fomepizole has been researched along with Poisoning in 84 studies
Fomepizole: A pyrazole and competitive inhibitor of ALCOHOL DEHYDROGENASE that is used for the treatment of poisoning by ETHYLENE GLYCOL or METHANOL.
fomepizole : A member of the class of pyrazoles that is 1H-pyrazole substituted by a methyl group at position 4.
Poisoning: Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methanol and ethylene glycol poisoning may result in severe intoxication." | 9.11 | Plasma and tissue determination of 4-methylpyrazole for pharmacokinetic analysis in acute adult and pediatric methanol/ethylene glycol poisoning. ( Detaille, T; Di Fazio, V; Hantson, P; Haufroid, V; König, J; Vanbinst, R; Wallemacq, PE, 2004) |
| "Methanol poisoning may result in metabolic acidosis, blindness, and death." | 9.09 | Fomepizole for the treatment of methanol poisoning. ( Aaron, C; Brent, J; Kulig, K; McMartin, K; Phillips, S, 2001) |
| "Ethylene glycol poisoning causes metabolic acidosis and renal failure and may cause death." | 9.09 | Fomepizole for the treatment of ethylene glycol poisoning. Methylpyrazole for Toxic Alcohols Study Group. ( Brent, J; Burkhart, KK; Donovan, JW; Kulig, K; McMartin, K; Phillips, S; Wells, M, 1999) |
| "Fomepizole is now the antidote of choice in methanol poisoning." | 8.84 | Expert opinion: fomepizole may ameliorate the need for hemodialysis in methanol poisoning. ( Hovda, KE; Jacobsen, D, 2008) |
| "Methanol poisoning is not frequently observed in children; however, without treatment, serious intoxication can be complicated by visual impairment, coma, metabolic acidosis, respiratory and circulatory insufficiency and death." | 8.82 | Fomepizole as a therapeutic strategy in paediatric methanol poisoning. A case report and review of the literature. ( De Brabander, N; De Decker, K; De Weerdt, A; Jorens, PG; Wojciechowski, M, 2005) |
| "To assess the use of fomepizole in the treatment of ethylene glycol poisoning in the absence of hemodialysis." | 8.81 | Fomepizole as an antidote for ethylene glycol poisoning. ( Battistella, M, 2002) |
| "Almost all cases of acute methanol toxicity result from ingestion, though rarely cases of poisoning have followed inhalation or dermal absorption." | 8.81 | American Academy of Clinical Toxicology practice guidelines on the treatment of methanol poisoning. ( Barceloux, DG; Bond, GR; Cooper, H; Krenzelok, EP; Vale, JA, 2002) |
| "Ingestion of ethylene glycol may be an important contributor in patients with metabolic acidosis of unknown cause and subsequent renal failure." | 8.81 | Treatment of ethylene glycol poisoning. ( Archie, TE; Ferguson, DR; Piccaro, JC; Scalley, RD; Smart, ML, 2002) |
| "Ethylene glycol, a common antifreeze, coolant and industrial solvent, is responsible for many instances of accidental and intentional poisoning annually." | 8.81 | Current management of ethylene glycol poisoning. ( Brent, J, 2001) |
| "Ethylene glycol (EG) toxicity is an important cause of toxic alcohol poisoning in the USA with over 5,000 exposures reported annually." | 8.31 | Mass Poisoning From Ethylene Glycol at a U.S. Military Base. ( Banda, M; Forster, BM; Khayat, M; King, JD; Munoz, J; Owshalimpur, D; Petteys, SK; Shah, N; Sullivan, SB; Watson, M; White, WC, 2023) |
| "Ethylene glycol poisoning of incidental or suicidal intention can cause life-threatening metabolic acidosis, diverse secondary damage, and even lead to death." | 7.91 | [Antifreeze poisoning : The case of a patient with repeated ethylene glycol poisoning]. ( Becker, JU; Böll, B; Burst, V; Carvalho-Fiel, D; Kochanek, M; Prinz, J; Shimabukuro-Vornhagen, A; von Bergwelt-Baildon, M, 2019) |
| "During an outbreak of mass methanol poisoning in the Czech Republic in 2012-2014, we compared the total hospital costs and one-year medical costs in the patients treated with different antidotes (fomepizole versus ethanol) and modalities of hemodialysis (intermittent hemodialysis, IHD, versus continuous renal replacement therapy, CRRT)." | 7.85 | Cost-effectiveness of hospital treatment and outcomes of acute methanol poisoning during the Czech Republic mass poisoning outbreak. ( Balik, M; Belohlavek, J; Pelclova, D; Polak, F; Rulisek, J; Waldauf, P; Zakharov, S, 2017) |
| "Poisoning with methanol and ethylene glycol can cause serious morbidity and mortality." | 7.83 | Management of poisoning with ethylene glycol and methanol in the UK: a prospective study conducted by the National Poisons Information Service (NPIS). ( Bradberry, SM; Davies, J; Eddleston, M; Gilfillan, C; Jackson, G; Thanacoody, RH; Thomas, SH; Thompson, JP; Vale, AJ, 2016) |
| "Mass or cluster methanol poisonings are frequently reported from around the world." | 7.81 | Fomepizole versus ethanol in the treatment of acute methanol poisoning: Comparison of clinical effectiveness in a mass poisoning outbreak. ( Belacek, J; Eddleston, M; Hovda, KE; Komarc, M; Navratil, T; Pelclova, D; Zakharov, S, 2015) |
| "Ethylene glycol is a toxic organic solvent implicated in thousands of accidental and intentional poisonings each year." | 7.80 | Massive ethylene glycol poisoning triggers osmotic demyelination syndrome. ( Ahmed, A; Engelman, A; Krasowski, MD; Tschetter, PA, 2014) |
| "Diglycolic acid is associated with human DEG poisoning and may be a biomarker for poisoning." | 7.79 | Characterizing concentrations of diethylene glycol and suspected metabolites in human serum, urine, and cerebrospinal fluid samples from the Panama DEG mass poisoning. ( Bartels, MJ; Flanders, WD; Hunt, DR; Lewis, LS; McGeehin, MA; McMartin, KE; Perala, A; Schier, JG, 2013) |
