formaldehyde has been researched along with Cancer of Nose in 81 studies
paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy
Excerpt | Relevance | Reference |
---|---|---|
"Formaldehyde is a well known nasal carcinogen in rodents, but so far there has been no convincing evidence that workers occupationally exposed to formaldehyde have an increased risk of nasal cancer." | 5.28 | Malignant melanomas of the nasal cavity after occupational exposure to formaldehyde. ( Holmstrom, M; Lund, VJ, 1991) |
" Examples for nasal tumor induction by formaldehyde and for the induction of renal adenocarcinoma by ochratoxin A are shown." | 3.71 | Statistical procedures to test for linearity and estimate threshold doses for tumor induction with nonlinear dose-response relationships in bioassays for carcinogenicity. ( Lutz, RW; Lutz, WK; Stahel, WA, 2002) |
"Thus, prevention of nasal cancer is considered to prevent lymphohematopoietic malignancies." | 2.46 | Cancer effects of formaldehyde: a proposal for an indoor air guideline value. ( Nielsen, GD; Wolkoff, P, 2010) |
"Three types of cancer were assessed: nasopharyngeal cancer, leukemia and sinonasal cancer." | 2.44 | [Assessment of carcinogenicity of formaldehyde based on the newest literature data]. ( Kupczewska-Dobecka, M, 2007) |
"Molecular genetic studies on nasal squamous cell carcinomas (SCC) in rats thus far have indicated the presence of oncogenes unrelated to the ras oncogene family and that p53 mutation occurs at a high frequency among the nasal SCC examined." | 2.40 | Oncogene and tumor suppressor gene alterations in nasal tumors. ( Recio, L, 1997) |
"Sulfuric acid appears to cause laryngeal cancer." | 2.40 | Reactive chemicals and cancer. ( Blair, A; Kazerouni, N, 1997) |
"Formaldehyde is a nasal carcinogen in the rat but the cancer risk this chemical poses for humans remains to be determined." | 2.39 | Cell proliferation and formaldehyde-induced respiratory carcinogenesis. ( Monticello, TM; Morgan, KT, 1994) |
" Dose-response data from human exposure situations would provide the most solid foundation for risk assessment, avoiding problematic extrapolations from the health effects seen in nonhuman species." | 2.38 | Quantitative cancer risk estimation for formaldehyde. ( Starr, TB, 1990) |
"Formaldehyde was recently shown to be carcinogenic in the nasal cavities of rats and mice following chronic inhalation at vapor concentrations which were cytotoxic." | 2.37 | An analysis of potential carcinogenic risk from formaldehyde. ( Cameron, LL; Squire, RA, 1984) |
" These values are presented as a best estimate envelope obtained from five mathematical dose-response formulation." | 2.37 | Risk assessment of laboratory rats and mice chronically exposed to formaldehyde vapors. ( Brown, KG, 1985) |
" Dose-response predictions below the range of exposures where tumors occurred in the bioassays were highly sensitive to the choice of control data." | 1.34 | Uncertainties in the CIIT model for formaldehyde-induced carcinogenicity in the rat: a limited sensitivity analysis-I. ( Chen, C; Crump, KS; Schlosser, PM; Subramaniam, RP; Van Landingham, C; White, P, 2007) |
" Two methods for dose-response assessment were used: a full biologically based modeling approach and a statistically oriented analysis by benchmark dose (BMD) method." | 1.32 | Benchmark dose risk assessment for formaldehyde using airflow modeling and a single-compartment, DNA-protein cross-link dosimetry model to estimate human equivalent doses. ( Conolly, RB; Janszen, DB; Kimbell, JS; Lilly, PD; Schlosser, PM, 2003) |
