fomepizole has been researched along with Kidney Diseases in 5 studies
Fomepizole: A pyrazole and competitive inhibitor of ALCOHOL DEHYDROGENASE that is used for the treatment of poisoning by ETHYLENE GLYCOL or METHANOL.
fomepizole : A member of the class of pyrazoles that is 1H-pyrazole substituted by a methyl group at position 4.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ethylene glycol poisoning causes metabolic acidosis and renal failure and may cause death." | 9.09 | Fomepizole for the treatment of ethylene glycol poisoning. Methylpyrazole for Toxic Alcohols Study Group. ( Brent, J; Burkhart, KK; Donovan, JW; Kulig, K; McMartin, K; Phillips, S; Wells, M, 1999) |
| "Diethylene glycol (DEG) is a clear, colorless, practically odorless, viscous, hygroscopic liquid with a sweetish taste." | 6.45 | Diethylene glycol poisoning. ( Beasley, DM; Schep, LJ; Slaughter, RJ; Temple, WA, 2009) |
| "Ethylene glycol poisoning causes metabolic acidosis and renal failure and may cause death." | 5.09 | Fomepizole for the treatment of ethylene glycol poisoning. Methylpyrazole for Toxic Alcohols Study Group. ( Brent, J; Burkhart, KK; Donovan, JW; Kulig, K; McMartin, K; Phillips, S; Wells, M, 1999) |
| "Diethylene glycol (DEG) is a clear, colorless, practically odorless, viscous, hygroscopic liquid with a sweetish taste." | 2.45 | Diethylene glycol poisoning. ( Beasley, DM; Schep, LJ; Slaughter, RJ; Temple, WA, 2009) |
| "Treatment with fomepizole blocked the formation of HEAA and DGA and the kidney toxicity." | 1.37 | Role of tissue metabolite accumulation in the renal toxicity of diethylene glycol. ( Bartels, M; Besenhofer, LM; Filary, MJ; Latimer, B; McLaren, MC; McMartin, KE; Perala, AW, 2011) |
| "Treatment for ethylene glycol poisoning typically includes basic supportive care, alcohol dehydrogenase inhibition, and hemodialysis." | 1.34 | Ethylene glycol ingestion treated only with fomepizole. ( Keyes, DC; Lee, YC; Shepherd, G; Velez, LI, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sommerfeld-Klatta, K | 1 |
| Przystanowicz, J | 1 |
| Kowalówka-Zawieja, J | 1 |
| Zielińska-Psuja, B | 1 |
| Schep, LJ | 1 |
| Slaughter, RJ | 1 |
| Temple, WA | 1 |
| Beasley, DM | 1 |
| Besenhofer, LM | 1 |
| McLaren, MC | 1 |
| Latimer, B | 1 |
| Bartels, M | 1 |
| Filary, MJ | 1 |
| Perala, AW | 1 |
| McMartin, KE | 1 |
| Velez, LI | 1 |
| Shepherd, G | 1 |
| Lee, YC | 1 |
| Keyes, DC | 1 |
| Brent, J | 1 |
| McMartin, K | 1 |
| Phillips, S | 1 |
| Burkhart, KK | 1 |
| Donovan, JW | 1 |
| Wells, M | 1 |
| Kulig, K | 1 |
1 review available for fomepizole and Kidney Diseases
| Article | Year |
|---|---|
Diethylene glycol poisoning.
Topics: Acidosis; Animals; Antidotes; Drug Contamination; Environmental Exposure; Ethanol; Ethylene Glycols; | 2009 |
1 trial available for fomepizole and Kidney Diseases
| Article | Year |
|---|---|
Fomepizole for the treatment of ethylene glycol poisoning. Methylpyrazole for Toxic Alcohols Study Group.
Topics: Adult; Aged; Antidotes; Ethylene Glycol; Female; Fomepizole; Glycolates; Humans; Keratolytic Agents; | 1999 |
3 other studies available for fomepizole and Kidney Diseases
| Article | Year |
|---|---|
Effect of repeated administration of 4-methylpyrazole on renal function and lipid peroxidation products in rat kidney after ethylene glycol poisoning.
Topics: Animals; Antidotes; Biotransformation; Cytochrome P-450 CYP2E1; Dose-Response Relationship, Drug; Dr | 2017 |
Role of tissue metabolite accumulation in the renal toxicity of diethylene glycol.
Topics: Acetates; Acidosis; Animals; Antidotes; Ethylene Glycols; Fomepizole; Kidney; Kidney Diseases; Male; | 2011 |
Ethylene glycol ingestion treated only with fomepizole.
Topics: Acid-Base Imbalance; Adult; Antidotes; Ethylene Glycol; Fomepizole; Humans; Injections, Intravenous; | 2007 |