Page last updated: 2024-10-18

formaldehyde and Colonic Neoplasms

formaldehyde has been researched along with Colonic Neoplasms in 73 studies

paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy

Colonic Neoplasms: Tumors or cancer of the COLON.

Research Excerpts

ExcerptRelevanceReference
"Case 2: A 64-year-old man with stage IV colon cancer (multiple para-aortic lymph node metastases and direct abdominal wall invasion) underwent non-curative surgery in May 2006."1.46Long-lasting complete response status of advanced stage IV gall bladder cancer and colon cancer after combined treatment including autologous formalin-fixed tumor vaccine: two case reports. ( Imaoka, Y; Kuranishi, F; Miyazaki, T; Ohno, T; Yasuda, H, 2017)
"Fifteen colon cancer tissues were collected, divided into two mirrored samples and either formalin fixed (FFPE) or PAXgene fixed (PFPE) before paraffin embedding."1.40Evaluation of colon cancer histomorphology: a comparison between formalin and PAXgene tissue fixation by an international ring trial. ( Asslaber, M; Babaryka, G; Becker, I; Becker, KF; Bodó, K; Carneiro, F; Ciniselli, CM; den Bakker, M; den Hollander, J; Drecoll, E; Esposito, I; Fend, F; Gündisch, S; Höfler, H; Kap, M; Kayser, G; Langer, R; Lopes, JM; Lugli, A; May, AM; Neumann, J; Perren, A; Pizzamiglio, S; Reu, S; Richter, T; Riegman, P; Schott, C; Slotta-Huspenina, J; Sobin, L; Specht, K; Verderio, P; Viertler, C; Zatloukal, K, 2014)
"Its expression in colon cancer cells and metastases is conserved."1.36Analytical performance of a qRT-PCR assay to detect guanylyl cyclase C in FFPE lymph nodes of patients with colon cancer. ( Beaudry, G; Beaulieu, M; Bertrand, N; Desaulniers, M; Deschesnes, RG; Garon, G; Haince, JF; Holzer, TJ; Houde, M, 2010)
"In view of recent findings of nasal cancer in rats exposed to formaldehyde vapors, we investigated the proportionate mortality experience of embalmers licensed to practice in New York State."1.27Mortality patterns among embalmers. ( Fraumeni, JF; Walrath, J, 1983)

Research

Studies (73)

TimeframeStudies, this research(%)All Research%
pre-199010 (13.70)18.7374
1990's12 (16.44)18.2507
2000's18 (24.66)29.6817
2010's31 (42.47)24.3611
2020's2 (2.74)2.80