| " There are few published cases worldwide of EG poisoning in children managed with fomepizole." | 7.78 | Antifreeze on a freezing morning: ethylene glycol poisoning in a 2-year-old. ( Duncan, D; Hann, G; Sohi, D; Sudhir, G; West, P, 2012) |
| "Fomepizole is the antidote of choice in toxic alcohol poisonings." | 7.77 | Studies on ethylene glycol poisoning: one patient - 154 admissions. ( Brørs, O; Hovda, KE; Jacobsen, D; Julsrud, J; Øvrebø, S, 2011) |
| "The management of methanol poisoning includes early antidote therapy to inhibit the metabolism of methanol to formate." | 7.74 | Methanol poisoning: the duality between 'fast and cheap' and 'slow and expensive'. ( Anseeuw, K; Legrand, A; Sabbe, MB, 2008) |
| "We report the case of a patient suspected of voluntary massive poisoning by ethylene glycol." | 7.73 | Prehospital diagnosis of massive ethylene glycol poisoning and use of an early antidote. ( Adnet, F; Amathieu, R; Borron, SW; Lapostolle, F; Merouani, M; Smail, N, 2006) |
| "Although not yet approved for this indication in the child, fomepizole seemed safe and effective in a case of severe ethylene glycol poisoning, without the need for hemodialysis." | 7.72 | Fomepizole alone for severe infant ethylene glycol poisoning. ( Clément de Cléty, S; Dembour, G; Detaille, T; Hantson, P; Vanbinst, R; Wallemacq, P, 2004) |
| "To illustrate the safety and efficacy of fomepizole in a case of methanol poisoning with initial visual impairment." | 7.71 | Fomepizole therapy for reversal of visual impairment after methanol poisoning: a case documented by visual evoked potentials investigation. ( Essama Mbia, JJ; Guérit, JM; Hantson, P; Haufroid, V, 2002) |
| "Poisoning with ethylene glycol causes severe metabolic acidosis and renal failure, and is potentially lethal if not treated rapidly." | 7.71 | [Severe ethylene glycol poisoning treated wtih fomepizole (4-methylpyrazole)]. ( Aakervik, O; Jacobsen, D; Svendsen, J, 2002) |
| "Diethylene glycol (DEG), a commonly used solvent, has been implicated in multiple poisoning deaths, the most recent being the Haitian acetaminophen tragedy." | 7.70 | Childhood diethylene glycol poisoning treated with alcohol dehydrogenase inhibitor fomepizole and hemodialysis. ( Brophy, PD; Bunchman, TE; Gardner, J; Smoyer, WE; Tenenbein, M, 2000) |
| "Fomepizole (4-methylpyrazole, 4-MP, Antizol) is a potent inhibitor of alcohol dehydrogenase that was approved recently by the US Food and Drug Administration (FDA) for the treatment of ethylene glycol poisoning." | 7.70 | American Academy of Clinical Toxicology Practice Guidelines on the Treatment of Ethylene Glycol Poisoning. Ad Hoc Committee. ( Barceloux, DG; Krenzelok, EP; Olson, K; Watson, W, 1999) |
| "Since the use of 4-methylpyrazole (4-MP) in the treatment of humans with methanol poisoning is poorly documented, we report two cases of acute methanol intoxication partially treated by this potent alcohol dehydrogenase (ADH) inhibitor." | 7.70 | Two cases of acute methanol poisoning partially treated by oral 4-methylpyrazole. ( Brau, M; Hantson, P; Haufroid, V; Mahieu, P; Vanbinst, R; Wallemacq, P, 1999) |
| "Treatment of human methanol poisoning with the alcohol dehydrogenase inhibitor, 4-methylpyrazole (fomepizole), has not been previously described." | 7.69 | Treatment of methanol poisoning with intravenous 4-methylpyrazole. ( Aaron, CK; Brent, J; Burns, MJ; Graudins, A; McMartin, K, 1997) |
| " The dosage of antidotes (fomepizole or ethanol) needs to be adjusted during ECTR." | 7.01 | Extracorporeal treatment for ethylene glycol poisoning: systematic review and recommendations from the EXTRIP workgroup. ( Bird, S; Ghannoum, M; Gosselin, S; Hassanian-Moghaddam, H; Hoffman, RS; Kallab, S; Lavergne, V; Mégarbane, B; Rif, M; Roberts, DM; Wood, DM, 2023) |
| "Ethylene glycol is a toxic alcohol which may induce significant toxicity when ingested accidentally or intentionally." | 6.72 | The three biological gaps and hyperoxaluria in ethylene glycol poisoning: case presentation and review. ( Ahmad, Y; Chiche, JD; Kissling, S; Liaudet, L; Ltaief, Z; Torrent, C, 2021) |
| "Diethylene glycol (DEG) is a clear, colorless, practically odorless, viscous, hygroscopic liquid with a sweetish taste." | 6.45 | Diethylene glycol poisoning. ( Beasley, DM; Schep, LJ; Slaughter, RJ; Temple, WA, 2009) |
| "Diagnosis of poisoning is based on detection of ethylene glycol in plasma or serum, but a challenge remains that acute toxicology service is only available at major hospital laboratories using gas chromatography." | 5.56 | [Simplified laboratory analysis of ethylene glycol allows improved management of poisoning cases]. ( Hansson, T; Helander, A; Nordmark Grass, J; Villen, T, 2020) |
| "Fomepizole has not been studied adequately in the pediatric population." | 5.31 | Fomepizole treatment of ethylene glycol poisoning in an infant. ( Aviles, SR; Baum, CR; Goldstein, CA; Langman, CB; Makar, JK; Oker, EE, 2000) |
| "EG poisoning was treated efficiently by 4-MP without recourse to hemodialysis." | 5.30 | Ethylene glycol poisoning in a child treated with 4-methylpyrazole. ( Briand, M; Caubet, A; Harry, P; Jobard, E; Turcant, A, 1998) |
