; Tian, Y; Vena, N, 2011)
"In cohorts of ovarian cancers and gliomas, MET4 reacted with ovarian cancers of all histologic subtypes (strong staining in 25%) and with 63% of gliomas."1.35A novel multipurpose monoclonal antibody for evaluating human c-Met expression in preclinical and clinical settings. ( Berghuis, B; Cao, B; Cottingham, S; Daugherty, J; Gherardi, E; Giambernardi, T; Grabinski, T; Gross, M; Hay, R; Hudson, E; Knudsen, BS; Kort, E; Lengyel, E; Resau, J; Skinner, RS; Toro, J; Vande Woude, G; Ventura, A; West, RA; Xie, Q; Xu, E; Zhao, P, 2009)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.45)18.7374
1990's5 (17.24)18.2507
2000's7 (24.14)29.6817
2010's12 (41.38)24.3611
2020's4 (13.79)2.80

Authors

AuthorsStudies
Ishikawa, E1
Tsuboi, K1
Takano, S1
Uchimura, E1
Nose, T1
Ohno, T1
Pellicciari, C1
Mangiarotti, R1
Bottone, MG1
Danova, M1
Wang, E1
Pallavajjala, A1
Haley, L1
Stinnett, V1
Adams, E1
Pallavajjala, R1
Huang, J1
Morsberger, L1
Hardy, M1
Long, P1
Gocke, CD2
Eshleman, JR2
Rodriguez, FJ1
Zou, YS1
Nelson, EJ1
Gubbiotti, MA1
Carlin, AM1
Nasrallah, MP1
Van Deerlin, VM1
Herlihy, SE1
Gul, SI1
Ayoub, A1
Ali, SA1
Hanook, S1
Baig, DN1
Alenda, C1
Rojas, E1
Valor, LM1
Movassaghi, M1
Shabihkhani, M1
Hojat, SA1
Williams, RR1
Chung, LK1
Im, K1
Lucey, GM1
Wei, B1
Mareninov, S1
Wang, MW1
Ng, DW1
Tashjian, RS1
Magaki, S1
Perez-Rosendahl, M1
Yang, I1
Khanlou, N1
Vinters, HV1
Liau, LM1
Nghiemphu, PL1
Lai, A1
Cloughesy, TF1
Yong, WH1
Forest, F1
Cinotti, E1
Yvorel, V1
Habougit, C1
Vassal, F1
Nuti, C1
Perrot, JL1
Labeille, B1
Péoc'h, M1
McCarthy, D1
Pulverer, W1
Weinhaeusel, A1
Diago, OR1
Hogan, DJ1
Ostertag, D1
Hanna, MM1
Kossatz, S1
Carney, B1
Schweitzer, M1
Carlucci, G1
Miloushev, VZ1
Maachani, UB1
Rajappa, P1
Keshari, KR1
Pisapia, D1
Weber, WA1
Souweidane, MM1
Reiner, T1
Knudsen, BS1
Zhao, P1
Resau, J1
Cottingham, S1
Gherardi, E1
Xu, E1
Berghuis, B1
Daugherty, J1
Grabinski, T1
Toro, J1
Giambernardi, T1
Skinner, RS1
Gross, M1
Hudson, E1
Kort, E1
Lengyel, E1
Ventura, A1
West, RA1
Xie, Q1
Hay, R1
Vande Woude, G1
Cao, B1
Horbinski, C1
Kofler, J1
Kelly, LM1
Murdoch, GH1
Nikiforova, MN1
Wiwanitkit, V1
Mohapatra, G2
Engler, DA2
Starbuck, KD1
Kim, JC1
Bernay, DC1
Scangas, GA1
Rousseau, A1
Batchelor, TT1
Betensky, RA2
Louis, DN2
Sahm, F1
Capper, D2
Pusch, S1
Balss, J1
Koch, A1
Langhans, CD1
Okun, JG1
von Deimling, A2
Harada, S1
Henderson, LB1
Burger, P1
Griffin, CA1
Batista, DA1
Tian, Y1
Rich, BE1
Vena, N1
Craig, JM1
Macconaill, LE1
Rajaram, V1
Goldman, S1
Taha, H1
Mahmoud, M1
Ozek, M1
Sav, A1
Longtine, JA1
Lindeman, NI1
Garraway, LA1
Ligon, AH1
Stiles, CD1
Santagata, S1
Chan, JA2
Kieran, MW1
Ligon, KL1
Gravendeel, LA1
de Rooi, JJ1
Eilers, PH1
van den Bent, MJ1
Sillevis Smitt, PA1
French, PJ1
Perizzolo, M1
Winkfein, B1
Hui, S1
Krulicki, W1
Demetrick, DJ1
Lass, U1
Hartmann, C1
Herold-Mende, C1
Meiboom, M1
Mueller, W1
Hunter, SB2
Varma, V1
Shehata, B1
Nolen, JD1
Cohen, C1
Olson, JJ2
Ou, CY1
Ali, MJ1
Navalitloha, Y1
Vavra, MW1
Kang, EW1
Itskovich, AC1
Molnar, P1
Levy, RM1
Groothuis, DR1
Miller, ER1
Carey, B1
Gaumont, LD1
Schiltz, PM1
Lee, GJ1
Zhang, JG1
Hoa, N1
Wepsic, HT1
Dillman, RO1
Jadus, MR1
Hoyt, JW1
Gown, AM1
Kim, DK1
Berger, MS1
Abbott, K1
Varma, VA1
Barnett, DW1
James, CD1
Nagashima, R1
Shin, RW1
Iwaki, T1
Kitamoto, T1
Tateishi, J1
Thaw, HH1

