formaldehyde has been researched along with Amyotrophic Lateral Sclerosis in 15 studies
paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
Excerpt | Relevance | Reference |
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"The aim of this study was to determine whether patients with amyotrophic lateral sclerosis (ALS) exhibit higher plasma levels of formaldehyde (FA) than controls, and to look for alterations in levels of FA precursors." | 7.96 | Plasma from some patients with amyotrophic lateral sclerosis exhibits elevated formaldehyde levels. ( Arachchige, BJ; Aylward, J; Henderson, R; Lee, A; McCombe, PA; Reed, S, 2020) |
"Prior studies have yielded inconsistent evidence regarding the association between formaldehyde exposure and amyotrophic lateral sclerosis (ALS)." | 7.85 | Occupational formaldehyde and amyotrophic lateral sclerosis. ( Gredal, O; Hansen, J; Kioumourtzoglou, MA; Seals, RM; Weisskopf, MG, 2017) |
"The aim of this study was to determine whether patients with amyotrophic lateral sclerosis (ALS) exhibit higher plasma levels of formaldehyde (FA) than controls, and to look for alterations in levels of FA precursors." | 3.96 | Plasma from some patients with amyotrophic lateral sclerosis exhibits elevated formaldehyde levels. ( Arachchige, BJ; Aylward, J; Henderson, R; Lee, A; McCombe, PA; Reed, S, 2020) |
"Prior studies have yielded inconsistent evidence regarding the association between formaldehyde exposure and amyotrophic lateral sclerosis (ALS)." | 3.85 | Occupational formaldehyde and amyotrophic lateral sclerosis. ( Gredal, O; Hansen, J; Kioumourtzoglou, MA; Seals, RM; Weisskopf, MG, 2017) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (6.67) | 18.7374 |
1990's | 1 (6.67) | 18.2507 |
2000's | 5 (33.33) | 29.6817 |
2010's | 5 (33.33) | 24.3611 |
2020's | 3 (20.00) | 2.80 |
Authors | Studies |
---|---|
Embacher, N | 1 |
Kaufmann, WA | 1 |
Beer, R | 1 |
Maier, H | 1 |
Jellinger, KA | 1 |
Poewe, W | 1 |
Ransmayr, G | 1 |
Newell, ME | 1 |
Adhikari, S | 1 |
Halden, RU | 1 |
Lee, A | 1 |
Arachchige, BJ | 1 |
Reed, S | 1 |
Henderson, R | 1 |
Aylward, J | 1 |
McCombe, PA | 1 |
Bellavia, A | 1 |
Dickerson, AS | 1 |
Rotem, RS | 1 |
Hansen, J | 2 |
Gredal, O | 2 |
Weisskopf, MG | 3 |
Seals, RM | 1 |
Kioumourtzoglou, MA | 1 |
Spencer, PS | 1 |
Pinkerton, LE | 1 |
Hein, MJ | 1 |
Meyers, A | 1 |
Kamel, F | 1 |
Wakabayashi, K | 1 |
Mori, F | 1 |
Kakita, A | 1 |
Takahashi, H | 1 |
Utsumi, J | 1 |
Sasaki, H | 1 |
Roberts, AL | 1 |
Johnson, NJ | 1 |
Cudkowicz, ME | 1 |
Eum, KD | 1 |
Beaulieux, F | 1 |
Berger, MM | 1 |
Tcheng, R | 1 |
Giraud, P | 1 |
Lina, B | 1 |
Gellein, K | 1 |
Garruto, RM | 1 |
Syversen, T | 1 |
Sjøbakk, TE | 1 |
Flaten, TP | 1 |
Usarek, E | 1 |
Gajewska, B | 1 |
Kaźmierczak, B | 1 |
Kuźma, M | 1 |
Dziewulska, D | 1 |
Barańczyk-Kuźma, A | 1 |
Kuehn, BM | 1 |
Dawson, G | 1 |
Stefansson, K | 1 |
Abe, K | 1 |
Fujimura, H | 1 |
Kobayashi, Y | 1 |
Fujita, N | 1 |
Yanagihara, T | 1 |
1 review available for formaldehyde and Amyotrophic Lateral Sclerosis
Article | Year |
---|---|
Systematic and state-of the science review of the role of environmental factors in Amyotrophic Lateral Sclerosis (ALS) or Lou Gehrig's Disease.
Topics: Amyotrophic Lateral Sclerosis; Animals; Formaldehyde; Humans; Mercury; Mice; Selenium; Zinc | 2022 |
14 other studies available for formaldehyde and Amyotrophic Lateral Sclerosis
Article | Year |
---|---|
Apoptosis signals in sporadic amyotrophic lateral sclerosis: an immunocytochemical study.
Topics: Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Apoptosis; bcl-2 Homologous Antagonist-Kille | 2001 |
Plasma from some patients with amyotrophic lateral sclerosis exhibits elevated formaldehyde levels.
Topics: Aged; Amyotrophic Lateral Sclerosis; Biomarkers; Female; Formaldehyde; Humans; Male; Methylamines; M | 2020 |
Joint and interactive effects between health comorbidities and environmental exposures in predicting amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Case-Control Studies; Environmental Exposure; Female; Formaldehyde; H | 2021 |
Occupational formaldehyde and amyotrophic lateral sclerosis.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Case-Control Studies; Denmark; Employment; Female; Forma | 2017 |
Formaldehyde, DNA damage, ALS and related neurodegenerative diseases.
Topics: Amyotrophic Lateral Sclerosis; DNA Damage; Formaldehyde; Humans; Neurodegenerative Diseases | 2018 |
Assessment of ALS mortality in a cohort of formaldehyde-exposed garment workers.
Topics: Amyotrophic Lateral Sclerosis; Cohort Studies; Female; Fixatives; Formaldehyde; Humans; Male; Occupa | 2013 |
Analysis of microRNA from archived formalin-fixed paraffin-embedded specimens of amyotrophic lateral sclerosis.
Topics: Adaptor Proteins, Signal Transducing; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Anteri | 2014 |
Job-related formaldehyde exposure and ALS mortality in the USA.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Cohort Studies; Female; Formaldehyde; Humans; Longitudin | 2016 |
RNA extraction and RT-PCR procedures adapted for the detection of enterovirus sequences from frozen and paraffin-embedded formalin-fixed spinal cord samples.
Topics: Amyotrophic Lateral Sclerosis; Cryopreservation; Enterovirus; Enterovirus Infections; Formaldehyde; | 2003 |
Concentrations of Cd, Co, Cu, Fe, Mn, Rb, V, and Zn in formalin-fixed brain tissue in amyotrophic lateral sclerosis and Parkinsonism-dementia complex of Guam determined by High-resolution ICP-MS.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Animals; Brain Chemistry; Cattle; Dementia; Female; Form | 2003 |
A study of glutathione S-transferase pi expression in central nervous system of subjects with amyotrophic lateral sclerosis using RNA extraction from formalin-fixed, paraffin-embedded material.
Topics: Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Blotting, Western; Case-Control Studi | 2005 |
Researchers identify neurological risks.
Topics: Abattoirs; Alcohol Drinking; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Cholinergic | 2008 |
Gangliosides of human spinal cord: aberrant composition of cords from patients with amyotrophic lateral sclerosis.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Chromatography, Thin Layer; Female; Fixatives; Formaldeh | 1984 |
Degeneration of the pyramidal tracts in patients with amyotrophic lateral sclerosis. A premortem and postmortem magnetic resonance imaging study.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Axons; Cadaver; Case-Control Studies; Female; Fixatives; | 1997 |