fomepizole has been researched along with Disease Exacerbation in 4 studies
Fomepizole: A pyrazole and competitive inhibitor of ALCOHOL DEHYDROGENASE that is used for the treatment of poisoning by ETHYLENE GLYCOL or METHANOL.
fomepizole : A member of the class of pyrazoles that is 1H-pyrazole substituted by a methyl group at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present an unusual case of a coingestion of ethanol and 150-250 mL of pure 2BE, which resulted in rapid obtundation, severe airway edema, hypotension, and prolonged acidosis despite the coingestion of ethanol and the administration of a loading dose of fomepizole." | 7.76 | Fomepizole fails to prevent progression of acidosis in 2-butoxyethanol and ethanol coingestion. ( Dewitt, CR; Holmes, DT; Hung, T; Martz, W; Schreiber, W, 2010) |
| " In many cases of pediatric ethylene glycol poisoning treated with fomepizole, hemodialysis may not be necessary despite high concentrations and the presence of metabolic acidosis." | 4.86 | Fomepizole for the treatment of pediatric ethylene and diethylene glycol, butoxyethanol, and methanol poisonings. ( Brent, J, 2010) |
| "We present an unusual case of a coingestion of ethanol and 150-250 mL of pure 2BE, which resulted in rapid obtundation, severe airway edema, hypotension, and prolonged acidosis despite the coingestion of ethanol and the administration of a loading dose of fomepizole." | 3.76 | Fomepizole fails to prevent progression of acidosis in 2-butoxyethanol and ethanol coingestion. ( Dewitt, CR; Holmes, DT; Hung, T; Martz, W; Schreiber, W, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hung, T | 1 |
| Dewitt, CR | 1 |
| Martz, W | 1 |
| Schreiber, W | 1 |
| Holmes, DT | 1 |
| Brent, J | 1 |
| Caravati, EM | 1 |
| Heileson, HL | 1 |
| Jones, M | 1 |
| Seth, D | 1 |
| Hogg, PJ | 1 |
| Gorrell, MD | 1 |
| McCaughan, GW | 1 |
| Haber, PS | 1 |
1 review available for fomepizole and Disease Exacerbation
| Article | Year |
|---|---|
Fomepizole for the treatment of pediatric ethylene and diethylene glycol, butoxyethanol, and methanol poisonings.
Topics: Acidosis; Adult; Alcoholism; Antidotes; Bicarbonates; Child; Disease Progression; Ethanol; Ethylene | 2010 |
3 other studies available for fomepizole and Disease Exacerbation
| Article | Year |
|---|---|
Fomepizole fails to prevent progression of acidosis in 2-butoxyethanol and ethanol coingestion.
Topics: Acidosis; Alcohol Dehydrogenase; Antidotes; Disease Progression; Ethanol; Ethylene Glycols; Fomepizo | 2010 |
Treatment of severe pediatric ethylene glycol intoxication without hemodialysis.
Topics: Acidosis; Adolescent; Antidotes; Bicarbonates; Child; Creatine; Disease Progression; Ethylene Glycol | 2004 |
Direct effects of alcohol on hepatic fibrinolytic balance: implications for alcoholic liver disease.
Topics: Animals; Annexin A2; Antidotes; Biopsy; Cell Line; Central Nervous System Depressants; Disease Model | 2008 |