Page last updated: 2024-10-18

formaldehyde and Cancer of Prostate

formaldehyde has been researched along with Cancer of Prostate in 110 studies

paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy

Research Excerpts

ExcerptRelevanceReference
" Accumulated evidence shows that endogenous formaldehyde concentrations are elevated in the blood or urine of patients with breast, prostate or bladder cancer."7.76Tumor tissue-derived formaldehyde and acidic microenvironment synergistically induce bone cancer pain. ( Duan, B; Han, Y; Li, H; Liu, F; Luo, H; Luo, W; Maoying, Q; Tan, H; Tong, Z; Wan, Y; Wang, J; Wang, Y; Xu, T; Yang, F; Zhao, H, 2010)
" Accumulated evidence shows that endogenous formaldehyde concentrations are elevated in the blood or urine of patients with breast, prostate or bladder cancer."3.76Tumor tissue-derived formaldehyde and acidic microenvironment synergistically induce bone cancer pain. ( Duan, B; Han, Y; Li, H; Liu, F; Luo, H; Luo, W; Maoying, Q; Tan, H; Tong, Z; Wan, Y; Wang, J; Wang, Y; Xu, T; Yang, F; Zhao, H, 2010)
"The contemporary problem of prostate cancer overtreatment can be partially attributed to the diagnosis of potentially indolent prostate cancers that pose low risk to aged men, and lack of sufficiently accurate risk stratification methods to reliably seek out men with indolent diseases."2.48Molecular profiling of indolent human prostate cancer: tackling technical challenges to achieve high-fidelity genome-wide data. ( De Marzo, AM; Dunn, TA; Fedor, HL; Luo, J, 2012)
"A number of bladder cancer case-control studies have noted an association with work as a machinist."2.40Oils and cancer. ( Tolbert, PE, 1997)
"Prostate cancer is the most common cancer in males worldwide."1.72A prostate cancer tissue specific spectral library for targeted proteomic analysis. ( Chen, L; Chen, S; Ding, X; Ge, W; Guo, T; Liang, S; Lyu, M; Sun, R; Wang, Y; Zhang, C; Zhou, Y, 2022)
"Malignant regions within prostate cancer samples more frequently contained cells with low Complex I & IV and high mitochondrial mass in comparison to benign-adjacent regions."1.72Automated quantitative high-throughput multiplex immunofluorescence pipeline to evaluate OXPHOS defects in formalin-fixed human prostate tissue. ( Brown, MD; Carey, CD; Clarke, NW; Greaves, LC; Hart, CA; Heer, R; Oliveira, P; Sachdeva, A; Turnbull, DM; Vincent, AE, 2022)
"From 63 prostate cancers examined, 59(94%) of the samples yielded at least 30 ng of DNA, the minimum amount of DNA considered suitable for NGS analysis."1.42Mutation detection in formalin-fixed prostate cancer biopsies taken at the time of diagnosis using next-generation DNA sequencing. ( Anderson, E; Ball, R; Brewer, DS; Clark, J; Cooper, C; Curley, H; Flather, M; Goody, V; Gundem, G; Hurst, R; Keeling, M; Manson-Bahr, D; McDermott, U; Mills, R; O'Meara, S; Rochester, M; Sethia, K; Yazbek-Hanna, M, 2015)
"The probability of prostate cancer detection is related to the amount of tissue represented."1.42Prostate Biopsy Core Handling: Comparison of Contemporary Preembedding Methods. ( Dellmann, A; Donhuijsen, K; Hammerer, PG; Pryalukhin, AE; Vandromme, A, 2015)
"We used two cell lines, DU145 (prostate cancer) and SKOV3 (ovarian cancer), grew them on coverslips and fixed them with 10% NBF at room temperature for 5 min and 12, 15, 18, 36, 108 and 180 h."1.39Preservation of immunorecognition by transferring cells from 10% neutral buffered formalin to 70% ethanol. ( Grizzle, WE; He, Q; Otali, D; Stockard, CR, 2013)
"In addition, 101 PCa patient samples, 13 benign prostatic hyperplasia (BPH) and 12 normal adjacent tissue samples, were assayed by PS and SS to evaluate their detection abilities for K-Ras mutations in codons 12 and 13."1.38Application of pyrosequencing technique for improved detection of K-Ras mutation in formalin-fixed and paraffin-embedded prostate carcinoma tissues in Chinese patients. ( Bo, J; Huang, Y; Li, D; Liang, G; Liu, D; Liu, W; Pan, J; Ping, P; Sha, J; Shen, W; Xuan, H, 2012)
"We present an example from a prostate cancer study using formalin-fixed paraffin-embedded tissue."1.37Multivariate analyses for biomarkers hunting and validation through on-tissue bottom-up or in-source decay in MALDI-MSI: application to prostate cancer. ( Bonnel, D; Day, R; Fournier, I; Franck, J; Gosset, P; Longuespee, R; Roudbaraki, M; Salzet, M, 2011)
"In the context of prostate cancer, this implies profiling in the diagnostic formalin-fixed, paraffin-embedded (FFPE) transrectal ultrasound-guided (TRUS) needle biopsy."1.37Laser-capture microdissection and transcriptional profiling in archival FFPE tissue in prostate cancer. ( Gnanapragasam, VJ; Joseph, A, 2011)
"In assessing the prevalence of XMRV in prostate cancer tissue samples we discovered that eluates from naïve DNA purification columns, when subjected to PCR with primers designed to detect genomic mouse DNA contamination, occasionally gave rise to amplification products."1.37DNA extraction columns contaminated with murine sequences. ( Dustan, S; Erlwein, O; Kaye, S; McClure, MO; Robinson, MJ; Weber, J, 2011)
"Diagnosis of prostate cancer (PCa) typically relies on needle biopsies, which are routinely archived in paraffin after formalin fixation and may contain valuable risk or prognostic information."1.36mRNA and micro-RNA expression analysis in laser-capture microdissected prostate biopsies: valuable tool for risk assessment and prevention trials. ( Gallagher, L; Gann, PH; Nonn, L; Vaishnav, A, 2010)
"This formamide-based method was applied to 46 formalin-fixed/paraffin-embedded (FFPE) biopsy tissue specimens from well-characterized patients with primary prostate cancer."1.35Formamide as a denaturant for bisulfite conversion of genomic DNA: Bisulfite sequencing of the GSTPi and RARbeta2 genes of 43 formalin-fixed paraffin-embedded prostate cancer specimens. ( Barker, MA; Boyd, VL; Groshen, S; Imam, SA; Jones, LW; Kaur, P; Zon, G, 2009)
"Identification of prostate cancer associated-gene expression alterations such as AMACR, Kallikrein gene family and genes associated with androgen signaling such as PDEF and STEAP were consistent with previous findings reported in prostate cancer."1.35Transcriptome analyses of benign and malignant prostate epithelial cells in formalin-fixed paraffin-embedded whole-mounted radical prostatectomy specimens. ( Dobi, A; Furusato, B; McLeod, DG; Nau, ME; Petrovics, G; Ravindranath, L; Seifert, M; Sesterhenn, IA; Shaheduzzaman, S; Srivastava, S; Vahey, M; Werner, T, 2008)
"We have used prostate cancer, the most commonly diagnosed noncutaneous neoplasm among men, to investigate the feasibility of performing genomic array analyses of archival tissue."1.32High-resolution analysis of paraffin-embedded and formalin-fixed prostate tumors using comparative genomic hybridization to genomic microarrays. ( Albertson, DG; Alers, JC; Andaya, A; Carroll, P; Collins, C; Fridlyand, J; Jain, AN; Kamkar, S; Kowbel, D; Krijtenburg, PJ; Paris, PL; Pinkel, D; Schröder, FH; Van Dekken, H; Vissers, KJ; Watson, VJ; Wildhagen, MF, 2003)
"The pain was treated with lidocaine ointment and sitz baths with partial success."1.31Complications following formalin installation in the treatment of radiation induced proctitis. ( Belin, B; Efron, J; Nogueras, JJ; Pikarsky, AJ; Weiss, EG; Wexner, SD, 2000)
"In 14 cases of moderate and high-grade prostate cancer with metastases to lymph nodes, we found 34 beta E12 positivity in 6 (43%) of 14 metastases and in 7 (54%) of 13 primary tumors."1.30Anticytokeratin antibody 34 beta E12 staining in prostate carcinoma. ( Fitzgibbon, JF; Googe, PB; McGinley, KM, 1997)
"The TP53 gene mutation pattern in prostatic cancer was examined in relation to progression and survival, using archival formalin-fixed pre- and post-treatment tumour specimens from 84 prostatic cancer patients."1.29TP53 mutations in prostatic cancer. Analysis of pre- and post-treatment archival formalin-fixed tumour tissue. ( Berner, A; Børresen, AL; Fosså, SD; Geitvik, G; Karlsen, F; Nesland, JM, 1995)
"Seven patients had had cancer of the uterine cervix, and one patient had had cancer of the prostate treated with radiotherapy at a median time of 30 months (range, 9-46 months) previously."1.29A simple and effective treatment for hemorrhagic radiation proctitis using formalin. ( Eu, KW; Goh, HS; Ho, YH; Seow-Choen, F; Tay, SK, 1993)
"Recent animal studies found nasal cancer among rats exposed to formaldehyde, but no excess of this tumor occurred in this study."1.27Mortality among industrial workers exposed to formaldehyde. ( Bales, R; Blair, A; Cubit, D; Gaffey, W; Kaplan, S; O'Berg, M; Stewart, P; Walrath, J; Ward, J, 1986)
"All carcinomas (primary focus or metastasis) of non prostatic origin (55) stained negatively with the developed antiserum."1.26Demonstration of the prostatic origin of metastases: an immunohistochemical method for formalin-fixed embedded tissue. ( Anholt, RR; De Vries, GP; Jöbsis, AC; Sanders, GT, 1978)

