Page last updated: 2024-10-18

formaldehyde and Aneuploid

formaldehyde has been researched along with Aneuploid in 23 studies

paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy

Research Excerpts

ExcerptRelevanceReference
"A recently published human study suggested that exposure to formaldehyde (FA) at the workplace might induce leukemia-specific aneuploidies (monosomy 7 and trisomy 8) in cultured myeloid progenitor cells."7.78Analysis of leukemia-specific aneuploidies in cultured myeloid progenitor cells in the absence and presence of formaldehyde exposure. ( Kuehner, S; Schlaier, M; Schwarz, K; Speit, G, 2012)
"Formaldehyde (FA) is an economically important industrial chemical to which millions of people worldwide are exposed environmentally and occupationally."5.42Chromosome-wide aneuploidy study of cultured circulating myeloid progenitor cells from workers occupationally exposed to formaldehyde. ( Beane-Freeman, L; Blair, A; Ge, Y; Guo, W; Hu, W; Huang, H; Hubbard, AE; Ji, Z; Lan, Q; Li, L; Liu, S; McHale, CM; Qiu, C; Rappaport, SM; Reiss, B; Rothman, N; Shen, M; Smith, MT; Tang, X; Vermeulen, R; Xiong, J; Zhang, L, 2015)
"Formaldehyde (FA) was tested for a potential aneugenic activity in mammalian cells."5.37Does formaldehyde induce aneuploidy? ( Kühner, S; Linsenmeyer, R; Schütz, P; Speit, G, 2011)
" Among exposed workers, peripheral blood cell counts were significantly lowered in a manner consistent with toxic effects on the bone marrow and leukemia-specific chromosome changes were significantly elevated in myeloid blood progenitor cells."5.36Occupational exposure to formaldehyde, hematotoxicity, and leukemia-specific chromosome changes in cultured myeloid progenitor cells. ( Alter, BP; Azuma, M; Blair, A; Fraumeni, JF; Freeman, LB; Galvan, N; Ge, Y; Guo, W; Hauptmann, M; Hayes, RB; Hua, M; Huang, H; Hubbard, AE; Ji, Z; Kim, S; Lan, Q; Li, L; Li, S; Liu, S; Moore, LE; Qiu, C; Rappaport, SM; Reiss, B; Rothman, N; Ruan, X; Shen, M; Smith, MT; Stewart, P; Tang, X; Vermeulen, R; Xie, Y; Xin, KX; Xiong, J; Zhang, L, 2010)
"A recently published human study suggested that exposure to formaldehyde (FA) at the workplace might induce leukemia-specific aneuploidies (monosomy 7 and trisomy 8) in cultured myeloid progenitor cells."3.78Analysis of leukemia-specific aneuploidies in cultured myeloid progenitor cells in the absence and presence of formaldehyde exposure. ( Kuehner, S; Schlaier, M; Schwarz, K; Speit, G, 2012)
"Formaldehyde (FA) was tested for a potential aneugenic activity in mammalian cells."1.37Does formaldehyde induce aneuploidy? ( Kühner, S; Linsenmeyer, R; Schütz, P; Speit, G, 2011)
