Page last updated: 2024-08-17

folic acid and Sterility, Male

folic acid has been researched along with Sterility, Male in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's13 (34.21)29.6817
2010's17 (44.74)24.3611
2020's8 (21.05)2.80

Authors

AuthorsStudies
Akdogan, N; Bozkurt, A; Karabakan, M; Öztürk, M; Yaris, M1
Aston, K; Carrell, D; Chaney, K; Chen, Z; Clemons, T; DeVilbiss, E; Emery, B; Hotaling, J; Jenkins, T; Johnstone, E; Mills, JL; Mumford, SL; Perkins, N; Peterson, CM; Schisterman, E; Sjaarda, L; Sparks, A1
Fang, Y; Liu, C; Peng, M; Su, Y; Tang, Y; Wang, W; Yuan, H; Zhang, H; Zhang, X; Zhang, Y; Zhao, K1
Carrell, DT; Chen, Z; DeVilbiss, EA; Hotaling, JM; Johnstone, E; Mendola, P; Mills, JL; Mumford, SL; Perkins, NJ; Peterson, CM; Ryan, G; Schisterman, EF; Sjaarda, LA1
Campbell, B; Carrell, DT; Chaney, K; Chen, Z; Clemons, T; DeVilbiss, EA; Hammoud, AO; Johnstone, E; Lamb, D; Mendola, P; Mills, JL; Mumford, SL; Perkins, NJ; Peterson, CM; Robins, J; Ryan, G; Schisterman, EF; Sjaarda, LA; Summers, K; Van Voorhis, BJ1
Carrell, DT; Chaney, K; Chen, Z; Clemons, T; DeVilbiss, EA; Hotaling, J; Johnstone, E; Lamb, D; Mendola, P; Mills, JL; Mumford, SL; Perkins, NJ; Peterson, CM; Robins, J; Ryan, G; Schisterman, EF; Sjaarda, LA; Summers, K; Van Voorhis, BJ1
Han, RY; Liu, WJ; Ma, J; Qi, YN; Wang, SS1
Atanasova, PK; Dechev, IY; Stoyanova, RS; Tomov, SN1
De Toni, L; Di Nisio, A; Foresta, C; Francini-Pesenti, F; Garolla, A; Petre, GC; Vitagliano, A1
Hong, HH; Hu, Y; Lv, MQ; Ren, WJ; Sun, Y; Yu, XQ; Zhou, DX; Zhou, L1
Amirian, M; Irani, M; Latifnejad Roudsari, R; Lez, JL; Sadeghi, R1
Anserini, P; Canepa, P; Dal Lago, A; De Leo, C; Gallo, M; Licata, E; Rago, R; Rizzo, C; Scaruffi, P1
Mansoor, A; Mazhar, K; Micheal, S; Mirza, B; Qamar, R; Siddiqi, S; Ullah, N1
Buhling, K; Eulenburg, CZ; Laakmann, E; Schumacher, A1
Azizollahi, G; Azizollahi, S; Babaei, H; Baneshi, MR; Kianinejad, M; Nematollahi-mahani, SN1
Brincat, D; Calleja-Agius, J; Catania, S; Wismayer, PS1
Huang, X; Jiang, L; Li, H; Ni, W; Wu, A; Yang, H; Yang, X; Zhang, P1
Cao, HF; Li, CY; Li, F; Lin, WQ; Zhang, W1
Hua, L; Huang, Y; Li, J; Li, X; Liu, K; Shen, M; Wang, Z; Ye, J; Zhao, R1
Boonyarangkul, A; Chiamchanya, C; Vinayanuvattikhun, N; Visutakul, P1
Bodner, F; Chedraui, P; Imhof, M; Lipovac, M1
Dohle, GR; Goijen, HJ; Huijgen, NA; Laven, JS; Lindemans, J; Mulders, AG; Steegers-Theunissen, RP; Twigt, JM1
Boxmeer, JC; Eijkemans, MJ; Laven, JS; Lindemans, J; Macklon, NS; Romijn, JC; Smit, M; Steegers, EA; Steegers-Theunissen, RP; Utomo, E1
Dotta, A; Multigner, L; Oliva, A1
Safarinejad, MR; Safarinejad, S; Shafiei, N1
Carter, TC; Giwercman, A; Levine, RJ; Mills, JL; Molloy, AM; Murphy, LE; Qian, C; Strevens, H; Wide-Swensson, D1
Azizollahi, GH; Azizollahi, S; Baneshi, MR; Nematollahi-Mahani, SN; Safari, Z1
Ebisch, IM; Steegers-Theunissen, RP; Thomas, CM; van der Put, N; van Heerde, WL; Wong, WY1
Rossato, M1
Kelly, TL; Neaga, OR; Rozen, R; Schwahn, BC; Trasler, JM1
Block, G; Eskenazi, B; Kidd, SA; Marks, AR; Sloter, E; Wyrobek, AJ1
DE Jong, FH; Ebisch, IM; Pierik, FH; Steegers-Theunissen, RP; Thomas, CM1
Cha, KY; Jeong, YM; Kim, NK; Lee, HC; Lee, KW; Lee, S; Lee, SH; Song, SH1
Dhillon, VS; Husain, SA; Shahid, M1
Bezold, G; Lange, M; Peter, RU1
Chen, Q; Chia, SE; Mei, J; Ng, V1
Menkveld, R; Merkus, HM; Steegers-Theunissen, RP; Thomas, CM; Wong, WY; Zielhuis, GA1