Research

Studies (110)

TimeframeStudies, this research(%)All Research%
pre-199010 (9.09)18.7374
1990's16 (14.55)18.2507
2000's32 (29.09)29.6817
2010's44 (40.00)24.3611
2020's8 (7.27)2.80

Authors

AuthorsStudies
Sun, R1
Lyu, M1
Liang, S1
Ge, W1
Wang, Y2
Ding, X1
Zhang, C1
Zhou, Y1
Chen, S1
Chen, L1
Guo, T1
Sachdeva, A1
Hart, CA1
Carey, CD1
Vincent, AE1
Greaves, LC1
Heer, R1
Oliveira, P1
Brown, MD1
Clarke, NW1
Turnbull, DM1
Bozgeyik, E1
Ceylan, O1
Mantsiou, A1
Makridakis, M1
Fasoulakis, K1
Katafigiotis, I1
Constantinides, CA1
Zoidakis, J1
Roubelakis, MG1
Vlahou, A1
Lygirou, V1
Ali, F1
Hu, KY1
de Schaetzen van Brienen, L1
Larmuseau, M1
Van der Eecken, K1
De Ryck, F1
Robbe, P1
Schuh, A1
Fostier, J1
Ost, P1
Marchal, K1
Ebrahimizadeh, W1
Guérard, KP1
Rouzbeh, S1
Bramhecha, YM1
Scarlata, E1
Brimo, F1
Patel, PG1
Jamaspishvili, T1
Aprikian, AG1
Berman, D1
Bartlett, JMS1
Chevalier, S1
Lapointe, J1
Buszewska-Forajta, M1
Raczak-Gutknecht, J1
Artymowicz, M1
Wesołowski, W1
Buczkowski, K1
Iżycka-Świeszewska, E1
Markuszewski, MJ1
Nikitina, AS1
Sharova, EI1
Danilenko, SA1
Butusova, TB1
Vasiliev, AO1
Govorov, AV1
Prilepskaya, EA1
Pushkar, DY1
Kostryukova, ES1
FitzGerald, LM1
Raspin, K1
Marthick, JR1
Field, MA1
Malley, RC1
Thomson, RJ1
Blackburn, NB1
Banks, A1
Charlesworth, JC1
Donovan, S1
Dickinson, JL1
Eryilmaz, IE1
Aytac Vuruskan, B1
Kaygısız, O1
Egeli, U1
Tunca, B1
Kordan, Y1
Cecener, G1
Carlsson, J1
Davidsson, S1
Fridfeldt, J1
Giunchi, F1
Fiano, V1
Grasso, C1
Zelic, R1
Richiardi, L1
Andrén, O1
Pettersson, A1
Fiorentino, M2
Akre, O1
Hagen, RM2
Rhodes, A2
Oxley, J2
Ladomery, MR2
Samalavicius, NE1
Dulskas, A1
Kilius, A1
Petrulis, K1
Norkus, D1
Burneckis, A1
Valuckas, KP1
Yeoh, E1
Tam, W1
Schoeman, M1
Moore, J1
Thomas, M1
Botten, R1
Di Matteo, A1
Davalieva, K1
Kiprijanovska, S1
Polenakovic, M1
Miller, JK1
Buchner, N1
Timms, L1
Tam, S1
Luo, X1
Brown, AM1
Pasternack, D1
Bristow, RG1
Fraser, M1
Boutros, PC1
McPherson, JD1
Long, Q1
Xu, J2
Osunkoya, AO1
Sannigrahi, S1
Johnson, BA1
Zhou, W1
Gillespie, T1
Park, JY1
Nam, RK1
Sugar, L1
Stanimirovic, A1
Seth, AK1
Petros, JA1
Moreno, CS1
Powers, TW1
Neely, BA1
Shao, Y1
Tang, H1
Troyer, DA1
Mehta, AS1
Haab, BB1
Drake, RR1
Adamo, P1
Karamat, S1
Aning, JJ1
Gillatt, D1
Persad, R1
Manson-Bahr, D1
Ball, R1
Gundem, G1
Sethia, K1
Mills, R1
Rochester, M1
Goody, V1
Anderson, E1
O'Meara, S1
Flather, M1
Keeling, M1
Yazbek-Hanna, M1
Hurst, R1
Curley, H1
Clark, J2
Brewer, DS1
McDermott, U1
Cooper, C1
Brzezinska, EA1
Nixon, C1
Patel, R1
Leung, HY2
Grasso, CS1
Cani, AK1
Hovelson, DH1
Quist, MJ1
Douville, NJ1
Yadati, V1
Amin, AM1
Nelson, PS1
Betz, BL1
Liu, CJ1
Knudsen, KE1
Cooney, KA1
Feng, FY1
McDaniel, AS1
Tomlins, SA1
Pryalukhin, AE1
Vandromme, A1
Dellmann, A1
Donhuijsen, K1
Hammerer, PG1
Wagner, J1
Damaschke, N1
Yang, B1
Truong, M1
Guenther, C1
McCormick, J1
Huang, W1
Jarrard, D1
Tyekucheva, S1
Martin, NE1
Stack, EC1
Wei, W1
Vathipadiekal, V1
Waldron, L1
Lis, RT1
Stampfer, MJ1
Loda, M1
Parmigiani, G1
Mucci, LA1
Birrer, M1
Thompson, ML1
Jimenez-Andrade, JM1
Chartier, S1
Tsai, J1
Burton, EA1
Habets, G1
Lin, PS1
West, BL1
Mantyh, PW1
Dziki, Ł1
Kujawski, R1
Mik, M1
Berut, M1
Dziki, A1
Trzciński, R1
Reynolds, HM1
Williams, S1
Zhang, A1
Chakravorty, R1
Rawlinson, D1
Ong, CS1
Esteva, M1
Mitchell, C1
Parameswaran, B1
Finnegan, M1
Liney, G1
Haworth, A1
Mihala, A1
Alexa, AA1
Samoilă, C1
Dema, A1
Vizitiu, AC1
Anghel, A1
Tămaş, L1
Marian, CV1
Sîrbu, IO1
Peng, Z1
Andersson, K1
Lindholm, J1
Dethlefsen, O1
Pramana, S1
Pawitan, Y1
Nistér, M1
Nilsson, S1
Li, C1
Panderi, I1
Yakirevich, E1
Papagerakis, S1
Noble, L1
Lombardo, K1
Pantazatos, D1
Peskoe, SB1
Barber, JR1
Zheng, Q1
Meeker, AK1
De Marzo, AM4
Platz, EA1
Lupold, SE1
Singla, N1
Walker, J1
Woldu, SL1
Passoni, NM1
de la Fuente, K1
Roehrborn, CG1
Doak, SH1
Rogers, D1
Jones, B1
Francis, L1
Conlan, RS1
Wright, C1
Agell, L1
Hernández, S1
de Muga, S1
Lorente, JA1
Juanpere, N1
Esgueva, R1
Serrano, S1
Gelabert, A1
Lloreta, J1
Lutz, BR1
Dentinger, CE1
Nguyen, LN1
Sun, L1
Zhang, J1
Allen, AN2
Chan, S1
Knudsen, BS2
Zon, G1
Barker, MA1
Kaur, P1
Groshen, S1
Jones, LW1
Imam, SA1
Boyd, VL1
McCarthy, F2
Fletcher, A1
Dennis, N2
Cummings, C1
O'Donnell, H1
Flohr, P2
Vergis, R1
Jhavar, S2
Parker, C2
Cooper, CS2
Patel, P1
Subhas, G1
Gupta, A1
Chang, YJ1
Mittal, VK1
McKendrick, A1
Nonn, L1
Vaishnav, A1
Gallagher, L1
Gann, PH2
Otali, D2
Stockard, CR2
Oelschlager, DK1
Wan, W1
Manne, U1
Watts, SA1
Grizzle, WE2
Tong, Z1
Luo, W1
Yang, F1
Han, Y1
Li, H1
Luo, H1
Duan, B1
Xu, T1
Maoying, Q1
Tan, H1
Wang, J1
Zhao, H1
Liu, F1
Wan, Y1
Jaraj, SJ1
Egevad, L2
Bonnel, D1
Longuespee, R1
Franck, J1
Roudbaraki, M1
Gosset, P1
Day, R1
Salzet, M1
Fournier, I1
Joseph, A1
Gnanapragasam, VJ2
Erlwein, O1
Robinson, MJ1