| "Methanol and ethylene glycol poisoning may result in severe intoxication." | 5.11 | Plasma and tissue determination of 4-methylpyrazole for pharmacokinetic analysis in acute adult and pediatric methanol/ethylene glycol poisoning. ( Detaille, T; Di Fazio, V; Hantson, P; Haufroid, V; König, J; Vanbinst, R; Wallemacq, PE, 2004) |
| "Methanol poisoning may result in metabolic acidosis, blindness, and death." | 5.09 | Fomepizole for the treatment of methanol poisoning. ( Aaron, C; Brent, J; Kulig, K; McMartin, K; Phillips, S, 2001) |
| "Ethylene glycol poisoning causes metabolic acidosis and renal failure and may cause death." | 5.09 | Fomepizole for the treatment of ethylene glycol poisoning. Methylpyrazole for Toxic Alcohols Study Group. ( Brent, J; Burkhart, KK; Donovan, JW; Kulig, K; McMartin, K; Phillips, S; Wells, M, 1999) |
| "Ethylene glycol (EG) and methanol poisoning can cause life-threatening complications." | 4.90 | Ethylene glycol or methanol intoxication: which antidote should be used, fomepizole or ethanol? ( de Lange, DW; Meulenbelt, J; Rietjens, SJ, 2014) |
| "Fomepizole is now the antidote of choice in methanol poisoning." | 4.84 | Expert opinion: fomepizole may ameliorate the need for hemodialysis in methanol poisoning. ( Hovda, KE; Jacobsen, D, 2008) |
| "Acute methanol poisoning is mainly the consequence of voluntary or accidental ingestion." | 4.83 | [Acute methanol intoxication: physiopathology, prognosis and treatment]. ( Hantson, PE, 2006) |
| "Methanol poisoning is not frequently observed in children; however, without treatment, serious intoxication can be complicated by visual impairment, coma, metabolic acidosis, respiratory and circulatory insufficiency and death." | 4.82 | Fomepizole as a therapeutic strategy in paediatric methanol poisoning. A case report and review of the literature. ( De Brabander, N; De Decker, K; De Weerdt, A; Jorens, PG; Wojciechowski, M, 2005) |
| "Ethylene glycol, a common antifreeze, coolant and industrial solvent, is responsible for many instances of accidental and intentional poisoning annually." | 4.81 | Current management of ethylene glycol poisoning. ( Brent, J, 2001) |
| "Ingestion of ethylene glycol may be an important contributor in patients with metabolic acidosis of unknown cause and subsequent renal failure." | 4.81 | Treatment of ethylene glycol poisoning. ( Archie, TE; Ferguson, DR; Piccaro, JC; Scalley, RD; Smart, ML, 2002) |
| "Almost all cases of acute methanol toxicity result from ingestion, though rarely cases of poisoning have followed inhalation or dermal absorption." | 4.81 | American Academy of Clinical Toxicology practice guidelines on the treatment of methanol poisoning. ( Barceloux, DG; Bond, GR; Cooper, H; Krenzelok, EP; Vale, JA, 2002) |
| "To systematically review English-language articles on fomepizole administration in patients with ethylene glycol poisoning." | 4.81 | Role of fomepizole in the management of ethylene glycol toxicity. ( Druteika, DP; Ensom, MH; Zed, PJ, 2002) |
| "To assess the use of fomepizole in the treatment of ethylene glycol poisoning in the absence of hemodialysis." | 4.81 | Fomepizole as an antidote for ethylene glycol poisoning. ( Battistella, M, 2002) |
| "Ethylene glycol (EG) toxicity is an important cause of toxic alcohol poisoning in the USA with over 5,000 exposures reported annually." | 4.31 | Mass Poisoning From Ethylene Glycol at a U.S. Military Base. ( Banda, M; Forster, BM; Khayat, M; King, JD; Munoz, J; Owshalimpur, D; Petteys, SK; Shah, N; Sullivan, SB; Watson, M; White, WC, 2023) |
| "Ethylene glycol poisoning of incidental or suicidal intention can cause life-threatening metabolic acidosis, diverse secondary damage, and even lead to death." | 3.91 | [Antifreeze poisoning : The case of a patient with repeated ethylene glycol poisoning]. ( Becker, JU; Böll, B; Burst, V; Carvalho-Fiel, D; Kochanek, M; Prinz, J; Shimabukuro-Vornhagen, A; von Bergwelt-Baildon, M, 2019) |
| "During an outbreak of mass methanol poisoning in the Czech Republic in 2012-2014, we compared the total hospital costs and one-year medical costs in the patients treated with different antidotes (fomepizole versus ethanol) and modalities of hemodialysis (intermittent hemodialysis, IHD, versus continuous renal replacement therapy, CRRT)." | 3.85 | Cost-effectiveness of hospital treatment and outcomes of acute methanol poisoning during the Czech Republic mass poisoning outbreak. ( Balik, M; Belohlavek, J; Pelclova, D; Polak, F; Rulisek, J; Waldauf, P; Zakharov, S, 2017) |
| "Poisoning with methanol and ethylene glycol can cause serious morbidity and mortality." | 3.83 | Management of poisoning with ethylene glycol and methanol in the UK: a prospective study conducted by the National Poisons Information Service (NPIS). ( Bradberry, SM; Davies, J; Eddleston, M; Gilfillan, C; Jackson, G; Thanacoody, RH; Thomas, SH; Thompson, JP; Vale, AJ, 2016) |
| "Ethylene glycol is a toxic organic solvent implicated in thousands of accidental and intentional poisonings each year." | 3.80 | Massive ethylene glycol poisoning triggers osmotic demyelination syndrome. ( Ahmed, A; Engelman, A; Krasowski, MD; Tschetter, PA, 2014) |
| "Diglycolic acid is associated with human DEG poisoning and may be a biomarker for poisoning." | 3.79 | Characterizing concentrations of diethylene glycol and suspected metabolites in human serum, urine, and cerebrospinal fluid samples from the Panama DEG mass poisoning. ( Bartels, MJ; Flanders, WD; Hunt, DR; Lewis, LS; McGeehin, MA; McMartin, KE; Perala, A; Schier, JG, 2013) |