" The direct mutagenicity mode of action was represented by a low dose linear dose-response model of DNA-protein cross-link (DPX) formation." | 1.32 | Biologically motivated computational modeling of formaldehyde carcinogenicity in the F344 rat. ( Conolly, RB; Janszen, D; Kalisak, D; Kimbell, JS; Miller, FJ; Preston, J; Schlosser, PM, 2003) |
" 75, 432-447, 2003) analyzed the rat tumor dose-response assuming that both DNA-reactive and cytotoxic effects of formaldehyde contribute to SCC development." | 1.32 | Human respiratory tract cancer risks of inhaled formaldehyde: dose-response predictions derived from biologically-motivated computational modeling of a combined rodent and human dataset. ( Conolly, RB; Janszen, D; Kalisak, D; Kimbell, JS; Miller, FJ; Preston, J; Schlosser, PM, 2004) |
"Formaldehyde (FA) is a mutagen that, at high concentrations and long durations, has been reported to cause nasal cancer in rats and in some humans." | 1.32 | Formaldehyde-induced DNA adducts as biomarkers of in vitro human nasal epithelial cell exposure to formaldehyde. ( Que Hee, SS; Zhong, W, 2004) |
"Elevated rates of nasal and nasopharyngeal cancers have been associated with wood-related occupational exposures, including chlorophenols, formaldehyde, and wood dust." | 1.31 | Occupational exposure to chlorophenol and the risk of nasal and nasopharyngeal cancers among U.S. men aged 30 to 60. ( Brann, EA; Gnepp, DR; Herrick, RF; Hoppin, JA; Mirabelli, MC; Tolbert, PE, 2000) |
"For sino-nasal cancer, a relative risk of 3." | 1.29 | Formaldehyde and cancer morbidity among male employees in Denmark. ( Hansen, J; Olsen, JH, 1995) |
"A case-control study of cancer of the nose and paranasal sinuses was conducted in France to determine whether occupational exposure to formaldehyde was associated with an increased risk of sinonasal cancer." | 1.29 | Sinonasal cancer and occupational exposure to formaldehyde and other substances. ( Brugère, J; Gérin, M; Goldberg, M; Leclerc, A; Luce, D; Morcet, JF, 1993) |
"Formaldehyde (FA) is a widely produced industrial chemical." | 1.29 | DNA--protein crosslinks, a biomarker of exposure to formaldehyde--in vitro and in vivo studies. ( Bomstein, Y; Kaufman, Z; Meltzer, A; Palma, E; Ribak, J; Shaham, J, 1996) |
"Formaldehyde induces squamous cell carcinomas in the nasal passages of rats following chronic inhalation exposure at concentrations of > or = 10 ppm." | 1.28 | p53 mutations in formaldehyde-induced nasal squamous cell carcinomas in rats. ( Bermudez, E; Chen, Z; Gross, EA; Morgan, K; Pluta, L; Recio, L; Sisk, S; Walker, C, 1992) |
"Formaldehyde is a well known nasal carcinogen in rodents, but so far there has been no convincing evidence that workers occupationally exposed to formaldehyde have an increased risk of nasal cancer." | 1.28 | Malignant melanomas of the nasal cavity after occupational exposure to formaldehyde. ( Holmstrom, M; Lund, VJ, 1991) |
"No deaths from nasal cancer were reported (1." | 1.27 | Formaldehyde in the British chemical industry. An occupational cohort study. ( Acheson, ED; Barnes, HR; Gardner, MJ; Osmond, C; Pannett, B; Taylor, CP, 1984) |
"The excess risk of sino-nasal cancer with exposure to paint, lacquer and glue remained statistically elevated after adjustment for contemporary exposure to wood-dust and formaldehyde." | 1.27 | Occupational formaldehyde exposure and increased nasal cancer risk in man. ( Breum, NO; Faurbo, K; Hink, M; Jensen, OM; Jensen, SP; Olsen, JH, 1984) |
