fomepizole has been researched along with Alcohol Abuse in 14 studies
Fomepizole: A pyrazole and competitive inhibitor of ALCOHOL DEHYDROGENASE that is used for the treatment of poisoning by ETHYLENE GLYCOL or METHANOL.
fomepizole : A member of the class of pyrazoles that is 1H-pyrazole substituted by a methyl group at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "During an outbreak of mass methanol poisoning in the Czech Republic in 2012-2014, we compared the total hospital costs and one-year medical costs in the patients treated with different antidotes (fomepizole versus ethanol) and modalities of hemodialysis (intermittent hemodialysis, IHD, versus continuous renal replacement therapy, CRRT)." | 7.85 | Cost-effectiveness of hospital treatment and outcomes of acute methanol poisoning during the Czech Republic mass poisoning outbreak. ( Balik, M; Belohlavek, J; Pelclova, D; Polak, F; Rulisek, J; Waldauf, P; Zakharov, S, 2017) |
| " In many cases of pediatric ethylene glycol poisoning treated with fomepizole, hemodialysis may not be necessary despite high concentrations and the presence of metabolic acidosis." | 4.86 | Fomepizole for the treatment of pediatric ethylene and diethylene glycol, butoxyethanol, and methanol poisonings. ( Brent, J, 2010) |
| "During an outbreak of mass methanol poisoning in the Czech Republic in 2012-2014, we compared the total hospital costs and one-year medical costs in the patients treated with different antidotes (fomepizole versus ethanol) and modalities of hemodialysis (intermittent hemodialysis, IHD, versus continuous renal replacement therapy, CRRT)." | 3.85 | Cost-effectiveness of hospital treatment and outcomes of acute methanol poisoning during the Czech Republic mass poisoning outbreak. ( Balik, M; Belohlavek, J; Pelclova, D; Polak, F; Rulisek, J; Waldauf, P; Zakharov, S, 2017) |
| "The information on burden of alcohol abuse in Iran is scarce." | 2.53 | A Brief Review on Toxic Alcohols: Management Strategies. ( Hassanian-Moghaddam, H; Zamani, N, 2016) |
| "Chronic alcohol abuse inhibits alcohol dehydrogenase (ADH) and facilitates nonoxidative metabolism of ethanol to fatty acid ethyl esters (FAEEs) in the pancreas frequently damaged during chronic ethanol abuse." | 1.40 | Alcohol oxidizing enzymes and ethanol-induced cytotoxicity in rat pancreatic acinar AR42J cells. ( Ansari, GA; Bhopale, KK; Falzon, M; Kaphalia, BS, 2014) |
| " She received fomepizole at dosing corrected for hemodialysis(HD), and bicarbonate via multiple boluses and continuous infusion." | 1.35 | Head CT in patient with metabolic acidosis. ( Babu, KM; Boyer, EW; Rosenbaum, CD, 2008) |
| "Pyrazole treatment produced an identical 3- to 4-fold increase in content and catalytic activity of P450 2E1 in the two lines." | 1.28 | The content and activity of cytochrome P450 2E1 in liver microsomes from alcohol-preferring and non-preferring rats. ( Cederbaum, AI; Winters, DK, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (21.43) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beauchamp, GA | 1 |
| Valento, M | 1 |
| Kim, J | 1 |
| Kettritz, R | 1 |
| Ritter, T | 1 |
| Rudolph, B | 1 |
| Luft, FC | 1 |
| Bhopale, KK | 1 |
| Falzon, M | 1 |
| Ansari, GA | 1 |
| Kaphalia, BS | 1 |
| Meng, X | 1 |
| Paul, S | 1 |
| Federman, DJ | 1 |
| Himmel, ME | 1 |
| Lam, K | 1 |
| Fralick, M | 1 |
| Hassanian-Moghaddam, H | 1 |
| Zamani, N | 1 |
| Rulisek, J | 1 |
| Balik, M | 1 |
| Polak, F | 1 |
| Waldauf, P | 1 |
| Pelclova, D | 1 |
| Belohlavek, J | 1 |
| Zakharov, S | 1 |
| Babu, KM | 1 |
| Rosenbaum, CD | 1 |
| Boyer, EW | 1 |
| Brent, J | 1 |
| Tuohy, KA | 1 |
| Nicholson, WJ | 1 |
| Schiffman, F | 1 |
| Van Thiel, DH | 1 |
| Waller, MB | 1 |
| McBride, WJ | 1 |
| Lumeng, L | 1 |
| Li, TK | 1 |
| Lindros, KO | 1 |
| Stowell, A | 1 |
| Pikkarainen, P | 1 |
| Salaspuro, M | 1 |
| Winters, DK | 1 |
| Cederbaum, AI | 1 |
3 reviews available for fomepizole and Alcohol Abuse
| Article | Year |
|---|---|
Toxic alcohol ingestion: prompt recognition and management in the emergency department [digest].