| " There are few published cases worldwide of EG poisoning in children managed with fomepizole." | 3.78 | Antifreeze on a freezing morning: ethylene glycol poisoning in a 2-year-old. ( Duncan, D; Hann, G; Sohi, D; Sudhir, G; West, P, 2012) |
| "Fomepizole is the antidote of choice in toxic alcohol poisonings." | 3.77 | Studies on ethylene glycol poisoning: one patient - 154 admissions. ( Brørs, O; Hovda, KE; Jacobsen, D; Julsrud, J; Øvrebø, S, 2011) |
| "The management of methanol poisoning includes early antidote therapy to inhibit the metabolism of methanol to formate." | 3.74 | Methanol poisoning: the duality between 'fast and cheap' and 'slow and expensive'. ( Anseeuw, K; Legrand, A; Sabbe, MB, 2008) |
| "Ethylene glycol and methanol ingestions are relatively uncommon but potentially lethal poisonings." | 3.74 | The management of severe toxic alcohol ingestions at a tertiary care center after the introduction of fomepizole. ( Green, R, 2007) |
| "We report the case of a patient suspected of voluntary massive poisoning by ethylene glycol." | 3.73 | Prehospital diagnosis of massive ethylene glycol poisoning and use of an early antidote. ( Adnet, F; Amathieu, R; Borron, SW; Lapostolle, F; Merouani, M; Smail, N, 2006) |
| "Knowledge on methanol poisoning does mainly come from clinical studies." | 3.73 | Methanol outbreak in Norway 2002-2004: epidemiology, clinical features and prognostic signs. ( Dunlop, O; Hovda, KE; Hunderi, OH; Jacobsen, D; Rudberg, N; Tafjord, AB, 2005) |
| "To illustrate the safety and efficacy of fomepizole in a case of methanol poisoning with initial visual impairment." | 3.71 | Fomepizole therapy for reversal of visual impairment after methanol poisoning: a case documented by visual evoked potentials investigation. ( Essama Mbia, JJ; Guérit, JM; Hantson, P; Haufroid, V, 2002) |
| "Since the use of 4-methylpyrazole (4-MP) in the treatment of humans with methanol poisoning is poorly documented, we report two cases of acute methanol intoxication partially treated by this potent alcohol dehydrogenase (ADH) inhibitor." | 3.70 | Two cases of acute methanol poisoning partially treated by oral 4-methylpyrazole. ( Brau, M; Hantson, P; Haufroid, V; Mahieu, P; Vanbinst, R; Wallemacq, P, 1999) |
| "Fomepizole (4-methylpyrazole, 4-MP, Antizol) is a potent inhibitor of alcohol dehydrogenase that was approved recently by the US Food and Drug Administration (FDA) for the treatment of ethylene glycol poisoning." | 3.70 | American Academy of Clinical Toxicology Practice Guidelines on the Treatment of Ethylene Glycol Poisoning. Ad Hoc Committee. ( Barceloux, DG; Krenzelok, EP; Olson, K; Watson, W, 1999) |
| " This method is easy to perform and has practical interest for clinicians who need to monitor in emergency 4-MP levels in ethylene glycol and methanol poisonings." | 3.69 | High-performance liquid chromatographic determination of 4-methylpyrazole in plasma and in dialysate. ( Allain, P; Harry, P; Jobard, E; Le Bouil, A; Turcant, A, 1997) |
| "Treatment of human methanol poisoning with the alcohol dehydrogenase inhibitor, 4-methylpyrazole (fomepizole), has not been previously described." | 3.69 | Treatment of methanol poisoning with intravenous 4-methylpyrazole. ( Aaron, CK; Brent, J; Burns, MJ; Graudins, A; McMartin, K, 1997) |
| " The dosage of antidotes (fomepizole or ethanol) needs to be adjusted during ECTR." | 3.01 | Extracorporeal treatment for ethylene glycol poisoning: systematic review and recommendations from the EXTRIP workgroup. ( Bird, S; Ghannoum, M; Gosselin, S; Hassanian-Moghaddam, H; Hoffman, RS; Kallab, S; Lavergne, V; Mégarbane, B; Rif, M; Roberts, DM; Wood, DM, 2023) |
| "Ethylene glycol is a toxic alcohol which may induce significant toxicity when ingested accidentally or intentionally." | 2.72 | The three biological gaps and hyperoxaluria in ethylene glycol poisoning: case presentation and review. ( Ahmad, Y; Chiche, JD; Kissling, S; Liaudet, L; Ltaief, Z; Torrent, C, 2021) |
| "The information on burden of alcohol abuse in Iran is scarce." | 2.53 | A Brief Review on Toxic Alcohols: Management Strategies. ( Hassanian-Moghaddam, H; Zamani, N, 2016) |
| "Diethylene glycol (DEG) is a clear, colorless, practically odorless, viscous, hygroscopic liquid with a sweetish taste." | 2.45 | Diethylene glycol poisoning. ( Beasley, DM; Schep, LJ; Slaughter, RJ; Temple, WA, 2009) |
| " Although initial response to all pediatric poisonings begins with basic stabilization, knowledge of specific antidotes, their mechanisms of action, safety profile in pediatrics, and dosing regimens can be life-saving for pediatric victims of nerve gas exposure, acetaminophen toxicity, methanol and ethylene glycol ingestion, and snakebites." | 2.43 | Update on antidotes for pediatric poisoning. ( Liebelt, EL; White, ML, 2006) |
| "Ethylene glycol is a serious toxin that children frequently ingest." | 2.40 | Novel therapies for ethylene glycol intoxication. ( Wiley, JF, 1999) |
| " Methanol toxicity initially is not characterized by severe toxic manifestations." | 2.38 | Methanol toxicity. Agency for Toxic Substances and Disease Registry. ( , 1993) |
| "Diethylene glycol (DEG) is an industrial solvent with many uses, including brake fluids." | 1.72 | Symptomatic Diethylene Glycol Ingestion Successfully Treated with Fomepizole Monotherapy. ( Clark, RF; Corbett, B; Lasoff, DR; Seltzer, JA, 2022) |