Dustan, S1
Weber, J1
Kaye, S1
McClure, MO1
Lotan, TL1
Gurel, B1
Sutcliffe, S1
Esopi, D1
Liu, W2
Hicks, JL1
Park, BH1
Humphreys, E1
Partin, AW1
Han, M1
Netto, GJ1
Isaacs, WB1
Kerick, M1
Isau, M1
Timmermann, B1
Sültmann, H1
Herwig, R1
Krobitsch, S1
Schaefer, G1
Verdorfer, I1
Bartsch, G1
Klocker, H1
Lehrach, H1
Schweiger, MR1
Bourne, RM2
Kurniawan, N2
Cowin, G2
Stait-Gardner, T2
Sved, P2
Watson, G2
Chowdhury, S1
Price, WS2
Dunn, TA1
Fedor, HL1
Luo, J1
Al-Amin, A1
Cowley, R1
Scott, N1
Sha, J1
Liang, G1
Pan, J1
Xuan, H1
Ping, P1
Li, D1
Bo, J1
Liu, D1
Shen, W1
Huang, Y1
Ortiz-Rey, JA1
San Miguel-Fraile, P1
Gómez de María, C1
Huri de Lama, S1
Rodríguez Sánchez, MC1
Menon, R1
Deng, M1
Boehm, D2
Braun, M1
Fend, F1
Biskup, S1
Perner, S1
Beltran, H1
Yelensky, R1
Frampton, GM1
Park, K1
Downing, SR1
MacDonald, TY1
Jarosz, M1
Lipson, D1
Tagawa, ST1
Nanus, DM1
Stephens, PJ1
Mosquera, JM1
Cronin, MT1
Rubin, MA2
He, Q1
Fordyce, CA1
Heaphy, CM1
Griffith, JK1
Fedor, HH1
Gage, WR1
Paris, PL2
Albertson, DG2
Alers, JC1
Andaya, A1
Carroll, P1
Fridlyand, J1
Jain, AN1
Kamkar, S1
Kowbel, D1
Krijtenburg, PJ1
Pinkel, D2
Schröder, FH2
Vissers, KJ1
Watson, VJ1
Wildhagen, MF1
Collins, C2
Van Dekken, H2
Shi, SR1
Cote, RJ1
Liu, C1
Yu, MC1
Castelao, JE1
Ross, RK1
Taylor, CR1
Leiva, IM1
Emmert-Buck, MR1
Gillespie, JW1
DELORY, GE1
SWEETSER, TH1
WHITE, TA1
Cogan, PS1
Koch, TH1
Bibikova, M2
Yeakley, JM1
Chudin, E2
Chen, J1
Wickham, E1
Wang-Rodriguez, J2
Fan, JB2
van Duin, M1
van Marion, R1
Watson, JE1
Lapuk, A1
Brown, N1
Oseroff, VV1
de Jong, P1
Nacheva, EP1
Dinjens, W1
Konishi, T1
Watanabe, T1
Kitayama, J1
Shibahara, J1
Nagawa, H1
Ananthanarayanan, V1
Pins, MR1
Meyer, RE1
Yuyama, H1
Koakutsu, A1
Fujiyasu, N1
Fujimori, A1
Sato, S1
Shibasaki, K1
Tanaka, S1
Sudoh, K1
Sasamata, M1
Miyata, K1
Miyoshi, Y1
Uemura, H1
Ishiguro, H1
Kitamura, H1
Nomura, N1
Danenberg, PV1
Kubota, Y1
Hood, BL2
Darfler, MM1
Guiel, TG1
Furusato, B2
Lucas, DA1
Ringeisen, BR1
Sesterhenn, IA2
Conrads, TP2
Veenstra, TD2
Krizman, DB1
Hwang, SI1
Thumar, J1
Lundgren, DH1
Rezaul, K1
Mayya, V1
Wu, L1
Eng, J1
Wright, ME1
Han, DK1
Jonmarker, S1
Valdman, A1
Lindberg, A1
Hellström, M1
Arsanjani, A1
Zhou, L1
Garcia, EW1
Modder, J1
Kostelec, M1
Barker, D1
Downs, T1
Shaheduzzaman, S1
Petrovics, G1
Dobi, A1
Seifert, M1
Ravindranath, L1
Nau, ME1
Werner, T1
Vahey, M1
McLeod, DG1
Srivastava, S1
McLerran, DF1
Vessella, RL1
Karademos, J1
Davies, JE1
Maqsodi, B1
McMaster, GK1
Kristal, AR1
Rogerson, L1
Darby, S1
Jabbar, T1
Mathers, ME1
Robson, CN1
Sahadevan, K1
O'Toole, K1
Rouzier, C1
Haudebourg, J1
Carpentier, X1
Valério, L1
Amiel, J1
Michiels, JF1
Pedeutour, F1
Srivastava, PK1
Küffer, S1
Brors, B1
Shahi, P1
Li, L1
Kenzelmann, M1
Gretz, N1
Gröne, HJ1
Noordzij, MA1
van der Kwast, TH1
van Steenbrugge, GJ1
van Weerden, WM1
Oomen, MH1
Berner, A1
Geitvik, G1
Karlsen, F2
Fosså, SD1
Nesland, JM1
Børresen, AL1
Mathai, V1
Seow-Choen, F2
Kalantari, M1
Chitemerere, M1
Johansson, B1
Hagmar, B1
Boon, ME1
van der Poel, HG1
Tan, CJ1
Kok, LP1
Goh, HS1
Eu, KW1
Ho, YH1
Tay, SK1
Stattin, P1
Damber, JE1
Karlberg, L1
Bergh, A1
Googe, PB1
McGinley, KM1
Fitzgibbon, JF1
Chiusa, L1
Galliano, D1
Formiconi, A1
Di Primio, O1
Pich, A1
Vince, DG1
Tbakhi, A1
Gaddipati, A1
Cothren, RM1
Cornhill, JF1
Tubbs, RR1
Tolbert, PE1
Botticelli, AR1
Casali, AM1
Botticelli, L1
Zaffe, D1
Dent, OF1
Galt, E1
Chapuis, PH1
Yuile, P1
Sinclair, G1
Bokey, EL1
Sramkoski, RM1
Wormsley, SW1
Bolton, WE1
Crumpler, DC1
Jacobberger, JW1
Varma, M1
Linden, MD1
Amin, MB1
Spanel, P1
Smith, D1
Holland, TA1
Al Singary, W1
Elder, JB1
Pikarsky, AJ1
Belin, B1
Efron, J1
Weiss, EG1
Nogueras, JJ1
Wexner, SD1
Gown, AM1
Yaziji, H1
Battifora, H1
Cohen, RJ1
Beales, MP1
McNeal, JE1
Jöbsis, AC1
De Vries, GP1
Anholt, RR1
Sanders, GT1
Helms, SR1
Brattain, MG1
Pretlow, TG1
Kreisberg, JI1
Stonington, OG1
Szwec, N1
Webber, M1
Abel, PD1
Keane, P1
Leathem, A1
Tebbutt, S1
Williams, G1
Nakamura, K1
Simon, AL1
Kasabian, NG1
Addonizio, JC1
Choudhury, M1
Nagamatsu, GR1
Rossi, JA1
Chiao, JW1
Blair, A1
Stewart, P1
O'Berg, M1
Gaffey, W1
Walrath, J1
Ward, J1
Bales, R1
Kaplan, S1
Cubit, D1
Ochiai, K1
Takeuchi, H1
Roy, AV1
Brower, ME1
Hayden, JE1
Kreutzmann, H1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Controlled Trial to Investigate the Infectious Outcomes of Intrarectal Povidone-iodine Cleansing Plus Formalin Disinfection of Needle Tip During Transrectal Ultrasound Guided Prostate Biopsy[NCT03879486]1,257 participants (Actual)Interventional2017-05-31Completed
Phase II Trial of Pemetrexed and Bevacizumab for Recurrent Ovarian and Primary Peritoneal Carcinoma[NCT00868192]Phase 238 participants (Actual)Interventional2008-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Overall Response Rate

