Page last updated: 2024-10-18

formaldehyde and Alloxan Diabetes

formaldehyde has been researched along with Alloxan Diabetes in 47 studies

paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy

Research Excerpts

ExcerptRelevanceReference
"We evaluated the effects of zonisamide on inflammatory and neuropathic pain using the mouse formalin test and streptozotocin (STZ)-induced diabetic mice with a reduced withdrawal threshold to mechanical stimuli, respectively."7.74Zonisamide suppresses pain symptoms of formalin-induced inflammatory and streptozotocin-induced diabetic neuropathy. ( Murakami, T; Ono, H; Tanabe, M, 2008)
"An excess of excitatory pathway activation via N-methyl-D-aspartate (NMDA) receptors has been described in neuropathic pain that responds poorly to morphine."7.71Magnesium increases morphine analgesic effect in different experimental models of pain. ( Begon, S; Dubray, C; Eschalier, A; Pickering, G, 2002)
"This study examined the effects of hyperglycemia and treatment with the aldose reductase inhibitor, Tolrestat, on the pain behavior evoked by injection of formalin into the dorsum of a single hind paw."7.69Tolrestat treatment prevents modification of the formalin test model of prolonged pain in hyperglycemic rats. ( Calcutt, NA; Malmberg, AB; Yaksh, TL; Yamamoto, T, 1994)
" Chronic administration of minocycline (40 and 80 mg/kg, i."5.37Minocycline attenuates the development of diabetic neuropathic pain: possible anti-inflammatory and anti-oxidant mechanisms. ( Dua, K; Kulkarni, SK; Pabreja, K; Padi, SS; Sharma, S, 2011)
"Rats developed tactile allodynia within days of the onset of diabetes and which persisted for up to 8 weeks."5.29Tactile allodynia and formalin hyperalgesia in streptozotocin-diabetic rats: effects of insulin, aldose reductase inhibition and lidocaine. ( Calcutt, NA; Chaplan, SR; Jorge, MC; Yaksh, TL, 1996)
"We evaluated the effects of zonisamide on inflammatory and neuropathic pain using the mouse formalin test and streptozotocin (STZ)-induced diabetic mice with a reduced withdrawal threshold to mechanical stimuli, respectively."3.74Zonisamide suppresses pain symptoms of formalin-induced inflammatory and streptozotocin-induced diabetic neuropathy. ( Murakami, T; Ono, H; Tanabe, M, 2008)
"An excess of excitatory pathway activation via N-methyl-D-aspartate (NMDA) receptors has been described in neuropathic pain that responds poorly to morphine."3.71Magnesium increases morphine analgesic effect in different experimental models of pain. ( Begon, S; Dubray, C; Eschalier, A; Pickering, G, 2002)
"This study examined the effects of hyperglycemia and treatment with the aldose reductase inhibitor, Tolrestat, on the pain behavior evoked by injection of formalin into the dorsum of a single hind paw."3.69Tolrestat treatment prevents modification of the formalin test model of prolonged pain in hyperglycemic rats. ( Calcutt, NA; Malmberg, AB; Yaksh, TL; Yamamoto, T, 1994)
