formaldehyde has been researched along with Asymmetric Diabetic Proximal Motor Neuropathy in 14 studies
paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy
| Excerpt | Relevance | Reference |
|---|---|---|
| "We evaluated the effects of zonisamide on inflammatory and neuropathic pain using the mouse formalin test and streptozotocin (STZ)-induced diabetic mice with a reduced withdrawal threshold to mechanical stimuli, respectively." | 7.74 | Zonisamide suppresses pain symptoms of formalin-induced inflammatory and streptozotocin-induced diabetic neuropathy. ( Murakami, T; Ono, H; Tanabe, M, 2008) |
| "An excess of excitatory pathway activation via N-methyl-D-aspartate (NMDA) receptors has been described in neuropathic pain that responds poorly to morphine." | 7.71 | Magnesium increases morphine analgesic effect in different experimental models of pain. ( Begon, S; Dubray, C; Eschalier, A; Pickering, G, 2002) |
| " Chronic administration of minocycline (40 and 80 mg/kg, i." | 5.37 | Minocycline attenuates the development of diabetic neuropathic pain: possible anti-inflammatory and anti-oxidant mechanisms. ( Dua, K; Kulkarni, SK; Pabreja, K; Padi, SS; Sharma, S, 2011) |
| "Rats developed tactile allodynia within days of the onset of diabetes and which persisted for up to 8 weeks." | 5.29 | Tactile allodynia and formalin hyperalgesia in streptozotocin-diabetic rats: effects of insulin, aldose reductase inhibition and lidocaine. ( Calcutt, NA; Chaplan, SR; Jorge, MC; Yaksh, TL, 1996) |
| "We evaluated the effects of zonisamide on inflammatory and neuropathic pain using the mouse formalin test and streptozotocin (STZ)-induced diabetic mice with a reduced withdrawal threshold to mechanical stimuli, respectively." | 3.74 | Zonisamide suppresses pain symptoms of formalin-induced inflammatory and streptozotocin-induced diabetic neuropathy. ( Murakami, T; Ono, H; Tanabe, M, 2008) |
| "An excess of excitatory pathway activation via N-methyl-D-aspartate (NMDA) receptors has been described in neuropathic pain that responds poorly to morphine." | 3.71 | Magnesium increases morphine analgesic effect in different experimental models of pain. ( Begon, S; Dubray, C; Eschalier, A; Pickering, G, 2002) |
| "Ifenprodil was administered in PDN rats while saline was administered intrathecally in the control group." | 1.62 | Ifenprodil Reduced Expression of Activated Microglia, BDNF and DREAM Proteins in the Spinal Cord Following Formalin Injection During the Early Stage of Painful Diabetic Neuropathy in Rats. ( Ab Aziz, CB; Ismail, CAN; Long, I; Suppian, R, 2021) |
| "The complications of diabetic polyneuropathy (DN) determines its level of severity." | 1.56 | Expressions of spinal microglia activation, BDNF, and DREAM proteins correlated with formalin-induced nociceptive responses in painful and painless diabetic neuropathy rats. ( Ab Aziz, CB; Ismail, CAN; Long, I; Suppian, R, 2020) |
| " Chronic administration of minocycline (40 and 80 mg/kg, i." | 1.37 | Minocycline attenuates the development of diabetic neuropathic pain: possible anti-inflammatory and anti-oxidant mechanisms. ( Dua, K; Kulkarni, SK; Pabreja, K; Padi, SS; Sharma, S, 2011) |
| "Rats developed tactile allodynia within days of the onset of diabetes and which persisted for up to 8 weeks." | 1.29 | Tactile allodynia and formalin hyperalgesia in streptozotocin-diabetic rats: effects of insulin, aldose reductase inhibition and lidocaine. ( Calcutt, NA; Chaplan, SR; Jorge, MC; Yaksh, TL, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 3 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Ismail, CAN | 3 |
| Ghazali, AK | 1 |
| Suppian, R | 3 |
| Abd Aziz, CB | 1 |
| Long, I | 3 |
| Ab Aziz, CB | 2 |
| Sałat, K | 1 |
| Kołaczkowski, M | 1 |
| Furgała, A | 1 |
| Rojek, A | 1 |
| Śniecikowska, J | 1 |
| Varney, MA | 1 |
| Newman-Tancredi, A | 1 |
| Silva, M | 1 |
| Martins, D | 1 |
| Charrua, A | 1 |
| Piscitelli, F | 1 |
| Tavares, I | 1 |
| Morgado, C | 1 |
| Di Marzo, V | 1 |
| Huang, YH | 1 |
| Hou, SY | 1 |
| Cheng, JK | 1 |
| Wu, CH | 1 |
| Lin, CR | 1 |
| Tanabe, M | 1 |
| Murakami, T | 1 |
| Ono, H | 1 |
| Jolivalt, CG | 1 |
| Mizisin, LM | 1 |
| Nelson, A | 1 |
| Cunha, JM | 2 |
| Ramos, KM | 1 |
