formaldehyde has been researched along with Carcinoma, Hepatocellular in 38 studies
paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The multi-kinase inhibitor sorafenib is now used as standard therapy for advanced hepatocellular carcinoma (HCC)." | 7.81 | Targeted DNA and RNA sequencing of fine-needle biopsy FFPE specimens in patients with unresectable hepatocellular carcinoma treated with sorafenib. ( Izumi, N; Joko, K; Nishijima, N; Nishio, K; Orito, E; Osaki, Y; Sakai, K; Takeda, H; Uchida, Y, 2015) |
| "The multi-kinase inhibitor sorafenib is now used as standard therapy for advanced hepatocellular carcinoma (HCC)." | 3.81 | Targeted DNA and RNA sequencing of fine-needle biopsy FFPE specimens in patients with unresectable hepatocellular carcinoma treated with sorafenib. ( Izumi, N; Joko, K; Nishijima, N; Nishio, K; Orito, E; Osaki, Y; Sakai, K; Takeda, H; Uchida, Y, 2015) |
| "We analyzed primary hepatocellular carcinoma (n = 10) and metastatic gastrointestinal tumors (n = 28) for phosphoprotein IHC markers pAKT, pERK, pSRC, pSTAT3, and pSMAD2 and compared them to slides obtained from the clinical blocks." | 1.56 | Effect of immediate cold formalin fixation on phosphoprotein IHC tumor biomarker signal in liver tumors using a cold transport device. ( Baird, GS; Chafin, D; Kenerson, HL; Lerch, ML; Otter, M; Theiss, A; Westerhoff, M; Yeung, RS, 2020) |
| "We analyzed peptides prepared from FFPE hepatocellular carcinoma (HCC) tissue samples by the accelerated PCT method using multiple MS acquisition methods, including short-gradient SWATH-MS, PulseDIA-MS, and 10-plex TMT-based shotgun MS." | 1.56 | Accelerated Lysis and Proteolytic Digestion of Biopsy-Level Fresh-Frozen and FFPE Tissue Samples Using Pressure Cycling Technology. ( Chen, C; Gao, H; Ge, W; Guo, T; Liang, S; Liu, K; Liu, W; Lu, C; Lyu, M; Qian, L; Sun, P; Yi, X; Zhang, F; Zhang, Q; Zhu, J; Zhu, Y, 2020) |
| "Multiple formalin-fixed human hepatocellular carcinoma tissues were evaluated with this method, resulting in a panel of over 30 N-glycans detected." | 1.42 | Two-Dimensional N-Glycan Distribution Mapping of Hepatocellular Carcinoma Tissues by MALDI-Imaging Mass Spectrometry. ( Drake, RR; Holst, S; Mehta, AS; Powers, TW; Wuhrer, M, 2015) |
| "MiR-221 is over-expressed in human hepatocellular carcinoma (HCC), but its clinical significance and function in HCC remains uncertain." | 1.39 | Increased miR-221 expression in hepatocellular carcinoma tissues and its role in enhancing cell growth and inhibiting apoptosis in vitro. ( Chen, G; Dang, Y; Rong, M, 2013) |
| "Treatment of hepatocellular carcinoma (HCC) with autologous formalin-fixed tumor vaccine after primary resection has been shown to suppress the recurrence of hepatitis B virus-associated HCC, but the effect of this treatment on hepatitis C virus (HCV)-related disease has not yet been clarified." | 1.38 | Autologous formalin-fixed tumor vaccine suppressed re-recurrence of HCV-related hepatocellular carcinoma following 29 unsuccessful treatments with extensive conventional therapy: a case report. ( Inui, T; Ohno, T, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (31.58) | 18.7374 |