" Chronic administration of minocycline (40 and 80 mg/kg, i."1.37Minocycline attenuates the development of diabetic neuropathic pain: possible anti-inflammatory and anti-oxidant mechanisms. ( Dua, K; Kulkarni, SK; Pabreja, K; Padi, SS; Sharma, S, 2011)
"Proglumide was ineffective by itself and it did not affect the antinociception induced by the cyclooxygenase inhibitors in non-diabetic rats."1.37Proglumide enhances the antinociceptive effect of cyclooxygenase inhibitors in diabetic rats in the formalin test. ( Aguilar-Mariscal, H; Bermúdez-Ocaña, DY; Blé-Castillo, JL; Díaz-Zagoya, JC; Flores-Murrieta, FJ; Frías, TR; Granados-Soto, V; Juárez-Rojop, IE, 2011)
"Neuropathic pain was induced by either ligation of left L5/L6 spinal nerves or administration of streptozotocin (50 mg/kg, i."1.33Benfotiamine relieves inflammatory and neuropathic pain in rats. ( Caram-Salas, NL; Granados-Soto, V; Medina-Santillán, R; Reyes-García, G; Rocha-González, HI; Sánchez-Ramírez, GM; Vidal-Cantú, GC, 2006)
") significantly inhibited phenylquinone-evoked writhing movements in mice, but within this dose range no clear dose-response correlation was found."1.32Analgesic effect of TT-232, a heptapeptide somatostatin analogue, in acute pain models of the rat and the mouse and in streptozotocin-induced diabetic mechanical allodynia. ( Almási, R; Bölcskei, K; Börzsei, R; Elekes, K; Helyes, Z; Kéri, G; Petho, G; Pintér, E; Szabó, A; Szolcsányi, J; Szuts, T, 2004)
"Gabapentin displays efficacy against abnormal sensory processing in diabetic rats and may be of benefit for treating painful diabetic neuropathy."1.30Gabapentin prevents hyperalgesia during the formalin test in diabetic rats. ( Calcutt, NA; Ceseña, RM, 1999)
" Following the chronic administration of methylamine, the urinary levels of both formaldehyde and malondialdehyde (a product from lipid peroxidation) are found to be substantially increased."1.30Simultaneous determination of formaldehyde and methylglyoxal in urine: involvement of semicarbazide-sensitive amine oxidase-mediated deamination in diabetic complications. ( Deng, Y; Yu, PH, 1999)
"ICI 222155 also prevented hyperalgesia in diabetic rats 21-60 min after formalin, whereas tolrestat suppressed activity in diabetic rats below controls and also suppressed activity in controls when given orally or intrathecally."1.29Different effects of two aldose reductase inhibitors on nociception and prostaglandin E. ( Calcutt, NA; Li, L; Malmberg, AB; Yaksh, TL, 1995)
" Chronic administration of methylamine enhances blood prorenin level, which strongly suggests that uncontrolled deamination of methylamine may be a risk factor for initiation of endothelial injury, and subsequent genesis of atherosclerosis."1.29Formaldehyde produced endogenously via deamination of methylamine. A potential risk factor for initiation of endothelial injury. ( Yu, PH; Zuo, DM, 1996)
"Rats developed tactile allodynia within days of the onset of diabetes and which persisted for up to 8 weeks."1.29Tactile allodynia and formalin hyperalgesia in streptozotocin-diabetic rats: effects of insulin, aldose reductase inhibition and lidocaine. ( Calcutt, NA; Chaplan, SR; Jorge, MC; Yaksh, TL, 1996)

