formaldehyde has been researched along with Cancer of Head in 27 studies
paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy
| Excerpt | Relevance | Reference |
|---|---|---|
| "A possible relationship between exposure to formaldehyde and leukemia-particularly myeloid leukemia-as well as of lymphoid neoplasms has been debated and is still controversial." | 3.80 | Mortality from lymphohematopoietic neoplasms and other causes in a cohort of laminated plastic workers exposed to formaldehyde. ( La Vecchia, C; Pira, E; Romano, C; Verga, F, 2014) |
| "In formalin-fixed paraffin-embedded HNSCCs, NRF2 signaling intensity positively correlated with NRF2-activating mutations and with SOX2 protein expression." | 1.91 | Targeted Proteomic Quantitation of NRF2 Signaling and Predictive Biomarkers in HNSCC. ( Gerndt, SP; Gilmore, PE; Goldfarb, D; Guan, L; Holmes, BJ; Jackson, RS; LaPak, KM; Le, QT; Major, MB; Paniello, RC; Pipkorn, P; Puram, SV; Rich, JT; Schrank, TP; Sprung, RW; Townsend, RR; Wamsley, NT; Wilkerson, EM; Zevallos, JP; Zolkind, P, 2023) |
| "Head and neck cancers (HNCs) are a heterogeneous group of tumors that progress owing to varied enviromental and genetic risk factors." | 1.72 | Human papillomavirus, tobacco, and poor oral hygiene can act synergetically, modulate the expression of the nuclear factor kappa B signaling pathway for the development and progression of head and neck cancer in the Pakistani population. ( Malik, SA; Mulla, M; Sabir, M; Sarwar, S; Sultan, A; Tanveer, R, 2022) |
| "To determine genomic alterations in head and neck squamous cell carcinoma (HNSCC) using formalin-fixed, paraffin-embedded (FFPE) tumors obtained through routine clinical practice, selected cancer-related genes were evaluated and compared with alterations seen in frozen tumors obtained through research studies." | 1.42 | Genomic alterations in head and neck squamous cell carcinoma determined by cancer gene-targeted sequencing. ( Agrawal, N; Ali, SM; Bishop, JA; Chalmers, ZR; Chung, CH; Fakhry, C; Frampton, GM; Guthrie, VB; Kang, H; Karchin, R; Masica, DL; Miller, VA; Quon, H; Richmon, J; Seiwert, T; Stephens, PJ; Subramaniam, RM; Tokheim, C; Yelensky, R; Zuo, Z, 2015) |
| "We found that head and neck cancer specimens shrink after formalin fixation." | 1.38 | Shrinkage of head and neck cancer specimens after formalin fixation. ( Chen, CH; Chen, FJ; Hsu, MY; Jiang, RS; Liu, SA; Wu, SH, 2012) |
| "When mannose was added to the co-cultures, monocyte IL-6 mRNA expression was eradicated in malignant co-cultures and reduced to a low level in benign co-cultures." | 1.31 | Mechanisms for monocyte activation in co-culture with autologous tumor spheroids. ( Aarstad, HJ; Heimdal, JH; Kross, K; Olofsson, J; Olsnes, C, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (7.41) | 18.2507 |
| 2000's | 1 (3.70) | 29.6817 |
| 2010's | 14 (51.85) | 24.3611 |
| 2020's | 10 (37.04) | 2.80 |
| Authors | Studies |
|---|---|
| Olsnes, C | 1 |
| Heimdal, JH | 1 |
| Kross, K | 1 |
| Olofsson, J | 1 |
| Aarstad, HJ | 1 |
| Paytubi, S | 1 |
| Taberna, M | 1 |
| Mena, M | 1 |
| Quirós, B | 1 |
| Gomà, M | 1 |
| Alemany, L | 1 |
| Bosch, FX | 1 |
| Pavón, MÁ | 1 |
| Doonan, K | 1 |
| Ambaye, A | 1 |
| Buskey, A | 1 |
| Mitchell, J | 1 |
| Ciolino, AL | 1 |
| Kamat, MS | 1 |
| Puranik, RS | 1 |
| Das Rai, AB | 1 |
| Patil, BR | 1 |
| Patil, S | 1 |
| Dressler, FF | 1 |
| Dabadghao, DS | 1 |
| Klapper, L | 1 |
| Perner, S | 1 |
| Idel, C | 1 |
| Ribbat-Idel, J | 1 |
