fomepizole has been researched along with Acidosis in 46 studies
Fomepizole: A pyrazole and competitive inhibitor of ALCOHOL DEHYDROGENASE that is used for the treatment of poisoning by ETHYLENE GLYCOL or METHANOL.
fomepizole : A member of the class of pyrazoles that is 1H-pyrazole substituted by a methyl group at position 4.
Acidosis: A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ethylene glycol is metabolized to toxic metabolites that cause acute kidney injury, metabolic acidemia, and death." | 9.22 | Treating ethylene glycol poisoning with alcohol dehydrogenase inhibition, but without extracorporeal treatments: a systematic review. ( Beaulieu, J; Ghannoum, M; Gosselin, S; Hoffman, RS; Hovda, KE; Lavergne, V; Lung, D; Megarbane, B; Roberts, DM; Thanacoody, R, 2022) |
| "Fomepizole appears to be safe and effective in the treatment of methanol poisoning." | 9.09 | Fomepizole for the treatment of methanol poisoning. ( Aaron, C; Brent, J; Kulig, K; McMartin, K; Phillips, S, 2001) |
| "Fomepizole is now the antidote of choice in methanol poisoning." | 8.84 | Expert opinion: fomepizole may ameliorate the need for hemodialysis in methanol poisoning. ( Hovda, KE; Jacobsen, D, 2008) |
| "Ingestion of ethylene glycol may be an important contributor in patients with metabolic acidosis of unknown cause and subsequent renal failure." | 8.81 | Treatment of ethylene glycol poisoning. ( Archie, TE; Ferguson, DR; Piccaro, JC; Scalley, RD; Smart, ML, 2002) |
| "Ethylene glycol (EG) toxicity is an important cause of toxic alcohol poisoning in the USA with over 5,000 exposures reported annually." | 8.31 | Mass Poisoning From Ethylene Glycol at a U.S. Military Base. ( Banda, M; Forster, BM; Khayat, M; King, JD; Munoz, J; Owshalimpur, D; Petteys, SK; Shah, N; Sullivan, SB; Watson, M; White, WC, 2023) |
| "We present an unusual case of a coingestion of ethanol and 150-250 mL of pure 2BE, which resulted in rapid obtundation, severe airway edema, hypotension, and prolonged acidosis despite the coingestion of ethanol and the administration of a loading dose of fomepizole." | 7.76 | Fomepizole fails to prevent progression of acidosis in 2-butoxyethanol and ethanol coingestion. ( Dewitt, CR; Holmes, DT; Hung, T; Martz, W; Schreiber, W, 2010) |
| "Fomepizole may precipitate bradycardia and/or hypotension during hemodialysis." | 7.74 | Bradycardia and hypotension associated with fomepizole infusion during hemodialysis. ( Brignall, JL; Brubacher, JR; DeWitt, CR; Erhardt, GD; Kennedy, JR; Lam, GS; Lawson, EJ; Lepik, KJ; Purssell, RA, 2008) |
| "Ethylene glycol is a toxic alcohol which may induce significant toxicity when ingested accidentally or intentionally." | 6.72 | The three biological gaps and hyperoxaluria in ethylene glycol poisoning: case presentation and review. ( Ahmad, Y; Chiche, JD; Kissling, S; Liaudet, L; Ltaief, Z; Torrent, C, 2021) |
| "Diethylene glycol (DEG) is a clear, colorless, practically odorless, viscous, hygroscopic liquid with a sweetish taste." | 6.45 | Diethylene glycol poisoning. ( Beasley, DM; Schep, LJ; Slaughter, RJ; Temple, WA, 2009) |