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.13)18.7374
1990's19 (40.43)18.2507
2000's16 (34.04)29.6817
2010's9 (19.15)24.3611
2020's2 (4.26)2.80

Authors

AuthorsStudies
Wang, J1
Li, J1
Xu, L1
Tan, D1
Guo, R1
Lin, W1
Xu, H1
Liu, Q1
Song, X1
Wang, C1
Wang, X2
Ma, S1
Feng, Y1
Meng, X1
Liu, X1
Wang, W1
Lou, K1
Roa-Coria, JE1
Pineda-Farias, JB1
Barragán-Iglesias, P1
Quiñonez-Bastidas, GN1
Zúñiga-Romero, Á1
Huerta-Cruz, JC1
Reyes-García, JG1
Flores-Murrieta, FJ3
Granados-Soto, V6
Rocha-González, HI3
García-Hernández, L1
Navarrete-Vázquez, G1
González-Trujano, ME1
López-Muñoz, FJ1
Déciga-Campos, M1
Nacitarhan, C1
Minareci, E1
Sadan, G2
Silva, M1
Martins, D1
Charrua, A1
Piscitelli, F1
Tavares, I1
Morgado, C1
Di Marzo, V1
Huang, YH1
Hou, SY1
Cheng, JK1
Wu, CH1
Lin, CR1
Tanabe, M1
Murakami, T1
Ono, H1
Jolivalt, CG1
Mizisin, LM1
Nelson, A1
Cunha, JM2
Ramos, KM1
Bonke, D1
Calcutt, NA8
Pabreja, K1
Dua, K1
Sharma, S1
Padi, SS1
Kulkarni, SK1
Bermúdez-Ocaña, DY2
Aguilar-Mariscal, H1
Frías, TR1
Blé-Castillo, JL1
Díaz-Zagoya, JC2
Juárez-Rojop, IE2
Sazonova, OV1
Trofimovich, EM1
Koroshchenko, GA1
Ageeva, TA1
Aĭzman, RI1
Subotialov, MA1
Selivanova, SV1
Schreiber, AK1
Neufeld, M1
Jesus, CH1
Christianson, JA1
Ryals, JM2
McCarson, KE1
Wright, DE2
Tasatargil, A1
Szolcsányi, J1
Bölcskei, K1
Szabó, A1
Pintér, E1
Petho, G1
Elekes, K1
Börzsei, R1
Almási, R1
Szuts, T1
Kéri, G1
Helyes, Z1
Baluchnejadmojarad, T1
Roghani, M1
Roghani-Dehkordi, F1
Araiza-Saldaña, CI2
Reyes-García, G2
Pérez-Severiano, F1
Sánchez-Ramírez, GM1
Caram-Salas, NL2
Vidal-Cantú, GC1
Medina-Santillán, R1
Torres-López, JE1
Ortíz-López, JU1
Cruz-Vera, J1
Johnson, MS1
Arreola-Espino, R1
Urquiza-Marín, H1
Ambriz-Tututi, M1
Mixcoatl-Zecuatl, T1
Kamei, J7
Hitosugi, H5
Kasuya, Y2
Malmberg, AB5
Yamamoto, T1
Yaksh, TL4
Courteix, C1
Eschalier, A2
Lavarenne, J1
Li, L1
Yu, PH3
Zuo, DM2
Takeshita, N3
Yamaguchi, I3
Jorge, MC1
Chaplan, SR1
Kashiwazaki, T4
Nagase, H3
Ohsawa, M3
Ceseña, RM1
Taki, K2
Crijns, FR1
Wolffenbuttel, BH1
De Mey, JG1
Struijker Boudier, HA1
Deng, Y1
Stiller, C1
Gustafsson, H1
Kowaluk, EA1
Mikusa, J1
Wismer, CT1
Zhu, CZ1
Schweitzer, E1
Lynch, JJ1
Lee, CH1
Jiang, M1
Bhagwat, SS1
Gomtsyan, A1
McKie, J1
Cox, BF1
Polakowski, J1
Reinhart, G1
Williams, M1
Jarvis, MF1
Begon, S1
Pickering, G1
Dubray, C1
Freshwater, JD1
Svensson, CI1
Kato, R1
Gillette, JR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Magnesium Oral Supplementation to Reduce Pain in Patients With Severe Peripheral Arterial Occlusive Disease: The MAG-PAPER Randomized Clinical Trial[NCT02455726]150 participants (Anticipated)Interventional2015-09-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

47 other studies available for formaldehyde and Alloxan Diabetes

ArticleYear
A robust activatable two-photon fluorescent probe for endogenous formaldehyde biomarker visualization diagnosis and evaluation of diabetes mellitus.
    Analytica chimica acta, 2023, Jul-25, Volume: 1266

    Topics: Animals; Biomarkers; Diabetes Mellitus, Experimental; Fluorescent Dyes; Formaldehyde; HeLa Cells; Hu

2023
Fluorophore-Promoted Facile Deprotonation and Exocyclic Five-Membered Ring Cyclization for Selective and Dynamic Tracking of Labile Glyoxals.
    Analytical chemistry, 2020, 10-20, Volume: 92, Issue:20

    Topics: Animals; Arginine; Chromatography, High Pressure Liquid; Cyclization; Diabetes Mellitus; Diabetes Me

2020
Possible involvement of peripheral TRP channels in the hydrogen sulfide-induced hyperalgesia in diabetic rats.
    BMC neuroscience, 2019, Jan-03, Volume: 20, Issue:1

    Topics: Acetanilides; Analgesics; Animals; Capsaicin; Cystathionine beta-Synthase; Diabetes Mellitus, Experi

2019
Antihyperalgesic activity of a novel synthesized analogue of lidocaine in diabetic rats.
    The Journal of pharmacy and pharmacology, 2013, Volume: 65, Issue:5

    Topics: Amines; Analgesics; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Diabetes Complications;

2013
The effect of benfotiamine on mu-opioid receptor mediated antinociception in experimental diabetes.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2014, Volume: 122, Issue:3

