Page last updated: 2024-10-27

fomepizole and Acute Kidney Injury

fomepizole has been researched along with Acute Kidney Injury in 10 studies

Fomepizole: A pyrazole and competitive inhibitor of ALCOHOL DEHYDROGENASE that is used for the treatment of poisoning by ETHYLENE GLYCOL or METHANOL.
fomepizole : A member of the class of pyrazoles that is 1H-pyrazole substituted by a methyl group at position 4.

Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.

Research Excerpts

ExcerptRelevanceReference
"Ingestion of ethylene glycol may be an important contributor in patients with metabolic acidosis of unknown cause and subsequent renal failure."8.81Treatment of ethylene glycol poisoning. ( Archie, TE; Ferguson, DR; Piccaro, JC; Scalley, RD; Smart, ML, 2002)
"Ingestion of ethylene glycol may be an important contributor in patients with metabolic acidosis of unknown cause and subsequent renal failure."4.81Treatment of ethylene glycol poisoning. ( Archie, TE; Ferguson, DR; Piccaro, JC; Scalley, RD; Smart, ML, 2002)
"Ethylene glycol is an inexpensive, readily available substance that may be associated with accidental or intentional toxicity."1.32Ethylene glycol toxicity. ( Cox, RD; Phillips, WJ, 2004)
"Fomepizole is an effective alternative to ethanol in the treatment of ethylene glycol poisoning."1.30Fomepizole in treatment of uncomplicated ethylene glycol poisoning. ( Baud, FJ; Borron, SW; Mégarbane, B, 1999)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (30.00)18.2507
2000's3 (30.00)29.6817
2010's2 (20.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Beaulieu, J1
Roberts, DM1
Gosselin, S1
Hoffman, RS1
Lavergne, V1
Hovda, KE1
Megarbane, B2
Lung, D1
Thanacoody, R1
Ghannoum, M1
Akakpo, JY1
Ramachandran, A1
Orhan, H1
Curry, SC1
Rumack, BH1
Jaeschke, H1
Kettritz, R1
Ritter, T1
Rudolph, B1
Luft, FC1
Lung, DD1
Kearney, TE1
Brasiel, JA1
Olson, KR1
Rastogi, A1
Itagaki, B1
Bajwa, M1
Kraut, JA1
Scalley, RD1
Ferguson, DR1
Piccaro, JC1
Smart, ML1
Archie, TE1
Cox, RD1
Phillips, WJ1
Faessel, H1
Houze, P1
Baud, FJ2
Scherrmann, JM1
Borron, SW1
Goldfarb, DS1

Reviews

2 reviews available for fomepizole and Acute Kidney Injury

ArticleYear
Treating ethylene glycol poisoning with alcohol dehydrogenase inhibition, but without extracorporeal treatments: a systematic review.
    Clinical toxicology (Philadelphia, Pa.), 2022, Volume: 60, Issue:7

    Topics: Acidosis; Acute Kidney Injury; Alcohol Dehydrogenase; Antidotes; Ethanol; Ethylene Glycol; Fomepizol

2022
Treatment of ethylene glycol poisoning.
    American family physician, 2002, Sep-01, Volume: 66, Issue:5

    Topics: Acidosis; Acute Kidney Injury; Adult; Antidotes; Ethylene Glycol; Fomepizole; Humans; Male; Osmolar

2002

Other Studies

8 other studies available for fomepizole and Acute Kidney Injury

ArticleYear
4-methylpyrazole protects against acetaminophen-induced acute kidney injury.
    Toxicology and applied pharmacology, 2020, 12-15, Volume: 409

    Topics: Acetaminophen; Acute Kidney Injury; Adolescent; Adult; Aged; Animals; Chemical and Drug Induced Live

2020
The Case | Acid-base diagnoses in the 21st century.
    Kidney international, 2017, Volume: 92, Issue:5

    Topics: Acidosis; Acute Kidney Injury; Alcoholic Intoxication; Alcoholism; Antidotes; Creatinine; Ethylene G

2017
Predictors of Death and Prolonged Renal Insufficiency in Ethylene Glycol Poisoning.
    Journal of intensive care medicine, 2015, Volume: 30, Issue:5

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Antidotes; California; Cause of Dea

2015
Spurious elevation in serum creatinine caused by ingestion of nitromethane: implication for the diagnosis and treatment of methanol intoxication.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2008, Volume: 52, Issue:1

    Topics: Acidosis; Acute Kidney Injury; Adult; Creatinine; Female; Follow-Up Studies; Fomepizole; Humans; Kid

2008
Ethylene glycol toxicity.
    Military medicine, 2004, Volume: 169, Issue:8

    Topics: Acidosis; Acute Kidney Injury; Adolescent; Critical Care; Emergency Treatment; Ethylene Glycol; Fema

2004
4-methylpyrazole monitoring during haemodialysis of ethylene glycol intoxicated patients.
    European journal of clinical pharmacology, 1995, Volume: 49, Issue:3

    Topics: Acute Kidney Injury; Adult; Antidotes; Ethylene Glycols; Fomepizole; Humans; Male; Middle Aged; Pyra

1995
Fomepizole in treatment of uncomplicated ethylene glycol poisoning.
    Lancet (London, England), 1999, Sep-04, Volume: 354, Issue:9181

    Topics: Acute Kidney Injury; Adult; Antidotes; Ethylene Glycol; Female; Fomepizole; Humans; Male; Pyrazoles;

1999
Fomepizole for ethylene-glycol poisoning.
    Lancet (London, England), 1999, Nov-06, Volume: 354, Issue:9190

    Topics: Acute Kidney Injury; Antidotes; Ethylene Glycol; Fomepizole; Health Services Accessibility; Humans;

1999