Authors

AuthorsStudies
Patil, S1
Lis, LG1
Schumacher, RJ1
Norris, BJ1
Morgan, ML1
Cuellar, RA1
Blazar, BR1
Suryanarayanan, R1
Gurvich, VJ1
Georg, GI1
Burns, JA1
Li, Y1
Cheney, CA1
Ou, Y1
Franlin-Pfeifer, LL1
Kuklin, N1
Zhang, ZQ1
Okubo, A1
Sone, S1
Tanaka, M1
Ogura, T1
Dias, AR1
Pereira, MA1
Mello, ES1
Cecconello, I1
Ribeiro-Jr, U1
Nahas, SC1
Pessanha, S1
Braga, D1
Ensina, A1
Silva, J1
Vilchez, J1
Montenegro, C1
Barbosa, S1
Carvalho, ML1
Dias, A1
Lazarus, J1
Akiska, Y1
Perusina Lanfranca, M1
Delrosario, L1
Sun, L1
Long, D1
Shi, J1
Crawford, H1
Di Magliano, MP1
Zou, W1
Frankel, T1
Imaoka, Y1
Kuranishi, F1
Miyazaki, T1
Yasuda, H1
Ohno, T1
Bonnet, E1
Moutet, ML1
Baulard, C1
Bacq-Daian, D1
Sandron, F1
Mesrob, L1
Fin, B1
Delépine, M1
Palomares, MA1
Jubin, C1
Blanché, H1
Meyer, V1
Boland, A1
Olaso, R1
Deleuze, JF1
Mathieson, W1
Mommaerts, K1
Trouet, JM1
Mathay, C1
Guan, P1
Carithers, LJ1
Rohrer, D1
Valley, DR1
Blanski, A1
Jewell, S1
Moore, HM1
Betsou, F1
Gerdes, MJ2
Sevinsky, CJ1
Sood, A1
Adak, S1
Bello, MO1
Bordwell, A1
Can, A1
Corwin, A1
Dinn, S1
Filkins, RJ1
Hollman, D1
Kamath, V1
Kaanumalle, S1
Kenny, K1
Larsen, M1
Lazare, M1
Li, Q1
Lowes, C1
McCulloch, CC1
McDonough, E1
Montalto, MC1
Pang, Z1
Rittscher, J1
Santamaria-Pang, A1
Sarachan, BD1
Seel, ML1
Seppo, A1
Shaikh, K1
Sui, Y1
Zhang, J1
Ginty, F1
Oue, N1
Anami, K1
Schetter, AJ1
Moehler, M1
Okayama, H1
Khan, MA1
Bowman, ED1
Mueller, A1
Schad, A1
Shimomura, M1
Hinoi, T1
Aoyagi, K1
Sasaki, H1
Okajima, M1
Ohdan, H1
Galle, PR1
Yasui, W1
Harris, CC1
Schubert, W1
Dress, A1
Ruonala, M1
Krusche, A1
Hillert, R1
Gieseler, A1
Walden, P1
Warford, A1
Akbar, H1
Riberio, D1
Plamadeala, V1
Huang, S1
McCreary, SM1
Reitze, NJ1
Ewing, AL1
Gabrin, MJ1
Bennett, AE1
Mulligan, JM2
Wilson, CL1
Wang, D1
Gündisch, S2
Slotta-Huspenina, J1
Verderio, P1
Ciniselli, CM1
Pizzamiglio, S1
Schott, C2
Drecoll, E1
Viertler, C2
Zatloukal, K2
Kap, M2
Riegman, P2
Esposito, I1
Specht, K1
Babaryka, G1
Asslaber, M1
Bodó, K1
den Bakker, M1
den Hollander, J1
Fend, F1
Neumann, J1
Reu, S1
Perren, A1
Langer, R2
Lugli, A1
Becker, I1
Richter, T1
Kayser, G1
May, AM1
Carneiro, F1
Lopes, JM1
Sobin, L1
Höfler, H1
Becker, KF2
Di Narzo, AF1
Tejpar, S2
Rossi, S1
Yan, P1
Popovici, V1
Wirapati, P1
Budinska, E1
Xie, T1
Estrella, H1
Pavlicek, A1
Mao, M1
Martin, E1
Scott, W1
Bosman, FT3
Roth, A1
Delorenzi, M1
Kong, H1
Zhu, M1
Cui, F1
Wang, S1
Gao, X1
Lu, S1
Wu, Y1
Zhu, H1
Buck, A1
Balluff, B1
Voss, A1
Zitzelsberger, H1
Aichler, M1
Walch, A1
Norderval, S1
Solstad, ØB1
Hermansen, M1
Steigen, SE1
Chen, X1
Deane, NG1
Lewis, KB1
Li, J2
Zhu, J1
Washington, MK2
Beauchamp, RD1
Cederbye, CN1
Palshof, JA1
Hansen, TP1
Duun-Henriksen, AK1
Linnemann, D1
Stenvang, J1
Nielsen, DL1
Brünner, N1
Viuff, BM1
Lee, HM1
Kim, CW1
Hwang, KA1
Choi, DW1
Choi, KC1
Carlson, GE1
Martin, EW1
Shirure, VS1
Malgor, R1
Resto, VA1
Goetz, DJ1
Burdick, MM1
Khanmohammadi, M1
Garmarudi, AB1
Ghasemi, K1
Jaliseh, HK1
Kaviani, A1
Bodo, J1
Durkin, L1
Hsi, ED1
Constantinou, P1
Dacosta, RS1
Wilson, BC1
Dufort, S1
Richard, MJ1
de Fraipont, F1
Sprung, RW1
Brock, JW1
Tanksley, JP1
Li, M1
Slebos, RJ1
Liebler, DC1
Roberts, L1
Bowers, J1
Sensinger, K1
Lisowski, A1
Getts, R1
Anderson, MG1
Franklin, WA1
Haney, J1
Sugita, M1
Bemis, L1
Jimeno, A1
Messersmith, WA1
Beaulieu, M1
Desaulniers, M1
Bertrand, N1
Deschesnes, RG1
Beaudry, G1
Garon, G1
Haince, JF1
Houde, M1
Holzer, TJ1
Denouël, A1
Boissière-Michot, F1
Rochaix, P1
Bibeau, F1
Boulle, N1
Wiśniewski, JR1
Ostasiewicz, P1
Mann, M1
Oltedal, S1
Aasprong, OG1
Møller, JH1
Kørner, H1
Gilje, B1
Tjensvoll, K1
Birkemeyer, EM1
Heikkilä, R1
Smaaland, R1
Nordgård, O1
Rodríguez-Rigueiro, T1
Valladares-Ayerbes, M1
Haz-Conde, M1
Blanco, M1
Aparicio, G1
Fernández-Puente, P1