    Topics: Analgesics; Analgesics, Opioid; Animals; Body Weight; Diabetes Mellitus, Experimental; Fentanyl; For

2014
Endovanilloid control of pain modulation by the rostroventromedial medulla in an animal model of diabetic neuropathy.
    Neuropharmacology, 2016, Volume: 107

    Topics: Amides; Amidohydrolases; Analgesics, Non-Narcotic; Animals; Arachidonic Acids; Capsaicin; Chronic Pa

2016
Pulsed radiofrequency attenuates diabetic neuropathic pain and suppresses formalin-evoked spinal glutamate release in rats.
    International journal of medical sciences, 2016, Volume: 13, Issue:12

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Formaldehyde; Glutamic Acid; Male;

2016
Zonisamide suppresses pain symptoms of formalin-induced inflammatory and streptozotocin-induced diabetic neuropathy.
    Journal of pharmacological sciences, 2008, Volume: 107, Issue:2

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Formaldehyde; Inflammation; Isoxazo

2008
B vitamins alleviate indices of neuropathic pain in diabetic rats.
    European journal of pharmacology, 2009, Jun-10, Volume: 612, Issue:1-3

    Topics: Aldehydes; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dose-Resp

2009
Minocycline attenuates the development of diabetic neuropathic pain: possible anti-inflammatory and anti-oxidant mechanisms.
    European journal of pharmacology, 2011, Jul-01, Volume: 661, Issue:1-3

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Behavior, Animal; Biomarkers; Blood Glucose; Body W

2011
Proglumide enhances the antinociceptive effect of cyclooxygenase inhibitors in diabetic rats in the formalin test.
    European journal of pharmacology, 2011, Aug-16, Volume: 664, Issue:1-3

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Cyclooxygenase Inhib

2011
[To question about integrated prevention of diabetes taking into account the technogenic factors of environment (experimental results)].
    Meditsina truda i promyshlennaia ekologiia, 2012, Issue:5

    Topics: Alloxan; Animals; Antioxidants; Curcuma; Diabetes Mellitus, Experimental; Drug Therapy, Combination;

2012
Peripheral antinociceptive effect of anandamide and drugs that affect the endocannabinoid system on the formalin test in normal and streptozotocin-diabetic rats.
    Neuropharmacology, 2012, Volume: 63, Issue:8

    Topics: Analgesics; Animals; Arachidonic Acids; Behavior, Animal; Capsaicin; Diabetes Mellitus, Experimental

2012
Beneficial actions of neurotrophin treatment on diabetes-induced hypoalgesia in mice.
    The journal of pain, 2003, Volume: 4, Issue:9

    Topics: Animals; Behavior, Animal; Blood Glucose; Body Weight; Cold Temperature; Diabetes Mellitus, Experime

2003
Reduction in [D-Ala2, NMePhe4, Gly-ol5]enkephalin-induced peripheral antinociception in diabetic rats: the role of the L-arginine/nitric oxide/cyclic guanosine monophosphate pathway.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:1

    Topics: Analgesics, Opioid; Animals; Arginine; Blood Glucose; Cyclic GMP; Diabetes Mellitus, Experimental; D

2004
Analgesic effect of TT-232, a heptapeptide somatostatin analogue, in acute pain models of the rat and the mouse and in streptozotocin-induced diabetic mechanical allodynia.
    European journal of pharmacology, 2004, Sep-13, Volume: 498, Issue:1-3

    Topics: Acute Disease; Analgesics; Animals; Behavior, Animal; Benzoquinones; Diabetes Mellitus, Experimental

2004
Antinociceptive effect of Teucrium polium leaf extract in the diabetic rat formalin test.
    Journal of ethnopharmacology, 2005, Feb-28, Volume: 97, Issue:2

    Topics: Analgesics; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Formaldehyde; Male

2005
Effect of diabetes on the mechanisms of intrathecal antinociception of sildenafil in rats.
    European journal of pharmacology, 2005, Dec-19, Volume: 527, Issue:1-3

    Topics: Analgesia; Animals; Blood Glucose; Body Weight; Carbazoles; Cyclic GMP-Dependent Protein Kinases; Di

2005
Benfotiamine relieves inflammatory and neuropathic pain in rats.
    European journal of pharmacology, 2006, Jan-13, Volume: 530, Issue:1-2