"A case of squamous cell carcinoma of the nasal cavity occurred in a 57-year-old man who had 25 years of occupational exposure to low concentrations of formaldehyde in the textile-finishing industry." | 1.27 | Nasal cancer in a worker exposed to formaldehyde. ( Elliott, LJ; Goodman, M; Halperin, WE; Keenlyside, RA; Landrigan, PJ; Stayner, L, 1983) |
"Formaldehyde inhalation was also weakly associated with an increase in the frequency of polypoid adenomas in the nasal cavity of male rats." | 1.27 | Carcinogenicity of formaldehyde in rats and mice after long-term inhalation exposure. ( Donofrio, DJ; Gralla, EJ; Kerns, WD; Pavkov, KL; Swenberg, JA, 1983) |
"Recent animal studies found nasal cancer among rats exposed to formaldehyde, but no excess of this tumor occurred in this study." | 1.27 | Mortality among industrial workers exposed to formaldehyde. ( Bales, R; Blair, A; Cubit, D; Gaffey, W; Kaplan, S; O'Berg, M; Stewart, P; Walrath, J; Ward, J, 1986) |
"Population-based rates for sinonasal cancer are examined in US mortality data among whites and in Connecticut incidence data." | 1.27 | Time and age trends for sinonasal cancer in Connecticut incidence and US mortality rates. ( Holford, TR; Roush, GC; Schymura, MJ; Stevenson, JM, 1987) |
"The majority of squamous cell carcinomas occurred on the anterior portion of the lateral aspect of the nasoturbinate and adjacent lateral wall (57%) or the midventral nasal septum (26%)." | 1.27 | More precise localization of nasal tumors associated with chronic exposure of F-344 rats to formaldehyde gas. ( Jiang, XZ; Kerns, WD; Morgan, KT; Starr, TB, 1986) |
"By Assessment A the relative risk for nasal cancer associated with possible formaldehyde exposure was 2." | 1.27 | Cancer of the nasal cavity and paranasal sinuses, and formaldehyde exposure. ( de Bruyn, A; Gerin, M; Hayes, RB; Raatgever, JW, 1986) |
"The results from employing metabolized dose in the case of vinyl chloride demonstrate that the delivered dose concept can radically alter the shape of the dose-response curve in the observable response range." | 1.27 | The role of mechanistic data in dose-response modeling. ( Starr, TB, 1985) |
"Inhalation of formaldehyde causes cancer of the nose in rats." | 1.26 | Report of the Federal Panel on Formaldehyde. ( , 1982) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 42 (51.85) | 18.7374 |
1990's | 23 (28.40) | 18.2507 |
2000's | 11 (13.58) | 29.6817 |
2010's | 4 (4.94) | 24.3611 |
2020's | 1 (1.23) | 2.80 |
Authors | Studies |
---|---|
Thompson, CM | 1 |
Gentry, R | 1 |
Fitch, S | 1 |
Lu, K | 2 |
Clewell, HJ | 2 |
Crump, KS | 2 |
Chen, C | 2 |
Fox, JF | 1 |
Van Landingham, C | 2 |
Subramaniam, R | 1 |
Flohr, C | 1 |
Lee, KK | 1 |
Varma, S | 1 |
Collins, LB | 1 |
Ru, H | 1 |
Bermudez, E | 4 |
Swenberg, JA | 4 |
Yang, Y | 1 |
Allen, BC | 1 |
Tan, YM | 1 |
Liao, KH | 1 |
Nielsen, GD | 1 |
Wolkoff, P | 1 |
Lutz, RW | 1 |
Stahel, WA | 1 |
Lutz, WK | 1 |
Schlosser, PM | 4 |
Lilly, PD | 1 |
Conolly, RB | 3 |
Janszen, DB | 1 |
Kimbell, JS | 4 |
Janszen, D | 2 |
Kalisak, D | 2 |
Preston, J | 2 |
Miller, FJ | 2 |
Zhong, W | 1 |
Que Hee, SS | 1 |
Meek, ME | 1 |
Arts, JH | 1 |
Rennen, MA | 1 |
de Heer, C | 1 |
Subramaniam, RP | 1 |
White, P | 1 |
Kupczewska-Dobecka, M | 1 |
Jensen, OM | 2 |
Acheson, ED | 3 |
Barnes, HR | 2 |
Gardner, MJ | 3 |
Osmond, C | 2 |
Pannett, B | 3 |
Taylor, CP | 2 |
Casanova-Schmitz, M | 1 |
Starr, TB | 6 |
Heck, HD | 2 |
Squire, RA | 1 |
Cameron, LL | 1 |
Koenig, JQ | 1 |
Pierson, WE | 1 |
L'Abbé, KA | 1 |
Hoey, JR | 1 |
Ballenger, JJ | 1 |