| "Diagnosis of poisoning is based on detection of ethylene glycol in plasma or serum, but a challenge remains that acute toxicology service is only available at major hospital laboratories using gas chromatography." | 1.56 | [Simplified laboratory analysis of ethylene glycol allows improved management of poisoning cases]. ( Hansson, T; Helander, A; Nordmark Grass, J; Villen, T, 2020) |
| "Treatment for ethylene glycol poisoning typically includes basic supportive care, alcohol dehydrogenase inhibition, and hemodialysis." | 1.34 | Ethylene glycol ingestion treated only with fomepizole. ( Keyes, DC; Lee, YC; Shepherd, G; Velez, LI, 2007) |
| "EG poisoning was treated efficiently by 4-MP without recourse to hemodialysis." | 1.30 | Ethylene glycol poisoning in a child treated with 4-methylpyrazole. ( Briand, M; Caubet, A; Harry, P; Jobard, E; Turcant, A, 1998) |
| "Ethylene glycol intoxication was confirmed in 37 dogs." | 1.29 | Safety and efficacy of 4-methylpyrazole for treatment of suspected or confirmed ethylene glycol intoxication in dogs: 107 cases (1983-1995). ( Connally, HE; Forney, SD; Grauer, GF; Hamar, DW; Thrall, MA, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 16 (19.05) | 18.2507 |
| 2000's | 42 (50.00) | 29.6817 |
| 2010's | 20 (23.81) | 24.3611 |
| 2020's | 6 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Ahmad, Y | 1 |
| Kissling, S | 1 |
| Torrent, C | 1 |
| Chiche, JD | 1 |
| Liaudet, L | 1 |
| Ltaief, Z | 1 |
| Beaulieu, J | 1 |
| Roberts, DM | 2 |
| Gosselin, S | 2 |
| Hoffman, RS | 2 |
| Lavergne, V | 2 |
| Hovda, KE | 5 |
| Megarbane, B | 4 |
| Lung, D | 1 |
| Thanacoody, R | 1 |
| Ghannoum, M | 2 |
| Seltzer, JA | 1 |
| Corbett, B | 1 |
| Lasoff, DR | 1 |
| Clark, RF | 1 |
| Shah, N | 1 |
| Khayat, M | 1 |
| Owshalimpur, D | 1 |
| Banda, M | 1 |
| Munoz, J | 1 |
| White, WC | 1 |
| Forster, BM | 1 |
| Petteys, SK | 1 |
| Sullivan, SB | 1 |
| Watson, M | 1 |
| King, JD | 1 |
| Hassanian-Moghaddam, H | 2 |
| Rif, M | 1 |
| Kallab, S | 1 |
| Bird, S | 1 |
| Wood, DM | 1 |
| Helander, A | 1 |
| Villen, T | 1 |
| Hansson, T | 1 |
| Nordmark Grass, J | 1 |
| Prinz, J | 1 |
| Böll, B | 1 |
| von Bergwelt-Baildon, M | 1 |
| Burst, V | 1 |
| Becker, JU | 1 |
| Carvalho-Fiel, D | 1 |
| Shimabukuro-Vornhagen, A | 1 |
| Kochanek, M | 1 |
| Gau, N | 1 |
| Scott, MG | 1 |
| Lee, JT | 1 |
| Lechner, MG | 1 |
| Vaidya, A | 1 |
| Weinmann, M | 1 |
| Beattie, M | 1 |
| Beattie, C | 1 |
| Morrison, ED | 1 |
| Bayasi, G | 1 |
| Lim, CS | 1 |
| Bryant, SM | 1 |
| Wahl, MS | 1 |
| Ahmed, A | 1 |
| Tschetter, PA | 1 |
| Krasowski, MD | 1 |
| Engelman, A | 1 |
| Schier, JG | 1 |
| Hunt, DR | 1 |
| Perala, A | 1 |
| McMartin, KE | 2 |
| Bartels, MJ | 1 |
| Lewis, LS | 1 |
| McGeehin, MA | 1 |
| Flanders, WD | 1 |
| Rietjens, SJ | 1 |
| de Lange, DW | 1 |
| Meulenbelt, J | 1 |
| Frémont, D | 1 |
| Berleur, MP | 1 |
| Zakharov, S | 2 |
| Pelclova, D | 2 |
| Navratil, T | 1 |
| Belacek, J | 1 |
| Komarc, M | 1 |
| Eddleston, M | 2 |
| Thanacoody, RH | 1 |
| Gilfillan, C | 1 |
| Bradberry, SM | 1 |
| Davies, J | 1 |
| Jackson, G | 1 |
| Vale, AJ | 1 |
| Thompson, JP | 1 |
| Thomas, SH | 1 |
| Himmel, ME | 1 |
| Lam, K | 1 |
| Fralick, M | 1 |
| Zamani, N | 2 |
| Collister, D | 1 |
| Duff, G | 1 |
| Palatnick, W | 1 |
| Komenda, P | 1 |
| Tangri, N | 1 |
| Hingwala, J | 1 |
| Rulisek, J | 1 |
| Balik, M | 1 |
| Polak, F | 1 |
| Waldauf, P | 1 |
| Belohlavek, J | 1 |
| Houzé, P | 2 |
| Baud, FJ | 1 |
| Jacobsen, D | 5 |
| Wallace, EA | 1 |
| Green, AS | 1 |
| Berberet, B | 1 |
| Burda, A | 1 |
| Breier, C | 1 |
| Lodolce, AE | 2 |
| Brent, J | 6 |
| Schep, LJ | 1 |
| Slaughter, RJ | 1 |
| Temple, WA | 1 |
| Beasley, DM | 1 |
| González-Santiago, O | 1 |
| Garza-Ocañas, L | 1 |
| Schaeffer, S | 1 |
| Badillo, RB | 1 |
| Akahori, F | 1 |
| Luqman, A | 1 |
| Stanifer, J | 1 |
| Asif Siddiqui, OM | 1 |
| Naseer, A | 1 |
| Wall, BM | 1 |
| Sanaei-Zadeh, H | 1 |
| Shahmohammadi, F | 1 |
| Julsrud, J | 1 |
| Øvrebø, S | 1 |
| Brørs, O | 1 |
| Hann, G | 1 |
| Duncan, D | 1 |
| Sudhir, G | 1 |
| West, P | 1 |
| Sohi, D | 1 |
| Lapatto-Reiniluoto, O | 1 |
| Ikäheimo, R | 1 |
| Barceloux, DG | 2 |
| Bond, GR | 1 |
| Krenzelok, EP | 2 |
| Cooper, H | 1 |
| Vale, JA | 1 |
| Scalley, RD | 1 |
| Ferguson, DR | 1 |
| Piccaro, JC | 1 |
| Smart, ML | 1 |
| Archie, TE | 1 |
| Aakervik, O | 1 |
| Svendsen, J | 1 |
| Essama Mbia, JJ | 1 |
| Guérit, JM | 1 |
| Haufroid, V | 3 |
| Hantson, P | 5 |
| Velez, LI | 3 |
| Kulstad, E | 1 |
| Shepherd, G | 2 |
| Roth, B | 1 |
| Vasavada, N | 1 |
| Williams, C | 1 |
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| Clément de Cléty, S | 1 |
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23 reviews available for fomepizole and Poisoning
| Article | Year |
|---|---|
The three biological gaps and hyperoxaluria in ethylene glycol poisoning: case presentation and review.
Topics: Acidosis; Antidotes; Delayed Diagnosis; Ethylene Glycol; Female; Fomepizole; Humans; Hyperoxaluria; | 2021 |
Treating ethylene glycol poisoning with alcohol dehydrogenase inhibition, but without extracorporeal treatments: a systematic review.
Topics: Acidosis; Acute Kidney Injury; Alcohol Dehydrogenase; Antidotes; Ethanol; Ethylene Glycol; Fomepizol | 2022 |
Extracorporeal treatment for ethylene glycol poisoning: systematic review and recommendations from the EXTRIP workgroup.