Blanco, FJ1
Lorenzo, MJ1
Aparicio, LA1
Figueroa, A1
Kennedy, RD1
Bylesjo, M1
Kerr, P1
Davison, T1
Black, JM1
Kay, EW1
Holt, RJ1
Proutski, V1
Ahdesmaki, M1
Farztdinov, V1
Goffard, N1
Hey, P1
McDyer, F1
Mulligan, K1
Mussen, J1
O'Brien, E1
Oliver, G1
Walker, SM1
Wilson, C1
Winter, A1
O'Donoghue, D1
Mulcahy, H1
O'Sullivan, J1
Sheahan, K1
Hyland, J1
Dhir, R1
Bathe, OF1
Winqvist, O1
Manne, U1
Shanmugam, C1
Ramaswamy, S1
Leon, EJ1
Smith, WI1
McDermott, U1
Wilson, RH1
Longley, D1
Marshall, J1
Cummins, R1
Sargent, DJ1
Johnston, PG1
Harkin, DP1
Krijgsman, O1
Israeli, D1
Haan, JC1
van Essen, HF1
Smeets, SJ1
Eijk, PP1
Steenbergen, RD1
Kok, K1
Meijer, GA1
Ylstra, B1
Adams, MD1
Veigl, ML1
Wang, Z1
Molyneux, N1
Sun, S1
Guda, K1
Yu, X1
Markowitz, SD1
Willis, J1
Zhang, JZ1
Bryce, NS1
Lanzirotti, A1
Chen, CK1
Paterson, D1
de Jonge, MD1
Howard, DL1
Hambley, TW1
Hauck, S1
Sarioglu, H1
Schuster, T1
Reischauer, B1
Rosenberg, R1
Verhoef, C1
Mischinger, HJ1
Williams, SS1
Zimmerman, RL1
Bibbo, M1
BARBOSANDE, C1
Bibikova, M2
Talantov, D1
Chudin, E2
Yeakley, JM2
Chen, J2
Doucet, D1
Wickham, E2
Atkins, D1
Barker, D1
Chee, M1
Wang, Y1
Fan, JB2
Wang-Rodriguez, J1
Wang, F1
Mamon, H1
Kulke, MH1
Harris, L1
Maher, E1
Wang, L1
Makrigiorgos, GM1
Prieto, DA1
Hood, BL1
Darfler, MM1
Guiel, TG1
Lucas, DA1
Conrads, TP1
Veenstra, TD1
Krizman, DB1
Stanta, G1
Mucelli, SP1
Petrera, F1
Bonin, S1
Bussolati, G1
Ly, E1
Piot, O1
Wolthuis, R1
Durlach, A1
Bernard, P1
Manfait, M1
Matsuda, A1
Kuno, A1
Ishida, H1
Kawamoto, T1
Shoda, J1
Hirabayashi, J1
Liebling, T1
Rosenman, KD1
Pastides, H1
Griffith, RG1
Lemeshow, S1
Walrath, J1
Fraumeni, JF1
Ofner, D1
Bankfalvi, A1
Riehemann, K1
Bier, B1
Böcker, W1
Schmid, KW1
Terada, T1
Shimizu, K1
Izumi, R1
Nakanuma, Y1
Kim, YW1
Lee, S1
Park, JH1
Yoon, TY1
Park, YK1
Yang, MH1
Vissers, CJ1
Flohil, CC1
de Jong, AA1
Dinjens, WN1
Noguchi, M1
Furuya, S1
Takeuchi, T1
Hirohashi, S1
Vince, DG1
Tbakhi, A1
Gaddipati, A1
Cothren, RM1
Cornhill, JF1
Tubbs, RR1
Schoen, RE1
Gerber, LD1
Margulies, C1
McKay, JA1
Murray, GI1
Keith, WN1
McLeod, HL1
Trézl, L1
Hullán, L1
Szarvas, T1
Csiba, A1
Szende, B1
Hashizume, K1
Hatanaka, Y1
Kamihara, Y1
Tani, Y1
Magdinier, F1
Wolffe, AP1
Kim, DH1
Hong, YK1
Egholm, M1
Strauss, WM1
Grab, DJ1
Zedeck, MS1
Wagner, L1
Base, W1
Wiesholzer, M1
Sexl, V1
Bognar, H1
Worman, CP1
Moerkerk, PT1
Kessels, HJ1
ten Kate, J1
de Goeij, AF1
D'Errico, A1
Facchini, A1
Meliconi, R1
Grigioni, FW1
Ferrone, S1
Steven, FS1
Ali, H1
Griffin, MM1
Crissman, JD1
Zarbo, RJ1
Niebylski, CD1
Corbett, T1
Weaver, D1
Herbert, DJ1
Nishiyama, RH1
Bagwell, CB1
Munson, ME1
Hitchcox, SA1
Lovett, EJ1
Goelz, SE1
Hamilton, SR1
Vogelstein, B1
Moullé, P1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Lymph Node Yield After Specimen Fixation With Carnoy's Solution and 10% Neutral Buffered Formaldehyde in Patients With Colorectal Cancer or Gastric Adenocarcinoma Specimens: a Randomized Trial[NCT02629315]130 participants (Actual)Interventional2012-05-10Completed
Phase 2 Study of Pembrolizumab and Brentuximab Vedotin in Subjects With Relapsed/Refractory CD30 Positive T-cell Lymphoma[NCT05313243]Phase 243 participants (Anticipated)Interventional2023-07-10Recruiting
Complete Pathologic Response Rectal Cancers EYSAC.1 Study[NCT03351959]1,000 participants (Anticipated)Observational2018-01-01Recruiting
The Predictive Value of Guangzhou Panel for Recurrence in Early-stage Colorectal Cancer[NCT03923335]287 participants (Anticipated)Observational2019-04-30Not yet recruiting
Phase II Trial of Pemetrexed and Bevacizumab for Recurrent Ovarian and Primary Peritoneal Carcinoma[NCT00868192]Phase 238 participants (Actual)Interventional2008-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Overall Response Rate