    Topics: Adjuvants, Immunologic; Administration, Oral; Animals; Diabetes Mellitus, Experimental; Dose-Respons

2006
Peripheral participation of cholecystokinin in the morphine-induced peripheral antinociceptive effect in non-diabetic and diabetic rats.
    Neuropharmacology, 2007, Volume: 52, Issue:3

    Topics: Animals; Area Under Curve; Cholecystokinin; Diabetes Mellitus, Experimental; Dose-Response Relations

2007
Diabetes-induced chemogenic hypoalgesia is paralleled by attenuated stimulus-induced fos expression in the spinal cord of diabetic mice.
    The journal of pain, 2007, Volume: 8, Issue:8

    Topics: Animals; Behavior, Animal; Cell Count; Diabetes Mellitus, Experimental; Disease Models, Animal; Form

2007
Melatonin reduces formalin-induced nociception and tactile allodynia in diabetic rats.
    European journal of pharmacology, 2007, Dec-22, Volume: 577, Issue:1-3

    Topics: Analgesics; Animals; Behavior, Animal; Diabetes Mellitus, Experimental; Female; Formaldehyde; Guanid

2007
Formalin-induced nociceptive responses in diabetic mice.
    Neuroscience letters, 1993, Jan-12, Volume: 149, Issue:2

    Topics: Analgesics; Animals; Behavior, Animal; Diabetes Mellitus, Experimental; Dose-Response Relationship,

1993
Effects of mexiletine on formalin-induced nociceptive responses in mice.
    Research communications in chemical pathology and pharmacology, 1993, Volume: 80, Issue:2

    Topics: Animals; Diabetes Mellitus, Experimental; Formaldehyde; Injections, Intraperitoneal; Injections, Spi

1993
Tolrestat treatment prevents modification of the formalin test model of prolonged pain in hyperglycemic rats.
    Pain, 1994, Volume: 58, Issue:3

    Topics: Aldehyde Reductase; Animals; Behavior, Animal; Body Weight; Diabetes Mellitus, Experimental; Female;

1994
Anti-nociceptive effects of the GM1 ganglioside derivative AGF 44 on the formalin test in normal and streptozotocin-diabetic rats.
    Neuroscience letters, 1993, Oct-14, Volume: 161, Issue:1

    Topics: Animals; Behavior, Animal; Diabetes Mellitus, Experimental; Escape Reaction; Female; Formaldehyde; G

1993
Streptozocin-induced diabetic rats: behavioural evidence for a model of chronic pain.
    Pain, 1993, Volume: 53, Issue:1

    Topics: Animals; Behavior, Animal; Blood Glucose; Chronic Disease; Diabetes Mellitus, Experimental; Disease

1993
Different effects of two aldose reductase inhibitors on nociception and prostaglandin E.
    European journal of pharmacology, 1995, Oct-16, Volume: 285, Issue:2

    Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Female; Formaldehyde; Hyperalgesia; In

1995
Formaldehyde produced endogenously via deamination of methylamine. A potential risk factor for initiation of endothelial injury.
    Atherosclerosis, 1996, Volume: 120, Issue:1-2

    Topics: Allyl Compounds; Amine Oxidase (Copper-Containing); Animals; Butylamines; Deamination; Diabetes Mell

1996
Meta-chlorophenylpiperazine attenuates formalin-induced nociceptive responses through 5-HT1/2 receptors in both normal and diabetic mice.
    British journal of pharmacology, 1995, Volume: 116, Issue:8

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Formaldehyde; Indoles; Ketanser

1995
Insulin attenuates formalin-induced nociceptive response in mice through a mechanism that is deranged by diabetes mellitus.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:1

    Topics: Analgesics; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Formaldehyde; Indoles;

1997
Tactile allodynia and formalin hyperalgesia in streptozotocin-diabetic rats: effects of insulin, aldose reductase inhibition and lidocaine.
    Pain, 1996, Volume: 68, Issue:2-3

    Topics: Aldehyde Reductase; Anesthetics, Local; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dia

1996
The role of spinal delta1-opioid receptors in inhibiting the formalin-induced nociceptive response in diabetic mice.
    European journal of pharmacology, 1997, May-12, Volume: 326, Issue:1

