formaldehyde has been researched along with Benign Neoplasms, Brain in 65 studies
paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy
| Excerpt | Relevance | Reference |
|---|---|---|
| "Temozolomide (TMZ), an alkylating agent widely used for patients with glioblastoma multiforme (GBM), has the potential to enhance the acquired immune response to GBM." | 7.77 | Pathological changes after autologous formalin-fixed tumor vaccine therapy combined with temozolomide for glioblastoma - three case reports - . ( Enomoto, T; Ishikawa, E; Matsumura, A; Morishita, Y; Nakai, K; Ohno, T; Sakamoto, N; Sato, M; Satomi, K; Takano, S; Tsuboi, K; Yamamoto, T, 2011) |
| "Using DAPI-DNA cytofluorometry, the author analyzed nuclear DNA content of formalin fixed, paraffin embedded, glioma material obtained from 14 glioma cases at surgery." | 7.68 | [DAPI-DNA cytofluorometric study of glioma cells--application of DAPI-DNA cytofluorometry to paraffin embedded archival glioma tissue for nuclear DNA content analysis]. ( Nagashima, R, 1990) |
| " Here, we report the effects of two common fixation methods, namely with formalin and methanol-acetone, on mouse brain and human glioblastoma tissue." | 3.80 | Effects of tissue fixation on coherent anti-Stokes Raman scattering images of brain. ( Galli, R; Kirsch, M; Koch, E; Schackert, G; Steiner, G; Uckermann, O, 2014) |
| "Temozolomide (TMZ), an alkylating agent widely used for patients with glioblastoma multiforme (GBM), has the potential to enhance the acquired immune response to GBM." | 3.77 | Pathological changes after autologous formalin-fixed tumor vaccine therapy combined with temozolomide for glioblastoma - three case reports - . ( Enomoto, T; Ishikawa, E; Matsumura, A; Morishita, Y; Nakai, K; Ohno, T; Sakamoto, N; Sato, M; Satomi, K; Takano, S; Tsuboi, K; Yamamoto, T, 2011) |
| "Using DAPI-DNA cytofluorometry, the author analyzed nuclear DNA content of formalin fixed, paraffin embedded, glioma material obtained from 14 glioma cases at surgery." | 3.68 | [DAPI-DNA cytofluorometric study of glioma cells--application of DAPI-DNA cytofluorometry to paraffin embedded archival glioma tissue for nuclear DNA content analysis]. ( Nagashima, R, 1990) |
| "For brain cancer and lymphohematopoietic neoplasms there were modestly elevated risks in professionals, but not industry workers." | 2.44 | Formaldehyde and cancer risk: a quantitative review of cohort studies through 2006. ( Bosetti, C; La Vecchia, C; McLaughlin, JK; Pira, E; Tarone, RE, 2008) |
| "Oligodendroglioma is a glioma subtype characterized by 1p/19q co-deletion and IDH1/IDH2 mutations, which predict a good prognosis, responsiveness to therapy, and an improved overall survival compared to other adult gliomas." | 1.72 | Utility of targeted next-generation sequencing assay to detect 1p/19q co-deletion in formalin-fixed paraffin-embedded glioma specimens. ( Adams, E; Eshleman, JR; Gocke, CD; Haley, L; Hardy, M; Huang, J; Long, P; Morsberger, L; Pallavajjala, A; Pallavajjala, R; Rodriguez, FJ; Stinnett, V; Zou, YS, 2022) |
| "Microsatellite instability was detected frequently in oral malignant melanoma." | 1.72 | Relationship of microsatellite instability to mismatch repair deficiency in malignant tumors of dogs. ( Baba, K; Hagimori, K; Horikirizono, H; Igase, M; Inanaga, S; Itamoto, K; Mizuno, T; Ohsato, Y; Sakai, Y; Sunahara, H, 2022) |