| Sarwar, S | 1 |
| Mulla, M | 2 |
| Tanveer, R | 1 |
| Sabir, M | 1 |
| Sultan, A | 1 |
| Malik, SA | 1 |
| K, K | 1 |
| Kamboj, V | 1 |
| Sreedharan, S | 1 |
| S, VS | 1 |
| Rai, T | 1 |
| Kabekkodu, S | 1 |
| Wamsley, NT | 1 |
| Wilkerson, EM | 1 |
| Guan, L | 1 |
| LaPak, KM | 1 |
| Schrank, TP | 1 |
| Holmes, BJ | 1 |
| Sprung, RW | 1 |
| Gilmore, PE | 1 |
| Gerndt, SP | 1 |
| Jackson, RS | 1 |
| Paniello, RC | 1 |
| Pipkorn, P | 1 |
| Puram, SV | 1 |
| Rich, JT | 1 |
| Townsend, RR | 1 |
| Zevallos, JP | 1 |
| Zolkind, P | 1 |
| Le, QT | 1 |
| Goldfarb, D | 1 |
| Major, MB | 1 |
| Buonocore, DJ | 1 |
| Fowle, E | 1 |
| Lin, O | 1 |
| Xu, B | 1 |
| Katabi, N | 1 |
| Cohen, JM | 1 |
| Kapoor, S | 1 |
| Lu, G | 1 |
| van den Berg, NS | 1 |
| Krishnan, G | 1 |
| Pei, J | 1 |
| Zhou, Q | 1 |
| Martin, BA | 1 |
| Baik, FM | 1 |
| Rosenthal, EL | 1 |
| Nishio, N | 1 |
| Ling, J | 1 |
| Chang, A | 1 |
| Ye, H | 1 |
| Zhao, H | 1 |
| Zhuo, X | 1 |
| Stepp, WH | 1 |
| Desai, KM | 1 |
| Angadi, PV | 1 |
| Kale, AD | 1 |
| Hallikerimath, S | 1 |
| Huho, AN | 1 |
| Yadak, N | 1 |
| Bocklage, TJ | 1 |
| Yang, S | 1 |
| Mori, T | 1 |
| Kobayashi, K | 1 |
| Yoshimoto, S | 1 |
| Lal, A | 1 |
| Panos, R | 1 |
| Marjanovic, M | 1 |
| Walker, M | 1 |
| Fuentes, E | 1 |
| Kubicek, GJ | 1 |
| Henner, WD | 1 |
| Buturovic, LJ | 1 |
| Halks-Miller, M | 1 |
| Ross, JS | 1 |
| Wang, K | 1 |
| Rand, JV | 1 |
| Sheehan, CE | 1 |
| Jennings, TA | 1 |
| Al-Rohil, RN | 1 |
| Otto, GA | 1 |
| Curran, JC | 1 |
| Palmer, G | 1 |
| Downing, SR | 1 |
| Yelensky, R | 2 |
| Lipson, D | 1 |
| Balasubramanian, S | 1 |
| Garcia, L | 1 |
| Mahoney, K | 1 |
| Ali, SM | 2 |
| Miller, VA | 2 |
| Stephens, PJ | 2 |
| Pira, E | 1 |
| Romano, C | 1 |
| Verga, F | 1 |
| La Vecchia, C | 1 |
| Chung, CH | 1 |
| Guthrie, VB | 1 |
| Masica, DL | 1 |
| Tokheim, C | 1 |
| Kang, H | 1 |
| Richmon, J | 1 |
| Agrawal, N | 1 |
| Fakhry, C | 1 |
| Quon, H | 1 |
| Subramaniam, RM | 1 |
| Zuo, Z | 1 |
| Seiwert, T | 1 |
| Chalmers, ZR | 1 |
| Frampton, GM | 1 |
| Karchin, R | 1 |
| Bishop, JA | 1 |
| Kerr, DA | 1 |
| Sweeney, B | 1 |
| Arpin, RN | 1 |
| Ring, M | 1 |
| Pitman, MB | 1 |
| Wilbur, DC | 1 |
| Faquin, WC | 1 |
| Rebelatto, MC | 1 |
| Midha, A | 1 |
| Mistry, A | 1 |
| Sabalos, C | 1 |
| Schechter, N | 1 |
| Li, X | 1 |
| Jin, X | 1 |
| Steele, KE | 1 |
| Robbins, PB | 1 |
| Blake-Haskins, JA | 1 |
| Walker, J | 1 |
| Mendez-Pena, JE | 1 |
| Sadow, PM | 1 |
| Nose, V | 1 |
| Hoang, MP | 1 |
| Steinau, M | 1 |
| Patel, SS | 1 |
| Unger, ER | 1 |
| Chen, CH | 1 |
| Hsu, MY | 1 |
| Jiang, RS | 1 |
| Wu, SH | 1 |
| Chen, FJ | 1 |
| Liu, SA | 1 |
| Sam, SS | 1 |
| Lebel, KA | 1 |
| Bissaillon, CL | 1 |
| Tafe, LJ | 1 |
| Tsongalis, GJ | 1 |
| Lefferts, JA | 1 |
| Shin, HJ | 1 |
| Shin, DM | 1 |
| Shah, T | 1 |
| Ro, JY | 1 |
| Nylander, K | 1 |
| Stenling, R | 1 |
| Gustafsson, H | 1 |
| Roos, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase I, Open-label Study Evaluating the Safety and Pharmacokinetics of Escalating Doses of Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Head and Neck Cancer During Surgical Procedures[NCT02415881] | Phase 1 | 64 participants (Actual) | Interventional | 2016-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for formaldehyde and Cancer of Head
| Article | Year |
|---|---|
Validation of p16 immunocytochemical staining on alcohol-fixed aspirate smears: A single-institutional study with review of the literature.
