formaldehyde has been researched along with Acute Pain in 22 studies
paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy
Acute Pain: Intensely discomforting, distressful, or agonizing sensation associated with trauma or disease, with well-defined location, character, and timing.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Opioid coadministration had a synergistic effect in the acute tonic pain (acetic acid writhing test), acute phasic pain (tail flick test) and inflammatory pain (orofacial formalin test)." | 7.79 | Systemic synergism between codeine and morphine in three pain models in mice. ( Miranda, HF; Noriega, V; Prieto, JC; Sierralta, F; Zepeda, RJ, 2013) |
| "Acute pain was determined using the hot plate test (thermal nociception) and the formalin test (inflammatory pain)." | 5.40 | The oral administration of trans-caryophyllene attenuates acute and chronic pain in mice. ( Andersen, ML; Carlini, EL; Gama, VS; Molska, GR; Paula-Freire, LI, 2014) |
| " Antinociceptive and antiedematogenic effects were evaluated by chemical (acetic acid-induced abdominal writhing, nociception and paw edema induced by formalin and glutamate, croton oil-induced ear edema) and thermal (tail immersion and hot-plate) tests." | 3.80 | Meloxicam-loaded nanocapsules have antinociceptive and antiedematogenic effects in acute models of nociception. ( Alves, MP; Fernandes, RS; Ianiski, FR; Luchese, C; Villalba, BT; Wilhelm, EA, 2014) |
| " Opioid coadministration had a synergistic effect in the acute tonic pain (acetic acid writhing test), acute phasic pain (tail flick test) and inflammatory pain (orofacial formalin test)." | 3.79 | Systemic synergism between codeine and morphine in three pain models in mice. ( Miranda, HF; Noriega, V; Prieto, JC; Sierralta, F; Zepeda, RJ, 2013) |
| "Ipsilateral, but not contralateral, pre-treatment (in μg/paw) with sumatriptan (10-300), methysergide (1-30) or dihydroergotamine (1-30) significantly prevented flinching behavior (at 1h) as well as secondary allodynia and hyperalgesia (at day 6) induced by formalin." | 3.79 | Role of 5-HT₁B/₁D receptors in the reduction of formalin-induced nociception and secondary allodynia/hyperalgesia produced by antimigraine drugs in rats. ( Argüelles, CF; Godínez-Chaparro, B; Granados-Soto, V; López-Santillán, FJ; Villalón, CM, 2013) |
| "Heat and mechanical hyperalgesia were evaluated by radiant heat and von Frey filament tests, respectively." | 1.91 | Mechanisms involved in the antinociceptive and anti-inflammatory effects of xanthotoxin. ( Guo, J; Song, Y; Tang, J; Tang, Z; Yang, Y; Yu, G; Zhu, C, 2023) |
| "Acute pain was determined using the hot plate test (thermal nociception) and the formalin test (inflammatory pain)." | 1.40 | The oral administration of trans-caryophyllene attenuates acute and chronic pain in mice. ( Andersen, ML; Carlini, EL; Gama, VS; Molska, GR; Paula-Freire, LI, 2014) |
| "Treatment with naloxone, L-arginine and glibenclamide reversed the effect of LPEF in glutamate test." | 1.39 | Antinociceptive effect of Lecythis pisonis Camb. (Lecythidaceae) in models of acute pain in mice. ( Almeida, FR; Brandão, MS; Chaves, MH; Ferreira, EL; Lima, DF; Oliveira, JP; Pereira, SS, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 16 (72.73) | 24.3611 |
| 2020's | 6 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Wilt, S | 1 |
| Kodani, S | 1 |
| Valencia, L | 1 |
| Hudson, PK | 1 |