"Overall response rate = complete response + partial response~Complete response = disappearance of all target and non-target lesions and no evidence of new lesions documented by two disease assessments at least 4 weeks apart.~Partial response = at least a 30% decrease in the sum of the longest dimensions (LD) of all target measurable lesions taking as reference the baseline sum of LD. There can be non unequivocal progression of non-target lesions and no new lesions." (NCT00868192)
Timeframe: 6 months

Interventionpercentage of participants (Number)
Pemetrexed and Bevacizumab41

Overall Survival (OS)

OS = observed length of time from entry into the study to death or date of last contact (NCT00868192)
Timeframe: 12 months

Interventionpercentage of participants (Number)
Pemetrexed and Bevacizumab79

Overall Survival (OS)

OS = observed length of time from entry into the study to death or date of last contact (NCT00868192)
Timeframe: Median follow-up was 25.7 months (range 3.0-47.2 months)

Interventionmonths (Median)
Pemetrexed and Bevacizumab25.7

Progression-free Survival (PFS)

PFS = Period from study entry until disease progression, death, or date of last contact (NCT00868192)
Timeframe: 6 months

Interventionpercentage of participants (Number)
Pemetrexed and Bevacizumab56

Progression-free Survival (PFS)

PFS = Period from study entry until disease progression, death, or date of last contact (NCT00868192)
Timeframe: Median follow-up was 25.7 months (range 3.0-47.2 months)

Interventionmonths (Median)
Pemetrexed and Bevacizumab7.9

CA-125 Response

A CA-125 response was defined as at least a 50% reduction in CA-125 levels from a pretreatment sample following guidelines described by the Gynecological Cancer Intergroup. (NCT00868192)
Timeframe: 6 months

Interventionparticipants (Number)
50% CA-125 response75% CA-125 responseNo CA-125 response
Pemetrexed and Bevacizumab1782

Distribution of Overall Survival (OS)

OS = observed length of time from entry into the study to death or date of last contact (NCT00868192)
Timeframe: Median follow-up was 25.7 months (range 3.0-47.2 months)

Interventionmonths (Median)
Platinum-free interval of <6 monthsPlatinum-free interval of 6-12 monthsPlatinum-free interval of >12 months
Pemetrexed and Bevacizumab16.724.928.0

Distribution of Progression-free Survival (PFS)

PFS = Period from study entry until disease progression, death, or date of last contact (NCT00868192)
Timeframe: Median follow-up was 25.7 months (range 3.0-47.2 months)

Interventionmonths (Median)
Platinum-free interval of <6 monthsPlatinum-free interval of 6-12 monthsPlatinum-free interval of >12 months
Pemetrexed and Bevacizumab6.74.716.8

Frequency of Clinical Response

As measured by RECIST criteria (NCT00868192)
Timeframe: 6 months

Interventionparticipants (Number)
Complete responsePartial responseStable diseaseProgressive disease
Pemetrexed and Bevacizumab014182

Toxicity Associated With Bevacizumab and Pemetrexed

Detailed serious adverse events and other adverse events are shown in the adverse event module of the results. (NCT00868192)
Timeframe: 6 months

Interventionpercentage of participants (Number)
Grade 3/4 hematologic toxicityMost common non-hematologic toxicity - fatigueGrade 3 renal toxicityGastrointestinal toxicitySubsequently developed hematologic malignancies
Pemetrexed and Bevacizumab53946916

Reviews

4 reviews available for formaldehyde and Cancer of Prostate

ArticleYear
Molecular profiling of indolent human prostate cancer: tackling technical challenges to achieve high-fidelity genome-wide data.
    Asian journal of andrology, 2012, Volume: 14, Issue:3

    Topics: Biomarkers, Tumor; Disease Progression; DNA, Neoplasm; Epigenesis, Genetic; Formaldehyde; Gene Expre

2012
Handling of clinical tissue specimens for molecular profiling studies.
    Current issues in molecular biology, 2003, Volume: 5, Issue:2

    Topics: Cryopreservation; DNA, Complementary; Formaldehyde; Gene Expression Profiling; Humans; Internet; Mal

2003
Oils and cancer.
    Cancer causes & control : CCC, 1997, Volume: 8, Issue:3

    Topics: 2-Naphthylamine; Benzo(a)pyrene; Carcinogens; Chlorine Compounds; Esophageal Neoplasms; Ethanolamine

1997
[Acid phosphatase--how to read its figures].
    Nihon rinsho. Japanese journal of clinical medicine, 1971, Volume: 29

    Topics: Acid Phosphatase; Clinical Enzyme Tests; Ethanol; Formaldehyde; Glycerophosphates; Hot Temperature;

1971

Trials

2 trials available for formaldehyde and Cancer of Prostate

ArticleYear
Argon plasma coagulation therapy versus topical formalin for intractable rectal bleeding and anorectal dysfunction after radiation therapy for prostate carcinoma.
    International journal of radiation oncology, biology, physics, 2013, Dec-01, Volume: 87, Issue:5

    Topics: Administration, Topical; Aged; Aged, 80 and over; Anal Canal; Argon Plasma Coagulation; Coagulants;

2013
Exome enrichment and SOLiD sequencing of formalin fixed paraffin embedded (FFPE) prostate cancer tissue.
    International journal of molecular sciences, 2012, Volume: 13, Issue:7

    Topics: Cryopreservation; Exome; Formaldehyde; High-Throughput Nucleotide Sequencing; Humans; Male; Paraffin

2012

Other Studies

104 other studies available for formaldehyde and Cancer of Prostate

ArticleYear
A prostate cancer tissue specific spectral library for targeted proteomic analysis.
    Proteomics, 2022, Volume: 22, Issue:7

    Topics: Formaldehyde; Humans; Male; Mass Spectrometry; Paraffin Embedding; Prostatic Neoplasms; Proteins; Pr

2022
Automated quantitative high-throughput multiplex immunofluorescence pipeline to evaluate OXPHOS defects in formalin-fixed human prostate tissue.
    Scientific reports, 2022, 04-22, Volume: 12, Issue:1

    Topics: Electron Transport Complex IV; Fluorescent Antibody Technique; Formaldehyde; Humans; Male; Oxidative

2022
Distinct expression signatures of miR-130a, miR-301a, miR-454 in formalin fixed paraffin embedded tissue samples of prostate cancer patients.
    Pathology, research and practice, 2022, Volume: 234

    Topics: Biomarkers, Tumor; Formaldehyde; Humans; Male; MicroRNAs; Paraffin Embedding; Prostatic Neoplasms

2022
Proteomics Analysis of Formalin Fixed Paraffin Embedded Tissues in the Investigation of Prostate Cancer.
    Journal of proteome research, 2020, 07-02, Volume: 19, Issue:7

    Topics: Animals; Chromatography, Liquid; Formaldehyde; Humans; Male; Mice; Paraffin Embedding; Prostatic Neo

