formaldehyde has been researched along with Genome Instability in 11 studies
paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy
| Excerpt | Relevance | Reference |
|---|---|---|
| "Formaldehyde is a reactive chemical that is commonly used in the production of industrial, laboratory, household, and cosmetic products." | 5.38 | Formaldehyde-induced genome instability is suppressed by an XPF-dependent pathway. ( Kumari, A; Lim, YX; McCullough, AK; Newell, AH; Olson, SB, 2012) |
| "FANCD2 is required for the repair of DNA damage by the FA (Fanconi anemia) pathway, and, consequently, FANCD2-deficient cells are sensitive to compounds such as cisplatin and formaldehyde that induce DNA:DNA and DNA:protein crosslinks, respectively." | 3.80 | Preventing over-resection by DNA2 helicase/nuclease suppresses repair defects in Fanconi anemia cells. ( Campbell, JL; Hendrickson, EA; Karanja, KK; Lee, EH, 2014) |
| "Fanconi Anemia (FA) is a rare, genome instability-associated disease characterized by a deficiency in repairing DNA crosslinks, which are known to perturb several cellular processes, including DNA transcription, replication, and repair." | 1.91 | A CRISPR-Cas9 screen identifies EXO1 as a formaldehyde resistance gene. ( Blondeau, A; Coulombe, Y; Dessapt, J; Duxin, JP; Fradet-Turcotte, A; Gao, Y; Guitton-Sert, L; Hussein, S; Larsen, NB; Masson, JY; Milano, L; Rodrigue, A, 2023) |
| "Formaldehyde is a reactive aldehyde that has been classified as a class I human carcinogen by the International Agency for Cancer Research." | 1.42 | BLM protein mitigates formaldehyde-induced genomic instability. ( Juarez, E; Kumari, A; McCullough, AK; Owen, N, 2015) |
| "Formaldehyde is a reactive chemical that is commonly used in the production of industrial, laboratory, household, and cosmetic products." | 1.38 | Formaldehyde-induced genome instability is suppressed by an XPF-dependent pathway. ( Kumari, A; Lim, YX; McCullough, AK; Newell, AH; Olson, SB, 2012) |
| "The three studies evaluated untreated cancer patients, welders, and pathologists/anatomists exposed to formaldehyde." | 1.34 | Exposure to genotoxic agents, host factors, and lifestyle influence the number of centromeric signals in micronuclei: a pooled re-analysis. ( Baciuchka-Palmaro, M; Bonassi, S; Botta, A; Iarmarcovai, G; Orsière, T; Sari-Minodier, I, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Fumagalli, C | 1 |
| Betella, I | 1 |
| Ranghiero, A | 1 |
| Guerini-Rocco, E | 1 |
| Bonaldo, G | 1 |
| Rappa, A | 1 |
| Vacirca, D | 1 |
| Colombo, N | 1 |
| Barberis, M | 1 |
| Gao, Y | 1 |
| Guitton-Sert, L | 1 |
| Dessapt, J | 1 |
| Coulombe, Y | 1 |
| Rodrigue, A | 1 |
| Milano, L | 1 |
| Blondeau, A | 1 |
| Larsen, NB | 1 |
| Duxin, JP | 1 |
| Hussein, S | 1 |
| Fradet-Turcotte, A | 1 |
| Masson, JY | 1 |
| Shen, X | 1 |
| Wang, R | 1 |
| Kim, MJ | 1 |
| Hu, Q | 1 |
| Hsu, CC | 1 |
| Yao, J | 1 |
| Klages-Mundt, N | 1 |
| Tian, Y | 1 |
| Lynn, E | 1 |
| Brewer, TF | 1 |
| Zhang, Y | 1 |
| Arun, B | 1 |
| Gan, B | 1 |
| Andreeff, M | 1 |
| Takeda, S | 1 |
| Chen, J | 1 |
| Park, JI | 1 |
| Shi, X | 1 |
| Chang, CJ | 1 |
| Jung, SY | 1 |
| Qin, J | 1 |
| Li, L | 1 |
| Tan, SLW | 1 |
| Chadha, S | 1 |
| Liu, Y | 1 |
| Gabasova, E | 1 |
| Perera, D | 1 |
| Ahmed, K | 1 |
| Constantinou, S | 1 |
| Renaudin, X | 1 |
| Lee, M | 1 |
| Aebersold, R | 1 |
| Venkitaraman, AR | 1 |
| Kamieniak, MM | 1 |
| Muñoz-Repeto, I | 1 |
| Rico, D | 1 |
| Osorio, A | 1 |
| Urioste, M | 1 |
| García-Donas, J | 1 |
| Hernando, S | 1 |
| Robles-Díaz, L | 1 |
| Ramón Y Cajal, T | 1 |
| Cazorla, A | 1 |
| Sáez, R | 1 |