Olsen, JH | 3 |
Jensen, SP | 1 |
Hink, M | 1 |
Faurbo, K | 1 |
Breum, NO | 1 |
Frazier, TM | 1 |
Lalich, NR | 1 |
Pedersen, DH | 1 |
Kreiger, N | 1 |
Halperin, WE | 1 |
Goodman, M | 1 |
Stayner, L | 1 |
Elliott, LJ | 1 |
Keenlyside, RA | 1 |
Landrigan, PJ | 1 |
Kerns, WD | 3 |
Pavkov, KL | 2 |
Donofrio, DJ | 1 |
Gralla, EJ | 3 |
Albert, RE | 1 |
Sellakumar, AR | 1 |
Laskin, S | 1 |
Kuschner, M | 1 |
Nelson, N | 1 |
Snyder, CA | 1 |
Swenberg, J | 1 |
Kerns, W | 1 |
Pavkov, K | 1 |
Mitchell, R | 1 |
Mitchell, RI | 1 |
Wilbourn, J | 1 |
Heseltine, E | 1 |
Møller, H | 1 |
Hansen, J | 1 |
Wolf, DC | 1 |
Gross, EA | 5 |
Lyght, O | 1 |
Recio, L | 4 |
Morgan, KT | 6 |
McMillan, A | 1 |
Whittemore, AS | 1 |
Silvers, A | 1 |
DiCiccio, Y | 1 |
Monticello, TM | 3 |
Luce, D | 2 |
Gérin, M | 3 |
Berrino, F | 1 |
Pisani, P | 1 |
Leclerc, A | 2 |
Chen, Z | 2 |
Walker, CL | 1 |
Pluta, L | 2 |
Goldoft, M | 1 |
Weiss, N | 1 |
Vaughan, T | 1 |
Lee, J | 1 |
Winter, PD | 1 |
Cruddas, AM | 1 |
Morcet, JF | 1 |
Brugère, J | 1 |
Goldberg, M | 1 |
Shaham, J | 1 |
Bomstein, Y | 1 |
Meltzer, A | 1 |
Kaufman, Z | 1 |
Palma, E | 1 |
Ribak, J | 1 |
Leininger, JR | 1 |
Seilkop, S | 1 |
Gibson, JE | 2 |
Reed, C | 1 |
Kamata, E | 1 |
Nakadate, M | 1 |
Uchida, O | 1 |
Ogawa, Y | 1 |
Suzuki, S | 1 |
Kaneko, T | 1 |
Saito, M | 1 |
Kurokawa, Y | 1 |
Blair, A | 4 |
Kazerouni, N | 1 |
Mirabelli, MC | 1 |
Hoppin, JA | 1 |
Tolbert, PE | 1 |
Herrick, RF | 1 |
Gnepp, DR | 1 |
Brann, EA | 1 |
Judge, DM | 1 |
McGavran, MH | 1 |
Trapukdi, S | 1 |
Sisk, S | 1 |
Morgan, K | 1 |
Walker, C | 1 |
Holmstrom, M | 1 |
Lund, VJ | 1 |
Fellbaum, C | 1 |
Hansmann, ML | 1 |
Saracci, R | 1 |
Stewart, PA | 1 |
Hayes, RB | 2 |
Shy, C | 1 |
Boysen, M | 1 |
Zadig, E | 1 |
Digernes, V | 1 |
Abeler, V | 1 |
Reith, A | 1 |
Woutersen, RA | 2 |
van Garderen-Hoetmer, A | 2 |
Bruijntjes, JP | 1 |
Zwart, A | 1 |
Feron, VJ | 2 |
Brandwein, M | 1 |
Pervez, N | 1 |
Biller, H | 1 |
Stewart, P | 1 |
O'Berg, M | 1 |
Gaffey, W | 1 |
Walrath, J | 2 |
Ward, J | 1 |
Bales, R | 1 |
Kaplan, S | 1 |
Cubit, D | 1 |
Roush, GC | 2 |
Stayner, LT | 1 |
Kaplan, SA | 1 |
Flannery, JT | 1 |
Norman, GR | 1 |
Newhouse, MT | 1 |
Schymura, MJ | 1 |
Stevenson, JM | 1 |
Holford, TR | 1 |
Edling, C | 2 |
Hellquist, H | 2 |
Odkvist, L | 2 |
Lam, CW | 1 |
Casanova, M | 1 |
Zielhuis, RL | 1 |
Krimsky, MM | 1 |
Appelman, LM | 1 |
Asnaes, S | 1 |
Casteel, SW | 1 |
Vernon, RJ | 1 |
Bailey, EM | 1 |
Rosskamp, E | 1 |
Stankevich, KI | 1 |
Dyshinevich, NE | 1 |
Brown, KG | 1 |
Jiang, XZ | 1 |
Raatgever, JW | 1 |
de Bruyn, A | 1 |
Gardner, RJ | 1 |
Burgess, BA | 1 |
Kennedy, GL | 1 |
Flamm, WG | 1 |
Frankos, V | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Environmental and Genetic Determinants of NPC[NCT01257100] | 3,500 participants (Actual) | Observational | 2010-12-08 | Terminated (stopped due to Determined not to be Human Subject Research) | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
18 reviews available for formaldehyde and Cancer of Nose
Article | Year |
---|---|
An updated mode of action and human relevance framework evaluation for Formaldehyde-Related nasal tumors.
Topics: Animals; Carcinogens; DNA Adducts; DNA Damage; Formaldehyde; Humans; Nose Neoplasms; Rats; Risk Asse | 2020 |
Cancer effects of formaldehyde: a proposal for an indoor air guideline value.
Topics: Air Pollution, Indoor; Animals; Carcinogens; Dose-Response Relationship, Drug; Environmental Exposur | 2010 |
Inhaled formaldehyde: evaluation of sensory irritation in relation to carcinogenicity.
