fomepizole has been researched along with Coma in 2 studies
Fomepizole: A pyrazole and competitive inhibitor of ALCOHOL DEHYDROGENASE that is used for the treatment of poisoning by ETHYLENE GLYCOL or METHANOL.
fomepizole : A member of the class of pyrazoles that is 1H-pyrazole substituted by a methyl group at position 4.
Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The case of a 43-year-old man who ingested 30 mL of a homemade 1,4-butanediol solution and who developed general seizures and coma has been reported here." | 3.71 | Treatment of a 1,4-butanediol poisoning with fomepizole. ( Baud, FJ; Fompeydie, D; Garnier, R; Mégarbane, B, 2002) |
| "The fomepizole treatment protocol (10 mg/kg by i." | 1.30 | Fomepizole (4-methylpyrazole) in fatal methanol poisoning with early CT scan cerebral lesions. ( Bonmarchand, G; Callonnec, F; Droy, JM; Girault, C; Leroy, J; Moritz, F; Tamion, F, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Girault, C | 1 |
| Tamion, F | 1 |
| Moritz, F | 1 |
| Callonnec, F | 1 |
| Droy, JM | 1 |
| Bonmarchand, G | 1 |
| Leroy, J | 1 |
| Mégarbane, B | 1 |
| Fompeydie, D | 1 |
| Garnier, R | 1 |
| Baud, FJ | 1 |
2 other studies available for fomepizole and Coma
| Article | Year |
|---|---|
Fomepizole (4-methylpyrazole) in fatal methanol poisoning with early CT scan cerebral lesions.
Topics: Acidosis; Adult; Alcohol Dehydrogenase; Antidotes; Brain; Coma; Dialysis; Enzyme Inhibitors; Fatal O | 1999 |
Treatment of a 1,4-butanediol poisoning with fomepizole.
Topics: Adult; Antidotes; Butylene Glycols; Coma; Fomepizole; Humans; Hydroxybutyrates; Infusions, Intraveno | 2002 |