"Overall response rate = complete response + partial response~Complete response = disappearance of all target and non-target lesions and no evidence of new lesions documented by two disease assessments at least 4 weeks apart.~Partial response = at least a 30% decrease in the sum of the longest dimensions (LD) of all target measurable lesions taking as reference the baseline sum of LD. There can be non unequivocal progression of non-target lesions and no new lesions." (NCT00868192)
Timeframe: 6 months

Interventionpercentage of participants (Number)
Pemetrexed and Bevacizumab41

Overall Survival (OS)

OS = observed length of time from entry into the study to death or date of last contact (NCT00868192)
Timeframe: 12 months

Interventionpercentage of participants (Number)
Pemetrexed and Bevacizumab79

Overall Survival (OS)

OS = observed length of time from entry into the study to death or date of last contact (NCT00868192)
Timeframe: Median follow-up was 25.7 months (range 3.0-47.2 months)

Interventionmonths (Median)
Pemetrexed and Bevacizumab25.7

Progression-free Survival (PFS)

PFS = Period from study entry until disease progression, death, or date of last contact (NCT00868192)
Timeframe: 6 months

Interventionpercentage of participants (Number)
Pemetrexed and Bevacizumab56

Progression-free Survival (PFS)

PFS = Period from study entry until disease progression, death, or date of last contact (NCT00868192)
Timeframe: Median follow-up was 25.7 months (range 3.0-47.2 months)

Interventionmonths (Median)
Pemetrexed and Bevacizumab7.9

CA-125 Response

A CA-125 response was defined as at least a 50% reduction in CA-125 levels from a pretreatment sample following guidelines described by the Gynecological Cancer Intergroup. (NCT00868192)
Timeframe: 6 months

Interventionparticipants (Number)
50% CA-125 response75% CA-125 responseNo CA-125 response
Pemetrexed and Bevacizumab1782

Distribution of Overall Survival (OS)

OS = observed length of time from entry into the study to death or date of last contact (NCT00868192)
Timeframe: Median follow-up was 25.7 months (range 3.0-47.2 months)

Interventionmonths (Median)
Platinum-free interval of <6 monthsPlatinum-free interval of 6-12 monthsPlatinum-free interval of >12 months
Pemetrexed and Bevacizumab16.724.928.0

Distribution of Progression-free Survival (PFS)

PFS = Period from study entry until disease progression, death, or date of last contact (NCT00868192)
Timeframe: Median follow-up was 25.7 months (range 3.0-47.2 months)

Interventionmonths (Median)
Platinum-free interval of <6 monthsPlatinum-free interval of 6-12 monthsPlatinum-free interval of >12 months
Pemetrexed and Bevacizumab6.74.716.8

Frequency of Clinical Response

As measured by RECIST criteria (NCT00868192)
Timeframe: 6 months

Interventionparticipants (Number)
Complete responsePartial responseStable diseaseProgressive disease
Pemetrexed and Bevacizumab014182

Toxicity Associated With Bevacizumab and Pemetrexed

Detailed serious adverse events and other adverse events are shown in the adverse event module of the results. (NCT00868192)
Timeframe: 6 months

Interventionpercentage of participants (Number)
Grade 3/4 hematologic toxicityMost common non-hematologic toxicity - fatigueGrade 3 renal toxicityGastrointestinal toxicitySubsequently developed hematologic malignancies
Pemetrexed and Bevacizumab53946916

Reviews

1 review available for formaldehyde and Colonic Neoplasms

ArticleYear
Antigen retrieval, blocking, detection and visualisation systems in immunohistochemistry: a review and practical evaluation of tyramide and rolling circle amplification systems.
    Methods (San Diego, Calif.), 2014, Volume: 70, Issue:1

    Topics: Animals; Antibodies; Antigens; Antigens, CD20; Breast Neoplasms; Colonic Neoplasms; Female; Formalde

2014

Trials

1 trial available for formaldehyde and Colonic Neoplasms

ArticleYear
CARNOY'S SOLUTION INCREASES LYMPH NODES COUNT IN COLON CANCER SPECIMENS WHEN COMPARED TO FORMALIN FIXATION: A RANDOMIZED TRIAL.
    Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery, 2022, Volume: 35

    Topics: Acetic Acid; Adenocarcinoma; Chloroform; Colonic Neoplasms; Ethanol; Formaldehyde; Humans; Lymph Nod

2022

Other Studies

71 other studies available for formaldehyde and Colonic Neoplasms

ArticleYear
Phosphonooxymethyl Prodrug of Triptolide: Synthesis, Physicochemical Characterization, and Efficacy in Human Colon Adenocarcinoma and Ovarian Cancer Xenografts.
    Journal of medicinal chemistry, 2015, Dec-10, Volume: 58, Issue:23

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line, Tumor; Colon; Colonic Neoplasms; Diterpen

2015
Choice of fixative is crucial to successful immunohistochemical detection of phosphoproteins in paraffin-embedded tumor tissues.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2009, Volume: 57, Issue:3

    Topics: Animals; Biomarkers, Tumor; Breast Neoplasms; Colonic Neoplasms; Data Interpretation, Statistical; F

2009
Membrane-associated interleukin 1 alpha as a mediator of tumor cell killing by human blood monocytes fixed with paraformaldehyde.
    Cancer research, 1989, Jan-15, Volume: 49, Issue:2

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Cell Communication; Cell Line; Cell Membrane; Colonic Neoplasms;

1989
A non-destructive X-ray fluorescence method of analysis of formalin fixed-paraffin embedded biopsied samples for biomarkers for breast and colon cancer.
    Talanta, 2023, Aug-01, Volume: 260

    Topics: Biomarkers; Colonic Neoplasms; Formaldehyde; Humans; Paraffin Embedding; Tissue Fixation; X-Rays

2023
Optimization, Design and Avoiding Pitfalls in Manual Multiplex Fluorescent Immunohistochemistry.
    Journal of visualized experiments : JoVE, 2019, 07-26, Issue:149

    Topics: Antibodies; Colonic Neoplasms; Fluorescent Antibody Technique; Formaldehyde; Humans; Immunohistochem