| "Ethylene glycol intoxication is a rare but dangerous type of poisoning." | 6.40 | Diagnosis and treatment of an unusual cause of metabolic acidosis: ethylene glycol poisoning. ( Lejeune, P; Piagnerelli, M; Vanhaeverbeek, M, 1999) |
| "Methanol intoxication was suspected due to high anion gap metabolic acidosis (pH, 6." | 5.43 | A Rare Cause of Metabolic Acidosis: Fatal Transdermal Methanol Intoxication in an Infant. ( Aksu, N; Anil, AB; Anil, M; Bal, A; Can, FK; Gokalp, G; Sahbudak Bal, Z; Yavascan, O, 2016) |
| "Ethylene glycol is metabolized to toxic metabolites that cause acute kidney injury, metabolic acidemia, and death." | 5.22 | Treating ethylene glycol poisoning with alcohol dehydrogenase inhibition, but without extracorporeal treatments: a systematic review. ( Beaulieu, J; Ghannoum, M; Gosselin, S; Hoffman, RS; Hovda, KE; Lavergne, V; Lung, D; Megarbane, B; Roberts, DM; Thanacoody, R, 2022) |
| "Fomepizole appears to be safe and effective in the treatment of methanol poisoning." | 5.09 | Fomepizole for the treatment of methanol poisoning. ( Aaron, C; Brent, J; Kulig, K; McMartin, K; Phillips, S, 2001) |
| "I searched MEDLINE for articles published between 1969 and 2014 using the terms: toxic alcohols, serum osmolality, serum osmol gap, serum anion gap, metabolic acidosis, methanol, ethylene glycol, diethylene glycol, propylene glycol, and fomepizole." | 4.91 | Diagnosis of toxic alcohols: limitations of present methods. ( Kraut, JA, 2015) |
| " In many cases of pediatric ethylene glycol poisoning treated with fomepizole, hemodialysis may not be necessary despite high concentrations and the presence of metabolic acidosis." | 4.86 | Fomepizole for the treatment of pediatric ethylene and diethylene glycol, butoxyethanol, and methanol poisonings. ( Brent, J, 2010) |
| "Fomepizole is now the antidote of choice in methanol poisoning." | 4.84 | Expert opinion: fomepizole may ameliorate the need for hemodialysis in methanol poisoning. ( Hovda, KE; Jacobsen, D, 2008) |
| "Acute methanol poisoning is mainly the consequence of voluntary or accidental ingestion." | 4.83 | [Acute methanol intoxication: physiopathology, prognosis and treatment]. ( Hantson, PE, 2006) |
| "Ingestion of ethylene glycol may be an important contributor in patients with metabolic acidosis of unknown cause and subsequent renal failure." | 4.81 | Treatment of ethylene glycol poisoning. ( Archie, TE; Ferguson, DR; Piccaro, JC; Scalley, RD; Smart, ML, 2002) |
| "Ethylene glycol (EG) toxicity is an important cause of toxic alcohol poisoning in the USA with over 5,000 exposures reported annually." | 4.31 | Mass Poisoning From Ethylene Glycol at a U.S. Military Base. ( Banda, M; Forster, BM; Khayat, M; King, JD; Munoz, J; Owshalimpur, D; Petteys, SK; Shah, N; Sullivan, SB; Watson, M; White, WC, 2023) |
| "Ethylene glycol toxicity is a known cause of anion gap metabolic acidosis, with the presence of an osmolar gap and the right clinical context suggesting to the diagnosis." | 3.88 | Lactate gap as a tool in identifying ethylene glycol poisoning. ( Jimenez, CA; Mckelvy, BJ; Sagar, AS, 2018) |