Topics: Administration, Inhalation; Air Pollutants; Animals; Carcinogens; Carcinoma; Eye; Formaldehyde; Huma | 2006 |
[Assessment of carcinogenicity of formaldehyde based on the newest literature data].
Topics: Air Pollutants; Animals; Carcinogenicity Tests; Carcinogens; European Union; Formaldehyde; Humans; I | 2007 |
An analysis of potential carcinogenic risk from formaldehyde.
Topics: Aerosols; Animals; Biological Assay; Carcinogens, Environmental; Epidemiologic Methods; Formaldehyde | 1984 |
Nasal responses to air pollutants.
Topics: Air Pollutants; Air Pollutants, Occupational; Airway Resistance; Chromates; Cilia; Formaldehyde; Hum | 1984 |
Review of the health effects of urea-formaldehyde foam insulation.
Topics: Abnormalities, Drug-Induced; Adult; Air Pollutants; Animals; Construction Materials; Dermatitis, Con | 1984 |
Cell proliferation and nasal carcinogenesis.
Topics: Animals; Carcinogens; Cell Division; DNA; Formaldehyde; Humans; Kinetics; Nasal Cavity; Nitrosamines | 1993 |
Cell proliferation and formaldehyde-induced respiratory carcinogenesis.
Topics: Animals; Cell Division; Dose-Response Relationship, Drug; Formaldehyde; Male; Nose; Nose Neoplasms; | 1994 |
Oncogene and tumor suppressor gene alterations in nasal tumors.
Topics: Animals; Carcinoma, Squamous Cell; Formaldehyde; Genes, p53; Genes, Tumor Suppressor; Mutation; Nose | 1997 |
Reactive chemicals and cancer.
Topics: Acrylonitrile; Air Pollutants; Animals; Bis(Chloromethyl) Ether; Butadienes; Carcinogens; Cohort Stu | 1997 |
Quantitative cancer risk estimation for formaldehyde.
Topics: Air Pollutants; Animals; Dose-Response Relationship, Drug; Epidemiologic Factors; Formaldehyde; Huma | 1990 |
Epidemiologic evidence on the relationship between formaldehyde exposure and cancer.
Topics: Brain Neoplasms; Colorectal Neoplasms; Environmental Exposure; Formaldehyde; Humans; Leukemia; Lung | 1990 |
Nasal squamous carcinoma in an undertaker--does formaldehyde play a role?
Topics: Carcinoma, Squamous Cell; Embalming; Formaldehyde; Humans; Male; Middle Aged; Nose Neoplasms; Occupa | 1987 |
Health effects of urea formaldehyde foam insulation: evidence of causation.
Topics: Air Pollutants; Formaldehyde; Housing; Humans; Nose Neoplasms; Respiratory Tract Diseases; Urea | 1986 |
The mechanistic toxicology of formaldehyde and its implications for quantitative risk estimation.
Topics: Air Pollutants; Animals; Cell Division; Formaldehyde; Humans; Irritants; Mice; Mucous Membrane; Nose | 1985 |
[Hygienic aspects of using wood-shaving boards in the construction of residential and commercial buildings].
Topics: Adenocarcinoma; Air Pollutants; Air Pollution; Allergens; Animals; Construction Materials; Europe; F | 1985 |
Risk assessment of laboratory rats and mice chronically exposed to formaldehyde vapors.
Topics: Animals; Carcinoma, Squamous Cell; Female; Formaldehyde; Male; Mice; Nasal Cavity; Nose Neoplasms; R | 1985 |
63 other studies available for formaldehyde and Cancer of Nose
Article | Year |
---|---|
Sensitivity analysis of biologically motivated model for formaldehyde-induced respiratory cancer in humans.
Topics: Animals; Cell Transformation, Neoplastic; Disease Models, Animal; Formaldehyde; Humans; Models, Biol | 2008 |
Merocel nasal packing with airway: a method to help secure full-thickness skin grafts on the nasal tip.
Topics: Formaldehyde; Humans; Nasal Obstruction; Nose; Nose Neoplasms; Polyvinyl Alcohol; Rhinoplasty; Skin | 2010 |
Distribution of DNA adducts caused by inhaled formaldehyde is consistent with induction of nasal carcinoma but not leukemia.
Topics: Animals; Chromatography, High Pressure Liquid; DNA Adducts; Formaldehyde; Inhalation Exposure; Leuke | 2010 |
Bayesian analysis of a rat formaldehyde DNA-protein cross-link model.