2019
Long-lasting complete response status of advanced stage IV gall bladder cancer and colon cancer after combined treatment including autologous formalin-fixed tumor vaccine: two case reports.
    World journal of surgical oncology, 2017, Sep-11, Volume: 15, Issue:1

    Topics: Abdominal Wall; Cancer Vaccines; Colonic Neoplasms; Combined Modality Therapy; Female; Formaldehyde;

2017
Performance comparison of three DNA extraction kits on human whole-exome data from formalin-fixed paraffin-embedded normal and tumor samples.
    PloS one, 2018, Volume: 13, Issue:4

    Topics: Colon; Colonic Neoplasms; Computational Biology; Cryopreservation; DNA; DNA, Neoplasm; Exome Sequenc

2018
Cold Ischemia Score: An mRNA Assay for the Detection of Extended Cold Ischemia in Formalin-Fixed, Paraffin-Embedded Tissue.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2019, Volume: 67, Issue:3

    Topics: Cold Ischemia; Colonic Neoplasms; Female; Fixatives; Formaldehyde; Humans; Kidney Neoplasms; Male; N

2019
Highly multiplexed single-cell analysis of formalin-fixed, paraffin-embedded cancer tissue.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Jul-16, Volume: 110, Issue:29

    Topics: 3,3'-Diaminobenzidine; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Fem

2013
High miR-21 expression from FFPE tissues is associated with poor survival and response to adjuvant chemotherapy in colon cancer.
    International journal of cancer, 2014, Apr-15, Volume: 134, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Chemotherapy, Adjuvant; Colonic Neoplasms; Female

2014
Imaging cycler microscopy.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Jan-14, Volume: 111, Issue:2

    Topics: Biomarkers, Tumor; Breast Neoplasms; Colonic Neoplasms; Female; Formaldehyde; Humans; Microscopy, Fl

2014
Reply to Schubert et al.: Regarding critique of highly multiplexed technologies.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Jan-14, Volume: 111, Issue:2

    Topics: Biomarkers, Tumor; Breast Neoplasms; Colonic Neoplasms; Female; Formaldehyde; Humans; Microscopy, Fl

2014
Analytical performance of a formalin-fixed paraffin-embedded tissue-based 634-probe prognostic assay for predicting outcome of patients with stage II colon cancer.
    Applied immunohistochemistry & molecular morphology : AIMM, 2014, Volume: 22, Issue:4

    Topics: Biomarkers, Tumor; Colonic Neoplasms; DNA, Complementary; DNA, Neoplasm; Formaldehyde; Gene Expressi

2014
Evaluation of colon cancer histomorphology: a comparison between formalin and PAXgene tissue fixation by an international ring trial.
    Virchows Archiv : an international journal of pathology, 2014, Volume: 465, Issue:5

    Topics: Adenocarcinoma, Mucinous; Colonic Neoplasms; Formaldehyde; Humans; Observer Variation; Paraffin Embe

2014
Test of four colon cancer risk-scores in formalin fixed paraffin embedded microarray gene expression data.
    Journal of the National Cancer Institute, 2014, Volume: 106, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Area Under Curve; Biomarkers, Tumor; Colonic Neo

2014
Quantitative assessment of short amplicons in FFPE-derived long-chain RNA.
    Scientific reports, 2014, Nov-28, Volume: 4

    Topics: Colonic Neoplasms; Colorectal Neoplasms; Formaldehyde; Humans; Paraffin Embedding; Rectal Neoplasms;

2014
How Suitable is Matrix-Assisted Laser Desorption/Ionization-Time-of-Flight for Metabolite Imaging from Clinical Formalin-Fixed and Paraffin-Embedded Tissue Samples in Comparison to Matrix-Assisted Laser Desorption/Ionization-Fourier Transform Ion Cyclotro
    Analytical chemistry, 2016, 05-17, Volume: 88, Issue:10

    Topics: Biomarkers; Colonic Neoplasms; Esophageal Neoplasms; Formaldehyde; Fourier Analysis; Humans; Image P

2016
Increased lymph node retrieval decreases adjuvant chemotherapy rate for stage II colon cancer.
    Scandinavian journal of gastroenterology, 2016, Volume: 51, Issue:8

    Topics: Chemotherapy, Adjuvant; Colonic Neoplasms; DNA; Fixatives; Formaldehyde; Humans; Immunohistochemistr

2016
Comparison of Nanostring nCounter® Data on FFPE Colon Cancer Samples and Affymetrix Microarray Data on Matched Frozen Tissues.
    PloS one, 2016, Volume: 11, Issue:5

    Topics: Colonic Neoplasms; Formaldehyde; Frozen Sections; Gene Expression Regulation, Neoplastic; Humans; Ol

2016
Antibody validation and scoring guidelines for ABCG2 immunohistochemical staining in formalin-fixed paraffin-embedded colon cancer tissue.
    Scientific reports, 2016, 06-03, Volume: 6

    Topics: Antibodies, Monoclonal, Murine-Derived; Antibody Specificity; ATP Binding Cassette Transporter, Subf

2016
Three components of cigarette smoke altered the growth and apoptosis of metastatic colon cancer cells via inducing the synthesis of reactive oxygen species and endoplasmic reticulum stress.
    Environmental toxicology and pharmacology, 2016, Volume: 45

    Topics: Apoptosis; bcl-2-Associated X Protein; Benzene; Butadienes; Cell Line, Tumor; Cell Proliferation; Co

2016
Dynamic biochemical tissue analysis detects functional L-selectin ligands on colon cancer tissues.
    PloS one, 2017, Volume: 12, Issue:3