| 1990's | 6 (15.79) | 18.2507 |
| 2000's | 6 (15.79) | 29.6817 |
| 2010's | 11 (28.95) | 24.3611 |
| 2020's | 3 (7.89) | 2.80 |
| Authors | Studies |
|---|---|
| Nakajima, T | 1 |
| Kagawa, K | 1 |
| Ueda, K | 1 |
| Ohkawara, T | 1 |
| Kimura, H | 1 |
| Kakusui, M | 1 |
| Deguchi, T | 1 |
| Okanoue, T | 1 |
| Kashima, K | 1 |
| Ashihara, T | 1 |
| Lerch, ML | 1 |
| Kenerson, HL | 1 |
| Chafin, D | 1 |
| Westerhoff, M | 1 |
| Theiss, A | 1 |
| Otter, M | 1 |
| Yeung, RS | 1 |
| Baird, GS | 1 |
| Gao, H | 1 |
| Zhang, F | 1 |
| Liang, S | 1 |
| Zhang, Q | 1 |
| Lyu, M | 1 |
| Qian, L | 1 |
| Liu, W | 1 |
| Ge, W | 1 |
| Chen, C | 1 |
| Yi, X | 1 |
| Zhu, J | 1 |
| Lu, C | 1 |
| Sun, P | 1 |
| Liu, K | 1 |
| Zhu, Y | 1 |
| Guo, T | 1 |
| Buczak, K | 1 |
| Kirkpatrick, JM | 1 |
| Truckenmueller, F | 1 |
| Santinha, D | 1 |
| Ferreira, L | 1 |
| Roessler, S | 1 |
| Singer, S | 1 |
| Beck, M | 1 |
| Ori, A | 1 |
| Paradiso, V | 1 |
| Garofoli, A | 1 |
| Tosti, N | 1 |
| Lanzafame, M | 1 |
| Perrina, V | 1 |
| Quagliata, L | 1 |
| Matter, MS | 1 |
| Wieland, S | 1 |
| Heim, MH | 1 |
| Piscuoglio, S | 1 |
| Ng, CKY | 1 |
| Terracciano, LM | 1 |
| Rabelo-Gonçalves, E | 1 |
| Roesler, B | 1 |
| Guardia, AC | 1 |
| Milan, A | 1 |
| Hara, N | 1 |
| Escanhoela, C | 1 |
| Almeida, J | 1 |
| Boin, I | 1 |
| Zeitune, JM | 2 |
| Kojima, K | 1 |
| April, C | 1 |
| Canasto-Chibuque, C | 1 |
| Chen, X | 1 |
| Deshmukh, M | 1 |
| Venkatesh, A | 1 |
| Tan, PS | 1 |
| Kobayashi, M | 1 |
| Kumada, H | 1 |
| Fan, JB | 1 |
| Hoshida, Y | 1 |
| Powers, TW | 2 |
| Neely, BA | 1 |
| Shao, Y | 1 |
| Tang, H | 1 |
| Troyer, DA | 1 |
| Mehta, AS | 2 |
| Haab, BB | 1 |
| Drake, RR | 2 |
| Sakai, K | 1 |
| Takeda, H | 1 |
| Nishijima, N | 1 |
| Orito, E | 1 |
| Joko, K | 1 |
| Uchida, Y | 1 |
| Izumi, N | 1 |
| Nishio, K | 1 |
| Osaki, Y | 1 |
| Holst, S | 1 |
| Wuhrer, M | 1 |
| Nakayama, Y | 1 |
| Yamaguchi, H | 1 |
| Einaga, N | 1 |
| Esumi, M | 1 |
| Inui, T | 1 |
| Ohno, T | 2 |
| Cotoi, CG | 1 |
| Khorsandi, SE | 1 |
| Pleşea, IE | 1 |
| Quaglia, A | 1 |
| Rong, M | 1 |
| Chen, G | 1 |
| Dang, Y | 1 |
| Rabelo-Gonçalves, EM | 1 |
| Sgardioli, IC | 1 |
| Lopes-Cendes, I | 1 |
| Escanhoela, CA | 1 |
| Almeida, JR | 1 |
| Williams, SS | 1 |
| Zimmerman, RL | 1 |
| Bibbo, M | 1 |
| MAISIN, JH | 1 |
| BIELKA, H | 2 |
| SCHNEIDERS, I | 2 |
| HENSKE, A | 2 |
| Kuang, M | 1 |
| Peng, BG | 1 |
| Lu, MD | 1 |
| Liang, LJ | 1 |
| Huang, JF | 1 |
| He, Q | 1 |
| Hua, YP | 1 |
| Totsuka, S | 1 |
| Liu, SQ | 1 |
| Leong, KW | 1 |
| Sjöholm, MI | 1 |
| Hoffmann, G | 1 |
| Lindgren, S | 1 |
| Dillner, J | 1 |
| Carlson, J | 1 |
| Qiu, G | 1 |
| Fang, J | 1 |
| He, Y | 1 |
| Marcsek, ZL | 1 |
| Kocsis, Z | 1 |
| Szende, B | 1 |
| Tompa, A | 1 |
| Varnholt, H | 1 |
| Drebber, U | 1 |
| Schulze, F | 1 |
| Wedemeyer, I | 1 |
| Schirmacher, P | 1 |
| Dienes, HP | 1 |
| Odenthal, M | 1 |
| Edamoto, Y | 1 |
| Tani, M | 1 |
| Kurata, T | 1 |