| "02; (2) 2 Na-dependent acid extruders and a Cl-dependent acid loading carrier exist and are functional; (3) alcohol functions in a concentration-dependent manner to reduce pHi and increase NHE activity, but it does not affect CHE activity; and (4) fomepizole, a specific alcohol dehydrogenase inhibitor, does not change the intracellular acidosis and NHE activity-induced by alcohol, whereas 3-amino-1, 2,4-trizole, a specific catalase inhibitor, entirely abolishes these effects." | 3.77 | Functional characterization of transmembrane intracellular pH regulators and mechanism of alcohol-induced intracellular acidosis in human umbilical cord blood stem cell-like cells. ( Chen, MH; Chen, WH; Lee, CY; Liu, JY; Loh, SH; Ou, CC; Tsai, CS; Tsai, YT, 2011) |
| "We present an unusual case of a coingestion of ethanol and 150-250 mL of pure 2BE, which resulted in rapid obtundation, severe airway edema, hypotension, and prolonged acidosis despite the coingestion of ethanol and the administration of a loading dose of fomepizole." | 3.76 | Fomepizole fails to prevent progression of acidosis in 2-butoxyethanol and ethanol coingestion. ( Dewitt, CR; Holmes, DT; Hung, T; Martz, W; Schreiber, W, 2010) |
| "Fomepizole may precipitate bradycardia and/or hypotension during hemodialysis." | 3.74 | Bradycardia and hypotension associated with fomepizole infusion during hemodialysis. ( Brignall, JL; Brubacher, JR; DeWitt, CR; Erhardt, GD; Kennedy, JR; Lam, GS; Lawson, EJ; Lepik, KJ; Purssell, RA, 2008) |
| "Based on our data, methanol-poisoned patients with moderate metabolic acidosis and methanol levels up to 19 mmol/L (60 mg/L) may safely be treated with bicarbonate and fomepizole only, without dialysis." | 3.73 | Methanol and formate kinetics during treatment with fomepizole. ( Andersson, KS; Hovda, KE; Jacobsen, D; Urdal, P, 2005) |
| "Ethylene glycol is a toxic alcohol which may induce significant toxicity when ingested accidentally or intentionally." | 2.72 | The three biological gaps and hyperoxaluria in ethylene glycol poisoning: case presentation and review. ( Ahmad, Y; Chiche, JD; Kissling, S; Liaudet, L; Ltaief, Z; Torrent, C, 2021) |
| "The information on burden of alcohol abuse in Iran is scarce." | 2.53 | A Brief Review on Toxic Alcohols: Management Strategies. ( Hassanian-Moghaddam, H; Zamani, N, 2016) |
| "Fomepizole has few side effects and is easy to use in practice and it may obviate the need for haemodialysis in some, but not all, patients." | 2.53 | Antidotes for poisoning by alcohols that form toxic metabolites. ( Hovda, KE; Jacobsen, D; McMartin, K, 2016) |
| "Diethylene glycol (DEG) is a clear, colorless, practically odorless, viscous, hygroscopic liquid with a sweetish taste." | 2.45 | Diethylene glycol poisoning. ( Beasley, DM; Schep, LJ; Slaughter, RJ; Temple, WA, 2009) |
| "Ethylene glycol intoxication is a rare but dangerous type of poisoning." | 2.40 | Diagnosis and treatment of an unusual cause of metabolic acidosis: ethylene glycol poisoning. ( Lejeune, P; Piagnerelli, M; Vanhaeverbeek, M, 1999) |