    Topics: Adenocarcinoma, Mucinous; Adenocarcinoma, Papillary; Biochemistry; Carcinoma, Signet Ring Cell; Colo

2017
Diagnosis of colon cancer by attenuated total reflectance-Fourier transform infrared microspectroscopy and soft independent modeling of class analogy.
    Medical oncology (Northwood, London, England), 2009, Volume: 26, Issue:3

    Topics: Colonic Neoplasms; Formaldehyde; Histocytochemistry; Humans; Models, Statistical; Paraffin Embedding

2009
Quantitative in situ detection of phosphoproteins in fixed tissues using quantum dot technology.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2009, Volume: 57, Issue:7

    Topics: Animals; Antineoplastic Agents; Bone Marrow; Calibration; Cell Line; Colonic Neoplasms; Fixatives; f

2009
Extending immunofluorescence detection limits in whole paraffin-embedded formalin fixed tissues using hyperspectral confocal fluorescence imaging.
    Journal of microscopy, 2009, Volume: 234, Issue:2

    Topics: 3,3'-Diaminobenzidine; Adenocarcinoma; Animals; Antibodies, Neoplasm; Cell Nucleus; Colonic Neoplasm

2009
Pyrosequencing method to detect KRAS mutation in formalin-fixed and paraffin-embedded tumor tissues.
    Analytical biochemistry, 2009, Aug-15, Volume: 391, Issue:2

    Topics: Base Sequence; Cell Line, Tumor; Colonic Neoplasms; DNA Mutational Analysis; ErbB Receptors; Fixativ

2009
Equivalence of protein inventories obtained from formalin-fixed paraffin-embedded and frozen tissue in multidimensional liquid chromatography-tandem mass spectrometry shotgun proteomic analysis.
    Molecular & cellular proteomics : MCP, 2009, Volume: 8, Issue:8

    Topics: Adenoma; Chromatography, Liquid; Colonic Neoplasms; Fixatives; Formaldehyde; Frozen Sections; Humans

2009
Identification of methods for use of formalin-fixed, paraffin-embedded tissue samples in RNA expression profiling.
    Genomics, 2009, Volume: 94, Issue:5

    Topics: Colonic Neoplasms; Formaldehyde; Freezing; Gene Expression Profiling; Humans; Lung Neoplasms; Oligon

2009
KRAS mutation: comparison of testing methods and tissue sampling techniques in colon cancer.
    The Journal of molecular diagnostics : JMD, 2010, Volume: 12, Issue:1

    Topics: Carcinoma; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Colonic Neoplasms; DNA; DNA Mutational

2010
Analytical performance of a qRT-PCR assay to detect guanylyl cyclase C in FFPE lymph nodes of patients with colon cancer.
    Diagnostic molecular pathology : the American journal of surgical pathology, part B, 2010, Volume: 19, Issue:1

    Topics: Colonic Neoplasms; Fixatives; Formaldehyde; Guanylate Cyclase; Humans; Lymph Nodes; Paraffin Embeddi

2010
An alternative fixative to formalin fixation for molecular applications: the RCL2(®)-CS100 approach.
    Methods in molecular biology (Clifton, N.J.), 2011, Volume: 724

    Topics: Colonic Neoplasms; DNA; Fixatives; Formaldehyde; Frozen Sections; Humans; Immunohistochemistry; Kera

2011
High recovery FASP applied to the proteomic analysis of microdissected formalin fixed paraffin embedded cancer tissues retrieves known colon cancer markers.
    Journal of proteome research, 2011, Jul-01, Volume: 10, Issue:7

    Topics: Biomarkers, Tumor; Carcinoembryonic Antigen; CD55 Antigens; Cell Count; Cell Line, Tumor; Chromatogr

2011
Heterogeneous distribution of K-ras mutations in primary colon carcinomas: implications for EGFR-directed therapy.
    International journal of colorectal disease, 2011, Volume: 26, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Colonic Neoplasms; ErbB Receptors; Formaldehyde; Humans; Middle Aged

2011
A novel procedure for protein extraction from formalin-fixed paraffin-embedded tissues.
    Proteomics, 2011, Volume: 11, Issue:12

    Topics: Antigens; Biopsy; Blotting, Western; Colonic Neoplasms; Fixatives; Formaldehyde; Humans; Immunohisto

2011
Development and independent validation of a prognostic assay for stage II colon cancer using formalin-fixed paraffin-embedded tissue.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Dec-10, Volume: 29, Issue:35

    Topics: Aged; Colonic Neoplasms; Female; Formaldehyde; Gene Expression Profiling; Humans; Male; Middle Aged;

2011
CGH arrays compared for DNA isolated from formalin-fixed, paraffin-embedded material.
    Genes, chromosomes & cancer, 2012, Volume: 51, Issue:4

    Topics: Colonic Neoplasms; Comparative Genomic Hybridization; DNA; DNA Copy Number Variations; DNA, Neoplasm

2012
Global mutational profiling of formalin-fixed human colon cancers from a pathology archive.
    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 2012, Volume: 25, Issue:12

    Topics: Adenocarcinoma; Biological Specimen Banks; Colonic Neoplasms; DNA, Neoplasm; Feasibility Studies; Fo

2012
Getting to the core of platinum drug bio-distributions: the penetration of anti-cancer platinum complexes into spheroid tumour models.
    Metallomics : integrated biometal science, 2012, Volume: 4, Issue:11