Topics: Antidotes; Ethanol; Ethylene Glycol; Fomepizole; Glycolates; Humans; Poisoning; Renal Dialysis | 2023 |
Ethylene glycol or methanol intoxication: which antidote should be used, fomepizole or ethanol?
Topics: Animals; Antidotes; Ethanol; Ethylene Glycol; Fomepizole; Humans; Methanol; Poisoning; Pyrazoles; Re | 2014 |
A Brief Review on Toxic Alcohols: Management Strategies.
Topics: 2-Propanol; Acidosis; Alcoholism; Antidotes; Ethanol; Ethylene Glycol; Fomepizole; Humans; Iran; Met | 2016 |
Expert opinion: fomepizole may ameliorate the need for hemodialysis in methanol poisoning.
Topics: Acidosis; Antidotes; Bicarbonates; Drug Therapy, Combination; Fomepizole; Humans; Methanol; Poisonin | 2008 |
Fomepizole for ethylene glycol and methanol poisoning.
Topics: Acidosis; Adult; Antidotes; Blood Chemical Analysis; Ethylene Glycol; Fomepizole; Humans; Male; Meth | 2009 |
Diethylene glycol poisoning.
Topics: Acidosis; Animals; Antidotes; Drug Contamination; Environmental Exposure; Ethanol; Ethylene Glycols; | 2009 |
Poison control therapy.
Topics: Anesthetics, Local; Antidotes; Antivenins; Calcium Channel Blockers; Child, Preschool; Cyanides; Eme | 2009 |
[Surrogate alcohol poisonings].
Topics: Acidosis; Antidotes; Ethylene Glycol; Finland; Fomepizole; Humans; Methanol; Poisoning; Pyrazoles; R | 2012 |
American Academy of Clinical Toxicology practice guidelines on the treatment of methanol poisoning.
Topics: Ethanol; Fomepizole; Formates; Humans; Leucovorin; Methanol; Poisoning; Practice Guidelines as Topic | 2002 |
Treatment of ethylene glycol poisoning.
Topics: Acidosis; Acute Kidney Injury; Adult; Antidotes; Ethylene Glycol; Fomepizole; Humans; Male; Osmolar | 2002 |
Fomepizole as a therapeutic strategy in paediatric methanol poisoning. A case report and review of the literature.
Topics: Antidotes; Child, Preschool; Drug Therapy, Combination; Fomepizole; Humans; Leucovorin; Male; Methan | 2005 |
New developments in antidotes.
Topics: Animals; Antidotes; Antivenins; Crotalid Venoms; Emergency Treatment; Fomepizole; Glucagon; Humans; | 2005 |
Update on antidotes for pediatric poisoning.
Topics: Acetaminophen; Acetylcysteine; Administration, Oral; Adolescent; Antidotes; Antivenins; Child; Child | 2006 |
[Acute methanol intoxication: physiopathology, prognosis and treatment].
Topics: Acidosis; Acute Disease; Antidotes; Central Nervous System; Fomepizole; Formaldehyde; Humans; Liver; | 2006 |
Ethylene glycol poisoning: current diagnostic and management issues.
Topics: Antidotes; Emergencies; Ethanol; Ethylene Glycol; Fomepizole; Humans; Poisoning; Pyrazoles | 2007 |
Methanol toxicity. Agency for Toxic Substances and Disease Registry.
Topics: Acute Disease; Aged; Chronic Disease; Clinical Protocols; Environmental Exposure; Ethanol; Family Pr | 1993 |
Novel therapies for ethylene glycol intoxication.
Topics: Antidotes; Child; Decontamination; Ethylene Glycol; Fomepizole; Humans; Poisoning; Pyrazoles; Renal | 1999 |
Current management of ethylene glycol poisoning.
Topics: Antidotes; Ethanol; Ethylene Glycol; Fomepizole; Half-Life; Humans; Intestinal Absorption; Poisoning | 2001 |
[Biochemical and clinical aspects of the poisoning with ethylene glycol].
Topics: Antidotes; Chelating Agents; Ethylene Glycols; Fomepizole; Humans; Poisoning; Pyrazoles | 1995 |
Role of fomepizole in the management of ethylene glycol toxicity.
Topics: Alcohol Dehydrogenase; Antidotes; Clinical Trials as Topic; Ethanol; Ethylene Glycol; Fomepizole; Hu | 2002 |
Fomepizole as an antidote for ethylene glycol poisoning.
Topics: Acid-Base Imbalance; Antidotes; Clinical Trials as Topic; Ethylene Glycol; Fomepizole; Humans; Kidne | 2002 |
4 trials available for fomepizole and Poisoning
| Article | Year |
|---|---|
Plasma and tissue determination of 4-methylpyrazole for pharmacokinetic analysis in acute adult and pediatric methanol/ethylene glycol poisoning.
Topics: Administration, Oral; Adult; Antidotes; Chromatography, Gas; Dose-Response Relationship, Drug; Ethyl | 2004 |
Glycolate kinetics and hemodialysis clearance in ethylene glycol poisoning. META Study Group.
Topics: Adult; Aged; Antidotes; Chromatography, Gas; Ethylene Glycol; Female; Fomepizole; Glycolates; Half-L | 1998 |
Fomepizole for the treatment of ethylene glycol poisoning. Methylpyrazole for Toxic Alcohols Study Group.
Topics: Adult; Aged; Antidotes; Ethylene Glycol; Female; Fomepizole; Glycolates; Humans; Keratolytic Agents; | 1999 |
Fomepizole for the treatment of methanol poisoning.
Topics: Acidosis; Adolescent; Adult; Alcohol Dehydrogenase; Antidotes; Enzyme Inhibitors; Female; Fomepizole | 2001 |
57 other studies available for fomepizole and Poisoning
| Article | Year |
|---|---|
Symptomatic Diethylene Glycol Ingestion Successfully Treated with Fomepizole Monotherapy.
Topics: Acidosis; Adult; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Antidotes; Eating; Ethylene Glycol; | 2022 |
Mass Poisoning From Ethylene Glycol at a U.S. Military Base.
Topics: Acidosis; Ethylene Glycol; Fomepizole; Humans; Military Facilities; Poisoning; Renal Dialysis | 2023 |
[Simplified laboratory analysis of ethylene glycol allows improved management of poisoning cases].
Topics: Antidotes; Ethanol; Ethylene Glycol; Fomepizole; Humans; Poisoning; Pyrazoles | 2020 |
[Antifreeze poisoning : The case of a patient with repeated ethylene glycol poisoning].