| "Diethylene glycol (DEG) is an industrial solvent with many uses, including brake fluids." | 1.72 | Symptomatic Diethylene Glycol Ingestion Successfully Treated with Fomepizole Monotherapy. ( Clark, RF; Corbett, B; Lasoff, DR; Seltzer, JA, 2022) |
| "Methanol intoxication was suspected due to high anion gap metabolic acidosis (pH, 6." | 1.43 | A Rare Cause of Metabolic Acidosis: Fatal Transdermal Methanol Intoxication in an Infant. ( Aksu, N; Anil, AB; Anil, M; Bal, A; Can, FK; Gokalp, G; Sahbudak Bal, Z; Yavascan, O, 2016) |
| " Although these studies suggest that either metabolite may be involved in producing kidney toxicity, the unexpected renal accumulation of DGA at toxic doses of DEG suggests that it must also be considered a possible toxic metabolite of DEG." | 1.37 | Role of tissue metabolite accumulation in the renal toxicity of diethylene glycol. ( Bartels, M; Besenhofer, LM; Filary, MJ; Latimer, B; McLaren, MC; McMartin, KE; Perala, AW, 2011) |
| "Methanol poisoning is a hazardous intoxication characterized by visual impairment and formic acidemia." | 1.36 | Ranitidine as an alcohol dehydrogenase inhibitor in acute methanol toxicity in rats. ( Attalla, SM; El-Bakary, AA; El-Dakrory, SA; Hasanein, NA; Malek, HA, 2010) |
| " She received fomepizole at dosing corrected for hemodialysis(HD), and bicarbonate via multiple boluses and continuous infusion." | 1.35 | Head CT in patient with metabolic acidosis. ( Babu, KM; Boyer, EW; Rosenbaum, CD, 2008) |
| "Treatment of methanol poisoning includes administration of buffer, antidote and hemodialysis." | 1.33 | Fomepizole may change indication for hemodialysis in methanol poisoning: prospective study in seven cases. ( Froyshov, S; Gudmundsdottir, H; Hovda, KE; Jacobsen, D; Rudberg, N, 2005) |
| "Ethylene glycol is an inexpensive, readily available substance that may be associated with accidental or intentional toxicity." | 1.32 | Ethylene glycol toxicity. ( Cox, RD; Phillips, WJ, 2004) |
| "The fomepizole treatment protocol (10 mg/kg by i." | 1.30 | Fomepizole (4-methylpyrazole) in fatal methanol poisoning with early CT scan cerebral lesions. ( Bonmarchand, G; Callonnec, F; Droy, JM; Girault, C; Leroy, J; Moritz, F; Tamion, F, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.17) | 18.7374 |
| 1990's | 2 (4.35) | 18.2507 |
| 2000's | 18 (39.13) | 29.6817 |
| 2010's | 18 (39.13) | 24.3611 |
| 2020's | 7 (15.22) | 2.80 |
| Authors | Studies |
|---|---|
| Ahmad, Y | 1 |
| Kissling, S | 1 |
| Torrent, C | 1 |
| Chiche, JD | 1 |
| Liaudet, L | 1 |
| Ltaief, Z | 1 |
| Beaulieu, J | 1 |
| Roberts, DM | 1 |
| Gosselin, S | 1 |
| Hoffman, RS | 1 |
| Lavergne, V | 1 |
| Hovda, KE | 6 |
| Megarbane, B | 1 |
| Lung, D | 1 |
| Thanacoody, R | 1 |
| Ghannoum, M | 1 |
| Seltzer, JA | 1 |
| Corbett, B | 1 |
| Lasoff, DR | 1 |
| Clark, RF | 1 |
| Shah, N | 1 |
| Khayat, M | 1 |
| Owshalimpur, D | 1 |
| Banda, M | 1 |
| Munoz, J | 1 |
| White, WC | 1 |
| Forster, BM | 1 |
| Petteys, SK | 1 |
| Sullivan, SB | 1 |
| Watson, M | 1 |
| King, JD | 1 |
| Inman, B | 1 |
| Maddry, JK | 1 |
| Ng, PC | 1 |
| Koyfman, A | 1 |
| Long, B | 1 |
| Cervantes, CE | 1 |
| Chu, A | 1 |
| Heller, D | 1 |
