Page last updated: 2024-10-18

formaldehyde and Chromosome-Defective Micronuclei

formaldehyde has been researched along with Chromosome-Defective Micronuclei in 18 studies

paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy

Research Excerpts

ExcerptRelevanceReference
"Formaldehyde (FA) was tested for a potential aneugenic activity in mammalian cells."5.37Does formaldehyde induce aneuploidy? ( Kühner, S; Linsenmeyer, R; Schütz, P; Speit, G, 2011)
"In this study, we assessed the toxic effects of formaldehyde (FA) on mouse bone marrow mesenchymal stem cells (BM-MSCs)."1.39Formaldehyde induces toxic effects and regulates the expression of damage response genes in BM-MSCs. ( Asai, G; Cui, Y; He, J; Li, Y; Liu, Y; Pan, Z; She, Y; Sun, S, 2013)
"Formaldehyde (FA) was tested for a potential aneugenic activity in mammalian cells."1.37Does formaldehyde induce aneuploidy? ( Kühner, S; Linsenmeyer, R; Schütz, P; Speit, G, 2011)
" Potential genotoxic effects in the lung were investigated as part of a comprehensive study on local and systemic toxic and genotoxic effects."1.36Inhalation of formaldehyde does not induce genotoxic effects in broncho-alveolar lavage (BAL) cells of rats. ( Ma-Hock, L; Neuss, S; Speit, G; Zeller, J, 2010)
"The three studies evaluated untreated cancer patients, welders, and pathologists/anatomists exposed to formaldehyde."1.34Exposure to genotoxic agents, host factors, and lifestyle influence the number of centromeric signals in micronuclei: a pooled re-analysis. ( Baciuchka-Palmaro, M; Bonassi, S; Botta, A; Iarmarcovai, G; Orsière, T; Sari-Minodier, I, 2007)
"Formaldehyde (FA) is a widely used industrial chemical."1.31Micronuclei frequencies in exfoliated nasal mucosa cells from pathology and anatomy laboratory workers exposed to formaldehyde. ( Burgaz, S; Cakmak, G; Erdem, O; Karakaya, AE; Yilmaz, M, 2001)
"Formaldehyde (FA) is a genotoxic substance, induces tumors in the nasal epithelium of rats, and is suspected to be a human carcinogen."1.30Significance of formaldehyde-induced DNA-protein crosslinks for mutagenesis. ( Merk, O; Speit, G, 1998)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (11.11)18.2507
2000's5 (27.78)29.6817
2010's11 (61.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, Y2
Yu, D1
Xiao, S1
Souza, AD1
Devi, R1
She, Y1
Li, Y1
Asai, G1
Sun, S1
He, J1
Pan, Z1
Cui, Y1
Ji, Z1
Li, X1
Fromowitz, M1
Mutter-Rottmayer, E1
Tung, J1
Smith, MT1
Zhang, L1
Ladeira, C3
Pádua, M1
Veiga, L1
Viegas, S2
Carolino, E2
Gomes, MC2
Brito, M2
Neuss, S2
Zeller, J2
Ma-Hock, L2
Speit, G8
Schütz, P4
Weber, I1
Kaufmann, W1
Gelbke, HP1
Durrer, S1
Mueller, JU1
Kühner, S2
Holzmann, K1
Högel, J2
Klingmann, C1
Bruckner, T1
Triebig, G1
Linsenmeyer, R2
Schmid, O1
Iarmarcovai, G1
Bonassi, S1
Sari-Minodier, I1
Baciuchka-Palmaro, M1
Botta, A1
Orsière, T1
Merk, O2
Burgaz, S1
Cakmak, G1
Erdem, O1
Yilmaz, M1
Karakaya, AE1
Pfuhler, S1
Wolf, HU1
Ballarin, C1
Sarto, F1
Giacomelli, L1
Bartolucci, GB1
Clonfero, E1

Reviews

1 review available for formaldehyde and Chromosome-Defective Micronuclei

ArticleYear
Local genotoxic effects of formaldehyde in humans measured by the micronucleus test with exfoliated epithelial cells.
    Mutation research, 2006, Volume: 613, Issue:1

    Topics: Epithelial Cells; Formaldehyde; Humans; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutag

2006

Trials

1 trial available for formaldehyde and Chromosome-Defective Micronuclei

ArticleYear
Assessment of genotoxic effects and changes in gene expression in humans exposed to formaldehyde by inhalation under controlled conditions.
    Mutagenesis, 2011, Volume: 26, Issue:4

    Topics: Biopsy; Comet Assay; Formaldehyde; Gene Expression Profiling; Gene Expression Regulation; Humans; In

2011

Other Studies

16 other studies available for formaldehyde and Chromosome-Defective Micronuclei

ArticleYear
Effects of chronic exposure to Formaldehyde on micronucleus rate of bone marrow cells in male mice.
    JPMA. The Journal of the Pakistan Medical Association, 2017, Volume: 67, Issue:6

    Topics: Animals; Bone Marrow Cells; Disinfectants; Formaldehyde; Male; Mice; Micronuclei, Chromosome-Defecti