Reviews

7 review(s) available for folic acid and Sterility, Male

ArticleYear
Dietary Supplements for Male Infertility: A Critical Evaluation of Their Composition.
    Nutrients, 2020, May-19, Volume: 12, Issue:5

    Topics: Arginine; Dietary Supplements; Folic Acid; Humans; Infertility, Male; Italy; Male; Meta-Analysis as Topic; Randomized Controlled Trials as Topic; Recommended Dietary Allowances; Selenium; Spermatozoa; Systematic Reviews as Topic; Treatment Outcome; Ubiquinone; Zinc

2020
Associations of C677T polymorphism in methylenetetrahydrofolate reductase (MTHFR) gene with male infertility risk: A meta-analysis.
    European journal of obstetrics, gynecology, and reproductive biology, 2017, Volume: 212

    Topics: Alleles; Case-Control Studies; Folic Acid; Humans; Infertility, Male; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Risk Factors

2017
The Effect of Folate and Folate Plus Zinc Supplementation on Endocrine Parameters and Sperm Characteristics in Sub-Fertile Men: A Systematic Review and Meta-Analysis.
    Urology journal, 2017, 08-29, Volume: 14, Issue:5

    Topics: Dietary Supplements; Folic Acid; Humans; Infertility, Male; Inhibins; Male; Sperm Count; Sperm Motility; Spermatozoa; Testosterone; Vitamin B Complex; Zinc

2017
MTHFR polymorphisms as risk for male infertility in Pakistan and its comparison with socioeconomic status in the world.
    Personalized medicine, 2019, Volume: 16, Issue:1

    Topics: Alleles; Case-Control Studies; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Infertility, Male; Male; Methylenetetrahydrofolate Reductase (NADPH2); Pakistan; Polymorphism, Single Nucleotide; Risk Factors; Social Class; White People

2019
Influence of oral vitamin and mineral supplementation on male infertility: a meta-analysis and systematic review.
    Reproductive biomedicine online, 2019, Volume: 39, Issue:2

    Topics: Acetylcysteine; Administration, Oral; Ascorbic Acid; Dietary Supplements; Docosahexaenoic Acids; Eicosapentaenoic Acid; Folic Acid; Humans; Infertility, Male; Male; Minerals; Randomized Controlled Trials as Topic; Selenium; Spermatozoa; Ubiquinone; Vitamin E; Vitamins

2019
Male factors in ART outcome prediction.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2015, Volume: 31, Issue:3

    Topics: Anti-Mullerian Hormone; Biomarkers; DNA Fragmentation; Female; Folic Acid; Homocysteine; Humans; Infertility, Male; Male; Pregnancy; Pregnancy Rate; Prognosis; Reactive Oxygen Species; Reproductive Techniques, Assisted; Spermatozoa; Treatment Outcome

2015
Role of genetic mutations in folate-related enzyme genes on Male Infertility.
    Scientific reports, 2015, Nov-09, Volume: 5

    Topics: Asthenozoospermia; Folic Acid; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Infertility, Male; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oligospermia; Polymorphism, Single Nucleotide; Risk Factors

2015

Trials

12 trial(s) available for folic acid and Sterility, Male

ArticleYear
The impact of zinc and folic acid supplementation on sperm DNA methylation: results from the folic acid and zinc supplementation randomized clinical trial (FAZST).
    Fertility and sterility, 2022, Volume: 117, Issue:1