| Abe, K | 3 |
| Park, YN | 1 |
| Li, H | 1 |
| Hsuih, T | 1 |
| Thung, SN | 1 |
| Zhang, DY | 2 |
| Bjersing, L | 1 |
| Andersson, C | 1 |
| Lithner, F | 1 |
| Miyauchi, I | 1 |
| Moriyama, M | 1 |
| Kim, JR | 1 |
| Kim, SY | 1 |
| Kim, MJ | 1 |
| Kim, JH | 1 |
| Zhizhina, GP | 1 |
| Avakian, KA | 1 |
| Larsen, JK | 1 |
| Munch-Petersen, B | 1 |
| Christiansen, J | 1 |
| Jørgensen, K | 1 |
| Lo, YM | 1 |
| Mehal, WZ | 1 |
| Fleming, KA | 1 |
| Pancake, SJ | 1 |
| Hollingdale, MR | 1 |
| von Boehmer, H | 1 |
| Bayer, R | 1 |
| Sartorelli, AC | 3 |
| Agrawal, KC | 3 |
| Moore, EC | 3 |
| Booth, BA | 2 |
| Mooney, PD | 1 |
| Jackson, V | 1 |
| Chalkley, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Camrelizumab Combined With Apatinib Mesylate for Perioperative Treatment of Resectable Hepatocellular Carcinoma：a Randomized, Open-label, Parallel, Multicenter Trial[NCT04521153] | 290 participants (Anticipated) | Interventional | 2021-03-25 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for formaldehyde and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Phase II randomized trial of autologous formalin-fixed tumor vaccine for postsurgical recurrence of hepatocellular carcinoma.
Topics: Aged; Cancer Vaccines; Carcinoma, Hepatocellular; Disease-Free Survival; Female; Formaldehyde; Human | 2004 |
37 other studies available for formaldehyde and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Evaluation of hepatic proliferative activity in chronic liver diseases and hepatocellular carcinomas by proliferating cell nuclear antigen (PCNA) immunohistochemical staining of methanol-fixed tissues.
Topics: Analysis of Variance; Carcinoma, Hepatocellular; Cell Division; Chronic Disease; Fixatives; Formalde | 1994 |
Effect of immediate cold formalin fixation on phosphoprotein IHC tumor biomarker signal in liver tumors using a cold transport device.
Topics: Biomarkers, Tumor; Carcinoma, Hepatocellular; Cryopreservation; Formaldehyde; Humans; Immunohistoche | 2020 |
Accelerated Lysis and Proteolytic Digestion of Biopsy-Level Fresh-Frozen and FFPE Tissue Samples Using Pressure Cycling Technology.
Topics: Biopsy; Carcinoma, Hepatocellular; Digestion; DNA-Binding Proteins; Formaldehyde; High Mobility Grou | 2020 |
Spatially resolved analysis of FFPE tissue proteomes by quantitative mass spectrometry.
Topics: Carcinoma, Hepatocellular; Formaldehyde; Humans; Liver Neoplasms; Mass Spectrometry; Paraffin Embedd | 2020 |
Diagnostic Targeted Sequencing Panel for Hepatocellular Carcinoma Genomic Screening.
Topics: Biopsy; Carcinoma, Hepatocellular; DNA Copy Number Variations; DNA, Neoplasm; Exome Sequencing; Form | 2018 |
Evaluation of five DNA extraction methods for detection of H. pylori in formalin-fixed paraffin-embedded (FFPE) liver tissue from patients with hepatocellular carcinoma.
Topics: Carcinoma, Hepatocellular; DNA, Bacterial; Female; Fixatives; Formaldehyde; Helicobacter Infections; | 2014 |
Transcriptome profiling of archived sectioned formalin-fixed paraffin-embedded (AS-FFPE) tissue for disease classification.
