Page last updated: 2024-10-18

formaldehyde and Carcinogenesis

formaldehyde has been researched along with Carcinogenesis in 14 studies

paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy

Carcinogenesis: The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.

Research Excerpts

ExcerptRelevanceReference
" Our study aimed at assessing the effect of formaldehyde on lipid peroxidation and verifying the susceptibility to carcinogenesis using p53 as a biomarker among workers exposed to formaldehyde in cosmetic industry."7.83Assessment of lipid peroxidation and p53 as a biomarker of carcinogenesis among workers exposed to formaldehyde in the cosmetic industry. ( Attia, D; Mansour, N; Seif El Dein, A; Taha, F, 2016)
" Group I served as control (not subjected to any kind of treatment), and groups II and III were subjected to two-stage chemical carcinogenesis through topical application of dimethylbenz[a]anthracene (DMBA) followed by formaldehyde on dorsal and ventral surfaces of tongues for 9 weeks."7.80Chemopreventive effect of Mentha piperita on dimethylbenz[a]anthracene and formaldehyde-induced tongue carcinogenesis in mice (histological and immunohistochemical study). ( AbdelMohsen, MM; Arafa, MA; Hegazy, RH; Kasem, RF, 2014)
" Our study aimed at assessing the effect of formaldehyde on lipid peroxidation and verifying the susceptibility to carcinogenesis using p53 as a biomarker among workers exposed to formaldehyde in cosmetic industry."3.83Assessment of lipid peroxidation and p53 as a biomarker of carcinogenesis among workers exposed to formaldehyde in the cosmetic industry. ( Attia, D; Mansour, N; Seif El Dein, A; Taha, F, 2016)
" Group I served as control (not subjected to any kind of treatment), and groups II and III were subjected to two-stage chemical carcinogenesis through topical application of dimethylbenz[a]anthracene (DMBA) followed by formaldehyde on dorsal and ventral surfaces of tongues for 9 weeks."3.80Chemopreventive effect of Mentha piperita on dimethylbenz[a]anthracene and formaldehyde-induced tongue carcinogenesis in mice (histological and immunohistochemical study). ( AbdelMohsen, MM; Arafa, MA; Hegazy, RH; Kasem, RF, 2014)
"Carcinogenesis is a complex process initiated by a mutation in DNA that may be caused by chemical carcinogens present in polluted environments and human diet."3.01Electrochemical and Optical Sensors for the Detection of Chemical Carcinogens Causing Leukemia. ( Kowalczyk, A; Lejman, M; Zarychta, J; Zawitkowska, J, 2023)
"Assessing the shape of dose-response curves for DNA-damage in cellular systems and for the consequences of DNA damage in intact animals remains a controversial topic."2.53Approaches for characterizing threshold dose-response relationships for DNA-damage pathways involved in carcinogenicity in vivo and micronuclei formation in vitro. ( Andersen, ME; Clewell, RA, 2016)
"Despite progress in treatment of small cell lung cancer (SCLC), its multidrug chemoresistance and poor prognosis still remain."1.48Long non-coding RNA HOTTIP promotes BCL-2 expression and induces chemoresistance in small cell lung cancer by sponging miR-216a. ( Guo, L; Guo, Y; Hu, B; Qiu, Q; Sun, Y; Wang, Q; Ye, M; Zeng, F; Zhang, X; Zhou, Y, 2018)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (57.14)24.3611
2020's5 (35.71)2.80

Authors

AuthorsStudies
Balasubramaniam, SD1
Balakrishnan, V1
Oon, CE1
Kaur, G1
Khoshakhlagh, AH1
Chuang, KJ1
Kumar, P1
Kim, S1
Koh, J1
Song, SG1
Yim, J1
Kim, M1
Keam, B1
Kim, YT1
Kim, J1
Chung, DH1
Jeon, YK1
Dator, RP1
Murray, KJ1
Luedtke, MW1
Jacobs, FC1
Kassie, F1
Nguyen, HD1
Villalta, PW1
Balbo, S1
Kowalczyk, A1
Zarychta, J1
Lejman, M1
Zawitkowska, J1
Rothman, N1
Lan, Q1
Smith, MT1
Vermeulen, R1
Zhang, L1
Sun, Y1
Hu, B1
Wang, Q1
Ye, M1
Qiu, Q1
Zhou, Y1
Zeng, F1
Zhang, X1
Guo, Y1
Guo, L1
Kim, EM1
Lee, HY1
Lee, EH1
Lee, KM1
Park, M1
Ji, KY1
Jang, JH1
Jeong, YH1
Lee, KH1
Yoon, IJ1
Kim, SM1
Jeong, MJ1
Kim, KD1
Kang, HS1
Lee, TS1
Jeon, HW1
Kim, YB1
Kim, YA1
Kim, MA1
Kang, SB1
Kasem, RF1
Hegazy, RH1
Arafa, MA1
AbdelMohsen, MM1
Attia, D1
Mansour, N1
Taha, F1
Seif El Dein, A1
Rhomberg, LR1
Clewell, RA1
Andersen, ME1
HORTON, AW1
TYE, R1
STEMMER, KL1