    Topics: Adolescent; Adult; Dietary Supplements; DNA Methylation; Double-Blind Method; Female; Folic Acid; Humans; Infant, Newborn; Infertility, Male; Live Birth; Male; Middle Aged; Pregnancy; Pregnancy Rate; Semen Analysis; Spermatozoa; United States; Young Adult; Zinc

2022
Longitudinal semen parameter assessments and live birth: variability and implications for treatment strategies.
    Fertility and sterility, 2022, Volume: 118, Issue:5

    Topics: Female; Folic Acid; Humans; Infertility, Male; Live Birth; Male; Pregnancy; Pregnancy Rate; Prospective Studies; Semen; Zinc

2022
A Randomized Trial to Evaluate the Effects of Folic Acid and Zinc Supplementation on Male Fertility and Livebirth: Design and Baseline Characteristics.
    American journal of epidemiology, 2020, 01-31, Volume: 189, Issue:1

    Topics: Adolescent; Adult; Dietary Supplements; Double-Blind Method; Female; Fertilization in Vitro; Folic Acid; Humans; Infant, Newborn; Infertility, Male; Live Birth; Male; Middle Aged; Pregnancy; Research Design; Semen Analysis; Treatment Outcome; Young Adult; Zinc

2020
Effect of Folic Acid and Zinc Supplementation in Men on Semen Quality and Live Birth Among Couples Undergoing Infertility Treatment: A Randomized Clinical Trial.
    JAMA, 2020, 01-07, Volume: 323, Issue:1

    Topics: Adolescent; Adult; Dietary Supplements; DNA Fragmentation; Female; Fertilization in Vitro; Folic Acid; Humans; Infertility, Male; Live Birth; Male; Middle Aged; Semen; Semen Analysis; Sperm Count; Treatment Failure; Young Adult; Zinc

2020
Effects of supplement therapy on sperm parameters, protamine content and acrosomal integrity of varicocelectomized subjects.
    Journal of assisted reproduction and genetics, 2013, Volume: 30, Issue:4

    Topics: Acrosome; Adult; Dietary Supplements; Folic Acid; Humans; Infertility, Male; Male; Prospective Studies; Protamines; Sperm Count; Sperm Motility; Spermatogenesis; Spermatozoa; Varicocele; Zinc Sulfate

2013
Comparative Study of the Effects of Tamoxifen Citrate and Folate on Semen Quality of the Infertile Male with Semen Abnormality.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2015, Volume: 98, Issue:11

    Topics: Adult; Comet Assay; DNA Damage; Double-Blind Method; Estrogen Antagonists; Folic Acid; Humans; Infertility, Male; Male; Prospective Studies; Semen; Semen Analysis; Sperm Count; Sperm Motility; Spermatozoa; Tamoxifen; Thailand

2015
Comparison of the effect of a combination of eight micronutrients versus a standard mono preparation on sperm parameters.
    Reproductive biology and endocrinology : RB&E, 2016, Dec-09, Volume: 14, Issue:1

    Topics: Adult; Arginine; Carnitine; Drug Combinations; Folic Acid; Glutathione; Humans; Infertility, Male; Male; Micronutrients; Middle Aged; Selenium; Semen Analysis; Sperm Count; Sperm Motility; Spermatozoa; Ubiquinone; Vitamin E; Zinc

2016
Pentoxifylline and antioxidants improve sperm quality in male patients with varicocele.
    Fertility and sterility, 2009, Volume: 91, Issue:4 Suppl

    Topics: Adult; Antioxidants; Dose-Response Relationship, Drug; Drug Therapy, Combination; Folic Acid; Free Radical Scavengers; Humans; Infertility, Male; Male; Pentoxifylline; Reproductive Techniques, Assisted; Sperm Motility; Spermatozoa; Varicocele

2009
Effect of folic acid and zinc sulphate on endocrine parameters and seminal antioxidant level after varicocelectomy.
    Andrologia, 2014, Volume: 46, Issue:3

    Topics: Antioxidants; Drug Therapy, Combination; Folic Acid; Follicle Stimulating Hormone; Humans; Infertility, Male; Inhibins; Male; Nitric Oxide; Semen; Superoxide Dismutase; Testosterone; Varicocele; Zinc Sulfate

2014
C677T methylenetetrahydrofolate reductase polymorphism interferes with the effects of folic acid and zinc sulfate on sperm concentration.
    Fertility and sterility, 2003, Volume: 80, Issue:5

    Topics: Double-Blind Method; Female; Folic Acid; Gene Frequency; Humans; Infertility, Male; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Placebos; Sperm Count; Spermatozoa; Zinc Sulfate

