fomepizole has been researched along with Alcohol Drinking in 14 studies
Fomepizole: A pyrazole and competitive inhibitor of ALCOHOL DEHYDROGENASE that is used for the treatment of poisoning by ETHYLENE GLYCOL or METHANOL.
fomepizole : A member of the class of pyrazoles that is 1H-pyrazole substituted by a methyl group at position 4.
Alcohol Drinking: Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The results showed that EtOH and acetaldehyde decreased ChAT expression at 40 and 240 min after EtOH dosing in the brain." | 1.34 | Ethanol and acetaldehyde: in vivo quantitation and effects on cholinergic function in rat brain. ( Ameno, K; Ijiri, I; Ikuo, U; Jamal, M; Kumihashi, M; Wang, W, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (42.86) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Haseba, T | 1 |
| Okuda, T | 1 |
| Maruyama, M | 1 |
| Akimoto, T | 1 |
| Duester, G | 1 |
| Ohno, Y | 1 |
| Pavshintsev, VV | 1 |
| Mitkin, NA | 1 |
| Frolova, OY | 1 |
| Kushnir, EA | 1 |
| Averina, OA | 1 |
| Lovat, ML | 1 |
| Ng, PCY | 1 |
| Long, BJ | 1 |
| Davis, WT | 1 |
| Sessions, DJ | 1 |
| Koyfman, A | 1 |
| Lang, CH | 1 |
| Quintanilla, ME | 1 |
| Tampier, L | 1 |
| Jamal, M | 1 |
| Ameno, K | 1 |
| Ikuo, U | 1 |
| Kumihashi, M | 1 |
| Wang, W | 1 |
| Ijiri, I | 1 |
| Kupari, M | 1 |
| Lindros, K | 1 |
| Hillbom, M | 1 |
| Heikkilä, J | 1 |
| Ylikahri, R | 1 |
| Gentry, RT | 1 |
| Rappaport, MS | 1 |
| Dole, VP | 1 |
| Waller, MB | 1 |
| McBride, WJ | 1 |
| Lumeng, L | 1 |
| Li, TK | 1 |
| Carr, G | 1 |
| Brown, ZW | 1 |
| Rockman, GE | 1 |
| Amit, Z | 2 |
| Sinclair, JD | 1 |
| Lindros, KO | 1 |
| Jacobsen, D | 1 |
| Sebastian, CS | 1 |
| Dies, DF | 1 |
| Breau, RL | 1 |
| Spann, EG | 1 |
| Barron, SK | 1 |
| McMartin, KE | 1 |
| Vendemiale, G | 1 |
| Grattagliano, I | 1 |
| Signorile, A | 1 |
| Altomare, E | 1 |
| Spivak, KJ | 1 |
1 review available for fomepizole and Alcohol Drinking
| Article | Year |
|---|---|
Toxic alcohol diagnosis and management: an emergency medicine review.
Topics: 2-Propanol; Alcohol Drinking; Alcohols; Antidotes; Emergency Service, Hospital; Ethanol; Ethylene Gl | 2018 |
1 trial available for fomepizole and Alcohol Drinking
| Article | Year |
|---|---|
Kinetic interactions between 4-methylpyrazole and ethanol in healthy humans.
Topics: Adult; Alcohol Dehydrogenase; Alcohol Drinking; Cross-Over Studies; Dose-Response Relationship, Drug | 1996 |
12 other studies available for fomepizole and Alcohol Drinking
| Article | Year |
|---|---|
Roles of Two Major Alcohol Dehydrogenases, ADH1 (Class I) and ADH3 (Class III), in the Adaptive Enhancement of Alcohol Metabolism Induced by Chronic Alcohol Consumption in Mice.
Topics: Alcohol Dehydrogenase; Alcohol Drinking; Animals; Ethanol; Fomepizole; Genotype; Male; Mice; Mice, I | 2020 |
Individual roles of brain and serum alcohol dehydrogenase isoforms in regulation of alcohol consumption in SPF Wistar rats.
Topics: Alcohol Dehydrogenase; Alcohol Drinking; Animals; Antibodies; Biomarkers; Brain; Dose-Response Relat | 2017 |
Lack of sexual dimorphism on the inhibitory effect of alcohol on muscle protein synthesis in rats under basal conditions and after anabolic stimulation.
Topics: Alcohol Dehydrogenase; Alcohol Drinking; Animals; Central Nervous System Depressants; Enzyme Inhibit | 2018 |
Place conditioning with ethanol in rats bred for high (UChB) and low (UChA) voluntary alcohol drinking.
Topics: Acetaldehyde; Alcohol Drinking; Aldehyde Dehydrogenase; Animals; Breeding; Conditioning, Psychologic | 2011 |
Ethanol and acetaldehyde: in vivo quantitation and effects on cholinergic function in rat brain.
Topics: Acetaldehyde; Alcohol Drinking; Animals; Blotting, Western; Brain; Catalase; Choline O-Acetyltransfe | 2007 |
Cardiovascular effects of acetaldehyde accumulation after ethanol ingestion: their modification by beta-adrenergic blockade and alcohol dehydrogenase inhibition.
Topics: Acetaldehyde; Adult; Alcohol Dehydrogenase; Alcohol Drinking; Alcohol Oxidoreductases; Alcoholic Int | 1983 |
Elevated concentrations of ethanol in plasma do not suppress voluntary ethanol consumption in C57BL mice.
Topics: Alcohol Drinking; Animals; Body Weight; Eating; Ethanol; Fomepizole; Male; Metabolic Clearance Rate; | 1983 |
Effects of intravenous ethanol and of 4-methylpyrazole on alcohol drinking in alcohol-preferring rats.
Topics: Alcohol Drinking; Alcoholism; Animals; Disease Models, Animal; Ethanol; Fomepizole; Humans; Male; Py | 1982 |
Reduction in voluntary ethanol consumption by treatment with alcohol dehydrogenase inhibitors.
Topics: Alcohol Drinking; Alcohol Oxidoreductases; Animals; Fomepizole; Male; Pyrazoles; Rats; Rats, Inbred | 1980 |
Suppression of alcohol drinking with brain aldehyde dehydrogenase inhibition.
Topics: Acetaldehyde; Alcohol Drinking; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Animals; Brain; Cy | 1981 |
Ethanol-induced changes of intracellular thiol compartmentation and protein redox status in the rat liver: effect of tauroursodeoxycholate.
Topics: Acetaldehyde; Alcohol Drinking; Animals; Cell Nucleus; Cyanamide; Cytosol; Ethanol; Fomepizole; Glut | 1998 |
The role of acetaldehyde-metabolizing enzymes in the mediation of ethanol consumption: an investigation using a simulated drinking bout.
Topics: Acetaldehyde; Alcohol Drinking; Aldehyde Dehydrogenase; Animals; Cyanamide; Fomepizole; Male; Pyrazo | 1987 |