| Lemont, M | 1 |
| Mullins, ME | 1 |
| Yeager, LH | 1 |
| Freeman, WE | 1 |
| Kettritz, R | 1 |
| Ritter, T | 1 |
| Rudolph, B | 1 |
| Luft, FC | 1 |
| Sagar, AS | 1 |
| Jimenez, CA | 1 |
| Mckelvy, BJ | 1 |
| Zakharov, S | 1 |
| Pelclova, D | 1 |
| Urban, P | 1 |
| Navratil, T | 1 |
| Diblik, P | 1 |
| Kuthan, P | 1 |
| Hubacek, JA | 1 |
| Miovsky, M | 1 |
| Klempir, J | 1 |
| Vaneckova, M | 1 |
| Seidl, Z | 1 |
| Pilin, A | 1 |
| Fenclova, Z | 1 |
| Petrik, V | 1 |
| Kotikova, K | 1 |
| Nurieva, O | 1 |
| Ridzon, P | 1 |
| Rulisek, J | 1 |
| Komarc, M | 1 |
| Meng, X | 1 |
| Paul, S | 1 |
| Federman, DJ | 1 |
| Kraut, JA | 2 |
| Sahbudak Bal, Z | 1 |
| Can, FK | 1 |
| Anil, AB | 1 |
| Bal, A | 1 |
| Anil, M | 1 |
| Gokalp, G | 1 |
| Yavascan, O | 1 |
| Aksu, N | 1 |
| McMartin, K | 2 |
| Jacobsen, D | 4 |
| Schoen, JC | 1 |
| Cain, MR | 1 |
| Robinson, JA | 1 |
| Schiltz, BM | 1 |
| Mannenbach, MS | 1 |
| Himmel, ME | 1 |
| Lam, K | 1 |
| Fralick, M | 1 |
| Maiti, A | 1 |
| Das, A | 1 |
| Hassanian-Moghaddam, H | 1 |
| Zamani, N | 1 |
| Collister, D | 1 |
| Duff, G | 1 |
| Palatnick, W | 1 |
| Komenda, P | 1 |
| Tangri, N | 1 |
| Hingwala, J | 1 |
| Lepik, KJ | 1 |
| Brubacher, JR | 1 |
| DeWitt, CR | 2 |
| Lam, GS | 1 |
| Lawson, EJ | 1 |
| Erhardt, GD | 1 |
| Purssell, RA | 1 |
| Kennedy, JR | 1 |
| Brignall, JL | 1 |
| Rastogi, A | 1 |
| Itagaki, B | 1 |
| Bajwa, M | 1 |
| Wallace, EA | 1 |
| Green, AS | 1 |
| Babu, KM | 1 |
| Rosenbaum, CD | 1 |
| Boyer, EW | 1 |
| Brent, J | 3 |
| Schep, LJ | 1 |
| Slaughter, RJ | 1 |
| Temple, WA | 1 |
| Beasley, DM | 1 |
| El-Bakary, AA | 1 |
| El-Dakrory, SA | 1 |
| Attalla, SM | 1 |
| Hasanein, NA | 1 |
| Malek, HA | 1 |
| Hung, T | 1 |
| Martz, W | 1 |
| Schreiber, W | 1 |
| Holmes, DT | 1 |
| Besenhofer, LM | 1 |
| McLaren, MC | 1 |
| Latimer, B | 1 |
| Bartels, M | 1 |
| Filary, MJ | 1 |
| Perala, AW | 1 |
| McMartin, KE | 1 |
| Tsai, YT | 1 |
| Liu, JY | 1 |
| Lee, CY | 1 |
| Tsai, CS | 1 |
| Chen, MH | 1 |
| Ou, CC | 1 |
| Chen, WH | 1 |
| Loh, SH | 1 |
| Lapatto-Reiniluoto, O | 1 |
| Ikäheimo, R | 1 |
| Scalley, RD | 1 |
| Ferguson, DR | 1 |
| Piccaro, JC | 1 |
| Smart, ML | 1 |
| Archie, TE | 1 |
| Osterhoudt, KC | 1 |
| Kostic, MA | 1 |
| Dart, RC | 1 |
| Caravati, EM | 1 |
| Heileson, HL | 1 |
| Jones, M | 1 |
| Cox, RD | 1 |
| Phillips, WJ | 1 |
| LoVecchio, F | 1 |
| Sawyers, B | 1 |
| Thole, D | 1 |
| Beuler, MC | 1 |
| Winchell, J | 1 |
| Curry, SC | 1 |
| Andersson, KS | 1 |
| Urdal, P | 1 |
| Froyshov, S | 1 |
| Gudmundsdottir, H | 1 |
| Rudberg, N | 1 |
| Hantson, PE | 1 |
| Tiamfook-Morgan, TO | 1 |
| Brown, DF | 1 |
| Nadel, ES | 1 |
| Girault, C | 1 |
| Tamion, F | 1 |
| Moritz, F | 1 |
| Callonnec, F | 1 |
| Droy, JM | 1 |
| Bonmarchand, G | 1 |
| Leroy, J | 1 |
| Piagnerelli, M | 1 |
| Lejeune, P | 1 |
| Vanhaeverbeek, M | 1 |
| Phillips, S | 1 |
| Aaron, C | 1 |
| Kulig, K | 1 |
| Jeganathan, PS | 1 |
| Namasivayam, A | 1 |
16 reviews available for fomepizole and Acidosis
| Article | Year |
|---|---|
The three biological gaps and hyperoxaluria in ethylene glycol poisoning: case presentation and review.