2003
Does folic acid and zinc sulphate intervention affect endocrine parameters and sperm characteristics in men?
    International journal of andrology, 2006, Volume: 29, Issue:2

    Topics: Adult; Double-Blind Method; Endocrine System; Folic Acid; Follicle Stimulating Hormone; Humans; Infertility, Male; Inhibins; Male; Placebos; Semen; Sperm Count; Sperm Motility; Spermatozoa; Statistics, Nonparametric; Testosterone; Zinc; Zinc Sulfate

2006
Effects of folic acid and zinc sulfate on male factor subfertility: a double-blind, randomized, placebo-controlled trial.
    Fertility and sterility, 2002, Volume: 77, Issue:3

    Topics: Adult; Double-Blind Method; Folic Acid; Follow-Up Studies; Humans; Infertility, Male; Male; Semen; Sperm Count; Sperm Motility; Statistics, Nonparametric; Zinc Sulfate

2002

Other Studies

19 other study(ies) available for folic acid and Sterility, Male

ArticleYear
The effects of two different antioxidant combinations on sperm parameters.
    Urologia, 2022, Volume: 89, Issue:4

    Topics: Acetylcarnitine; Adult; Antioxidants; Ascorbic Acid; Carnitine; Citric Acid; Female; Folic Acid; Fructose; Humans; Infertility, Male; Male; Pregnancy; Selenium; Semen; Sperm Motility; Spermatozoa; Vitamin B 12; Vitamin E; Young Adult; Zinc

2022
Studying the mechanism of sperm DNA damage caused by folate deficiency.
    Journal of cellular and molecular medicine, 2022, Volume: 26, Issue:3

    Topics: Animals; DNA Damage; DNA Fragmentation; Folic Acid; Folic Acid Deficiency; Humans; Infertility, Male; Male; Mice; Semen; Sperm Count; Spermatozoa

2022
[Correlation of the levels of seminal plasma homocysteine, folate and cobalamin with semen parameters in obese men].
    Zhonghua nan ke xue = National journal of andrology, 2018, Volume: 24, Issue:10

    Topics: Folic Acid; Homocysteine; Humans; Infertility, Male; Male; Obesity; Semen; Semen Analysis; Sperm Count; Sperm Motility; Spermatozoa; Vitamin B 12

2018
Changes in the Level of DNA Fragmentation in Sperm Cells detected by Acridine Orange Test in Men with Sub/infertility Treated with Nutritional Supplement PAPA.
    Folia medica, 2020, 03-31, Volume: 62, Issue:1

    Topics: Acridine Orange; Adult; Antioxidants; Arginine; Asthenozoospermia; Carnitine; Dietary Supplements; DNA Fragmentation; Fluorescent Dyes; Folic Acid; Fructose; Glutathione Reductase; Humans; Infertility, Male; Male; Middle Aged; Oligospermia; Selenium; Spermatozoa; Sweetening Agents; Taurine; Ubiquinone; Vitamin E; Vitamins

2020
Combined treatment with myo-inositol, alpha-lipoic acid, folic acid and vitamins significantly improves sperm parameters of sub-fertile men: a multi-centric study.
    European review for medical and pharmacological sciences, 2018, Volume: 22, Issue:20

    Topics: Adult; Female; Folic Acid; Humans; Infertility, Male; Inositol; Male; Middle Aged; Pregnancy; Reactive Oxygen Species; Semen; Semen Analysis; Sperm Count; Sperm Motility; Spermatozoa; Thioctic Acid; Vitamins

2018
Lack of association between genetic polymorphisms in three folate-related enzyme genes and male infertility in the Chinese population.
    Journal of assisted reproduction and genetics, 2015, Volume: 32, Issue:3

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Azoospermia; China; Ferredoxin-NADP Reductase; Folic Acid; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Infertility, Male; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Single Nucleotide; Risk Factors

2015
Association of a miR-34b binding site single nucleotide polymorphism in the 3'-untranslated region of the methylenetetrahydrofolate reductase gene with susceptibility to male infertility.
    Genetics and molecular research : GMR, 2015, Oct-09, Volume: 14, Issue:4

    Topics: 3' Untranslated Regions; Adult; Folic Acid; Genotype; Homocysteine; Humans; Infertility, Male; Male; Methylenetetrahydrofolate Reductase (NADPH2); MicroRNAs; Middle Aged; Polymorphism, Single Nucleotide

2015
Effect of Medications for Gastric Acid-Related Symptoms on Total Motile Sperm Count and Concentration: A Case-Control Study in Men of Subfertile Couples from the Netherlands.
    Drug safety, 2017, Volume: 40, Issue:3

