Page last updated: 2024-10-18

formaldehyde and Creutzfeldt-Jakob Syndrome

formaldehyde has been researched along with Creutzfeldt-Jakob Syndrome in 14 studies

paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy

Creutzfeldt-Jakob Syndrome: A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances, personality changes, ATAXIA; APHASIA, visual loss, weakness, muscle atrophy, MYOCLONUS, progressive dementia, and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY, BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS. (From N Engl J Med, 1998 Dec 31;339(27))

Research Excerpts

ExcerptRelevanceReference
"Materials commonly employed in the preparation of otologic homografts such as ethanol and formaldehyde are effective in vitro in inactivating human immunodeficiency virus (HIV)."3.67Can acquired immunodeficiency syndrome and Creutzfeldt-Jakob disease be transmitted via otologic homografts? ( Glasscock, ME; Jackson, CG; Knox, GW, 1988)
"The abnormal prion protein that causes prion diseases is resistant to formaldehyde and cannot be inactivated by all methods of cadaver fixation presently in use."2.82The risk of Creutzfeldt-Jakob disease infection in cadaveric surgical training. ( Endo, D; Murai, K; Ogami-Takamura, K; Saiki, K; Tsurumoto, T, 2022)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19908 (57.14)18.7374
1990's3 (21.43)18.2507
2000's2 (14.29)29.6817
2010's0 (0.00)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Ogami-Takamura, K1
Saiki, K1
Endo, D1
Murai, K1
Tsurumoto, T1
Kingsbury, DT1
Smeltzer, DA1
Amyx, HL2
Gibbs, CJ5
Gajdusek, DC6
Asher, DM1
Kobrine, A1
Sulima, MP1
Privat, N1
Sazdovitch, V1
Seilhean, D1
LaPlanche, JL1
Hauw, JJ1
Van Everbroeck, B1
Croes, EA1
Pals, P1
Dermaut, B1
Jansen, G1
van Duijn, CM1
Cruts, M1
Van Broeckhoven, C1
Martin, JJ1
Cras, P1
Bernoulli, C1
Siegfried, J1
Baumgartner, G1
Regli, F1
Rabinowicz, T1
Brown, P2
Wolff, A1
Mackenzie, JM1
Fellowes, W1
Taylor, DM2
McConnell, I1
Brumback, RA1
Glasscock, ME1
Jackson, CG1
Knox, GW1
Cathala, F1
LaBauge, R1

Reviews

1 review available for formaldehyde and Creutzfeldt-Jakob Syndrome

ArticleYear
The risk of Creutzfeldt-Jakob disease infection in cadaveric surgical training.
    Anatomical science international, 2022, Volume: 97, Issue:3

    Topics: Cadaver; Creutzfeldt-Jakob Syndrome; Embalming; Formaldehyde; Humans; Prion Diseases

2022

Other Studies

13 other studies available for formaldehyde and Creutzfeldt-Jakob Syndrome

ArticleYear
Evidence for an unconventional virus in mouse-adapted Creutzfeldt-Jakob disease.
    Infection and immunity, 1982, Volume: 37, Issue:3

    Topics: Animals; Brain; Cell Line; Creutzfeldt-Jakob Syndrome; Cytopathogenic Effect, Viral; Detergents; For

1982
Transmission of Creutzfeldt-Jakob disease to a chimpanzee by electrodes contaminated during neurosurgery.
    Journal of neurology, neurosurgery, and psychiatry, 1994, Volume: 57, Issue:6

    Topics: Animals; Creutzfeldt-Jakob Syndrome; Electrodes, Implanted; Equipment Contamination; Equipment Reuse

1994
PrP immunohistochemistry: different protocols, including a procedure for long formalin fixation, and a proposed schematic classification for deposits in sporadic Creutzfeldt-Jakob disease.
    Microscopy research and technique, 2000, Jul-01, Volume: 50, Issue:1

    Topics: Brain; Creutzfeldt-Jakob Syndrome; Endopeptidase K; Fixatives; Formaldehyde; Humans; Immunohistochem

2000
Influence of the prion protein and the apolipoprotein E genotype on the Creutzfeldt-Jakob Disease phenotype.
    Neuroscience letters, 2001, Nov-02, Volume: 313, Issue:1-2

    Topics: Aged; Apolipoprotein E4; Apolipoproteins E; Creutzfeldt-Jakob Syndrome; Female; Fixatives; Formaldeh

2001
Danger of accidental person-to-person transmission of Creutzfeldt-Jakob disease by surgery.
    Lancet (London, England), 1977, Feb-26, Volume: 1, Issue:8009

    Topics: Adolescent; Adult; Aged; Animals; Brain; Creutzfeldt-Jakob Syndrome; Drug Resistance, Microbial; Ele

1977
Letter: Survival of Creutzfeldt-Jakob-disease virus in formol-fixed brain tissue.
    The New England journal of medicine, 1976, Mar-04, Volume: 294, Issue:10

    Topics: Animals; Brain; Creutzfeldt-Jakob Syndrome; Female; Formaldehyde; Histological Techniques; Humans; P

1976
A simple and effective method for inactivating virus infectivity in formalin-fixed tissue samples from patients with Creutzfeldt-Jakob disease.
    Neurology, 1990, Volume: 40, Issue:6

    Topics: Animals; Brain; Creutzfeldt-Jakob Syndrome; Cricetinae; Fixatives; Formaldehyde; Formates; Histologi

1990
Phenolized formalin fixation may obscure early histological changes of Creutzfeldt-Jakob disease.
    Neuropathology and applied neurobiology, 1990, Volume: 16, Issue:3

    Topics: Creutzfeldt-Jakob Syndrome; Fixatives; Formaldehyde; Histological Techniques; Humans; Phenol; Phenol

1990
Autoclaving does not decontaminate formol-fixed scrapie tissues.
    Lancet (London, England), 1988, Jun-25, Volume: 1, Issue:8600

    Topics: Animals; Brain; Creutzfeldt-Jakob Syndrome; Formaldehyde; Mice; Prions; Staining and Labeling; Steri

1988
Routine use of phenolized formalin in fixation of autopsy brain tissue to reduce risk of inadvertent transmission of Creutzfeldt-Jakob disease.
    The New England journal of medicine, 1988, Sep-08, Volume: 319, Issue:10

    Topics: Autopsy; Brain; Creutzfeldt-Jakob Syndrome; Fixatives; Formaldehyde; Humans; Laboratory Infection

1988
Can acquired immunodeficiency syndrome and Creutzfeldt-Jakob disease be transmitted via otologic homografts?
    Archives of otolaryngology--head & neck surgery, 1988, Volume: 114, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Creutzfeldt-Jakob Syndrome; Disinfection; Ear Ossicles; Ethanol;

1988
Decontamination of formaldehyde-fixed tissues of Creutzfeldt-Jakob disease.
    Journal of neuropathology and experimental neurology, 1986, Volume: 45, Issue:6

    Topics: Creutzfeldt-Jakob Syndrome; Decontamination; Fixatives; Formaldehyde; Humans

1986
Transmission of Creutzfeldt-Jakob disease from formalin-fixed, paraffin-embedded human brain tissue.
    The New England journal of medicine, 1986, Dec-18, Volume: 315, Issue:25

    Topics: Adult; Animals; Brain; Creutzfeldt-Jakob Syndrome; Female; Fixatives; Formaldehyde; Histological Tec

1986