formaldehyde has been researched along with Astrocytoma in 11 studies
paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy
Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)
| Excerpt | Relevance | Reference |
|---|---|---|
| "They frequently are found in pilocytic astrocytomas, where genomic duplications involving BRAF and the poorly characterized gene KIAA1549 create fusion proteins with constitutive B-Raf kinase activity." | 1.37 | Detection of KIAA1549-BRAF fusion transcripts in formalin-fixed paraffin-embedded pediatric low-grade gliomas. ( Chan, JA; Craig, JM; Garraway, LA; Goldman, S; Kieran, MW; Ligon, AH; Ligon, KL; Lindeman, NI; Longtine, JA; Macconaill, LE; Mahmoud, M; Ozek, M; Rajaram, V; Rich, BE; Santagata, S; Sav, A; Stiles, CD; Taha, H; Tian, Y; Vena, N, 2011) |
| "Astrocytomas contain nonrandom chromosomal abnormalities that recently have been correlated with shortened patient survival." | 1.30 | Interphase cytogenetic (in situ hybridization) analysis of astrocytomas using archival, formalin-fixed, paraffin-embedded tissue and nonfluorescent light microscopy. ( McIntire, DD; Perry, A; Tonk, V; White, CL, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Appay, R | 1 |
| Fina, F | 1 |
| Macagno, N | 1 |
| Padovani, L | 1 |
| Colin, C | 1 |
| Barets, D | 1 |
| Ordioni, J | 1 |
| Scavarda, D | 1 |
| Giangaspero, F | 1 |
| Badiali, M | 1 |
| Korshunov, A | 1 |
| M Pfister, S | 1 |
| T W Jones, D | 1 |
| Figarella-Branger, D | 1 |
| Tian, Y | 1 |
| Rich, BE | 1 |
| Vena, N | 1 |
| Craig, JM | 1 |
| Macconaill, LE | 1 |
| Rajaram, V | 1 |
| Goldman, S | 1 |
| Taha, H | 1 |
| Mahmoud, M | 1 |
| Ozek, M | 1 |
| Sav, A | 1 |
| Longtine, JA | 1 |
| Lindeman, NI | 1 |
| Garraway, LA | 1 |
| Ligon, AH | 1 |
| Stiles, CD | 1 |
| Santagata, S | 1 |
| Chan, JA | 1 |
| Kieran, MW | 1 |
| Ligon, KL | 1 |
| Ferguson, AE | 1 |
| Cohn, RJ | 1 |
| Ashton, LJ | 1 |
| Kotoula, V | 1 |
| Cheva, A | 1 |
| Barbanis, S | 1 |
| Papadimitriou, CS | 1 |
| Karkavelas, G | 1 |
| Temel, SG | 1 |
| Minbay, FZ | 1 |
| Kahveci, Z | 1 |
| Jennes, L | 1 |
| Johnson, NA | 1 |
| Hamoudi, RA | 1 |
| Ichimura, K | 1 |
| Liu, L | 1 |
| Pearson, DM | 1 |
| Collins, VP | 1 |
| Du, MQ | 1 |
| Cankovic, M | 1 |
| Mikkelsen, T | 1 |
| Rosenblum, ML | 1 |
| Zarbo, RJ | 1 |
| Perry, A | 1 |
| Tonk, V | 1 |
| McIntire, DD | 1 |
| White, CL | 1 |
| McLendon, RE | 1 |
| Cleveland, L | 1 |
| Pegram, C | 1 |
| Bigner, SH | 1 |
| Bigner, DD | 1 |
| Friedman, HS | 1 |
| Almqvist, PM | 1 |
| Mah, R | 1 |
| Lendahl, U | 1 |
| Jacobsson, B | 1 |
| Hendson, G | 1 |
| Narotzky, R | 1 |
| Bondareff, W | 1 |
11 other studies available for formaldehyde and Astrocytoma
| Article | Year |
|---|---|
Duplications of KIAA1549 and BRAF screening by Droplet Digital PCR from formalin-fixed paraffin-embedded DNA is an accurate alternative for KIAA1549-BRAF fusion detection in pilocytic astrocytomas.
Topics: Astrocytoma; Brain Neoplasms; DNA, Neoplasm; Formaldehyde; Humans; Oncogene Proteins, Fusion; Paraff | 2018 |
Detection of KIAA1549-BRAF fusion transcripts in formalin-fixed paraffin-embedded pediatric low-grade gliomas.
Topics: Adolescent; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Child; Child, Preschool; Comparative Ge | 2011 |
Use of formalin-fixed paraffin-embedded tumor tissue as a DNA source in molecular epidemiological studies of pediatric CNS tumors.
Topics: Astrocytoma; Brain Neoplasms; Cerebellar Neoplasms; Child; DNA; DNA Fragmentation; DNA Mutational An | 2012 |
hTERT immunopositivity patterns in the normal brain and in astrocytic tumors.
Topics: Adult; Aged; Astrocytes; Astrocytoma; Brain Chemistry; Brain Neoplasms; Child; Endothelial Cells; Fe | 2006 |
Microwave-assisted antigen retrieval and incubation with cox-2 antibody of archival paraffin-embedded human oligodendroglioma and astrocytomas.
Topics: Antigens, Neoplasm; Astrocytoma; Brain Neoplasms; Calibration; Cyclooxygenase 2; Fixatives; Formalde | 2006 |
Application of array CGH on archival formalin-fixed paraffin-embedded tissues including small numbers of microdissected cells.
Topics: Astrocytoma; Biological Specimen Banks; Biomarkers, Tumor; DNA, Neoplasm; Formaldehyde; Humans; Micr | 2006 |
A simplified laboratory validated assay for MGMT promoter hypermethylation analysis of glioma specimens from formalin-fixed paraffin-embedded tissue.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Astrocytoma; Brain Neoplasms; DNA Modification Methylase | 2007 |
Interphase cytogenetic (in situ hybridization) analysis of astrocytomas using archival, formalin-fixed, paraffin-embedded tissue and nonfluorescent light microscopy.
Topics: Adult; Aged; Astrocytoma; Brain Neoplasms; Chromosome Aberrations; Chromosomes, Human, Pair 10; Chro | 1997 |
Immunohistochemical detection of the DNA repair enzyme O6-methylguanine-DNA methyltransferase in formalin-fixed, paraffin-embedded astrocytomas.
Topics: Adult; Antibodies, Monoclonal; Astrocytoma; DNA Repair; Fixatives; Formaldehyde; Humans; Immunohisto | 1998 |
Immunohistochemical detection of nestin in pediatric brain tumors.
Topics: Adolescent; Astrocytoma; Brain Neoplasms; Child; Child, Preschool; Ependymoma; Female; Fixatives; Fo | 2002 |
Biogenic amines in cultured neuroblastoma and astrocytoma cells.
Topics: Animals; Astrocytoma; Biogenic Amines; Carbon Radioisotopes; Cell Line; Cells, Cultured; Clone Cells | 1974 |