Reviews

2 reviews available for formaldehyde and Carcinogenesis

ArticleYear
Electrochemical and Optical Sensors for the Detection of Chemical Carcinogens Causing Leukemia.
    Sensors (Basel, Switzerland), 2023, Mar-23, Volume: 23, Issue:7

    Topics: Carcinogenesis; Carcinogens; Formaldehyde; Humans; Leukemia; Neoplasms

2023
Approaches for characterizing threshold dose-response relationships for DNA-damage pathways involved in carcinogenicity in vivo and micronuclei formation in vitro.
    Mutagenesis, 2016, Volume: 31, Issue:3

    Topics: Animals; Carcinogenesis; Cell Line; Computational Biology; DNA; DNA Damage; DNA Repair; Dose-Respons

2016

Other Studies

12 other studies available for formaldehyde and Carcinogenesis

ArticleYear
Gene expression profiling of HPV-associated cervical carcinogenesis in formalin-fixed paraffin-embedded (FFPE) tissues using the NanoString nCounter
    Gene, 2022, May-30, Volume: 825

    Topics: Carcinogenesis; Carcinoma, Squamous Cell; Cervix Uteri; Female; Formaldehyde; Gene Expression Profil

2022
Health risk assessment of exposure to ambient formaldehyde in carpet manufacturing industries.
    Environmental science and pollution research international, 2023, Volume: 30, Issue:6

    Topics: Carcinogenesis; Carcinogens; Floors and Floorcoverings; Formaldehyde; Humans; Manufacturing Industry

2023
High tumor hexokinase-2 expression promotes a pro-tumorigenic immune microenvironment by modulating CD8+/regulatory T-cell infiltration.
    BMC cancer, 2022, Nov-01, Volume: 22, Issue:1

    Topics: Adenocarcinoma of Lung; B7-H1 Antigen; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Carcinoma, Sq

2022
Identification of Formaldehyde-Induced DNA-RNA Cross-Links in the A/J Mouse Lung Tumorigenesis Model.
    Chemical research in toxicology, 2022, 11-21, Volume: 35, Issue:11

    Topics: Animals; Carcinogenesis; Cell Transformation, Neoplastic; DNA; Formaldehyde; Lung; Mice; Mice, Inbre

2022
Response to letter to the editor of Carcinogenesis by Pira et al., 2017.
    Carcinogenesis, 2017, 12-07, Volume: 38, Issue:12

    Topics: Biomarkers; Carcinogenesis; Formaldehyde; Humans; Leukemia; Respiratory Hypersensitivity

2017
Long non-coding RNA HOTTIP promotes BCL-2 expression and induces chemoresistance in small cell lung cancer by sponging miR-216a.
    Cell death & disease, 2018, 01-24, Volume: 9, Issue:2

    Topics: Animals; Apoptosis; Base Sequence; Carcinogenesis; Cell Line, Tumor; Drug Resistance, Neoplasm; Fema

2018
Formaldehyde exposure impairs the function and differentiation of NK cells.
    Toxicology letters, 2013, Nov-25, Volume: 223, Issue:2

    Topics: Animals; B-Lymphocytes; Bronchoalveolar Lavage; Carcinogenesis; Cell Differentiation; Cell Survival;

2013
Aberrant microRNA expression in endometrial carcinoma using formalin-fixed paraffin-embedded (FFPE) tissues.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Carcinogenesis; Carcinoma, Endometrioid; DNA Primers; Female; Formaldehyde; Gene Expression Profilin

2013
Chemopreventive effect of Mentha piperita on dimethylbenz[a]anthracene and formaldehyde-induced tongue carcinogenesis in mice (histological and immunohistochemical study).
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2014, Volume: 43, Issue:7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antioxidants; Basement Membrane;

2014
Assessment of lipid peroxidation and p53 as a biomarker of carcinogenesis among workers exposed to formaldehyde in the cosmetic industry.
    Toxicology and industrial health, 2016, Volume: 32, Issue:6

    Topics: Adolescent; Adult; Air Pollutants, Occupational; Alkaline Phosphatase; Bilirubin; Biomarkers; Carcin

2016
Contrasting directions and directives on hazard identification for formaldehyde carcinogenicity.
    Regulatory toxicology and pharmacology : RTP, 2015, Volume: 73, Issue:3

    Topics: Animals; Carcinogenesis; Carcinogenicity Tests; Fixatives; Formaldehyde; Humans; Neoplasms; Risk Ass

2015
Experimental carcinogenesis of the lung. Inhalation of gaseous formaldehyde or an aerosol of coal tar by C3H mice.
    Journal of the National Cancer Institute, 1963, Volume: 30

    Topics: Aerosols; Animals; Carcinogenesis; Carcinogens; Carcinoma; Carcinoma, Squamous Cell; Coal Tar; Forma

1963