Topics: Acidosis; Antidotes; Delayed Diagnosis; Ethylene Glycol; Female; Fomepizole; Humans; Hyperoxaluria; | 2021 |
Treating ethylene glycol poisoning with alcohol dehydrogenase inhibition, but without extracorporeal treatments: a systematic review.
Topics: Acidosis; Acute Kidney Injury; Alcohol Dehydrogenase; Antidotes; Ethanol; Ethylene Glycol; Fomepizol | 2022 |
High risk and low prevalence diseases: Toxic alcohol ingestion.
Topics: Acidosis; Eating; Ethanol; Fomepizole; Humans; Methanol; Prevalence | 2023 |
Metabolic and mitochondrial treatments for severe paracetamol poisoning: a systematic review.
Topics: Acetaminophen; Acetylcysteine; Acidosis; Animals; Antidotes; Cimetidine; Drug Overdose; Edetic Acid; | 2020 |
Diagnosis of toxic alcohols: limitations of present methods.
Topics: Acid-Base Equilibrium; Acidosis; Alcohols; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Me | 2015 |
Antidotes for poisoning by alcohols that form toxic metabolites.
Topics: Acidosis; Antidotes; Ethanol; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Methanol; Pyraz | 2016 |
A Brief Review on Toxic Alcohols: Management Strategies.
Topics: 2-Propanol; Acidosis; Alcoholism; Antidotes; Ethanol; Ethylene Glycol; Fomepizole; Humans; Iran; Met | 2016 |
Expert opinion: fomepizole may ameliorate the need for hemodialysis in methanol poisoning.
Topics: Acidosis; Antidotes; Bicarbonates; Drug Therapy, Combination; Fomepizole; Humans; Methanol; Poisonin | 2008 |
Fomepizole for ethylene glycol and methanol poisoning.
Topics: Acidosis; Adult; Antidotes; Blood Chemical Analysis; Ethylene Glycol; Fomepizole; Humans; Male; Meth | 2009 |
Diethylene glycol poisoning.
Topics: Acidosis; Animals; Antidotes; Drug Contamination; Environmental Exposure; Ethanol; Ethylene Glycols; | 2009 |
Fomepizole for the treatment of pediatric ethylene and diethylene glycol, butoxyethanol, and methanol poisonings.
Topics: Acidosis; Adult; Alcoholism; Antidotes; Bicarbonates; Child; Disease Progression; Ethanol; Ethylene | 2010 |
[Surrogate alcohol poisonings].
Topics: Acidosis; Antidotes; Ethylene Glycol; Finland; Fomepizole; Humans; Methanol; Poisoning; Pyrazoles; R | 2012 |
Treatment of ethylene glycol poisoning.
Topics: Acidosis; Acute Kidney Injury; Adult; Antidotes; Ethylene Glycol; Fomepizole; Humans; Male; Osmolar | 2002 |
Rethinking the toxic methanol level.
Topics: Acidosis; Adolescent; Adult; Antidotes; Bicarbonates; Child, Preschool; Dose-Response Relationship, | 2003 |
[Acute methanol intoxication: physiopathology, prognosis and treatment].