| "Intracranial germ cell tumors (IGCTs) are rare, highly curable neoplasms." | 1.72 | KRAS Mutation in Pediatric Intracranial Germ Cell Tumors. ( Amornfa, J; Chiangthong, K; Jakchairoongruang, K; Khaiman, C; Khongkhaduead, E; Lauhasurayotin, S; Nantavithya, C; Poparn, H; Santisukwongchote, S; Shotelersuk, K; Shuangshot, S; Sosothikul, D; Techavichit, P; Teerapakpinyo, C, 2022) |
| "A total of 91 patients with primary colorectal cancer were recruited." | 1.48 | A Novel and Reliable Method to Detect Microsatellite Instability in Colorectal Cancer by Next-Generation Sequencing. ( Deng, W; Fang, X; Huang, Y; Liu, C; Xu, D; Xu, J; Yuan, Y; Zhong, C; Zhu, L, 2018) |
| "Gliomas were analyzed for MGMT methylation, glioma CpG island methylator phenotype and IDH1 R132H." | 1.43 | MethylMeter(®): bisulfite-free quantitative and sensitive DNA methylation profiling and mutation detection in FFPE samples. ( Diago, OR; Hanna, MM; Hogan, DJ; McCarthy, D; Ostertag, D; Pulverer, W; Weinhaeusel, A, 2016) |
| "Diagnosis of basal-like breast cancer (BLBC) remains a bottleneck to conducting effective clinical trials for this aggressive subtype." | 1.42 | Diagnosis of Basal-Like Breast Cancer Using a FOXC1-Based Assay. ( Bagaria, SP; Bellafiore, F; Cui, X; Han, B; Jensen, TW; Li, X; Naritoku, WY; Qu, A; Ray, PS; Ray, T; Taylor, CR; Wang, J, 2015) |
| "Lung cancer is the most common cause of cancer-related deaths worldwide, and metastatic spread of the cancer rather than the primary tumor is the main cause of death." | 1.39 | Identification of accurate reference genes for RT-qPCR analysis of formalin-fixed paraffin-embedded tissue from primary non-small cell lung cancers and brain and lymph node metastases. ( Alsner, J; Hager, H; Hansen, LL; Kristensen, LS; Overgaard, J; Søes, S; Sørensen, BS, 2013) |
| "Glioblastoma is the most aggressive brain tumour of the adult with a high rate of mortality." | 1.38 | miRNAs expression analysis in paired fresh/frozen and dissected formalin fixed and paraffin embedded glioblastoma using real-time pCR. ( Baruzzi, A; Cerasoli, S; de Biase, D; Marucci, G; Morandi, L; Pession, A; Taccioli, C; Visani, M, 2012) |
| "They frequently are found in pilocytic astrocytomas, where genomic duplications involving BRAF and the poorly characterized gene KIAA1549 create fusion proteins with constitutive B-Raf kinase activity." | 1.37 | Detection of KIAA1549-BRAF fusion transcripts in formalin-fixed paraffin-embedded pediatric low-grade gliomas. ( Chan, JA; Craig, JM; Garraway, LA; Goldman, S; Kieran, MW; Ligon, AH; Ligon, KL; Lindeman, NI; Longtine, JA; Macconaill, LE; Mahmoud, M; Ozek, M; Rajaram, V; Rich, BE; Santagata, S; Sav, A; Stiles, CD; Taha, H; Tian, Y; Vena, N, 2011) |
| "Excess mortality from lymphohematopoietic malignancies, in particular myeloid leukemia, and brain cancer has been found in surveys of anatomists, pathologists, and funeral industry workers, all of whom may have worked with formaldehyde." | 1.35 | Mortality from lymphohematopoietic malignancies and brain cancer among embalmers exposed to formaldehyde. ( Beane Freeman, LE; Blair, A; Fraumeni, JF; Hauptmann, M; Hayes, RB; Herrick, RF; Hoover, RN; Hornung, RW; Lubin, JH; Stewart, PA, 2009) |
| "Primary ependymoblastomas from four children (one boy, three girls; mean age 24." | 1.33 | Cytogenetic features of ependymoblastomas. ( Hasselblatt, M; Rickert, CH, 2006) |
| "Astrocytomas contain nonrandom chromosomal abnormalities that recently have been correlated with shortened patient survival." | 1.30 | Interphase cytogenetic (in situ hybridization) analysis of astrocytomas using archival, formalin-fixed, paraffin-embedded tissue and nonfluorescent light microscopy. ( McIntire, DD; Perry, A; Tonk, V; White, CL, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (6.15) | 18.7374 |