2020
Evaluation and Management of Chronic Radiation Proctitis.
    Diseases of the colon and rectum, 2020, Volume: 63, Issue:3

    Topics: Administration, Rectal; Aged; Chronic Disease; Formaldehyde; Humans; Male; Proctitis; Prostatic Neop

2020
Comparative analysis of somatic variant calling on matched FF and FFPE WGS samples.
    BMC medical genomics, 2020, 07-06, Volume: 13, Issue:1

    Topics: Biomarkers, Tumor; DNA, Neoplasm; Feasibility Studies; Formaldehyde; Gene Expression Profiling; Gene

2020
Design and Development of a Fully Synthetic Multiplex Ligation-Dependent Probe Amplification-Based Probe Mix for Detection of Copy Number Alterations in Prostate Cancer Formalin-Fixed, Paraffin-Embedded Tissue Samples.
    The Journal of molecular diagnostics : JMD, 2020, Volume: 22, Issue:10

    Topics: Cell Line, Tumor; DNA Copy Number Variations; DNA Probes; DNA, Neoplasm; Formaldehyde; Genome, Human

2020
The potential role of fatty acids in prostate cancer determined by GC-MS analysis of formalin-fixed paraffin-embedded tissue samples.
    Journal of pharmaceutical and biomedical analysis, 2021, Mar-20, Volume: 196

    Topics: Fatty Acids; Formaldehyde; Gas Chromatography-Mass Spectrometry; Humans; Male; Metabolomics; Paraffi

2021
Novel RNA biomarkers of prostate cancer revealed by RNA-seq analysis of formalin-fixed samples obtained from Russian patients.
    Oncotarget, 2017, May-16, Volume: 8, Issue:20

    Topics: Aged; Formaldehyde; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulato

2017
Impact of the G84E variant on HOXB13 gene and protein expression in formalin-fixed, paraffin-embedded prostate tumours.
    Scientific reports, 2017, 12-19, Volume: 7, Issue:1

    Topics: Alleles; Case-Control Studies; Cohort Studies; DNA Methylation; Formaldehyde; Gene Expression; Genet

2017
RNA-based markers in biopsy cores with atypical small acinar proliferation: Predictive effect of T2E fusion positivity and MMP-2 upregulation for a subsequent prostate cancer diagnosis.
    The Prostate, 2019, Volume: 79, Issue:2

    Topics: Aged; Biomarkers, Tumor; Biopsy, Large-Core Needle; Disease-Free Survival; Formaldehyde; Humans; Mal

2019
Quantity and quality of nucleic acids extracted from archival formalin fixed paraffin embedded prostate biopsies.
    BMC medical research methodology, 2018, 12-05, Volume: 18, Issue:1

    Topics: Biopsy; Female; Fixatives; Formaldehyde; Humans; Male; Nucleic Acids; Paraffin Embedding; Prostate;

2018
A M-MLV reverse transcriptase with reduced RNaseH activity allows greater sensitivity of gene expression detection in formalin fixed and paraffin embedded prostate cancer samples.
    Experimental and molecular pathology, 2013, Volume: 95, Issue:1

    Topics: Formaldehyde; Gene Expression Profiling; Humans; Limit of Detection; Male; Moloney murine leukemia v

2013
Treatment of hemorrhagic radiation-induced proctopathy with a 4% formalin application under perianal anesthetic infiltration.
    World journal of gastroenterology, 2013, Aug-14, Volume: 19, Issue:30

    Topics: Administration, Rectal; Aged; Anesthesia, Local; Drug Administration Schedule; Formaldehyde; Gastroi

2013
Assessment of the 2-d gel-based proteomics application of clinically archived formalin-fixed paraffin embedded tissues.
    The protein journal, 2014, Volume: 33, Issue:2

    Topics: Biomarkers, Tumor; Breast; Breast Neoplasms; Cryopreservation; Electrophoresis, Gel, Two-Dimensional

2014
Use of Sequenom sample ID Plus® SNP genotyping in identification of FFPE tumor samples.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: DNA, Neoplasm; Fixatives; Formaldehyde; Genetic Markers; Genotyping Techniques; Humans; Male; Micros

2014
Global transcriptome analysis of formalin-fixed prostate cancer specimens identifies biomarkers of disease recurrence.
    Cancer research, 2014, Jun-15, Volume: 74, Issue:12

    Topics: Adult; Biomarkers, Tumor; Fixatives; Formaldehyde; Gene Expression Profiling; Humans; Kaplan-Meier E

2014
MALDI imaging mass spectrometry profiling of N-glycans in formalin-fixed paraffin embedded clinical tissue blocks and tissue microarrays.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Adult; Animals; Carbohydrate Sequence; Carcinoma, Hepatocellular; Female; Formaldehyde; Humans; Hydr

2014
Quantitative analysis of ERG expression and its splice isoforms in formalin-fixed, paraffin-embedded prostate cancer samples: association with seminal vesicle invasion and biochemical recurrence.
    American journal of clinical pathology, 2014, Volume: 142, Issue:4

    Topics: Alternative Splicing; Exons; Formaldehyde; Gene Expression Regulation, Neoplastic; Humans; Immunohis

2014
Mutation detection in formalin-fixed prostate cancer biopsies taken at the time of diagnosis using next-generation DNA sequencing.
    Journal of clinical pathology, 2015, Volume: 68, Issue:3

    Topics: Aged; Biomarkers, Tumor; Biopsy, Fine-Needle; DNA Mutational Analysis; Fixatives; Formaldehyde; Gene

2015
Genetically engineered mouse models to study prostate cancer.
    Methods in molecular biology (Clifton, N.J.), 2015, Volume: 1267

    Topics: Animals; Disease Models, Animal; Dissection; Eosine Yellowish-(YS); Formaldehyde; Genetic Engineerin

2015
Integrative molecular profiling of routine clinical prostate cancer specimens.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:6

    Topics: Biomarkers, Tumor; Biopsy; DNA Copy Number Variations; DNA Mutational Analysis; Feasibility Studies;

2015
Prostate Biopsy Core Handling: Comparison of Contemporary Preembedding Methods.
    Urologia internationalis, 2015, Volume: 95, Issue:2

    Topics: Biopsy, Large-Core Needle; Formaldehyde; Glass; Humans; Male; Materials Testing; Paper; Prostate; Pr

2015
Overexpression of the novel senescence marker β-galactosidase (GLB1) in prostate cancer predicts reduced PSA recurrence.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Aged; Antineoplastic Agents; Aziridines; Benzoquinones; beta-Galactosidase; Biomarkers; Cellular Sen

2015
Comparing Platforms for Messenger RNA Expression Profiling of Archival Formalin-Fixed, Paraffin-Embedded Tissues.
    The Journal of molecular diagnostics : JMD, 2015, Volume: 17, Issue:4

    Topics: Clinical Trials, Phase III as Topic; Female; Formaldehyde; Gene Expression Profiling; Humans; Male;

2015
Targeting cells of the myeloid lineage attenuates pain and disease progression in a prostate model of bone cancer.
    Pain, 2015, Volume: 156, Issue:9

    Topics: Aminopyridines; Analgesics; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Bone a

2015
Formalin therapy for hemorrhagic radiation proctitis.
    Pharmacological reports : PR, 2015, Volume: 67, Issue:5

    Topics: Administration, Rectal; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Argon; Asp

2015
Development of a registration framework to validate MRI with histology for prostate focal therapy.
    Medical physics, 2015, Volume: 42, Issue:12

    Topics: Aged; Atlases as Topic; Cell Count; Fixatives; Formaldehyde; Gels; Histological Techniques; Humans;

2015
A pilot study on the expression of microRNAs resident on chromosome 21 in laser microdissected FFPE prostate adenocarcinoma samples.
    Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie, 2015, Volume: 56, Issue:3

    Topics: Adenocarcinoma; Chromosomes, Human, Pair 21; Formaldehyde; Gene Expression Regulation, Neoplastic; H

2015
Improving the Prediction of Prostate Cancer Overall Survival by Supplementing Readily Available Clinical Data with Gene Expression Levels of IGFBP3 and F3 in Formalin-Fixed Paraffin Embedded Core Needle Biopsy Material.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Aged; Aged, 80 and over; Biopsy, Large-Core Needle; Cohort Studies; Formaldehyde; Gene Expression Re

