formaldehyde has been researched along with Constriction, Pathologic in 21 studies
paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy
Constriction, Pathologic: The condition of an anatomical structure's being constricted beyond normal dimensions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It had less effect on tactile allodynia (CCI)." | 5.35 | Effects of norketamine enantiomers in rodent models of persistent pain. ( Crooks, PA; Hojomat, M; Holtman, JR; Johnson-Hardy, JK; Kleven, M; Wala, EP, 2008) |
| "Ambroxol's effects were compared with those of gabapentin." | 5.33 | Ambroxol, a Nav1.8-preferring Na(+) channel blocker, effectively suppresses pain symptoms in animal models of chronic, neuropathic and inflammatory pain. ( Arndt, K; Gaida, W; Klinder, K; Weiser, T, 2005) |
| "Neuropathic pain is a debilitating condition affecting millions of people around the world and is defined as pain that follows a lesion or dysfunction of the nervous system." | 5.33 | Identification of the alpha2-delta-1 subunit of voltage-dependent calcium channels as a molecular target for pain mediating the analgesic actions of pregabalin. ( Bramwell, S; Corradini, L; Cox, PJ; Dolphin, AC; England, S; Field, MJ; Hendrich, J; Kinloch, RA; Melrose, H; Offord, J; Stott, E; Su, TZ; Webb, T; Williams, D; Winks, J, 2006) |
| " In the present study, morphine (a low dose) was combined with S(+)- and R(-)-norketamine (sub-antinociceptive doses) and characterized utilizing rodent models of pain including: thermal nociception (the tail-flick test), peripheral neuropathy (chronic constriction nerve injury) and tonic inflammatory pain (the formalin test)." | 3.74 | Interaction between morphine and norketamine enantiomers in rodent models of nociception. ( Crooks, PA; Holtman, JR; Johnson-Hardy, J; Wala, EP, 2008) |
| ") decreased thermal hyperalgesia observed in carrageenan-induced inflammatory hypersensitivity without affecting paw edema, abolished acetic acid-induced writhing activity in mice, and was shown to reduce mechanical allodynia and thermal hyperalgesia observed in a model of post-operative hypersensitivity and formalin-induced spontaneous pain." | 3.72 | Assessing the role of metabotropic glutamate receptor 5 in multiple nociceptive modalities. ( Decker, MW; Gauvin, DM; Honore, P; Lynch, JJ; Mikusa, JP; Wade, CL; Wilson, SG; Wismer, CT; Zhu, CZ, 2004) |
| "There were 11 anal cancers (33 percent), 11 prostate cancers, 9 cervical or endometrial cancers, 1 bladder cancer, and 1 rectal cancer." | 2.71 | Formalin application in the treatment of chronic radiation-induced hemorrhagic proctitis--an effective but not risk-free procedure: a prospective study of 33 patients. ( Atienza, P; Bauer, P; Bourguignon, J; de Parades, V; Etienney, I; Meary, N; Mory, B; Sultan, S; Taouk, M; Thomas, C, 2005) |
| "1) In vivo bioavailability study: TC-2559 (3 mg/kg) had high absorption rate in rats with maximal total brain concentration reached over 4." | 1.37 | Enhanced inhibitory synaptic transmission in the spinal dorsal horn mediates antinociceptive effects of TC-2559. ( Cheng, LZ; Fan, J; Han, L; Huang, LT; Peng, LC; Wang, Y, 2011) |
| "It had less effect on tactile allodynia (CCI)." | 1.35 | Effects of norketamine enantiomers in rodent models of persistent pain. ( Crooks, PA; Hojomat, M; Holtman, JR; Johnson-Hardy, JK; Kleven, M; Wala, EP, 2008) |
| "Ambroxol's effects were compared with those of gabapentin." | 1.33 | Ambroxol, a Nav1.8-preferring Na(+) channel blocker, effectively suppresses pain symptoms in animal models of chronic, neuropathic and inflammatory pain. ( Arndt, K; Gaida, W; Klinder, K; Weiser, T, 2005) |
| "Neuropathic pain is a debilitating condition affecting millions of people around the world and is defined as pain that follows a lesion or dysfunction of the nervous system." | 1.33 | Identification of the alpha2-delta-1 subunit of voltage-dependent calcium channels as a molecular target for pain mediating the analgesic actions of pregabalin. ( Bramwell, S; Corradini, L; Cox, PJ; Dolphin, AC; England, S; Field, MJ; Hendrich, J; Kinloch, RA; Melrose, H; Offord, J; Stott, E; Su, TZ; Webb, T; Williams, D; Winks, J, 2006) |