Topics: Carcinoma, Hepatocellular; Fixatives; Formaldehyde; Gene Expression Profiling; Humans; Liver Cirrhos | 2014 |
MALDI imaging mass spectrometry profiling of N-glycans in formalin-fixed paraffin embedded clinical tissue blocks and tissue microarrays.
Topics: Adult; Animals; Carbohydrate Sequence; Carcinoma, Hepatocellular; Female; Formaldehyde; Humans; Hydr | 2014 |
Targeted DNA and RNA sequencing of fine-needle biopsy FFPE specimens in patients with unresectable hepatocellular carcinoma treated with sorafenib.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; beta Catenin; Biomarkers; Biomarkers, Tumor; Biopsy, | 2015 |
Two-Dimensional N-Glycan Distribution Mapping of Hepatocellular Carcinoma Tissues by MALDI-Imaging Mass Spectrometry.
Topics: Carcinoma, Hepatocellular; Formaldehyde; Glycosylation; Humans; Liver Neoplasms; Polysaccharides; Sp | 2015 |
Pitfalls of DNA Quantification Using DNA-Binding Fluorescent Dyes and Suggested Solutions.
Topics: Animals; Benzothiazoles; Carcinoma, Hepatocellular; Diamines; DNA; Fixatives; Fluorescent Dyes; Form | 2016 |
Autologous formalin-fixed tumor vaccine suppressed re-recurrence of HCV-related hepatocellular carcinoma following 29 unsuccessful treatments with extensive conventional therapy: a case report.
Topics: Adult; Cancer Vaccines; Carcinoma, Hepatocellular; Fixatives; Formaldehyde; Hepacivirus; Hepatectomy | 2012 |
Whole-genome DASL gene expression profiling of hepatocellular carcinoma sub-populations isolated by laser microdissection on formalin-fixed and paraffin-embedded liver tissue samples.
Topics: Carcinoma, Hepatocellular; Formaldehyde; Gene Expression Profiling; Humans; Laser Capture Microdisse | 2012 |
Increased miR-221 expression in hepatocellular carcinoma tissues and its role in enhancing cell growth and inhibiting apoptosis in vitro.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Apoptosis; Carcinoma, Hepatocellular; Caspase | 2013 |
Improved detection of Helicobacter pylori DNA in formalin-fixed paraffin-embedded (FFPE) tissue of patients with hepatocellular carcinoma using laser capture microdissection (LCM).
Topics: Carcinoma, Hepatocellular; DNA, Bacterial; Formaldehyde; Helicobacter Infections; Helicobacter pylor | 2013 |
BCA-225 immunostain: is it of value in liver fine needle aspiration?
Topics: Adenocarcinoma; Biomarkers, Tumor; Biopsy, Needle; Carcinoma, Hepatocellular; Carcinoma, Neuroendocr | 2002 |
TWO DIFFERENT ASPECTS OF THE RAT LIVER CANCERIZATION BY DAB.
Topics: Carcinogens; Carcinoma, Hepatocellular; Formaldehyde; Liver; Liver Cirrhosis; Liver Neoplasms; Micro | 1964 |
[STUDIES ON THE STRUCTURE OF RIBOSOMAL RNA FROM NORMAL AND TUMOR TISSUES. I. THERMAL DENATURATION, REACTION WITH FORMALDEHYDE AND BASE COMPOSITION].
Topics: Base Composition; Carcinoma, Hepatocellular; Chemistry Techniques, Analytical; Formaldehyde; Liver; | 1964 |
[OPTICAL BEHAVIOR OF DESOXYRIBONUCLEIC ACID FROM THE LIVER AND HEPATOMAS IN THERMAL DENATURATION AND IN THE FORMALDEHYDE REACTION].
Topics: Carcinoma, Hepatocellular; DNA; DNA, Neoplasm; Formaldehyde; Liver; Liver Neoplasms; Neoplasm Transp | 1964 |
Comparison of archival plasma and formalin-fixed paraffin-embedded tissue for genotyping in hepatocellular carcinoma.
Topics: Carcinoma, Hepatocellular; Formaldehyde; Genotype; Humans; Liver Neoplasms; Nucleic Acid Amplificati | 2005 |
5' CpG island methylation analysis identifies the MAGE-A1 and MAGE-A3 genes as potential markers of HCC.