" Among exposed workers, peripheral blood cell counts were significantly lowered in a manner consistent with toxic effects on the bone marrow and leukemia-specific chromosome changes were significantly elevated in myeloid blood progenitor cells."1.36Occupational exposure to formaldehyde, hematotoxicity, and leukemia-specific chromosome changes in cultured myeloid progenitor cells. ( Alter, BP; Azuma, M; Blair, A; Fraumeni, JF; Freeman, LB; Galvan, N; Ge, Y; Guo, W; Hauptmann, M; Hayes, RB; Hua, M; Huang, H; Hubbard, AE; Ji, Z; Kim, S; Lan, Q; Li, L; Li, S; Liu, S; Moore, LE; Qiu, C; Rappaport, SM; Reiss, B; Rothman, N; Ruan, X; Shen, M; Smith, MT; Stewart, P; Tang, X; Vermeulen, R; Xie, Y; Xin, KX; Xiong, J; Zhang, L, 2010)
"The criterium aneuploidy showed a sensitivity of 86% and a specificity of 100% in regards to identifying a malignant tumor, irrespective of the preparation method."1.29Cytophotometric DNA-analysis of bone-tumors. A new method for preparing formalin-fixed tissue and the regarding of DNA-malignancy grade and its prognostic value. ( Adler, CP; Herget, GW; Klemm, CE; Neuburger, M; Saur, S, 1996)
"Aneuploidy was identified in 100% of cases in group A using ICM (in comparison to 73% by FCM) and in 73% of group B using ICM (in comparison to 44% by FCM)."1.28DNA quantification of squamous cell carcinoma of the oesophagus by flow cytometry and cytophotometric image analysis using formalin fixed paraffin embedded tissue. ( Curran, B; Dorman, AM; Droogan, O; Hennessy, TP; Hourihane, DO; Leader, M; Walsh, TN, 1992)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (52.17)18.2507
2000's2 (8.70)29.6817
2010's9 (39.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pollice, AA1
McCoy, JP2
Shackney, SE1
Smith, CA1
Agarwal, J1
Burholt, DR1
Janocko, LE1
Hornicek, FJ1
Singh, SG1
Hartsock, RJ1
Mundt, KA1
Gallagher, AE1
Dell, LD1
Natelson, EA1
Boffetta, P1
Gentry, PR1
Gliem, TJ1
Aypar, U1
Lan, Q2
Smith, MT3
Tang, X2
Guo, W2
Vermeulen, R2
Ji, Z3
Hu, W1
Hubbard, AE2
Shen, M2
McHale, CM2
Qiu, C2
Liu, S2
Reiss, B2
Beane-Freeman, L1
Blair, A2
Ge, Y2
Xiong, J2
Li, L2
Rappaport, SM2
Huang, H2
Rothman, N2
Zhang, L3
Bersonda, J1
Tung, J1
Freeman, LB1
Hua, M1
Galvan, N1
Ruan, X1
Alter, BP1
Xin, KX1
Li, S1
Moore, LE1
Kim, S1
Xie, Y1
Hayes, RB1
Azuma, M1
Hauptmann, M1
Stewart, P1
Fraumeni, JF1
Speit, G3
Gelbke, HP1
Pallapies, D1
Morfeld, P1
Alvarez, K1
Kash, SF1
Lyons-Weiler, MA1
Kim, HJ1
Peterson, LE1
Mathai, B1
Hagenkord, JM1
Monzon, FA1
Kühner, S1
Linsenmeyer, R1
Schütz, P1
Kuehner, S1
Schlaier, M1
Schwarz, K1
van Dijk, MC1
Rombout, PD1
Boots-Sprenger, SH1
Straatman, H1
Bernsen, MR1
Ruiter, DJ1
Jeuken, JW1
Baretton, G1
Blasenbreu, S1
Li, X1
DePascale, T1
Löhrs, U1
Nylander, K1
Stenling, R1
Gustafsson, H1
Roos, G1
Albro, J1
Bauer, KD1
Hitchcock, CL1
Wittwer, CT1
Leers, MP1
Theunissen, PH1
Schutte, TB1
Ramaekers, FC1
Overton, WR1
Catalano, E1
Fejgin, MD1
Kidron, D1
Kedar, I1
Gaber, E1
Tepper, R1
Beyth, Y1
Amiel, A1
Adler, CP1
Neuburger, M1
Herget, GW1
Klemm, CE1
Saur, S1
Kelsch, RD1
Bhuiya, T1
Fuchs, A1
Gentile, P1
Kahn, MA1
Fantasia, JE1
Kamiya, N1
Yokose, T1
Kiyomatsu, Y1
Fahey, MT1
Kodama, T1
Mukai, K1
Fukunaga, M1
Dorman, AM1
Walsh, TN1
Droogan, O1
Curran, B1
Hourihane, DO1
Hennessy, TP1
Leader, M1
Kitaeva, LV1
Kitaev, EM1
Pimenova, MN1