| Sanchez, S | 1 |
| Quintana, T | 1 |
| Morisseau, C | 1 |
| Hammock, BD | 1 |
| Kandasamy, R | 1 |
| Pecic, S | 1 |
| Neves, ML | 1 |
| Karvat, J | 1 |
| Simões, RR | 1 |
| Speretta, GFF | 1 |
| Lataro, RM | 1 |
| da Silva, MD | 1 |
| Santos, ARS | 1 |
| Zhu, C | 1 |
| Yang, Y | 1 |
| Song, Y | 1 |
| Guo, J | 1 |
| Yu, G | 1 |
| Tang, J | 1 |
| Tang, Z | 1 |
| Shin, H | 1 |
| Kim, J | 1 |
| Choi, SR | 1 |
| Kang, DW | 1 |
| Moon, JY | 1 |
| Roh, DH | 1 |
| Bae, M | 1 |
| Hwang, J | 1 |
| Kim, HW | 1 |
| Lee, JY | 1 |
| Lee, GJ | 1 |
| Lee, PR | 1 |
| Won, CH | 1 |
| Kim, D | 1 |
| Kang, Y | 1 |
| Oh, SB | 1 |
| Rapacz, A | 1 |
| Rybka, S | 1 |
| Obniska, J | 1 |
| Jodłowska, A | 1 |
| Góra, M | 1 |
| Koczurkiewicz, P | 1 |
| Pękala, E | 1 |
| Siwek, A | 1 |
| Filipek, B | 1 |
| Jiang, ZJ | 1 |
| Li, QY | 1 |
| Zhang, YY | 1 |
| Zeng, MX | 1 |
| Hu, H | 1 |
| Zhang, FM | 1 |
| Bi, LB | 1 |
| Gu, JH | 1 |
| Liu, XJ | 1 |
| Nesterkina, M | 1 |
| Kravchenko, I | 1 |
| Kataoka, K | 1 |
| Hara, K | 1 |
| Haranishi, Y | 1 |
| Terada, T | 1 |
| Sata, T | 1 |
| Rios, ER | 1 |
| Rocha, NF | 1 |
| Carvalho, AM | 1 |
| Vasconcelos, LF | 1 |
| Dias, ML | 1 |
| de Sousa, DP | 1 |
| de Sousa, FC | 1 |
| Fonteles, MM | 1 |
| Miranda, HF | 1 |
| Noriega, V | 1 |
| Zepeda, RJ | 1 |
| Sierralta, F | 1 |
| Prieto, JC | 1 |
| Godínez-Chaparro, B | 1 |
| López-Santillán, FJ | 1 |
| Argüelles, CF | 1 |
| Villalón, CM | 1 |
| Granados-Soto, V | 1 |
| Torres-López, JE | 1 |
| Carmona-Díaz, E | 1 |
| Cortés-Peñaloza, JL | 1 |
| Guzmán-Priego, CG | 1 |
| Rocha-González, HI | 1 |
| Segawa, T | 1 |
| Miyakoshi, N | 1 |
| Kasukawa, Y | 1 |
| Aonuma, H | 1 |
| Tsuchie, H | 1 |
| Shimada, Y | 1 |
| Paula-Freire, LI | 1 |
| Andersen, ML | 1 |
| Gama, VS | 1 |
| Molska, GR | 1 |
| Carlini, EL | 1 |
| Nishijima, CM | 1 |
| Ganev, EG | 1 |
| Mazzardo-Martins, L | 2 |
| Martins, DF | 2 |
| Rocha, LR | 1 |
| Santos, AR | 2 |
| Hiruma-Lima, CA | 1 |
| Zambelli, VO | 1 |
| Gross, ER | 1 |
| Chen, CH | 1 |
| Gutierrez, VP | 1 |
| Cury, Y | 1 |
| Mochly-Rosen, D | 1 |
| Villalba, BT | 1 |
| Ianiski, FR | 1 |
| Wilhelm, EA | 1 |
| Fernandes, RS | 1 |
| Alves, MP | 1 |
| Luchese, C | 1 |
| Tochiki, KK | 1 |
| Maiarú, M | 1 |
| Norris, C | 1 |
| Hunt, SP | 1 |
| Géranton, SM | 1 |
| Hasani, AS | 1 |
| Soljakova, M | 1 |
| Jakupi, MH | 1 |
| Ustalar-Ozgen, SZ | 1 |
| Nucci, C | 1 |
| Stramosk, J | 1 |
| Brethanha, LC | 1 |
| Pizzolatti, MG | 1 |
| Brandão, MS | 1 |
| Pereira, SS | 1 |
| Lima, DF | 1 |
| Oliveira, JP | 1 |
| Ferreira, EL | 1 |
| Chaves, MH | 1 |
| Almeida, FR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Oxidative Stress and Surgical Recovery[NCT04732000] | Phase 2 | 21 participants (Actual) | Interventional | 2021-07-01 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
22 other studies available for formaldehyde and Acute Pain
| Article | Year |
|---|---|
Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors.
Topics: Acute Pain; Amidohydrolases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relatio | 2021 |
The antinociceptive effect of manual acupuncture in the auricular branch of the vagus nerve in visceral and somatic acute pain models and its laterality dependence.
Topics: Acupuncture Therapy; Acute Pain; Analgesics; Animals; Cholinergic Agents; Cholinergic Antagonists; F | 2022 |
Mechanisms involved in the antinociceptive and anti-inflammatory effects of xanthotoxin.