Topics: Acidosis; Acute Disease; Antidotes; Central Nervous System; Fomepizole; Formaldehyde; Humans; Liver; | 2006 |
Diagnosis and treatment of an unusual cause of metabolic acidosis: ethylene glycol poisoning.
Topics: Acid-Base Imbalance; Acidosis; Alcohol Dehydrogenase; Antidotes; Bone Marrow Diseases; Enzyme Inhibi | 1999 |
1 trial available for fomepizole and Acidosis
| Article | Year |
|---|---|
Fomepizole for the treatment of methanol poisoning.
Topics: Acidosis; Adolescent; Adult; Alcohol Dehydrogenase; Antidotes; Enzyme Inhibitors; Female; Fomepizole | 2001 |
29 other studies available for fomepizole and Acidosis
| Article | Year |
|---|---|
Symptomatic Diethylene Glycol Ingestion Successfully Treated with Fomepizole Monotherapy.
Topics: Acidosis; Adult; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Antidotes; Eating; Ethylene Glycol; | 2022 |
Mass Poisoning From Ethylene Glycol at a U.S. Military Base.
Topics: Acidosis; Ethylene Glycol; Fomepizole; Humans; Military Facilities; Poisoning; Renal Dialysis | 2023 |
Early dialysis in a rare case of combined toxic alcohols ingestion.
Topics: Acidosis; Adult; Alcohols; Antidotes; Bicarbonates; Buffers; Combined Modality Therapy; Eating; Ethy | 2020 |
The Case | Acid-base diagnoses in the 21st century.
Topics: Acidosis; Acute Kidney Injury; Alcoholic Intoxication; Alcoholism; Antidotes; Creatinine; Ethylene G | 2017 |
Lactate gap as a tool in identifying ethylene glycol poisoning.
Topics: Acidosis; Antidotes; Diagnosis, Differential; Dialysis; Ethylene Glycol; Fomepizole; Humans; Lactic | 2018 |
Czech mass methanol outbreak 2012: epidemiology, challenges and clinical features.
Topics: Acidosis; Adolescent; Adult; Aged; Antidotes; Biomarkers; Consciousness; Czech Republic; Disease Out | 2014 |
Metabolic acidosis in a patient with isopropyl alcohol intoxication: a case report.
Topics: 2-Propanol; Acidosis; Alcoholism; Antidotes; Female; Fomepizole; Humans; Middle Aged; Pyrazoles | 2015 |
A Rare Cause of Metabolic Acidosis: Fatal Transdermal Methanol Intoxication in an Infant.
Topics: Acidosis; Antidotes; Fatal Outcome; Female; Fomepizole; Humans; Infant; Methanol; Pyrazoles; Renal D | 2016 |
Adolescent Presents With Altered Mental Status and Elevated Anion Gap After Suicide Attempt by Ethylene Glycol Ingestion.
Topics: Acidosis; Adolescent; Depressive Disorder, Major; Diagnosis, Differential; Ethylene Glycol; Fomepizo | 2016 |
Hemodialysis in a Healthy Patient--A Case of an Erroneous Laboratory Result: A Teachable Moment.
Topics: Acidosis; Alcoholism; Antidotes; Diagnostic Errors; Female; Fomepizole; Humans; Medical Errors; Meth | 2016 |
A man with altered mental status and metabolic acidosis.
Topics: Acid-Base Equilibrium; Acidosis; Antidotes; Confusion; Dyspnea; Ethylene Glycol; Fomepizole; Hematur | 2016 |
A Methanol Intoxication Outbreak From Recreational Ingestion of Fracking Fluid.
Topics: Acid-Base Equilibrium; Acidosis; Adult; Antidotes; Disease Outbreaks; Eating; Fomepizole; Humans; Hy | 2017 |
Bradycardia and hypotension associated with fomepizole infusion during hemodialysis.
Topics: Acidosis; Antidotes; Blood Pressure; Bradycardia; Dose-Response Relationship, Drug; Ethylene Glycol; | 2008 |
Spurious elevation in serum creatinine caused by ingestion of nitromethane: implication for the diagnosis and treatment of methanol intoxication.
