formaldehyde has been researched along with Anxiety in 19 studies
paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The GABA amides of the antidepressants nortriptyline and fluoxetine, 1 and 2, were compared to their respective parent compounds in rodent models of pain." | 7.75 | Gamma-aminobutyric acid amides of nortriptyline and fluoxetine display improved pain suppressing activity. ( Aharoni, A; Geffen, Y; Gil-Ad, I; Halbfinger, E; Nisemblat, Y; Nudelman, A; Rephaeli, A; Tarasenko, I; Tarasenko, N; Weizman, A, 2009) |
| "Pain associated-anxiety induced by formalin, which resulted in a significant delay in the development of tolerance to morphine antinociception, failed to prevent the development of physical dependence as evidenced by naloxone challenge." | 7.69 | Morphine dependence with or without tolerance in formalin-treated mice: further evidence for the dissociation. ( Kaneto, H; Rahman, AF; Takahashi, M, 1994) |
| "The mechanism underlying the previous findings that the development of antinociceptive tolerance to morphine was significantly delayed in the presence of inflammatory pain induced by formalin was examined." | 7.69 | Involvement of pain associated anxiety in the development of morphine tolerance in formalin treated mice. ( Kaneto, H; Rahman, AF; Takahashi, M, 1994) |
| "Formalin-induced acute inflammatory pain was established by intraplantar injection of 1% formalin without anesthesia or with anesthesia using the clinical anesthetics sevoflurane, propofol, or pentobarbital sodium." | 3.81 | Differential effects of general anesthetics on anxiety-like behavior in formalin-induced pain: involvement of ERK activation in the anterior cingulate cortex. ( Dai, RP; Li, CQ; Luo, C; Luo, W; Xu, JM; Zhang, YL; Zhou, FH, 2015) |
| "The GABA amides of the antidepressants nortriptyline and fluoxetine, 1 and 2, were compared to their respective parent compounds in rodent models of pain." | 3.75 | Gamma-aminobutyric acid amides of nortriptyline and fluoxetine display improved pain suppressing activity. ( Aharoni, A; Geffen, Y; Gil-Ad, I; Halbfinger, E; Nisemblat, Y; Nudelman, A; Rephaeli, A; Tarasenko, I; Tarasenko, N; Weizman, A, 2009) |
| "Pain associated-anxiety induced by formalin, which resulted in a significant delay in the development of tolerance to morphine antinociception, failed to prevent the development of physical dependence as evidenced by naloxone challenge." | 3.69 | Morphine dependence with or without tolerance in formalin-treated mice: further evidence for the dissociation. ( Kaneto, H; Rahman, AF; Takahashi, M, 1994) |
| "The mechanism underlying the previous findings that the development of antinociceptive tolerance to morphine was significantly delayed in the presence of inflammatory pain induced by formalin was examined." | 3.69 | Involvement of pain associated anxiety in the development of morphine tolerance in formalin treated mice. ( Kaneto, H; Rahman, AF; Takahashi, M, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.53) | 18.7374 |
| 1990's | 4 (21.05) | 18.2507 |
| 2000's | 6 (31.58) | 29.6817 |
| 2010's | 7 (36.84) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sugiyama, A | 1 |
| Nagase, H | 1 |
| Oka, J | 1 |
| Yamada, M | 1 |
| Saitoh, A | 1 |
| Luo, C | 1 |