2016
Differentiating tumor heterogeneity in formalin-fixed paraffin-embedded (FFPE) prostate adenocarcinoma tissues using principal component analysis of matrix-assisted laser desorption/ionization imaging mass spectral data.
    Rapid communications in mass spectrometry : RCM, 2017, Jan-30, Volume: 31, Issue:2

    Topics: Adenocarcinoma; Biomarkers, Tumor; Formaldehyde; Humans; Male; Paraffin Embedding; Principal Compone

2017
Differential long-term stability of microRNAs and RNU6B snRNA in 12-20 year old archived formalin-fixed paraffin-embedded specimens.
    BMC cancer, 2017, 01-06, Volume: 17, Issue:1

    Topics: Formaldehyde; Gene Expression Regulation, Neoplastic; Humans; Male; MicroRNAs; Paraffin Embedding; P

2017
Formalin disinfection of prostate biopsy needles may reduce post-biopsy infectious complications.
    Prostate cancer and prostatic diseases, 2017, Volume: 20, Issue:2

    Topics: Aged; Anti-Bacterial Agents; Biopsy, Needle; Disinfection; Formaldehyde; Humans; Male; Middle Aged;

2017
High-resolution imaging using a novel atomic force microscope and confocal laser scanning microscope hybrid instrument: essential sample preparation aspects.
    Histochemistry and cell biology, 2008, Volume: 130, Issue:5

    Topics: Cell Line, Tumor; Fixatives; Formaldehyde; Humans; Image Processing, Computer-Assisted; Intercellula

2008
KLF6 and TP53 mutations are a rare event in prostate cancer: distinguishing between Taq polymerase artifacts and true mutations.
    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 2008, Volume: 21, Issue:12

    Topics: Artifacts; Base Sequence; DNA Mutational Analysis; Formaldehyde; Humans; Kruppel-Like Factor 6; Krup

2008
Spectral analysis of multiplex Raman probe signatures.
    ACS nano, 2008, Nov-25, Volume: 2, Issue:11

    Topics: Automation; Biological Assay; Fluorescent Dyes; Formaldehyde; Humans; Keratin-18; Male; Nanoparticle

2008
Formamide as a denaturant for bisulfite conversion of genomic DNA: Bisulfite sequencing of the GSTPi and RARbeta2 genes of 43 formalin-fixed paraffin-embedded prostate cancer specimens.
    Analytical biochemistry, 2009, Sep-15, Volume: 392, Issue:2

    Topics: Base Sequence; Biomarkers, Tumor; Biopsy; DNA Methylation; DNA, Neoplasm; Formaldehyde; Formamides;

2009
An improved method for constructing tissue microarrays from prostate needle biopsy specimens.
    Journal of clinical pathology, 2009, Volume: 62, Issue:8

    Topics: Biomarkers, Tumor; Biopsy, Needle; Fixatives; Formaldehyde; Humans; In Situ Hybridization, Fluoresce

2009
Oral vitamin A enhances the effectiveness of formalin 8% in treating chronic hemorrhagic radiation proctopathy.
    Diseases of the colon and rectum, 2009, Volume: 52, Issue:9

    Topics: Administration, Oral; Aged; Aged, 80 and over; Carcinoma; Cohort Studies; Dietary Supplements; Forma

2009
mRNA and micro-RNA expression analysis in laser-capture microdissected prostate biopsies: valuable tool for risk assessment and prevention trials.
    Experimental and molecular pathology, 2010, Volume: 88, Issue:1

    Topics: Biomarkers, Tumor; Biopsy, Needle; Feasibility Studies; Formaldehyde; Frozen Sections; Gene Expressi

2010
Combined effects of formalin fixation and tissue processing on immunorecognition.
    Biotechnic & histochemistry : official publication of the Biological Stain Commission, 2009, Volume: 84, Issue:5

    Topics: Antigens; Cell Line, Tumor; Ethanol; Female; Fixatives; Formaldehyde; Humans; Immunohistochemistry;

2009
Tumor tissue-derived formaldehyde and acidic microenvironment synergistically induce bone cancer pain.
    PloS one, 2010, Apr-21, Volume: 5, Issue:4

    Topics: Acids; Animals; Bone Neoplasms; Breast Neoplasms; CHO Cells; Cricetinae; Cricetulus; Female; Formald

2010
Formalin fixation and immunoreactivity in prostate cancer and benign prostatic tissues.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2010, Volume: 118, Issue:5

    Topics: Adenocarcinoma; Biomarkers, Tumor; Formaldehyde; Humans; Immunohistochemistry; Injections, Intralesi

2010
High-density tissue microarrays from prostate needle biopsies.
    Journal of clinical pathology, 2011, Volume: 64, Issue:1

    Topics: Biomarkers, Tumor; Biopsy, Needle; Formaldehyde; Humans; Male; Prospective Studies; Prostatic Neopla

2011
Multivariate analyses for biomarkers hunting and validation through on-tissue bottom-up or in-source decay in MALDI-MSI: application to prostate cancer.
    Analytical and bioanalytical chemistry, 2011, Volume: 401, Issue:1

    Topics: Amino Acid Sequence; Animals; Biomarkers, Tumor; Formaldehyde; Humans; Male; Molecular Sequence Data

2011
Laser-capture microdissection and transcriptional profiling in archival FFPE tissue in prostate cancer.
    Methods in molecular biology (Clifton, N.J.), 2011, Volume: 755

    Topics: Fixatives; Formaldehyde; Gene Expression Profiling; Humans; Lasers; Male; Microdissection; Paraffin

2011
DNA extraction columns contaminated with murine sequences.
    PloS one, 2011, Volume: 6, Issue:8

    Topics: Animals; Base Sequence; Biochemistry; DNA Contamination; DNA, Neoplasm; Formaldehyde; Humans; Leukem

2011
PTEN protein loss by immunostaining: analytic validation and prognostic indicator for a high risk surgical cohort of prostate cancer patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Oct-15, Volume: 17, Issue:20

    Topics: Cell Line, Tumor; Cohort Studies; Formaldehyde; Gene Deletion; Humans; Immunohistochemistry; Male; P

2011
Targeted high throughput sequencing in clinical cancer settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity.
    BMC medical genomics, 2011, Sep-29, Volume: 4

    Topics: DNA Copy Number Variations; DNA, Neoplasm; Formaldehyde; Genetic Heterogeneity; Humans; Male; Paraff

2011
Biexponential diffusion decay in formalin-fixed prostate tissue: preliminary findings.
    Magnetic resonance in medicine, 2012, Volume: 68, Issue:3

    Topics: Algorithms; Computer Simulation; Diffusion; Fixatives; Formaldehyde; Humans; Image Enhancement; Imag

2012
Formalin dab for treatment of haemorrhagic radiation proctitis.
    BMJ case reports, 2011, Jul-20, Volume: 2011

    Topics: Administration, Topical; Aged; Formaldehyde; Gastrointestinal Hemorrhage; Humans; Male; Proctitis; P

2011
Application of pyrosequencing technique for improved detection of K-Ras mutation in formalin-fixed and paraffin-embedded prostate carcinoma tissues in Chinese patients.
    Clinica chimica acta; international journal of clinical chemistry, 2012, Oct-09, Volume: 413, Issue:19-20

    Topics: Aged; Asian People; Carcinoma; Case-Control Studies; Cell Line, Tumor; Codon; Fixatives; Formaldehyd

2012
Microscopic diffusivity compartmentation in formalin-fixed prostate tissue.
    Magnetic resonance in medicine, 2012, Volume: 68, Issue:2

    Topics: Fixatives; Formaldehyde; Humans; Image Enhancement; Image Interpretation, Computer-Assisted; Male; P

2012
A simple way to improve immunoreactivity of prostate needle biopsies fixed in Bouin's solution to AMACR.
    Applied immunohistochemistry & molecular morphology : AIMM, 2013, Volume: 21, Issue:3

    Topics: Acetic Acid; Adenocarcinoma; Biopsy, Needle; Ethanol; Fixatives; Formaldehyde; Humans; Immunohistoch

2013
Targeted next-generation sequencing of advanced prostate cancer identifies potential therapeutic targets and disease heterogeneity.
    European urology, 2013, Volume: 63, Issue:5