| 1990's | 10 (15.38) | 18.2507 |
| 2000's | 16 (24.62) | 29.6817 |
| 2010's | 29 (44.62) | 24.3611 |
| 2020's | 6 (9.23) | 2.80 |
| Authors | Studies |
|---|---|
| Suzuki, A | 1 |
| Maruyama, T | 2 |
| Nitta, M | 2 |
| Komori, T | 1 |
| Ikuta, S | 1 |
| Kawamata, T | 1 |
| Muragaki, Y | 2 |
| Struckhoff, AP | 1 |
| Del Valle, L | 1 |
| Ishikawa, E | 3 |
| Tsuboi, K | 2 |
| Takano, S | 2 |
| Uchimura, E | 1 |
| Nose, T | 1 |
| Ohno, T | 3 |
| Pallavajjala, A | 1 |
| Haley, L | 1 |
| Stinnett, V | 1 |
| Adams, E | 1 |
| Pallavajjala, R | 1 |
| Huang, J | 1 |
| Morsberger, L | 1 |
| Hardy, M | 1 |
| Long, P | 1 |
| Gocke, CD | 2 |
| Eshleman, JR | 2 |
| Rodriguez, FJ | 1 |
| Zou, YS | 1 |
| Łysiak, M | 1 |
| Trybuła, M | 1 |
| Mudaisi, M | 1 |
| Bratthäll, C | 1 |
| Strandeus, M | 1 |
| Milos, P | 1 |
| Hallbeck, M | 1 |
| Malmström, A | 1 |
| Inanaga, S | 1 |
| Igase, M | 1 |
| Sakai, Y | 1 |
| Hagimori, K | 1 |
| Sunahara, H | 1 |
| Horikirizono, H | 1 |
| Itamoto, K | 1 |
| Baba, K | 1 |
| Ohsato, Y | 1 |
| Mizuno, T | 1 |
| Khaiman, C | 1 |
| Techavichit, P | 1 |
| Poparn, H | 1 |
| Chiangthong, K | 1 |
| Lauhasurayotin, S | 1 |
| Sosothikul, D | 1 |
| Shotelersuk, K | 1 |
| Nantavithya, C | 1 |
| Jakchairoongruang, K | 1 |
| Amornfa, J | 1 |
| Khongkhaduead, E | 1 |
| Santisukwongchote, S | 1 |
| Teerapakpinyo, C | 1 |
| Shuangshot, S | 1 |
| Nelson, EJ | 1 |
| Gubbiotti, MA | 1 |
| Carlin, AM | 1 |
| Nasrallah, MP | 1 |
| Van Deerlin, VM | 1 |
| Herlihy, SE | 1 |
| Gul, SI | 1 |
| Ayoub, A | 1 |
| Ali, SA | 1 |
| Hanook, S | 1 |
| Baig, DN | 1 |
| Movassaghi, M | 1 |
| Shabihkhani, M | 1 |
| Hojat, SA | 1 |
| Williams, RR | 1 |
| Chung, LK | 1 |
| Im, K | 1 |
| Lucey, GM | 1 |
| Wei, B | 1 |
| Mareninov, S | 1 |
| Wang, MW | 1 |
| Ng, DW | 1 |
| Tashjian, RS | 1 |
| Magaki, S | 1 |
| Perez-Rosendahl, M | 1 |
| Yang, I | 1 |
| Khanlou, N | 1 |
| Vinters, HV | 1 |
| Liau, LM | 1 |
| Nghiemphu, PL | 1 |
| Lai, A | 1 |
| Cloughesy, TF | 1 |
| Yong, WH | 1 |
| McElvenny, DM | 1 |
| van Tongeren, M | 1 |
| Turner, MC | 1 |
| Benke, G | 1 |
| Figuerola, J | 1 |
| Fleming, S | 1 |
| Hours, M | 1 |
| Kincl, L | 1 |
| Krewski, D | 1 |
| McLean, D | 1 |
| Parent, MÉ | 1 |
| Richardson, L | 1 |
| Schlehofer, B | 1 |
| Schlaefer, K | 1 |
| Sadetzki, S | 1 |
| Schüz, J | 1 |
| Siemiatycki, J | 1 |
| Cardis, E | 1 |
| Zhu, L | 1 |
| Huang, Y | 1 |
| Fang, X | 1 |
| Liu, C | 1 |
| Deng, W | 1 |
| Zhong, C | 1 |
| Xu, J | 1 |
| Xu, D | 1 |
| Yuan, Y | 1 |
| Haynes, HR | 1 |
| Killick-Cole, CL | 1 |
| Hares, KM | 1 |
| Redondo, J | 1 |
| Kemp, KC | 1 |
| Moutasim, KA | 1 |
| Faulkner, C | 1 |
| Wilkins, A | 1 |
| Kurian, KM | 1 |
| Sim, J | 1 |
| Nam, DH | 1 |
| Kim, Y | 1 |
| Lee, IH | 1 |
| Choi, JW | 1 |
| Sa, JK | 1 |
| Suh, YL | 1 |
| Appay, R | 1 |
| Fina, F | 1 |
| Macagno, N | 1 |
| Padovani, L | 1 |
| Colin, C | 1 |
| Barets, D | 1 |
| Ordioni, J | 1 |
| Scavarda, D | 1 |
| Giangaspero, F | 1 |
| Badiali, M | 1 |
| Korshunov, A | 1 |
| M Pfister, S | 1 |
| T W Jones, D | 1 |
| Figarella-Branger, D | 1 |
| Søes, S | 1 |
| Sørensen, BS | 1 |
| Alsner, J | 1 |
| Overgaard, J | 1 |
| Hager, H | 1 |
| Hansen, LL | 1 |
| Kristensen, LS | 1 |
| Galli, R | 1 |
| Uckermann, O | 1 |
| Koch, E | 1 |
| Schackert, G | 1 |
| Kirsch, M | 1 |
| Steiner, G | 1 |
| Toghi Eshghi, S | 1 |
| Yang, S | 1 |
| Wang, X | 2 |
| Shah, P | 1 |
| Li, X | 2 |
| Zhang, H | 1 |
| Forest, F | 1 |
| Cinotti, E | 1 |
| Yvorel, V | 1 |