    Topics: Analgesics; Animals; Benzylidene Compounds; Diabetes Mellitus, Experimental; Dose-Response Relations

1997
Aminoguanidine inhibits semicarbazide-sensitive amine oxidase activity: implications for advanced glycation and diabetic complications.
    Diabetologia, 1997, Volume: 40, Issue:11

    Topics: Amine Oxidase (Copper-Containing); Animals; Aorta; Diabetes Mellitus, Experimental; Enzyme Inhibitor

1997
Antinociceptive effects of morphine were different between experimental and genetic diabetes.
    Pharmacology, biochemistry, and behavior, 1998, Volume: 60, Issue:4

    Topics: Analgesics, Opioid; Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dopamine Agents; Do

1998
Modulation of the formalin-induced nociceptive response by diabetes: possible involvement of protein kinase C.
    Brain research, 1998, Aug-24, Volume: 803, Issue:1-2

    Topics: Animals; Behavior, Animal; Diabetes Mellitus, Experimental; Disease Models, Animal; Enzyme Activatio

1998
Gabapentin prevents hyperalgesia during the formalin test in diabetic rats.
    Neuroscience letters, 1999, Mar-05, Volume: 262, Issue:2

    Topics: Acetates; Amines; Analgesics; Animals; Blood Glucose; Body Weight; Cyclohexanecarboxylic Acids; Diab

1999
Algogenic mediator-induced nociceptive response in diabetic mice.
    European journal of pharmacology, 1999, Mar-26, Volume: 369, Issue:3

    Topics: Animals; Benzylidene Compounds; Bradykinin; Diabetes Mellitus, Experimental; Dinoprost; Dose-Respons

1999
Antinociceptive effects of the ORL1 receptor agonist nociceptin/orphanin FQ in diabetic mice.
    European journal of pharmacology, 1999, Apr-09, Volume: 370, Issue:2

    Topics: Animals; Capsaicin; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Formaldehyde;

1999
Mechanical properties of mesenteric arteries in diabetic rats: consequences of outward remodeling.
    The American journal of physiology, 1999, Volume: 276, Issue:5

    Topics: Animals; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Fixatives; Formaldehyde; Hy

1999
Simultaneous determination of formaldehyde and methylglyoxal in urine: involvement of semicarbazide-sensitive amine oxidase-mediated deamination in diabetic complications.
    Journal of chromatographic science, 1999, Volume: 37, Issue:9

    Topics: Amine Oxidase (Copper-Containing); Animals; Chromatography, High Pressure Liquid; Diabetes Mellitus,

1999
Elevated substance-P-like immunoreactivity levels in spinal dialysates during the formalin test in normal and diabetic rats.
    Brain research, 2000, Feb-21, Volume: 856, Issue:1-2

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Formaldehyde; Hindlimb; Hot Tempera

2000
Modulation of the formalin-induced nociceptive response by diabetes: possible involvement of intracellular calcium.
    Brain research, 2000, Apr-17, Volume: 862, Issue:1-2

    Topics: Animals; Calcium; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disinfectants; Enzyme Inhi

2000
ABT-702 (4-amino-5-(3-bromophenyl)-7-(6-morpholino-pyridin- 3-yl)pyrido[2,3-d]pyrimidine), a novel orally effective adenosine kinase inhibitor with analgesic and anti-inflammatory properties. II. In vivo characterization in the rat.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:3

    Topics: Adenosine Kinase; Administration, Oral; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents,

2000
Magnesium increases morphine analgesic effect in different experimental models of pain.
    Anesthesiology, 2002, Volume: 96, Issue:3

    Topics: Analgesics, Opioid; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Drug Synergism;

2002
Elevated spinal cyclooxygenase and prostaglandin release during hyperalgesia in diabetic rats.
    Diabetes, 2002, Volume: 51, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Body Weight; Cyclooxygenase 1; Cycl

2002
Sex differences in the effects of abnormal physiological states on the metabolism of drugs by rat liver microsomes.
    The Journal of pharmacology and experimental therapeutics, 1965, Volume: 150, Issue:2

    Topics: Adrenalectomy; Adrenocorticotropic Hormone; Aminopyrine; Aniline Compounds; Animals; Castration; Dia

1965