| "Rectal strictures were successfully dilated in 2." | 1.30 | The surgical management of colorectal complications from irradiation for carcinoma of the cervix. ( Eu, KW; Ho, YH; Leong, A; Nyam, D; Seow, C; Yegappan, M, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (14.29) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 11 (52.38) | 29.6817 |
| 2010's | 4 (19.05) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Cortés-Montero, E | 1 |
| Rodríguez-Muñoz, M | 1 |
| Ruiz-Cantero, MDC | 1 |
| Cobos, EJ | 1 |
| Sánchez-Blázquez, P | 1 |
| Garzón-Niño, J | 1 |
| Li, W | 1 |
| Cai, J | 1 |
| Wang, BH | 1 |
| Huang, L | 1 |
| Fan, J | 2 |
| Wang, Y | 2 |
| Kataoka, K | 1 |
| Hara, K | 1 |
| Haranishi, Y | 1 |
| Terada, T | 1 |
| Sata, T | 1 |
| Holtman, JR | 3 |
| Crooks, PA | 3 |
| Johnson-Hardy, J | 1 |
| Wala, EP | 3 |
| Johnson-Hardy, JK | 1 |
| Hojomat, M | 1 |
| Kleven, M | 1 |
| Leo, S | 1 |
| Moechars, D | 1 |
| Callaerts-Vegh, Z | 1 |
| D'Hooge, R | 1 |
| Meert, T | 1 |
| Bonnefous, C | 1 |
| Payne, JE | 1 |
| Roppe, J | 1 |
| Zhuang, H | 1 |
| Chen, X | 1 |
| Symons, KT | 1 |
| Nguyen, PM | 1 |
| Sablad, M | 1 |
| Rozenkrants, N | 1 |
| Zhang, Y | 1 |
| Wang, L | 1 |
| Severance, D | 1 |
| Walsh, JP | 1 |
| Yazdani, N | 1 |
| Shiau, AK | 1 |
| Noble, SA | 1 |
| Rix, P | 1 |
| Rao, TS | 1 |
| Hassig, CA | 1 |
| Smith, ND | 1 |
| Cheng, LZ | 1 |
| Han, L | 1 |
| Huang, LT | 1 |
| Peng, LC | 1 |
| Dwoskin, LP | 1 |
| Dowell, C | 1 |
| Zhang, Z | 1 |
| McIntosh, JM | 1 |
| LEGRAND, R | 1 |
| VANDECASTEELE, J | 1 |
| DESRUELLES, J | 1 |
| BREYNAERT, R | 1 |
| Zhu, CZ | 1 |
| Wilson, SG | 1 |
| Mikusa, JP | 1 |
| Wismer, CT | 1 |
| Gauvin, DM | 1 |
| Lynch, JJ | 1 |
| Wade, CL | 1 |
| Decker, MW | 1 |
| Honore, P | 1 |
| de Parades, V | 1 |
| Etienney, I | 1 |
| Bauer, P | 1 |
| Bourguignon, J | 1 |
| Meary, N | 1 |
| Mory, B | 1 |
| Sultan, S | 1 |
| Taouk, M | 1 |
| Thomas, C | 1 |
| Atienza, P | 1 |
| Gaida, W | 1 |
| Klinder, K | 1 |
| Arndt, K | 1 |
| Weiser, T | 1 |
| Gadotti, VM | 1 |
| Schmeling, LO | 1 |
| Machado, C | 1 |
| Liz, FH | 1 |
| Filho, VC | 1 |
| Meyre-Silva, C | 1 |
| Santos, AR | 1 |
| Field, MJ | 1 |
| Cox, PJ | 1 |
| Stott, E | 1 |
| Melrose, H | 1 |
| Offord, J | 1 |
| Su, TZ | 1 |
| Bramwell, S | 1 |
| Corradini, L | 1 |
| England, S | 1 |
| Winks, J | 1 |
| Kinloch, RA | 1 |
| Hendrich, J | 1 |
| Dolphin, AC | 1 |
| Webb, T | 1 |
| Williams, D | 1 |
| Chen, YF | 1 |
| Zhang, H | 1 |
| Zhang, QY | 1 |
| Wu, JZ | 1 |
| Li, N | 1 |
| Rahman, K | 1 |
| Zheng, HC | 1 |
| Qin, LP | 1 |
| Yegappan, M | 1 |
| Ho, YH | 1 |
| Nyam, D | 1 |
| Leong, A | 1 |
| Eu, KW | 1 |
| Seow, C | 1 |
| Oiwa, H | 1 |
| Takamoto, S | 1 |
| Murakami, A | 1 |
| Tanaka, O | 1 |
| Furuse, A | 1 |
| Lucarotti, ME | 1 |
| Mountford, RA | 1 |
| Bartolo, DC | 1 |
| Ianovoĭ, VV | 1 |
| Axelsen, RA | 1 |
| Leditschke, JF | 1 |
| Burke, JR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Ambroxol on the Inflammatory Markers and Clinical Outcome of Patients With Diabetic Peripheral Neuropathy[NCT05558878] | 80 participants (Anticipated) | Interventional | 2022-10-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for formaldehyde and Constriction, Pathologic
| Article | Year |
|---|---|
Formalin application in the treatment of chronic radiation-induced hemorrhagic proctitis--an effective but not risk-free procedure: a prospective study of 33 patients.
Topics: Aged; Aged, 80 and over; Anus Diseases; Anus Neoplasms; Blood Transfusion; Constriction, Pathologic; | 2005 |
20 other studies available for formaldehyde and Constriction, Pathologic
| Article | Year |
|---|---|
Calmodulin Supports TRPA1 Channel Association with Opioid Receptors and Glutamate NMDA Receptors in the Nervous Tissue.