| Habougit, C | 1 |
| Vassal, F | 1 |
| Nuti, C | 1 |
| Perrot, JL | 1 |
| Labeille, B | 1 |
| Péoc'h, M | 1 |
| Jensen, TW | 1 |
| Ray, T | 1 |
| Wang, J | 1 |
| Naritoku, WY | 1 |
| Han, B | 1 |
| Bellafiore, F | 1 |
| Bagaria, SP | 1 |
| Qu, A | 1 |
| Cui, X | 1 |
| Taylor, CR | 1 |
| Ray, PS | 1 |
| Saito, T | 1 |
| Iseki, H | 1 |
| Okada, Y | 1 |
| McCarthy, D | 1 |
| Pulverer, W | 1 |
| Weinhaeusel, A | 1 |
| Diago, OR | 1 |
| Hogan, DJ | 1 |
| Ostertag, D | 1 |
| Hanna, MM | 1 |
| Pescatori, L | 1 |
| Tropeano, MP | 1 |
| Manfreda, A | 1 |
| Delfini, R | 1 |
| Santoro, A | 1 |
| Liu, Z | 1 |
| Zhu, B | 1 |
| Jing, Y | 1 |
| Wang, P | 1 |
| Xu, H | 1 |
| Horbinski, C | 1 |
| Kofler, J | 1 |
| Kelly, LM | 1 |
| Murdoch, GH | 1 |
| Nikiforova, MN | 1 |
| Hauptmann, M | 1 |
| Stewart, PA | 2 |
| Lubin, JH | 1 |
| Beane Freeman, LE | 1 |
| Hornung, RW | 1 |
| Herrick, RF | 1 |
| Hoover, RN | 1 |
| Fraumeni, JF | 1 |
| Blair, A | 2 |
| Hayes, RB | 2 |
| Wiwanitkit, V | 1 |
| Cole, P | 1 |
| Adami, HO | 1 |
| Trichopoulos, D | 1 |
| Mandel, JS | 1 |
| Williams, A | 1 |
| Bartle, G | 1 |
| Sumathi, VP | 1 |
| Meis, JM | 1 |
| Mangham, DC | 1 |
| Grimer, RJ | 1 |
| Kindblom, LG | 1 |
| Sakamoto, N | 1 |
| Yamamoto, T | 1 |
| Satomi, K | 1 |
| Nakai, K | 1 |
| Sato, M | 1 |
| Enomoto, T | 1 |
| Morishita, Y | 1 |
| Matsumura, A | 1 |
| Sahm, F | 1 |
| Capper, D | 2 |
| Pusch, S | 1 |
| Balss, J | 1 |
| Koch, A | 1 |
| Langhans, CD | 1 |
| Okun, JG | 1 |
| von Deimling, A | 2 |
| Harada, S | 1 |
| Henderson, LB | 1 |
| Burger, P | 1 |
| Griffin, CA | 1 |
| Batista, DA | 1 |
| Tian, Y | 1 |
| Rich, BE | 1 |
| Vena, N | 1 |
| Craig, JM | 1 |
| Macconaill, LE | 1 |
| Rajaram, V | 1 |
| Goldman, S | 1 |
| Taha, H | 1 |
| Mahmoud, M | 1 |
| Ozek, M | 1 |
| Sav, A | 1 |
| Longtine, JA | 1 |
| Lindeman, NI | 1 |
| Garraway, LA | 1 |
| Ligon, AH | 1 |
| Stiles, CD | 1 |
| Santagata, S | 1 |
| Chan, JA | 2 |
| Kieran, MW | 1 |
| Ligon, KL | 1 |
| Gravendeel, LA | 1 |
| de Rooi, JJ | 1 |
| Eilers, PH | 1 |
| van den Bent, MJ | 1 |
| Sillevis Smitt, PA | 1 |
| French, PJ | 1 |
| Perizzolo, M | 1 |
| Winkfein, B | 1 |
| Hui, S | 1 |
| Krulicki, W | 1 |
| Demetrick, DJ | 1 |
| de Biase, D | 1 |
| Visani, M | 1 |
| Morandi, L | 1 |
| Marucci, G | 1 |
| Taccioli, C | 1 |
| Cerasoli, S | 1 |
| Baruzzi, A | 1 |
| Pession, A | 1 |
| Ferguson, AE | 1 |
| Cohn, RJ | 1 |
| Ashton, LJ | 1 |
| Truong, LN | 1 |
| Patil, S | 1 |
| Martin, SS | 1 |
| LeBlanc, JF | 1 |
| Nanda, A | 1 |
| Nordberg, ML | 1 |
| Beckner, ME | 1 |
| Lass, U | 1 |
| Hartmann, C | 1 |
| Herold-Mende, C | 1 |
| Meiboom, M | 1 |
| Mueller, W | 1 |
| Hunter, SB | 1 |
| Varma, V | 1 |
| Shehata, B | 1 |
| Nolen, JD | 1 |
| Cohen, C | 1 |
| Olson, JJ | 1 |
| Ou, CY | 1 |
| Ali, MJ | 1 |
| Navalitloha, Y | 1 |
| Vavra, MW | 1 |
| Kang, EW | 1 |
| Itskovich, AC | 1 |
| Molnar, P | 1 |
| Levy, RM | 1 |
| Groothuis, DR | 1 |
| Kotoula, V | 1 |
| Cheva, A | 1 |
| Barbanis, S | 1 |
| Papadimitriou, CS | 1 |
| Karkavelas, G | 1 |
| Temel, SG | 1 |
| Minbay, FZ | 1 |
| Kahveci, Z | 1 |
| Jennes, L | 1 |
| Kubota, T | 1 |
| Hirano, A | 1 |
| Tanaka, R | 1 |
| Takahashi, H | 1 |
| Rickert, CH | 1 |
| Hasselblatt, M | 1 |
| Kunz, F | 1 |
| Shalaby, T | 1 |
| Lang, D | 1 |
| von Büren, A | 1 |
| Hainfellner, JA | 1 |
| Slavc, I | 1 |
| Tabatabai, G | 1 |
| Grotzer, MA | 1 |
| Cankovic, M | 1 |
| Mikkelsen, T | 1 |
| Rosenblum, ML | 1 |
| Zarbo, RJ | 1 |
| Guo, T | 1 |
| Wang, W | 1 |
| Rudnick, PA | 1 |
| Song, T | 1 |
| Li, J | 1 |
| Zhuang, Z | 1 |