Topics: Acidosis; Acute Kidney Injury; Adult; Creatinine; Female; Follow-Up Studies; Fomepizole; Humans; Kid | 2008 |
Methanol toxicity secondary to inhalant abuse in adult men.
Topics: Acidosis; Adult; Antidotes; Ethanol; Ethnicity; Fomepizole; Hispanic or Latino; Humans; Indians, Nor | 2009 |
Head CT in patient with metabolic acidosis.
Topics: Acid-Base Imbalance; Acidosis; Adult; Alcoholism; Anisocoria; Antidotes; Bicarbonates; Cerebral Hemo | 2008 |
Ranitidine as an alcohol dehydrogenase inhibitor in acute methanol toxicity in rats.
Topics: Acidosis; Alcohol Dehydrogenase; Animals; Antidotes; Enzyme Inhibitors; Ethanol; Fomepizole; Formate | 2010 |
Fomepizole fails to prevent progression of acidosis in 2-butoxyethanol and ethanol coingestion.
Topics: Acidosis; Alcohol Dehydrogenase; Antidotes; Disease Progression; Ethanol; Ethylene Glycols; Fomepizo | 2010 |
Role of tissue metabolite accumulation in the renal toxicity of diethylene glycol.
Topics: Acetates; Acidosis; Animals; Antidotes; Ethylene Glycols; Fomepizole; Kidney; Kidney Diseases; Male; | 2011 |
Functional characterization of transmembrane intracellular pH regulators and mechanism of alcohol-induced intracellular acidosis in human umbilical cord blood stem cell-like cells.
Topics: Acidosis; Amitrole; Antigens, CD34; Antiporters; Catalase; Cells, Cultured; Dose-Response Relationsh | 2011 |
Fomepizole therapy for pediatric butoxyethanol intoxication.
Topics: Acidosis; Adult; Antidotes; Ethylene Glycols; Female; Fomepizole; Humans; Pyrazoles; Solvents; Suici | 2002 |
Treatment of severe pediatric ethylene glycol intoxication without hemodialysis.
Topics: Acidosis; Adolescent; Antidotes; Bicarbonates; Child; Creatine; Disease Progression; Ethylene Glycol | 2004 |
Ethylene glycol toxicity.
Topics: Acidosis; Acute Kidney Injury; Adolescent; Critical Care; Emergency Treatment; Ethylene Glycol; Fema | 2004 |
Outcomes following abuse of methanol-containing carburetor cleaners.
Topics: Acidosis; Adolescent; Adult; Antidotes; Ethanol; Female; Fluid Therapy; Fomepizole; Humans; Inhalati | 2004 |
Methanol and formate kinetics during treatment with fomepizole.
Topics: Acidosis; Adult; Aged; Antidotes; Bicarbonates; Chromatography, Gas; Dialysis; Fomepizole; Formates; | 2005 |
Fomepizole may change indication for hemodialysis in methanol poisoning: prospective study in seven cases.
Topics: Acidosis; Adult; Aged; Antidotes; Female; Follow-Up Studies; Fomepizole; Humans; Male; Methanol; Mid | 2005 |
Change in mental status.
Topics: Acidosis; Adult; Antidotes; Confusion; Depression; Drug Overdose; Ethylene Glycol; Fomepizole; Human | 2007 |
Fomepizole (4-methylpyrazole) in fatal methanol poisoning with early CT scan cerebral lesions.
Topics: Acidosis; Adult; Alcohol Dehydrogenase; Antidotes; Brain; Coma; Dialysis; Enzyme Inhibitors; Fatal O | 1999 |
Role of acidosis in the changes of rat brain monoamines after methanol administration & effect of blocking methanol metabolism by 4-methyl pyrazole & 3-amino-1,2,4-triazole.
Topics: Acidosis; Amitrole; Animals; Brain Chemistry; Catecholamines; Fomepizole; Methanol; Pyrazoles; Rats; | 1988 |