Other Studies

29 other studies available for formaldehyde and Glioma

ArticleYear
Intratumoral injection of IL-2-activated NK cells enhances the antitumor effect of intradermally injected paraformaldehyde-fixed tumor vaccine in a rat intracranial brain tumor model.
    Cancer science, 2004, Volume: 95, Issue:1

    Topics: Animals; Brain Neoplasms; Cancer Vaccines; Cytotoxicity Tests, Immunologic; Disease Models, Animal;

2004
Identification of resting cells by dual-parameter flow cytometry of statin expression and DNA content.
    Cytometry, 1995, Dec-01, Volume: 21, Issue:4

    Topics: 3T3 Cells; Animals; Antigens, Neoplasm; Apoptosis; Biomarkers; Breast Neoplasms; Bromodeoxyuridine;

1995
Utility of targeted next-generation sequencing assay to detect 1p/19q co-deletion in formalin-fixed paraffin-embedded glioma specimens.
    Human pathology, 2022, Volume: 126

    Topics: Brain Neoplasms; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 1; Chromosome

2022
Clinical Evaluation of IDH Mutation Status in Formalin-Fixed Paraffin-Embedded Tissue in Gliomas.
    Molecular diagnosis & therapy, 2023, Volume: 27, Issue:3

    Topics: Brain Neoplasms; Formaldehyde; Glioma; Humans; Isocitrate Dehydrogenase; Mutation; Paraffin Embeddin

2023
Profilin 3 genetic architecture in glioma formalin fixed paraffin embedded (FFPE) archive.
    Gene, 2021, Jun-30, Volume: 787

    Topics: Brain Neoplasms; Formaldehyde; Gene Expression Regulation, Neoplastic; Glioma; Humans; Paraffin Embe

2021
FFPE samples from cavitational ultrasonic surgical aspirates are suitable for RNA profiling of gliomas.
    PloS one, 2021, Volume: 16, Issue:7

    Topics: Formaldehyde; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Humans; Par

2021
Early experience with formalin-fixed paraffin-embedded (FFPE) based commercial clinical genomic profiling of gliomas-robust and informative with caveats.
    Experimental and molecular pathology, 2017, Volume: 103, Issue:1