Topics: Animals; Calmodulin; Constriction, Pathologic; Formaldehyde; Glutamic Acid; Inflammation; Male; Mice | 2020 |
Antinociceptive effects of novel epibatidine analogs through activation of α4β2 nicotinic receptors.
Topics: Analgesics, Non-Narcotic; Animals; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Co | 2018 |
The antinociceptive effect of SNAP5114, a gamma-aminobutyric acid transporter-3 inhibitor, in rat experimental pain models.
Topics: Acute Pain; Analgesics; Animals; Anisoles; Behavior, Animal; Chronic Pain; Constriction, Pathologic; | 2013 |
Interaction between morphine and norketamine enantiomers in rodent models of nociception.
Topics: Analgesics, Opioid; Animals; Constriction, Pathologic; Dose-Response Relationship, Drug; Drug Combin | 2008 |
Effects of norketamine enantiomers in rodent models of persistent pain.
Topics: Animals; Behavior, Animal; Chronic Disease; Constriction, Pathologic; Dose-Response Relationship, Dr | 2008 |
Impairment of VGLUT2 but not VGLUT1 signaling reduces neuropathy-induced hypersensitivity.
Topics: Animals; Ataxia; Behavior, Animal; Carrageenan; Constriction, Pathologic; Formaldehyde; Hot Temperat | 2009 |
Discovery of inducible nitric oxide synthase (iNOS) inhibitor development candidate KD7332, part 1: Identification of a novel, potent, and selective series of quinolinone iNOS dimerization inhibitors that are orally active in rodent pain models.
Topics: Administration, Oral; Animals; Cell Line; Constriction, Pathologic; Disease Models, Animal; Drug Dis | 2009 |
Enhanced inhibitory synaptic transmission in the spinal dorsal horn mediates antinociceptive effects of TC-2559.
Topics: Analgesics; Animals; Biological Availability; Brain; Constriction, Pathologic; Dose-Response Relatio | 2011 |
The novel small molecule α9α10 nicotinic acetylcholine receptor antagonist ZZ-204G is analgesic.
Topics: Alkynes; Analgesics; Animals; Behavior, Animal; Benzene; Constriction, Pathologic; Feasibility Studi | 2011 |
[Stenosis of the aortic isthmus; Crafoord-Gross operation and reestablishment of vascular continuity by a formol graft].
Topics: Animals; Aortic Coarctation; Coleoptera; Constriction, Pathologic; Formaldehyde; Humans; Transplants | 1956 |
Assessing the role of metabotropic glutamate receptor 5 in multiple nociceptive modalities.
Topics: Acetic Acid; Animals; Carrageenan; Central Nervous System; Constriction, Pathologic; Edema; Formalde | 2004 |
Ambroxol, a Nav1.8-preferring Na(+) channel blocker, effectively suppresses pain symptoms in animal models of chronic, neuropathic and inflammatory pain.
Topics: Ambroxol; Amines; Analgesics; Animals; Behavior, Animal; Constriction, Pathologic; Cyclohexanecarbox | 2005 |
Antinociceptive action of the extract and the flavonoid quercitrin isolated from Bauhinia microstachya leaves.
Topics: Abdominal Muscles; Acetic Acid; Analgesics; Animals; Bauhinia; Carrageenan; Constriction, Pathologic | 2005 |
Identification of the alpha2-delta-1 subunit of voltage-dependent calcium channels as a molecular target for pain mediating the analgesic actions of pregabalin.
Topics: Amino Acid Sequence; Analgesics; Animals; Arginine; Autoradiography; Base Sequence; Calcium Channels | 2006 |
Antinociceptive activity of n-butanol fraction from MeOH extracts of Paederia scandens in mice.
Topics: 1-Butanol; Acetic Acid; Analgesics; Analgesics, Opioid; Animals; Capsaicin; Constriction, Pathologic | 2007 |
The surgical management of colorectal complications from irradiation for carcinoma of the cervix.
Topics: Aged; Constriction, Pathologic; Enteritis; Female; Formaldehyde; Gastrointestinal Hemorrhage; Humans | 1998 |
Experimental study of small arterial anastomosis with gelatin-resorcin-formaldehyde glue and collagen sheet.
Topics: Anastomosis, Surgical; Animals; Carotid Artery, Common; Collagen; Constriction, Pathologic; Dogs; Dr | 2001 |
Surgical management of intestinal radiation injury.
Topics: Adult; Aged; Aged, 80 and over; Constriction, Pathologic; Female; Follow-Up Studies; Formaldehyde; H | 1991 |
[Treatment of the sequelae of an extensive chemical burn of the large intestine].
Topics: Adolescent; Burns, Chemical; Constriction, Pathologic; Enema; Female; Formaldehyde; Humans; Intestin | 1986 |
Renal and urinary tract complications following the intravesical instillation of formalin.
Topics: Administration, Intravesical; Antineoplastic Combined Chemotherapy Protocols; Child; Constriction, P | 1986 |