| Bonke, D | 1 |
| Calcutt, NA | 2 |
| Pabreja, K | 1 |
| Dua, K | 1 |
| Sharma, S | 1 |
| Padi, SS | 1 |
| Kulkarni, SK | 1 |
| Schreiber, AK | 1 |
| Neufeld, M | 1 |
| Jesus, CH | 1 |
| Christianson, JA | 1 |
| Ryals, JM | 1 |
| McCarson, KE | 1 |
| Wright, DE | 1 |
| Jorge, MC | 1 |
| Yaksh, TL | 1 |
| Chaplan, SR | 1 |
| Kamei, J | 1 |
| Taki, K | 1 |
| Ohsawa, M | 1 |
| Hitosugi, H | 1 |
| Begon, S | 1 |
| Pickering, G | 1 |
| Eschalier, A | 1 |
| Dubray, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Magnesium Oral Supplementation to Reduce Pain in Patients With Severe Peripheral Arterial Occlusive Disease: The MAG-PAPER Randomized Clinical Trial[NCT02455726] | 150 participants (Anticipated) | Interventional | 2015-09-30 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
14 other studies available for formaldehyde and Asymmetric Diabetic Proximal Motor Neuropathy
| Article | Year |
|---|---|
Lower Formalin-Induced Pain Responses in Painless Diabetic Neuropathy Rat Correlate with the Reduced Spinal Cord NR2B Subunit of N-Methyl-D-Aspartate Receptor Activation.
Topics: Animals; Diabetes Mellitus; Diabetic Neuropathies; Formaldehyde; Male; Pain; Rats; Rats, Sprague-Daw | 2022 |
Expressions of spinal microglia activation, BDNF, and DREAM proteins correlated with formalin-induced nociceptive responses in painful and painless diabetic neuropathy rats.
Topics: Animals; Brain-Derived Neurotrophic Factor; Diabetes Mellitus; Diabetic Neuropathies; Formaldehyde; | 2020 |
Ifenprodil Reduced Expression of Activated Microglia, BDNF and DREAM Proteins in the Spinal Cord Following Formalin Injection During the Early Stage of Painful Diabetic Neuropathy in Rats.
Topics: Animals; Brain-Derived Neurotrophic Factor; Diabetic Neuropathies; Formaldehyde; Kv Channel-Interact | 2021 |
Antinociceptive, antiallodynic and antihyperalgesic effects of the 5-HT
Topics: Analgesics; Animals; Antineoplastic Agents; Cyclohexanes; Diabetic Neuropathies; Disease Models, Ani | 2017 |
Endovanilloid control of pain modulation by the rostroventromedial medulla in an animal model of diabetic neuropathy.
Topics: Amides; Amidohydrolases; Analgesics, Non-Narcotic; Animals; Arachidonic Acids; Capsaicin; Chronic Pa | 2016 |
Pulsed radiofrequency attenuates diabetic neuropathic pain and suppresses formalin-evoked spinal glutamate release in rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Formaldehyde; Glutamic Acid; Male; | 2016 |
Zonisamide suppresses pain symptoms of formalin-induced inflammatory and streptozotocin-induced diabetic neuropathy.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Formaldehyde; Inflammation; Isoxazo | 2008 |
B vitamins alleviate indices of neuropathic pain in diabetic rats.
Topics: Aldehydes; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dose-Resp | 2009 |
Minocycline attenuates the development of diabetic neuropathic pain: possible anti-inflammatory and anti-oxidant mechanisms.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Behavior, Animal; Biomarkers; Blood Glucose; Body W | 2011 |
Peripheral antinociceptive effect of anandamide and drugs that affect the endocannabinoid system on the formalin test in normal and streptozotocin-diabetic rats.
Topics: Analgesics; Animals; Arachidonic Acids; Behavior, Animal; Capsaicin; Diabetes Mellitus, Experimental | 2012 |
Beneficial actions of neurotrophin treatment on diabetes-induced hypoalgesia in mice.
Topics: Animals; Behavior, Animal; Blood Glucose; Body Weight; Cold Temperature; Diabetes Mellitus, Experime | 2003 |
Tactile allodynia and formalin hyperalgesia in streptozotocin-diabetic rats: effects of insulin, aldose reductase inhibition and lidocaine.
Topics: Aldehyde Reductase; Anesthetics, Local; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dia | 1996 |
Modulation of the formalin-induced nociceptive response by diabetes: possible involvement of intracellular calcium.
Topics: Animals; Calcium; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disinfectants; Enzyme Inhi | 2000 |
Magnesium increases morphine analgesic effect in different experimental models of pain.
Topics: Analgesics, Opioid; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Drug Synergism; | 2002 |