Topics: Alphapapillomavirus; Biomarkers, Tumor; Biopsy, Fine-Needle; Cyclin-Dependent Kinase Inhibitor p16; | 2022 |
1 trial available for formaldehyde and Cancer of Head
| Article | Year |
|---|---|
Development of a programmed cell death ligand-1 immunohistochemical assay validated for analysis of non-small cell lung cancer and head and neck squamous cell carcinoma.
Topics: Algorithms; Antibodies, Monoclonal; Antineoplastic Agents; Area Under Curve; B7-H1 Antigen; Biomarke | 2016 |
25 other studies available for formaldehyde and Cancer of Head
| Article | Year |
|---|---|
Mechanisms for monocyte activation in co-culture with autologous tumor spheroids.
Topics: Animals; Antibodies; Carcinoma, Squamous Cell; Coculture Techniques; Culture Media; Dactinomycin; Fo | 2002 |
The Isothermal Amplification AmpFire Assay for Human Papillomavirus (HPV) Detection and Genotyping in Formalin-Fixed, Paraffin-Embedded Oropharyngeal Cancer Samples.
Topics: Alphapapillomavirus; DNA, Viral; Formaldehyde; Genotype; Head and Neck Neoplasms; Humans; Oropharyng | 2022 |
Assessing immuno-expression of p53 protein and TP 53 gene amplification in histologically negative surgical margins of oral squamous cell carcinoma patients and normal oral mucosa.
Topics: Biomarkers, Tumor; Carcinoma, Squamous Cell; Formaldehyde; Gene Amplification; Head and Neck Neoplas | 2022 |
Deglycosylation of pathological specimens alters performance of diagnostic PDL1 antibodies.
Topics: Antibodies; B7-H1 Antigen; Formaldehyde; Head and Neck Neoplasms; Humans; Immune Checkpoint Inhibito | 2022 |
Human papillomavirus, tobacco, and poor oral hygiene can act synergetically, modulate the expression of the nuclear factor kappa B signaling pathway for the development and progression of head and neck cancer in the Pakistani population.
Topics: Alphapapillomavirus; Antibodies, Monoclonal; DNA; DNA, Viral; Formaldehyde; Head and Neck Neoplasms; | 2022 |
Effect of formalin fixation on tumour size and margins in head and neck cancer specimens.
Topics: Formaldehyde; Head and Neck Neoplasms; Humans; Margins of Excision; Neoplasm Staging; Tissue Fixatio | 2022 |
Targeted Proteomic Quantitation of NRF2 Signaling and Predictive Biomarkers in HNSCC.
Topics: Biomarkers, Tumor; Carcinoma, Squamous Cell; Cyclin-Dependent Kinase Inhibitor p16; Formaldehyde; He | 2023 |
Cytologic evaluation of p16 staining in head and neck squamous cell carcinoma in CytoLyt versus formalin-fixed material.
Topics: Aged; Biopsy, Fine-Needle; Cancer Care Facilities; Carcinoma, Squamous Cell; Cohort Studies; Cyclin- | 2019 |
Effect of Formalin Fixation for Near-Infrared Fluorescence Imaging with an Antibody-Dye Conjugate in Head and Neck Cancer Patients.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Immunological; Benzenesulfonates; ErbB Receptors; Fe | 2021 |
TXNIP, CXCL1, and AREG as key genes in formaldehyde-induced head and neck carcinoma: an in silico analysis.