2017
Cytokinesis blocked micronucleus assay of peripheral lymphocytes revealing the genotoxic effect of formaldehyde exposure.
    Clinical anatomy (New York, N.Y.), 2014, Volume: 27, Issue:3

    Topics: Adolescent; Adult; Anatomy; Case-Control Studies; Cytokinesis; Fixatives; Formaldehyde; Humans; Lymp

2014
Formaldehyde induces toxic effects and regulates the expression of damage response genes in BM-MSCs.
    Acta biochimica et biophysica Sinica, 2013, Volume: 45, Issue:12

    Topics: Animals; BRCA2 Protein; Cell Cycle Proteins; Cell Survival; Cells, Cultured; Checkpoint Kinase 1; Co

2013
Formaldehyde induces micronuclei in mouse erythropoietic cells and suppresses the expansion of human erythroid progenitor cells.
    Toxicology letters, 2014, Jan-13, Volume: 224, Issue:2

    Topics: Animals; Cell Cycle; Cells, Cultured; Chromosome Aberrations; Dose-Response Relationship, Drug; Eryt

2014
Influence of Serum Levels of Vitamins A, D, and E as well as Vitamin D Receptor Polymorphisms on Micronucleus Frequencies and Other Biomarkers of Genotoxicity in Workers Exposed to Formaldehyde.
    Journal of nutrigenetics and nutrigenomics, 2015, Volume: 8, Issue:4-6

    Topics: Adult; Biomarkers; Female; Formaldehyde; Humans; Male; Micronuclei, Chromosome-Defective; Micronucle

2015
Inhalation of formaldehyde does not induce genotoxic effects in broncho-alveolar lavage (BAL) cells of rats.
    Mutation research, 2010, Volume: 695, Issue:1-2

    Topics: Administration, Inhalation; Animals; Bronchoalveolar Lavage; Comet Assay; Disinfectants; DNA Damage;

2010
Analysis of micronuclei, histopathological changes and cell proliferation in nasal epithelium cells of rats after exposure to formaldehyde by inhalation.
    Mutation research, 2011, Apr-03, Volume: 721, Issue:2

    Topics: Administration, Inhalation; Animals; Cell Proliferation; Dose-Response Relationship, Drug; Formaldeh

2011
Does formaldehyde induce aneuploidy?
    Mutagenesis, 2011, Volume: 26, Issue:6

    Topics: Aneuploidy; Animals; Bromodeoxyuridine; Cell Line; Cricetinae; Demecolcine; Formaldehyde; Humans; In

2011
Re-evaluation of a reported increased micronucleus frequency in lymphocytes of workers occupationally exposed to formaldehyde.
    Mutation research, 2012, May-15, Volume: 744, Issue:2

    Topics: DNA Damage; Evaluation Studies as Topic; Formaldehyde; Humans; Lymphocytes; Micronuclei, Chromosome-

2012
The influence of genetic polymorphisms in XRCC3 and ADH5 genes on the frequency of genotoxicity biomarkers in workers exposed to formaldehyde.
    Environmental and molecular mutagenesis, 2013, Volume: 54, Issue:3

    Topics: Adult; Aldehyde Oxidoreductases; Biomarkers; DNA Repair; DNA-Binding Proteins; Environmental Monitor

2013
Exposure to genotoxic agents, host factors, and lifestyle influence the number of centromeric signals in micronuclei: a pooled re-analysis.
    Mutation research, 2007, Feb-03, Volume: 615, Issue:1-2

    Topics: Case-Control Studies; Centromere; Environmental Monitoring; Female; Formaldehyde; Genomic Instabilit

2007
Significance of formaldehyde-induced DNA-protein crosslinks for mutagenesis.
    Environmental and molecular mutagenesis, 1998, Volume: 32, Issue:3

    Topics: Animals; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Cross-Linking Reagents; DNA; For

1998
Induction and repair of formaldehyde-induced DNA-protein crosslinks in repair-deficient human cell lines.
    Mutagenesis, 2000, Volume: 15, Issue:1

    Topics: Cell Line; Cross-Linking Reagents; DNA; DNA Repair; Fanconi Anemia; Formaldehyde; Humans; Micronucle

2000
Micronuclei frequencies in exfoliated nasal mucosa cells from pathology and anatomy laboratory workers exposed to formaldehyde.
    Neoplasma, 2001, Volume: 48, Issue:2

    Topics: Adult; Anatomy; Faculty; Female; Formaldehyde; Humans; Male; Medical Laboratory Personnel; Micronucl

2001
Effects of the formaldehyde releasing preservatives dimethylol urea and diazolidinyl urea in several short-term genotoxicity tests.
    Mutation research, 2002, Feb-15, Volume: 514, Issue:1-2

    Topics: Animals; Anti-Infective Agents, Local; Cricetinae; Cross-Linking Reagents; Culture Media, Serum-Free

2002
Micronucleated cells in nasal mucosa of formaldehyde-exposed workers.
    Mutation research, 1992, Volume: 280, Issue:1

    Topics: Adult; Female; Formaldehyde; Humans; Male; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mi

1992