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Class I Phosphatidylinositol 3-Kinases; ErbB Receptors; Fe

2017
Ex vivo confocal microscopy imaging to identify tumor tissue on freshly removed brain sample.
    Journal of neuro-oncology, 2015, Volume: 124, Issue:2

    Topics: Brain; Brain Neoplasms; Carcinoma; Cryopreservation; Formaldehyde; Glioma; Humans; Meningioma; Micro

2015
MethylMeter(®): bisulfite-free quantitative and sensitive DNA methylation profiling and mutation detection in FFPE samples.
    Epigenomics, 2016, Volume: 8, Issue:6

    Topics: Brain Neoplasms; CpG Islands; DNA Copy Number Variations; DNA Methylation; DNA Modification Methylas

2016
Biomarker-Based PET Imaging of Diffuse Intrinsic Pontine Glioma in Mouse Models.
    Cancer research, 2017, 04-15, Volume: 77, Issue:8

    Topics: Animals; Biomarkers, Tumor; Brain Stem Neoplasms; Chickens; Disease Models, Animal; Formaldehyde; Gl

2017
A novel multipurpose monoclonal antibody for evaluating human c-Met expression in preclinical and clinical settings.
    Applied immunohistochemistry & molecular morphology : AIMM, 2009, Volume: 17, Issue:1

    Topics: Antibodies, Monoclonal; Biomarkers, Tumor; Female; Formaldehyde; Glioma; Humans; Immunohistochemistr

2009
Diagnostic use of IDH1/2 mutation analysis in routine clinical testing of formalin-fixed, paraffin-embedded glioma tissues.
    Journal of neuropathology and experimental neurology, 2009, Volume: 68, Issue:12

    Topics: Biomarkers, Tumor; Brain Neoplasms; DNA Mutational Analysis; Formaldehyde; Glioma; Humans; Isocitrat

2009
Correspondence regarding: diagnostic utility of IDH1/2 mutation analysis in routine clinical testing of formalin-fixed paraffin-embedded glioma tissues. J Neuropathol Exp Neurol 2009:68;1319-25.
    Journal of neuropathology and experimental neurology, 2010, Volume: 69, Issue:3

    Topics: Biomarkers, Tumor; Brain Neoplasms; Cost-Benefit Analysis; Diagnosis, Differential; DNA Mutational A

2010
Genome-wide comparison of paired fresh frozen and formalin-fixed paraffin-embedded gliomas by custom BAC and oligonucleotide array comparative genomic hybridization: facilitating analysis of archival gliomas.
    Acta neuropathologica, 2011, Volume: 121, Issue:4

    Topics: Cell Line, Tumor; Chromosomes, Artificial, Bacterial; Comparative Genomic Hybridization; Fixatives;

2011
Detection of 2-hydroxyglutarate in formalin-fixed paraffin-embedded glioma specimens by gas chromatography/mass spectrometry.
    Brain pathology (Zurich, Switzerland), 2012, Volume: 22, Issue:1

    Topics: Brain Neoplasms; Fixatives; Formaldehyde; Gas Chromatography-Mass Spectrometry; Glioma; Glutarates;

2012
Genomic changes in gliomas detected using single nucleotide polymorphism array in formalin-fixed, paraffin-embedded tissue: superior results compared with microsatellite analysis.
    The Journal of molecular diagnostics : JMD, 2011, Volume: 13, Issue:5

    Topics: Adult; Brain Neoplasms; Chromosomes, Human; DNA, Neoplasm; Female; Formaldehyde; Genome, Human; Glio

2011
Detection of KIAA1549-BRAF fusion transcripts in formalin-fixed paraffin-embedded pediatric low-grade gliomas.
    The Journal of molecular diagnostics : JMD, 2011, Volume: 13, Issue:6

    Topics: Adolescent; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Child; Child, Preschool; Comparative Ge

2011
Gene expression profiles of gliomas in formalin-fixed paraffin-embedded material.
    British journal of cancer, 2012, Jan-31, Volume: 106, Issue:3