Reviews

2 reviews available for formaldehyde and Aneuploid

ArticleYear
Does occupational exposure to formaldehyde cause hematotoxicity and leukemia-specific chromosome changes in cultured myeloid progenitor cells?
    Critical reviews in toxicology, 2017, Volume: 47, Issue:7

    Topics: Adult; Aneuploidy; Chromosomes; Cross-Sectional Studies; Formaldehyde; Hazardous Substances; Humans;

2017
Flow cytometric and clinicopathologic study of complete hydatidiform moles with special reference to the significance of cytometric aneuploidy.
    Gynecologic oncology, 2001, Volume: 81, Issue:1

    Topics: Adolescent; Adult; Aneuploidy; DNA, Neoplasm; Female; Flow Cytometry; Follow-Up Studies; Formaldehyd

2001

Other Studies

21 other studies available for formaldehyde and Aneuploid

ArticleYear
Sequential paraformaldehyde and methanol fixation for simultaneous flow cytometric analysis of DNA, cell surface proteins, and intracellular proteins.
    Cytometry, 1992, Volume: 13, Issue:4

    Topics: Aneuploidy; Animals; Cell Line; Cell Membrane Permeability; DNA; DNA, Neoplasm; Fixatives; Flow Cyto

1992
Development of a Chromosomal Microarray Test for the Detection of Abnormalities in Formalin-Fixed, Paraffin-Embedded Products of Conception Specimens.
    The Journal of molecular diagnostics : JMD, 2017, Volume: 19, Issue:6

    Topics: Abortion, Spontaneous; Aneuploidy; Chromosome Aberrations; Chromosome Disorders; Female; Formaldehyd

2017
Chromosome-wide aneuploidy study of cultured circulating myeloid progenitor cells from workers occupationally exposed to formaldehyde.
    Carcinogenesis, 2015, Volume: 36, Issue:1

    Topics: Adult; Aneuploidy; Case-Control Studies; Cells, Cultured; Chromosomes, Human; Cross-Sectional Studie

2015
Induction of centrosome amplification by formaldehyde, but not hydroquinone, in human lymphoblastoid TK6 cells.
    Environmental and molecular mutagenesis, 2015, Volume: 56, Issue:6

    Topics: Aneuploidy; Cell Line; Centrosome; Chromosome Aberrations; Dose-Response Relationship, Drug; Etoposi

2015
Occupational exposure to formaldehyde, hematotoxicity, and leukemia-specific chromosome changes in cultured myeloid progenitor cells.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2010, Volume: 19, Issue:1

    Topics: Adult; Aneuploidy; Blood Cell Count; Carcinogens; Cells, Cultured; Chromosomes, Human, Pair 7; Chrom

2010
Occupational exposure to formaldehyde, hematotoxicity and leukemia-specific chromosome changes in cultured myeloid progenitor cells.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2010, Volume: 19, Issue:7

    Topics: Adult; Aneuploidy; Blood Cell Count; Chromosomes, Human, Pair 7; Chromosomes, Human, Pair 8; Formald

2010
Reproducibility and performance of virtual karyotyping with SNP microarrays for the detection of chromosomal imbalances in formalin-fixed paraffin-embedded tissues.
    Diagnostic molecular pathology : the American journal of surgical pathology, part B, 2010, Volume: 19, Issue:3

    Topics: Adolescent; Aneuploidy; Child; Child, Preschool; Fixatives; Formaldehyde; Humans; Infant; Karyotypin

2010
Does formaldehyde induce aneuploidy?
    Mutagenesis, 2011, Volume: 26, Issue:6

    Topics: Aneuploidy; Animals; Bromodeoxyuridine; Cell Line; Cricetinae; Demecolcine; Formaldehyde; Humans; In

2011
Analysis of leukemia-specific aneuploidies in cultured myeloid progenitor cells in the absence and presence of formaldehyde exposure.
    Toxicological sciences : an official journal of the Society of Toxicology, 2012, Volume: 128, Issue:1

    Topics: Aneuploidy; Cells, Cultured; Formaldehyde; Humans; In Situ Hybridization, Fluorescence; Leukemia; My

2012
Multiplex ligation-dependent probe amplification for the detection of chromosomal gains and losses in formalin-fixed tissue.
    Diagnostic molecular pathology : the American journal of surgical pathology, part B, 2005, Volume: 14, Issue:1