| Weil, RJ | 1 |
| DeVoe, DL | 1 |
| Lee, CS | 1 |
| Balgley, BM | 1 |
| Bosetti, C | 1 |
| McLaughlin, JK | 1 |
| Tarone, RE | 1 |
| Pira, E | 1 |
| La Vecchia, C | 1 |
| Haque, T | 1 |
| Faury, D | 1 |
| Albrecht, S | 1 |
| Lopez-Aguilar, E | 1 |
| Hauser, P | 1 |
| Garami, M | 1 |
| Hanzély, Z | 1 |
| Bognár, L | 1 |
| Del Maestro, RF | 1 |
| Atkinson, J | 1 |
| Nantel, A | 1 |
| Jabado, N | 1 |
| Hoyt, JW | 1 |
| Gown, AM | 1 |
| Kim, DK | 1 |
| Berger, MS | 1 |
| Wesseling, P | 1 |
| Vandersteenhoven, JJ | 1 |
| Downey, BT | 1 |
| Ruiter, DJ | 1 |
| Burger, PC | 1 |
| Yachnis, AT | 1 |
| Trojanowski, JQ | 1 |
| Krivosic, I | 1 |
| Davison, FD | 1 |
| Groves, M | 1 |
| Scaravilli, F | 1 |
| Perry, A | 1 |
| Tonk, V | 1 |
| McIntire, DD | 1 |
| White, CL | 1 |
| Cheng, Y | 1 |
| Ng, HK | 1 |
| Ding, M | 1 |
| Zhang, SF | 1 |
| Pang, JC | 1 |
| Lo, KW | 1 |
| Suzuki, SO | 1 |
| Iwaki, T | 1 |
| Almqvist, PM | 1 |
| Mah, R | 1 |
| Lendahl, U | 1 |
| Jacobsson, B | 1 |
| Hendson, G | 1 |
| Nagashima, R | 1 |
| Saracci, R | 1 |
| Shy, C | 1 |
| Hayashi, Y | 1 |
| Koike, M | 1 |
| Matsutani, M | 1 |
| Hoshino, T | 1 |
| Levine, RJ | 1 |
| Bandlow, G | 1 |
| Fischer, W | 1 |
| Thomssen, R | 1 |
| Mego, JL | 1 |
| McQueen, JD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Cross-Sectional Study of Hematotoxicity in Workers Exposed to Formaldehyde[NCT01547858] | 708 participants (Actual) | Observational | 2012-02-09 | Completed | |||
| Environmental and Genetic Determinants of NPC[NCT01257100] | 3,500 participants (Actual) | Observational | 2010-12-08 | Terminated (stopped due to Determined not to be Human Subject Research) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for formaldehyde and Benign Neoplasms, Brain
| Article | Year |
|---|---|
Formaldehyde and cancer risk: a quantitative review of cohort studies through 2006.
Topics: Air Pollutants, Occupational; Animals; Brain Neoplasms; Carcinogens, Environmental; Cohort Studies; | 2008 |
Epidemiologic evidence on the relationship between formaldehyde exposure and cancer.
Topics: Brain Neoplasms; Colorectal Neoplasms; Environmental Exposure; Formaldehyde; Humans; Leukemia; Lung | 1990 |
63 other studies available for formaldehyde and Benign Neoplasms, Brain
| Article | Year |
|---|---|
Modified rapid immunohistochemical staining for intraoperative diagnosis of malignant brain tumors.
Topics: Adult; Antigens, CD20; Biomarkers, Tumor; Brain Neoplasms; CD3 Complex; Female; Fixatives; Formaldeh | 2017 |
Neurospheres and glial cell cultures: immunocytochemistry for cell phenotyping.
Topics: Animals; Astrocytes; Biomarkers; Brain Neoplasms; Cell Culture Techniques; Cell Differentiation; Cel | 2013 |
Intratumoral injection of IL-2-activated NK cells enhances the antitumor effect of intradermally injected paraformaldehyde-fixed tumor vaccine in a rat intracranial brain tumor model.
Topics: Animals; Brain Neoplasms; Cancer Vaccines; Cytotoxicity Tests, Immunologic; Disease Models, Animal; | 2004 |
Utility of targeted next-generation sequencing assay to detect 1p/19q co-deletion in formalin-fixed paraffin-embedded glioma specimens.
Topics: Brain Neoplasms; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 1; Chromosome | 2022 |
The sex-dependent role of the androgen receptor in glioblastoma: results of molecular analyses.
Topics: Brain Neoplasms; DNA Methylation; Female; Formaldehyde; Glioblastoma; Humans; Isocitrate Dehydrogena | 2022 |
Relationship of microsatellite instability to mismatch repair deficiency in malignant tumors of dogs.