Topics: Animals; Bayes Theorem; Cross-Linking Reagents; Disease Models, Animal; DNA; DNA Damage; Formaldehyd | 2010 |
Statistical procedures to test for linearity and estimate threshold doses for tumor induction with nonlinear dose-response relationships in bioassays for carcinogenicity.
Topics: Adenocarcinoma; Animals; Biological Assay; Carcinogenicity Tests; Carcinogens; Disinfectants; Dose-R | 2002 |
Benchmark dose risk assessment for formaldehyde using airflow modeling and a single-compartment, DNA-protein cross-link dosimetry model to estimate human equivalent doses.
Topics: Administration, Inhalation; Air Pollutants; Animals; Carcinoma, Squamous Cell; Cross-Linking Reagent | 2003 |
Biologically motivated computational modeling of formaldehyde carcinogenicity in the F344 rat.
Topics: Administration, Inhalation; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Division; Computati | 2003 |
Human respiratory tract cancer risks of inhaled formaldehyde: dose-response predictions derived from biologically-motivated computational modeling of a combined rodent and human dataset.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Computational Biology; Dose-Response Relationship, D | 2004 |
Formaldehyde-induced DNA adducts as biomarkers of in vitro human nasal epithelial cell exposure to formaldehyde.
Topics: Animals; Biomarkers; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; DNA Adduc | 2004 |
Biologically motivated computational modeling: contribution to risk assessment.
Topics: Administration, Inhalation; Animals; Carcinogens; Computational Biology; Formaldehyde; Humans; Model | 2004 |
Uncertainties in the CIIT model for formaldehyde-induced carcinogenicity in the rat: a limited sensitivity analysis-I.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Division; Cocarcinogenesis; Cross-Linking Reage | 2007 |
Cancer risk from formaldehyde.
Topics: Aged; Animals; Formaldehyde; Humans; Middle Aged; Neoplasms; Nose Neoplasms; Rats; Risk | 1980 |
Formaldehyde in the British chemical industry. An occupational cohort study.
Topics: Chemical Industry; England; Environmental Exposure; Formaldehyde; Humans; Lung Neoplasms; Male; Nose | 1984 |
Cohort study of formaldehyde process workers.
Topics: Animals; Formaldehyde; Humans; Lung Neoplasms; Male; Nose Neoplasms; Occupational Diseases; Rats | 1984 |
Differentiation between metabolic incorporation and covalent binding in the labeling of macromolecules in the rat nasal mucosa and bone marrow by inhaled [14C]- and [3H]formaldehyde.
Topics: Animals; Bone Marrow; DNA; Formaldehyde; Male; Nose Neoplasms; Proteins; Rats; Rats, Inbred F344; RN | 1984 |
Some effects of formaldehyde on the upper respiratory tract.
Topics: Air Pollutants; Animals; Formaldehyde; Haplorhini; Housing; Humans; Male; Mice; Middle Aged; Nasal M | 1984 |
Occupational formaldehyde exposure and increased nasal cancer risk in man.
Topics: Air Pollutants, Occupational; Denmark; Dust; Formaldehyde; Humans; Male; Nose Neoplasms; Occupationa | 1984 |
Uses of computer-generated maps in occupational hazard and mortality surveillance.
Topics: Aged; Computers; Environmental Exposure; Formaldehyde; Humans; Male; Maps as Topic; Mortality; Natio | 1983 |
Formaldehyde and nasal cancer mortality.
Topics: Animals; Formaldehyde; Humans; Nose Neoplasms; Occupational Diseases; Rats; Rats, Inbred Strains | 1983 |
Nasal cancer in a worker exposed to formaldehyde.
Topics: Carcinoma, Squamous Cell; Formaldehyde; Humans; Male; Middle Aged; Nasal Cavity; Nose Neoplasms; Occ | 1983 |
Carcinogenicity of formaldehyde in rats and mice after long-term inhalation exposure.
Topics: Animals; Body Weight; Carcinogens; Dose-Response Relationship, Drug; Female; Formaldehyde; Male; Mic | 1983 |
Gaseous formaldehyde and hydrogen chloride induction of nasal cancer in the rat.
Topics: Animals; Bis(Chloromethyl) Ether; Body Weight; Drug Interactions; Formaldehyde; Gases; Humans; Hydro | 1982 |
Report of the Federal Panel on Formaldehyde.
Topics: Abnormalities, Drug-Induced; Adult; Animals; Chemical Phenomena; Chemistry; Cross-Sectional Studies; | 1982 |
Carcinogenicity of formaldehyde vapor: interim findings in a long-term bioassay of rats and mice.