    Topics: Aneuploidy; DNA, Neoplasm; Female; Formaldehyde; Humans; Male; Melanoma; Molecular Probe Techniques;

2005
[DNA cytometry using paraffin embedded tumor tissues. Comparison of flow cytometry (FCM) and image cytometry (ICM)].
    Zentralblatt fur Pathologie, 1994, Volume: 139, Issue:6

    Topics: Adenocarcinoma; Aneuploidy; Carcinoma; Coloring Agents; Diploidy; DNA, Neoplasm; Flow Cytometry; For

1994
Application of dual parameter analysis in flow cytometric DNA measurements of paraffin-embedded samples.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1994, Volume: 23, Issue:4

    Topics: Aneuploidy; Carcinoma, Squamous Cell; DNA, Neoplasm; Epithelium; Fixatives; Flow Cytometry; Formalde

1994
Improved DNA content histograms from formalin-fixed, paraffin-embedded liver tissue by proteinase K digestion.
    Cytometry, 1993, Volume: 14, Issue:6

    Topics: Aneuploidy; Artifacts; Autopsy; Cell Nucleus; DNA; Endopeptidase K; Fixatives; Flow Cytometry; Forma

1993
Bivariate cytokeratin/DNA flow cytometric analysis of paraffin-embedded samples from colorectal carcinomas.
    Cytometry, 1995, Sep-01, Volume: 21, Issue:1

    Topics: Aneuploidy; Colorectal Neoplasms; DNA, Neoplasm; Flow Cytometry; Formaldehyde; G1 Phase; Humans; Imm

1995
Method to make paraffin-embedded breast and lymph tissue mimic fresh tissue in DNA analysis.
    Cytometry, 1996, Jun-15, Volume: 26, Issue:2

    Topics: Aneuploidy; Breast; Chymotrypsin; DNA; Endopeptidases; Female; Fixatives; Formaldehyde; Humans; Lymp

1996
Genetic diagnosis from formalin-fixed fetal tissue using FISH: a new tool for genetic counseling in subsequent pregnancies.
    European journal of obstetrics, gynecology, and reproductive biology, 1996, Volume: 64, Issue:2

    Topics: Aneuploidy; Chromosome Aberrations; Chromosome Disorders; Feasibility Studies; Female; Fetal Disease

1996
Cytophotometric DNA-analysis of bone-tumors. A new method for preparing formalin-fixed tissue and the regarding of DNA-malignancy grade and its prognostic value.
    Pathology, research and practice, 1996, Volume: 192, Issue:5

    Topics: Age Factors; Aneuploidy; Bone Neoplasms; Cytophotometry; DNA, Neoplasm; Female; Formaldehyde; Humans

1996
Polymorphous low-grade adenocarcinoma: flow cytometric, p53, and PCNA analysis.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 1997, Volume: 84, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aneuploidy; Cell Division; Diploidy; DNA, Neoplasm; Female; Fixatives;

1997
Assessment of DNA content in formalin-fixed, paraffin-embedded tissue of lung cancer by laser scanning cytometer.
    Pathology international, 1999, Volume: 49, Issue:8

    Topics: Aneuploidy; Diploidy; DNA, Neoplasm; Fixatives; Flow Cytometry; Formaldehyde; Freezing; Humans; Imag

1999
DNA quantification of squamous cell carcinoma of the oesophagus by flow cytometry and cytophotometric image analysis using formalin fixed paraffin embedded tissue.
    Cytometry, 1992, Volume: 13, Issue:8

    Topics: Adult; Aged; Aneuploidy; Carcinoma, Squamous Cell; DNA, Neoplasm; Esophageal Neoplasms; Female; Fixa

1992
[The cytopathic and cytogenetic sequelae of chronic inhalational exposure to formaldehyde on female germ cells and bone marrow cells in rats].
    Tsitologiia, 1990, Volume: 32, Issue:12

    Topics: Administration, Inhalation; Aneuploidy; Animals; Bone Marrow; Chromosome Aberrations; Dose-Response

1990