    Topics: Androgen Antagonists; Antineoplastic Agents, Hormonal; Biopsy, Needle; Drug Resistance, Neoplasm; Ex

2013
Preservation of immunorecognition by transferring cells from 10% neutral buffered formalin to 70% ethanol.
    Biotechnic & histochemistry : official publication of the Biological Stain Commission, 2013, Volume: 88, Issue:3-4

    Topics: Cell Line, Tumor; ErbB Receptors; Ethanol; Female; Fixatives; Formaldehyde; Humans; Immunohistochemi

2013
Chemiluminescent measurement of telomere DNA content in biopsies.
    BioTechniques, 2002, Volume: 33, Issue:1

    Topics: Biopsy; Blotting, Southern; DNA; Female; Formaldehyde; HeLa Cells; Humans; Luminescent Measurements;

2002
Inadequate formalin fixation decreases reliability of p27 immunohistochemical staining: probing optimal fixation time using high-density tissue microarrays.
    Human pathology, 2002, Volume: 33, Issue:7

    Topics: Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p27; Down-Regulation; Fixatives; Formaldehyde

2002
High-resolution analysis of paraffin-embedded and formalin-fixed prostate tumors using comparative genomic hybridization to genomic microarrays.
    The American journal of pathology, 2003, Volume: 162, Issue:3

    Topics: Chromosome Aberrations; Chromosome Mapping; Formaldehyde; Histological Techniques; Humans; Male; Neo

2003
A modified reduced-temperature antigen retrieval protocol effective for use with a polyclonal antibody to cyclooxygenase-2 (PG 27).
    Applied immunohistochemistry & molecular morphology : AIMM, 2002, Volume: 10, Issue:4

    Topics: Antibodies; Antigens; Breast Neoplasms; Cyclooxygenase 2; Female; Formaldehyde; Hot Temperature; Hum

2002
The use of formalin and alcohol in the estimation of prostatic phosphatase.
    The Journal of urology, 1951, Volume: 66, Issue:5

    Topics: Ethanol; Formaldehyde; Humans; Male; Phosphoric Monoester Hydrolases; Prostatic Neoplasms

1951
Studies of targeting and intracellular trafficking of an anti-androgen doxorubicin-formaldehyde conjugate in PC-3 prostate cancer cells bearing androgen receptor-GFP chimera.
    Journal of medicinal chemistry, 2004, Nov-04, Volume: 47, Issue:23

    Topics: Androgen Antagonists; Doxorubicin; Formaldehyde; Green Fluorescent Proteins; Humans; Imidazoles; Lig

2004
Gene expression profiles in formalin-fixed, paraffin-embedded tissues obtained with a novel assay for microarray analysis.
    Clinical chemistry, 2004, Volume: 50, Issue:12

    Topics: Adenocarcinoma; Breast Neoplasms; Colonic Neoplasms; Female; Fixatives; Formaldehyde; Gene Expressio

2004
Construction and application of a full-coverage, high-resolution, human chromosome 8q genomic microarray for comparative genomic hybridization.
    Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2005, Volume: 63, Issue:1

    Topics: Adenocarcinoma; Cardia; Chromosome Aberrations; Chromosomes, Human, Pair 8; Fixatives; Formaldehyde;

2005
Endoscopic and histopathologic findings after formalin application for hemorrhage caused by chronic radiation-induced proctitis.
    Gastrointestinal endoscopy, 2005, Volume: 61, Issue:1

    Topics: Aged; Fixatives; Formaldehyde; Gastrointestinal Hemorrhage; Humans; Male; Proctitis; Prostatic Neopl

2005
Immunohistochemical assays in prostatic biopsies processed in Bouin's fixative.
    Journal of clinical pathology, 2005, Volume: 58, Issue:3

    Topics: Acetic Acid; Biomarkers, Tumor; Biopsy; Cell Cycle Proteins; Cell Nucleus; Cyclin-Dependent Kinase I

2005
Inhibitory effects of a selective endothelin-A receptor antagonist YM598 on endothelin-1-induced potentiation of nociception in formalin-induced and prostate cancer-induced pain models in mice.
    Journal of cardiovascular pharmacology, 2004, Volume: 44 Suppl 1

    Topics: Administration, Oral; Analgesics, Non-Narcotic; Animals; Behavior, Animal; Cell Line, Tumor; Disease

2004
Expression of thymidylate synthase, dihydropyrimidine dehydrogenase, thymidine phosphorylase, and orotate phosphoribosyl transferase in prostate cancer.
    Prostate cancer and prostatic diseases, 2005, Volume: 8, Issue:3

    Topics: Cell Differentiation; Dihydrouracil Dehydrogenase (NADP); DNA Primers; Formaldehyde; Gene Expression

2005
Proteomic analysis of formalin-fixed prostate cancer tissue.
    Molecular & cellular proteomics : MCP, 2005, Volume: 4, Issue:11

    Topics: Amino Acid Sequence; Cytokines; Formaldehyde; Gene Expression Profiling; Gene Expression Regulation,

2005
Unravelling the proteome of formalin-fixed paraffin-embedded tissue.
    Briefings in functional genomics & proteomics, 2006, Volume: 5, Issue:2

    Topics: Animals; Biomarkers; Fixatives; Formaldehyde; Lasers; Male; Mass Spectrometry; Microdissection; Neop

2006
Direct cancer tissue proteomics: a method to identify candidate cancer biomarkers from formalin-fixed paraffin-embedded archival tissues.
    Oncogene, 2007, Jan-04, Volume: 26, Issue:1

    Topics: Amino Acid Sequence; Biomarkers, Tumor; Computational Biology; Formaldehyde; Humans; Immunohistochem

2007
Tissue shrinkage after fixation with formalin injection of prostatectomy specimens.
    Virchows Archiv : an international journal of pathology, 2006, Volume: 449, Issue:3

    Topics: Artifacts; Fixatives; Formaldehyde; Humans; Male; Organ Size; Prostatectomy; Prostatic Neoplasms; Ti

2006
Expression signatures that correlated with Gleason score and relapse in prostate cancer.
    Genomics, 2007, Volume: 89, Issue:6

    Topics: Aged; Aged, 80 and over; Formaldehyde; Gene Expression Profiling; Humans; Male; Middle Aged; Oligonu

2007
Transcriptome analyses of benign and malignant prostate epithelial cells in formalin-fixed paraffin-embedded whole-mounted radical prostatectomy specimens.
    Prostate cancer and prostatic diseases, 2008, Volume: 11, Issue:2

    Topics: Adenocarcinoma; Dissection; Epithelial Cells; Formaldehyde; Gene Expression Profiling; Humans; Image

2008
Evaluation of the branched-chain DNA assay for measurement of RNA in formalin-fixed tissues.
    The Journal of molecular diagnostics : JMD, 2008, Volume: 10, Issue:2

    Topics: Animals; Biological Specimen Banks; Branched DNA Signal Amplification Assay; Formaldehyde; Gene Expr

2008
Application of transcript profiling in formalin-fixed paraffin-embedded diagnostic prostate cancer needle biopsies.
    BJU international, 2008, Volume: 102, Issue:3

    Topics: Biopsy, Needle; Cell Line, Tumor; Cohort Studies; Feasibility Studies; Formaldehyde; Gene Expression

2008
Detection of the TMPRSS2-ETS fusion gene in prostate carcinomas: retrospective analysis of 55 formalin-fixed and paraffin-embedded samples with clinical data.
    Cancer genetics and cytogenetics, 2008, Volume: 183, Issue:1

    Topics: Adenocarcinoma; Adenovirus E1A Proteins; Aged; Aged, 80 and over; DNA-Binding Proteins; Feasibility

2008
A cut-off based approach for gene expression analysis of formalin-fixed and paraffin-embedded tissue samples.
    Genomics, 2008, Volume: 91, Issue:6

    Topics: Analysis of Variance; Fixatives; Formaldehyde; Gene Expression Profiling; Gene Expression Regulation

2008
Determination of Ki-67 defined growth fraction by monoclonal antibody MIB-1 in formalin-fixed, paraffin-embedded prostatic cancer tissues.
    The Prostate, 1995, Volume: 27, Issue:3

    Topics: Adenocarcinoma; Animals; Antibodies, Monoclonal; Bromodeoxyuridine; Cell Division; Formaldehyde; Fro