Topics: 2-Propanol; Alcoholism; Antidotes; Diagnosis, Differential; Emergency Service, Hospital; Ethanol; Et | 2016 |
A Brief Review on Toxic Alcohols: Management Strategies.
Topics: 2-Propanol; Acidosis; Alcoholism; Antidotes; Ethanol; Ethylene Glycol; Fomepizole; Humans; Iran; Met | 2016 |
Fomepizole for the treatment of pediatric ethylene and diethylene glycol, butoxyethanol, and methanol poisonings.
Topics: Acidosis; Adult; Alcoholism; Antidotes; Bicarbonates; Child; Disease Progression; Ethanol; Ethylene | 2010 |
11 other studies available for fomepizole and Alcohol Abuse
| Article | Year |
|---|---|
The Case | Acid-base diagnoses in the 21st century.
Topics: Acidosis; Acute Kidney Injury; Alcoholic Intoxication; Alcoholism; Antidotes; Creatinine; Ethylene G | 2017 |
Alcohol oxidizing enzymes and ethanol-induced cytotoxicity in rat pancreatic acinar AR42J cells.
Topics: Acinar Cells; Alcohol Dehydrogenase; Alcoholism; Animals; Apoptosis; Ethanol; Fatty Acids; Fomepizol | 2014 |
Metabolic acidosis in a patient with isopropyl alcohol intoxication: a case report.
Topics: 2-Propanol; Acidosis; Alcoholism; Antidotes; Female; Fomepizole; Humans; Middle Aged; Pyrazoles | 2015 |
Hemodialysis in a Healthy Patient--A Case of an Erroneous Laboratory Result: A Teachable Moment.
Topics: Acidosis; Alcoholism; Antidotes; Diagnostic Errors; Female; Fomepizole; Humans; Medical Errors; Meth | 2016 |
Cost-effectiveness of hospital treatment and outcomes of acute methanol poisoning during the Czech Republic mass poisoning outbreak.
Topics: Adult; Alcoholism; Antidotes; Cost-Benefit Analysis; Cross-Sectional Studies; Czech Republic; Diseas | 2017 |
Head CT in patient with metabolic acidosis.
Topics: Acid-Base Imbalance; Acidosis; Adult; Alcoholism; Anisocoria; Antidotes; Bicarbonates; Cerebral Hemo | 2008 |
Agitation by sedation.
Topics: Alcoholism; Antidotes; Chemistry, Pharmaceutical; Ethylene Glycol; Female; Fomepizole; Humans; Hypno | 2003 |
Ethanol: its adverse effects upon the hypothalamic-pituitary-gonadal axis.
Topics: Alcoholism; Animals; Cells, Cultured; Estradiol; Ethanol; Follicle Stimulating Hormone; Fomepizole; | 1983 |
Effects of intravenous ethanol and of 4-methylpyrazole on alcohol drinking in alcohol-preferring rats.
Topics: Alcohol Drinking; Alcoholism; Animals; Disease Models, Animal; Ethanol; Fomepizole; Humans; Male; Py | 1982 |
The disulfiram (Antabuse)-Alcohol reaction in male alcoholics: its efficient management by 4-methylpyrazole.
Topics: Adult; Alcohol Oxidoreductases; Alcoholism; Cyanamide; Disulfiram; Fomepizole; Humans; Male; Pyrazol | 1981 |
The content and activity of cytochrome P450 2E1 in liver microsomes from alcohol-preferring and non-preferring rats.
Topics: Alcoholism; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Fomepizole; Immunoblotting; M | 1992 |