Topics: Adult; Aged; Antigens, Neoplasm; Biomarkers, Tumor; Carcinoma, Hepatocellular; Case-Control Studies; | 2006 |
Effect of formaldehyde and resveratrol on the viability of Vero, HepG2 and MCF-7 cells.
Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Breast Neoplasms; Carcino | 2007 |
MicroRNA gene expression profile of hepatitis C virus-associated hepatocellular carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Female; Formal | 2008 |
Hepatitis C and B virus infections in hepatocellular carcinoma. Analysis of direct detection of viral genome in paraffin embedded tissues.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; DNA, Viral; Female; Fixatives; Formaldehy | 1996 |
Detection of hepatitis C virus RNA using ligation-dependent polymerase chain reaction in formalin-fixed, paraffin-embedded liver tissues.
Topics: Base Sequence; Carcinoma, Hepatocellular; Fixatives; Formaldehyde; Hepacivirus; Humans; Liver; Liver | 1996 |
Hepatocellular carcinoma in patients from northern Sweden with acute intermittent porphyria: morphology and mutations.
Topics: Adenine; Aged; Aged, 80 and over; Alleles; Base Sequence; Carcinoma, Hepatocellular; Cell Division; | 1996 |
Further study of hepatitis C virus RNA detection in formalin-fixed, paraffin-embedded liver tissues by ligation-dependent polymerase chain reaction.
Topics: Adult; Aged; Base Sequence; Carcinoma, Hepatocellular; DNA Primers; DNA Probes; Formaldehyde; Hepaci | 1998 |
Alterations of CDKN2 (MTS1/p16INK4A) gene in paraffin-embedded tumor tissues of human stomach, lung, cervix and liver cancers.
Topics: Adenocarcinoma; Carcinoma, Hepatocellular; Cyclin-Dependent Kinase Inhibitor p16; Female; Formaldehy | 1998 |
[Effect of endonuclease S1 on the DNA of normal and tumor cells].
Topics: Animals; Aspergillus oryzae; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Densitometry; DNA; | 1979 |
Flow cytometric discrimination of mitotic cells: resolution of M, as well as G1, S, and G2 phase nuclei with mithramycin, propidium iodide, and ethidium bromide after fixation with formaldehyde.
Topics: Animals; Carcinoma, Hepatocellular; Detergents; Ethidium; Fixatives; Flow Cytometry; Fluorescent Dye | 1986 |
In vitro amplification of hepatitis B virus sequences from liver tumour DNA and from paraffin wax embedded tissues using the polymerase chain reaction.
Topics: Base Sequence; Carcinoma; Carcinoma, Hepatocellular; DNA, Neoplasm; DNA, Viral; Fixatives; Formaldeh | 1989 |
Plasmodium berghei: reaction of sporozoites with chemically and enzymatically modified hepatoma cells.
Topics: Carcinoma, Hepatocellular; Cells, Cultured; Chymotrypsin; Formaldehyde; Galactose Oxidase; Glutaral; | 1986 |
[Experiments on rats for finding out the immune response to a Yoshida hepatoma ascites transplant].
Topics: Animals; Antibody Formation; Ascites; Carcinoma, Hepatocellular; Complement System Proteins; Cytotox | 1972 |
Mechanism of inhibition of ribonucleoside diphosphate reductase by a-(N)-heterocyclic aldehyde thiosemicarbazones.
Topics: Animals; Binding Sites; Carcinoma, Hepatocellular; Cytosine Nucleotides; DNA, Neoplasm; Formaldehyde | 1971 |
Alpha-(N)-heterocyclic carboxaldehyde thiosemicarbazone inhibitors of ribonucleoside diphosphate reductase.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cytidine; Deoxyribonucleotides; DNA, Neop | 1974 |
Potential antitumor agents. 10. Synthesis and biochemical properties of 5-N-alkylamino-,N,N-dialkylamino-, and N-alkylacetamido-1-formylisoquinoline thiosemicarbazones.
Topics: Animals; Antineoplastic Agents; Binding Sites; Carcinoma, Hepatocellular; Depression, Chemical; DNA, | 1974 |
Separation of newly synthesized nucleohistone by equilibrium centrifugation in cesium chloride.
Topics: Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; Cesi | 1974 |