Topics: Animals; Brain Neoplasms; Colorectal Neoplasms; DNA; DNA Mismatch Repair; Dog Diseases; Dogs; Formal | 2022 |
KRAS Mutation in Pediatric Intracranial Germ Cell Tumors.
Topics: Adolescent; Brain Neoplasms; Child; Child, Preschool; Female; Formaldehyde; Germinoma; Humans; Male; | 2022 |
Clinical Evaluation of IDH Mutation Status in Formalin-Fixed Paraffin-Embedded Tissue in Gliomas.
Topics: Brain Neoplasms; Formaldehyde; Glioma; Humans; Isocitrate Dehydrogenase; Mutation; Paraffin Embeddin | 2023 |
Profilin 3 genetic architecture in glioma formalin fixed paraffin embedded (FFPE) archive.
Topics: Brain Neoplasms; Formaldehyde; Gene Expression Regulation, Neoplastic; Glioma; Humans; Paraffin Embe | 2021 |
Early experience with formalin-fixed paraffin-embedded (FFPE) based commercial clinical genomic profiling of gliomas-robust and informative with caveats.
Topics: Adolescent; Adult; Aged; Brain Neoplasms; Class I Phosphatidylinositol 3-Kinases; ErbB Receptors; Fe | 2017 |
The INTEROCC case-control study: risk of meningioma and occupational exposure to selected combustion products, dusts and other chemical agents.
Topics: Adult; Aged; Asbestos; Brain Neoplasms; Case-Control Studies; Dust; Female; Formaldehyde; Humans; Lo | 2018 |
A Novel and Reliable Method to Detect Microsatellite Instability in Colorectal Cancer by Next-Generation Sequencing.
Topics: Brain Neoplasms; Colorectal Neoplasms; Data Accuracy; DNA Mismatch Repair; DNA Repair Enzymes; Forma | 2018 |
Evaluation of the quality of RNA extracted from archival FFPE glioblastoma and epilepsy surgical samples for gene expression assays.
Topics: Brain Neoplasms; Case-Control Studies; Epilepsy, Temporal Lobe; Fixatives; Formaldehyde; Gene Expres | 2018 |
Comparison of 1p and 19q status of glioblastoma by whole exome sequencing, array-comparative genomic hybridization, and fluorescence in situ hybridization.
Topics: Adult; Brain Neoplasms; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 19; Comparative Genomic | 2018 |
Duplications of KIAA1549 and BRAF screening by Droplet Digital PCR from formalin-fixed paraffin-embedded DNA is an accurate alternative for KIAA1549-BRAF fusion detection in pilocytic astrocytomas.
Topics: Astrocytoma; Brain Neoplasms; DNA, Neoplasm; Formaldehyde; Humans; Oncogene Proteins, Fusion; Paraff | 2018 |
Identification of accurate reference genes for RT-qPCR analysis of formalin-fixed paraffin-embedded tissue from primary non-small cell lung cancers and brain and lymph node metastases.
Topics: beta Karyopherins; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Formaldehyde; Gene Expression; G | 2013 |
Effects of tissue fixation on coherent anti-Stokes Raman scattering images of brain.
Topics: Acetone; Animals; Brain; Brain Neoplasms; Central Nervous System; Female; Formaldehyde; Glioblastoma | 2014 |
Imaging of N-linked glycans from formalin-fixed paraffin-embedded tissue sections using MALDI mass spectrometry.
Topics: Animals; Brain; Brain Neoplasms; Carbohydrate Conformation; Formaldehyde; Glioblastoma; Glycosylatio | 2014 |
Ex vivo confocal microscopy imaging to identify tumor tissue on freshly removed brain sample.
Topics: Brain; Brain Neoplasms; Carcinoma; Cryopreservation; Formaldehyde; Glioma; Humans; Meningioma; Micro | 2015 |
Diagnosis of Basal-Like Breast Cancer Using a FOXC1-Based Assay.
Topics: Adult; Aged; Area Under Curve; Biomarkers, Tumor; Brain Neoplasms; Breast Neoplasms; Carcinoma, Basa | 2015 |
[II. Autologous formalin-fixed tumor vaccine for newly diagnosed glioblastoma].
Topics: Antigens, Neoplasm; Autoantigens; Brain Neoplasms; Cancer Vaccines; Clinical Trials as Topic; Formal | 2015 |
MethylMeter(®): bisulfite-free quantitative and sensitive DNA methylation profiling and mutation detection in FFPE samples.
Topics: Brain Neoplasms; CpG Islands; DNA Copy Number Variations; DNA Methylation; DNA Modification Methylas | 2016 |
Three-Dimensional Anatomy of the White Matter Fibers of the Temporal Lobe: Surgical Implications.
Topics: Adult; Aged; Brain Neoplasms; Cerebral Angiography; Cryopreservation; Dissection; Female; Fixatives; | 2017 |
Reduced antigenicity of formaldehyde-fixed arterial allografts and their potential clinical application.
Topics: Animals; Arteries; Brain Neoplasms; Cadaver; Fixatives; Formaldehyde; Histocompatibility Antigens Cl | 2008 |
Diagnostic use of IDH1/2 mutation analysis in routine clinical testing of formalin-fixed, paraffin-embedded glioma tissues.