Topics: Animals; Carcinogens, Environmental; Carcinoma, Squamous Cell; Female; Formaldehyde; Male; Mice; Neo | 1980 |
Induction of squamous cell carcinomas of the rat nasal cavity by inhalation exposure to formaldehyde vapor.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Environmental Expo | 1980 |
IARC evaluates wood dust and formaldehyde. International Agency for Research on Cancer.
Topics: Animals; Case-Control Studies; Dust; Formaldehyde; Humans; Nose Neoplasms; Occupational Diseases; Ri | 1995 |
Formaldehyde and cancer morbidity among male employees in Denmark.
Topics: Adult; Aged; Aged, 80 and over; Denmark; Formaldehyde; Humans; Male; Middle Aged; Neoplasms; Nose Ne | 1995 |
Immunohistochemical localization of p53, PCNA, and TGF-alpha proteins in formaldehyde-induced rat nasal squamous cell carcinomas.
Topics: Animals; Carcinoma, Squamous Cell; Formaldehyde; Immunoenzyme Techniques; Male; Nose Neoplasms; Prol | 1995 |
Use of biological markers in risk assessment.
Topics: Animals; Biological Assay; Biomarkers; Biomarkers, Tumor; Carcinoma, Squamous Cell; Formaldehyde; Hu | 1994 |
Sources of discrepancies between a job exposure matrix and a case by case expert assessment for occupational exposure to formaldehyde and wood-dust.
Topics: Case-Control Studies; Dust; Formaldehyde; Humans; Laryngeal Neoplasms; Methods; Nose Neoplasms; Occu | 1993 |
Characterization of cell lines derived from formaldehyde-induced nasal tumors in rats.
Topics: Animals; Carcinoma; Cell Line; Female; Formaldehyde; Gene Expression Regulation, Neoplastic; Genes, | 1994 |
Nasal melanoma.
Topics: Formaldehyde; Humans; Melanoma; Nose Neoplasms; Occupational Diseases; Occupational Exposure | 1993 |
A cohort study of workers exposed to formaldehyde in the British chemical industry: an update.
Topics: Chemical Industry; Cohort Studies; Follow-Up Studies; Formaldehyde; Humans; Lung Neoplasms; Male; Ne | 1993 |
Sinonasal cancer and occupational exposure to formaldehyde and other substances.
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Dust; Female; Formaldehyde; France; Humans; Male; Nose Neo | 1993 |
DNA--protein crosslinks, a biomarker of exposure to formaldehyde--in vitro and in vivo studies.
Topics: Biomarkers; Carcinogens; Carcinoma, Squamous Cell; DNA; Formaldehyde; Humans; Leukocytes; Nose Neopl | 1996 |
Correlation of regional and nonlinear formaldehyde-induced nasal cancer with proliferating populations of cells.
Topics: Animals; Carcinoma, Squamous Cell; Cell Division; Dose-Response Relationship, Drug; Formaldehyde; Ma | 1996 |
Follow your nose.
Topics: Animals; Carcinoma, Squamous Cell; Formaldehyde; Nose Neoplasms; Rats | 1996 |
Results of a 28-month chronic inhalation toxicity study of formaldehyde in male Fisher-344 rats.
Topics: Administration, Inhalation; Animals; Body Weight; Dose-Response Relationship, Drug; Eating; Formalde | 1997 |
Occupational exposure to chlorophenol and the risk of nasal and nasopharyngeal cancers among U.S. men aged 30 to 60.
Topics: Adult; Case-Control Studies; Chlorophenols; Confidence Intervals; Confounding Factors, Epidemiologic | 2000 |
Fume-induced fluorescence in diagnosis of nasal neuroblastoma.
Topics: Formaldehyde; Humans; Microscopy, Electron; Microscopy, Fluorescence; Neuroectodermal Tumors, Primit | 1976 |
p53 mutations in formaldehyde-induced nasal squamous cell carcinomas in rats.
Topics: Animals; Base Sequence; Carcinoma, Squamous Cell; DNA, Neoplasm; Formaldehyde; Genes, p53; Molecular | 1992 |
Malignant melanomas of the nasal cavity after occupational exposure to formaldehyde.
Topics: Aged; Female; Formaldehyde; Humans; Melanoma; Middle Aged; Nasal Mucosa; Nose Neoplasms; Occupationa | 1991 |
Immunohistochemical differential diagnosis of granulocytic sarcomas and malignant lymphomas on formalin-fixed material.
