fomepizole has been researched along with Liver Diseases, Alcoholic in 6 studies
Fomepizole: A pyrazole and competitive inhibitor of ALCOHOL DEHYDROGENASE that is used for the treatment of poisoning by ETHYLENE GLYCOL or METHANOL.
fomepizole : A member of the class of pyrazoles that is 1H-pyrazole substituted by a methyl group at position 4.
Liver Diseases, Alcoholic: Liver diseases associated with ALCOHOLISM. It usually refers to the coexistence of two or more subentities, i.e., ALCOHOLIC FATTY LIVER; ALCOHOLIC HEPATITIS; and ALCOHOLIC CIRRHOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Malondialdehyde (MDA) levels were determined in order to assess lipid peroxidation, and caspase-3 activity was determined by immunostaining of liver tissues to evaluate apoptosis." | 1.36 | Effect of lycopene on caspase-3 enzyme activation in liver of methanol-intoxicated rats: comparison with fomepizole. ( Aksoy, N; Atessahin, A; Baba, F; Koksal, M; Kurcer, MA; Kurcer, Z; Ocak, AR; Sahna, E, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kurcer, MA | 1 |
| Kurcer, Z | 1 |
| Koksal, M | 1 |
| Baba, F | 1 |
| Ocak, AR | 1 |
| Aksoy, N | 1 |
| Atessahin, A | 1 |
| Sahna, E | 1 |
| Dudka, J | 1 |
| Burdan, F | 1 |
| Madej, B | 1 |
| Tokarska, E | 1 |
| Klepacz, R | 1 |
| Korobowicz, E | 1 |
| Young, A | 1 |
| Berti-Mattera, L | 1 |
| Romani, A | 1 |
| Seth, D | 1 |
| Hogg, PJ | 1 |
| Gorrell, MD | 1 |
| McCaughan, GW | 1 |
| Haber, PS | 1 |
| Bailey, SM | 1 |
| Cunningham, CC | 1 |
| Salaspuro, M | 1 |
6 other studies available for fomepizole and Liver Diseases, Alcoholic
| Article | Year |
|---|---|
Effect of lycopene on caspase-3 enzyme activation in liver of methanol-intoxicated rats: comparison with fomepizole.
Topics: Animals; Carotenoids; Caspase 3; Disease Models, Animal; Enzyme Activation; Female; Fomepizole; Huma | 2010 |
[Human erythrocyte lactate dehydrogenase activity changes in the presence of some alcohol dehydrogenase inhibitors].
Topics: Adult; Alcohol Dehydrogenase; Cimetidine; Edetic Acid; Enzyme Inhibitors; Erythrocytes; Ethanol; Fem | 2004 |
Effect of repeated doses of ethanol on hepatic Mg2+ homeostasis and mobilization.
Topics: Adrenergic Agonists; Animals; Dose-Response Relationship, Drug; Ethanol; Fomepizole; GTP-Binding Pro | 2007 |
Direct effects of alcohol on hepatic fibrinolytic balance: implications for alcoholic liver disease.
Topics: Animals; Annexin A2; Antidotes; Biopsy; Cell Line; Central Nervous System Depressants; Disease Model | 2008 |
Acute and chronic ethanol increases reactive oxygen species generation and decreases viability in fresh, isolated rat hepatocytes.
Topics: Alcohol Dehydrogenase; Animals; Cell Survival; Cyanamide; Enzyme Inhibitors; Ethanol; Fomepizole; Ki | 1998 |
Inhibitors of alcohol metabolism.
Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Drug Interactions; Ethanol; Fomepizole; Hum | 1985 |