    Topics: Brain Neoplasms; Cluster Analysis; Fixatives; Formaldehyde; Frozen Sections; Gene Expression Profili

2012
IDH mutation detection in formalin-fixed paraffin-embedded gliomas using multiplex PCR and single-base extension.
    Brain pathology (Zurich, Switzerland), 2012, Volume: 22, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Female; Formaldehyde; Glioma; Humans; I

2012
Chromogenic in situ hybridization is a reliable alternative to fluorescence in situ hybridization for diagnostic testing of 1p and 19q loss in paraffin-embedded gliomas.
    Brain pathology (Zurich, Switzerland), 2013, Volume: 23, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chromosome Deletion; Chromosomes, Human

2013
Apolipoprotein D expression in primary brain tumors: analysis by quantitative RT-PCR in formalin-fixed, paraffin-embedded tissue.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2005, Volume: 53, Issue:8

    Topics: Apolipoproteins; Apolipoproteins D; Brain Neoplasms; Cell Proliferation; Fixatives; Formaldehyde; Gl

2005
Isolation of drug delivery from drug effect: problems of optimizing drug delivery parameters.
    Neuro-oncology, 2006, Volume: 8, Issue:2

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Drug Adminis

2006
Glioma test array for use with formalin-fixed, paraffin-embedded tissue: array comparative genomic hybridization correlates with loss of heterozygosity and fluorescence in situ hybridization.
    The Journal of molecular diagnostics : JMD, 2006, Volume: 8, Issue:2

    Topics: Cold Temperature; DNA; Female; Formaldehyde; Genome; Glioma; Humans; In Situ Hybridization, Fluoresc

2006
Human allogeneic and murine xenogeneic dendritic cells are cytotoxic to human tumor cells via two distinct pathways.
    Cancer biotherapy & radiopharmaceuticals, 2007, Volume: 22, Issue:5

    Topics: Alstrom Syndrome; Animals; Apoptosis; Caco-2 Cells; Caspase 8; Cell Line, Transformed; Cell Line, Tu

2007
Analysis of proliferative grade in glial neoplasms using antibodies to the Ki-67 defined antigen and PCNA in formalin fixed, deparaffinized tissues.
    Journal of neuro-oncology, 1995, Volume: 24, Issue:2

    Topics: Antibodies, Monoclonal; Biomarkers, Tumor; Brain Neoplasms; Cell Cycle; Cell Division; Fixatives; Fl

1995
Reliability of differential PCR for the detection of EGFR and MDM2 gene amplification in DNA extracted from FFPE glioma tissue.
    Journal of neuropathology and experimental neurology, 1995, Volume: 54, Issue:1

    Topics: Adult; Aged; Base Sequence; DNA, Neoplasm; ErbB Receptors; Evaluation Studies as Topic; Female; Fixa

1995
[DAPI-DNA cytofluorometric study of glioma cells--application of DAPI-DNA cytofluorometry to paraffin embedded archival glioma tissue for nuclear DNA content analysis].
    No to shinkei = Brain and nerve, 1990, Volume: 42, Issue:4

    Topics: Adult; Aged; Brain Neoplasms; Cell Nucleus; Child, Preschool; Cytophotometry; DNA, Neoplasm; Female;

1990
Hydrated autoclave pretreatment enhances tau immunoreactivity in formalin-fixed normal and Alzheimer's disease brain tissues.
    Laboratory investigation; a journal of technical methods and pathology, 1991, Volume: 64, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Brain; Cell Line; Formaldehyde; Glioma; Humans; I

1991
Optimal conditions for the measurement of lipid peroxidation products (lipofuscin) in individual cultivated human glial and glioma cells.
    Mechanisms of ageing and development, 1987, Volume: 38, Issue:1

    Topics: Acetates; Acetic Acid; Cell Line; Ethanol; Fluorometry; Formaldehyde; Glioma; Glycerol; Humans; Lipo

1987