    Topics: Anthraquinones; Cell Line, Tumor; Cisplatin; Colonic Neoplasms; Electricity; Female; Formaldehyde; H

2012
Variability of protein and phosphoprotein levels in clinical tissue specimens during the preanalytical phase.
    Journal of proteome research, 2012, Dec-07, Volume: 11, Issue:12

    Topics: Biomarkers, Tumor; Biopsy; Blotting, Western; Chromatography, Liquid; Cold Ischemia; Colon; Colonic

2012
BCA-225 immunostain: is it of value in liver fine needle aspiration?
    Analytical and quantitative cytology and histology, 2002, Volume: 24, Issue:5

    Topics: Adenocarcinoma; Biomarkers, Tumor; Biopsy, Needle; Carcinoma, Hepatocellular; Carcinoma, Neuroendocr

2002
[TRIAL TREATMENT OF CANCER].
    Revista brasileira de medicina, 1963, Volume: 20

    Topics: Carcinoma; Carcinoma, Squamous Cell; Colonic Neoplasms; Facial Neoplasms; Female; Formaldehyde; Geni

1963
Quantitative gene expression profiling in formalin-fixed, paraffin-embedded tissues using universal bead arrays.
    The American journal of pathology, 2004, Volume: 165, Issue:5

    Topics: Algorithms; Breast; Breast Neoplasms; Cell Line, Tumor; Cluster Analysis; Colon; Colonic Neoplasms;

2004
Gene expression profiles in formalin-fixed, paraffin-embedded tissues obtained with a novel assay for microarray analysis.
    Clinical chemistry, 2004, Volume: 50, Issue:12

    Topics: Adenocarcinoma; Breast Neoplasms; Colonic Neoplasms; Female; Fixatives; Formaldehyde; Gene Expressio

2004
Antiprimer quenching-based real-time PCR and its application to the analysis of clinical cancer samples.
    Clinical chemistry, 2006, Volume: 52, Issue:4

    Topics: Apolipoproteins B; Breast Neoplasms; Colonic Neoplasms; DNA; DNA Primers; Female; Fixatives; Fluores

2006
Liquid Tissue: proteomic profiling of formalin-fixed tissues.
    BioTechniques, 2005, Volume: Suppl

    Topics: Chromatography, Liquid; Colonic Neoplasms; Formaldehyde; Humans; Mass Spectrometry; Neoplasm Protein

2005
A novel fixative improves opportunities of nucleic acids and proteomic analysis in human archive's tissues.
    Diagnostic molecular pathology : the American journal of surgical pathology, part B, 2006, Volume: 15, Issue:2

    Topics: Base Sequence; Blotting, Western; Colonic Neoplasms; DNA Primers; DNA, Neoplasm; Electrophoresis, Ge

2006
Combination of FTIR spectral imaging and chemometrics for tumour detection from paraffin-embedded biopsies.
    The Analyst, 2008, Volume: 133, Issue:2

    Topics: Biomarkers, Tumor; Biopsy; Colonic Neoplasms; Fixatives; Formaldehyde; Humans; Neoplasms; Paraffin;

2008
Development of an all-in-one technology for glycan profiling targeting formalin-embedded tissue sections.
    Biochemical and biophysical research communications, 2008, May-30, Volume: 370, Issue:2

    Topics: Adenocarcinoma; Biomarkers; Cell Line, Tumor; Colonic Neoplasms; Dissection; Formaldehyde; Humans; L

2008
Cancer mortality among workers exposed to formaldehyde.
    American journal of industrial medicine, 1984, Volume: 5, Issue:6

    Topics: Aged; Cheek; Chemical Industry; Colonic Neoplasms; Formaldehyde; Humans; Male; Massachusetts; Middle

1984
Mortality patterns among embalmers.
    International journal of cancer, 1983, Apr-15, Volume: 31, Issue:4

    Topics: Adult; Age Factors; Aged; Colonic Neoplasms; Coronary Disease; Embalming; Formaldehyde; Humans; Lung

1983
Wet autoclave pretreatment improves the visualization of silver-stained nucleolar organizer-region-associated proteins in routinely formalin-fixed and paraffin-embedded tissues.
    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 1994, Volume: 7, Issue:9

    Topics: Adenocarcinoma; Breast Neoplasms; Carcinoma, Squamous Cell; Colonic Neoplasms; Formaldehyde; Histocy

1994
Methods in pathology. p53 expression in formalin-fixed, paraffin-embedded archival specimens of intrahepatic cholangiocarcinoma: retrieval of p53 antigenicity by microwave oven heating of tissue sections.
    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 1994, Volume: 7, Issue:2

    Topics: Antibodies, Monoclonal; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma; Cholangiocarcinoma

1994
An immunohistochemical study of the expression of p53 protein in colon cancer.
    Journal of Korean medical science, 1995, Volume: 10, Issue:3

    Topics: Adenocarcinoma; Adenoma; Adult; Biomarkers, Tumor; Colonic Neoplasms; Female; Formaldehyde; Humans;

1995
A new monoclonal antibody for specific immunocytochemical staining of nucleoli.
    Acta histochemica, 1996, Volume: 98, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Caco-2 Cells; Cell Nucleolus; Colonic Neoplasms; Deoxyribonucleases

1996
Modified formalin and methanol fixation methods for molecular biological and morphological analyses.
    Pathology international, 1997, Volume: 47, Issue:10