1995
TP53 mutations in prostatic cancer. Analysis of pre- and post-treatment archival formalin-fixed tumour tissue.
    The Journal of pathology, 1995, Volume: 176, Issue:3

    Topics: Aged; Aged, 80 and over; Electrophoresis; Formaldehyde; Genes, p53; Humans; Male; Middle Aged; Mutat

1995
Endoluminal formalin therapy for haemorrhagic radiation proctitis.
    The British journal of surgery, 1995, Volume: 82, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Brachytherapy; Female; Formaldehyde; Gastrointestinal Hemorrhage; Hu

1995
Modifications of human and viral deoxyribonucleic acid by formaldehyde fixation.
    Laboratory investigation; a journal of technical methods and pathology, 1994, Volume: 71, Issue:4

    Topics: Base Sequence; DNA; DNA Damage; DNA, Neoplasm; DNA, Viral; Formaldehyde; Humans; Kidney; Male; Molec

1994
Effect of embedding methods versus fixative type on karyometric measures.
    Analytical and quantitative cytology and histology, 1994, Volume: 16, Issue:2

    Topics: Cell Nucleus; Ethanol; Fixatives; Formaldehyde; Humans; Image Processing, Computer-Assisted; Karyome

1994
A simple and effective treatment for hemorrhagic radiation proctitis using formalin.
    Diseases of the colon and rectum, 1993, Volume: 36, Issue:2

    Topics: Adult; Aged; Female; Follow-Up Studies; Formaldehyde; Gastrointestinal Hemorrhage; Humans; Male; Mid

1993
Cell proliferation assessed by Ki-67 immunoreactivity on formalin fixed tissues is a predictive factor for survival in prostate cancer.
    The Journal of urology, 1997, Volume: 157, Issue:1

    Topics: Aged; Aged, 80 and over; Cell Division; Formaldehyde; Humans; Immunohistochemistry; Ki-67 Antigen; M

1997
Anticytokeratin antibody 34 beta E12 staining in prostate carcinoma.
    American journal of clinical pathology, 1997, Volume: 107, Issue:2

    Topics: Adenocarcinoma; Biomarkers, Tumor; Formaldehyde; Humans; Keratins; Lymphatic Metastasis; Male; Prost

1997
High and low risk prostate carcinoma determined by histologic grade and proliferative activity.
    Cancer, 1997, May-15, Volume: 79, Issue:10

    Topics: Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Agents, Hormonal; Biopsy, Needle; Carc

1997
Quantitative comparison of immunohistochemical staining intensity in tissues fixed in formalin and Histochoice.
    Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology, 1997, Volume: 15, Issue:2

    Topics: Analysis of Variance; Antigens, CD20; Carcinoma; Chromogranins; Colonic Neoplasms; Factor VIII; Fixa

1997
Immunohistochemical detection of cell-cycle associated markers on paraffin embedded and formalin fixed needle biopsies of prostate cancer: correlation of p120 protein expression with AgNOR, PCNA/cyclin, Ki-67/MIB1 proliferation-scores and Gleason gradings
    European journal of histochemistry : EJH, 1998, Volume: 42, Issue:1

    Topics: Aged; Biopsy, Needle; Cell Cycle; Cyclins; Evaluation Studies as Topic; Fixatives; Formaldehyde; Hum

1998
Quality of life in patients undergoing treatment for chronic radiation-induced rectal bleeding.
    The British journal of surgery, 1998, Volume: 85, Issue:9

    Topics: Aged; Aged, 80 and over; Chronic Disease; Depression; Female; Formaldehyde; Gastrointestinal Hemorrh

1998
Simultaneous detection of cyclin B1, p105, and DNA content provides complete cell cycle phase fraction analysis of cells that endoreduplicate.
    Cytometry, 1999, Mar-01, Volume: 35, Issue:3

    Topics: Benzimidazoles; Cell Cycle; Cell Line; Cell Separation; Cells, Immobilized; Cyclin B; Cyclin B1; DNA

1999
Effect of formalin fixation and epitope retrieval techniques on antibody 34betaE12 immunostaining of prostatic tissues.
    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 1999, Volume: 12, Issue:5

    Topics: Antibodies, Monoclonal; Epitopes; Formaldehyde; Histocytological Preparation Techniques; Hot Tempera

1999
Analysis of formaldehyde in the headspace of urine from bladder and prostate cancer patients using selected ion flow tube mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 1999, Volume: 13, Issue:14

    Topics: Formaldehyde; Humans; Male; Mass Spectrometry; Prostatic Neoplasms; Urinary Bladder Neoplasms; Urine

1999
Complications following formalin installation in the treatment of radiation induced proctitis.
    International journal of colorectal disease, 2000, Volume: 15, Issue:2

    Topics: Aged; Aged, 80 and over; Fecal Incontinence; Female; Formaldehyde; Gastrointestinal Hemorrhage; Huma

2000
Correspondence re: Varma M, Linden MD, Amin MB. Effect of formalin fixation and epitope retrieval techniques on antibody 34betaE12 immunostaining of prostatic tissues. Mod Pathol 1999;12:472-8.
    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 2000, Volume: 13, Issue:7

    Topics: Antibodies, Monoclonal; Biomarkers, Tumor; Epitopes; Formaldehyde; Histocytological Preparation Tech

2000
Prostate secretory granules in normal and neoplastic prostate glands: a diagnostic aid to needle biopsy.
    Human pathology, 2000, Volume: 31, Issue:12

    Topics: Adenocarcinoma; Biopsy, Needle; Formaldehyde; Glutaral; Humans; Male; Prostate; Prostatic Intraepith

2000
Demonstration of the prostatic origin of metastases: an immunohistochemical method for formalin-fixed embedded tissue.
    Cancer, 1978, Volume: 41, Issue:5

    Topics: Acid Phosphatase; Formaldehyde; Humans; Immunoenzyme Techniques; Isoenzymes; Male; Neoplasm Metastas

1978
"Prostatic acid phosphatase?" A comparison of acid phosphatase activities in epithelial cells, granulocytes, monocytes, lymphocytes, and platelets purified by velocity sedimentation in isokinetic gradients of Ficoll in tissue culture medium.
    The American journal of pathology, 1977, Volume: 88, Issue:3

    Topics: Acid Phosphatase; Blood Platelets; Copper; Epithelial Cells; Epithelium; Fluorides; Formaldehyde; Gr

1977
Isolation and identification of the human malignant prostatic epithelial cell in pure monolayer culture.
    The Journal of urology, 1975, Volume: 114, Issue:6

    Topics: Acid Phosphatase; Cells, Cultured; Epithelial Cells; Epithelium; Formaldehyde; Humans; Lymphatic Met

1975
Change in glycoconjugate for the binding site of the lectin Ulex europeus 1 following malignant transformation of prostatic epithelium.
    British journal of urology, 1989, Volume: 63, Issue:2

    Topics: Aged; Aged, 80 and over; Binding Sites; Cell Transformation, Neoplastic; Formaldehyde; Frozen Sectio

1989
Flow cytometric analysis of relative mean DNA content of urogenital cancer cells in fresh and paraffin-embedded materials.
    Urology, 1987, Volume: 30, Issue:4

    Topics: DNA, Neoplasm; Fixatives; Flow Cytometry; Formaldehyde; Histological Techniques; Humans; Kidney Neop

1987
Mortality among industrial workers exposed to formaldehyde.
    Journal of the National Cancer Institute, 1986, Volume: 76, Issue:6

    Topics: Adult; Environmental Exposure; Female; Formaldehyde; Hodgkin Disease; Humans; Industry; Leukemia; Lu

1986
Sodium thymolphthalein monophosphate: a new acid phosphatase substrate with greater specificity for the prostatic enzyme in serum.
    Clinical chemistry, 1971, Volume: 17, Issue:11

    Topics: Acid Phosphatase; Biliary Tract Diseases; Blood Platelets; Bone and Bones; Breast Neoplasms; Erythro

1971
[Determination and establishment of normal limits of total and prostatic acid phosphatase activity].
    Zeitschrift fur Urologie und Nephrologie, 1970, Volume: 63, Issue:11

    Topics: Acid Phosphatase; Blood Platelets; Female; Formaldehyde; Germany, East; Humans; Male; Methods; Nitro

1970