Topics: Amphiregulin; Carrier Proteins; Cell Line, Tumor; Chemokine CXCL1; Computer Simulation; Formaldehyde | 2021 |
High-Throughput NanoString Analysis of Oncogenic Human Papillomavirus and Tumor Microenvironment Transcription in Head and Neck Squamous Cell Carcinoma.
Topics: Fluorometry; Formaldehyde; Gene Expression Regulation, Viral; Head and Neck Neoplasms; High-Throughp | 2021 |
Modified Alcohol-Formalin Cell Block Technique in Head and Neck Pathology Diagnosis.
Topics: Biopsy, Fine-Needle; Fixatives; Formaldehyde; Head and Neck Neoplasms; Humans; Methanol; Paraffin Em | 2018 |
Evaluation of Diagnostic Utility of a High-Risk Human Papillomavirus PCR Test on Formalin-Fixed, Paraffin-Embedded Head and Neck Tumor Tissues.
Topics: Aged; Biomarkers, Tumor; Biopsy, Fine-Needle; Cyclin-Dependent Kinase Inhibitor p16; DNA, Viral; Fea | 2018 |
ASO Author Reflections: Precise p53 Analysis in Formalin-Fixed Paraffin-Embedded Specimens Can Predict Head and Neck Squamous Cell Carcinoma Outcomes.
Topics: Exons; Formaldehyde; Head and Neck Neoplasms; Humans; Paraffin Embedding; Phenotype; Squamous Cell C | 2019 |
A gene expression profile test to resolve head & neck squamous versus lung squamous cancers.
Topics: Adult; Aged; Algorithms; Area Under Curve; Bayes Theorem; Biomarkers, Tumor; Carcinoma, Squamous Cel | 2013 |
Comprehensive genomic profiling of relapsed and metastatic adenoid cystic carcinomas by next-generation sequencing reveals potential new routes to targeted therapies.
Topics: Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Adenoid Cystic; Exons; Female; Fixatives; Forma | 2014 |
Mortality from lymphohematopoietic neoplasms and other causes in a cohort of laminated plastic workers exposed to formaldehyde.
Topics: Adult; Aged, 80 and over; Cohort Studies; Female; Formaldehyde; Head and Neck Neoplasms; Humans; Ita | 2014 |
Genomic alterations in head and neck squamous cell carcinoma determined by cancer gene-targeted sequencing.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cyclin-Dependent Kinase | 2015 |
Automated Extraction of Formalin-Fixed, Paraffin-Embedded Tissue for High-Risk Human Papillomavirus Testing of Head and Neck Squamous Cell Carcinomas Using the Roche Cobas 4800 System.
Topics: Automation, Laboratory; Carcinoma, Squamous Cell; Cyclin-Dependent Kinase Inhibitor p16; DNA, Viral; | 2016 |
RNA chromogenic in situ hybridization assay with clinical automated platform is a sensitive method in detecting high-risk human papillomavirus in squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Automation, Laboratory; Biomarkers, Tumor; Biopsy; Carcinoma, Squamo | 2017 |
Efficient DNA extraction for HPV genotyping in formalin-fixed, paraffin-embedded tissues.
Topics: Anus Neoplasms; Capsid Proteins; Carcinoma in Situ; DNA, Viral; Fixatives; Formaldehyde; Genotype; H | 2011 |
Shrinkage of head and neck cancer specimens after formalin fixation.
Topics: Adult; Aged; Female; Formaldehyde; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Stag | 2012 |
Automation of genomic DNA isolation from formalin-fixed, paraffin-embedded tissues.
Topics: Automation; DNA; DNA Mutational Analysis; Formaldehyde; Genome; Genome, Human; Glyceraldehyde-3-Phos | 2012 |
Methods in pathology. Optimization of proliferating cell nuclear antigen immunohistochemical staining by microwave heating in zinc sulfate solution.
Topics: Antibodies, Monoclonal; Antigens, Neoplasm; Autoantigens; Carcinoma, Squamous Cell; Fixatives; Forma | 1994 |
Application of dual parameter analysis in flow cytometric DNA measurements of paraffin-embedded samples.
Topics: Aneuploidy; Carcinoma, Squamous Cell; DNA, Neoplasm; Epithelium; Fixatives; Flow Cytometry; Formalde | 1994 |