Topics: Adult; Antidotes; Blood Chemical Analysis; Ethanol; Ethylene Glycol; Fomepizole; Humans; Male; Poiso | 2019 |
Fill in the Gaps: An Unresponsive 55-Year-Old Man.
Topics: Acid-Base Equilibrium; Antidotes; Fomepizole; Humans; Male; Methanol; Middle Aged; Poisoning | 2018 |
Bridging the Gap.
Topics: Acid-Base Equilibrium; Adult; Blood Chemical Analysis; Ethylene Glycol; Fomepizole; Humans; Male; Os | 2019 |
Methanol Toxicity From Occupational Exposure: A Case Report.
Topics: Adult; Diagnosis, Differential; Folic Acid; Fomepizole; Humans; Inhalation Exposure; Male; Methanol; | 2019 |
Management of unintentional methanol ingestions - kids aren't little adults?
Topics: Accidents, Home; Adolescent; Adult; Aged; Antidotes; Child; Child, Preschool; Female; Fomepizole; Hu | 2013 |
Massive ethylene glycol poisoning triggers osmotic demyelination syndrome.
Topics: Antidotes; Ethylene Glycol; Female; Fomepizole; Humans; Middle Aged; Myelinolysis, Central Pontine; | 2014 |
Characterizing concentrations of diethylene glycol and suspected metabolites in human serum, urine, and cerebrospinal fluid samples from the Panama DEG mass poisoning.
Topics: Acetates; Biomarkers; Case-Control Studies; Centers for Disease Control and Prevention, U.S.; Ethyle | 2013 |
Loading dose of fomepizole is safe in children with presumed toxic alcohol exposure - a case series.
Topics: Alcohol Dehydrogenase; Alcohols; Antidotes; Child; Child, Preschool; Dose-Response Relationship, Dru | 2014 |
Fomepizole versus ethanol in the treatment of acute methanol poisoning: Comparison of clinical effectiveness in a mass poisoning outbreak.
Topics: Administration, Intravenous; Adolescent; Adult; Aged; Antidotes; Chi-Square Distribution; Cross-Sect | 2015 |
Management of poisoning with ethylene glycol and methanol in the UK: a prospective study conducted by the National Poisons Information Service (NPIS).
Topics: Adult; Antidotes; Disease Management; Ethanol; Ethylene Glycol; Fomepizole; Hospitalization; Humans; | 2016 |
Hemodialysis in a Healthy Patient--A Case of an Erroneous Laboratory Result: A Teachable Moment.
Topics: Acidosis; Alcoholism; Antidotes; Diagnostic Errors; Female; Fomepizole; Humans; Medical Errors; Meth | 2016 |
A Methanol Intoxication Outbreak From Recreational Ingestion of Fracking Fluid.
Topics: Acid-Base Equilibrium; Acidosis; Adult; Antidotes; Disease Outbreaks; Eating; Fomepizole; Humans; Hy | 2017 |
Cost-effectiveness of hospital treatment and outcomes of acute methanol poisoning during the Czech Republic mass poisoning outbreak.
Topics: Adult; Alcoholism; Antidotes; Cost-Benefit Analysis; Cross-Sectional Studies; Czech Republic; Diseas | 2017 |
Oral fomepizole administration to treat ethylene glycol and methanol poisonings: advantages and limitations.
Topics: Administration, Oral; Adult; Antidotes; Ethylene Glycol; Female; Fomepizole; Humans; Injections, Int | 2008 |
Methanol toxicity secondary to inhalant abuse in adult men.
Topics: Acidosis; Adult; Antidotes; Ethanol; Ethnicity; Fomepizole; Hispanic or Latino; Humans; Indians, Nor | 2009 |
Discontinuation of 5% alcohol in 5% dextrose injection: implications for antidote stocking.
Topics: Alcohols; Antidotes; Drug Therapy, Combination; Ethylene Glycol; Fomepizole; Glucose; Humans; Illino | 2008 |
Fomepizole for toxic alcohol poisoning.
Topics: Antidotes; Drug Interactions; Ethanol; Ethylene Glycol; Fomepizole; Humans; Methanol; Poisoning; Pyr | 2009 |
[Application in veterinary and human clinical toxicology].
Topics: Acetaminophen; Aflatoxins; Animals; Biphenyl Compounds; Cat Diseases; Cats; Chickens; Ethylene Glyco | 2009 |
Calcium oxalate monohydrate crystals: a clue to ethylene glycol poisoning.
Topics: Antidotes; Calcium Oxalate; Crystallization; Ethylene Glycol; Fomepizole; Humans; Male; Middle Aged; | 2011 |
Can fomepizole be substituted by abacavir in the treatment of methanol poisoning?
Topics: Antidotes; Dideoxynucleosides; Drug Substitution; Fomepizole; Humans; Methanol; Poisoning; Pyrazoles | 2011 |
Studies on ethylene glycol poisoning: one patient - 154 admissions.
Topics: Adult; Antidotes; Dissociative Disorders; Ethylene Glycol; Female; Fomepizole; Glycolates; Half-Life | 2011 |
Antifreeze on a freezing morning: ethylene glycol poisoning in a 2-year-old.
Topics: Antidotes; Child, Preschool; Ethylene Glycol; Fomepizole; Humans; Male; Poisoning; Pyrazoles | 2012 |
[Severe ethylene glycol poisoning treated wtih fomepizole (4-methylpyrazole)].
Topics: Adult; Antidotes; Ethylene Glycol; Female; Fomepizole; Humans; Infusions, Intravenous; Male; Middle | 2002 |
Fomepizole therapy for reversal of visual impairment after methanol poisoning: a case documented by visual evoked potentials investigation.
Topics: Alcohol Dehydrogenase; Antidotes; Electroretinography; Evoked Potentials, Visual; Fomepizole; Humans | 2002 |
Inhalational methanol toxicity in pregnancy treated twice with fomepizole.
Topics: Administration, Inhalation; Adult; Antidotes; Diagnosis, Differential; Emergency Treatment; Female; | 2003 |
Ethylene glycol intoxication: case report and pharmacokinetic perspectives.
Topics: Adult; Antidotes; Ethylene Glycol; Fomepizole; Humans; Male; Poisoning; Pyrazoles | 2003 |
Fomepizole alone for severe infant ethylene glycol poisoning.
Topics: Accidents, Home; Antidotes; Dose-Response Relationship, Drug; Drug Administration Schedule; Emergenc | 2004 |
Aniline and methanol toxicity after shoe dye ingestion.