    Topics: Adult; Case-Control Studies; Folic Acid; Gastric Acid; Gastrointestinal Agents; Humans; Hydrogen-Ion Concentration; Infertility, Male; Male; Netherlands; Semen; Semen Analysis; Sperm Count; Sperm Motility; Spermatozoa

2017
Low folate in seminal plasma is associated with increased sperm DNA damage.
    Fertility and sterility, 2009, Volume: 92, Issue:2

    Topics: Adult; DNA Damage; Folic Acid; Humans; Infertility, Male; Male; Middle Aged; Semen; Spermatozoa

2009
Relationship between genetic polymorphisms of methylenetetrahydrofolate reductase (C677T, A1298C, and G1793A) as risk factors for idiopathic male infertility.
    Reproductive sciences (Thousand Oaks, Calif.), 2011, Volume: 18, Issue:3

    Topics: Case-Control Studies; DNA; Folic Acid; Genotype; Homocysteine; Humans; Infertility, Male; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Semen

2011
Folate and vitamin B12 in idiopathic male infertility.
    Asian journal of andrology, 2011, Volume: 13, Issue:6

    Topics: Adult; Case-Control Studies; Folic Acid; Homocysteine; Humans; Infertility, Male; Male; Middle Aged; Sweden; Vitamin B 12

2011
A genetic polymorphism and male fertility.
    Fertility and sterility, 2004, Volume: 81, Issue:5

    Topics: Folic Acid; Humans; Infertility, Male; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Sperm Count; Spermatozoa; Zinc Sulfate

2004
[Complementary medicine. Help from nature in infertility?].
    Praxis, 2004, Apr-28, Volume: 93, Issue:18

    Topics: Clinical Trials as Topic; Folic Acid; Humans; Infertility, Male; Male; Phytotherapy; Plant Extracts; Sperm Count; Zinc Sulfate

2004
Infertility in 5,10-methylenetetrahydrofolate reductase (MTHFR)-deficient male mice is partially alleviated by lifetime dietary betaine supplementation.
    Biology of reproduction, 2005, Volume: 72, Issue:3

    Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Animals; Betaine; Dietary Supplements; Drug Administration Schedule; Fertility; Fertility Agents, Male; Folic Acid; Germ Cells; Infertility, Male; Male; Methylation; Mice; Mice, Inbred BALB C; Mice, Knockout; Sperm Count; Spermatogenesis; Statistics, Nonparametric; Testis

2005
Antioxidant intake is associated with semen quality in healthy men.
    Human reproduction (Oxford, England), 2005, Volume: 20, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aging; Antioxidants; Ascorbic Acid; beta Carotene; Dietary Supplements; Folic Acid; Humans; Infertility, Male; Male; Middle Aged; Nutrition Assessment; Semen; Sperm Motility; Vitamin E; Zinc

2005
Association study of four polymorphisms in three folate-related enzyme genes with non-obstructive male infertility.
    Human reproduction (Oxford, England), 2006, Volume: 21, Issue:12

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Aged; Ferredoxin-NADP Reductase; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Humans; Infertility, Male; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Polymorphism, Single Nucleotide

2006
Associations of MTHFR DNMT3b 4977 bp deletion in mtDNA and GSTM1 deletion, and aberrant CpG island hypermethylation of GSTM1 in non-obstructive infertility in Indian men.
    Molecular human reproduction, 2007, Volume: 13, Issue:4

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Base Sequence; Case-Control Studies; CpG Islands; Deoxyguanosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; DNA, Mitochondrial; Folic Acid; Gene Frequency; Genetic Predisposition to Disease; Glutathione Transferase; Homocysteine; Humans; India; Infertility, Male; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; Sequence Deletion; Vitamin B 12; White People

2007
Homozygous methylenetetrahydrofolate reductase C677T mutation and male infertility.
    The New England journal of medicine, 2001, Apr-12, Volume: 344, Issue:15

    Topics: DNA Mutational Analysis; Folic Acid; Homozygote; Humans; Infertility, Male; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors

2001
[Comparison of seminal vitamin B12, folate, reactive oxygen species and various sperm parameters between fertile and infertile males].
    Wei sheng yan jiu = Journal of hygiene research, 2001, Volume: 30, Issue:2

    Topics: Adult; Folic Acid; Humans; Infertility, Male; Male; Reactive Oxygen Species; Semen; Sperm Count; Sperm Motility; Spermatozoa; Vitamin B 12

2001