Topics: Biomarkers, Tumor; Brain Neoplasms; DNA Mutational Analysis; Formaldehyde; Glioma; Humans; Isocitrat | 2009 |
Mortality from lymphohematopoietic malignancies and brain cancer among embalmers exposed to formaldehyde.
Topics: Aged; Aged, 80 and over; Brain Neoplasms; Female; Fixatives; Formaldehyde; Funeral Rites; Hematologi | 2009 |
Correspondence regarding: diagnostic utility of IDH1/2 mutation analysis in routine clinical testing of formalin-fixed paraffin-embedded glioma tissues. J Neuropathol Exp Neurol 2009:68;1319-25.
Topics: Biomarkers, Tumor; Brain Neoplasms; Cost-Benefit Analysis; Diagnosis, Differential; DNA Mutational A | 2010 |
Re: Mortality from lymphohematopoietic malignancies and brain cancer among embalmers exposed to formaldehyde.
Topics: Adult; Aged; Brain Neoplasms; Case-Control Studies; Fixatives; Formaldehyde; Hematologic Neoplasms; | 2010 |
Detection of ASPL/TFE3 fusion transcripts and the TFE3 antigen in formalin-fixed, paraffin-embedded tissue in a series of 18 cases of alveolar soft part sarcoma: useful diagnostic tools in cases with unusual histological features.
Topics: Adolescent; Adult; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Brain Neoplasms; Chi | 2011 |
Pathological changes after autologous formalin-fixed tumor vaccine therapy combined with temozolomide for glioblastoma - three case reports - .
Topics: Adjuvants, Immunologic; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cancer Vacc | 2011 |
Detection of 2-hydroxyglutarate in formalin-fixed paraffin-embedded glioma specimens by gas chromatography/mass spectrometry.
Topics: Brain Neoplasms; Fixatives; Formaldehyde; Gas Chromatography-Mass Spectrometry; Glioma; Glutarates; | 2012 |
Genomic changes in gliomas detected using single nucleotide polymorphism array in formalin-fixed, paraffin-embedded tissue: superior results compared with microsatellite analysis.
Topics: Adult; Brain Neoplasms; Chromosomes, Human; DNA, Neoplasm; Female; Formaldehyde; Genome, Human; Glio | 2011 |
Detection of KIAA1549-BRAF fusion transcripts in formalin-fixed paraffin-embedded pediatric low-grade gliomas.
Topics: Adolescent; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Child; Child, Preschool; Comparative Ge | 2011 |
Gene expression profiles of gliomas in formalin-fixed paraffin-embedded material.
Topics: Brain Neoplasms; Cluster Analysis; Fixatives; Formaldehyde; Frozen Sections; Gene Expression Profili | 2012 |
IDH mutation detection in formalin-fixed paraffin-embedded gliomas using multiplex PCR and single-base extension.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Female; Formaldehyde; Glioma; Humans; I | 2012 |
miRNAs expression analysis in paired fresh/frozen and dissected formalin fixed and paraffin embedded glioblastoma using real-time pCR.
Topics: Adult; Aged; Brain Neoplasms; Female; Fixatives; Formaldehyde; Gene Expression Profiling; Gene Expre | 2012 |
Use of formalin-fixed paraffin-embedded tumor tissue as a DNA source in molecular epidemiological studies of pediatric CNS tumors.
Topics: Astrocytoma; Brain Neoplasms; Cerebellar Neoplasms; Child; DNA; DNA Fragmentation; DNA Mutational An | 2012 |
Rapid detection of high-level oncogene amplifications in ultrasonic surgical aspirations of brain tumors.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Biopsy, Needle; Brain Neoplasms; Centrifugation; | 2012 |
Chromogenic in situ hybridization is a reliable alternative to fluorescence in situ hybridization for diagnostic testing of 1p and 19q loss in paraffin-embedded gliomas.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Chromosome Deletion; Chromosomes, Human | 2013 |
Apolipoprotein D expression in primary brain tumors: analysis by quantitative RT-PCR in formalin-fixed, paraffin-embedded tissue.
Topics: Apolipoproteins; Apolipoproteins D; Brain Neoplasms; Cell Proliferation; Fixatives; Formaldehyde; Gl | 2005 |
Isolation of drug delivery from drug effect: problems of optimizing drug delivery parameters.
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Drug Adminis | 2006 |
hTERT immunopositivity patterns in the normal brain and in astrocytic tumors.
Topics: Adult; Aged; Astrocytes; Astrocytoma; Brain Chemistry; Brain Neoplasms; Child; Endothelial Cells; Fe | 2006 |
Microwave-assisted antigen retrieval and incubation with cox-2 antibody of archival paraffin-embedded human oligodendroglioma and astrocytomas.
Topics: Antigens, Neoplasm; Astrocytoma; Brain Neoplasms; Calibration; Cyclooxygenase 2; Fixatives; Formalde | 2006 |
Fine structural study of a cerebral tumor characterized by a honeycomb appearance after a 20-year post-mortem interval.