    Topics: Breast; Breast Neoplasms; Colon; Colonic Neoplasms; DNA; Fixatives; Formaldehyde; Gastric Mucosa; Hu

1997
Quantitative comparison of immunohistochemical staining intensity in tissues fixed in formalin and Histochoice.
    Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology, 1997, Volume: 15, Issue:2

    Topics: Analysis of Variance; Antigens, CD20; Carcinoma; Chromogranins; Colonic Neoplasms; Factor VIII; Fixa

1997
The pathologic measurement of polyp size is preferable to the endoscopic estimate.
    Gastrointestinal endoscopy, 1997, Volume: 46, Issue:6

    Topics: Adenomatous Polyps; Colon; Colonic Neoplasms; Colonic Polyps; Colonoscopy; Female; Formaldehyde; Hum

1997
Amplification of fluorescent in situ hybridisation signals in formalin fixed paraffin wax embedded sections of colon tumour using biotinylated tyramide.
    Molecular pathology : MP, 1997, Volume: 50, Issue:6

    Topics: Biotin; Chromosome Aberrations; Chromosomes, Human, Pair 9; Colonic Neoplasms; Formaldehyde; Humans;

1997
Determination of endogenous formaldehyde in plants (fruits) bound to L-arginine and its relation to the folate cycle, photosynthesis and apoptosis.
    Acta biologica Hungarica, 1998, Volume: 49, Issue:2-4

    Topics: Adenocarcinoma; Apoptosis; Arginine; Chromatography, High Pressure Liquid; Colonic Neoplasms; Folic

1998
Automated immunohistochemical staining of formalin-fixed and paraffin-embedded tissues using a catalyzed signal amplification method.
    Applied immunohistochemistry & molecular morphology : AIMM, 2001, Volume: 9, Issue:1

    Topics: Antigens; Breast Neoplasms; Colonic Neoplasms; Fixatives; Formaldehyde; Humans; Immunohistochemistry

2001
Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Apr-24, Volume: 98, Issue:9

    Topics: Acetylation; Antimetabolites, Antineoplastic; Azacitidine; Chromatin; Colonic Neoplasms; CpG Islands

2001
Non-disruptive PNA-FISH protocol for formalin-fixed and paraffin-embedded tissue sections.
    BioTechniques, 2001, Volume: 31, Issue:3

    Topics: Animals; Cell Nucleus; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 9; Colonic Neoplasms; D

2001
Organ-specific effects of the carcinogen methylazoxymethanol related to metabolism by nicotinamide adenine dinucleotide-dependent dehydrogenases.
    Cancer research, 1977, Volume: 37, Issue:11

    Topics: Alcohol Oxidoreductases; Animals; Azo Compounds; Colon; Colonic Neoplasms; Formaldehyde; In Vitro Te

1977
Detection of BLT substrate-specific proteases in individual human peripheral blood leucocytes and bone marrow cells. Application of the method to the classification of leukaemia.
    Journal of immunological methods, 1991, Sep-13, Volume: 142, Issue:2

    Topics: Antibodies, Monoclonal; Bone Marrow; Colonic Neoplasms; Diazonium Compounds; Formaldehyde; Granulocy

1991
Southern and dot blot analysis of DNA from formalin-fixed, paraffin-embedded tissue samples from colonic carcinomas.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1990, Volume: 58, Issue:5

    Topics: Blotting, Southern; Colonic Neoplasms; Densitometry; DNA Probes; DNA, Neoplasm; Electrophoresis, Aga

1990
Reactivity of monoclonal antibody (mAb) GD9 with a cytoplasmic antigen preserved in formalin-fixed, paraffin-embedded gastrointestinal tumors.
    Hybridoma, 1991, Volume: 10, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Antibody Specificity; Antigens, Neoplasm; Col

1991
The inhibition of a tumour cell surface protease in vivo and its re-activation by oxidation.
    British journal of cancer, 1988, Volume: 57, Issue:2

    Topics: Aminacrine; Carboxylic Ester Hydrolases; Colonic Neoplasms; Endopeptidases; Enzyme Reactivators; For

1988
Flow cytometric DNA analysis of colon adenocarcinomas: a comparative study of preparatory techniques.
    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 1988, Volume: 1, Issue:3

    Topics: Adenocarcinoma; Animals; Cell Line; Colonic Neoplasms; DNA; Ethanol; Flow Cytometry; Formaldehyde; H

1988
Effects of several commonly used fixatives on DNA and total nuclear protein analysis by flow cytometry.
    American journal of clinical pathology, 1989, Volume: 91, Issue:5

    Topics: Adenocarcinoma; Breast Neoplasms; Carcinoma, Squamous Cell; Colonic Neoplasms; DNA; Fixatives; Flow

1989
Purification of DNA from formaldehyde fixed and paraffin embedded human tissue.
    Biochemical and biophysical research communications, 1985, Jul-16, Volume: 130, Issue:1

    Topics: Carcinoma; Colonic Neoplasms; DNA; DNA Restriction Enzymes; DNA, Neoplasm; Fixatives; Formaldehyde;

1985
[Prevention by formol administration of anastomosis recurrence].
    La Presse medicale, 1971, Jun-05, Volume: 79, Issue:28

    Topics: Animals; Colonic Neoplasms; Formaldehyde; Neoplasm Recurrence, Local; Neoplasm Seeding; Neoplastic C

1971