Topics: Adult; Aniline Compounds; Antidotes; Coloring Agents; Emergency Medical Services; Erythrocyte Transf | 2004 |
Outcomes following abuse of methanol-containing carburetor cleaners.
Topics: Acidosis; Adolescent; Adult; Antidotes; Ethanol; Female; Fluid Therapy; Fomepizole; Humans; Inhalati | 2004 |
Methanol outbreak in Norway 2002-2004: epidemiology, clinical features and prognostic signs.
Topics: Adult; Aged; Antidotes; Carbon Dioxide; Disease Outbreaks; Ethanol; Female; Fomepizole; Humans; Male | 2005 |
Unavailability of 10% alcohol in 5% dextrose injection.
Topics: Alcohols; Antidotes; Fomepizole; Glucose; Humans; Injections; Poison Control Centers; Poisoning; Pyr | 2005 |
Hyperosmolality: another indication for hemodialysis following acute ethylene glycol poisoning.
Topics: Acid-Base Imbalance; Antidotes; Ethylene Glycol; Female; Fomepizole; Humans; Middle Aged; Osmolar Co | 2006 |
Prehospital diagnosis of massive ethylene glycol poisoning and use of an early antidote.
Topics: Adult; Antidotes; Early Diagnosis; Emergency Medical Services; Ethylene Glycol; Fomepizole; Humans; | 2006 |
A case of mixed intoxication with isopropyl alcohol and propanol-1 after ingestion of a topical antiseptic solution.
Topics: 1-Propanol; 2-Propanol; Adult; Anti-Infective Agents, Local; Antidotes; Drug Combinations; Female; F | 2007 |
The management of severe toxic alcohol ingestions at a tertiary care center after the introduction of fomepizole.
Topics: Adult; Alcohol Dehydrogenase; Antidotes; Databases, Factual; Ethanol; Ethylene Glycol; Female; Fomep | 2007 |
Ethylene glycol ingestion treated only with fomepizole.
Topics: Acid-Base Imbalance; Adult; Antidotes; Ethylene Glycol; Fomepizole; Humans; Injections, Intravenous; | 2007 |
Methanol poisoning: the duality between 'fast and cheap' and 'slow and expensive'.
Topics: Adult; Antidotes; Belgium; Ethanol; Female; Fomepizole; Hospital Costs; Humans; Inactivation, Metabo | 2008 |
Efficacy of 4-methylpyrazole in ethylene glycol poisoning: clinical and toxicokinetic aspects.
Topics: Adult; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Male; Poisoning; Pyrazoles | 1994 |
Safety and efficacy of 4-methylpyrazole for treatment of suspected or confirmed ethylene glycol intoxication in dogs: 107 cases (1983-1995).
Topics: Acid-Base Equilibrium; Alcohol Dehydrogenase; Animals; Dog Diseases; Dogs; Enzyme Inhibitors; Ethyle | 1996 |
High-performance liquid chromatographic determination of 4-methylpyrazole in plasma and in dialysate.
Topics: Alcohol Dehydrogenase; Chromatography, High Pressure Liquid; Dialysis Solutions; Ethylene Glycol; Et | 1997 |
Treatment of methanol poisoning with intravenous 4-methylpyrazole.
Topics: Adult; Alcohol Dehydrogenase; Enzyme Inhibitors; Fomepizole; Humans; Infusions, Intravenous; Male; M | 1997 |
Ethylene glycol antidote cleared for marketing.
Topics: Antidotes; Ethylene Glycol; Fomepizole; Humans; Inactivation, Metabolic; Poisoning; Pyrazoles | 1998 |
Ethylene glycol poisoning treated by intravenous 4-methylpyrazole.
Topics: Acid-Base Equilibrium; Adult; Antidotes; Biotransformation; Creatinine; Ethylene Glycol; Female; Fom | 1998 |
Ethylene glycol poisoning in a child treated with 4-methylpyrazole.
Topics: Antidotes; Child, Preschool; Chromatography, High Pressure Liquid; Drug Administration Schedule; Eth | 1998 |
New treatment for ethylene glycol poisoning.
Topics: Antidotes; Ethanol; Ethylene Glycol; Fomepizole; Humans; Poisoning; Pyrazoles | 1999 |
Two cases of acute methanol poisoning partially treated by oral 4-methylpyrazole.
Topics: Administration, Oral; Adolescent; Antidotes; Ethanol; Female; Fomepizole; Humans; Male; Methanol; Mi | 1999 |
American Academy of Clinical Toxicology Practice Guidelines on the Treatment of Ethylene Glycol Poisoning. Ad Hoc Committee.
Topics: Antidotes; Ethylene Glycol; Fomepizole; Humans; Poisoning; Pyrazoles | 1999 |
Childhood diethylene glycol poisoning treated with alcohol dehydrogenase inhibitor fomepizole and hemodialysis.
Topics: Antidotes; Ethylene Glycols; Female; Fomepizole; Humans; Infant; Poisoning; Pyrazoles; Renal Dialysi | 2000 |
Delayed toxicity in acute ethanol-methanol copoisoning in a chronic alcohol abuser: usefulness of continuous 4-methylpyrazole (fomepizole) infusion.
Topics: Antidotes; Ethanol; Fomepizole; Humans; Methanol; Poisoning; Pyrazoles | 2000 |
Fomepizole treatment of ethylene glycol poisoning in an infant.
Topics: Antidotes; Ethylene Glycol; Fomepizole; Humans; Infant; Male; Poisoning; Pyrazoles; Renal Dialysis; | 2000 |
Fomepizole in the treatment of poisoning.
Topics: Adult; Alcohol Dehydrogenase; Antidotes; Child; Drug Costs; Ethylene Glycol; Fomepizole; Humans; Met | 2001 |
Severe ethylene glycol ingestion treated without hemodialysis.
Topics: Adolescent; Antidotes; Ethanol; Ethylene Glycol; Female; Fomepizole; Humans; Infusions, Intravenous; | 2001 |
Childhood methanol ingestion treated with fomepizole and hemodialysis.
Topics: Adult; Antidotes; Child, Preschool; Fomepizole; Humans; Male; Methanol; Poisoning; Pyrazoles; Renal | 2001 |
[Do antidotes have a future? The example of 4-methylpyrazole and hydroxocobalamin].
Topics: Antidotes; Binding, Competitive; Cyanides; Ethylene Glycols; Fomepizole; Humans; Hydroxocobalamin; I | 1992 |