Topics: Adult; Autopsy; Brain Neoplasms; Diagnostic Errors; Ependymoma; Formaldehyde; Humans; Immunohistoche | 2006 |
Cytogenetic features of ependymoblastomas.
Topics: Brain Neoplasms; Child, Preschool; DNA; Female; Fixatives; Formaldehyde; Gene Dosage; Glial Fibrilla | 2006 |
Quantitative mRNA expression analysis of neurotrophin-receptor TrkC and oncogene c-MYC from formalin-fixed, paraffin-embedded primitive neuroectodermal tumor samples.
Topics: Adolescent; Adult; Brain Neoplasms; Child; Child, Preschool; Formaldehyde; Gene Expression; Gene Exp | 2006 |
A simplified laboratory validated assay for MGMT promoter hypermethylation analysis of glioma specimens from formalin-fixed paraffin-embedded tissue.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Astrocytoma; Brain Neoplasms; DNA Modification Methylase | 2007 |
Proteome analysis of microdissected formalin-fixed and paraffin-embedded tissue specimens.
Topics: Amino Acid Sequence; Brain Neoplasms; Chromatography, Liquid; False Positive Reactions; Fixatives; F | 2007 |
Gene expression profiling from formalin-fixed paraffin-embedded tumors of pediatric glioblastoma.
Topics: Adolescent; Brain Neoplasms; Child; Child, Preschool; Female; Formaldehyde; Gene Expression Profilin | 2007 |
Analysis of proliferative grade in glial neoplasms using antibodies to the Ki-67 defined antigen and PCNA in formalin fixed, deparaffinized tissues.
Topics: Antibodies, Monoclonal; Biomarkers, Tumor; Brain Neoplasms; Cell Cycle; Cell Division; Fixatives; Fl | 1995 |
Cellular components of microvascular proliferation in human glial and metastatic brain neoplasms. A light microscopic and immunohistochemical study of formalin-fixed, routinely processed material.
Topics: Actins; Brain Neoplasms; Capillaries; Cell Division; Formaldehyde; Granulation Tissue; Humans; Immun | 1993 |
Studies of childhood brain tumors using immunohistochemistry and microwave technology: methodological considerations.
Topics: Adult; Antibodies, Monoclonal; Brain Neoplasms; Cerebellar Neoplasms; Child, Preschool; Formaldehyde | 1994 |
[Specimen fixation in seminoma].
Topics: Brain Neoplasms; Dysgerminoma; Fixatives; Formaldehyde; Humans; Hydrogen-Ion Concentration; Osmolar | 1993 |
The effects of formalin fixation on the detection of apoptosis in human brain by in situ end-labelling of DNA.
Topics: Acquired Immunodeficiency Syndrome; Animals; Apoptosis; Brain; Brain Neoplasms; Digoxigenin; DNA; Fo | 1995 |
Interphase cytogenetic (in situ hybridization) analysis of astrocytomas using archival, formalin-fixed, paraffin-embedded tissue and nonfluorescent light microscopy.
Topics: Adult; Aged; Astrocytoma; Brain Neoplasms; Chromosome Aberrations; Chromosomes, Human, Pair 10; Chro | 1997 |
Molecular analysis of microdissected de novo glioblastomas and paired astrocytic tumors.
Topics: Adult; Aged; Alleles; Antibodies, Monoclonal; Astrocytes; Brain Neoplasms; Chromosome Mapping; Disse | 1999 |
Non-isotopic in situ hybridization of CD44 transcript in formalin-fixed paraffin-embedded sections.
Topics: Brain Neoplasms; Digoxigenin; Fixatives; Formaldehyde; Humans; Hyaluronan Receptors; Immunohistochem | 1999 |
Immunohistochemical detection of nestin in pediatric brain tumors.
Topics: Adolescent; Astrocytoma; Brain Neoplasms; Child; Child, Preschool; Ependymoma; Female; Fixatives; Fo | 2002 |
[DAPI-DNA cytofluorometric study of glioma cells--application of DAPI-DNA cytofluorometry to paraffin embedded archival glioma tissue for nuclear DNA content analysis].
Topics: Adult; Aged; Brain Neoplasms; Cell Nucleus; Child, Preschool; Cytophotometry; DNA, Neoplasm; Female; | 1990 |
Effects of fixation time and enzymatic digestion on immunohistochemical demonstration of bromodeoxyuridine in formalin-fixed, paraffin-embedded tissue.
Topics: Animals; Brain Neoplasms; Bromodeoxyuridine; Digestive System; Formaldehyde; Humans; Immunohistochem | 1988 |
Formaldehyde, cancer, and social class.
Topics: Adult; Aged; Brain Neoplasms; Formaldehyde; Humans; Leukemia; Male; Middle Aged; Socioeconomic Facto | 1985 |
[Mechanism of the immunological adjuvant effect of vaccinia-virus].
Topics: Adjuvants, Immunologic; Aluminum Hydroxide; Animals; Antibody Formation; Antigens, Viral; Brain Neop | 1972 |
Formaldehyde-treated 131-I-albumin: a possible brain-tumor scanning agent.
Topics: Animals; Brain Neoplasms; Ependymoma; Formaldehyde; Hydrogen-Ion Concentration; Injections, Intraven | 1968 |