| Zhang, YL | 1 |
| Luo, W | 1 |
| Zhou, FH | 1 |
| Li, CQ | 1 |
| Xu, JM | 1 |
| Dai, RP | 1 |
| Şahin, C | 1 |
| İmer Aras, H | 1 |
| Li, Y | 1 |
| Song, Z | 1 |
| Ding, Y | 1 |
| Xin, Y | 1 |
| Wu, T | 1 |
| Su, T | 1 |
| He, R | 1 |
| Tai, F | 1 |
| Lian, Z | 1 |
| Bahaaddini, M | 1 |
| Khatamsaz, S | 1 |
| Esmaeili-Mahani, S | 1 |
| Abbasnejad, M | 1 |
| Raoof, M | 1 |
| Rephaeli, A | 1 |
| Gil-Ad, I | 1 |
| Aharoni, A | 1 |
| Tarasenko, I | 1 |
| Tarasenko, N | 1 |
| Geffen, Y | 1 |
| Halbfinger, E | 1 |
| Nisemblat, Y | 1 |
| Weizman, A | 1 |
| Nudelman, A | 1 |
| Negrigo, A | 1 |
| Medeiros, M | 1 |
| Guinsburg, R | 1 |
| Covolan, L | 1 |
| Mendes-Gomes, J | 1 |
| Amaral, VC | 1 |
| Nunes-de-Souza, RL | 1 |
| HERTTING, G | 1 |
| STOKLASKA, E | 1 |
| Munro, G | 1 |
| Erichsen, HK | 1 |
| Mirza, NR | 1 |
| Morgan, WK | 1 |
| Rahman, AF | 2 |
| Takahashi, M | 2 |
| Kaneto, H | 2 |
| Sorg, BA | 2 |
| Willis, JR | 2 |
| Nowatka, TC | 1 |
| Ulibarri, C | 1 |
| See, RE | 2 |
| Westberg, HH | 2 |
| Hopkins, B | 1 |
| Saegusa, H | 2 |
| Kurihara, T | 2 |
| Zong, S | 2 |
| Minowa, O | 1 |
| Kazuno, A | 1 |
| Han, W | 2 |
| Matsuda, Y | 2 |
| Yamanaka, H | 1 |
| Osanai, M | 1 |
| Noda, T | 1 |
| Tanabe, T | 2 |
| Kazuno , A | 1 |
| Nonaka, T | 1 |
| Toriyama, H | 1 |
| Yu, YH | 1 |
| Blessing, WW | 1 |
| Ramos, A | 1 |
| Kangerski, AL | 1 |
| Basso, PF | 1 |
| Da Silva Santos, JE | 1 |
| Assreuy, J | 1 |
| Vendruscolo, LF | 1 |
| Takahashi, RN | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Subanesthetic Sevoflurane for Treatment-Resistant Depression: A Proof-of-Concept Trial[NCT05008939] | 15 participants (Anticipated) | Interventional | 2021-08-31 | Not yet recruiting | |||
| Placebo-Controlled Crossover Trial of Levetiracetam on Ethanol Intake[NCT01168687] | 46 participants (Actual) | Interventional | 2008-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The primary outcome of this study is to determine the effect of levetiracetam on alcohol consumption as measured by change in # of drinks during each treatment period. (NCT01168687)
Timeframe: During each 14 day treatment period
| Intervention | number of drinks per treatment period (Mean) |
|---|---|
| All Subjects (n = 46) Placebo | 41.2 |
| All Subjects (n = 46) Levetiracetam | 45.4 |
19 other studies available for formaldehyde and Anxiety
| Article | Year |
|---|---|
DOR(2)-selective but not DOR(1)-selective antagonist abolishes anxiolytic-like effects of the δ opioid receptor agonist KNT-127.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzylidene Compounds; Exploratory Behavior; Formaldehyde; Ma | 2014 |
Differential effects of general anesthetics on anxiety-like behavior in formalin-induced pain: involvement of ERK activation in the anterior cingulate cortex.
Topics: Anesthetics, Inhalation; Animals; Anxiety; Behavior, Animal; Extracellular Signal-Regulated MAP Kina | 2015 |
Influence of nasal pack removal on patients' anxiety after septoplasty.
Topics: Adolescent; Adult; Anxiety; Epistaxis; Female; Follow-Up Studies; Formaldehyde; Hemostatics; Humans; | 2015 |
Effects of formaldehyde exposure on anxiety-like and depression-like behavior, cognition, central levels of glucocorticoid receptor and tyrosine hydroxylase in mice.