Topics: Acute Pain; Analgesics; Animals; Anti-Inflammatory Agents; Capsaicin; Chronic Pain; Formaldehyde; Ga | 2023 |
Antinociceptive effect of intermittent fasting via the orexin pathway on formalin-induced acute pain in mice.
Topics: Acute Pain; Analgesics; Animals; Corticosterone; Formaldehyde; Intermittent Fasting; Mice; Orexin Re | 2023 |
The analgesic effect of refeeding on acute and chronic inflammatory pain.
Topics: Acute Pain; Analgesics, Opioid; Animals; Chronic Pain; Disease Models, Animal; Eating; Food Deprivat | 2019 |
Analgesic and antiallodynic activity of novel anticonvulsant agents derived from 3-benzhydryl-pyrrolidine-2,5-dione in mouse models of nociceptive and neuropathic pain.
Topics: Acute Pain; Analgesics; Animals; Anticonvulsants; Disease Models, Animal; Formaldehyde; Hep G2 Cells | 2020 |
Deletion of MyD88 adaptor in nociceptor alleviates low-dose formalin-induced acute pain and persistent pain in mice.
Topics: Acute Pain; Animals; Chronic Pain; Formaldehyde; Mice; Mice, Knockout; Myeloid Differentiation Facto | 2021 |
Analgesic Activity of Novel GABA Esters after Transdermal Delivery.
Topics: Acute Pain; Administration, Cutaneous; Analgesics, Non-Narcotic; Animals; Capsaicin; Esters; Formald | 2016 |
The antinociceptive effect of SNAP5114, a gamma-aminobutyric acid transporter-3 inhibitor, in rat experimental pain models.
Topics: Acute Pain; Analgesics; Animals; Anisoles; Behavior, Animal; Chronic Pain; Constriction, Pathologic; | 2013 |
TRP and ASIC channels mediate the antinociceptive effect of citronellyl acetate.
Topics: Acetic Acid; Acid Sensing Ion Channels; Acute Pain; Administration, Oral; Analgesics; Animals; Disea | 2013 |
Systemic synergism between codeine and morphine in three pain models in mice.
Topics: Acetic Acid; Acute Pain; Analgesics, Opioid; Animals; Behavior, Animal; Codeine; Disease Models, Ani | 2013 |
Role of 5-HT₁B/₁D receptors in the reduction of formalin-induced nociception and secondary allodynia/hyperalgesia produced by antimigraine drugs in rats.
Topics: Acute Pain; Animals; Biphenyl Compounds; Chronic Pain; Dihydroergotamine; Disease Models, Animal; Dr | 2013 |
Antinociceptive synergy between diclofenac and morphine after local injection into the inflamed site.
Topics: Acute Pain; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; | 2013 |
Analgesic effects of minodronate on formalin-induced acute inflammatory pain in rats.
Topics: Acute Pain; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; | 2013 |
The oral administration of trans-caryophyllene attenuates acute and chronic pain in mice.
Topics: Acute Pain; Administration, Oral; Analgesics; Animals; Cannabis; Chronic Pain; Formaldehyde; Hot Tem | 2014 |
Citral: a monoterpene with prophylactic and therapeutic anti-nociceptive effects in experimental models of acute and chronic pain.
Topics: Acute Pain; Acyclic Monoterpenes; Analgesics; Animals; Capsaicin; Chronic Pain; Excitatory Amino Aci | 2014 |
Aldehyde dehydrogenase-2 regulates nociception in rodent models of acute inflammatory pain.
Topics: Acetaldehyde; Acute Pain; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Be | 2014 |
Meloxicam-loaded nanocapsules have antinociceptive and antiedematogenic effects in acute models of nociception.
Topics: Acute Pain; Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; | 2014 |
The mitogen and stress-activated protein kinase 1 regulates the rapid epigenetic tagging of dorsal horn neurons and nocifensive behaviour.
Topics: 5,6-Dihydroxytryptamine; Acute Pain; Adrenergic Uptake Inhibitors; Animals; Capsaicin; Desipramine; | 2016 |
Preemptive analgesic effect of diclofenac: experimental study in rats.
Topics: Acute Pain; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Diclofenac; Formalde | 2011 |
Oleaginous extract from the fruits Pterodon pubescens Benth induces antinociception in animal models of acute and chronic pain.
Topics: Acute Pain; Analgesics; Animals; Anti-Inflammatory Agents; Chronic Pain; Cold Temperature; Complex R | 2012 |
Antinociceptive effect of Lecythis pisonis Camb. (Lecythidaceae) in models of acute pain in mice.
Topics: Acetic Acid; Acute Pain; Analgesics; Animals; Arginine; Behavior, Animal; Capsaicin; Disease Models, | 2013 |