| García-Bueno, JM | 1 |
| Domingo, S | 1 |
| Borrego, S | 1 |
| Palacios, J | 1 |
| van de Wiel, MA | 1 |
| Ylstra, B | 1 |
| Benítez, J | 1 |
| García, MJ | 1 |
| Karanja, KK | 1 |
| Lee, EH | 1 |
| Hendrickson, EA | 1 |
| Campbell, JL | 1 |
| Kumari, A | 2 |
| Owen, N | 1 |
| Juarez, E | 1 |
| McCullough, AK | 2 |
| Vaz, B | 1 |
| Popovic, M | 1 |
| Newman, JA | 1 |
| Fielden, J | 1 |
| Aitkenhead, H | 1 |
| Halder, S | 1 |
| Singh, AN | 1 |
| Vendrell, I | 1 |
| Fischer, R | 1 |
| Torrecilla, I | 1 |
| Drobnitzky, N | 1 |
| Freire, R | 1 |
| Amor, DJ | 1 |
| Lockhart, PJ | 1 |
| Kessler, BM | 1 |
| McKenna, GW | 1 |
| Gileadi, O | 1 |
| Ramadan, K | 1 |
| Lim, YX | 1 |
| Newell, AH | 1 |
| Olson, SB | 1 |
| Nessling, M | 1 |
| Richter, K | 1 |
| Schwaenen, C | 1 |
| Roerig, P | 1 |
| Wrobel, G | 1 |
| Wessendorf, S | 1 |
| Fritz, B | 1 |
| Bentz, M | 1 |
| Sinn, HP | 1 |
| Radlwimmer, B | 1 |
| Lichter, P | 1 |
| Iarmarcovai, G | 1 |
| Bonassi, S | 1 |
| Sari-Minodier, I | 1 |
| Baciuchka-Palmaro, M | 1 |
| Botta, A | 1 |
| Orsière, T | 1 |
11 other studies available for formaldehyde and Genome Instability
| Article | Year |
|---|---|
In-house testing for homologous recombination repair deficiency (HRD) testing in ovarian carcinoma: a feasibility study comparing AmoyDx HRD Focus panel with Myriad myChoiceCDx assay.
Topics: Adenosine Diphosphate Ribose; BRCA1 Protein; BRCA2 Protein; Carcinoma, Ovarian Epithelial; Feasibili | 2022 |
A CRISPR-Cas9 screen identifies EXO1 as a formaldehyde resistance gene.
Topics: CRISPR-Cas Systems; DNA; DNA Damage; DNA Repair; DNA Repair Enzymes; DNA Replication; Drug Tolerance | 2023 |
A Surge of DNA Damage Links Transcriptional Reprogramming and Hematopoietic Deficit in Fanconi Anemia.
Topics: Cell Differentiation; Cellular Reprogramming; DNA Damage; DNA Repair; Fanconi Anemia; Formaldehyde; | 2020 |
A Class of Environmental and Endogenous Toxins Induces BRCA2 Haploinsufficiency and Genome Instability.
Topics: BRCA2 Protein; Chromosome Aberrations; DNA Damage; DNA Replication; DNA-Binding Proteins; Formaldehy | 2017 |
DNA copy number profiling reveals extensive genomic loss in hereditary BRCA1 and BRCA2 ovarian carcinomas.
Topics: Carcinoma, Ovarian Epithelial; Comparative Genomic Hybridization; DNA Copy Number Variations; DNA, N | 2013 |
Preventing over-resection by DNA2 helicase/nuclease suppresses repair defects in Fanconi anemia cells.
Topics: Cell Line, Tumor; Cisplatin; DNA Breaks, Double-Stranded; DNA Helicases; DNA Repair; Fanconi Anemia; | 2014 |
BLM protein mitigates formaldehyde-induced genomic instability.
Topics: Ataxia Telangiectasia Mutated Proteins; Cell Cycle Checkpoints; DNA; DNA Breaks, Double-Stranded; DN | 2015 |
Metalloprotease SPRTN/DVC1 Orchestrates Replication-Coupled DNA-Protein Crosslink Repair.
Topics: Amino Acid Sequence; Binding Sites; Cross-Linking Reagents; DNA; DNA Damage; DNA Repair; DNA Replica | 2016 |
Formaldehyde-induced genome instability is suppressed by an XPF-dependent pathway.
Topics: Animals; Cell Death; Cell Nucleus; Centrosome; CHO Cells; Chromosome Breakage; Cricetinae; Cricetulu | 2012 |
Candidate genes in breast cancer revealed by microarray-based comparative genomic hybridization of archived tissue.
Topics: Breast Neoplasms; Chromosome Aberrations; Female; Formaldehyde; Genomic Instability; Humans; Nucleic | 2005 |
Exposure to genotoxic agents, host factors, and lifestyle influence the number of centromeric signals in micronuclei: a pooled re-analysis.
Topics: Case-Control Studies; Centromere; Environmental Monitoring; Female; Formaldehyde; Genomic Instabilit | 2007 |