formaldehyde has been researched along with Down Syndrome in 2 studies
paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy
Down Syndrome: A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hultén, MA | 1 |
| Old, RW | 1 |
| Martínez-Cué, C | 1 |
| Baamonde, C | 1 |
| Lumbreras, MA | 1 |
| Vallina, IF | 1 |
| Dierssen, M | 1 |
| Flórez, J | 1 |
2 other studies available for formaldehyde and Down Syndrome
| Article | Year |
|---|---|
Non-invasive prenatal diagnosis of Down's syndrome.
Topics: Down Syndrome; Fixatives; Formaldehyde; Humans; Polymorphism, Single Nucleotide; Prenatal Diagnosis | 2007 |
A murine model for Down syndrome shows reduced responsiveness to pain.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Down Syndrome; Escape Reaction; Formaldehyde; Hot | 1999 |