Topics: Child; Diagnosis, Differential; Female; Fixatives; Formaldehyde; Humans; Immunohistochemistry; Leuke | 1990 |
Nasal mucosa in workers exposed to formaldehyde: a pilot study.
Topics: Adult; Aged; Chemical Industry; Formaldehyde; Humans; Middle Aged; Nasal Mucosa; Nose Neoplasms; Occ | 1990 |
Nasal tumours in rats after severe injury to the nasal mucosa and prolonged exposure to 10 ppm formaldehyde.
Topics: Animals; Body Weight; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Electrocoagulation | 1989 |
Mortality among industrial workers exposed to formaldehyde.
Topics: Adult; Environmental Exposure; Female; Formaldehyde; Hodgkin Disease; Humans; Industry; Leukemia; Lu | 1986 |
Nasopharyngeal cancer, sinonasal cancer, and occupations related to formaldehyde: a case-control study.
Topics: Formaldehyde; Humans; Male; Nasopharyngeal Neoplasms; Nose Neoplasms; Occupational Diseases; Paranas | 1987 |
Time and age trends for sinonasal cancer in Connecticut incidence and US mortality rates.
Topics: Age Factors; Connecticut; Female; Formaldehyde; Humans; Male; Nose Neoplasms; Paranasal Sinus Neopla | 1987 |
Occupational formaldehyde exposure and the nasal mucosa.
Topics: Adult; Aged; Formaldehyde; Humans; Metaplasia; Middle Aged; Nasal Mucosa; Nose Diseases; Nose Neopla | 1987 |
Decreased extractability of DNA from proteins in the rat nasal mucosa after acetaldehyde exposure.
Topics: Acetaldehyde; Animals; Cross-Linking Reagents; DNA; Dose-Response Relationship, Drug; Formaldehyde; | 1986 |
[Hobby and occupation as causes of cancer].
Topics: Adult; Azo Compounds; Coloring Agents; Female; Formaldehyde; Hobbies; Humans; Male; Neoplasms; Nose | 1986 |
Induction of nasal tumors in rats exposed to mixtures of hydrochloric acid (HCl) and formaldehyde (HCHO) by inhalation.
Topics: Administration, Inhalation; Animals; Bis(Chloromethyl) Ether; Formaldehyde; Hydrochloric Acid; Methy | 1986 |
Inhalation toxicity of acetaldehyde in rats. III. Carcinogenicity study.
Topics: Acetaldehyde; Adenocarcinoma; Administration, Inhalation; Animals; Body Weight; Carcinoma, Squamous | 1986 |
Formaldehyde and the risk of squamous cell carcinoma of the sinonasal cavities.
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Denmark; Female; Formaldehyde; Humans; Male; Nasopharyngea | 1986 |
Formaldehyde: toxicology and hazards.
Topics: Air Pollutants; Animals; Formaldehyde; Humans; Nose Neoplasms; Respiratory Tract Diseases; Skin Dise | 1987 |
[The environment and cancer].
Topics: Animals; Asbestos; Carcinogens, Environmental; Carcinoma, Squamous Cell; Formaldehyde; Humans; Lung | 1985 |
More precise localization of nasal tumors associated with chronic exposure of F-344 rats to formaldehyde gas.
Topics: Animals; Carcinoma, Squamous Cell; Female; Formaldehyde; Gases; Male; Nasal Polyps; Nose; Nose Neopl | 1986 |
Cancer of the nasal cavity and paranasal sinuses, and formaldehyde exposure.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Dust; Formaldehyde; Humans; Male; Middle Aged | 1986 |
Formaldehyde and the nasal mucosa.
Topics: Adult; Formaldehyde; Humans; Male; Middle Aged; Nasal Mucosa; Nose Neoplasms; Occupational Diseases; | 1985 |
Sensory irritation potential of selected nasal tumorigens in the rat.
Topics: Animals; Carcinogens; Epichlorohydrin; Formaldehyde; Gases; Hempa; Hydrocarbons, Chlorinated; Irrita | 1985 |
The role of mechanistic data in dose-response modeling.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Division; Dose-Response Relationship, Drug; For | 1985 |
Formaldehyde: laboratory evidence.
Topics: Animals; Carcinoma, Squamous Cell; Cricetinae; Female; Formaldehyde; Male; Mice; Nose Neoplasms; Rab | 1985 |
Formaldehyde: epidemiological evidence.
Topics: Formaldehyde; Humans; Male; Neoplasms; Nose Neoplasms; Occupational Diseases | 1985 |