Topics: Animals; Anxiety; Behavior, Animal; Brain; Cognition; Depression; Formaldehyde; Learning; Male; Memo | 2016 |
The role of trigeminal nucleus caudalis orexin 1 receptor in orofacial pain-induced anxiety in rat.
Topics: Animals; Anxiety; Benzoxazoles; Capsaicin; Disease Models, Animal; Exploratory Behavior; Facial Pain | 2016 |
Gamma-aminobutyric acid amides of nortriptyline and fluoxetine display improved pain suppressing activity.
Topics: Analgesics; Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Fluoxetine; Formaldehyde; gam | 2009 |
Long-term gender behavioral vulnerability after nociceptive neonatal formalin stimulation in rats.
Topics: Age Factors; Animals; Animals, Newborn; Anxiety; Exploratory Behavior; Female; Formaldehyde; Male; M | 2011 |
Ventrolateral periaqueductal gray lesion attenuates nociception but does not change anxiety-like indices or fear-induced antinociception in mice.
Topics: Animals; Anxiety; Behavior, Animal; Excitatory Amino Acid Agonists; Fear; Formaldehyde; Male; Maze L | 2011 |
[Influence of nervous and humoral factors on the formol-edema of rat paws].
Topics: Adrenalectomy; Animals; Anxiety; Edema; Extremities; Formaldehyde; Rats | 1958 |
Pharmacological comparison of anticonvulsant drugs in animal models of persistent pain and anxiety.
Topics: Analgesics; Animals; Anticonvulsants; Anxiety; Chronic Disease; Conditioning, Operant; Electroshock; | 2007 |
Health risks of urea formaldehyde foam insulation.
Topics: Anxiety; Building Codes; Canada; Facility Design and Construction; Formaldehyde; Humans; Urea | 1984 |
Morphine dependence with or without tolerance in formalin-treated mice: further evidence for the dissociation.
Topics: Analgesia; Animals; Anxiety; Disease Models, Animal; Drug Tolerance; Formaldehyde; Injections, Intra | 1994 |
Involvement of pain associated anxiety in the development of morphine tolerance in formalin treated mice.
Topics: Animals; Anxiety; Aspirin; Diazepam; Drug Tolerance; Flumazenil; Formaldehyde; Indomethacin; Inflamm | 1994 |
Proposed animal neurosensitization model for multiple chemical sensitivity in studies with formalin.
Topics: Animals; Anxiety; Avoidance Learning; Disease Models, Animal; Female; Formaldehyde; Memory; Models, | 1996 |
Repeated low-level formaldehyde exposure produces cross-sensitization to cocaine: possible relevance to chemical sensitivity in humans.
Topics: Anesthetics, Local; Animals; Anxiety; Body Weight; Cocaine; Female; Formaldehyde; Motor Activity; Mu | 1998 |
Altered pain responses in mice lacking alpha 1E subunit of the voltage-dependent Ca2+ channel.
Topics: Acetic Acid; Animals; Anxiety; Calcium; Calcium Channels, R-Type; Exploratory Behavior; Fear; Formal | 2000 |
Suppression of inflammatory and neuropathic pain symptoms in mice lacking the N-type Ca2+ channel.
Topics: Acetic Acid; Acoustic Stimulation; Animals; Anxiety; Behavior, Animal; Calcium Channel Blockers; Cal | 2001 |
Neurons in amygdala mediate ear pinna vasoconstriction elicited by unconditioned salient stimuli in conscious rabbits.
Topics: Amygdala; Animals; Anxiety; Attention; Conditioning, Psychological; Consciousness; Ear, External; Fo | 2001 |
Evaluation of Lewis and SHR rat strains as a genetic model for the study of anxiety and pain.
Topics: Animals; Anxiety; Blood Pressure; Disease Models, Animal; Female; Formaldehyde; Lighting; Male; Pain | 2002 |